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ABSTRACT The objective of this study is to present the protocol of a cluster randomized clinical trial to be conducted through the TeleICU project - Qualification of Intensive Care by Telemedicine. The study will consist of a cluster randomized clinical trial, open label, in pediatric intensive care units, with an allocation ratio of 1:1, to compare the intervention group (support of Telemedicine for patients admitted to the pediatric intensive care unit) with a control group (pediatric intensive care unit usual care). The study proposed to select 16 pediatric intensive care units, including 100 participants per site, with a total of 1,600 participants. The intervention group will receive telerounds from Monday to Friday and will have specialists and continuing education activities available. The primary outcome measure will be the length of stay in the pediatric intensive care unit, defined as the difference between the date of discharge of the participant and the date of admission to the intensive care unit. The secondary outcomes will be mortality rate, invasive mechanical ventilation-free days, days using antibiotics, days using vasoactive drugs and days using sedoanalgesia. This study will be conducted in accordance with Resolution 466/12 of the National Health Council, with approval by the Research Ethics Committee of the institutions involved. The present study has the potential to reproduce studies on Telemedicine in intensive care and may make important contributions to care in intensive care units in Brazil and other settings. If Telemedicine shows positive clinical care results compared to conventional treatment, more pediatric patients may benefit. ClinicalTrials.gov registry: NCT05260710

RESUMO O objetivo deste estudo será apresentar o protocolo de um ensaio clínico randomizado em cluster a ser realizado por meio do projeto TeleUTI - Qualificação da Assistência em Terapia Intensiva por Telemedicina. O estudo consistirá em um ensaio clínico randomizado por cluster, open label, em unidades de terapia intensiva pediátricas, com proporção de alocação de 1:1, com o intuito de comparar o grupo de intervenção (apoio da telemedicina para os pacientes internados na unidade de terapia intensiva pediátrica) com um grupo controle (cuidados habituais da unidade de terapia intensiva pediátrica). O estudo se propõe a selecionar 16 unidades de terapia intensiva pediátricas, incluindo 100 participantes por local, com o total de 1.600 participantes. O grupo intervenção receberá telerounds de segunda-feira a sexta-feira e terá à disposição especialistas e atividades de educação continuada. O desfecho primário a ser avaliado será o tempo de permanência nas unidades de terapia intensiva pediátricas, definido pela diferença entre a data de alta do participante com a data de admissão na unidade de terapia intensiva. Os desfechos secundários serão: taxa de mortalidade; dias livres de ventilação mecânica, dias de uso de antibióticos, dias de uso de drogas vasoativas e dias de uso de sedoanalgesia. Este estudo será conduzido em conformidade com a resolução 466/12 do Conselho Nacional de Saúde, com aprovação pelo Comitê de Ética em Pesquisa das instituições hospitalares envolvidas. O trabalho tem o potencial de reproduzir estudos sobre Telemedicina em cuidados intensivos, podendo trazer contribuições importantes ao atendimento em unidades de terapia intensiva no Brasil e em outras realidades. Se a Telemedicina mostrar resultados clínicos assistenciais positivos em relação ao tratamento convencional, mais pacientes pediátricos poderão ser beneficiados. Registro ClinicalTrials.gov: NCT05260710

https://doi.org/10.5935/2965-2774.20230223-en

Mobilidade e refúgio no MERCOSUL: a compatibilidade entre a política migratória regional e o direito internacional dos refugiados
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Vieira, Luciane Klein

; Rosa, Marina de Almeida

Revista de la Secretaría del Tribunal Permanente de Revisión

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2023, Volume 11 N. 20 elocation e494

Resumo: O presente artigo procura compreender em que medida a evolução do tratamento da temática migratória, conferida pelo MERCOSUL, se revela adequada aos parâmetros estabelecidos, nos âmbitos regional e universal, pelo direito internacional dos refugiados. Para tanto, examina as bases fundamentais do MERCOSUL, as características e o estado de implementação dos mecanismos regionais de mobilidade e regularização migratória, bem como os standards regional e universal. A pesquisa que se propõe é qualitativa, de cunho exploratório. Para o seu desenvolvimento, utilizar-se-á o método de análise normativo-descritivo, sendo a técnica de pesquisa bibliográfica e documental.

Abstract: This paper tries to understand in which way the evolution of the treatment of the migratory issue, given by the MERCOSUR, is adequate to the parameters established, in the regional and universal scope, by the international refugee law. Therefore, it examines the fundamental bases of MERCOSUR, the characteristics, and the state of implementation of the regional mechanisms of mobility and immigration regulation, as well as the regional and universal standards. The proposed research is qualitative and exploratory. For its development, the normative-descriptive method of analysis will be used, being the technique of bibliographic and documentary research.

Resumen: Este trabajo intenta comprender en qué medida la evolución del tema de las migraciones, en el ámbito del MERCOSUR, es adecuada a los parámetros establecidos por el derecho internacional de los refugiados a nivel regional y universal. Para lograrlo, examina las bases fundamentales del MERCOSUR, sus características y la situación de la implementación de los mecanismos regionales de movilidad humana y regularización migratoria, así como los estándares regionales y universal. La investigación que se propone es cualitativa y exploratoria. Para su desarrollo, será utilizado el método de análisis normativo-descriptivo, siendo la técnica de investigación de cuño bibliográfico y documental.

