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Stress level and quality of life following pediatric cataract surgery
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Koch, Camila Ribeiro

; Parahyba, Marcelle Oliveira

; Barros, Adriana Nascimento Alves de

; Leite, Marcela Macedo

; Souza, Ângela Cristina Santana

; Bastos, Joana Anjos

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 3 elocation e2021-0493

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: To evaluate the quality of life and stress level related to visual function following pediatric cataract surgery in a Brazilian public hospital. Methods: This prospective study analyzed children aged 6-14 years old who underwent cataract surgery. The Childhood Stress Scale and Children’s Visual Function Questionnaire (CVFQ) were used to assess stress levels and quality of life, respectively. Both instruments were applied by two psychologists before and after the surgery. Eye examination was performed by two ophthalmologists. Preoperative and postoperative data were compared. Results: In total, 23 children (32 eyes) were enrolled in the study, of which 9 had bilateral cataracts. The average age group at the time of surgery was 9.65 ± 2.26 (6-14) years old. One month after the surgery, the spherical equivalent was -0.90 ± 1.66D, and the corrected distance visual acuity was 0.13 ± 0.10 (0-0.3) LogMAR in bilateral cases and 0.50 ± 0.39 (0-1.3) LogMAR in unilateral cases (p<0.01). According to the Childhood Stress Scale, 77.7% of the bilateral cases and 57.1% of the unilateral cases had stable stress levels, and 34.7% of the children improved their stress level. The analysis of the CVFQ was based on scores for general health, general vision health, competence, personality, and treatment. After cataract surgery, 78.2% of the patients had improved or maintained CVFQ scores in the general health domain; 82.6%, general vision health; 95.6%, competence; 56.5%, personality; and 78.2%, treatment. Conclusion: Pediatric cataract surgery improves the visual function and the quality of life even in patients undergoing surgical procedures, without increasing the stress levels.

RESUMO Objetivo: Avaliar a qualidade de vida e o nível de estresse relacionada à função visual após a cirurgia de catarata pediátrica em um hospital público brasileiro. Métodos: Estudo prospectivo em crianças de seis a 14 anos submetidas à cirurgia de catarata. A Escala de Stresse Infantil e o Questionário de Função Visual em Crianças foram usados para avaliar o nível de estresse e a qualidade de vida, respectivamente. Ambos os instrumentos foram aplicados por duas psicólogas antes e após a cirurgia. O exame oftalmológico foi realizado por dois oftalmologistas. Os dados coletados no pré e pós-operatório foram comparados. Resultados: Vinte e três crianças (32 olhos) foram incluídas no estudo, nove delas apresentavam catarata bilateral. A média de idade na cirurgia foi de 9,65±2,26 (6 a 14) anos. Um mês após a cirurgia, o equivalente esférico foi de -0,90 ± 1,66D e a acuidade visual corrigida a distância foi de 0,13 ± 0,10 (0-0,3) LogMAR em casos bilaterais e 0,50 ± 0,39 (0-1,3) LogMAR em casos unilaterais (p<0.01). De acordo com a Escala de Stresse Infantil, 77,7% dos casos de catarata bilaterais, e 57,1% dos casos unilaterais mantiveram o nível de estresse e 34,7% das crianças melhoraram o nível de estresse. A análise do Questionário de Função Visual em Crianças foi baseada em pontuações para saúde geral, saúde geral da visão, competência, personalidade e tratamento. Após a cirurgia de catarata, 78,2% dos pacientes melhoraram ou mantiveram o escore do Questionário de Função Visual em Crianças na saúde geral, 82,6% na saúde geral da visão, 95,6% na competência, 56,5% na personalidade e 78,2% no tratamento. Conclusão: A cirurgia de catarata pediátrica melhora a função visual e a qualidade de vida em pacientes submetidos a procedimento cirúrgico, sem aumentar o nível de estresse.

https://doi.org/10.5935/0004-2749.2021-0493

Retromolar canal diagnosed by cone-beam computed tomography and its influence in inferior alveolar nerve block
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Costa, Eliana Dantas

; Fortes, João Henrique Parise

; Cruvinel, Pedro Bastos

; Gaêta-Araujo, Hugo

; Mendonça, Lucas Moreira

; Freitas, Bruna Neves de

; Pedrazzi, Vinícius

; Oliveira-Santos, Christiano

; Tirapelli, Camila

Odovtos International Journal of Dental Sciences

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apr 2023, Volume 25 N. 1 Pages 135 - 141

