Search | SciELO

Abstract Next-generation sequencing (NGS) has altered clinical genetic testing by widening the access to molecular diagnosis of genetically determined rare diseases. However, physicians may face difficulties selecting the best diagnostic approach. Our goal is to estimate the rate of possible molecular diagnoses missed by different targeted gene panels using data from a cohort of patients with rare genetic diseases diagnosed with exome sequencing (ES). For this purpose, we simulated a comparison between different targeted gene panels and ES: the list of genes harboring clinically relevant variants from 158 patients was used to estimate the theoretical rate of diagnoses missed by NGS panels from 53 different NGS panels from eight different laboratories. Panels presented a mean rate of missed diagnoses of 64% (range 14%-100%) compared to ES, representing an average predicted sensitivity of 36%. Metabolic abnormalities represented the group with highest mean of missed diagnoses (86%), while seizure represented the group with lowest mean (46%). Focused gene panels are restricted in covering select sets of genes implicated in specific diseases and they may miss molecular diagnoses of rare diseases compared to ES. However, their role in genetic diagnosis remains important especially for well-known genetic diseases with established genetic locus heterogeneity.

https://doi.org/10.1590/1678-4685-gmb-2021-0061 205 downloads

Relationship between photosynthetic pigments and corn production under nitrogen sources
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Fornari, Ezequiel Zibetti

; Gaviraghi, Lucas

; Basso, Claudir José

; Pinheiro, Marcos Vinícius Marques

; Vian, André Luis

; Santi, Antônio Luis

Pesquisa Agropecuária Tropical

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2020, Volume 50 elocation e63661

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O nitrogênio (N) é um elemento dinâmico no solo. Dessa forma, novas alternativas de fertilização nitrogenada são demandadas, como forma de maximizar a sua eficiência. Aliado a isso, os sensores de vegetação surgem como forma de avaliar e manejar as demandas nutricionais das plantas. Objetivou-se avaliar o efeito de fontes de nitrogênio nos pigmentos fotossintéticos e sua correlação com o rendimento de grãos e biomassa seca em milho. O experimento foi conduzido em blocos casualizados com fontes de nitrogênio (mineral, orgânica e biológica). Avaliaram-se os teores de clorofila a, b e total, bem como de carotenoides. Os índices de clorofila avaliados por ambos os métodos se correlacionaram positivamente entre si e com o rendimento de grãos por planta. A adubação nitrogenada 100 % mineral foi superior, quando comparada com os demais tratamentos, com incrementos de até 44 %. Verificou-se relação positiva entre os métodos de determinação e a estimativa dos teores de clorofila. O rendimento de grãos por planta apresentou os maiores valores quando se utilizou a fonte de adubação 100 % mineral, apresentando incrementos acima de 10 %, em relação às demais fontes, com gasto de US$ 89.77 com o fertilizante e ganho acima de US$ 538.60 para o rendimento de grãos. Verificou-se correlação positiva entre os pigmentos fotossintetizantes avaliados por ambos os métodos e o rendimento de grãos por planta. Recomendam-se ambos os métodos para a avaliação das concentrações de clorofila.

ABSTRACT Nitrogen (N) is a dynamic element in the soil, so new nitrogen fertilization alternatives are required as a way of maximizing its efficiency. Besides, vegetation sensors are a way to assess and manage the nutritional demands of plants. This study aimed to evaluate the effect of nitrogen sources on photosynthetic pigments and their correlation with corn grain yield and dry biomass. The experiment was carried out in a randomized block design with nitrogen sources (mineral, organic and biological). Contents of chlorophyll a, b and total, as well as carotenoids, were evaluated. The chlorophyll indices evaluated by both methods were positively correlated with each other and with the grain yield per plant. Nitrogen fertilization 100 % mineral was superior, when compared to the other treatments, with increments of up to 44 %. There was a positive relationship between the methods of determining and estimating the chlorophyll contents. The grain yield per plant showed the highest values when using the 100 % mineral fertilizer source, with increments above 10 %, in relation to the other sources, spending US$ 89.77 on fertilizer and earning over US$ 538.60 on grain yield. There was a positive correlation between the photosynthetic pigments obtained by both methods and grain yield per plant. Both methods are recommended for the evaluation of chlorophyll concentrations.

https://doi.org/10.1590/1983-40632020v5063661 423 downloads

Assessment of neuropharmacological potential of low molecular weight components extracted from Rhinella schneideri toad poison
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Baldo, Mateus Amaral

