Results: 17
#1
au:LIMA FILHO, O. F. DE
Filters
Order by
Page
of 2
Next
1.
Effect of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide in combination with antibacterial drugs against Klebsiella pneumoniae
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
CORDEIRO, LAÍSA V.
; SOUZA, HELIVALDO D.S.
; SOUSA, ALESON P.
; ANDRADE JÚNIOR, FRANCISCO P. DE
; FIGUEIREDO, PEDRO T.R. DE
; OLIVEIRA, RAFAEL F. DE
; ATHAYDE FILHO, PETRÔNIO F. DE
; OLIVEIRA-FILHO, ABRAHÃO A.
; LIMA, EDELTRUDES DE O.
.
Abstract Klebsiella pneumoniae is a species of Gram-negative bacteria related to a wide range of infections and high rates of drug resistance. The combined use of antibacterial agents is one of the strategies that has been analyzed in recent years as part of the alternatives in the treatment of drug-resistant infections. Recently, the antibacterial activity of of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide has been demonstrated against K. pneumoniae, also indicating that this acetamide did not show significant cytotoxic potential in preliminary tests. Thus, it becomes an interesting substance for future studies that explore its antimicrobial capacity, including investigating its association with antibacterial drugs. Based on this, this research aimed to analyze the effects of the association of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide (CFA) with ciprofloxacin, cefepime, ceftazidime, meropenem and imipenem against K. pneumoniae strains. The results showed additivity when the substance was combined with ciprofloxacin and cefepime, indifference when associated with ceftazidime and synergistic effect when combined with meropenem and imipenem. Thus, the acetamide was able to optimize the effects of antibacterial drugs, reducing the concentrations necessary to cause bacterial death. These data indicate a potential future clinical use of these combinations, and further studies are needed to analyze this viability.
2.
Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Fink, Thais T.
; Marques, Heloisa H.S.
; Gualano, Bruno
; Lindoso, Livia
; Bain, Vera
; Astley, Camilla
; Martins, Fernanda
; Matheus, Denise
; Matsuo, Olivia M.
; Suguita, Priscila
; Trindade, Vitor
; Paula, Camila S.Y.
; Farhat, Sylvia C.L.
; Palmeira, Patricia
; Leal, Gabriela N.
; Suzuki, Lisa
; Odone Filho, Vicente
; Carneiro-Sampaio, Magda
; Duarte, Alberto José S.
; Antonangelo, Leila
; Batisttella, Linamara R.
; Polanczyk, Guilherme V.
; Pereira, Rosa Maria R.
; Carvalho, Carlos Roberto R.
; Buchpiguel, Carlos A.
; Latronico, Ana Claudia
; Seelaender, Marilia
; Silva, Clovis Artur
; Pereira, Maria Fernanda B.
; Sallum, Adriana M. E.
; Brentani, Alexandra V. M.
; Neto, Álvaro José S.
; Ihara, Amanda
; Santos, Andrea R.
; Canton, Ana Pinheiro M.
; Watanabe, Andreia
; Santos, Angélica C. dos
; Pastorino, Antonio C.
; Franco, Bernadette D. G. M.
; Caruzo, Bruna
; Ceneviva, Carina
; Martins, Carolina C. M. F.
; Prado, Danilo
; Abellan, Deipara M.
; Benatti, Fabiana B.
; Smaria, Fabiana
; Gonçalves, Fernanda T.
; Penteado, Fernando D.
; Castro, Gabriela S. F. de
; Gonçalves, Guilherme S.
; Roschel, Hamilton
; Disi, Ilana R.
; Marques, Isabela G.
; Castro, Inar A.
; Buscatti, Izabel M.
; Faiad, Jaline Z.
; Fiamoncini, Jarlei
; Rodrigues, Joaquim C.
; Carneiro, Jorge D. A.
; Paz, Jose A.
; Ferreira, Juliana C.
; Ferreira, Juliana C. O.
; Silva, Katia R.
; Bastos, Karina L. M.
; Kozu, Katia
; Cristofani, Lilian M.
; Souza, Lucas V. B.
; Campos, Lucia M. A.
; Silva Filho, Luiz Vicente R. F.
; Sapienza, Marcelo T.
; Lima, Marcos S.
; Garanito, Marlene P.
; Santos, Márcia F. A.
; Dorna, Mayra B.
; Aikawa, Nadia E.
; Litvinov, Nadia
; Sakita, Neusa K.
; Gaiolla, Paula V. V.
; Pasqualucci, Paula
; Toma, Ricardo K.
; Correa-Silva, Simone
; Sieczkowska, Sofia M.
; Imamura, Marta
; Forsait, Silvana
; Santos, Vera A.
; Zheng, Yingying
.
