ABSTRACT The need for studies that allow the use of brackish water in irrigated agriculture and the socioeconomic importance of melon cultivation in Brazil, especially for the Northeast region, which concentrates most of the national production and faces problems with the availability of good quality water for irrigation, motivated the present study. In this context, the objective of present study was to evaluate the growth, production and fruit quality of the ‘Goldex’ (yellow-type hybrid F1) melon under salt stress conditions. The experiment was performed in a completely randomized design, with two salinity levels of irrigation water (0.8 and 4.0 dS m-1) and eight evaluation times (52, 54, 56, 58, 60, 62, 64, and 66 days after transplanting). Variables of plant growth and development, production and quality of melon fruits were evaluated throughout the cycle. Plants had delayed growth characteristics and less development with the increase in irrigation water salinity, showing reductions of more than 20% in shoot dry weight, leaf area, number of branches and length of secondary branches and 16.7% in length of the main branch. In addition, salinity caused a delay in fruit development and a 16% reduction in final fruit weight, without significantly modifying carbohydrate and total soluble solids contents. Along the development, there was an increase in the total soluble solids content of the fruits, especially due to the increment of sucrose at the final stages of development.

RESUMO A necessidade de estudos que possibilitem a utilização de águas salobras na agricultura irrigada e a importância socioeconômica da cultura do melão no Brasil, especialmente para a região Nordeste, que concentra a maior parte da produção nacional e apresenta problemáticas com disponibilidade de água de boa qualidade para irrigação, norteou o presente estudo. Nesse contexto, o objetivo do presente estudo foi avaliar o crescimento das plantas, a produção e a qualidade de frutos do híbrido de melão amarelo ‘Goldex’ (híbrido F1 tipo amarelo) sob condições de estresse salino. A pesquisa foi conduzida em delineamento inteiramente casualizado, contendo dois níveis de salinidade da água de irrigação (0,8 e 4,0 dS m-1) e oito épocas de avaliação (52, 54, 56, 58, 60, 62, 64 e 66 dias após o transplantio). Foram avaliadas variáveis de crescimento e desenvolvimento das plantas, de produção e de qualidade dos frutos de melão ao longo do ciclo. As plantas tiveram as características de crescimento retardadas e menor desenvolvimento em função do aumento da salinidade da água de irrigação, apresentando redução superior a 20% para a o peso seco da parte aérea, área foliar, número de ramos, comprimento de ramos secundários e 16,7% para o comprimento do ramo principal. Além disso, a salinidade provocou atraso no desenvolvimento dos frutos e redução de 16% no seu peso final, sem modificar significativamente os teores de carboidratos e sólidos solúveis totais. Ao longo do desenvolvimento houve aumento no teor de sólidos solúveis totais dos frutos, especialmente em função do acréscimo de sacarose nos estádios finais de desenvolvimento.

This is a multicenter, cross-sectional study carried out with students regularly enrolled in undergraduate courses at eight Brazilian IFES. Data collection was conducted between October 2021 and February 2022 using an online self-completed questionnaire, which addressed sociodemographic and academic characteristics, lifestyle habits, and health conditions. Symptoms of anxiety and depression were assessed using the Depression, Anxiety, and Stress Scale-21 (DASS-21). Variables were analyzed descriptively using frequency distribution and Pearson’s chi-square test. To estimate the prevalence of symptoms of anxiety and depression, the proportion and 95% confidence interval (95%CI) were used. The level of adopted statistical significance was 5%.