; Cunha, Alexandra Olimpio Siqueira

; Godoy, Lívea Dornela

; Liberato, José Luiz

; Yoneda, Juliana Sakamoto

; Fornari-Baldo, Elisa Correa

; Ciancaglini, Pietro

; Santos, Wagner Ferreira dos

; Arantes, Eliane Candiani

Journal of Venomous Animals and Toxins including Tropical Diseases

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2019, Volume 25 elocation e148418

Abstract: En | Text: En | PDF: En

Abstract Background: Studies on toad poison are relevant since they are considered a good source of toxins that act on different biological systems. Among the molecules found in the toad poison, it can be highlighted the cardiotonic heterosides, which have a known mechanism that inhibit Na+/K+-ATPase enzyme. However, these poisons have many other molecules that may have important biological actions. Therefore, this work evaluated the action of the low molecular weight components from Rhinella schneideri toad poison on Na+/K+-ATPase and their anticonvulsive and / or neurotoxic effects, in order to detect molecules with actions of biotechnological interest. Methods: Rhinella schneideri toad (male and female) poison was collected by pressuring their parotoid glands and immediately dried and stored at -20 °C. The poison was dialysed and the water containing the low molecular mass molecules (< 8 kDa) that permeate the dialysis membrane was collected, frozen and lyophilized, resulting in the sample used in the assays, named low molecular weight fraction (LMWF). Na+/K+ ATPase was isolated from rabbit kidneys and enzyme activity assays performed by the quantification of phosphate released due to enzyme activity in the presence of LMWF (1.0; 10; 50 and 100 µg/mL) from Rhinella schneideri poison. Evaluation of the L-Glutamate (L-Glu) excitatory amino acid uptake in brain-cortical synaptosomes of Wistar rats was performed using [3H]L-glutamate and different concentration of LMWF (10-5 to 10 µg/µL). Anticonvulsant assays were performed using pentylenetetrazole (PTZ) and N-methyl-D-aspartate (NMDA) to induce seizures in Wistar rats (n= 6), which were cannulated in the lateral ventricle and treated with different concentration of LMWF (0.25; 0.5; 1.0; 2.0; 3.0 and 4.0 µg/µL) 15 min prior to the injection of the seizure agent. Results: LMWF induced a concentration-dependent inhibition of Na+/K+-ATPase (IC50% = 107.5 μg/mL). The poison induces an increased uptake of the amino acid L-glutamate in brain-cortical synaptosomes of Wistar rats. This increase in the L-glutamate uptake was observed mainly at the lowest concentrations tested (10-5 to 10-2 µg/µL). In addition, this fraction showed a very relevant central neuroprotection on seizures induced by PTZ and NMDA. Conclusions: LMWF from Rhinella schneideri poison has low molecular weight compounds, which were able to inhibit Na+/K+-ATPase activity, increase the L-glutamate uptake and reduced seizures induced by PTZ and NMDA. These results showed that LMWF is a rich source of components with biological functions of high medical and scientific interest.

https://doi.org/10.1590/1678-9199-jvatitd-1484-18 1080 downloads

Improving the Radiopacity of Calcium Aluminate Cement Based Blends
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira, Ivone Regina de

; Vieira, Gabriela do Vale

; Santos, Kennedy Wallace dos

; Raniero, Leandro José

; Castro-Raucci, Larissa Moreira

; Oliveira, Paulo Tambasco de

; Fornari, Celso Israel

; Pandolfelli, Victor Carlos

Materials Research

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2018, Volume 21 N. 2 elocation e20170599

Abstract: En | Text: En | PDF: En

The radiopacity of CAC-based compositions containing additives (ZnO, Ag and Bi2O3) was evaluated by optical density measurements, cold crushing strength, apparent porosity, pore size distribution, in vitro apatite-formation ability (bioactivity) and cell viability. The bioactivity was assessed via pH and calcium concentration measurements in simulated body fluid (SBF) for samples previously treated or not with sodium silicate (SS) solution. The surface of the samples after treatment was analyzed by scanning electron microscopy, energy dispersive X-ray analysis and confocal Raman spectroscopy. Cell viability was evaluated by MTT and alkaline phosphatase (ALP) activity. Radiopacity results confirmed that compositions containing ZnO-Ag (25:1 wt%) and ZnO-Bi2O3 (15:10 wt%) presented suitable values of radiopacity (> 3 mmAl). The identification of calcium and mainly phosphorus by EDX, highlighted the generation of an apatite-like layer on the compositions' surface after immersion in SBF or SBF/SS. CAC-blend containing 25 wt% ZnO, ZnO-Ag and ZnO-Bi2O3 presented slightly lower cell viability compared to the positive control.