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen El objetivo de este estudio fue observar la eficacia anestésica del bloqueo del nervio alveolar en nueve pacientes que CBCT diagnosticó canal retromolar unilateral en un abordaje de boca dividida doble ciego. Las evaluaciones de la respuesta del paciente a los estímulos térmicos (prueba de vitalidad pulpar) y de presión (compresión de los tejidos blandos) se realizaron antes y 5 minutos después del procedimiento de bloqueo del nervio alveolar inferior, utilizando tanto la escala analógica visual (VAS) como los cuestionarios de dolor de Mc Gill ( McG). El porcentaje medio de respuesta de los pacientes disminuyó tras el bloqueo del nervio alveolar, según EVA y McG, y fue estadísticamente similar entre hemimandíbulas con y sin canal retromolar (Wilcoxon>0,05); sin embargo, aquellos sin canal retromolar presentaron mayor reducción en la respuesta del paciente en 6 de 9 casos. Por lo tanto, el canal retromolar no es un factor determinante del fracaso del bloqueo del nervio alveolar inferior.

Abstract The aim of this study was to observed the anesthetic efficacy of the alveolar nerve block on nine patients that CBCT diagnosed unilateral retromolar canal on a double-blind, split-mouth approach. The assessments of patient response to thermal (pulp vitality test) and pressure (compression of soft tissue) stimuli were carried out before and 5 minutes after the inferior alveolar nerve block procedure, using both visual analog scale (VAS) and Mc Gill pain questionnaires (McG). The mean percentage of patient response decreased after alveolar nerve block, according to both VAS and McG, and was statistically similar among hemi mandibles with and without retromolar canal (Wilcoxon>0.05); however, those without retromolar canal presented greater reduction in patient response in 6 out of 9 cases. Therefore, the retromolar canal is not a determinant factor of inferior alveolar nerve block failure.

https://doi.org/10.15517/ijds.2022.52179

Stress level and quality of life following pediatric cataract surgery
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Koch, Camila Ribeiro

; Parahyba, Marcelle Oliveira

; Barros, Adriana Nascimento Alves de

; Leite, Marcela Macedo

; Souza, Ângela Cristina Santana

; Bastos, Joana Anjos

Arquivos Brasileiros de Oftalmologia

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2023, N. ahead

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/0004-2749.2021-0493

INTRAPERITONEAL CHEMOTHERAPY FOR GASTRIC CANCER WITH PERITONEAL CARCINOMATOSIS: STUDY PROTOCOL OF A PHASE II TRIAL
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Ramos, Marcus Fernando Kodama Pertille

; Pereira, Marina Alessandra

; Charruf, Amir Zeide

; Victor, Carolina Ribeiro

; Gregorio, João Vitor Antunes Marques

; Alban, Luciana Bastos Valente

; Moniz, Camila Motta Venchiarutti

; Zilberstein, Bruno

; Mello, Evandro Sobroza de

; Hoff, Paulo Marcelo Gehm

; Ribeiro Junior, Ulysses

; Dias, Andre Roncon

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2023, Volume 36 elocation e1744

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND: Peritoneal carcinomatosis in gastric cancer is considered a fatal disease, without expectation of definitive cure. As systemic chemotherapy is not sufficient to contain the disease, a multimodal approach associating intraperitoneal chemotherapy with surgery may represent an alternative for these cases. AIMS: The aim of this study was to investigate the role of intraperitoneal chemotherapy in stage IV gastric cancer patients with peritoneal metastasis. METHODS: This study is a single institutional single-arm prospective clinical trial phase II (NCT05541146). Patients with the following inclusion criteria undergo implantation of a peritoneal catheter for intraperitoneal chemotherapy: Stage IV gastric adenocarcinoma; age 18–75 years; Peritoneal carcinomatosis with peritoneal cancer index<12; Eastern Cooperative Oncology Group 0/1; good clinical status; and lab exams within normal limits. The study protocol consists of four cycles of intraperitoneal chemotherapy with paclitaxel associated with systemic chemotherapy. After treatment, patients with peritoneal response assessed by staging laparoscopy undergo conversion gastrectomy. RESULTS: The primary outcome is the rate of complete peritoneal response. Progression-free and overall survivals are other outcomes evaluated. The study started in July 2022, and patients will be screened for inclusion until 30 are enrolled. CONCLUSIONS: Therapies for advanced gastric cancer patients have been evaluated in clinical trials but without success in patients with peritoneal metastasis. The treatment proposed in this trial can be promising, with easy catheter implantation and ambulatory intraperitoneal chemotherapy regime. Verifying the efficacy and safety of paclitaxel with systemic chemotherapy is an important progress that this study intends to investigate.