RESUMO Objetivo: Analisar as prevalências de acidentes de trabalho, segundo variáveis sociodemográficas e ocupacionais, em 2013 e 2019. Métodos: Estudo transversal utilizando dados da Pesquisa Nacional de Saúde (PNS) 2013 e 2019. Avaliou-se os acidentes de trabalho típico (AT), de descolamento (AD) e de trabalho totais (ATT). As prevalências e os intervalos de confiança de 95% (IC95%) de ATT em 2013 e 2019 foram estimadas segundo as variáveis explicativas, unidades da Federação e capitais. Em 2019, foram calculadas as prevalências e IC95% segundo variáveis explicativas e razões de prevalência (RP) bruta e ajustada por sexo e faixa etária. Resultados: A prevalência de ATT passou de 4,96% (IC95% 4,55–5,38) em 2013 para 4,13% (IC95% 3,80–4,46) em 2019. Em 2013, o Pará liderou em prevalência de ATT e, em 2019, a maior prevalência foi em Mato Grosso. As prevalências de AT e AD em 2019 foram, respectivamente, 2,64% (IC95% 2,37–2,91) e 1,60% (IC95% 1,40–1,80). Em 2019, as prevalências para ATT foram mais elevadas para homens (RP: 1,92; IC95% 1,62–2,27); faixa etária de 18 a 29 anos (RP: 2,71; IC95% 1,99–3,68); pessoas com ensino fundamental completo/médio incompleto (RP: 2,09; IC95% 1,57–2,78); e pessoas de cor preta (RP: 1,43; IC95% 1,12–1, 84), e menor em pessoas sem carteira de trabalho (RP: 0,77; IC95% 0,66–0,90). AT foi maior na zona rural (RP: 1,32; IC95% 1,09–1,60). Conclusão: Houve redução dos ATT entre 2013 e 2019. Homens, jovens, pretos e indivíduos com menor escolaridade, trabalhadores da zona rural, apresentaram maiores prevalências de AT em 2019, demonstrando uma relação dos processos saúde-doença-acidente.

ABSTRACT Objective: To analyze the prevalence of work-related accidents, according to sociodemographic and occupational variables, in 2013 and 2019. Methods: Cross-sectional study using data from the National Survey of Health (PNS) 2013 and 2019. Typical work accidents (WA), commuting accidents (CA), and Total Work Accidents (TWA) were evaluated. Prevalence values and 95% confidence intervals (95%CI) of TWA in 2013 and 2019 were estimated according to the explanatory variables and for Federative Units and capitals. In 2019, the prevalence and 95%CI according to explanatory variables were estimated using prevalence ratios (PR), both crude and adjusted for sex and age group. Results: TWA prevalence decreased from 4.96% (95%CI 4.55–5.38) in 2013 to 4.13% (95%CI 3.80–4.46) in 2019. In 2013, the state of Pará prevailed in TWA, and the state of Mato Grosso in 2019. The prevalence of WA and CA in 2019 were: 2.64% (95%CI 2.37–2.91) and 1.60% (95%CI 1.40–1.80). In 2019, the prevalence for TWA were higher for men (PR: 1.92; 95%CI 1.62–2.27); in the 18-29 age group (PR: 2.71; 95%CI 1.99–3.68); people with elementary school and some high school (PR: 2.09; 95%CI 1.57–2.78); and Black individuals (PR: 1.43; 95%CI 1.12–1.84). People without formal employment contract had a lower prevalence of TWA (PR: 0.77; 95%CI 0.66–0.90). WA was higher in rural areas (PR: 1.32; 95%CI 1.09–1.60). Conclusion: There was a reduction in TWA between 2013 and 2019. Men, young people, Black people, and individuals with lower level of education, residents in rural areas had higher prevalence of WA in 2019, demonstrating a relationship between health-disease-accident processes.

Abstract This work aimed to characterize some of the bioactive compounds of Eugenia punicifolia (Kunth) DC. fruit to enhance the knowledge of its functional potential. Ripe fruits were collected from the restinga of Maricá, in the state of Rio de Janeiro (RJ), Brazil. Bioactive compounds were analyzed by High Performance Liquid Chromatography (HPLC). Ascorbic acid (74.14 mg 100-1 g-1), lycopene (504 µg g-1) and total carotenoids (632 µg g-1) contents were superior to other fruits rich in these compounds. In fact, E. punicifolia fruits are an excellent source of carotenoids and can be considered a good source of ascorbic acid (vitamin C). Furthermore, its chemical composition has presented phenolic compounds like gallic acid and anthocyanins. Thus, this underutilized Brazilian fruit stands out as a source of bioactive compounds, presenting a good potential as a functional food, especially due to the high content of lycopene.

Resumo Este trabalho teve como objetivo caracterizar alguns dos compostos bioativos do fruto da Eugenia punicifolia (Kunth) DC. para aprofundar o conhecimento do seu potencial funcional. Frutos maduros foram coletados da restinga de Maricá-RJ, Brasil. Os compostos bioativos foram analisados por cromatografia líquida de alta eficiência. Os teores de ácido ascórbico (74,14 mg 100-1 g-1), licopeno (504 µg g-1) e carotenoides totais (632 µg g-1) foram superiores aos de outras frutas ricas nesses compostos. Os frutos de E. punicifolia são uma excelente fonte de carotenoides e podem ser considerados uma boa fonte de ácido ascórbico (vitamina C). Além disso, sua composição química apresentou compostos fenólicos, como ácido gálico e antocianinas. Assim, essa fruta brasileira subutilizada se destaca como fonte de compostos bioativos, apresentando um bom potencial como alimento funcional, principalmente devido ao alto teor de licopeno.

