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Abstract Objective: To assess the diagnostic accuracy of histogram analysis on unenhanced computed tomography (CT) for differentiating between adrenal adenomas and pheochromocytomas (PCCs). Materials and Methods: We retrospectively identified patients with proven PCCs who had undergone CT examinations between January 2009 and July 2019 at one of two institutions. For each PCC, we selected one or two adenomas diagnosed within two weeks of the date of diagnosis of the PCC. For each lesion, two readers scored the size, determined the mean attenuation, and generated a voxel histogram. The 10th percentile (P10) was obtained from the conventional histogram analysis, as well as being calculated with the following formula: P10 = mean attenuation – (1.282 × standard deviation). The mean attenuation threshold, histogram analysis (observed) P10, and calculated P10 (calcP10) were compared in terms of their diagnostic accuracy. Results: We included 52 adenomas and 29 PCCs. The sensitivity, specificity, and accuracy of the mean attenuation threshold were 75.0%, 100.0%, and 82.5%, respectively, for reader 1, whereas they were 71.5%, 100.0%, and 81.5%, respectively, for reader 2. The sensitivity, specificity, and accuracy of the observed P10 and calcP10 were equal for both readers: 90.4%, 96.5%, and 92.6%, respectively, for reader 1; and 92.3%, 93.1%, and 92.6%, respectively, for reader 2. The increase in sensitivity was significant for both readers (p = 0.009 and p = 0.005, respectively). Conclusion: For differentiating between adenomas and PCCs, the histogram analysis (observed P10 and calcP10) appears to outperform the mean attenuation threshold as a diagnostic criterion.

Resumo Objetivo: Avaliar a acurácia diagnóstica da análise por histograma na tomografia computadorizada (TC) sem contraste para a diferenciação entre adenomas adrenais e feocromocitomas (FCCs). Materiais e Métodos: Identificamos, retrospectivamente, pacientes com diagnóstico de FCC confirmado que foram submetidos a exames de TC entre janeiro de 2009 e julho de 2019 em duas instituições distintas. Para cada FCC, selecionamos um ou dois adenomas diagnosticados em até duas semanas da data do diagnóstico do FCC. Para cada lesão, dois leitores pontuaram o tamanho, determinaram a atenuação média e geraram um histograma com os voxels das imagens. O percentil 10 (P10) foi obtido a partir da análise convencional do histograma, além de ser calculado com a seguinte fórmula: P10 = atenuação média - (1,282 × desvio-padrão). O limiar de atenuação média, o P10 da análise por histograma (P10 observado) e o P10 calculado (P10calc) foram comparados em termos de acurácia diagnóstica. Resultados: Foram incluídos 52 adenomas e 29 FCCs. A sensibilidade, especificidade e acurácia do limiar de atenuação média foram de 75,0%, 100,0% e 82,5% para o leitor 1, respectivamente, e de 71,5%, 100,0% e 81,5% para o leitor 2, respectivamente. A sensibilidade, especificidade e acurácia do P10 observado e do P10calc foram idênticas para os dois leitores: 90,4%, 96,5% e 92,6%, respectivamente, para o leitor 1; e 92,3%, 93,1% e 92,6%, respectivamente, para o leitor 2. O aumento da sensibilidade foi significativo para ambos os leitores (p = 0,009 e p = 0,005, respectivamente). Conclusão: Para a diferenciação entre adenomas e FCCs, a análise por histograma (P10 observado ou P10calc) parece superar o limiar de atenuação média como critério diagnóstico.

https://doi.org/10.1590/0100-3984.2022.0067

Vulnerability in adolescents’ daily life during the COVID-19 pandemic
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Ribeiro, Aline Cammarano

; Ianzer, Fabiano Ritta Malagues

; Siqueira, Fernanda Duarte

; Neves, Eliane Tatsch

; Souza, Neila Santini de

; Barreto, Camila Nunes

; Senhem, Graciela Dutra

; Bugs, Cíntia Vanuza Monteiro

Revista da Escola de Enfermagem da USP

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2023, Volume 57 elocation e20230100

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: To know the vulnerability in adolescents’ daily life during the COVID-19 pandemic. Method: Qualitative research carried out with 25 adolescents from a public school in a municipality in southern Brazil in the second half of 2021 through individual semi-structured interviews. Data were submitted to thematic content analysis and interpreted with the vulnerability theoretical framework. Results: These adolescents’ daily lives during the COVID-19 pandemic presented difficulties in keeping family members working, changing habits and routines, accessing classes, the internet and increasing intra-family violence. Conclusion: Vulnerability in adolescents’ daily life during the pandemic can be identified as the absence of interaction in the school context and access to learning resources, reflecting on individual and social vulnerability. Unemployment and possible access to other sources of income have an impact on programmatic vulnerability. Reflection on practices in the context of health and school is suggested, based on the vulnerability identified in adolescents’ daily lives during the COVID-19 pandemic.