RESUMO RACIONAL: A carcinomatose peritoneal no câncer gástrico é considerada uma doença fatal, sem expectativa de cura definitiva. Como a quimioterapia sistêmica não é suficiente para conter a doença, uma abordagem multimodal associando a quimioterapia intraperitoneal à cirurgia pode representar uma alternativa para esses casos. OBJETIVOS: Investigar o papel da quimioterapia intraperitoneal em pacientes com câncer gástrico estágio IV com metástases peritoneais. MÉTODOS: Trata-se de um ensaio clínico prospectivo unicêntrico, braço único, fase II (NCT05541146). Pacientes com os seguintes critérios de inclusão serão submetidos à implantação de cateter peritoneal para quimioterapia intraperitoneal: adenocarcinoma gástrico estágio IV; idade 18-75 anos; carcinomatose peritoneal com índice de câncer peritoneal<12; ECOG 0/1; bom estado clínico e exames laboratoriais dentro da normalidade. O protocolo do estudo consiste em 4 ciclos de quimioterapia intraperitoneal com Paclitaxel associado à quimioterapia sistêmica. Após o tratamento, os pacientes com resposta peritoneal avaliada por laparoscopia serão submetidos à gastrectomia de conversão. RESULTADOS: O desfecho primário é a taxa de resposta peritoneal completa. A sobrevida livre de progressão e global são outros desfechos avaliados. O estudo foi iniciado em julho de 2022 e os pacientes serão selecionados para inclusão até que 30 sejam inscritos. CONCLUSIONS: Terapias para pacientes com câncer gástrico avançado foram avaliadas em ensaios clínicos, mas sem sucesso em pacientes com metástase peritoneal. O tratamento proposto neste estudo pode ser promissor, com fácil implantação do cateter e regime de quimioterapia intraperitoneal ambulatorial. Verificar a eficácia e segurança do Paclitaxel associado à quimioterapia sistêmica é um progresso importante que o presente estudo pretende investigar.

https://doi.org/10.1590/0102-672020230026e1744

Comparative evaluation of three laparoscopic cholecystectomy techniques in rabbit’s model
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Wittmaack, Monica Carolina Nery

; Conceição, Maria Eduarda Bastos Andrade Moutinho

; Vera, María Camila Maldonado

; Faccini, Rachel Inamassu

; Sembenelli, Guilherme

; Montanhim, Gabriel Luiz

; Menezes, Mareliza Possa de

; Rocha, Fabiana Del Lama

; Aires, Luiz Paulo Nogueira

; Moraes, Paola Castro

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e383523

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: The aim of this randomized study was to compare the complications and perioperative outcome of three different techniques of laparoscopic cholecystectomy (LC). Changes in the liver function test after LC techniques were investigated. Also, we compared the degree of postoperative adhesions and histopathological changes of the liver bed. Methods: Thirty rabbits were divided into three groups: group A) Fundus-first technique by Hook dissecting instrument and Roeder Slipknot applied for cystic duct (CD) ligation; group B) conventional technique by Maryland dissecting forceps and electrothermal bipolar vessel sealing (EBVS) for CD seal; group C) conventional technique by EBVS for gallbladder (GB) dissection and CD seal. Results: Group A presented a longer GB dissection time than groups B and C. GB perforation and bleeding from tissues adjacent to GB were similar among tested groups. Gamma-glutamyl transferase and alkaline phosphatase levels increased (p ≤ 0.05) on day 3 postoperatively in group A. By the 15th postoperative day, the enzymes returned to the preoperative values. Transient elevation of hepatic transaminases occurred after LC in all groups. Group A had a higher adherence score than groups B and C and was associated with the least predictable technique. Conclusions: LC can be performed using different techniques, although the use of EBVS is highly recommended.

https://doi.org/10.1590/acb383523

Brazilian practice guidelines for stroke rehabilitation: part II
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Minelli, Cesar