OBJECTIVES: To prospectively evaluate demographic, anthropometric and health-related quality of life (HRQoL) in pediatric patients with laboratory-confirmed coronavirus disease 2019 (COVID-19) METHODS: This was a longitudinal observational study of surviving pediatric post-COVID-19 patients (n=53) and pediatric subjects without laboratory-confirmed COVID-19 included as controls (n=52) was performed. RESULTS: The median duration between COVID-19 diagnosis (n=53) and follow-up was 4.4 months (0.8-10.7). Twenty-three of 53 (43%) patients reported at least one persistent symptom at the longitudinal follow-up visit and 12/53 (23%) had long COVID-19, with at least one symptom lasting for >12 weeks. The most frequently reported symptoms at the longitudinal follow-up visit were headache (19%), severe recurrent headache (9%), tiredness (9%), dyspnea (8%), and concentration difficulty (4%). At the longitudinal follow-up visit, the frequencies of anemia (11% versus 0%, p=0.030), lymphopenia (42% versus 18%, p=0.020), C-reactive protein level of >30 mg/L (35% versus 0%, p=0.0001), and D-dimer level of >1000 ng/mL (43% versus 6%, p=0.0004) significantly reduced compared with baseline values. Chest X-ray abnormalities (11% versus 2%, p=0.178) and cardiac alterations on echocardiogram (33% versus 22%, p=0.462) were similar at both visits. Comparison of characteristic data between patients with COVID-19 at the longitudinal follow-up visit and controls showed similar age (p=0.962), proportion of male sex (p=0.907), ethnicity (p=0.566), family minimum monthly wage (p=0.664), body mass index (p=0.601), and pediatric pre-existing chronic conditions (p=1.000). The Pediatric Quality of Live Inventory 4.0 scores, median physical score (69 [0-100] versus 81 [34-100], p=0.012), and school score (60 [15-100] versus 70 [15-95], p=0.028) were significantly lower in pediatric patients with COVID-19 at the longitudinal follow-up visit than in controls. CONCLUSIONS: Pediatric patients with COVID-19 showed a longitudinal impact on HRQoL parameters, particularly in physical/school domains, reinforcing the need for a prospective multidisciplinary approach for these patients. These data highlight the importance of closer monitoring of children and adolescents by the clinical team after COVID-19.
3.
Concentration of Metals in Plant Litter Produced in Regions of Caatinga in Southwest Bahia, Brazil
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Lima, Joaly S. S. O.
; Gomes, Ivaldo S.
; Cerqueira, Uillian M. F. M.
; Carneiro, Paulo L. S.
; Sousa Filho, Hélio R.
; Jesus, Raildo M. de
; Bezerra, Marcos A.
.
Journal of the Brazilian Chemical Society
- Journal Metrics
Plant litter has several functions in a forest ecosystem. Studies about plant litter are of great importance to better understand and conserve ecological environments. The objective of this study was to investigate the concentration of metals (Fe, Co, Ca, Cu, Ni, Mg, Mn and Zn) in Caatinga plant litter in the southwest region of Bahia. Plant litter was collected in summer (January/2017) and winter (August/2017). Concentrations were determined by flame atomic absorption spectrometry (FAAS). The results were submitted to multivariate analysis, principal component analysis (PCA), and hierarchical cluster analysis (HCA). The average amount of plant litter found in January and August was 1190 and 1329 kg ha-1, respectively. The twigs fraction provided the largest amount of biomass to the plant litter since this deposition occurred in greater quantity in August, a period of drought. Metal concentrations (g kg-1) in the analyzed samples ranged from 1.39-257 (Fe), < limit of quantification (LOQ)-0.269 (Co), 0.0036-0.61 (Cu), 1.39-8.76 (Ca), 0.0022-0.56 (Ni), 0.137-1.52 (Mg), 0.033-1.91 (Mn) and 0.0022-0.8 (Zn). The multivariate analysis showed that the composition of plant litter is altered seasonally.
https://doi.org/10.21577/0103-5053.20200029
206 downloads
4.
GC-MS-Based Metabolomic Profiles Combined with Chemometric Tools and Cytotoxic Activities of Non-Polar Leaf Extracts of Spondias mombin L. and Spondias tuberosa Arr. Cam.
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Guedes, Jhonyson A. C.
; Alves Filho, Elenilson G.
; Silva, Maria F. S.
; Rodrigues, Tigressa H. S.
; Ramires, Christiane M. C.
; Lima, Maria A. C.
; Silva, Gisele S.
; Pessoa, Cláudia Ó.
; Canuto, Kirley M.
; Brito, Edy S.
; Alves, Ricardo E.
; Nascimento, Ronaldo F.
; Zocolo, Guilherme J.
.
Agroindustrial residues, such as leaves of fruit plants, can be sources of bioactive molecules, thus adding value to co-products that are rarely explored in agroindustry. In this context, this study aimed to look into the phytochemical profiles in detail and to explore the antitumor potential of S. tuberosa and S. mombin leaves. We observed that, S. tuberosa leaf extract was cytotoxic in both tumor and healthy cells. S. mombin extracts selectively inhibited cell proliferation in the tumor cell line for prostate cancer (PC3) and did not significantly affect healthy cells. The metabolic profiles of the extracts were evaluated by gas chromatography coupled with mass spectrometry and twenty-three metabolites were identified. The correlation of metabolic profiles with cytotoxic tests indicated possible chemical markers that may be responsible for the inhibition of cell proliferation. This study revealed that the unexplored co-products in agroindustry may have great therapeutic potential, and therefore should be screened for biologically active compounds.
https://doi.org/10.21577/0103-5053.20190185
596 downloads
5.
Landfill leachate as nutritional source in castor bean cultivation under semi-arid conditions
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Andrade Filho, Jerônimo
; Dias, Nildo da S.
; Batista, Rafael O.
; Santos Júnior, José A.
; Santos, Anne G. D.
; Lima, Ana L. F.
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO A pertinência do uso da tecnologia para destinação racional dos resíduos oriundos das mais diversas atividades humanas é iminentemente precípua. Neste contexto, entre setembro de 2014 e janeiro de 2015, em Mossoró, RN (5º 11' 31" Sul - 37º 20' 40" Oeste), desenvolveu-se o presente trabalho com o objetivo de avaliar o uso de estratégias com vistas ao aproveitamento do percolado de aterro sanitário como fonte de água e nutrientes na agricultura. Para tal, submeteram-se plantas de mamona (Ricinus communis L.) cv. BRS Energia, cultivadas em Argissolo vermelho-amarelo Eutrófico, a estratégias de aplicação da lâmina de irrigação, a saber, a aplicação inicial do percolado de aterro sanitário correspondente a 20, 40, 60 e 80% da lâmina e a posterior aplicação do percentual restante da lâmina de irrigação em água de abastecimento, mais uma testemunha que consistiu na irrigação com água de abastecimento + adubação mineral recomendada para a cultura. Estes tratamentos foram alocados em blocos ao acaso, com quatro repetições, totalizando vinte parcelas experimentais. Verificou-se que a fertilização mineral resultou em respostas biométricas mais expressivas no início do ciclo, no entanto, ao final, os tratamentos à base de percolado proporcionaram resultados, inclusive de produção, compatíveis com a testemunha, com destaque para as plantas irrigadas com 20% da lâmina.