RESUMEN Objetivo: Conocer la vulnerabilidad en el cotidiano de los adolescentes ante la pandemia de COVID-19. Método: Investigación cualitativa, realizada con 25 adolescentes de una escuela pública de un municipio del sur de Brasil, en el segundo semestre de 2021, a través de entrevistas semiestructuradas individuales. Los datos fueron sometidos al análisis de contenido temático e interpretados con el referencial teórico de la vulnerabilidad. Resultados: El cotidiano de estos adolescentes durante la pandemia de la COVID-19 presentó dificultades para conservar el trabajo de los familiares, cambio de hábitos y rutinas, acceso a clases, internet y aumento de la violencia intrafamiliar. Conclusión: La vulnerabilidad en el cotidiano de los adolescentes durante la pandemia se puede identificar como la ausencia de interacción en el contexto escolar y acceso a los recursos de aprendizaje, reflexionando sobre la vulnerabilidad individual y social. El desempleo y el posible acceso a otras fuentes de ingresos inciden en la vulnerabilidad programática. Se sugiere la reflexión sobre las prácticas en el contexto de la salud y la escuela, a partir de la vulnerabilidad identificada en el cotidiano de los adolescentes en la pandemia de la COVID-19.

RESUMO Objetivo: Conhecer a vulnerabilidade no cotidiano de adolescentes na pandemia de COVID-19. Método: Pesquisa qualitativa, realizada com 25 adolescentes de uma escola pública em um município do Sul do Brasil, no segundo semestre de 2021, por meio de entrevistas semiestruturadas individuais. Os dados foram submetidos à análise temática de conteúdo e interpretados com o referencial teórico da vulnerabilidade. Resultados: O cotidiano desses adolescentes na pandemia de COVID-19 apresentou-se com dificuldades na manutenção de empregos dos familiares, mudança de hábitos e rotinas, forma de acesso às aulas, internet e aumento da violência intrafamiliar. Conclusão: A vulnerabilidade no cotidiano de adolescentes durante a pandemia pode ser identificada como a ausência do convívio no contexto escolar e acesso aos recursos para aprendizagem, refletindo na vulnerabilidade individual e social. O desemprego e o possível acesso de outras fontes de renda repercutem na vulnerabilidade programática. Sugere-se a reflexão sobre práticas no contexto da saúde e da escola, tendo por base a vulnerabilidade identificada no cotidiano de adolescentes na pandemia de COVID-19.

https://doi.org/10.1590/1980-220x-reeusp-2023-0100en

Spatial variability characterization of acoustic discomfort and zone of admissible noise caused by micro-tractor
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Martins, Fabiano Battermarco da Silva

; Ferraz, Gabriel Araújo e Silva

; Cunha, João Paulo Barreto

; Marin, Diego Bedin

; Santos, Luana Mendes do

; Santana, Lucas Santos

Revista Facultad Nacional de Agronomía Medellín

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aug 2022, Volume 75 N. 2 Pages 9941 - 9949

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN El desarrollo agrícola exige una mayor adopción de maquinaria por parte de los productores para evitar el daño a la salud de los trabajadores por el exceso de ruido. En este escenario, este estudio presenta análisis utilizando geoestadística y Control Estadístico de Procesos (SPC) en el mapeo de la variabilidad espacial de la magnitud del ruido emitido por un microtractor para identificar zonas saludables para los trabajadores. El estudio se llevó a cabo en la Universidad Federal de Lavras (UFLA), donde los niveles de ruido se recolectaron en puntos distribuidos en una cuadrícula de muestra regular de 2,0×2,0 m alrededor de la máquina. La dependencia espacial del ruido se analizó ajustando el semivariograma de tipo onda e interpolando por kriging ordinario y el SPC a través de cartas de control individuales. Fue posible observar valores de ruido superiores a 85 dB(A) en un radio de hasta 6 m alrededor del tractor en funcionamiento. El valor máximo de 91 dB(A) se obtuvo desde el asiento del operador, permitiendo así una exposición diaria máxima de 3,5 h. Además, se observó que las personas ubicadas a distancias mayores a 4 m del microtractor no necesitan usar equipo de protección personal para una exposición de 8 h de trabajo.

