Abstract This study aimed to resveratrol supplementation (at 5 or 10 mg/kg) and a hydroethanolic extract of canjiqueira fruits (150 mg/kg) on female SWISS mice. Total cholesterol, high-density lipoprotein (HDL), triglyceride levels, gestation rates, and embryonic implantation rates in their female Offspring was evaluated. In conclusion, the consumption of canjiqueira fruit extract altered the lipid profile of their female offspring, and did not impact their reproductive performance. Supplementing female SWISS mice with 10 mg/kg of resveratrol increased total cholesterol, triglycerides, and HDL levels, thereby enhancing the reproductive efficiency of their offspring.

ABSTRACT Popularly known as passion fruit, some species of the genus Passiflora are widely used in folk medicines, such as sedatives and tranquilizers in many countries. Although these plants are employed for the same purposes, research with different species of Passiflora has indicated their heterogeneous chemical compositions. Since different chemical compositions can result in varying degrees of therapeutic efficiency, quality control based on the chemical constituents of each species is essential. To that end, the aim of this study was to compare pharmacognostically species of Passiflora in order to establish a chromatographic profile for the quality control of drugs in herbal medicines containing passion fruit. The study was conducted by collecting samples of leaves from twelve Passiflora taxa (i.e., ten species and two forms of P. edulis) – P. actinia, P. alata, P. amethystina, P. capsularis, P. cincinnata, P. edulis f. flavicarpa, P. edulis f. edulis, P. incarnata, P. morifolia, P. urnifolia, P. coccinea, and P. setacea – from different locations and obtaining their chromatographic profiles via thin-layer chromatography and high-performance liquid chromatography. Both methods used the flavonoid C-glycosides isoorientin, orientin, vitexin, and isovitexin as reference compounds and could ultimately establish specific profiles for each species. The chromatographic analyses discussed here can be used to assist in determining the quality and authenticity of herbal drugs derived from Passiflora species.

This integrative review aimed to present a summary of the knowledge published by nurses on the conceptions of the social identity of the person with mental suffering. It included 15 articles selected from the databases, submitted to the adaptation of the questionnaire validated by Ursi-2005, for construction of a summary table. Publications from 2001 to 2011 were included which presented nurses among their authors; for the search, the descriptors were social identification and mental health and nursing. The results indicate that 66.7% of the phenomena studied in the articles refer to issues of ethnicity and all the publications revealed elements which contribute to the configuration of the social identity as a feeling of belonging, uprootedness, adaptation to a new culture, social support, political or historical-social happenings, stigmatization and autonomy. The absence of a theoretical conception of social identity in the studies did not stop the authors from listing contributions to the improvement of research and to nursing practices directed at people with mental suffering.

Revisión integrativa cuya finalidad fue presentar la síntesis del conocimiento publicado por enfermeros acerca de las concepciones de identidad social de la persona en sufrimiento mental. Fueron incluidos 15 artículos de las bases de datos seleccionadas y sometidos a la adaptación del cuestionario validado por Ursi-2005 para construcción de cuadro síntese. Se incluyeron publicaciones de 2001 a 2011 que presentasen en su autoría enfermeros y para la búsqueda fueron utilizados los descriptores identificación social and salud mental and enfermería. Los resultados apuntan que 66,7% de los fenómenos estudiados en los artículos se relacionan a cuestiones étnicas y todas las publicaciones revelan elementos que contribuyen para la configuración de la identidad social como sentimiento de pertenecer, desarraigar, adaptación a una nueva cultura, apoyo social, acontecimientos políticos o histórico-sociales, estigmatización y autonomía. La ausencia de la concepción teórica de identidad social en los estudios no ha impedido elencar contribuciones al perfeccionamiento de investigaciónes y a las prácticas de enfermería destinadas a las personas en sufrimiento mental.