ABSTRACT The relevance of using technology for the rational destination of waste from a wide range of human activities is imminently paramount. In this context, between September 2014 and January 2015, in Mossoró, RN, Brazil (5º 11' 31" S; 37º 20' 40" W), the present work was conducted to evaluate strategies for the utilization of landfill leachate as source of water and nutrients in agriculture. For this, castor bean plants (Ricinus communis L.), cv. BRS Energia, cultivated in eutrophic Red Yellow Argisol, were subjected to irrigation depth application strategies, namely: initial application of leachate corresponding to 20, 40, 60 and 80% of the irrigation depth and subsequent application of the remaining water depth percentage using public-supply water, plus one control, which consisted of irrigation with public-supply water + mineral fertilization recommended for the crop. These treatments were set in randomized blocks, with four replicates, totalizing twenty experimental plots. Mineral fertilization resulted in more expressive biometric responses at the beginning of the cycle; however, at the end, treatments based on leachate led to results, including of production, compatible with the control, especially plants irrigated with the 20% irrigation depth.
https://doi.org/10.1590/1807-1929/agriambi.v22n6p378-382
583 downloads
6.
Zornioside, a dihydrochalcone C-glycoside, and other compounds from Zornia brasiliensis
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Nascimento, Yuri M.
; Abreu, Lucas S.
; Lima, Ramon L.
; Silva, Anne Dayse S.
; Costa, Vicente Carlos O.
; Melo, José Iranildo M.
; Scotti, Marcus Tulius
; Sobral, Marianna V.
; Araujo, Silvany S.
; G. Filho, Manoel Adrião
; Silva, Marcelo S.
; Tavares, Josean F.
.
ABSTRACT The secondary metabolites of the aerial parts of Zornia brasiliensis Vogel, Fabaceae, and the biological activity of one of these secondary metabolites were characterized in this study. A phytochemical investigation was performed using chromatographic techniques including analytical and preparative reverse-phase HPLC column sequences, which resulted in the isolation of fourteen compounds: one previously undescribed C-glycosylated dihydrochalcone (zornioside), one cyclitol (D-pinitol), one glycosylated megastigmane (roseoside) and eleven phenolic compounds: 7-methoxyflavanone, 7,4'-dimethoxyisoflavone, medicarpin, 2'-4'-dihydroxychalcone, onionin, isoorientin-3'-O-methyl ether, isovitexin, glycosylated (Z)-O-coumaric acid, glycosylated (E)-O-coumaric acid, dihydromelilotoside, and isoorientin. The structures of the isolated compounds were determined based on 1D and 2D-NMR, HRESIMS, IR and CD spectroscopic analyses. The cytotoxic activity of zornoside was assessed against tumor cell lines (MCF-7, HCC1954, T-47D, 4T1, HL60), and a non-tumor cell line (RAW264.7) using MTT assay. The compound zornioside was selectively cytotoxic for HL60 leukemia cells (IC50: 37.26 µM).
https://doi.org/10.1016/j.bjp.2018.02.003
621 downloads
7.
Helminth parasites of Phyllodactylidae and Gekkonidae lizards in a Caatinga ecological station, northeastern Brazil
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Lima, Vandeberg F.
; Brito, Samuel V.
; Araujo Filho, João A.
; Teles, Diêgo A.
; Ribeiro, Samuel C.
; Teixeira, Adonias A. M.
; Pereira, Antonio M. A.
; Almeida, Waltécio O.
.
Resumo Nós investigamos os parasitas de cinco espécies de lagartos pertencentes às famílias Phyllodactylidae (Phyllopezus pollicaris e Gymnodactylus geckoides) e Gekkonidae (Hemidactylus agrius, Lygodactylus klugei e Hemidactylus brasilianus) em região semiárida do Brasil. Seis espécies de nematoides foram encontrados: Parapharyngodon alvarengai e Spauligodon oxkutzcabiensis (Pharyngodonidae), Physaloptera lutzi (Physalopteridae), Skrjabinelazia intermedia (Seuratidae), Trichospirura sp. (Rhabdochonidae), Piratuba sp. (Onchocercidae) e uma espécie de cestódeo, Oochoristica sp. (Linstowiidae). As espécies de maiores prevalências foram S. oxkutzcabiensis, a qual infectou P. pollicaris (75%) e P. alvarengai a qual infectou G. geckoides (29.%). Nós documentamos novo registro de hospedeiro para lagartos na América do Sul pertencente ao gênero Trichospirura, o qual é comum em mamíferos, e 16 novas ocorrências de espécies parasitas nas cinco espécies de lagartos aqui estudadas.
Abstract We investigated the parasites of five lizard species belonging to Phyllodactylidae (Phyllopezus pollicaris and Gymnodactylus geckoides) and Gekkonidae (Hemidactylus agrius, Lygodactylus klugei and Hemidactylus brasilianus) families in a semiarid region of Brazil. Six nematode species were identified: Parapharyngodon alvarengai and Spauligodon oxkutzcabiensis (Pharyngodonidae), Physaloptera lutzi (Physalopteridae), Skrjabinelazia intermedia (Seuratidae), Trichospirura sp. (Rhabdochonidae) and Piratuba sp. (Onchocercidae), and a cestode species, Oochoristica sp. (Linstowiidae). The most prevalent species were Spauligodon oxkutzcabiensis, which infected P. pollicaris (75%), and Parapharyngodon alvarengai, which infected G. geckoides (29%). South American lizards were identified as being new hosts for the Trichospirura genus (a usual parasite of mammals), and there were 16 new occurrences of parasite species in the five lizard species studied herein.
https://doi.org/10.1590/1676-0611-bn-2016-0263
2000 downloads
8.