Abstract This study shows the results obtained of evaluation and comparison of chemical analysis and ecotoxicity for evaluated the quality of water contaminated with gasoline after Fenton process. The process Fenton was efficient to remove the aromatics organic compounds such as benzene, toluene and xylenes from water contaminated with gasoline. At 90 minutes of reaction time, the concentration measured of aromatics compounds by gas chromatography were less than limit of quantification (0.05mg L-1). This value is in accordance with the limits established by Brazilian legislation for the effluents discharge. On the other hand, analysis of total phenols and dissolved organic carbon demonstrated at 120 minutes that all dissolved organic compound and total phenols are not totally removed even though benzene, toluene and xylenes were almost completely removed. Phytotoxicity tests using Sinapis alba as biological response showed that water contaminated with gasoline are not toxic, however these results was probably influenced by volatilization of aromatics compounds during the assay. Differently, the ecotoxicity using Daphnia magna showed that water contaminated with aromatic compounds is toxic, but after 120 minutes of treatment the toxicity was reduced more than 50%. Then, Daphnia magna was the better bioindicator to evaluate the efficiency of Fenton process since these results were according with response of dissolved organic carbon and total phenol showing the toxicity of intermediates produced during the Fenton process.

Abstract This study evaluated dental students’ perceptions and adherence to an interactive web-based response system in the teaching of Oral and Maxillofacial Pathology. Between 2018 and 2019, students from a single Brazilian dental school used the Poll Everywhere® app to answer questions on subjects taught during an Oral and Maxillofacial Pathology course. At the end of the academic semester, the students completed a questionnaire containing 10 questions regarding the app’s use. The study included 123 students. Regarding the devices used to answer the questions on the app, 117 (95.1%) students used a smartphone and 3 (2.4%) used a laptop. Almost all students (121; 98.4%) agreed that this interactive web-based response system provided the teacher with a better overview of students’ understanding and improved their self-assessment of the acquired knowledge of the subjects. Most students (118; 95.9%) preferred classes using this technology and 122 (99.2%) stated that using the app made them feel more engaged in classes. In addition, all students agreed that the app improved student–teacher interactions. Most students (119; 96.7%) considered the digital interactive method more attractive than the conventional teaching approach, and 99 (80.5%) did not have any negative comments regarding the app. In conclusion, the Poll Everywhere® app provides a more dynamic and attractive educational environment for Oral and Maxillofacial Pathology teaching.

ABSTRACT Objective: To analyze the prevalence of work-related accidents, according to sociodemographic and occupational variables, in 2013 and 2019. Methods: Cross-sectional study using data from the National Survey of Health (PNS) 2013 and 2019. Typical work accidents (WA), commuting accidents (CA), and Total Work Accidents (TWA) were evaluated. Prevalence values and 95% confidence intervals (95%CI) of TWA in 2013 and 2019 were estimated according to the explanatory variables and for Federative Units and capitals. In 2019, the prevalence and 95%CI according to explanatory variables were estimated using prevalence ratios (PR), both crude and adjusted for sex and age group. Results: TWA prevalence decreased from 4.96% (95%CI 4.55–5.38) in 2013 to 4.13% (95%CI 3.80–4.46) in 2019. In 2013, the state of Pará prevailed in TWA, and the state of Mato Grosso in 2019. The prevalence of WA and CA in 2019 were: 2.64% (95%CI 2.37–2.91) and 1.60% (95%CI 1.40–1.80). In 2019, the prevalence for TWA were higher for men (PR: 1.92; 95%CI 1.62–2.27); in the 18-29 age group (PR: 2.71; 95%CI 1.99–3.68); people with elementary school and some high school (PR: 2.09; 95%CI 1.57–2.78); and Black individuals (PR: 1.43; 95%CI 1.12–1.84). People without formal employment contract had a lower prevalence of TWA (PR: 0.77; 95%CI 0.66–0.90). WA was higher in rural areas (PR: 1.32; 95%CI 1.09–1.60). Conclusion: There was a reduction in TWA between 2013 and 2019. Men, young people, Black people, and individuals with lower level of education, residents in rural areas had higher prevalence of WA in 2019, demonstrating a relationship between health-disease-accident processes.