; Luvizutto, Gustavo José

; Cacho, Roberta de Oliveira

; Neves, Luciana de Oliveira

; Magalhães, Sheila Cristina Sayuri Abe

; Pedatella, Marco Túlio Araújo

; Mendonça, Lucia Iracema Zanotto de

; Ortiz, Karin Zazo

; Lange, Marcos Christiano

; Ribeiro, Priscila Watson

; Souza, Luciane Aparecida Pascucci Sande de

; Milani, Cristiano

; Cruz, Daniel Marinho Cezar da

; Costa, Rafael Dalle Molle da

; Conforto, Adriana Bastos

; Carvalho, Fernanda Martins Maia

; Ciarlini, Bruna Silva

; Frota, Norberto Anizio Ferreira

; Almeida, Kelson James

; Schochat, Eliane

; Oliveira, Tatiana de Paula

; Miranda, Camila

; Piemonte, Maria Elisa Pimentel

; Lopes, Laura Cardia Gomes

; Lopes, Camila Galvão

; Tosin, Michelle Hyczy de Siqueira

; Oliveira, Bianca Campos

; Oliveira, Beatriz Guitton Renaud Baptista de

; Castro, Shamyr Sulyvan de

; Andrade, João Brainier Clares de

; Silva, Gisele Sampaio

; Pontes-Neto, Octávio Marques

; Carvalho, João José Freitas de

; Martins, Sheila C. Ouriques

; Bazan, Rodrigo

Arquivos de Neuro-Psiquiatria

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jul 2022, Volume 80 N. 7 Pages 741 - 758

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The Brazilian Practice Guidelines for Stroke Rehabilitation – Part II, developed by the Scientific Department of Neurological Rehabilitation of the Brazilian Academy of Neurology (Academia Brasileira de Neurologia, in Portuguese), focuses on specific rehabilitation techniques to aid recovery from impairment and disability after stroke. As in Part I, Part II is also based on recently available evidence from randomized controlled trials, systematic reviews, meta-analyses, and other guidelines. Part II covers disorders of communication, dysphagia, postural control and balance, ataxias, spasticity, upper limb rehabilitation, gait, cognition, unilateral spatial neglect, sensory impairments, home rehabilitation, medication adherence, palliative care, cerebrovascular events related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the future of stroke rehabilitation, and stroke websites to support patients and caregivers. Our goal is to provide health professionals with more recent knowledge and recommendations for better rehabilitation care after stroke.

Resumo As Diretrizes Brasileiras de Reabilitação do Acidente Vascular Cerebral (AVC) - Parte II, desenvolvida pelo Departamento Científico de Reabilitação Neurológica da Academia Brasileira de Neurologia é voltada para intervenções específicas de técnicas de reabilitação de déficits neurológicos e incapacidades. Seguindo o mesmo modelo da Parte I, a Parte II também se baseia em estudos randomizados, revisões sistemáticas, metanálises e outras diretrizes sobre o mesmo tema. A segunda parte aborda os distúrbios da comunicação, disfagia, controle postural e equilíbrio, ataxias, espasticidade, reabilitação do membro superior, marcha, cognição, negligência espacial unilateral, déficits sensoriais, reabilitação domiciliar, aderênciaao usode medicamentos, cuidados paliativos,ofuturodareabilitação no AVC, e websites de orientação sobre AVC para pacientes e cuidadores. Nosso objetivo é fornecer aos profissionais envolvidos na reabilitação conhecimento atualizado e recomendações para um melhor cuidado no pós-AVC.

https://doi.org/10.1055/s-0042-1757692

Development and optimization of the jam production process of Pouteria cf. gardneriana Radlk (guapeva)
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SOARES, Camila Mariane da Silva

; MORAIS, Rômulo Alves

; SILVA, Romilda Ramos da

; FREITAS, Bárbara Catarina Bastos de

; MELO FILHO, Antonio Alves de

; MARTINS, Glêndara Aparecida de Souza

Food Science and Technology

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2022, Volume 42 elocation e00821

Abstract: En | Text: En | PDF: En

Abstract This work aimed to study the effect of citric acid and passion fruit albedo concentrations and pulp/sugar ratio in optimizing of jam production process of Pouteria cf. gardneriana Radlk (guapeva fruit) and evaluating the nutritional characteristics and functional properties of the developed jams. A factorial design 23 with 11 assays was used, considering citric acid concentration, pulp/sugar ratio, and albedo concentration as independent variables. Formulations containing a 50/50 pulp/sugar ratio proved to be excellent for quality parameters, the potential of phenolic compounds, antioxidants, and sensory properties. The formulation indicated as most desirable was the one containing a 40/60 sugar/pulp ratio. Guapeva proved to be a good alternative for jam production because even after thermal processing, it was possible to obtain jams rich in Vitamin C, phenolic compounds, and antioxidant potential.

https://doi.org/10.1590/fst.00821

Impact of COVID-19 on liver transplant recipients during the first pandemic wave, in a tertiary hospital, in Northeastern Brazil
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Neves, Marina Seixas Studart e