ABSTRACT Agricultural development requires greater adoption of machinery by producers to avoid damage to the worker's health due to excessive noise. In this scenario, this study aimed to analyze the noise magnitude emitted by a micro-tractor using geostatistics and Statistical Process Control (SPC) in mapping spatial variability to identify healthy zones for workers. The study was carried out at the Federal University of Lavras (UFLA), where noise levels were collected at points distributed in a regular 2.0×2.0 m sample grid around the machine. The spatial dependence of noise was analyzed by adjusting the wave-type semivariogram and interpolating by ordinary kriging and the SPC through individual control charts. It was possible to observe alarming noise values above 85 dB(A) in a radius of up to 6 m around the tractor in operation. The maximum value of 91 dB(A) was obtained from the operator's seat, thus allowing maximum daily exposure of 3.5 h. In addition, it was observed that people located at distances greater than 4 m from the micro-tractor do not need to wear personal protective equipment for an exposure of 8 h of work.

https://doi.org/10.15446/rfnam.v75n2.96242 36 downloads

Effect of stocking management and nitrogen supplementation on pasture milk yield
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Dias, Rita Kelly Couto Brandão

; Teixeira, Fábio Andrade

; Fries, Daniela Deitos

; Silva, Fabiano Ferreira da

; Dias, Daniel Lucas Santos

; Santos, Jeankarlo Penalva dos

; Barreto, Fernando Oliveira

; Rodrigues, Sinara Sales de Oliveira

; Meneses, Murilo de Almeida

Ciência Animal Brasileira

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2022, Volume 23 elocation e-72333E

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivou-se avaliar os efeitos dos manejos do pastejo ponta e repasse combinados a substituição parcial da proteína do suplemento por nitrogênio ureico sobre o consumo e digestibilidade dos nutrientes, composição do leite e balanço de nitrogênio de vacas primíparas da raça Girolanda. As vacas foram alocadas em dois quadrados latinos 4 x 4 compostos de quatro animais cada e quatro tratamentos em um esquema fatorial 2 x 2. Os suplementos foram formulados para um consumo de 0,6% do peso corporal: sem utilização de nitrogênio ureico; ou com 21% de nitrogênio ureico em sua composição. O manejo do pastejo de ponta melhorou o consumo e a digestibilidade dos nutrientes. O suplemento contendo ureia excretou 47% a mais de N urina (g/dia) em comparação ao suplemento sem ureia. A combinação entre o suplemento sem ureia e o manejo de pastejo ponta apresentou maior ingestão e retenção de nitrogênio e maior N retido (%N digerido). A combinação entre o suplemento contendo 21% de nitrogênio ureico e o pastejo de ponta pode ser utilizada sem prejuízos aos parâmetros nutricionais e produtivos das vacas.

Abstract This study aimed to evaluate the effect of the first and last stocking strategies combined with a partial substitution of the protein from the supplement for urea nitrogen on nutrient intake and digestibility, milk composition, and nitrogen balance of primiparous Girolando cows. The cows were allocated to a double 4 × 4 Latin square composed of four animals and four treatments in a 2 × 2 factorial arrangement. Supplements were formulated to provide an intake of 0.6% body weight, with and without the inclusion of 21% urea nitrogen in their composition. The first stocking management method improved nutrient intake and digestibility. Supplementation with urea led to a 47% higher excretion of urine N (g/day) than the urea treatment. The combination of the supplement without urea and the first stocking provided higher intake and retention of nitrogen and higher retained-N levels (%digested N). The combination of a supplement containing 21% urea nitrogen and the first stocking can be used without compromising the nutritional and productive parameters of the cows.

https://doi.org/10.1590/1809-6891v23e-72333e

COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.

; Rocco, Isadora

; Pimentel, Wallace S.

; Pinheiro, Aislan H. B.

; Souza, Paulo M. S.

; Costa, Luiz A. A.

; Teixeira, Marjory M. P.

; Ohashi, Leonardo P.

; Bublitz, Caroline

; Begot, Isis

; Moreira, Rita Simone L

; Hossne Jr, Nelson A.

; Vargas, Guilherme F.

; Branco, João Nelson R.

; Teles, Carlos A.

; Medeiros, Eduardo A. S.