Update of the Brazilian floristic list of Algae and Cyanobacteria
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Menezes, Mariângela
; Bicudo, Carlos E. M.
; Moura, Carlos W. N.
; Alves, Aigara M.
; Santos, Alana A.
; Pedrini, Alexandre de G.
; Araújo, Andréa
; Tucci, Andrea
; Fajar, Aurelio
; Malone, Camila
; Kano, Cecília H.
; Sant'Anna, Célia L.
; Branco, Ciro Z.
; Odebrecht, Clarisse
; Peres, Cleto K.
; Neuhaus, Emanuel B.
; Eskinazi-Leça, Enide
; Aquino, Eveline
; Nauer, Fabio
; Santos, Gabriel N.
; Amado Filho, Gilberto M.
; Lyra, Goia M.
; Borges, Gyslaine C.P.
; Costa, Iara O.
; Nogueira, Ina de S.
; Oliveira, Ivania B.
; Paula, Joel. C.de
; Nunes, José M. de C.
; Lima, Jucicleide C.
; Santos, Kleber R.S.
; Ferreira, Leandro C.
; Gestinari, Lísia M.S.
; Cardoso, Luciana S.
; Figueiredo, Marcia A.O.
; Silva, Marcos H.
; Barreto, Maria B.B.B.
; Henriques, Maria C.O.
; Cunha, Maria da G.G.S.
; Bandeira-Pedrosa, Maria E.
; Oliveira-Carvalho, Maria F.
; Széchy, Maria T.M.
; Azevedo, Maria T.P.
; Oliveira, Mariana C. de
; Cabezudo, Mariê M.
; Santiago, Marilene F.
; Bergesh, Marli
; Fujii, Mutuê T.
; Bueno, Norma C.
; Necchi Jr., Orlando
; Jesus, Priscila B.
; Bahia, Ricardo G.
; Khader, Samir
; Alves-da-Silva, Sandra M.
; Guimarães, Silvia M.P.B.
; Pereira, Sonia M.B.
; Caires, Taiara A.
; Meurer, Thamis
; Cassano, Valéria
; Werner, Vera R.
; Gama Jr., Watson A. da
; Silva, Weliton J. da
.
Resumo Apresenta-se uma síntese atualizada de informações sobre algas no Brasil objetivando refinar os dados reunidos até o presente, bem como avaliar os avanços sobre o conhecimento da diversidade de algas no país desde a publicação do Catálogo de Plantas e Fungos do Brasil. Os resultados de 2015 mostraram um acréscimo de 1.250 espécies (35.7%) a um total de 4.747 em relação a 2010. As classes mais diversas em número de espécies foram Bacillariophyceae, Conjugatophyceae, Florideophyceae, Cyanophyceae, Dinophyceae e Euglenophyceae. Bacillariophyceae e Cyanophyceae tiveram o maior acréscimo de espécies no intervalo de cinco anos. A região Sudeste e Sul foram as mais diversas, porém, as regiões Nordeste com os estados do Piauí e Sergipe e Centro-Oeste com os estados de Mato Grosso, Goiás e Distrito Federal destacaram-se no cenário da biodiversidade nacional. Apesar da escassez de taxonomistas e da infraestrutura limitada, os resultados obtidos evidenciaram um avanço significativo no conhecimento da diversidade de algas no país nesse período de cinco anos, iniciando uma mudança quanto as diferenças geográficas regionais.
Abstract An updated synthesis of cyanobacteria and algae information is presented for Brazil aiming to refine the data gathered to date and evaluate the progress of the biodiversity knowledge about these organisms in the country since the publication of the Catálogo de Plantas e Fungos do Brasil. The results of 2015 showed an increase of 1,250 species (35.7%) when compared to 2010, reaching a total of 4,747 species. The most diverse classes in species number were the Bacillariophyceae, Conjugatophyceae, Florideophyceae, Cyanophyceae, Dinophyceae and Euglenophyceae. Bacillariophyceae and Cyanophyceae had the highest increase in species number in the five-year interval. The Southeast and South regions were the most diverse, however, the Northeast, with the states of Piauí and Sergipe, and the Central-west region, with Mato Grosso, Goiás and Distrito Federal, also stood out in the national algal biodiversity scenario. Despite the shortage of taxonomists and limited infrastructure, the results showed a significant improvement in the knowledge regarding the diversity of cyanobacteria and algae in the country during the study period, starting to even out regional geographical differences caused by subsampling.
https://doi.org/10.1590/2175-7860201566408
4865 downloads
9.
Growing knowledge: an overview of Seed Plant diversity in Brazil
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
; Martins da Silva, Regina C.V.
; Martins, Ângela B.
; Martins, Erika R.
; Martins, Márcio L.L.
; Martins, Milena V.
; Martins, Renata C.
; Matias, Ligia Q.
; Maya-L., Carlos A.
; Mayo, Simon
; Mazine, Fiorella
; Medeiros, Debora
; Medeiros, Erika S.
; Medeiros, Herison
; Medeiros, João D.
; Meireles, José E.
; Mello-Silva, Renato
; Melo, Aline
; Melo, André L.
; Melo, Efigênia
; Melo, José I.M.
; Menezes, Cristine G.
; Menini Neto, Luiz
; Mentz, Lilian A.
; Mezzonato, A.C.