; Paiva, José Hícaro Hellano Gonçalves Lima

; Ferreira, Natália Stefani de Assunção

; Queiroz, Francisca Patrícia Almeida

; Limeira, Camilla Bezerra Bastos

; Veras, Camila Monteiro

; Carvalho, Themístocles Mesquita Teles de

; Freitas, Taina Veras de Sandes

; Esmeraldo, Ronaldo de Matos

; Brasil, Ivelise Regina Canito

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volume 64 elocation e8

Abstract: En | Text: En | PDF: En

ABSTRACT Worldwide, transplant programs have suffered a setback during the coronavirus disease 2019 (COVID-19) pandemic and most have temporarily suspended their transplant activities. . We identified 36 liver transplant patients who tested positive for COVID-19. The cases were confirmed by the nucleic acid test (RT-PCR). Epidemiological, demographic, clinical, laboratory, management and outcome data were obtained from the patients’ medical records. Fourteen patients (38.9%) required admission to the Intensive Care Unit and/or invasive ventilatory support (severe cases). The mean age of these severe cases was 63.8 years. Regarding the time since the transplant, 71.4% (10/14 patients) had undergone the procedure less than one year before. The immunosuppressive therapy was reduced in patients who required Intensive Care Unit. A total of 12 cases (12/14, 85.7%) required invasive ventilatory support. Eight cases (8/14, 57.1%) required renal replacement therapy. In this group of patients, nine died (64.3 %). In turn, 22 patients had mild to moderate symptoms of COVID-19, not requiring invasive ventilatory support or admission to the Intensive Care Unit. The mean age in these patients was 56.5 years and comorbidities were present in 15 (68.2%) of the cases. In this group, only five patients (5/22, 22.7%) required hospitalization due to complications and there were no deaths This report describes the results of COVID-19 infection in a very specific population, suggesting that liver transplant patients have a significant higher risk of progressing to severeCOVID-19 , with a mortality rate among critically-ill patients above that of the general population.

https://doi.org/10.1590/s1678-9946202264008

Household outbreak of sporotrichosis: towards the One Health approach
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Andrade, Elisa Helena Paz

; Bastos, Camila Valgas

; Silva, Afonso Vieira da

; Moreira, Simone Magela

; Costa, Taiza Gonçalves de Araújo

; Salvato, Lauranne Alves

; Colombo, Salene Angelini

; Oliveira, Camila Stefanie Fonseca de

; Soares, Danielle Ferreira de Magalhães

; Keller, Kelly Moura

; Azevedo, Maria Isabel de

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 elocation e0021-2022

Abstract: En | Text: En | PDF: En

ABSTRACT Although sporotrichosis requires a broad approach for control, few reports have described the relationship between the index case and secondary contacts. In the present work, we report an outbreak involving a woman, a dog, and two cats from the same household environment, including the clinical and epidemiological aspects and outcomes, and discuss the importance of a One Health approach to face this neglected disease. The joint efforts of professionals such as veterinarians and physicians are essential for early diagnosis and surveillance, which contributes to the rapid identification and control of zoonotic sporotrichosis outbreaks.

https://doi.org/10.1590/0037-8682-0021-2022

10.

Mupirocin ointments: In vitro x In vivo bioequivalence evaluation
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Chagas, Stephanye Carolyne Christino

; Pimenta, Camila de Almeida Perez

; Kishishita, Juliana

; Barbosa, Irla Carla França

; Bedor, Danilo Cesar Galindo

; Aquino, Katia Aparecida da Silva

; Santana, Davi Pereira de

; Leal, Leila Bastos

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e19426

Abstract: En | Text: En | PDF: En

Abstract Bioequivalence (BE) assessment of topical drug products is a long-standing challenge. Agencies such as the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have published several drafts in recent years suggesting different approaches as alternative to evaluate the BE. A proposed Topical Classification System (TCS) has even been discussed. Given the above, the objective of this research was to use in vitro and in vivo BE approaches to evaluate Brazilian marketed mupirocin (MPC) ointments, previously classified as TCS class The in vitro permeation test (IVPT) was performed by applying formulations to pig skin by Franz cells. The in vivo methodology was dermatopharmacokinetic (DPK). These approaches (in vivo tape stripping and IVPT) demonstrated capability of distinguishing among different formulations, thus making them useful methodologies for BE evaluation.

https://doi.org/10.1590/s2175-97902022e19426

11.

The health facility as a risk factor for multidrug-resistant gram-negative bacteria in critically ill patients with COVID-19
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de Macedo, Viviane

; dos Santos, Gabriela de Souza

; da Silva, Rodolff Nunes

; Couto, Caio Nogara de Menezes

; Bastos, Camila

; Viecelli, Eloize

; Mateus, Marina do Nascimento

; Graf, Maria Esther

; Gonçalves, Raquel Bernardelli

; da Silva, Márcia Aparecida

; Bernardini, Patricia Dal Bem

; Grando, Roberta Serra Pereira

; Boaventura, Viviane Pavanelo

; Pereira, Helki Simone Rodrigues

; Levin, Anna S.