RESUMO Objetivo: Analisar as prevalências de acidentes de trabalho, segundo variáveis sociodemográficas e ocupacionais, em 2013 e 2019. Métodos: Estudo transversal utilizando dados da Pesquisa Nacional de Saúde (PNS) 2013 e 2019. Avaliou-se os acidentes de trabalho típico (AT), de descolamento (AD) e de trabalho totais (ATT). As prevalências e os intervalos de confiança de 95% (IC95%) de ATT em 2013 e 2019 foram estimadas segundo as variáveis explicativas, unidades da Federação e capitais. Em 2019, foram calculadas as prevalências e IC95% segundo variáveis explicativas e razões de prevalência (RP) bruta e ajustada por sexo e faixa etária. Resultados: A prevalência de ATT passou de 4,96% (IC95% 4,55–5,38) em 2013 para 4,13% (IC95% 3,80–4,46) em 2019. Em 2013, o Pará liderou em prevalência de ATT e, em 2019, a maior prevalência foi em Mato Grosso. As prevalências de AT e AD em 2019 foram, respectivamente, 2,64% (IC95% 2,37–2,91) e 1,60% (IC95% 1,40–1,80). Em 2019, as prevalências para ATT foram mais elevadas para homens (RP: 1,92; IC95% 1,62–2,27); faixa etária de 18 a 29 anos (RP: 2,71; IC95% 1,99–3,68); pessoas com ensino fundamental completo/médio incompleto (RP: 2,09; IC95% 1,57–2,78); e pessoas de cor preta (RP: 1,43; IC95% 1,12–1, 84), e menor em pessoas sem carteira de trabalho (RP: 0,77; IC95% 0,66–0,90). AT foi maior na zona rural (RP: 1,32; IC95% 1,09–1,60). Conclusão: Houve redução dos ATT entre 2013 e 2019. Homens, jovens, pretos e indivíduos com menor escolaridade, trabalhadores da zona rural, apresentaram maiores prevalências de AT em 2019, demonstrando uma relação dos processos saúde-doença-acidente.

Abstract The genus Baruscapillaria Moravec, 1982 has six valid species recorded in birds Phalacrocoracidae, namely Baruscapillaria appendiculata Freitas, 1933, B. spiculata Freitas, 1933, B. carbonis (Dubinin & Dubinina, 1940), B. jaenschi (Johnston & Mawson, 1945), B. phalacrocoraxi (Borgarenko, 1975) and B. rudolphii Moravec, Scholz and Našincová, 1994. Helminthological tests carried out on cormorants of the species Phalacrocorax brasilianus (Gmelin), a migratory bird that occurs in the northeast of the State of Pará, Brazil, demonstrate B. appendiculata parasitizing the cloaca of these birds, through light microscopy, scanning electron microscopy and molecular biology. These studies allowed a redescription of males and females of this nematode in these hosts and in this geographical area through integrative taxonomy. The occurrence of lesions in the cloaca caused by this nematode parasite was registered using histological analysis. This is a new geographic report for this nematode.

Resumo O gênero Baruscapillaria Moravec, 1982 possui seis espécies válidas registradas em aves Phalacrocoracidae, sendo Baruscapillaria appendiculata Freitas, 1933, B. spiculata Freitas, 1933, B. carbonis (Dubinin & Dubinina, 1940), B. jaenschi (Johnston & Mawson, 1945), B. phalacrocoraxi (Borgarenko, 1975) e B. rudolphii Moravec, Scholz & Našincová, 1994. Exames helmintológicos realizados em mergulhões da espécie Phalacrocorax brasilianus (Gmelin), aves migratórias que ocorrem no nordeste do Estado do Pará, Brasil, demonstram B. appendiculata parasitando a cloaca dessas aves, através de microscopia de luz, microscopia eletrônica de varredura e biologia molecular. Estes estudos permitiram uma redescrição de machos e fêmeas deste nematódeo, neste hospedeiro e nesta área geográfica, através da taxonomia integrativa. Foi registrada a ocorrência de lesões na cloaca causadas pelo parasitismo desse nematódeo, por meio de análise histológica, sendo um novo registro geográfico elw.