Résumé: Cet article cherche à comprendre comment l’évolution du traitement de la thématique migratoire, conférée par le MERCOSUR, s’avère adéquate aux paramètres établis, dans les cadres régional et universel, par le droit international des réfugiés. A cette fin, il examine les bases fondamentales du MERCOSUR, les caractéristiques et l’état de mise en œuvre des mécanismes régionaux de mobilité et de régularisation migratoire, ainsi que les normes régionales et universelles. La recherche proposée est qualitative et exploratoire. Pour son développement, la méthode d’analyse normative-descriptive sera utilisée, étant la technique de la recherche bibliographique et documentaire.

https://doi.org/10.16890/rstpr.a11.n20.e494

Comparative Anatomy of Ilex paraguariensis "Erva-Mate" and its Adulterant Citronella gongonha "Falso-Mate”
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Antunes, Kevin Alves

; Monteiro, Luciane Mendes

; Almeida, Valter Paes de

; Baldiserra, Luan Junior

; Raman, Vijayasankar

; Manfron, Jane

Brazilian Archives of Biology and Technology

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2023, Volume 66 N. spe elocation e23230040

Abstract: En | Text: En | PDF: En

Abstract Ilex paraguariensis (Aquifoliaceae), commonly known as “yerba mate” or “erva-mate”, is a shrub or tree native to South America. The leaves of the plant are traditionally used to prepare a caffeine-rich infusion with several medicinal properties, including antirheumatic, antithrombotic, anti-inflammatory, anti-obesity, diuretic, and hypocholesterolemic. Ilex paraguariensis is adulterated with several other species of Ilex, such as I. brevicuspis, I. dumosa, and I. theezans. It is also commonly adulterated with unrelated species, such as Citronella gongonha of Cardiopteridaceae. The latter species, commonly called “false-mate”, is one of the most frequent adulterants due to its similar habit and leaf morphology. Comprehensive studies on authentication and quality control of erva-mate are still scarce. This study provides a detailed comparative anatomy of the leaves and stems of I. paraguariensis and C. gongonha by light and scanning electron microscopy. The main distinguishing characteristics are the epidermal cell wall shape, type of stomata, crystal morphotypes, stem shape, presence or absence of glandular trichomes, and sclerenchymatous sheath. This data can help in the authentication and quality control of erva-mate raw materials.

https://doi.org/10.1590/1678-4324-ssbfar-2023230040

Lesão Miocárdica e Prognóstico em Pacientes Hospitalizados com COVID-19 no Brasil: Resultados do Registro Nacional de COVID-19
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Barbosa, Hannah Cardoso