https://doi.org/10.1590/1980-5373-mr-2017-0599 650 downloads

BLOQUEO INFRACLAVICULAR CON VENTANA ACÚSTICA AXILAR: Resultados preliminares.
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Stinga, José Luis

; Fornari, Gustavo García

Anestesia Analgesia Reanimación

Journal Metrics
- Sobre o periódico
- SciELO Analytics

nov 2017, Volume 30 N. spe Pages 21 - 21

Abstract: Es | Text: Es | PDF: Es

Resumen Introducción: El abordaje coracoideodel bloqueo infraclavicularecoguiado condiciona la visualización de la aguja debido al grado de inclinación y lapresencia de sombra acústica ósea. Objetivos: 1) Determinar el grado de visualización de la agujaobjetivado por reverberación, mediante escala descriptiva (óptima, regular, dificultosa) definida por el operador; 2) Medición del dolor por evaluador independiente,en 60 y 120 minutos del postoperatorio, mediante escala visual numérica Materiales y Métodos: Se realizó un estudio descriptivo, en 30 pacientes con indicación de bloqueo del plexo braquial en cirugías de miembro superior. En todos los casos, se realizó anestesia combinada, mediante un bloqueo infraclavicularecoguiado con ventana acústica axilar. Análisis estadístico: La variable categórica fue analizada mediante test de chi cuadrado. Se evaluó el cambio del dolor postoperatorio por escala visual numérica, con modelo lineal generalizado para medidas repetidas en los tiempos 60 y 120 minutos. Resultados: Se visualizó reverberación en forma óptima en el 100% de los casos, registrándose una escala de dolor por escala visual numérica de ceroa los60 y 120 minutos del postoperatorio en todos los pacientes evaluados. Discusión: La dificultad de la visualización de la aguja en el abordaje coracoideo fuedescripta en numerosas publicaciones, careciendo la literatura de trabajos previos que evalúen este abordaje. Conclusiones: El bloqueo infraclavicular mediante este novedoso abordaje permitiría superar la limitación del tradicional coracoideo, asegurando una adecuada visualización de la aguja con resultados óptimos para controlar el dolor postoperatorio. Estudios prospectivos comparando ambas técnicas deberían realizarse para comprobar estos hallazgos.

386 downloads

3rd Guideline for Perioperative Cardiovascular Evaluation of the Brazilian Society of Cardiology
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Gualandro, Danielle Menosi

; Yu, Pai Ching

; Caramelli, Bruno

; Marques, André Coelho

; Calderaro, Daniela

; Fornari, Luciana Savoy

; Pinho, Claudio

; Feitosa, Alina Coutinho Rodrigues

; Polanczyk, Carisi Anne

; Rochitte, Carlos Eduardo

; Jardim, Carlos

; Vieira, Carolina L. Z.

; Nakamura, Debora Y. M.

; Iezzi, Denise

; Schreen, Dirk

; Adam, Eduardo Leal

; D’Amico, Elbio Antonio

; Lima, Emerson Q. de

; Burdmann, Emmanuel de Almeida

; Mateo, Enrique Indalecio Pachón

; Marcondes-Braga, Fabiana Goulart

; Machado, Fabio S.

; Paula, Flavio J. de

; Carmo, Gabriel Assis Lopes do

; Feitosa-Filho, Gilson Soares

; Prado, Gustavo Faibischew

; Lopes, Heno Ferreira

; Fernandes, João R. C.

; Lima, José J. G. de

; Sacilotto, Luciana

; Drager, Luciano Ferreira

; Vacanti, Luciano Janussi

; Rohde, Luis Eduardo Paim

; Prada, Luis F. L.

; Gowdak, Luis Henrique Wolff

; Vieira, Marcelo Luiz Campos

; Monachini, Maristela Camargo

; Macatrão-Costa, Milena Frota

; Paixão, Milena Ribeiro

; Oliveira Junior, Mucio Tavares de

; Cury, Patricia

; Villaça, Paula R.

; Farsky, Pedro Silvio

; Siciliano, Rinaldo F.

; Heinisch, Roberto Henrique

; Souza, Rogerio

; Gualandro, Sandra F.M.