Abstract For the first time in Brazil, Contracaecum australe is recorded parasitizing Phalacrocorax brasilianus (Aves, Suliformes, Phalacrocoracidae) from the Marine Extractive Reserve of Soure on Marajó Island, Brazilian Amazon. Its morphology revealed a body with a transversally striated cuticle, smooth or slightly cleft interlabia, lips with auricles, labial papillae, and conspicuous amphids. In males, the presence of the median papilla on the upper lip of the cloaca and spicules that reach almost half of the body of the parasite. These morphological characters, added to the number and distribution of the pre- and postcloacal papillae of the male specimens, and supported by the molecular phylogeny from the analysis of the ITS-1, 5.8S and ITS-2 genes, allowed the identification of these parasites.

Resumo Pela primeira vez no Brasil, Contracaecum australe é registrado parasitando Phalacrocorax brasilianus (Aves, Suliformes, Phalacrocoracidae) da Reserva Extrativista Marinha de Soure na Ilha de Marajó, Amazônia brasileira. Sua morfologia revelou corpo com cutícula estriada transversalmente, interlábios lisos ou levemente fendidos, lábios com aurículas, papilas labiais e anfídeos conspícuos. Nos machos, observa-se a presença da papila mediana no lábio superior da cloaca e espículos que atingem quase a metade do corpo do parasito. Esses caracteres morfológicos, somados ao número e distribuição das papilas pré e pós-cloacais dos espécimes machos, e apoiados pela filogenia molecular a partir da análise dos genes ITS-1, 5.8S e ITS-2, permitiram a identificação desses parasitos.

ABSTRACT: Porcine enzootic pneumonia (PES), mainly caused by the bacteria Mycoplasma hyopneumoniae, is the main cause of respiratory problems in pigs. Infection by M. hyopneumoniae leads to production losses and the predisposition of affected animals to secondary infections, which may result in the condemnation of carcasses and organs due to lung lesions at the time of slaughter. The objective of the research was to evaluate the infection by M. hyopneumoniae in pigs submitted to slaughter in São Luís Island/MA, using molecular and histopathological diagnostic methods. One hundred fifty lung samples were collected from inspected (n=65) and non-inspected (n=85) slaughter pigs on São Luís Island, Maranhão, from July 2019 to August 2021. Of the 150 DNA samples collected, 121 showed an amplified product for Cyt B in the PCR assay. Thus, 121 samples were submitted to qPCR of M. hyopneumoniae, of which 44 (36.36%) showed positive results. The mean amount of bacterial load ranged from 1.20 × 101 to 7.20 × 104, with a mean of 1.73 × 104 copies. Of the reagent samples, 81.81% (36 samples) were obtained from non-inspected slaughter, while 18.18% (8 samples) were obtained from slaughterhouses. In the histopathological analysis, 44 positive qPCR samples were evaluated, of which 28 (63.63%) presented results compatible with the main inflammatory process associated with the presence of M. hyopneumoniae, that is, bronchial-associated lymphoid tissue hyperplasia (BALT). Three samples that showed the highest bacterial load (qPCR: 5.63 × 10³, 2.19 × 104 and 7.23 × 104) showed more evident lesions in this study. The microscopic findings associated with the quantifications indicated a relationship between the amount of bacterial load and the presence of microscopic lesions; higher bacterial load in lung tissue is associated with increased histopathologic staining for BALT hyperplasia. In conclusion, the results point to the circulation of the etiological agent in the sampled animals and the need for preventive measures on pig farms in Maranhão with the involvement of producers, sanitary defense and inspection agencies.