; Martins, Maria Auxiliadora Parreiras

; Jesus, Jordana Cristina de

; Meira, Karina Cardoso

; Passaglia, Luiz Guilherme

; Sacioto, Manuela Furtado

; Bezerra, Adriana Falangola Benjamin

; Schwarzbold, Alexandre Vargas

; Maurílio, Amanda de Oliveira

; Farace, Barbara Lopes

; Silva, Carla Thais Cândida Alves da

; Cimini, Christiane Corrêa Rodrigues

; Silveira, Daniel Vitorio

; Carazai, Daniela do Reis

; Ponce, Daniela

; Costa, Emanuel Victor Alves

; Manenti, Euler Roberto Fernandes

; Cenci, Evelin Paola de Almeida

; Bartolazzi, Frederico

; Madeira, Glícia Cristina de Castro

; Nascimento, Guilherme Fagundes

; Velloso, Isabela Vasconcellos Pires

; Batista, Joanna d’Arc Lyra

; Morais, Júlia Drumond Parreiras de

; Carvalho, Juliana da Silva Nogueira

; Ruschel, Karen Brasil

; Martins, Karina Paula Medeiros Prado

; Zandoná, Liege Barella

; Menezes, Luanna Silva Monteiro

; Kopittke, Luciane

; Castro, Luís César de

; Nasi, Luiz Antônio

; Floriani, Maiara Anschau

; Souza, Maíra Dias

; Carneiro, Marcelo

; Bicalho, Maria Aparecida Camargos

; Lima, Maria Clara Pontello Barbosa

; Godoy, Mariana Frizzo de

; Guimarães-Júnior, Milton Henriques

; Mendes, Paulo Mascarenhas

; Delfino-Pereira, Polianna

; Ribeiro, Raquel Jaqueline Eder

; Finger, Renan Goulart

; Menezes, Rochele Mosmann

; Francisco, Saionara Cristina

; Araújo, Silvia Ferreira

; Oliveira, Talita Fischer

; Oliveira, Thainara Conceição de

; Polanczyk, Carisi Anne

; Marcolino, Milena Soriano

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 2 elocation e20220151

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Cardiovascular complications of COVID-19 are important aspects of the disease’s pathogenesis and prognosis. Evidence on the prognostic role of troponin and myocardial injury in Latin American hospitalized COVID-19 patients is still scarce. Objectives To evaluate myocardial injury as independent predictor of in-hospital mortality and invasive mechanical ventilation support in hospitalized patients, from the Brazilian COVID-19 Registry. Methods This cohort study is a substudy of the Brazilian COVID-19 Registry, conducted in 31 Brazilian hospitals of 17 cities, March-September 2020. Primary outcomes included in-hospital mortality and invasive mechanical ventilation support. Models for the primary outcomes were estimated by Poisson regression with robust variance, with statistical significance of p<0.05. Results Of 2,925 patients (median age of 60 years [48-71], 57.1% men), 27.3% presented myocardial injury. The proportion of patients with comorbidities was higher among patients with cardiac injury (median 2 [1-2] vs. 1 [0-2]). Patients with myocardial injury had higher median levels of brain natriuretic peptide, lactate dehydrogenase, creatine phosphokinase, N-terminal pro-brain natriuretic peptide, and C-reactive protein than patients without myocardial injury. As independent predictors, C-reactive protein and platelet counts were related to the risk of death, and neutrophils and platelet counts were related to the risk of invasive mechanical ventilation support. Patients with high troponin levels presented a higher risk of death (RR 2.03, 95% CI 1.60-2.58) and invasive mechanical ventilation support (RR 1.87, 95% CI 1.57-2.23), when compared to those with normal troponin levels. Conclusion Cardiac injury was an independent predictor of in-hospital mortality and the need for invasive mechanical ventilation support in hospitalized COVID-19 patients.

Resumo Fundamento As complicações cardiovasculares da COVID-19 são aspectos importantes da patogênese e do prognóstico da doença. Evidências do papel prognóstico da troponina e da lesão miocárdica em pacientes hospitalizados com COVID-19 na América Latina são ainda escassos. Objetivos Avaliar a lesão miocárdica como preditor independente de mortalidade hospitalar e suporte ventilatório mecânico em pacientes hospitalizados, do registro brasileiro de COVID-19. Métodos Este estudo coorte é um subestudo do registro brasileiro de COVID-19, conduzido em 31 hospitais brasileiros de 17 cidades, de março a setembro de 2020. Os desfechos primários incluíram mortalidade hospitalar e suporte ventilatório mecânico invasivo. Os modelos para os desfechos primários foram estimados por regressão de Poisson com variância robusta, com significância estatística de p<0,05. Resultados Dos 2925 pacientes [idade mediana de 60 anos (48-71), 57,1%], 27,3% apresentaram lesão miocárdica. A proporção de pacientes com comorbidades foi maior nos pacientes com lesão miocárdica [mediana 2 (1-2) vs. 1 (0-20)]. Os pacientes com lesão miocárdica apresentaram maiores valores medianos de peptídeo natriurético cerebral, lactato desidrogenase, creatina fosfoquinase, N-terminal do pró-peptídeo natriurético tipo B e proteína C reativa em comparação a pacientes sem lesão miocárdica. Como fatores independentes, proteína C reativa e contagem de plaquetas foram relacionados com o risco de morte, e neutrófilos e contagem de plaquetas foram relacionados ao risco de suporte ventilatório mecânico invasivo. Os pacientes com níveis elevados de troponina apresentaram um maior risco de morte (RR 2,03, IC95% 1,60-2,58) e suporte ventilatório mecânico (RR 1,87;IC95% 1,57-2,23), em comparação àqueles com níveis de troponina normais. Conclusão Lesão cardíaca foi um preditor independente de mortalidade hospitalar e necessidade de suporte ventilatório mecânico em pacientes hospitalizados com COVID-19.

https://doi.org/10.36660/abc.20220151

Cyberbullying and Motivation to Learn with Digital Technologies: Identification and Correlation
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Beluce, Andrea Carvalho

; Oliveira, Katya Luciane de

; Ferraz, Adriana Satico

; Almeida, Leandro da Silva

Psicologia: Teoria e Pesquisa

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2023, Volume 39 N. spe elocation e39nspe07

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This article investigates the relationship of cyberbullying to motivation to learn and the use of digital information and communication technologies (DTIC). The survey included 529 high school and 293 higher education students who answered the Motivation to Learn Scale with the use of DITC Scale and the Cyberbullying Assessment Scale. Statistically significant correlations were identified between the constructs, especially in high school. The relationships had a positive direction, weak and high magnitude. Cyberbullying and educational levels predicted controlled (28%) and autonomous (5%) motivation. Motivation and cyberbullying levels stood out in high school. This research contributes to pedagogical practices and the conduct of further studies on this theme.