; Michelangeli, Fabián A.
; Milward-de-Azevedo, Michaele A.
; Miotto, Silvia T.S.
; Miranda, Vitor F.O.
; Mondin, Cláudio A.
; Monge, Marcelo
; Monteiro, Daniele
; Monteiro, Raquel F.
; Moraes, Marta D.
; Moraes, Pedro L.R.
; Mori, Scott A.
; Mota, Aline C.
; Mota, Nara F.O.
; Moura, Tania M.
; Mulgura, Maria
; Nakajima, Jimi N.
; Nardy, Camila
; Nascimento Júnior, José E.
; Noblick, Larry
; Nunes, Teonildes S.
; O'Leary, Nataly
; Oliveira, Arline S.
; Oliveira, Caetano T.
; Oliveira, Juliana A.
; Oliveira, Luciana S.D.
; Oliveira, Maria L.A.A.
; Oliveira, Regina C.
; Oliveira, Renata S.
; Oliveira, Reyjane P.
; Paixão-Souza, Bruno
; Parra, Lara R.
; Pasini, Eduardo
; Pastore, José F.B.
; Pastore, Mayara
; Paula-Souza, Juliana
; Pederneiras, Leandro C.
; Peixoto, Ariane L.
; Pelissari, Gisela
; Pellegrini, Marco O.O.
; Pennington, Toby
; Perdiz, Ricardo O.
; Pereira, Anna C.M.
; Pereira, Maria S.
; Pereira, Rodrigo A.S.
; Pessoa, Clenia
; Pessoa, Edlley M.
; Pessoa, Maria C.R.
; Pinto, Luiz J.S.
; Pinto, Rafael B.
; Pontes, Tiago A.
; Prance, Ghillean T.
; Proença, Carolyn
; Profice, Sheila R.
; Pscheidt, Allan C.
; Queiroz, George A.
; Queiroz, Rubens T.
; Quinet, Alexandre
; Rainer, Heimo
; Ramos, Eliana
; Rando, Juliana G.
; Rapini, Alessandro
; Reginato, Marcelo
; Reis, Ilka P.
; Reis, Priscila A.
; Ribeiro, André R.O.
; Ribeiro, José E.L.S.
; Riina, Ricarda
; Ritter, Mara R.
; Rivadavia, Fernando
; Rocha, Antônio E.S.
; Rocha, Maria J.R.
; Rodrigues, Izabella M.C.
; Rodrigues, Karina F.
; Rodrigues, Rodrigo S.
; Rodrigues, Rodrigo S.
; Rodrigues, Vinícius T.
; Rodrigues, William
; Romaniuc Neto, Sérgio
; Romão, Gerson O.
; Romero, Rosana
; Roque, Nádia
; Rosa, Patrícia
; Rossi, Lúcia
; Sá, Cyl F.C.
; Saavedra, Mariana M.
; Saka, Mariana
; Sakuragui, Cássia M.
; Salas, Roberto M.
; Sales, Margareth F.
; Salimena, Fatima R.G.
; Sampaio, Daniela
; Sancho, Gisela
; Sano, Paulo T.
; Santos, Alessandra
; Santos, Élide P.
; Santos, Juliana S.
; Santos, Marianna R.
; Santos-Gonçalves, Ana P.
; Santos-Silva, Fernanda
; São-Mateus, Wallace
; Saraiva, Deisy P.
; Saridakis, Dennis P.
; Sartori, Ângela L.B.
; Scalon, Viviane R.
; Schneider, Ângelo
; Sebastiani, Renata
; Secco, Ricardo S.
; Senna, Luisa
; Senna-Valle, Luci
; Shirasuna, Regina T.
; Silva Filho, Pedro J.S.
; Silva, Anádria S.
; Silva, Christian
; Silva, Genilson A.R.
; Silva, Gisele O.
; Silva, Márcia C.R.
; Silva, Marcos J.
; Silva, Marcos J.
; Silva, Otávio L.M.
; Silva, Rafaela A.P.
; Silva, Saura R.
; Silva, Tania R.S.
; Silva-Gonçalves, Kelly C.
; Silva-Luz, Cíntia L.
; Simão-Bianchini, Rosângela
; Simões, André O.
; Simpson, Beryl
; Siniscalchi, Carolina M.
; Siqueira Filho, José A.
; Siqueira, Carlos E.
; Siqueira, Josafá C.
; Smith, Nathan P.
; Snak, Cristiane
; Soares Neto, Raimundo L.
; Soares, Kelen P.
; Soares, Marcos V.B.
; Soares, Maria L.
; Soares, Polyana N.
; Sobral, Marcos
; Sodré, Rodolfo C.
; Somner, Genise V.
; Sothers, Cynthia A.
; Sousa, Danilo J.L.
; Souza, Elnatan B.
; Souza, Élvia R.
; Souza, Marcelo
; Souza, Maria L.D.R.
; Souza-Buturi, Fátima O.
; Spina, Andréa P.
; Stapf, María N.S.
; Stefano, Marina V.
; Stehmann, João R.
; Steinmann, Victor
; Takeuchi, Cátia
; Taylor, Charlotte M.
; Taylor, Nigel P.
; Teles, Aristônio M.
; Temponi, Lívia G.
; Terra-Araujo, Mário H.
; Thode, Veronica
; Thomas, W.Wayt
; Tissot-Squalli, Mara L.
; Torke, Benjamin M.
; Torres, Roseli B.
; Tozzi, Ana M.G.A.
; Trad, Rafaela J.
; Trevisan, Rafael
; Trovó, Marcelo
; Valls, José F.M.
; Vaz, Angela M.S.F.
; Versieux, Leonardo
; Viana, Pedro L.
; Vianna Filho, Marcelo D.M.
; Vieira, Ana O.S.