Clinics

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2022, Volume 77 elocation 100130

Abstract: En | Text: En | PDF: En

Abstract Background The relationship between Multidrug Resistant-Gram Negative Bacteria (MDR-GNB) infection and colonization in critically ill COVID-19 patients has been observed, however, it is still poorly understood. This study evaluated the risk factors for acquiring MDR-GNB in patients with severe COVID-19 in Intensive Care Units (ICU). Methods This is a nested case-control study in a cohort of 400 adult patients (≥ 18 years old) with COVID-19, hospitalized in the ICU of 4 hospitals in the city of Curitiba, Brazil. Cases were critical COVID-19 patients with one or more MDR GNB from any surveillance and/or clinical cultures were taken during their ICU stay. Controls were patients from the same units with negative cultures for MDR-GNB. Bivariate and multivariate analyses were done. Results Sixty-seven cases and 143 controls were included. Independent risk factors for MDR bacteria were: male gender (OR = 2.6; 95% CI 1.28‒5.33; p = 0.008); the hospital of admission (OR = 3.24; 95% CI 1.39‒7.57; p = 0.006); mechanical ventilation (OR = 25.7; 95% CI 7.26‒91; p < 0.0001); and desaturation on admission (OR = 2.6; 95% CI 1.27‒5.74; p = 0.009). Conclusions Male gender, desaturation, mechanical ventilation, and the hospital of admission were the independent factors associated with MDR-GNB in patients in the ICU with COVID-19. The only modifiable factor was the hospital of admission, where a newly opened hospital posed a higher risk. Therefore, coordinated actions toward a better quality of care for critically ill COVID-19 patients are essential.

https://doi.org/10.1016/j.clinsp.2022.100130

12.

Growth performance, reproductive parameters and fertility measures in young Nellore bulls with divergent feed efficiency
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Rossi, Guilherme Fazan

; Bastos, Natália Marins

; Vrisman, Dayane Priscila

; Rodrigues, Naiara Nantes

; Vantini, Roberta

; Garcia, Joaquim Mansano

; Dias, Erika Aline Ribeiro

; Simili, Flávia Fernanda

; Guimarães, André Lasmar

; Canesin, Roberta Carrilho

; Mercadante, Maria Eugênia Zerlotti

; Freitas-Dell’Aqua, Camila de Paula

; Athayde, Flávia Regina Florencio de

; Monteiro, Fabio Morato

; Mingoti, Gisele Zoccal

Animal Reproduction

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2022, Volume 19 N. 3 elocation e20220053

Abstract: En | Text: En | PDF: En

Abstract The growth, sexual maturity and fertility-related parameters related of young Nellore bulls with divergent residual feed intake (RFI) raised on pasture were evaluated. After classification of 48 young males as low and high RFI (more and less efficient, respectively), the animals were evaluated for growth and reproductive parameters at 28-day intervals from 14.3 to 24.6 months of age. The semen was cryopreserved in the last sampling and fresh and post-thaw semen samples were evaluated. Low RFI bulls exhibited higher initial and final body weight (P < 0.05), but feed intake, body condition score and growth measures evaluated by carcass ultrasound were unaffected by RFI (P > 0.05). The scrotal circumference, sperm concentration, defects, and quality of fresh semen, and ultrasonographic testicular characteristics were unaffected by RFI (P > 0.05). However, velocity parameters such as average path and curvilinear velocities determined by computer-assisted sperm analysis of thawed semen submitted to the rapid thermoresistance test were improved (P < 0.05) in low RFI bulls, but this improvement in quality did not enhance in vitro sperm fertilizing ability. Our results demonstrated significant differences in metabolism and growth performance between bulls of divergent RFI. In addition, there was slight improvement in the semen quality of bulls with low RFI bulls, but this did not enhance in vitro fertilizing ability. Selection of beef bulls for RFI can be performed, which will result in economic benefits by improving the growth performance of the animals without affecting reproductive parameters.

https://doi.org/10.1590/1984-3143-ar2022-0053

13.