; Sáfadi, Camila

; Rampinelli, Amândio

; Moratelli Neto, Leopoldo

; Rosado, Anderson Rosa

; Mesacasa, Franciele Kuhn

; Capriata, Ismael Escobar

; Segalote, Rodrigo Coelho

; Palmieri, Deborah Louize da Rocha Vianna

; Jardim, Amanda Cristina Mendes

; Vianna, Diego Sarty

; Coutinho, Joaquim Henrique de Souza Aguiar

; Jazbik, João Carlos

; Coutinho, Henrique Madureira da Rocha

; Kikuta, Gustavo

; Almeida, Zely Sant'Anna Marotti de

; Feguri, Gibran Roder

; Lima, Paulo Ruiz Lucio de

; Franco, Anna Carolina

; Borges, Danilo de Cerqueira

; Cruz, Felipe Ramos Honorato De La

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Goraieb, Lilian

; Postigo, Karolyne Barroca Sanches

; Jucá, Fabiano Gonçalves

; Oliveira, Fátima Rosane de Almeida

; Souza, Rafael Bezerra de

; Zilli, Alexandre Cabral

; Mas, Raul Gaston Sanchez

; Bettiati Junior, Luiz Carlos

; Tranchesi, Ricardo

; Bertini Jr, Ayrton

; Franco, Leandro Vieira

; Fernandes, Priscila

; Oliveira, Fabiana

; Moraes Jr, Roberto

; Araújo, Thiago Cavalcanti Vila Nova de

; Braga, Otávio Penna

; Pedrosa Sobrinho, Antônio Cavalcanti

; Teixeira, Roberta Tavares Barreto

; Camboim, Irla Lavor Lucena

; Gomes, Eduardo Nascimento

; Reis, Pedro Horigushi

; Garcia, Luara Piovan

; Scorsioni, Nelson Henrique Goes

; Lago, Roberto

; Guizilini, Solange

Brazilian Journal of Cardiovascular Surgery

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dec 2021, Volume 36 N. 6 Pages 725 - 735

Abstract: En | Text: En | PDF: En

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

https://doi.org/10.21470/1678-9741-2021-0960

Construction supply chain management: a scoping review
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Krainer, Jefferson Augusto

; Krainer, Christiane Wagner Mainardes

; Vidolin, Ana Celia

; Hasse, Frank Kiyoshi

; Romanel, Fabiano Barreto

; Romano, Cezar Augusto

Ambiente Construído

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oct 2021, Volume 21 N. 4 Pages 343 - 365

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Estudos relacionados à gestão da cadeia de suprimentos da construção (GCSC) despontaram em meados dos anos 90 para atender à natureza estrutural, econômica e organizacional típica da indústria da construção. Pesquisas anteriores buscaram revisar a literatura sobre GCSC, no entanto, geralmente concentradas em questões pontuais e bem definidas. Este artigo tem como objetivo mapear as atuais áreas e subáreas do GCSC. Adotando-se uma abordagem bibliométrica e seguindo-se as recomendações PRISMA-ScR uma revisão de escopo foi realizada. Com auxílio da ferramenta CiteSpace © as informações foram visualizadas em forma de rede de cocitações, proporcionando uma visão panorâmica de como as principais publicações estão distribuídas e interligadas em rede, formando áreas e subáreas de pesquisa. Os documentos chaves e os principais autores foram identificados; a situação atual e os pontos de interesse emergentes no campo do GCSC também foram revelados. Este artigo estabelece uma base de conhecimento para pesquisas futuras, podendo auxiliar estudiosos e gestores a identificarem autores, documentos e periódicos que precisam ser considerados ao lidarem com determinados tópicos do GCSC.

Abstract Studies related to construction supply chain management (CSCM) emerged in the mid-1990s to address the structural, economic and organizational nature typical of the construction industry. Previous researches sought to review the literature on CSCM, however, they usually focused on specific and well-defined issues. This article aimed to map the current areas and subareas of the CSCM. Adopting a bibliometric approach and following the PRISMA-ScR recommendations, a scoping review was carried out. With the help of the CiteSpace© tool, the information was viewed as a co-citation network, providing a panoramic view of how the main publications are distributed and networked, forming research areas and subareas. The key documents and the main authors were identified; the current situation and the emerging points of interest in the CSCM field were also revealed. This article establishes a knowledge base for future research, which can help scholars and managers to identify authors, documents and journals to be considered when dealing with certain topics of the CSCM.

https://doi.org/10.1590/s1678-86212021000400573

Bacteria and yeasts associated to Colonial cheese production chain and assessment of their hydrolytic potential
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Souza, Priscilla Vieira de

; Grecellé, Cristina B. Zaffari

; Barreto, Fabiano

; Ramírez-Castrillon, Maurício

; Valente, Patrícia

; Costa, Marisa da

Brazilian Journal of Food Technology

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2021, Volume 24 elocation e2020286