; Vieira, Diego D.
; Vignoli-Silva, Márcia
; Vilar, Thaisa
; Vinhos, Franklin
; Wallnöfer, Bruno
; Wanderley, Maria G.L.
; Wasshausen, Dieter
; Watanabe, Maurício T.C.
; Weigend, Maximilian
; Welker, Cassiano A.D.
; Woodgyer, Elizabeth
; Xifreda, Cecilia C.
; Yamamoto, Kikyo
; Zanin, Ana
; Zenni, Rafael D.
; Zickel, Carmem S
.
Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
33340 downloads
10.
Concurrent validity of the pressure biofeedback unit and surface electromyography in measuring transversus abdominis muscle activity in patients with chronic nonspecific low back pain
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Lima, Pedro O. P.
; Oliveira, Rodrigo R.
; Moura Filho, Alberto G.
; Raposo, Maria C. F.
; Costa, Leonardo O. P.
; Laurentino, Glória E. C.
.
CONTEXTUALIZAÇÃO: A Unidade de Biofeedback Pressórico (UBP) é uma ferramenta de avaliação usada na prática clínica e pesquisa científica para analisar indiretamente a atividade muscular do transverso abdominal (TrA). A validade concorrente da UBP em uma amostra clinicamente relevante ainda não está esclarecida. OBJETIVO: Avaliar a validade concorrente e acurácia diagnóstica da UBP em mensurar a atividade muscular do TrA em pacientes com dor lombar crônica inespecífica. MÉTODO: Este estudo foi realizado usando um delineamento de validação. Cinquenta pacientes com dor lombar crônica inespecífica foram recrutados. Para testar a validade concorrente, ambas as medidas pressóricas (teste índice) e eletromiográficas superficiais (teste padrão de referência) foram comparadas e coletadas por um fisioterapeuta a partir de uma manobra de contração voluntária do músculo TrA. RESULTADOS: Os participantes tinham em média 22 anos, 63,7 kg, 1,70 m de altura, e a duração média de dor lombar era de 1,9 ano. Observou-se um coeficiente Phi fraco e não significativo (r=0,2; p<0,20). Com relação aos testes de acurácia diagnóstica, os resultados sugerem uma baixa sensibilidade (60%) e especificidade (60%) da UBP. O valor preditivo positivo foi elevado (0,8), e o valor preditivo negativo foi baixo (0,2). Conclusões: A validade concorrente da UBP em mensurar a atividade muscular do TrA em pacientes com dor lombar crônica inespecífica é pobre, considerando a baixa correlação e acurácia diagnóstica com a EMG de superfície.
BACKGROUND: The Pressure biofeedback unit (PBU) is an assessment tool used in clinical practice and research aimed to indirectly analyze the transversus abdominis (TrA) muscle activity. The concurrent validity of the PBU in a clinically relevant sample is still unclear. OBJECTIVE: The purpose of this study was to evaluate the concurrent validity and diagnostic accuracy of the PBU in measuring TrA muscle activity in patients with chronic nonspecific low back pain. METHOD: This study was performed using a validation, cross-sectional design. Fifty patients with chronic nonspecific low back pain were recruited for this study. To test the concurrent validity both PBU measures (index test) and superficial electromyographic measures (reference-standard test) were compared and collected by a physical therapist in a series of voluntary contraction maneuvers of TrA muscle. RESULTS: Participants were on average 22 years old, weighed 63.7 kilos, 1.70 meters height and mean low back pain duration was 1.9 years. It was observed a weak and non-significant Phi coefficient (r=0.2, p<0.20). With regards to diagnostic accuracy tests, our results suggest a low sensitivity (60%) and specificity (60%) of the PBU. The positive predictive value was high (0.8) and negative predictive value was low (0.2). Conclusions: Concurrent validity of the PBU in measuring TrA muscle activity in patients with chronic nonspecific low back pain is poor given the low correlation and diagnostic accuracy with superficial EMG.
12252 downloads
11.
Correlation between electrochemical and theoretical studies on the leishmanicidal activity of twelve Morita-Baylis-Hillman adducts
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Paiva, Yen G. de
; Souza, Antônio A. de
; Lima-Junior, Claudio G.
; Silva, Fábio P. L.
; A. Filho, Edilson B.
; Vasconcelos, Camila C. de
; Abreu, Fabiane C. de
; Goulart, Marília O. F.
; Vasconcellos, Mário L. A. A.
.
O processo de biorredução enzimática do grupo nitro é de grande importância para a ação molecular de nitrocompostos aromáticos biologicamente ativos. Os métodos eletroquímicos são considerados ferramentas úteis para a simulação de processos metabólicos in vivo. No presente trabalho, realizaram-se estudos eletroquímicos em meio aprótico (N, N-dimetilformamida (DMF) mais perclorato de tetrabutilamônio (TBAP) 0,1 mol L-1) utilizando-se as técnicas de voltametria cíclica (CV), de pulso diferencial (DPV) e de onda quadrada (SWV) de 12 adutos de Morita-Baylis-Hillman (MBHA) com atividade leishmanicida significativa. Para facilitar a análise, os adutos foram agrupados em quatro classes de acordo com a cadeia lateral. Os estudos de CV evidenciam duas ondas referentes à redução do grupo nitro e uma ou duas outras ondas (em potencial mais negativo) relativas à redução da função carbonila α,β-insaturada ou da olefina ativada por grupos nitrila. Adutos orto-substituídos apresentam maior facilidade de redução quando comparados aos demais isômeros (meta e para) em função, provavelmente, da ligação de hidrogênio entre o grupo nitro e a hidroxila benzílica, o que estabiliza mais o produto eletrogerado do que o composto de partida. Derivados orto também mostram uma maior atividade leishmanicida em comparação com seus isômeros em cada série. Estudos conformacionais usando HF/6-31+G(d)/PCM como nível de cálculo evidenciaram este efeito. Valores calculados de dureza molecular (N) e de cargas atômicas (Q N) explicam corretamente os dados experimentais obtidos.