Formulation and evaluation of guapeva jam: nutritional properties, bioactive compounds, and volatile compounds during storage
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MORAIS, Rômulo Alves

; SOARES, Camila Mariane da Silva

; SILVA, Romilda Ramos da

; GUALBERTO, Larissa da Silva

; FREITAS, Bárbara Catarina Bastos de

; CARVALHO, Elisângela Elena Nunes

; MARTINS, Glêndara Aparecida de Souza

Food Science and Technology

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2022, Volume 42 elocation e116321

Abstract: En | Text: En | PDF: En

Abstract The guapeva (Pouteria cf. gardneriana Radlk.) is a Brazilian fruit that belongs to the Sapotaceae family and is considered a source of natural antioxidants and phenolic compounds; Thus, the objective of this work was to investigate the use of guapeva in the form of jam stored at different temperatures (25 °C and 35 °C) and to evaluate the degradation kinetics regarding the physicochemical parameters, bioactive compounds, and volatile profile, during the storage period of 150 days, in low-density polypropylene packaging’s. The stored jams were mainly influenced by the storage time variable, with significant reductions in titratable acidity, pH, color, vitamin C, carotenoids, ABTS●+, DPPH, and volatile profile. The temperatures studied were not able to significantly affect the shelf life determined for the jams; however, the best temperature for storage stability of the guapeva jams was 25 °C since the most significant degradation of the compounds occurs with the use of 35 °C. The correlation between time and temperature had no significant effect on carotenoid content.

https://doi.org/10.1590/fst.116321

14.

The effects of neuromuscular electrical stimulation on strength, pain, and function in individuals with knee osteoarthritis: a systematic review with meta-analysis
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Bispo, Vinícius Araújo

; Bastos, Júlia Aguillar Ivo

; Almeida, Camila Cadena de

; Modesto, Karenina Arrais Guida

; Dantas, Lucas Ogura

; Cipriano Júnior, Gerson

; Durigan, João Luiz Quagliotti

Fisioterapia e Pesquisa

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oct 2021, Volume 28 N. 4 Pages 416 - 426

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO O objetivo deste estudo foi investigar os efeitos da estimulação elétrica neuromuscular (EENM) na força muscular, alívio da dor e melhora da função em pacientes com osteoartrite de joelho. Realizou-se uma pesquisa em diferentes bases de dados, como PubMed, Embase, LILACS e o Cochrane Central Register of Controlled Trials, no período de dezembro de 2017 até julho de 2020. Procedeu-se a uma busca manual com o intuito de verificar as listas de referências dos artigos elegíveis. As diretrizes PRISMA foram seguidas. Os estudos selecionados comparavam a estimulação elétrica neuromuscular com um programa de exercícios de força muscular isométrica como desfecho primário. Os resultados secundários foram dor e função. A qualidade dos estudos foi avaliada usando avaliação de risco de viés e a escala PEDro e a qualidade geral das evidências foi avaliada usando a abordagem GRADE. Oito estudos foram incluídos nesta revisão sistemática com um total de 571 pacientes analisados. A EENM associada ao exercício promoveu o aumento da força isométrica do músculo quadríceps em relação ao grupo controle ativo, demonstrando heterogeneidade e diferença estatística (IC 95%=1,16 a 5,10, I2=97%, p=0,002; evidência de muito baixa certeza), mas não melhorou a função física (IC 95%=−0,37 a 0,59, I2=0%, p=0,67; evidência de baixa certeza) e mostrou resultados controversos para dor em comparação ao grupo de controle ativo (avaliação qualitativa). Conclui-se que a EENM induz o aumento da força muscular em pacientes com osteoartrite, porém não foram encontradas diferenças nos resultados de funcionalidade e dor em comparação com o grupo de controle ativo. Devido à incerteza das evidências, são necessárias mais pesquisas sobre o assunto.

ABSTRACT We aimed to investigate the effects of neuromuscular electrical stimulation on muscle strength, pain relief, and improvement in function in patients with knee osteoarthritis. Databases were searched from December 2017 to July 2020 and included PubMed, Embase, LILACS, and the Cochrane Central Register of Controlled Trials. A manual search was also performed by checking the reference lists of eligible articles. The PRISMA guidelines were followed. The studies selected compared NMES with an exercise program on isometric muscle strength as a primary outcome. The secondary outcomes were pain and function. The quality of the studies was assessed using the Risk of Bias assessment and PEDro scale, and the overall quality of the evidence was assessed using the GRADE approach. Eight studies were included in this systematic review. A total of 571 patients were analyzed. Neuromuscular electrical stimulation associated with exercise promoted an increase in isometric strength of the quadriceps muscle compared to the active control group, demonstrating heterogeneity and statistical difference (95% CI=1.16 to 5.10, I2=97%, p=0.002; very low-certainty evidence). NMES associated with exercise did not improve physical function (95% CI=−0.37 to 0.59, I2=0%, p=0.67; low-certainty evidence) and showed controversial results for pain compared to an active control group (qualitative assessment). In conclusion, NMES induces an increase in muscle strength in patients with osteoarthritis compared to an active control group. No differences were found for physical function and pain outcomes. Further research is needed due to the uncertain level of evidence.