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Durante o processo de produção do queijo, é necessária a presença de diversos microrganismos que contribuem na sua elaboração pela ação de seu metabolismo. Pouco é conhecido sobre os microrganismos presentes no queijo Colonial, além daqueles inseridos para iniciar o processo ou daqueles indesejados, potenciais causadores de infecção ou intoxicação. Este trabalho teve como objetivo principal identificar, através de MALDI-TOF e/ou sequenciamento de DNA, bactérias e leveduras isoladas de amostras coletadas nas principais etapas de produção de queijo Colonial, um tipo de queijo produzido na Região Sul do Brasil. Também foi verificada a capacidade lítica destes microrganismos a 5 °C e 30 °C. Foram analisados 58 isolados de bactérias, sendo identificadas 10 espécies de bactérias distribuídas nos gêneros Bacillus, Lactococcus, Paenibacillus, Staphylococcus, Citrobacter, Klebsiella e Raoutella. Dos 13 isolados de leveduras, foram identificadas três espécies: Candida pararugosa, Meyerozyma guilliermondii e Rhodotorula mucilaginosa. Em três isolados de leveduras, foi possível a identificação somente dos gêneros Candida sp. e Trichosporon sp. As espécies Lactococcus lactis (48%) e M. guilliermondii (46%) foram os isolados predominantes de bactéria e levedura, respectivamente. A maior atividade lítica dos microrganismos identificados foi na temperatura de 30 °C. Proporcionalmente, foi verificado maior número de isolados com atividade de lipase pelas leveduras e maior atividade proteolítica pelas bactérias. Menor atividade de caseínase e lipase foi observada a 5 °C, demonstrando a importância da refrigeração no controle da atividade microbiana. Este trabalho mostrou, através de cultivo, alguns dos microrganismos que fazem parte da microbiota do queijo Colonial e que vários deles possuem capacidade de hidrolisar vários compostos presentes no leite. Mostrou também que podem estar associados com a maturação do mesmo ou, em circunstâncias não controladas, que poderiam ser a causa de deterioração do produto.

Abstract Different types of microorganisms are important in cheese-making because of the contributions their metabolism offers during the process. Few microorganisms present in Colonial cheese are known, in addition to the ones that are introduced to kick-start the processes or the ones that are associated with infections or poisonings. This study aimed to identify, by MALDI-TOF and/or DNA sequencing, the bacteria and yeasts isolated from samples collected in the main stages of Colonial cheese production, i.e., a type of cheese produced in the southern region of Brazil. The lytic capacity of these microorganisms at 5 °C and 30 °C was also evaluated. The 58 bacterial strains were distributed in 10 species among the genera Bacillus, Citrobacter, Klebsiella, Lactococcus, Paenibacillus, Staphylococcus and Raoutella. From the 13 yeasts strains analyzed, three species were identified as following: Candida pararugosa; Meyerozyma guilliermondii; and Rhodotorula mucilaginosa. In three yeasts isolates it was possible to identify only the genus Candida sp. and Trichosporon sp. The species L. lactis (48%) and M. guilliermondii (46%) were, respectively, the predominant bacteria and yeasts species isolated. The highest microbial lytic activity observed was at 30 °C. Lipase activity on isolates was proportionally more observed with yeasts and proteolytic activity with bacteria. Lower caseinase and lipase activity was observed at 5 °C, demonstrating the importance of refrigeration in controlling microbial activity. This research highlighted the cultivation of some microorganisms that are part of the Colonial cheese microbiota as well as that several of them can hydrolyze various compounds present in milk and that could be associated with its maturation or, in uncontrolled circumstances, could be the cause of product deterioration.

https://doi.org/10.1590/1981-6723.28620 93 downloads

Avermectins residues in milk produced in the state of Pernambuco
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MÜLLER, Patrícia Marinho

; MEDEIROS, Elizabeth Sampaio de

; MOTA, Rinaldo Aparecido

; ROLIM, Maria Betânia de Queiroz

; COLOMBO, Marcos Vinícius

; RÜBENSAM, Gabriel

; BARRETO, Fabiano

; SILVA, Daniel Dias da

; SILVA, Tamyres Izarelly Barbosa da

Food Science and Technology

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dec 2020, Volume 40 N. 4 Pages 979 - 984

Abstract: En | Text: En | PDF: En

Abstract Milk is a food widely consumed by the population, so it is important that it has adequate hygienic conditions and is free of chemical contaminants from various sources. This study aimed to evaluate the occurrence of avermectin residues in milk produced in the state of Pernambuco. The collections were performed in the dry and rainy season, being collected 60 and 48 samples, respectively, which were analyzed in the National Agricultural Laboratory of Rio Grande do Sul by liquid chromatography coupled with mass spectrometry. In the dry period, 46.7% (28/60) of samples with avermectin residues above the Limit of Detection (LD), 1.7% (01/60) with levels above the Quantifiable Limit (QL) and 51.6% (31/60) did not detect any residues. In the rainy season, 6.25% (03/48) presented residues above LD and in 93.75% (45/48) of samples there was no detection of residues. No samples were detected with amounts of avermectins above the Maximum Residue Limit in this study. The milk evaluated did not expose high risks to the health of the population, due to the low level of residues present. However, veterinary drug residue monitoring data are essential for assessing human exposure to these compounds.

https://doi.org/10.1590/fst.21919 346 downloads

Classification of chikungunya cases: a proposal
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Brito, Carlos Alexandre Antunes de

; Freitas, André Ricardo Ribas

; Said, Rodrigo Fabiano

; Falcão, Melissa Barreto

; Cunha, Rivaldo Venâncio da

; Siqueira, André Machado

; Teixeira, Maria Glória

; Ribeiro, Guilherme Sousa

; Brito, Marina Coelho Moraes de

; Cavalcanti, Luciano Pamplona de Góes

Revista da Sociedade Brasileira de Medicina Tropical

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2020, Volume 53 elocation e20200529

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0037-8682-0529-2020 504 downloads

10.