Enzymatic bioreduction of nitro groups plays an important role on the activity of biologically active nitroaromatic compounds. Electrochemical methods are useful tools to simulate in vivo metabolic processes. This work presents electrochemical studies in aprotic media (N, N-dimethylformamide (DMF) plus tetrabutylammonium perchlorate (TBAP) 0.1 mol L-1) using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and square wave voltammetry (SWV) of twelve Morita-Baylis-Hillman adducts (MBHA) with significant leishmanicidal activity. To facilitate the analysis, the molecules were grouped in four classes according to the side chain. CV studies show three up to four reduction waves, in which the first two waves are related to nitro group reduction. The other waves (presenting more negative potential) refer to the reduction of the α,β-unsaturated carbonyl or to the nitrile activated olefin side-chain. Ortho adducts present facilitated reduction in comparison to the other isomers (meta and para) possibly due to hydrogen bond formation between the benzylic-OH and the nitro group, which stabilizes the reduction product (anion radical nitro) more efficiently than the original compound. Ortho derivatives also present higher leishmanicidal activity upon comparison to the other derivatives of each class. Conformational studies using HF/6-31+G(d)/PCM as a calculation level highlight this effect. Molecular hardness (N) and atomic charges (Q N) values corroborate the obtained experimental data.
2694 downloads
12.
Mesoporous molecular sieve MCM-41 synthesis from fluoride media
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
A study of the synthesis of MCM-41 mesoporous molecular sieves in fluoride media, having no alkaline metal ions, was performed by changing the gel composition and crystallization temperature and time. X-ray diffraction and nitrogen adsorption analyses showed that highly ordered MCM-41 samples were obtained from gels with a NH4OH/SiO2 molar ratio in the 3.25-4.3 range (room temperature synthesis) or in the 4.3-20 range (24 hours at 373 K). During calcination, unit cell shrinkage, caused by high temperature polycondensation of the SiOH groups, was observed for all samples. The samples synthesized at high temperature (373 K) or using low pH gels (7.5) underwent lower unit cell shrinkage than those obtained at room temperature or high pH (9.0), indicating that the former samples had lower SiOH groups content than the latter. These highly-ordered samples showed large surface area (ca. 1100 m²/g) and pore volume (ca. 0.80 cm³/g), also presenting a narrow pore size distribution. Due to higher silicate polycondensation and a thicker pore wall, the samples synthesized at 373 K were more hydrothermally stable than those obtained at room temperature.
4612 downloads
13.
Evaluation of the antifungal activity and mode of action of Lafoensia pacari A. St.-Hil., Lythraceae, stem-bark extracts, fractions and ellagic acid
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Silva Junior, Iberê F.
; Raimondi, Marcela
; Zacchino, Susana
; Cechinel Filho, Valdir
; Noldin, Vânia F.
; Rao, Vietla S.
; Lima, Joaquim C. S.
; Martins, Domingos T. O.
.
Os extratos, frações e ácido elágico, isolados da entrecasca de Lafoensia pacari A. St.-Hil., Lythraceae, foram testados in vitro para atividade antifúngica, frente a um painel de leveduras, hialo-hifomicetos e dermatófitos, utilizando o método de microdiluição. O extrato EtOH, frações e ácido elágico exibiram atividade contra Candida spp. e Saccharomyces cerevisiae com valores de CIM entre 250-1000 µg/mL, porιm não mostraram ação contra fungos filamentosos e dermatófitos (CIM>1000 µg/mL). Os extratos ativos foram avaliados nos ensaios de inibição do crescimento das hifas de Neurospora crassa, no teste do sorbitol, e pelo estudo do efeito do ergosterol na CIM do ácido elágico. Os extratos ativos, frações e ácido elágico mostraram zonas manchadas ao redor dos discos de papel e induziram malformações nas hifas. Além disso, a CIM do ácido elágico contra Saccharomyces cerevisiae passou de 62 para 250 µg/mL na presença do sorbitol 0,8 M, sugerindo que o ácido elágico provavelmente poderia exercer ação na parede celular fúngica. Esses resultados indicam que o ácido elágico pode ser o principal composto antifúngico de Lafoensia pacari, sugerindo que o modo de ação antifúngico desses extratos e ácido elágico poderia estar associado à inibição da parede celular fúngica.
Stem-bark extracts, fractions and the isolated constituent, ellagic acid of Lafoensia pacari St. Hil. (Lythraceae) were in vitro assayed for antifungal activity against a panel of yeasts, hialohyphomycetes as well as dermatophytes with the microbroth dilution method. The EtOH extract and its fractions and ellagic acid exhibited activity against Candida spp and Saccharomyces cerevisiae with MIC values between 250-1000 µg/mL, but they showed no action against filamentous fungi and dermatophytes (MIC>1000 µg/mL). Active extracts were evaluated in Neurospora crassa hyphal growth inhibition and sorbitol assays and then the effect of ergosterol on the MIC of ellagic acid was studied. The active extracts and its fractions and ellagic acid showed a blotchy zone around the paper disk and induced malformations of the hypha. Besides, MIC of the ellagic acid against the Saccharomyces cerevisiae was raised from 62 to 250 µg/mL in the presence of sorbitol 0.8 M, suggesting that the ellagic acid would probably exert its action on fungal cell wall. These results indicate that ellagic acid might be the main active antifungal compound of Lafoensia pacari and further suggest that the mode of antifungal action of these extracts and ellagic acid could be associated with the inhibition of fungal cell wall.