RESUMEN El objetivo de este estudio fue analizar los efectos de la electroestimulación neuromuscular (NMES) sobre la fuerza muscular, el alivio del dolor y la mejora de la función en pacientes con osteoartritis de la rodilla. Se realizó una búsqueda en las bases de datos PubMed, Embase, LILACS y Cochrane Central Register of Controlled Trials, en el periodo de diciembre de 2017 y julio de 2020. Se llevó a cabo una búsqueda manual para verificar las listas de referencias de los artículos elegibles. Se aplicó las pautas PRISMA. Los estudios seleccionados compararon la electroestimulación neuromuscular con un programa de ejercicio de fuerza muscular isométrica como resultado primario. Los resultados secundarios fueron el dolor y la función. La calidad de los estudios se evaluó mediante la evaluación del riesgo de sesgo y la escala PEDro, y la calidad general de la evidencia se estimó con el uso del sistema GRADE. Ocho estudios con un total de 571 pacientes compusieron esta revisión sistemática. La EENM asociada con el ejercicio aumentó la fuerza isométrica del músculo cuádriceps en comparación con el grupo control activo, demostrando una heterogeneidad y diferencia estadística (IC 95%=1,16 a 5,10, I2=97%, p=0,002; evidencia con muy baja seguridad), pero no mejoró la función física (IC 95%=−0,37 a 0,59, I2=0%, p=0,67; evidencia con baja seguridad) y mostró resultados controvertidos para el dolor en comparación con el grupo control activo (evaluación cualitativa). Se concluyó que la EENM indujo un aumento de la fuerza muscular en pacientes con osteoartritis, pero no se encontraron diferencias en los resultados de función y dolor en comparación con el grupo control activo. Debido a la incertidumbre de la evidencia, se necesitan más estudios sobre el tema.

https://doi.org/10.1590/1809-2950/20028528042021

15.

[SciELO Preprints] - His and hers: visions and narratives in a Brazilian unit of the Unified Health System (SUS)
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Jurberg, Claudia Sousa, Camila Pereira Belisário de Russomano , Fábio Bastos

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Publication date: 2021-05-25

Abstract: En Pt

This article tries to understand the intersections and differences of narratives among health professionals, users of a highly complex institution within the Unified Health System (SUS) and mothers of children with complex health conditions; also reflects on actions that can contribute to a better communication among these two actors and the formulation of guiding policies for this dialogical exchange in a more effective and efficient way. Focus groups and semi-structured interviews were carried out, totaling 36 participants, including doctors, nurses, social workers, managers, cleaning professionals, front desks and users/mothers of children under treatment at this institution in Rio de Janeiro, during a six-month period. The results were treated from a qualitative-quantitative perspective using the MAXQDA® software, which supported the identification of synergies and antagonisms among the collected narratives, pointing to three main categories of narratives: communication flow between actors; the perception about the institution, including care aspects; and feelings about health, illness and death. As perspectives, we believe the results can be inspiring when reflecting on Social Determinants in Health and SUS.

This articlenbsp;triesnbsp;to understand the intersections and differencesnbsp;of narratives amongnbsp;health professionals,nbsp;users of anbsp;highly complex institution within the Unified Health Systemnbsp;(SUS)nbsp;andnbsp;mothers of children with complex health conditions; alsonbsp;reflectsnbsp;on actions that can contribute to a better communicationnbsp;amongnbsp;these two actors and the formulation of guiding policies for this dialogical exchange in a more effective and efficient way. Focus groups and semi-structured interviews were carried out, totaling 36 participants, including doctors, nurses, social workers, managers, cleaning professionals,nbsp;front desksnbsp;and users/mothersnbsp;of children undernbsp;treatment at this institution in Rio de Janeiro,nbsp;during a six-month period. The results were treated from a qualitative-quantitative perspective using the MAXQDA® software, whichnbsp;supported the identification ofnbsp;synergies and antagonisms among the collected narratives, pointing to three main categories of narratives: communicationnbsp;flownbsp;between actors;nbsp;thenbsp;perceptionnbsp;aboutnbsp;the institution, includingnbsp;care aspects; and feelings about health, illness and death. As perspectives, we believe the results can be inspiring when reflecting on Social Determinants in Health and SUS.

https://doi.org/10.1590/SciELOPreprints.2374

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