; Accorsi, Tarso Augusto Duenhas

; Mathias Júnior, Wilson

Arquivos Brasileiros de Cardiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2017, Volume 109 N. 3 Pages 1 - 104

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20170140 100302 downloads

Treatment of congenital clubfoot using Ponseti method
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Chueire, Alceu José Fornari Gomes

; Carvalho Filho, Guaracy

; Kobayashi, Otto Yosuke

; Carrenho, Leonardo

Revista Brasileira de Ortopedia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2016, Volume 51 N. 3 Pages 313 - 318

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO: Analisar quantitativa e qualitativamente os resultados do tratamento do pé torto congênito com seguimento médio de 4,6 anos. MÉTODOS: Foram analisados 26 pacientes que fizeram tratamento pelo método de Ponseti, total de 39 pés. A média da idade do início do tratamento foi 5,65 meses. O tempo de seguimento após a tenotomia do tendão de Aquiles foi em média de 4,6 anos. Foram excluídos pacientes com pé torto secundário. Foram analisados dados epidemiológicos e mensurações radiográficas do ângulo de Kite e aplicados questionário de satisfação e questionário de Laaveg. RESULTADOS: Dos 26 pacientes tratados, um apresentou recidiva da deformidade, foi necessário retornar ao início do tratamento. A pontuação média do questionário e do exame físico foi de 89,76, resultado considerado bom; 99% dos pacientes responderam que os pés nunca doem ou doem somente aos grandes esforços; 88% responderam que o pé não limita as atividades; 96% responderam que estão muito satisfeitos ou satisfeitos com os resultados do tratamento. A média do ângulo de Kite na incidência anteroposterior foi de 28,14° e no perfil 26,11°. CONCLUSÃO: O tratamento para pé torto congênito idiopático pelo método Ponseti é o que traz melhores resultados associado a menor lesão de partes moles, o que confirma a eficácia e a boa reprodutibilidade do método.

ABSTRACT OBJECTIVE: To quantitatively and qualitatively analyze the results from treatment of congenital clubfoot with a mean follow-up of 4.6 years. METHODS: 26 patients who underwent treatment by means of the Ponseti method were analyzed (total of 39 feet). The mean age at the start of the treatment was 5.65 months. The mean length of the follow-up subsequent to tenotomy of the Achilles tendon was 4.6 years. Patients with secondary clubfoot were excluded. Epidemiological data, radiographic measurements on the Kite angle and data from a satisfaction questionnaire and the Laaveg questionnaire were analyzed. RESULTS: Among the 26 patients treated, one presented recurrence of the deformity and had to return to the beginning of the treatment. The mean score from the questionnaire and physical examination was 89.76 points, and this result was considered good. 99% of the patients responded that their feet never hurt or hurt only upon great activity; 88% said that their feet did not limit their activities; and 96% said that they were very satisfied or satisfied with the results from the treatment. The mean Kite angle in anteroposterior view was 28.14° and it was 26.11° in lateral view. CONCLUSION: Treatment for idiopathic congenital clubfoot by means of the Ponseti method brings better results together with less soft-tissue injury, thus confirming the effectiveness and good reproducibility of this method.

https://doi.org/10.1016/j.rboe.2015.06.020 22571 downloads

Overactive bladder – 18 years – Part II
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Truzzi, Jose Carlos

; Gomes, Cristiano Mendes

; Bezerra, Carlos A.

; Plata, Ivan Mauricio

; Campos, Jose

; Garrido, Gustavo Luis

; Almeida, Fernando G.

; Averbeck, Marcio Augusto

; Fornari, Alexandre

; Salazar, Anibal

; Dell’Oro, Arturo

; Cintra, Caio

; Sacomani, Carlos Alberto Ricetto

; Tapia, Juan Pablo

; Brambila, Eduardo

; Longo, Emilio Miguel

; Rocha, Flavio Trigo

; Coutinho, Francisco

; Favre, Gabriel

; Garcia, José Antonio

; Castaño, Juan

; Reyes, Miguel

; Leyton, Rodrigo Eugenio

; Ferreira, Ruiter Silva

; Duran, Sergio

; López, Vanda

; Reges, Ricardo

International braz j urol

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2016, Volume 42 N. 2 Pages 199 - 214

Abstract: En | Text: En | PDF: En

ABSTRACT Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics – pillars of the overactive bladder pharmacotherapy – started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning – as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder – 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder.

https://doi.org/10.1590/S1677-5538.IBJU.2015.0367 2297 downloads

Overactive bladder – 18 years – part I
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Truzzi, Jose Carlos

; Gomes, Cristiano Mendes

; Bezerra, Carlos A.

; Plata, Ivan Mauricio

; Campos, Jose

; Garrido, Gustavo Luis

; Almeida, Fernando G.