Chemical and mineralogical characterization of silicon manganese iron slag as railway ballast
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Oliveira, Ralph Werner Heringer

; Fernandes, Gilberto

; Sousa, Fabiano Carvalho

; Barreto, Rairane Aparecida

REM - International Engineering Journal

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dec 2017, Volume 70 N. 4 Pages 385 - 391

Abstract: En | Text: En | PDF: En

Abstract In nature, metal ores such as iron, lead, aluminum and others are found in an impure state, sometimes oxidized and mixed with silicates of other metals. During casting, when the ore is exposed to high temperatures, these impurities are separated from the molten metal and can be removed. The mass formed by these compounds is slag. Slag is the co-product of the smelting of ore to purify metals. It may be considered a mixture of metal oxides, but may also contain metal sulphites and metal atoms in their elemental form. After it is reprocessed to separate the metals contained, the co-products of this process can be used in cement, rail ballast, road paving and various other purposes. The objective of this research work is the presentation of the chemical and mineralogical characterization tests of the silicon-manganese iron slag with the purpose of reusing the co-product as rail ballast. X-ray diffraction tests, quantitative chemical analyzes, scanning electron microscopy and free lime content were prepared for these characterizations. The results of these tests showed the technical feasibility of using slag as rail ballast.

https://doi.org/10.1590/0370-44672017700019 3931 downloads

11.

ATENCIÓN BIOÉTICA DE LA VULNERABILIDAD DE LOS AUTISTAS: LA ODONTOLOGIA EN LA ESTRATEGIA DE SALUD DE LA FAMILIA
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David Amaral, Lais

; Fabiano de Carvalho, Talita

; Barreto Bezerra, Ana Cristina

Revista Latinoamericana de Bioética

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jan 2016, Volume 16 N. 1 Pages 220 - 233

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

El objetivo de este artículo es describir y discutir el enfoque y la intervención odontológica en autistas, así como la participación de la familia y de los profesionales de la salud oral en este contexto. Se cree que los principios de atención básica de la salud oral pueden ser aplicados en autistas y se sugiere un protocolo de atención odontológica al autista, dirigido a la práctica en los servicios de salud pública. Por tanto, son necesarios nuevos cuestionamientos enfocados a elevar la calidad de la atención odontológica al paciente autista, sobre todo en el Sistema Único de Salud y particularmente en la Estrategia de Salud de la Familia, en la atención de esta población vulnerable, con un enfoque bioético.

The aim of this article is to describe and discuss the dental approach and intervention in autistics, as the engagement of the family and oral health professionals in this subject. It is believed that the principles of basic attention may be applied in autistics and a protocol of autistics dental care is suggested, directed to practice in public health services. Thus the need of new questionings in order to increase the quality of the dentistry attention to the autistic patient, especially in the Unified Health System and particularly in the Family Health Strategy, in the attendance of this vulnerable population with a bioethics focus.

O objetivo deste artigo é descrever e discutir a abordagem e intervenção odontológicas em autistas, assim como a participação da família e dos profissionais de saúde bucal neste contexto. Acredita-se que os princípios de atenção básica podem ser aplicados em autistas e sugere-se um protocolo de atenção odontológica ao autista, orientado às práticas nos serviços públicos de saúde. Assim, sendo necessários novos questionamentos orientados a elevar a qualidade da atenção ao paciente autista pela odontologia, especialmente no Sistema Único de Saúde e particularmente na Estratégia Saúde da Família, no atendimento desta população vulnerável, em um enfoque bioético.

https://doi.org/10.18359/rlbi.1465 3856 downloads

12.

Synthesis and Photophysical Characterization of Novel ESIPT Triazinyl-Benzazole Derivatives
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Grasel, Fábio S.