Resumo Neste artigo investigaram-se as relações do cyberbullying para a motivação para aprender e o uso de tecnologias digitais de informação e comunicação (TDIC). Participaram da pesquisa 529 alunos do ensino médio e 293 do ensino superior que responderam a Escala de Motivação para Aprender com o uso das TDIC e a Escala de Avaliação do Cyberbullying. Identificaram-se correlações estatisticamente significativas entre os construtos, sobretudo no ensino médio. As relações tiveram uma direção positiva, de fraca e alta magnitude. O cyberbullying e os níveis de ensino predisseram a motivação controlada (28%) e autônoma (5%). Os níveis de motivação e cyberbullying se sobressaíram no ensino médio. Esta pesquisa contribui para as práticas pedagógicas e a condução de novos estudos sobre esta temática.

https://doi.org/10.1590/0102.3772e39nspe07.en

Minor psychiatric disorders among university students during the COVID-19 pandemic
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Kantorski, Luciane Prado

; Guedes, Ariane da Cruz

; Brum, Aline Neutzling

; Treichel, Carlos Alberto dos Santos

; Santos, Vinícius Boldt dos

; Gonçalves, Bianca Albuquerque

; Almeida, Mariana Dias

Revista Gaúcha de Enfermagem

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2023, Volume 44 elocation e20220064

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: To identify the prevalence and factors associated with the manifestation of Minor Psychiatric Disorders (MPD) among university students in southern Brazil during the COVID-19 pandemic. Method: Cross-sectional study, conducted in August and September 2020, with 464 university students. The Self-Reporting Questionnaire (SRQ-20) was used with a cut-off point ≥ 7, and associated factors were identified through crude and adjusted analyses using logistic regression. Results: The prevalence of MPD was 76.5%. Factors positively associated with the outcome were female gender, job loss during the pandemic, use of psychoactive substances, and difficulties in following online classes. Being in social distancing for seven months or more was negatively associated with the outcome. Conclusion: High prevalence of MPD among the studied sample, as well as a relationship between this outcome and the consequences of the COVID-19 pandemic.

RESUMEN Objetivo: Identificar la prevalencia y los factores asociados a la manifestación de trastornos psiquiátricos menores en estudiantes universitarios del sur de Brasil durante la pandemia del COVID-19. Método: Estudio realizado en 2020, con 464 alumnos vinculados a una disciplina optativa de Salud Mental. Para el resultado se utilizó el Self-Reporting Questionnaire (SRQ-20), con el punto de corte ≥ 7. La identificación de los factores asociados se realizó mediante regresión logística, precedida de selección de factores de confusión. Resultados: Prevalencia de trastornos psiquiátricos menores correspondiente al 76,5% entre los participantes. Factores asociados positivamente con este resultado: sexo femenino, la pérdida de empleo durante la pandemia, el consumo de sustancias psicoactivas y las dificultades para seguir las clases en línea. Estar socialmente distante durante siete meses o más se asoció negativamente con el resultado. Conclusión: Alta prevalencia de malestar emocional entre la muestra, así como una relación entre este resultado y la pandemia.

RESUMO Objetivo: Identificar a prevalência e os fatores associados à manifestação de Transtornos Psiquiátricos Menores (TPM) em estudantes universitários do Sul do Brasil durante a pandemia da COVID-19. Método: Estudo transversal, realizado nos meses de agosto e setembro de 2020, com 464 estudantes universitários. Foi utilizado o Self-Reporting Questionnaire (SRQ-20) com o ponto de corte ≥ 7, e identificados os fatores associados por meio de análises brutas e ajustadas com emprego de regressão logística. Resultados: A prevalência de TPM foi de 76,5%. Os fatores positivamente associados ao desfecho foram as pessoas do sexo feminino, perda de emprego durante a pandemia, uso de substâncias psicoativas e dificuldades para acompanhar as aulas on-line. Esteve negativamente associado ao desfecho, estar em distanciamento social por período igual ou superior a sete meses. Conclusão: O estudo sugere alta prevalência de TPM entre os universitários e a relação entre esse desfecho e os desdobramentos da pandemia da COVID-19.

https://doi.org/10.1590/1983-1447.2023.20220064.en

The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal
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Lamas, Carlos José Einicker