; Averbeck, Marcio Augusto

; Fornari, Alexandre

; Salazar, Anibal

; Dell'Oro, Arturo

; Cintra, Caio

; Sacomani, Carlos Alberto Ricetto

; Tapia, Juan Pablo

; Brambila, Eduardo

; Longo, Emilio Miguel

; Rocha, Flavio Trigo

; Coutinho, Francisco

; Favre, Gabriel

; Garcia, José Antonio

; Castaño, Juan

; Reyes, Miguel

; Leyton, Rodrigo Eugenio

; Ferreira, Ruiter Silva

; Duran, Sergio

; López, Vanda

; Reges, Ricardo

International braz j urol

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2016, Volume 42 N. 2 Pages 188 - 198

Abstract: En | Text: En | PDF: En

ABSTRACT Abstract: Overactive bladder syndrome is one of the lower urinary tract dysfunctions with the highest number of scientific publications over the past two decades. This shows the growing interest in better understanding this syndrome, which gathers symptoms of urinary urgency and increased daytime and nighttime voiding frequency, with or without urinary incontinence and results in a negative impact on the quality of life of approximately one out of six individuals – including both genders and almost all age groups. The possibility of establishing the diagnosis just from clinical data made patients' access to specialized care easier. Physiotherapy resources have been incorporated into the urological daily practice. A number of more selective antimuscarinic drugs with consequent lower adverse event rates were released. Recently, a new class of oral drugs, beta-adrenergic agonists has become part of the armamentarium for Overactive Bladder. Botulinum toxin injections in the bladder and sacral neuromodulation are routine modalities of treatment for refractory cases. During the 1st Latin-American Consultation on Overactive Bladder, a comprehensive review of the literature related to the evolution of the concept, epidemiology, diagnosis, and management was conducted. This text corresponds to the first part of the review Overactive Bladder 18-years.

https://doi.org/10.1590/S1677-5538.IBJU.2015.0365 3261 downloads

10.

Validation of the Brazilian version of the Spinal Cord Independence Measure III
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Riberto, Marcelo

; Tavares, Daniel Amorim

; Rimoli, José Ragide Jamal

; Castineira, Carolina Pastorin

; Dias, Rodrigo Vasconcelos

; Franzoi, Ana Cristina

; Vall, Janaina

; Lopes, Kathya Augusta Thomé

; Chueire, Regina Helena M Fornari

; Battistella, Linamara Rizzo

Arquivos de Neuro-Psiquiatria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2014, Volume 72 N. 6 Pages 439 - 444

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Introdução : A Medida de Independência da Medula Espinhal III (SCIM III) avalia especificamente a funcionalidade de indivíduos com lesões da medula espinhal. Objetivo : Traduzir e validar a versão brasileira da SCIM III. Método : A SCIM III foi traduzida, contra-traduzida e adaptada para o idioma português brasileiro. Dois entrevistadores avaliaram 83 indivíduos com lesões da medular espinhal em sete centros de reabilitação colaboradores. A Medida de Independência Funcional (FIM™) e índices motor e sensitivo da ASIA também foram usados. Após seis meses, os sujeitos foram reavaliados com os mesmo instrumentos. Resultados : Os avaliadores entenderam claramente a versão brasileira da SCIM III. O coeficiente de correlação intraclasse (ICC) inter-examinadores foi 0,918, e de teste-reteste foi 0,991. Após seis meses, a variação de ganhos na FIM™ correlacionou-se positivamente com os ganhos da SCIM III. Conclusão : A versão brasileira da SCIM III é de fácil entendimento, apresenta boas propriedades psicométricas e é válida.

Introduction : The Spinal Cord Independence Measure (SCIM III) specifically assesses individuals with spinal cord injuries. Objective : To translate and validate the Brazilian version of SCIM III. Method : SCIM III was translated, back-translated and adapted to the Portuguese language. Two interviewers assessed 83 subjects with spinal cord injuries in each one of seven collaborating rehabilitation centers. Functional Independence Measure (FIM™) and ASIA motor and sensory indices were also used. After six months, subjects were re-evaluated with the same instruments. Results : Examiners clearly understood the Brazilian version of SCIM III. Inter-rater intraclass correlation coefficient (ICC) was 0.918, and test-retest ICC was 0.991. After six months, the variation of gains in the FIM™ positively correlated with gains in SCIM III. Conclusion : The Brazilian version of the SCIM III is easy to understand, has good psychometric properties, and is valid.

https://doi.org/10.1590/0004-282X20140066 5737 downloads Cited 1 time in SciELO

11.