; Barreto, Fabiano

; Jank, Louise

; Stefani, Valter

Journal of the Brazilian Chemical Society

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dec 2015, Volume 26 N. 12 Pages 2496 - 2506

Abstract: En | Text: En | PDF: En

In this work, the synthesis, characterization and photophysical study of new derivatives of triazinyl-benzazoles with fluorescence by excited-state intramolecular proton transfer (ESIPT) are presented. It regards the synthesis of cyanuric chloride with different 2-(2’-hydroxyphenyl) benzazoles, two quite attractive groups from the synthetic and technological point of view. These new compounds have several potential applications such as biological markers and new photoluminescent materials. The derivatives were characterized by 1H and 13C nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR), high-resolution mass spectrometry (HRMS), UV-Vis absorption and fluorescence emission. The dyes are fluorescent by an excited-state ESIPT in the blue-orange region, with a large Stokes’ shift.

https://doi.org/10.5935/0103-5053.20150148 1339 downloads

13.

Uso inadequado de organofosforados: uma prática de risco para bovinos no Sul do Rio Grande do Sul
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Santos, Bianca L.

; Marcolongo-Pereira, Clairton

; Stigger, Adriana L.

; Coelho, Ana Carolina B.

; Soares, Mauro P.

; Sallis, Eliza S.V.

; Barreto, Fabiano

; Schild, Ana Lucia

Pesquisa Veterinária Brasileira

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jul 2014, Volume 34 N. 7 Pages 655 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Com o objetivo de determinar as causas para o súbito aumento no número de surtos de intoxicação por organofosforados foram analisados nove surtos da intoxicação diagnosticados em bovinos no Laboratório Regional de Diagnóstico da Faculdade de Veterinária da Universidade Federal de Pelotas (LRD/UFPel) entre novembro de 2013 e fevereiro de 2014. Em todos os surtos os animais foram tratados com concentrações entre duas e 151 vezes maiores que a concentração recomendada de diazinon para banho carrapaticida utilizado nas diferentes propriedades. Contribuíram, ainda, para o grande número de casos de intoxicação a via de adminstração pour on não recomendada para os produtos utilizados e o intenso calor registrado na época de ocorrência dos surtos.

In order to determine the cause of the sudden increase in the number of outbreaks of organophosphate poisoning, nine outbreaks diagnosed in cattle were analyzed at the Laboratório Regional de Diagnóstico, Faculdade de Veterinária, Universidade Federal de Pelotas (LRD/UFPel) between November 2013 and February 2014. In all outbreaks the animals were treated with concentration from two to 151 times higher than the concentration recommended of diazinon for tick treatment. The incorrect route of application, and the intense heat recorded at the time of the outbreaks also contributed to the large number of poisoning.

5612 downloads

14.

Chemical constituents and pharmacological profile of Gunnera manicata L. extracts
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Mariotti, Kristiane de Cássia

; Schuh, Roselena Silvestri

; Nunes, Jéssica de Matos

; Salamoni, Sabrina Pinto

; Meirelles, Gabriela

; Barreto, Fabiano

; Poser, Gilsane Lino Von

; Singer, Rodrigo Bustos

; Dallegrave, Eliane

; Sand, Sueli Teresinha Van Der

; Limberger, Renata Pereira

Brazilian Journal of Pharmaceutical Sciences

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mar 2014, Volume 50 N. 1 Pages 147 - 154

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Gunnera perpensa L. (Gunneraceae) é uma planta nativa do sul da África utilizada na medicina tradicional como antibiótico e antifúngico. Gunnera manicata L. é uma planta nativa do sul do Brasil também da família Gunneraceae e, apesar disso, não há informações sobre suas propriedades químicas e farmacológicas. Assim, o objetivo deste estudo foi avaliar o perfil fitoquímico e farmacológico dos extratos aquoso e metanólico de G. manicata. Os resultados do ensaio microbiológico de difusão em ágar demonstraram que os extratos testados foram ativos contra Staphylococcus aureus e Candida albicans. A presença de compostos fenólicos foi investigada pela técnica de Cromatografia Líquida acoplada a espectrômetro de massas em Tandem (CL-EM/EM). Em todas as amostras analisadas verificou-se a presença de ácido gálico e somente o extrato metanólico das folhas apresentou hiperosídeo. Rutina, quercetina e ácido clorogênico não foram encontrados. O conteúdo total de compostos fenólicos foi maior nos extratos metanólicos e o conteúdo de flavonóides totais foi baixo em todos os extratos. A atividade antioxidante foi avaliada pelo teste da atividade do radical 2,2-diphenyl-1-picril-hidrazil (DPPH) e todas as amostras apresentaram boa a moderada atividade antioxidante. Esses resultados encorajam estudos complementares da composição química dos extratos com foco no isolamento e na elucidação estrutural dos compostos ativos.