; Fachin, Diego Aguilar

; Falaschi, Rafaela Lopes

; Alcantara, Daniel Máximo Correa de

; Ale-Rocha, Rosaly

; Amorim, Dalton de Souza

; Araújo, Maíra Xavier

; Ascendino, Sharlene

; Baldassio, Letícia

; Bellodi, Carolina Ferraz

; Bravo, Freddy

; Calhau, Julia

; Capellari, Renato Soares

; Carmo-Neto, Antonio Marcelino do

; Cegolin, Bianca Melo

; Couri, Márcia Souto

; Carvalho, Claudio José Barros de

; Dios, Rodrigo de Vilhena Perez

; Falcon, Aida Vanessa Gomez

; Fusari, Livia Maria

; Garcia, Carolina de Almeida

; Gil-Azevedo, Leonardo Henrique

; Gomes, Marina Morim

; Graciolli, Gustavo

; Gudin, Filipe Macedo

; Henriques, Augusto Loureiro

; Krolow, Tiago Kütter

; Mendes, Luanna Layla

; Limeira-de-Oliveira, Francisco

; Maia, Valéria Cid

; Marinoni, Luciane

; Mello, Ramon Luciano

; Mello-Patiu, Cátia Antunes de

; Morales, Mírian Nunes

; Oliveira, Sarah Siqueira

; Patiu, Claudemir

; Proença, Barbara

; Pujol-Luz, Cristiane Vieira de Assis

; Pujol-Luz, José Roberto

; Rafael, José Albertino

; Riccardi, Paula Raile

; Rodrigues, João Paulo Vinicios

; Roque, Fabio de Oliveira

; Sallum, Maria Anice Mureb

; Santis, Marcelo Domingos de

; Santos, Charles Morphy Dias dos

; Santos, Josenilson Rodrigues dos

; Savaris, Marcoandre

; Shimabukuro, Paloma Helena Fernandes

; Silva, Vera Cristina

; Schelesky-Prado, Daniel de Castro

; Silva-Neto, Alberto Moreira da

; Camargo, Alexssandro

; Sousa, Viviane Rodrigues de

; Urso-Guimarães, Maria Virginia

; Wiedenbrug, Sofia

; Yamaguchi, Carolina

; Nihei, Silvio Shigueo

Revista Brasileira de Entomologia

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2023, Volume 67 N. 4 elocation e20230051

Abstract: En | Text: En | PDF: En

ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists.

https://doi.org/10.1590/1806-9665-rbent-2023-0051

Confirmatory factor analysis of Intellectual Styles Inventory – Revised 2: High School Sample
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Oliveira, Katya Luciane de

; Inácio, Amanda Lays Monteiro

; Almeida, Leandro da Silva

; Santos, Acácia Aparecia Angeli dos

; Martins, Gustavo Henrique

; Oliveira, Gracielly Terziotti de

Estudos de Psicologia (Campinas)

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2023, Volume 40 elocation e200097

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective: This study aimed to test, using the Confirmatory Factor Analysis model, the factor structure proposed in the Intellectual Styles Inventory – Revised 2. Methods: The study involved the participation of 1,556 High School students with a mean age of 16 years and 4 months (SD = 1.17). Results: Confirmatory Factor Analysis was used and the model was based on the structure of 46 items distributed in nine dimensions, having demonstrated good rates of fit and accuracy. It was verified that the model originally indicated by the scientific literature was not confirmed in the Brazilian context, being proposed modifications that bring the current model closer to the national reality. Conclusion: There was an adjustment in the estimates of the parameters used, and stability and generality can be considered in the way the model was organized.

Resumo Objetivo: Este estudo teve por objetivo testar, por meio do modelo da Análise Fatorial Confirmatória, a estrutura fatorial proposta no Inventário de Estilos Intelectuais – Revisado 2. Método: O estudo envolveu a participação de 1.556 alunos do Ensino Médio, com média de idade de 16 anos e 4 meses (DP = 1,17). Resultados: A Análise Fatorial Confirmatória foi empregada e o modelo foi baseado na estrutura de 46 itens distribuídos em nove dimensões, tendo demonstrado bons índices de ajustes e de precisão. Verificou-se que o modelo indicado originalmente pela literatura científica não se confirmou no contexto brasileiro, sendo propostas modificações que aproximem o modelo vigente da realidade nacional. Conclusão: Houve uma adequação nas estimativas dos parâmetros empregados, podendo-se considerar estabilidade e generabilidade na forma como o modelo ficou organizado.

https://doi.org/10.1590/1982-0275202340e200097

DIÁLOGO SOBRE DOAÇÃO DE ÓRGÃOS E TECIDOS: GAMIFICATION NA EDUCAÇÃO PERMANENTE EM SAÚDE
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Lima, Lucas Vinícius de

; Pavinati, Gabriel

; Gonçalves, Luciane de Assis Rocha

; Corsi, Carlos Alexandre Curylofo

; Cabianchi, Ellen Catarine

; Freitas, Rosane Almeida de

; Baldissera, Vanessa Denardi Antoniassi

Cogitare Enfermagem

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2023, Volume 28 elocation e86384

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: to systematize the teaching-service partnership experience in the creation and application of a virtual game on organ and tissue donation as a proposal for permanent education in health. Method: systematization of an experience, conducted through documentary analysis, involving the process to create and apply an educational gamification practice by Nursing students, professors and professionals who developed the strategy and applied it at a university hospital in southern Brazil in September 2020. Results: given the health context imposed by COVID-19, the virtual game consisting of 20 questions about the organ and tissue donation process for transplants, as a strategy for ongoing health education, inspired engagement and motivation among the professionals, who showed limited knowledge about the theme and evaluated the strategy as positive. Conclusion: a potential path to be replicated in different contexts and scenarios was made evident, stimulating and encouraging the care and education processes.