Avaliação tomográfica dos pedículos vertebrais no tratamento cirúrgico dos pacientes com escoliose idiopática do adolescente
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Chueire, Alceu Gomes

; Nogueira, Fabiano

; Ono, Allan Hiroshi de Araujo

; Volpi, Mauro dos Santos

; Chueire, Alceu José Fornari

Coluna/Columna

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2012, Volume 11 N. 4 Pages 315 - 317

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

OBJETIVO: Determinar através de cortes tomográficos e reconstrução tridimensional a incidência de mal posicionamento de parafusos em pacientes submetidos ao tratamento cirúrgico da Escoliose idiopática do adolescente. MÉTODOS: Foram analisados exames tomográficos de 8 pacientes, tratados cirurgicamente no Hospital de Base de São José do Rio Preto-SP, realizada instrumentação posterior partindo de T2 /T4 a L4/L5 totalizando 164 parafusos. RESULTADOS: 32,9% (n=54) apresentavam posicionamento com risco potencial,ou seja desvio acima de 2 milímetros, sendo 20,1% (n=33) com invasão lateral, 9,1% (n=15) com invasão medial, 3,6 %(n=6) com invasão anterior. Dos parafusos que ofereciam risco potencial a relação com aspecto da curva foi de 46% (n=25) na concavidade, 35% (n=19) na convexidade e 19% (n=10) em vértebras adjacentes a curva. CONCLUSÃO: Os limites de penetração aceitáveis, assim como os métodos de mensuração ainda não foram padronizados, a técnica "free hand' mostrou-se segura, apesar da violação dos pedículos. A tomografia computadorizada pré-operatória, auxilia no planejamento cirúrgico e na redução das complicações.

OBJECTIVE: To Evaluate by CT scan tridimensional reconstruction, malpositioning of pedicle screws in adolescent idiopathic scoliosis patients. METHODS: It was analyzed CT scan cuts of 8 patients submitted to surgical treatment in Hospital de Base de São José do Rio Preto- SP, which were performed posterior spinal fusion from T2/T4 to L4/L5, 164 screws were inserted. RESULTS: 32,9% (n=54) were malpositioned offering potential risk, which was considered 2mm deviation, 20,1% (n=33) lateral invasion, 9,1% (n=15) medial invasion, 3,6% (n= 6) anterior invasion. From those malpositioned screws 46% (n=25) were in concavity, 35% (n=19) in convexity and 19% (n=10) were nearby curve. CONCLUSION: Acceptable invasion boundaries were not well determined, and also measurements methods are not standardized. The "free hand" technique proved safe, besides pedicle violation. Pre-Op CT Scan showed helpful in surgery planning and avoiding complications.

OBJETIVO: Evaluar mediante tomografía computarizada tridimensional de reconstrucción, una mala posición de los tornillos de pedículo en pacientes con escoliosis idiopática del adolescente. MÉTODOS: Se analizó cortes de tomografía computarizada de 8 pacientes sometidos a tratamiento quirúrgico en el Hospital de Base de São José do Rio Preto-SP, que se llevaron a cabo la fusión vertebral posterior de T2/T4 a L4/L5, 164 tornillos se insertaron. RESULTADOS: 32,9% (n = 54) fueron mal colocados que ofrecen riesgo potencial, que se consideraba una desviación de 2 mm, 20,1% (n = 33), la invasión lateral, el 9,1% (n = 15) invasión medial, 3,6 % (n = 6) la invasión anterior. De los tornillos mal colocados el 46% (n = 25) fueron en la concavidad, el 35% (n = 19) en la convexidad y el 19% (n = 10) se curva cerca. CONCLUSIÓN: Los límites aceptables invasión no se determinaron también, y también los métodos de medición no están estandarizados. La técnica "free hand" resultó segura, además de violación pedículo. Pre-Op CT Scan mostró útil en la cirugía de la planificación y evitar complicaciones.

2682 downloads

12.

Interdisciplinaridade e complexidade no curso de graduação em Administração
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Amboni, Nério

; Andrade, Rui Otávio Bernardes de

; Lima, Arnaldo José de

; Muller, Isabela Regina Fornari

Cadernos EBAPE.BR

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2012, Volume 10 N. 2 Pages 302 - 328