Gunnera perpensa L. (Gunneraceae) is a native South African plant widely used in traditional medicine as an antibacterial and antifungal. In southern Brazil there is the native species called Gunnera manicata L. that also belongs to the Gunneraceae. Nevertheless, there is no information about chemical and pharmacological properties of South American Gunnera species. Therefore this study aimed at assessing the phytochemical and pharmacological profiles of aqueous and methanol Brazilian G. manicata extracts. The results showed that antimicrobial activity in an agar diffusion assay was effective against Staphylococcus aureus and Candida albicans . Phenolic compounds were investigated by liquid chromatography coupled with a tandem mass spectrometer (LC-MS/MS) and all extracts presented gallic acid and only the methanol extract obtained from the leaves exhibited hyperoside. Rutin, quercetin and chlorogenic acid were not found in the samples analysed. Total phenolic content was higher in methanol extract and total flavonoid content was low in all extracts. Antioxidant activity was evaluated by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical test, and all samples presented good to moderate antioxidant activity. These results encourage complementary studies on the chemical composition of the plant extracts focusing on isolation and structure elucidation of their active compounds.

https://doi.org/10.1590/S1984-82502014000100015 3880 downloads Cited 1 time in SciELO

15.

IV Consenso Brasileiro para pesquisa de autoanticorpos em células HEp-2
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Francescantonio, Paulo Luiz Carvalho

; Cruvinel, Wilson de Melo

; Dellavance, Alessandra

; Andrade, Luis Eduardo Coelho

; Taliberti, Ben Hur

; von Mühlen, Carlos Alberto

; Bichara, Carlos David Araújo

; Bueno, Cleonice

; Mangueira, Cristóvão Luis Pitangueira

; Carvalho, Darlene Gonçalves

; Bonfá, Eloísa S.D. de O.

; Brito, Fabiano de Almeida

; Araújo, Flávia Ikeda e

; Rêgo, Jozelia

; Pereira, Kaline Medeiros Costa

; Anjos, Lisiane Maria Enriconi dos

; Bissoli, Maria de Fatima

; Santiago, Mittermayer Barreto

; Maluf, Natalya Zaidan

; Alvarenga, Rossana Rassi

; Neves, Suzane Pretti Figueiredo

; Valim, Valeria

; Santos, Wilton Silva dos

Revista Brasileira de Reumatologia

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feb 2014, Volume 54 N. 1 Pages 44 - 50

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: O IV Consenso Brasileiro para Pesquisa de Autoanticorpos em Células HEp-2 (FAN) realizado em Vitória (ES), no dia 18 de setembro de 2012, objetivou discutir estratégias e recomendações relacionadas ao procedimento técnico, à padronização e à interpretação dos resultados da pesquisa de autoanticorpos em células HEp-2. Métodos: Participaram do evento 23 pesquisadores e especialistas de Universidades e laboratórios brasileiros. Foram abordados diferentes tópicos, discutidos amplamente a fim de se estabelecer recomendações específicas. Resultados e conclusão: O IV Consenso integrou à árvore de decisão o padrão citoplasmático em Anéis e Bastões, o padrão nuclear pontilhado Quasi-homogêneo (QH) e o padrão misto CENP-F. Discutiu-se ainda a necessidade de atenção para a classificação do padrão misto relacionado à presença de anticorpos anti-DNA topoisomerase I (Scl70), compreendendo os componentes nuclear pontilhado fino, nucleolar homogêneo, NOR na placa metafásica e citoplasmático pontilhado fino. Foram sugeridas diretrizes para o controle de qualidade do teste, diluição de triagem e diluição de esgotamento, e foi emitido alerta quanto à necessidade de atenção em relação à heterogeneidade de substratos disponíveis no mercado e a utilização de metodologias automatizadas para detecção de autoanticorpos.

Objective: The Fourth Brazilian Consensus for Autoantibodies Screening in HEp-2 Cells (ANA) was held in Vitória, Espírito Santo, and aimed to discuss strategies and recommendations about the technique, standardization, interpretation and quality control of the indirect immunofluorescence reaction on HEp-2 cells. Methods: Twenty three ANA experts from university centers and private laboratories in different areas from Brazil discussed and agreed upon recommendations for the fourth edition of the Brazilian Consensus for Autoantibodies Screening in HEp-2 Cells. Results and conclusion: The 4th ANA Consensus included three novel patterns into the existing algorithm (cytoplasmic Rods and Rings, nuclear Quasi-homogeneous, and CENP-F). Emphasis was given to the need of attention in describing the peculiar mixed pattern elicited by anti-DNA topoisomerase I (Scl-70) autoantibodies, comprising nuclear fine specked, nucleolar homogeneous pattern, NOR staining in metaphase plates, and cytoplasmic fine speckled patterns. The group also emphasized the need for continuous quality control in indirect immunofluorescence assays, the establishment of screening dilutions, as well as conjugate titration. An alert was made regarding the heterogeneity of commercial kits in defining patterns and the use of solid phase methodologies to determine the presence of autoantibodies.

https://doi.org/10.1016/j.rbr.2013.10.001 28365 downloads

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