5554 downloads
14.
Identificação de mudanças florestais por 13C e 15N dos solos da Chapada do Araripe, Ceará
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Mendonça, Luiz A. R.
; Frischkorn, Horst
; Santiago, Marlúcia F.
; Camargo, Plínio B. de
; Lima, José O. G. de
; Mendes Filho, Josué
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
A matéria orgânica (MO) encontrada no solo pode ser uma ferramenta auxiliar na identificação de uma vegetação remota. Na Floresta Nacional do Araripe e circunvizinhança, na Chapada do Araripe, realizou-se o presente estudo, em que as medidas de d13C e d15N da MO dos solos foram utilizadas para: (i) avaliar os valores atuais desses parâmetros; (ii) analisar a variabilidade natural do d13C no solo de diferentes formações florestais e (iii) indicar o declínio de florestas. Verificou-se que os solos das áreas hoje preservadas e cuja MO na superfície mostra d13C tipo C3, da vegetação atual, e uma mistura C3-C4 em profundidade, correspondem a ecossistemas antropizados no passado por uso agrícola; já os solos que mantiveram o d13C tipo C3 em todo o perfil se referem a ecossistemas antropizados, porém por uso não agrícola. Na caatinga, o perfil do d15N indicou um solo mais mineralizado e com menos MO. As áreas reflorestadas e preservadas apresentaram recuperação da MO.
The organic matter (OM) of soils can be used as an auxiliary tool for the identification of past vegetation. In the Floresta Nacional do Araripe and its surroundings, on top of the Araripe Plateau, a study was made using measurements of d13C and d15N of soil OM in order to (i) assess present day values for these parameters; (ii) to analyse natural variations of d13C in soils from different formations of forest; (iii) and to indicate forest decline. It was found that soils from (at present) protected areas, the OM of which exhibits C3 type d13C of the present vegetation in surface samples but of the C3-C4 type in depth, correspond to ecosystems anthropized in the past through agriculture. Soils maintaining d13C of the C3 type throughout the entire profile refer to ecosystems anthropized through non-agricultural exploitation. "Caatinga" samples exhibit a d15N profile that indicates a soil more mineralized and with less OM, whereas reforested preserved areas show recovery of OM.
3538 downloads
15.
Variabilidade interanual da profundidade óptica da atmosfera sobre Maceió, AL
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Lima, Edivania de A.
; Molion, Luis C. B.
; Gomes Filho, Manoel F.
; Firmino, Janne L. da N.
; Silva, Alcides O. da
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
A radiação solar de ondas curtas (ROC) que penetra na atmosfera, depende principalmente da turbidez atmosférica e da cobertura de nuvens. Realizou-se um estudo sobre a variabilidade da profundidade óptica da atmosfera sobre Maceió, AL, utilizando-se dados de radiação solar incidente no topo da atmosfera e emitida na superfície, de onda longa (ROL), cobertura de nuvens, água precipitável e precipitação, retirados do conjunto de dados de Reanálise do NCAR/NCEP. O ciclo anual da profundidade óptica estimada com esses dados foi comparado com os dados de radiação global medidos no Departamento de Meteorologia da UFAL (1997-1999). Nos meses de janeiro a junho de 1997, Maceió teve cerca de 60 a 80% de cobertura por nebulosidade e durante os meses de abril a julho, período chuvoso para Maceió, ocorreu maior cobertura de nuvens, cerca de 70 a 80% da cobertura do céu, aumentando a atenuação de ROC, sendo que as maiores concentrações de ROC foram verificadas no ano de 1999 (La Niña) com um máximo de 10 mm d-1 de precipitação. Os valores de transmissividade totalizadora calculados em função do espalhamento Ryleigh pelo vapor d'água, oscilaram de 0,30 a 0,47.
The short wave solar radiation (ROC) that passes through the atmosphere depends mainly on the atmospheric turbidity and cloud cover. A study of the variability of the optical depth of the atmosphere over Maceió, in the State of Alagoas, using incoming solar radiation in the top of the atmosphere and surface, was carried through long wave radiation (ROL), cloud covering, precipitable water and precipitation using the NCAR/NCEP re-analysis data set. The annual cycle of the optical depth obtained with these data, was compared through observed global radiation from the UFAL meteorology department's data set for the period from 1997 to 1999. In the period from January to June of the year 1997, Maceio had about 60 to 80 per cent of cloud cover and during the period from April to July (rainy season in that location) it had highest cloud cover of around 70 to 80 per cent, increasing the attenuation. The highest ROC concentration occurred in the year 1999 (La Niña conditions) with a maximum of 10 mm day-1 precipitation. The values of transmittance totalizer calculated in function of the Ryleigh scattering for the water vapor had oscillated from 0.30 to 0.47.
2667 downloads
Showing
itens per page
Page
of 2
Next
Statistics of
Send result
Sem resultados
No documents were found for your search
Glossary and search help
You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.
For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:ti:dengue and publication_year:2015 and aff_country:Brasil
See below the complete list of search indexes that can be used:
Index code | Element |
---|---|
ti | article title |
au | author |
kw | article keywords |
subject | subject (title words, abstract and keywords) |
ab | abstract |
ta | journal short title (e.g. Cad. Saúde Pública) |
journal_title | journal full title (e.g. Cadernos de Saúde Pública) |
la | publication language code (e.g. pt - Portuguese, es - Spanish) |
type | document type |
pid | publication identifier |
publication_year | publication year of publication |
sponsor | sponsor |
aff_country | country code of the author's affiliation |
aff_institution | author affiliation institution |
volume | article volume |
issue | article issue |
elocation | elocation |
doi | DOI number |
issn | journal ISSN |
in | SciELO colection code (e.g. scl - Brasil, col - Colômbia) |
use_license | article usage license code |