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este artigo tem por objetivo geral discutir as bases, a metodologia de operacionalização e os resultados do programa de integração horizontal e vertical de conteúdos implantados no 2º semestre de 2009 no Curso de Graduação em Administração em uma Universidade Pública Estadual da Região Sul do Brasil. Os conceitos e as características dos paradigmas tradicional e emergente da ciência e seus reflexos na educação são discutidos, além de a questão da interdisciplinaridade, com suas respectivas modalidades e classificações, ser observada no referencial teórico. A pesquisa é exploratória, descritiva e interpretativa. Os dados e as informações foram coletados por meio de pesquisa bibliográfica, observação participante e análise documental. Eles foram organizados e sistematizados a partir dos indicativos constantes nos planos de ensino (objetivos das disciplinas, conteúdos programáticos, metodologias de ensino-aprendizagem, sistemas de avaliação e referências bibliográficas). Os dados e as informações foram descritos e interpretados a partir da vivência dos autores no curso de Administração, complementada pelos fundamentos teóricos e práticos discutidos pelos estudiosos da área. O programa foi operacionalizado por meio de integração sistêmica e complementar quando da realização de reuniões de sensibilização, de reuniões pedagógicas e de reuniões de socialização, além de sessões de feedback. O programa revelou que: a) gestores, docentes e alunos precisam estar identificados e comprometidos para entender e perceber as consequências do paradigma cartesiano, assim como a relevância dos fundamentos do paradigma da complexidade, na implantação de programas voltados à interdisciplinaridade; b) a interdisciplinaridade identifica e nomeia uma mediação possível entre saberes e competências, garantindo a convivência criativa com as diferenças, como percebido na identificação de temas e conceitos em comum; e c) a prática interdisciplinar representa uma possibilidade pedagógica para instigar, indagar e intervir, como verificado nas reuniões pedagógicas, suscitando o que Freire (2005) chamou de "curiosidade epistemológica".

The general aim of this paper is to discuss the bases, operationalization methodology, and results of the program for horizontal and vertical integration of syllabi implemented in the 2nd semester of 2009 in the undergraduate Management course from a State Public University at Southern Brazil. The concepts and characteristics of the traditional and emergent paradigms of science and their impacts on education are discussed, besides, the issue of interdisciplinarity, and its respective modalities and classifications, is considered in the theoretical framework. The research is exploratory, descriptive, and interpretive. Data and information were collected through bibliographical survey, participative observation, and documental analysis. They were organized and systematized according to indicatives from teaching plannings (disciplines goals, syllabi, teaching-learning methodologies, evaluation systems, and bibliographical references). Data and information were described and interpreted according to the authors' experience in the Management undergraduate course, supplemented by the theoretical and practical grounding discussed by scholars from this field. The program was operationalized through systemic and complementary integration during sensitization meetings, pedagogical meetings, and socialization meetings, as well as feedback sessions. The program revealed that: a) managers, professors, and students must be focused and committed to understand and realize the consequences of the Cartesian paradigm, as well as the relevance of the complexity paradigm foundations, in the implementation of programs concerning interdisciplinarity; b) interdisciplinarity identifies and designates a possible mediation between knowledge and skills, ensuring a creative interaction with differences, as noticed in the identification of shared themes and concepts; and c) the interdisciplinary practice represents a pedagogical possibility to instigate, investigate, and intervene, as observed during pedagogical meetings, evoking what Freire (2005) named "epistemological curiosity".

7687 downloads Cited 1 time in SciELO

13.

II Diretriz de Avaliação Perioperatória da Sociedade Brasileira de Cardiologia
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Feitosa, Alina Coutinho Rodrigues

; Marques, André Coelho

; Caramelli, Bruno

; Ayub, Beatriz

; Polanczyk, Carisi A.

; Jardim, Carlos

; Vieira, Carolina L. Zilli

; Pinho, Claudio

; Calderaro, Daniela

; Gualandro, Danielle Menosi

; Iezzi, Denise

; Ikeoka, Dimas T.

; Schreen, Dirk

; D'Amico, Elbio Antonio

; Pfeferman, Elcio

; Lima, Emerson Quintino de

; Burdmann, Emmanuel de A.

; Pachon, Enrique

; Machado, Fabio Santana

; Galas, Filomena Regina Barbosa Gomes

; Paula, Flávio Jota de

; Carvalho, Francine Corrêa de

; Feitosa-Filho, Gilson Soares

; Prado, Gustavo Faibischew

; Lopes, Heno F.

; Lima, José Jaime Galvão de

; Marchini, Julio Flavio Meirelles

; Fornari, Luciana S.

; Drager, Luciano F.

; Vacanti, Luciano Janussi

; Hajjar, Ludhmila Abrahão

; Rohde, Luis Eduardo P.

; Gowdak, Luís Henrique

; Cardoso, Luiz Francisco

; Vieira, Marcelo Luiz Campos

; Monachini, Maristela C.