RESUMEN Objetivo: sistematizar la experiencia de la asociación entre enseñanza y servicio en la creación y aplicación de un juego virtual sobre donación de órganos y tejidos en términos de una propuesta de educación permanente para la salud. Método: sistematización de la experiencia, dirigida por análisis documental y abarcando el proceso de elaboración y aplicación de una práctica educativa de gamificación por parte de estudiantes, profesores y profesionales de Enfermería, que desarrollaron la estrategia y la aplicaron en un hospital universitario del sur de Brasil en septiembre de 2020. Resultados: frente al contexto sanitario impuesto por la COVID-19, en términos de estrategia de educación permanente para la salud, el juego virtual compuesto por 20 preguntas sobre el proceso de donación de órganos y tejidos para trasplantes inspiró compromiso y motivación en los profesionales, quienes demostraron escasos conocimientos acerca de la temática y evaluaron la estrategia como positiva. Conclusión: se evidenció un potencial camino a ser replicado en diferentes contextos y temáticas, estimulando y alentando el proceso de la atención y educación en salud.

RESUMO Objetivo: sistematizar a experiência da parceria ensino-serviço na elaboração e aplicação de um jogo virtual sobre doação de órgãos e tecidos enquanto proposta de educação permanente em saúde. Método: sistematização de experiência, conduzida por análise documental, envolvendo o processo de elaboração e aplicação de uma prática educativa de gamification por estudantes, professores e profissionais da enfermagem, que desenvolveram a estratégia e aplicaram em um hospital universitário no Sul do Brasil em setembro de 2020. Resultados: ante o contexto sanitário imposto pela covid-19, o jogo virtual composto por 20 questões em torno do processo de doação de órgãos e tecidos para transplantes, enquanto estratégia de educação permanente em saúde, inspirou engajamento e motivação dos profissionais, que mostraram escasso conhecimento acerca da temática e avaliaram a estratégia como positiva. Conclusão: evidenciou-se um caminho potencial a ser replicado em diferentes contextos e temáticas, estimulando e encorajando o processo de cuidado e de educação.

https://doi.org/10.1590/ce.v28i0.86384

10.

Macroporous latex biomembrane from Hancornia speciosa modulates the inflammatory process and has a debridement effect on wound healing in rats
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Martins, Kassya Lopes Epaminondas

; Thomaz, Marcelo Martins

; Magno, Lais Nogueira

; Vinaud, Marina Clare

; Almeida, Luciane Madureira

; Gonçalves, Pablo José

; Lino Junior, Ruy de Souza

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e385323

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: The angiogenic, osteogenic and anti-inflammatory activity of latex of Hancornia speciosa has been evidenced and indicates pharmacological potential with great applicability in the health area, especially in the wound healing process. The present work aimed to compare the effects of the H. speciosa macroporous latex biomembrane with saline on wound healing. Methods: Forty-three Wistar rats were submitted to excisional wound induction procedure and divided into groups according to treatment: saline (G1), and macroporous biomembrane (G2). The animals were euthanized at three, seven, 14, and 21 days after injury induction (DAI), and three animals were used for the debridement test. Morphometric, macroscopic, and microscopic analyses of general pathological processes were performed. Results: The macroporous biomembrane minimized necrosis and inflammation during the inflammatory and proliferative phases of the healing process, confirmed by the lower intensity of the crust and the debridement effect. In addition, the wounds treated with the macroporous biomembrane presented greater contraction rates in all the experimental periods analyzed. Conclusions: The macroporous biomembrane presents angiogenic, anti-inflammatory and debridement effects, contributing to the healing process, and can be considered a potentially promising new biomaterial to be used as a dressing.

https://doi.org/10.1590/acb385323

11.

Pigmented eccrine poroma in an atypical location
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Alfredo, Melissa de Almeida Corrêa

; Lai, Mariana Righetto de Ré

; Miot, Luciane Donida Bartoli

; Haddad, Gabriela Roncada

; Garcia, Aline Lutz

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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oct 2022, Volume 97 N. 5 Pages 624 - 627

Abstract: En | Text: En | PDF: En

Abstract Eccrine poroma is the term that includes benign neoplasms of the terminal duct of the eccrine sweat glands, which may clinically and dermoscopically resemble other melanoma and non-melanoma skin tumors. They are often located on the extremities (especially palms and soles), presenting as normochromic or erythematous papules and nodules, measuring up to 2 cm. Pigmented variants are uncommon, accounting for less than 20% of cases. This report describes a 37-year-old man who developed a large pigmented eccrine poroma on his right shoulder, causing diagnostic difficulty. Histopathological examination revealed a nodular neoplasm consisting of small, monomorphic, cuboidal cells, with ample, eosinophilic cytoplasm and well-defined borders, in addition to conspicuous intercellular bridges, with melanin deposits diffusely distributed inside them. The absence of cytological atypia, cellular pleomorphism, increased mitotic activity, and necrosis foci corroborated the diagnostic exclusion of porocarcinoma, which can develop from eccrine poroma.

https://doi.org/10.1016/j.abd.2021.10.006

12.

Management Strategies for Sexuality Complaints after Gynecologic Cancer: A Systematic Review
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Pizetta, Luciane Machado

; Reis, Augusto da Cunha

; Méxas, Mirian Picinini

; Guimarães, Vanessa de Almeida

; de Paula, Carmen Lucia

Revista Brasileira de Ginecologia e Obstetrícia

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oct 2022, Volume 44 N. 10 Pages 962 - 971

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective To explore the main sexuality complaints of gynecologic cancer survivors after treatment and to identify the care strategies provided. Data Source Searches were conducted in six electronic databases: Scopus, Web of Science, LILACS, MEDLINE, PsychINFO, and EMBASE. Study Selection Articles published between 2010 and 2020 were selected and the following descriptors were used in the English language: female genital neoplasms and gynaecological cancer. The methodological quality of the studies used the Mixed Methods Appraisal Tool (MMAT). Data Collection The primary data extracted were: names of the authors, year of publication, country of origin, objective and type of study, data collection instrument, sample size and age range, types of cancer, and symptoms affected with the strategies adopted. Data Summary A total of 34 out of 2,536 screened articles were included. The main strategies found for patient care were patient-clinician communication, practices for sexuality care, individualized care plan, multiprofessional team support, and development of rehabilitation programs. For sexuality care, the most common practices are pelvic physiotherapy sessions and the use of vaginal gels and moisturizers. Conclusion The main complaints identified in the scientific literature were low libido and lack of interest in sexual activity, vaginal dryness, pain during sexual intercourse, and stenosis. Different care strategies may be adopted, such as follow-up with a multidisciplinary health team and sexual health rehabilitation programs, which could minimize these symptoms and ensure the quality of life of patients.

Resumo Objetivo Explorar as principais queixas da sexualidade com sobreviventes de câncer ginecológico após o tratamento e identificar as estratégias de cuidados prestados. Fonte dos Dados As buscas foram realizadas em seis bases eletrônicas: Scopus, Web of Science, LILACS, MEDLINE, PsychINFO e EMBASE. Seleção dos Estudos Foram selecionados artigos publicados entre 2010 e 2020 e os descritores utilizados (em inglês) foram female genital neoplasms e gynaecological cancer. A qualidade metodológica dos estudos utilizou a ferramenta Mixed Methods Appraisal Tool (MMAT). Coleta de Dados Os principais dados extraídos foram: nomes dos autores, ano de publicação, país de origem, objetivo e tipo de estudo, instrumento para coleta de dados, tamanho da amostra e faixa etária, tipos de câncer, os sintomas acometidos e as estratégias adotadas. Síntese dos Dados Dos 2,536 artigos identificados, 34 foram incluídos. As principais estratégias encontradas para os cuidados aos pacientes foram a comunicação paciente-médico, práticas para os cuidados sexuais, plano de cuidados individualizado, apoio a equipes multiprofissionais e desenvolvimento de programas de reabilitação. Para os cuidados de sexualidade, as práticas mais comuns são sessões de fisioterapia pélvica e o uso de géis vaginais e hidratantes. Conclusão As principais queixas identificadas na literatura científica foram baixa libido e falta de interesse na atividade sexual, secura vaginal, dor durante a relação sexual e estenose. Diferentes estratégias de cuidados podem ser adotadas, como o acompanhamento com uma equipe de saúde multidisciplinar e programas de reabilitação da saúde sexual, as quais poderiam minimizar estes sintomas e garantir a qualidade de vida dos pacientes.

https://doi.org/10.1055/s-0042-1756312

13.

Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
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Sartor, Ivaine Tais Sauthier

; David, Caroline Nespolo de

; Telo, Gabriela Heiden

; Zavaglia, Gabriela Oliveira

; Fernandes, Ingrid Rodrigues

; Kern, Luciane Beatriz

; Polese-Bonatto, Márcia

; Azevedo, Thaís Raupp

; Santos, Amanda Paz

; Almeida, Walquiria Aparecida Ferreira de

; Porto, Victor Bertollo Gomes

; Varela, Fernanda Hammes

; Scotta, Marcelo Comerlato

; Rosa, Regis Goulart

; Stein, Renato T.

Archives of Endocrinology and Metabolism

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aug 2022, Volume 66 N. 4 Pages 512 - 521

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.

https://doi.org/10.20945/2359-3997000000486

14.

Brazilian practice guidelines for stroke rehabilitation: part II
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Minelli, Cesar

; Luvizutto, Gustavo José

; Cacho, Roberta de Oliveira

; Neves, Luciana de Oliveira

; Magalhães, Sheila Cristina Sayuri Abe

; Pedatella, Marco Túlio Araújo

; Mendonça, Lucia Iracema Zanotto de

; Ortiz, Karin Zazo

; Lange, Marcos Christiano

; Ribeiro, Priscila Watson

; Souza, Luciane Aparecida Pascucci Sande de

; Milani, Cristiano

; Cruz, Daniel Marinho Cezar da

; Costa, Rafael Dalle Molle da

; Conforto, Adriana Bastos

; Carvalho, Fernanda Martins Maia

; Ciarlini, Bruna Silva

; Frota, Norberto Anizio Ferreira

; Almeida, Kelson James

; Schochat, Eliane

; Oliveira, Tatiana de Paula

; Miranda, Camila

; Piemonte, Maria Elisa Pimentel

; Lopes, Laura Cardia Gomes

; Lopes, Camila Galvão

; Tosin, Michelle Hyczy de Siqueira

; Oliveira, Bianca Campos

; Oliveira, Beatriz Guitton Renaud Baptista de

; Castro, Shamyr Sulyvan de

; Andrade, João Brainier Clares de

; Silva, Gisele Sampaio

; Pontes-Neto, Octávio Marques

; Carvalho, João José Freitas de

; Martins, Sheila C. Ouriques

; Bazan, Rodrigo

Arquivos de Neuro-Psiquiatria

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jul 2022, Volume 80 N. 7 Pages 741 - 758