RESUMO: A pneumonia enzoótica suína (PES), causada principalmente pela bactéria Mycoplasma hyopneumoniae, é a principal causa de problemas respiratórios em suínos. A infecção por M. hyopneumoniae leva a perdas produtivas e a predisposição dos animais acometidos a infecções secundárias, o que pode resultar em condenação de carcaças e órgãos por lesões pulmonares no momento do abate. O objetivo da pesquisa foi avaliar a infecção por M. hyopneumoniae em suínos submetidos ao abate na Ilha de São Luís, por meio de métodos diagnósticos moleculares e histopatológicos. Para isso, foram coletadas 150 amostras de pulmão de suínos de abate inspecionado (n=65) e não inspecionado (n=85) na Ilha de São Luís/Maranhão, no período de julho de 2019 a agosto de 2021. Das 150 amostras de DNA coletadas, 121 apresentaram produto amplificado para Cyt B no ensaio de PCR. Assim, 121 amostras foram submetidas à qPCR de M. hyopneumoniae, das quais 44 (36,36%) apresentaram resultados positivos. A quantidade média de carga bacteriana variou de 1,20 × 101 a 7,20 × 104, com média de 1,73 × 104 cópias. Das amostras reagentes, 81,81% (36 amostras) foram obtidas de abate não inspecionado, enquanto 18,18% (8 amostras) foram obtidas em abatedouro. Na análise histopatológica, foram avaliadas 44 amostras positivas para qPCR, das quais 28 (63,63%) apresentaram resultados compatíveis com o principal processo inflamatório associado à presença de M. hyopneumoniae, ou seja, hiperplasia do tecido linfóide associado ao brônquio (BALT). Três amostras que apresentaram maior carga bacteriana (qPCR: 5,63 × 10³, 2,19 × 104 e 7,23 × 104) foram mais evidentes neste estudo. Os achados microscópicos associados às quantificações indicaram uma relação entre a quantidade de carga bacteriana e a presença de lesão microscópica; a maior carga bacteriana no tecido pulmonar está associada a maior alteração histopatológica para hiperplasia BALT. Em conclusão, os resultados obtidos sinalizam para a circulação do agente etiológico nos animais amostrados e a necessidade de medidas preventivas nas criações de suínos do estado do Maranhão com envolvimento dos produtores, órgãos de defesa sanitária e inspeção.

Abstract Capillaria Zeder, 1800, parasitizes the organs and tissues of several hosts, including the domestic duck Cairina moschata (Linnaeus). This article describes a new species of Capillaria in domestic ducks identified based on morphological studies and molecular analyses of the ribosomal RNA gene. Thirty-eight specimens of C. moschata from the municipality of Soure, Marajó Island, Pará, Brazil. The organs of the birds' digestive tract were analyzed under a stereomicroscope to confirm the parasitic infection, after which the collected nematodes were identified by light microscopy, scanning electron microscopy, and molecular analysis. Capillariids parasitized the intestine and cecum of the examined birds. These parasites had three bacillary bands and a pair of elongated precloacal papillae on the tail. Phylogenetic analysis indicated that the new species formed a sister clade with Capillaria spinulosa (Linstow, 1890), as described in Indonesia and Japan. Based on morphological distinctions and molecular data, Capillaria cairina n. sp. can be considered a new parasite species of C. moschata in the Brazilian Amazon.

Resumo Capillaria Zeder, 1800 parasitam órgãos e tecidos de diversos hospedeiros, incluindo o pato doméstico Cairina moschata (Linnaeus). Este artigo descreve uma nova espécie de Capillaria em patos domésticos, identificada com base em estudos morfológicos e análises moleculares do gene do RNA ribossomal. Trinta e oito espécimes de C. moschata oriundo dos no município de Soure, Ilha de Marajó, Pará, Brasil. Os órgãos do aparelho digestivo das aves foram analisados em estereomicroscópio para confirmar a infecção parasitária. Após, os nematódeos coletados foram identificados por microscopia de luz, microscopia eletrônica de varredura e análises moleculares. Os capilarídeos parasitaram intestino e ceco das aves examinadas. Esses parasitas apresentaram três bandas bacilares e um par de papilas pré-cloacais alongadas na cauda. A análise filogenética indicou que a nova espécie formou um clado irmão com Capillaria spinulosa (Linstow, 1890), conforme descrito na Indonésia e no Japão. Com base na distinção morfológica e dados moleculares, Capillaria cairina n. sp. pode ser considerada uma nova espécie de parasita de C. moschata na Amazonia brasileira.