Revisão integrativa objetivou apresentar a síntese do conhecimento publicado por enfermeiros sobre as concepções de identidade social da pessoa em sofrimento mental. Foram incluídos 15 artigos das bases de dados selecionadas e submetidos à adaptação do questionário validado por Ursi-2005 para construção de quadro síntese. Incluíram-se publicações de 2001 a 2011 que apresentasse em sua autoria enfermeiros, utilizou-se para a busca os descritores identificação social and saúde mental and enfermagem. Os resultados apontam que 66,7% dos fenômenos estudados nos artigos referem-se a questões étnicas e todas as publicações revelam elementos que contribuem para a configuração da identidade social como sentimento de pertença, desenraizamento, adaptação a uma nova cultura, apoio social, acontecimentos políticos ou histórico-sociais, estigmatização e autonomia. A ausência da concepção teórica de identidade social nos estudos não impediu elencar contribuições ao aperfeiçoamento de pesquisas e às práticas de enfermagem destinadas às pessoas em sofrimento mental.

Os óleos essenciais de Baccharis dracunculifolia e Baccharis uncinella, obtidos por hidrodestilação, foram caracterizados físico e quimicamente em relação ao seu rendimento, sua densidade relativa (d20(20)), seu índice de refração, sua solubilidade em etanol e sua composição química por meio de cromatografia gasosa acoplada à espectrometria de massas (CG/EM). Os resultados mostraram um rendimento de 1,5 e 1,65 mL/100g-1, uma densidade relativa (d20(20)) de 0,9151 e 0,9147, um índice de refração de 1,4593 e 1,4602, um poder rotatório de +1,99 e +2,18, a sua solubilidade em etanol 70% foi 3,0, em etanol 80% foi 1,0 e em etanol 96,5% também foi de 1,0, para o óleo de B. dracunculifolia e B. uncinella, respectivamente. Os resultados mostraram que os óleos avaliados são semelhantes, apresentando 26 compostos, com destaque para β-pineno, ε-nerolidol, limoneno e espatulenol.

The essential oils of Baccharis dracunculifolia and Baccharis uncinella, which were obtained by hydrodistillation, were physically and chemically characterized for their yield, relative density (d20(20)), refraction index, solubility in ethanol and chemical composition through gas chromatography coupled to mass spectrophotometry (GC/MS). The results showed a yield of 1.5 and 1.65 mL/100g-1, relative density (d20(20)) of 0.9151 and 0.9147, refraction index of 1.4593 and 1.4602, rotatory power of +1.99 and +2.18. Solubility in 70% ethanol was 3.0, in 80% ethanol was 1.0 and in 96.5% ethanol was 1.0, for the oils of B. dracunculifolia and B. uncinella respectively. The evaluations in gas chromatography coupled to mass spectrophotometry showed that the oils studied are similar, presenting 26 constituents among which β-pinene, ε-nerolidol, limonene and spathulenol are highlighted.

Folhas de diversas espécies de Passiflora são amplamente empregadas na medicina popular brasileira como ansiolítica e sedativa. Neste trabalho, as propriedades ansiolíticas e sedativas e análise por cromatografia líquida dos extratos metanólicos de Passiflora actinia foram avaliados. O extrato metanólico e todas as suas frações apresentaram efeitos sedativos significativos nos testes de labirinto em cruz elevada e campo aberto. Somente a fração aquosa do extrato metanólico mostrou seletiva atividade sedativa (30 mg/kg). Análise cromatográfica das frações ativas mostraram a presença de isovitexina e ausência dos alcalóides beta-carbolínicos clássicos de Passiflora ou flavonóides como vitexina, rutina, swertisina, hesperidina e orientina. A tintura obtida de P. actinia (folhas) apresentou 0,27 mg/ml de isovitexina e ausência de vitexina.

Leaves from several Passiflora species are largely employed in the Brazilian folk medicine as anxiolytic and sedative. In this work the anxiolytic, sedative-like properties and liquid chromatography analysis of methanolic extract of Passiflora actinia were evaluated. The methanol extract and all of its fractions presented significant sedative-like effect in elevated plus-maze and open field tests. Only the aqueous fraction of the methanol extract showed selective anxiolytic activity (30 mg/kg). Chromatographic analysis of the active fractions showed the presence of isovitexin and absence of the classical Passiflora beta-carboline alkaloids or flavonoids such as vitexin, rutin, swertisin, hesperidin and orientin. The tincture obtained from P. actinia leaves presented 0.27 mg/ml of isovitexin and absence of vitexin.