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The Brazilian Practice Guidelines for Stroke Rehabilitation – Part II, developed by the Scientific Department of Neurological Rehabilitation of the Brazilian Academy of Neurology (Academia Brasileira de Neurologia, in Portuguese), focuses on specific rehabilitation techniques to aid recovery from impairment and disability after stroke. As in Part I, Part II is also based on recently available evidence from randomized controlled trials, systematic reviews, meta-analyses, and other guidelines. Part II covers disorders of communication, dysphagia, postural control and balance, ataxias, spasticity, upper limb rehabilitation, gait, cognition, unilateral spatial neglect, sensory impairments, home rehabilitation, medication adherence, palliative care, cerebrovascular events related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the future of stroke rehabilitation, and stroke websites to support patients and caregivers. Our goal is to provide health professionals with more recent knowledge and recommendations for better rehabilitation care after stroke.

Resumo As Diretrizes Brasileiras de Reabilitação do Acidente Vascular Cerebral (AVC) - Parte II, desenvolvida pelo Departamento Científico de Reabilitação Neurológica da Academia Brasileira de Neurologia é voltada para intervenções específicas de técnicas de reabilitação de déficits neurológicos e incapacidades. Seguindo o mesmo modelo da Parte I, a Parte II também se baseia em estudos randomizados, revisões sistemáticas, metanálises e outras diretrizes sobre o mesmo tema. A segunda parte aborda os distúrbios da comunicação, disfagia, controle postural e equilíbrio, ataxias, espasticidade, reabilitação do membro superior, marcha, cognição, negligência espacial unilateral, déficits sensoriais, reabilitação domiciliar, aderênciaao usode medicamentos, cuidados paliativos,ofuturodareabilitação no AVC, e websites de orientação sobre AVC para pacientes e cuidadores. Nosso objetivo é fornecer aos profissionais envolvidos na reabilitação conhecimento atualizado e recomendações para um melhor cuidado no pós-AVC.

https://doi.org/10.1055/s-0042-1757692

15.

Low performance of a SARS-CoV-2 point-of-care lateral flow immunoassay in symptomatic children during the pandemic
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Scotta, Marcelo Comerlato

; David, Caroline Nespolo de

; Varela, Fernanda Hammes

; Sartor, Ivaine Tais Sauthier

; Polese-Bonatto, Márcia

; Fernandes, Ingrid Rodrigues

; Zavaglia, Gabriela Oliveira

; Ferreira, Charles Francisco

; Kern, Luciane Beatriz

; Santos, Amanda Paz

; Krauzer, João Ronaldo Mafalda

; Pitrez, Paulo Márcio

; Almeida, Walquiria Aparecida Ferreira de

; Porto, Victor Bertollo Gomes

; Stein, Renato T.

Jornal de Pediatria

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apr 2022, Volume 98 N. 2 Pages 136 - 141

Abstract: En | Text: En | PDF: En

Abstract Objective: to evaluate the accuracy of an antibody point-of-care lateral flow immunoassay (LFI -Wondfo Biotech Co., Guangzhou, China) in a pediatric population. Methods: children and adolescents (2 months to 18 years) with signs and symptoms suggestive of acute SARS-CoV-2 infection were prospectively investigated with nasopharyngeal RT-PCR and LFI at the emergency room. RT-PCR was performed at baseline, and LFI at the same time or scheduled for those with less than 7 days of the clinical picture. Overall accuracy, sensitivity and specificity were assessed, as well as according to the onset of symptoms (7-13 or ≥14 days) at the time of the LFI test. Results: In 175 children included, RT-PCR and LFI were positive in 51 (29.14%) and 36 (20.57%), respectively. The overall sensitivity, specificity, positive and negative predictive value was 70.6% (95%CI 56.2-82.5), 96.8% (95%CI 91.9-99.1), 90.0% (95%CI 77.2-96.0), and 88.9% (95%CI 83.9-92.5), respectively. At 7-13 and ≥14 days after the onset of symptoms, sensitivity was 60.0% (95%CI 26.2-87.8) and 73.2% (95%CI 57.1-85.8) and specificity was 97.9% (95%CI 88.7-99.9) and 96.1% (95%CI 89.0-99.2), respectively. Conclusion: Despite its high specificity, in the present study the sensitivity of LFI in children was lower (around 70%) than most reports in adults. Although a positive result is informative, a negative LFI test cannot rule out COVID-19 in children.

https://doi.org/10.1016/j.jped.2021.04.010

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