Ursolic acid (UA) is being investigated due to its anti-inflammatory potential, and structural modifications can enhance its biological activities. The aim of this study was to evaluate the immunomodulatory effect of the ursolic acid derivatives (UAD) in macrophages and in the carrageenan-induced paw edema model. RAW264.7 cells were cultured in the presence or absence of UA or UAD (1-18). Nitric oxide (NO), nuclear factor kappa B (NF-κB), tumor necrosis factor (TNF), and cellular viability were measured. 30 min before the carrageenan-induced paw edema, the UAD1 and UAD2 (200 mg kg-1) were administered intraperitoneally. The results showed that UAD2-4, UAD7, UAD9-11 had half maximal inhibitory concentration (IC50) greater than 90 µM and were able to reduce NO, NF-κB and TNF production. Moreover, UAD1 and UAD2 reduced paw edema and IL-6 production. In conclusion, the results obtained demonstrated a variation in the response between the derivatives due to the chemical modifications, showing potential to reduce the inflammatory mediators, deserving further investigations.

In these last decades, with the advance of industrialization, the enormous quantity of residue that is discarded by the industry has been generating discussions about eco-efficient solutions. This research has the objective of developing an artificial stone with residue of quartzite and fine quarry gravel (granite), utilizing the vibro-compression vacuum method. The residue was separated in three granulometric ranges with sieving: Large and medium (fine quarry gravel) and fine (quartzite). A statistical treatment was used in the acquired data, utilizing analysis of variance (ANOVA). The characterization was through a physical, mechanical, dilatometric and microstructural analysis. The obtained results classify the material as having high potential to be used for flooring in the civil construction industry, since it has low porosity <0.17% e water absorption < 0.3%, maximum flexural strength > 30 MPa, being able to be utilized in medium and low traffic environments.

Novel civil construction materials based on waste can be an optimal alternative for waste management, reducing its improper disposal while engaging an otherwise discarded material as a raw material in other production processes. This research’s main objective was to develop and characterize two novel artificial stones based on waste glass from bottles and aggregated with epoxy resin (ASG-EP) and polyurethane resin (ASG-PU) from castor oil, respectively, as well as the comparison of the two developed materials. Plates were manufactured with 15% of epoxy or 15% polyurethane resins and 85% of waste glass from bottles. The mixture was molded with a process of 6Hz vibration, 600mmHg of vacuum, and hot compaction at 90ºC for EP and 80ºC for PU. Results evidenced that the development of ASGs based on waste glass from bottles is technically and economically viable.

Abstract The purpose of this article is to analyze the discourse of high school students in favor of healthy eating in the context of English language teaching in a public professional education school. Based on Dialogic Discourse Analysis, a corpus composed of 2 posts on Instagram by high school students enrolled in the technical course of Nutrition and Dietetics who produced verbal-visual texts during an action research with English classes inspired by Historical-Critical Pedagogy is explored. The analysis of the posts reveals that the discourse in favor of healthy eating is interrelated with the technical discourse, the everyday discourse, and the discourse about the consequences of fast food consumption. The analysis also shows that the posts have a negative value emphasis in relation to the consumption of fast food, and, through the pamphlet and the informative poster, they denounce the dangers of unhealthy food choices, also seeking to raise awareness among their interlocutors and promote a change in the social practice of these subjects. It is concluded that English classes inspired by Historical-Critical Pedagogy provide students with opportunities to disseminate discourses in a far-reaching social network, expanding their interlocutors, committing themselves to collaborate for a society that is more aware of its eating habits.

Resumo O objetivo deste artigo é analisar o discurso de estudantes de ensino médio a favor de uma alimentação saudável no contexto de ensino de língua inglesa em uma escola pública de educação profissional. A partir da Análise Dialógica do Discurso, explora-se um corpus composto por duas postagens no Instagram de estudantes do ensino médio integrado ao curso técnico de Nutrição e Dietética que produziram textos verbo-visuais durante uma pesquisa-ação com aulas de inglês inspiradas na Pedagogia Histórico-Crítica. A análise das postagens revela que o discurso a favor de uma alimentação saudável se inter-relaciona com o discurso técnico, o discurso do cotidiano e o discurso sobre as consequências do consumo de fast food. A análise também evidencia que as postagens apresentam uma ênfase valorativa negativa em relação ao consumo de fast food, e, por meio do panfleto e do cartaz informativo, denunciam os perigos de escolhas alimentares não saudáveis, buscando, ainda, conscientizar seus interlocutores e promover uma mudança na prática social desses sujeitos. Conclui-se que as aulas de inglês inspiradas na Pedagogia Histórico-Crítica oportunizam aos estudantes circular discursos em uma rede social de grande alcance, ampliando seus interlocutores, comprometendo-se a colaborar para uma sociedade mais consciente dos seus hábitos alimentares.