; Macatrão, Milena

; Yu, Pai Ching

; Villaça, Paula Ribeiro

; Farsky, Pedro Silvio

; Lopes, Renato Delascio

; Bagnatori, Renato Scotti

; Heinisch, Roberto Henrique

; Gualandro, Sandra F. Menosi

; Accorsi, Tarso Augusto Duenhas

; Ávila, Walkiria Samuel

; Mathias Jr., Wilson

Arquivos Brasileiros de Cardiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2011, Volume 96 N. 3 Pages 1 - 68

Abstract: Pt | Text: Pt | PDF: Pt

53329 downloads

14.

CT evaluation of apical canal transportation associated with stainless steel hand files, oscillatory technique and ProTaper rotary system
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Hartmann, Mateus Silveira Martins

; Fontanella, Vânia Regina Camargo

; Vanni, José Roberto

; Fornari, Volmir João

; Barletta, Fernando Branco

Brazilian Dental Journal

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2011, Volume 22 N. 4 Pages 288 - 293

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este estudo utilizou a tomografia computadorizada (TC) para comparar o transporte do canal radicular nos canais mésio-vestibulares de molares superiores preparados por diferentes técnicas. Sessenta molares superiores foram divididos em 3 grupos (n=20) de acordo com a técnica utilizada para o preparo do canal radicular: instrumentação manual com limas K-Flexofile, limas K-Flexofile acopladas a um sistema oscilatório e sistema rotatório ProTaper. Imagens de TC pré e pós-instrumentação foram obtidas 3 mm aquém do forame apical e superpostas para comparar o transporte do canal. Os dados foram analisados estatisticamente pela Análise de Variância (ANOVA) e Teste de Tukey utilizando o software SPSS (α=0,05). Na direção vestibular, a técnica manual produziu significantemente menos transporte do canal radicular do que a técnica oscilatória (p<0,05) e ambas foram similares a técnica rotatória (p>0,05). Nas direções distal e disto-palatina, a técnica oscilatória produziu mais transporte do canal radicular (p<0,05). Na direção mésio-palatina, a técnica oscilatória produziu mais transporte do canal radicular do que a técnica manual (p<0,05), sendo que ambas foram similares à técnica rotatória (p>0,05). Em conclusão, todas as técnicas produziram transporte do canal radicular e a técnica oscilatória produziu os maiores desgastes de dentina na direção interna da curvatura.

This study used computed tomography (CT) to compare apical canal transportation in mesiobuccal canals of maxillary molars prepared with different techniques. Sixty teeth were assigned to 3 groups (n=20), according to the technique used for root canal instrumentation: hand instrumentation with K-Flexofiles, K-Flexofiles activated by an oscillatory system and ProTaper NiTi rotary system. Pre and post-instrumentation CT images were obtained 3 mm short of the apical foramen and were superimposed to compare canal transportation. Data were analyzed statistically by ANOVA and Tukey's test using the SPSS software (α=0.05). In the buccal direction, the manual technique produced significantly less canal transportation than the oscillatory technique (p<0.05) and both were similar to the rotary technique (p>0.05). In the distal and distopalatal directions, the oscillatory technique produced more canal transportation (p<0.05). In the mesiopalatal direction, the oscillatory technique produced more canal transportation than the manual technique (p<0.05), and both were similar to the rotary technique (p>0.05). In conclusion, all techniques produced canal transportation, and the oscillatory technique produced the greatest removal of root dentin toward the innerside of the root curvature.

5123 downloads

15.

Soundscape design through evolutionary engines
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Fornari, José

; Maia Jr., Adolfo

; Manzolli, Jônatas

Journal of the Brazilian Computer Society

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2008, Volume 14 N. 3 Pages 51 - 64

Abstract: En | Text: En | PDF: En

Two implementations of an Evolutionary Sound Synthesis method using the Interaural Time Difference (ITD) and psychoacoustic descriptors are presented here as a way to develop criteria for fitness evaluation. We also explore a relationship between adaptive sound evolution and three soundscape characteristics: key-sounds, key-signals and sound-marks. Sonic Localization Field is defined using a sound attenuation factor and ITD azimuth angle, respectively (Ii, Li). These pairs are used to build Spatial Sound Genotypes (SSG) and they are extracted from a waveform population set. An explanation on how our model was initially written in MATLAB is followed by a recent Pure Data (Pd) implementation. It also elucidates the development and use of: parametric scores, a triplet of psychoacoustic descriptors and the correspondent graphical user interface.

2315 downloads

Showing

itens per page

Page of 2 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »