Search | SciELO

Need help?

Add field +

Search history

No documents were found for your search

Results: 30

au:LOBATO, MARIA INES

Filters

Collection + Options

All
Brazil

28
Public Health

2

Journal + Options

All
Brazilian Journal of Psychiatry

10
Revista de Psiquiatria do Rio Grande do Sul

6
Ciência & Saúde Coletiva

4
Trends in Psychiatry and Psychotherapy

4
Archives of Clinical Psychiatry (São Paulo)

1
Ciência Rural

1
Memórias do Instituto Oswaldo Cruz

1
Revista Brasileira de Ginecologia e Obstetrícia

1
Revista Brasileira de Ortopedia

1
Revista Brasileira de Reumatologia

1

Show all...

Language

All
Portuguese

16

Publication Year + Options

All
2021

5
2005

4
2006

4
2009

3
2010

3
2004

2
2007

2
2013

2
2017

2
2016

1
2020

1
2022

1

SciELO Thematic Areas + Options

All
Health Sciences

29
Agricultural Sciences

1
Biological Sciences

1

WoS Subject Categories + Options

All
Psychiatry

21
Acoustics

6
Health

4
Environmental

2
Medicine

2
Occupational

2
Policy

2
Public

2
Services

2
Agronomy

1
General

1
Gynecology

1
Internal

1
Obstetrics

1
Orthopedics

1

Show all...

WoS Citation Index + Options

All
Science Citation Index Expanded

14
Social Sciences Citation Index

12

Citables and non citables + Options

All
Citable

24
Non citable

6

Type of Literature + Options

All
Article

22
Letter

6
Case report

2

Order by

Page of 2 Next

Select this page

Print | Send to email | Export |

Facebook
Twitter
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

0 Selected itens

List all
Erase all

Risk of neutropenia among clozapine users and non-users: results from 5,847 patients
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Goldani, André Akira Sueno

; Rabelo-da-Ponte, Francisco Diego

; Feiten, Jacson Gabriel

; Lobato, Maria Ines R.

; Belmonte-de-Abreu, Paulo S.

; Gama, Clarissa S.

Brazilian Journal of Psychiatry

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2022, Volume 44 N. 1 Pages 21 - 25

Abstract: En | Text: En | PDF: En

Objective: Clozapine is underprescribed due to neutropenia risk. Blood tests every 3 months in those on continuous treatment for > 1 year who have never had an absolute neutrophil count (ANC) < 2,000/µL has been proposed as a monitoring strategy; however, there are no South American data to support this recommendation. This study sought to investigate whether clozapine use and other variables could explain the occurrence of ANC < 1,000/µL in patients with severe mental disorders. Methods: A total of 5,847 subjects were included, 1,038 on clozapine. We performed a Cox regression considering the outcome as ANC < 1,000/µL at any time point. Predictors were sex, age, ethnicity, clozapine use, ANC > 2,000/µL during the first year of blood monitoring, and presence of a severe medical condition. Results: In the Cox regression model, ethnicity (white) (hazard ratio [HR] 0.53; 95%CI 0.29-0.99, p < 0.05) and ANC > 2,000/µL (HR 0.04; 95%CI 0.01-0.10, p < 0.001) were protective factors, while presence of a severe medical condition (HR 69.35; 95%CI 37.45-128.44, p < 0.001) was a risk factor for ANC < 1,000/µL. Other variables were not significant, including clozapine use (HR 1.33; 95%CI 0.74-2.39, p > 0.05). Conclusions: These findings suggest that clozapine does not increase the risk of neutropenia in subjects with ANC > 2,000/µL during the first year of use and in the absence of a severe medical condition. These results could help guide clinical and public-health decisions regarding clozapine blood monitoring guidelines.

https://doi.org/10.1590/1516-4446-2021-1765

Tobacco use among transgender and gender non-binary youth in Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Fontanari, Anna Martha Vaitses

; Churchill, Siobhan

; Schneider, Maiko Abel

; Soll, Bianca

; Costa, Angelo Brandelli

; Lobato, Maria Inês Rodrigues

Ciência & Saúde Coletiva

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 26 Suppl. 3 Pages 5281 - 5292

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Jovens transgêneros e não-binários são particularmente vulneráveis ao tabagismo e suscetíveis a seus malefícios a saúde. Ou seja, esses grupos estão em especial risco para começar a fumar e, após o início, tendem a apresentar resultados piores quando comparados a seus pares cisgêneros. Sendo assim, o presente estudo tem como objetivo avaliar fatores associados ao uso do tabaco em jovens transgêneros e não-binários. Jovens brasileiros, com idade entre 16 e 25 anos, que se identificam como transgêneros ou não-binários responderam um questionário on-line. Uma Regressão de Poisson com variância robusta foi realizada para predizer o consumo de cigarros com base em fatores individuais e ambientais. 14,1% de 206 jovens relataram fumar cigarros diariamente, enquanto 9,3% dos participantes revelaram fumar cigarros eletrônicos ocasionalmente. Uso de drogas, falta de suporte social, experiências de privação, discriminação, espera para procedimentos médicos de afirmação de gênero e evasão escolar foram associados ao consumo de cigarros entre jovens transgêneros e não-binários brasileiros. Sendo assim, os fatores individuais e contextuais citados devem receber especial enfoque no planejamento de intervenções de prevenção e interrupção do tabagismo voltados a jovens transgêneros e não-binários brasileiros.

Abstract Transgender and gender non-binary youth are particularly vulnerable to tobacco smoking and susceptible to smoking adverse health outcomes. That is, they are in special risk to start smoking and, after starting, they may face worse outcomes when comparing to their cisgender peers. Therefore, the present study aims to evaluate factors associated with tobacco use among transgender and gender non-binary youth. Brazilian youth aged 16 to 25 who identify as transgender or gender non-binary answered an online questionnaire. Poisson regression with robust variance was run to predict smoking cigarettes based on individual and environmental factors. 14.1% of 206 youth reported smoking cigarettes daily, whereas 9.3% of participants reported smoking e-cigarettes occasionally. Drug use, lack of social support, deprivation, discrimination, the wait for medical gender-affirming procedures and being outside school were associated with smoking cigarettes. Contextual and individual factors should be further explored in causal analysis and taken into consideration when planning smoking prevention and cessation interventions for transgender and gender non-binary youth.

https://doi.org/10.1590/1413-812320212611.3.35272019 3 downloads

Tobacco use among transgender and gender non-binary youth in Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Fontanari, Anna Martha Vaitses

; Churchill, Siobhan

; Schneider, Maiko Abel

; Soll, Bianca

; Costa, Angelo Brandelli

; Lobato, Maria Inês Rodrigues

Ciência & Saúde Coletiva

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 26 Suppl. 3 Pages 5281 - 5292

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212611.3.35272019

Impacto do estresse de minoria em sintomas depressivos, ideação suicida e tentativa de suicídio em pessoas trans
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Chinazzo, Ítala Raymundo

; Lobato, Maria Inês Rodrigues

; Nardi, Henrique Caetano

; Koller, Silvia Helena

; Saadeh, Alexandre

; Costa, Angelo Brandelli

Ciência & Saúde Coletiva

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 26 Suppl. 3 Pages 5045 - 5056

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O estresse de minoria aborda a relação entre preconceito (percebido, antecipado e internalizado) e saúde mental em pessoas pertencentes a grupos minoritários, assim como fatores de proteção aos estressores. Este trabalho avaliou a prevalência de sintomas depressivos, ideação suicida e tentativa de suicídio em pessoas trans brasileiras, e sua relação com estresse de minoria, passabilidade, apoio social e apoio à identidade trans. Participaram 378 pessoas, por meio de questionário respondidos on-line e nos serviços hospitalares a que frequentavam. Desses, 67,20% apresentaram sintomas depressivos, 67,72% ideação suicida e 43,12% tentativa de suicídio. Foram realizadas três análises de regressão de Poisson, em dois passos, conforme os desfechos. Nos três desfechos houve associação positiva com o preconceito internalizado e negativa com o apoio social, sendo essas as únicas associações na tentativa de suicídio. Nos sintomas depressivos e na ideação suicida, também se associou positivamente o preconceito antecipado e negativamente a passabilidade e o apoio à identidade trans. Percebe-se a vulnerabilidade das pessoas trans para os desfechos negativos de saúde mental e a importância de enfrentar o preconceito em nível individual e social, assim como promover o apoio social e à identidade trans.

Abstract Minority stress comprehends the relationship between prejudice (perceived, anticipated and internalized) and mental health in people belonging to minority groups, as well as protective factors for stressors. This study evaluated the prevalence of depressive symptoms, suicidal ideation and attempted suicide in Brazilian trans people, and it`s relationship with minority stress, passability, social support and trans identity support. 378 people participated through a questionnaire answered online and in the hospital services they attended. Of these, 67.20% had depressive symptoms, 67.72% suicidal ideation and 43.12% attempted suicide. Three Poisson regression analyzes were performed in two steps, according to the outcomes. In the three outcomes there was a positive association with internalized prejudice and a negative association with social support, which were the only associations in the suicide attempt. Depressive symptoms and suicidal ideation were also positively associated with anticipated prejudice and negatively passability and support for trans identity. The vulnerability of transgender people to negative mental health outcomes and the importance of addressing prejudice on an individual and social level, as well as promoting social support and transgender identity support are perceived.

https://doi.org/10.1590/1413-812320212611.3.28532019

Impacto do estresse de minoria em sintomas depressivos, ideação suicida e tentativa de suicídio em pessoas trans
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Chinazzo, Ítala Raymundo

; Lobato, Maria Inês Rodrigues

; Nardi, Henrique Caetano

; Koller, Silvia Helena

; Saadeh, Alexandre

; Costa, Angelo Brandelli

Ciência & Saúde Coletiva

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 26 Suppl. 3 Pages 5045 - 5056

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212611.3.28532019 1 downloads

Gender dysphoria: prejudice from childhood to adulthood, but no impact on inflammation. A cross-sectional controlled study
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Real, André Gonzales

; Fontanari, Anna Martha Vaitses

; Costa, Angelo Brandelli

; Soll, Bianca Machado Borba

; Bristot, Giovana

; de Oliveira, Larissa Fagundes

; Kamphorst, Ana Maria

; Schneider, Maiko Abel

; Lobato, Maria Inês Rodrigues

Trends in Psychiatry and Psychotherapy

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2021, Volume 43 N. 1 Pages 37 - 46

Abstract: En | Text: En | PDF: En

Abstract Introduction Gender dysphoria (GD) is characterized by a marked incongruence between experienced gender and one’s gender assigned at birth. Transsexual individuals present a higher prevalence of psychiatric disorders when compared to non-transsexual populations, and it has been proposed that minority stress, i.e., discrimination or prejudice, has a relevant impact on these outcomes. Transsexuals also show increased chances of having experienced maltreatment during childhood. Interleukin (IL)-1β, IL-6, IL-10 and tumor necrosis factor-alpha (TNF-α) are inflammatory cytokines that regulate our immune system. Imbalanced levels in such cytokines are linked to history of childhood maltreatment and psychiatric disorders. We compared differences in IL-1β, IL-6, IL-10 and TNF-α levels and exposure to traumatic events in childhood and adulthood in individuals with and without GD (DSM-5). Methods Cross-sectional controlled study comparing 34 transsexual women and 31 non-transsexual men. They underwent a thorough structured interview, assessing sociodemographic information, mood and anxiety symptoms, childhood maltreatment, explicit discrimination and suicidal ideation. Inflammatory cytokine levels (IL-1β, IL-6, IL-10 and TNF-α) were measured by multiplex immunoassay. Results Individuals with GD experienced more discrimination (p = 0.002) and childhood maltreatment (p = 0.046) than non-transsexual men. Higher suicidal ideation (p < 0.001) and previous suicide attempt (p = 0.001) rates were observed in transsexual women. However, no differences were observed in the levels of any cytokine. Conclusions These results suggest that transsexual women are more exposed to stressful events from childhood to adulthood than non-transsexual men and that GD per se does not play a role in inflammatory markers.

https://doi.org/10.47626/2237-6089-2020-0007 412 downloads

Intraosseous Neurothekeoma of the Hand in a 16-year-old Boy
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Cabral, João José Lobato Guimarães Ferreira

; Balacó, Inês Maria Spencer

; Alves, Cristina Marta da Gama Gomes

; Matos, António Gabriel de Almeida

Revista Brasileira de Ortopedia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2020, Volume 55 N. 1 Pages 125 - 129

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Os tumores dos tecidos moles são raros em idade pediátrica. Descrito pela primeira vez 1969 como um mixoma da bainha nervosa, o neurotequeoma é uma lesão tumoral benigna com presumível origem na bainha nervosa. Ocorre maioritariamente em crianças do sexo feminino e apresenta-se como uma massa de crescimento lento, subcutânea, assintomática e sem alteração da pigmentação local. Localiza-se predominantemente na cabeça, no pescoço, e nas extremidades dos membros superiores. Os autores apresentam um caso clínico de um jovem de 16 anos do sexo masculino com massa tumoral com origem na bainha nervosa no 4º metacarpo esquerdo, intraóssea e recidivada após ressecção cirúrgica 2 anos antes do estudo. Foi feita ressecção marginal da massa tumoral localizada sobre a região distal do quarto metacarpo e curetagem da falange proximal e preenchimento com enxerto ósseo autólogo corticoesponjoso. O paciente apresentou uma evolução clínica pós-operatória favorável, sem queixas álgicas e sem limitações da mobilidade dos dedos da mão. Radiologicamente, foi observado preenchimento trabecular progressivo da falange proximal do quarto metacarpo. Aos 17 meses de seguimento, o paciente se encontra assintomático e não apresenta quaisquer sinais de recidiva. Com a descrição deste caso, os autores pretendem aumentar a familiaridade com essa rara patologia, seu diagnóstico e tratamento.

Abstract Soft-tissue tumors are rare in the pediatric population. First described in 1969 as myxoma of the nerve sheath, the neurothekeoma is a benign tumor lesion with presumable origin in the nerve sheath. It occurs mainly in female children and presents as a mass of slow, subcutaneous growth, asymptomatic and without alteration of the local pigmentation. It is predominantly located in the head, neck, and extremities of the upper limbs. This report presents the case of a 16-year-old male with a tumor mass originating from the nerve sheath in the 4th left metacarpal, intraosseous, and relapsed after previous surgical resection 2 years before this observation. A marginal resection of the tumor mass was performed on the distal region of the fourth metacarpal, followed by curettage of the proximal phalanx and filling with structural autologous bone graft. The patient maintained a favorable postoperative clinical evolution, without local pain or range of motion limitation in his fingers. Radiologically, a progressive trabecular filling of the proximal phalanx of the fourth metacarpal was observed. At 17 months of follow-up, the patient is asymptomatic and shows no signs of relapse. The description of this case serves to increase the familiarity with this rare pathology, and aid its diagnosis and treatment.

https://doi.org/10.1016/j.rbo.2018.02.006 512 downloads

Serum concentrations of brain-derived neurotrophic factor in patients diagnosed with gender dysphoria undergoing sex reassignment surgery
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Schneider, Maiko A.

; Andreazza, Tahiana

; Fontanari, Anna Martha V.

; Costa, Angelo B.

; Silva, Dhiordan C. da

; Aguiar, Bianca W. de

; Massuda, Raffael

; Pedrini, Mariana

; Gama, Clarissa S.

; Schwarz, Karine

; Kauer-Sant'Anna, Marcia

; Lobato, Maria Ines R.

Trends in Psychiatry and Psychotherapy

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2017, Volume 39 N. 1 Pages 43 - 47

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: O transexualismo (CID-10) é uma condição caracterizada por forte e persistente dissociação com o gênero atribuído. A cirurgia de redesignação sexual (CRS) e a terapia hormonal (TH) permitem que indivíduos transexuais se sintam mais congruentes com seu gênero e, por isso, têm desempenhado papel importante nos últimos 70 anos. O fator neurotrófico derivado do cérebro (BDNF) parece desempenhar um papel fundamental na recuperação do trauma cirúrgico agudo e vulnerabilidade ambiental à psicopatologia. Nós hipotetizamos que o BDNF pode ser um biomarcador de alívio do sofrimento de incongruência de gênero pós-CRS. Objetivos: Mensurar os níveis séricos de BDNF no pré e pós-operatório em indivíduos transexuais como biomarcador de alívio de estresse relacionado à incongruência de gênero após a CRS. Métodos: Trinta e duas pessoas transexuais masculino para feminino submetidas a cirurgia e tratamento hormonal foram selecionadas de nossa amostra inicial. O nível sérico de BDNF foi avaliado antes e depois da CRS pela técnica ELISA. O tempo decorrido entre as coletas de sangue pré e pós-CRS foi medido. Resultados: Não houve diferença significativa nos níveis de BDNF pré e pós-CRS ou em relação ao tempo decorrido entre a CRS e a coleta. Conclusão: O alívio do sofrimento relacionado à incongruência de gênero pós-CRS não pode ser avaliado apenas pelo BDNF. Soluções cirúrgicas podem não fornecer uma solução rápida para o sofrimento associado ao transexualismo, e a CRS pode servir como um passo em direção à, em vez de conclusão da, construção da identidade de gênero de uma pessoa.

Abstract Introduction: Transsexualism (ICD-10) is a condition characterized by a strong and persistent dissociation with one's assigned gender. Sex reassignment surgery (SRS) and hormone therapy provide a means of allowing transsexual individuals to feel more congruent with their gender and have played a major role in treatment over the past 70 years. Brain-derived neurotrophic factor (BDNF) appears to play a key role in recovery from acute surgical trauma and environmentally mediated vulnerability to psychopathology. We hypothesize that BDNF may be a biomarker of alleviation of gender incongruence suffering. Objectives: To measure preoperative and postoperative serum BDNF levels in transsexual individuals as a biomarker of alleviation of stress related to gender incongruence after SRS. Methods: Thirty-two male-to-female transsexual people who underwent both surgery and hormonal treatment were selected from our initial sample. BDNF serum levels were assessed before and after SRS with sandwich enzyme linked immunosorbent assay (ELISA). The time elapsed between the pre-SRS and post-SRS blood collections was also measured. Results: No significant difference was found in pre-SRS or post-SRS BDNF levels or with relation to the time elapsed after SRS when BDNF levels were measured. Conclusion: Alleviation of the suffering related to gender incongruence after SRS cannot be assessed by BDNF alone. Surgical solutions may not provide a quick fix for psychological distress associated with transsexualism and SRS may serve as one step toward, rather than as the conclusion of, construction of a person's gender identity.

https://doi.org/10.1590/2237-6089-2016-0033 3115 downloads

Incidence of tuberculosis among patients with rheumatoid arthritis using TNF blockers in Brazil: data from the Brazilian Registry of Biological Therapies in Rheumatic Diseases (Registro Brasileiro de Monitoração de Terapias Biológicas - BiobadaBrasil)
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Yonekura, Claudia Leiko

; Oliveira, Rene Donizeti Ribeiro

; Titton, David C.

; Ranza, Roberto

; Ranzolin, Aline

; Hayata, André L.

; Duarte, Ângela

; Silveira, Inês G.

; Carvalho, Hellen M. da S. de

; Moraes, Júlio C. Bertacini de

; Abreu, Mirhelen Mendes de

; Valim, Valéria

; Bianchi, Washington

; Brenol, Claiton Viegas

; Pereira, Ivanio A.

; Costa, Izaias

; Macieira, José C.

; Miranda, José R.S.

; Guedes-Barbosa, Luiz S.

; Bertolo, Manoel B.

; Sauma, Maria Fátima Lobato da C.

; Silva, Marília B.G.

; Freire, Marlene

; Scheinberg, Morton A.

; Toledo, Roberto A.

; Oliveira, Sheila K.F.

; Fernandes, Vander

; Pinheiro, Marcelo M.

; Castro, Glaucio

; Vieira, Walber Pinto

; Baaklini, Cesar Emile

; Ruffino-Netto, Antonio

; Pinheiro, Geraldo da Rocha Castelar

; Laurindo, Ieda Maria Magalhães

; Louzada-Junior, Paulo

Revista Brasileira de Reumatologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2017, Volume 57 Suppl. 2 Pages s477 - s483

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivos Avaliar incidência de tuberculose e triagem para tuberculose latente em brasileiros com artrite reumatoide em uso de agentes biológicos na prática clinica. Pacientes e métodos Estudo de coorte com dados do Registro Brasileiro de Monitoração de Terapias Biológicas (BiobadaBrasil), de 01/2009 a 05/2013, abrangeu 1.552 tratamentos, 415 somente com drogas modificadoras do curso da doença (MMCDs) sintéticas, 942 MMCDs sintéticas em associação com anti-TNF (etanercepte, infliximabe, adalimumabe) e 195 MMCDs sintéticas em associação com outros biológicos (abatacepte, rituximabe e tocilizumabe). Avaliaram-se ocorrência de tuberculose, tempo de exposição às drogas e triagem para TB. Análise estatística: teste t não pareado e teste de Fisher bicaudal; p < 0,05. Resultados O tempo de exposição dos controles foi de 981 pacientes-ano, do grupo de anti-TNF foi de 1.744 pacientes-ano (adalimumabe = 676, infliximabe = 547 e etanercepte = 521 pacientes-ano) e o de outros biológicos de 336 pacientes-ano. A incidência de TB foi de 1,01/1.000 pacientes-ano nos controles e de 2,87 pacientes-ano nos usuários de anti-TNF (adalimumabe = 4,43/1.000 pacientes-ano; etanercepte = 1,92/1.000 pacientes-ano e infliximabe = 1,82/1.000 pacientes-ano). Não houve casos de tuberculose no grupo de outros biológicos. O tempo médio de exposição até a ocorrência de tuberculose foi de 27(11) meses para o grupo anti-TNF. Conclusões A incidência de tuberculose foi maior nos usuários de MMCDs sintéticas e anti-TNF do que nos usuários de MMCDs sintéticas e de MMCDs sintéticas e biológicos não anti-TNF, e também mais tardia, sugerindo infecção durante o tratamento, e não falha na triagem.

Abstract Objectives To assess the incidence of tuberculosis and to screen for latent tuberculosis infection among Brazilians with rheumatoid arthritis using biologics in clinical practice. Patients and methods This cohort study used data from the Brazilian Registry of Biological Therapies in Rheumatic Diseases (Registro Brasileiro de Monitoração de Terapias Biológicas - BiobadaBrasil), from 01/2009 to 05/2013, encompassing 1552 treatments, including 415 with only synthetic disease-modifying anti-rheumatic drugs, 942 synthetic DMARDs combined with anti-tumor necrosis factor (etanercept, infliximab, adalimumab) and 195 synthetic DMARDs combined with other biologics (abatacept, rituximab and tocilizumab). The occurrence of tuberculosis and the drug exposure time were assessed, and screening for tuberculosis was performed. Statistical analysis: Unpaired t-test and Fisher's two-tailed test; p < 0.05. Results The exposure times were 981 patient-years in the controls, 1744 patient-years in the anti-TNF group (adalimumab = 676, infliximab = 547 and etanercept = 521 patient-years) and 336 patient-years in the other biologics group. The incidence rates of tuberculosis were 1.01/1000 patient-years in the controls and 2.87 patient-years among anti-TNF users (adalimumab = 4.43/1000 patient-years; etanercept = 1.92/1000 patient-years and infliximab = 1.82/1000 patient-years). No cases of tuberculosis occurred in the other biologics group. The mean drug exposure time until the occurrence of tuberculosis was 27(11) months for the anti-TNF group. Conclusions The incidence of tuberculosis was higher among users of synthetic DMARDs and anti-TNF than among users of synthetic DMARDs and synthetic DMARDs and non-anti-TNF biologics and also occurred later, suggesting infection during treatment and no screening failure.

https://doi.org/10.1016/j.rbre.2017.05.005 3602 downloads

10.

Heat stroke during long-term clozapine treatment: should we be concerned about hot weather?
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Hoffmann, Maurício Scopel

; Oliveira, Lucas Mendes

; Lobato, Maria Inês Rodrigues

; Belmonte-de-Abreu, Paulo

Trends in Psychiatry and Psychotherapy

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2016, Volume 38 N. 1 Pages 56 - 59

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo Descrever o caso de um paciente com esquizofrenia em tratamento com clozapina acometido por um episódio de heat stroke. Descrição do caso Durante uma onda de calor em janeiro e fevereiro de 2014, um paciente com esquizofrenia em tratamento com clozapina foi inicialmente encaminhado para diagnóstico diferencial de infecção sistêmica e síndrome neuroléptica maligna, tendo obtido o diagnóstico final de heat stroke, tratado com controle de temperatura corporal e hidratação. Comentários Este relato de caso tem como objetivo alertar os clínicos para este diagnóstico diferencial, que pode surgir com mais frequência à medida que as temperaturas globais continuarem a aumentar, e também destacar a importância da realização de um diagnóstico mais acurado, que possa melhorar as decisões de tratamento e os desfechos clínicos para os pacientes.

Objective To describe the case of a patient with schizophrenia on clozapine treatment who had an episode of heat stroke. Case description During a heat wave in January and February 2014, a patient with schizophrenia who was on treatment with clozapine was initially referred for differential diagnose between systemic infection and neuroleptic malignant syndrome, but was finally diagnosed with heat stroke and treated with control of body temperature and hydration. Comments This report aims to alert clinicians take this condition into consideration among other differential diagnoses, especially nowadays with the rise in global temperatures, and to highlight the need for accurate diagnosis of clinical events during pharmacological intervention, in order to improve treatment decisions and outcomes.

https://doi.org/10.1590/2237-6089-2015-0066 2426 downloads

11.

rTMS as an add-on treatment for resistant obsessive-compulsive symptoms in patients with schizophrenia: report of three cases
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Mendes-Filho, Vauto Alves

; Belmonte-de-Abreu, Paulo

; Pedrini, Mariana

; Cachoeira, Carolina Tosetto

; Lobato, Maria Inês Rodrigues

Brazilian Journal of Psychiatry

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2013, Volume 35 N. 2 Pages 211 - 211

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1516-4446-2012-1035 2224 downloads

12.

Impairment in psychosocial functioning in patients with different subtypes of eating disorders
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Moser, Carolina Meira

; Lobato, Maria Inês Rodrigues

; Rosa, Adriane R.

; Thomé, Emi

; Ribar, Julia

; Primo, Lucas

; Santos, Ana Carolina Faedrich dos

; Brunstein, Miriam Garcia

Trends in Psychiatry and Psychotherapy

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2013, Volume 35 N. 2 Pages 111 - 118

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Avaliar o funcionamento psicossocial de pacientes com subtipos restritivo e purgativo de transtorno alimentar (TA). MÉTODOS: Quarenta e quatro pacientes adultas com TA foram divididas em grupos restritivo (RP) e purgativo (PP) conforme a presença de sintomas purgativos. O funcionamento foi avaliado com a Functioning Assessment Short Test (FAST) e a Global Assessment of Functioning Scale (GAF). RESULTADOS: Não houve diferenças nos escores totais nem nos domínios da FAST entre os grupos RP (39,58±11,92) e PP (45,75±11,75) (p = 0,19). No entanto, o grupo PP demonstrou maior prejuízo funcional no domínio finanças (p < 0,01). RP e PP foram semelhantes em comorbidade com transtornos de humor, sintomas depressivos e sintomas psiquiátricos em geral. CONCLUSÕES: As semelhanças encontradas entre os grupos PP e RP no funcionamento geral e nos domínios autonomia, cognição, trabalho, relacionamentos interpessoais e lazer parecem refletir o uso de uma escala objetiva que corresponde à impressão clínica. De fato, é necessário cautela ao avaliar funcionamento psicossocial em pacientes com TA com escalas autoaplicáveis, porque estas costumam refletir a natureza egossintônica dos sintomas comumente observados nesses pacientes, especialmente no subtipo restritivo.

OBJECTIVE: To examine psychosocial functioning in eating disorder (ED) patients with restrictive and purgative subtypes. METHOD: Forty-four adult female patients with a diagnosis of ED were divided into restrictive (RP) and purgative (PP) groups according the presence of purgative symptoms. Functioning was assessed using the Functioning Assessment Short Test (FAST) and the Global Assessment of Functioning Scale (GAF). RESULTS: No differences were found in total FAST scores or in specific domains between the RP (39.58±11.92) and PP (45.75±11.75) groups (p = 0.19). However, PP showed more severe functional impairment than RP in the financial domain (p < 0.01). There were no differences in comorbidity with mood disorders, depressive symptoms, or general psychiatric symptoms between the two ED subtypes. CONCLUSIONS: The similarities found between PP and PR in overall functioning and in autonomy, cognition, work, interpersonal relationships, and leisure seem to reflect the use of an objective scale that corresponds to the clinical impression. In fact, the assessment of psychosocial functioning in ED patients using self-report instruments requires careful consideration because results may reflect the egosyntonic nature of symptoms commonly observed in these patients, particularly in the restrictive subtype.

5020 downloads

13.

HIV-1 RNA detection in the amniotic fluid of HIV-infected pregnant women
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Lobato, Ana Christina

; Aguiar, Regina Amélia

; Aleixo, Agdemir Waléria

; Andrade, Beatriz Amélia

; Cavallo, Ines Katherina

; Kakehasi, Fabiana Maria

; Pinto, Jorge Andrade

; Melo, Victor Hugo

Memórias do Instituto Oswaldo Cruz

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2010, Volume 105 N. 5 Pages 720 - 721

Abstract: En | Text: En | PDF: En

This study is aimed at evaluating the potential to detect human immunodeficiency virus (HIV) in amniotic fluid (AF) collected at delivery from 40 HIV-positive pregnant women. Thirty patients had a plasma viral load (VL) below 1,000 copies/mL at delivery. VL was positive in three AF samples. No significant association was found between the HIV-1 RNA in AF and the maternal plasma samples. There was no HIV vertical transmission detected.

2603 downloads

14.

Improvement of schizophrenia negative and positive symptoms with amantadine as add-on therapy to antipsychotics: a case series
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Gama, Clarissa Severino

; Lucena, David De

; Cruz, Cíntia

; Lobato, Maria Inês

; Belmonte-de-Abreu, Paulo Silva

Brazilian Journal of Psychiatry

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2010, Volume 32 N. 2 Pages 193 - 194

Abstract: En | Text: En | PDF: En

3070 downloads Cited 1 time in SciELO

15.

A falácia da adequação da cobertura dos Centros de Atenção Psicossocial no estado do Rio Grande do Sul
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Gonçalves, Veralice Maria

; Candiago, Rafael Henriques

; Saraiva, Sérgio da Silva

; Lobato, Maria Inês Rodrigues

; Belmonte-de-Abreu, Paulo Silva

Revista de Psiquiatria do Rio Grande do Sul

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2010, Volume 32 N. 1 Pages 16 - 18

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Introdução: A análise dos resultados da expansão da rede de atenção à saúde mental para a população brasileira tem utilizado como medida de desfecho o indicador de cobertura dos Centros de Atenção Psicossocial (CAPS), que considera adequada a existência de um CAPS para cada 100 mil habitantes. O Rio Grande do Sul encontra-se classificado em terceiro lugar no ranking nacional, com índice de 0,7 CAPS/100.000 habitantes. Este estudo objetivou testar a variabilidade de cobertura de cada região para verificar se esse índice global representava as realidades regionais. Método: Foram utilizados dados do Cadastro Nacional de Estabelecimentos de Saúde (CNES) e dados populacionais do ano de 2009 disponibilizados pelo site do Departamento de Informática do Sistema Único de Saúde do Ministério da Saúde. Foram calculados os indicadores de cobertura para as 19 regionais de saúde, sendo gerado índice de cobertura resultante da razão entre o indicador observado e o esperado de acordo com a população de cada região geográfica analisada. Resultados: Analisada a variabilidade de cobertura de cada região, foi evidenciada a ocorrência de sete regiões com cobertura insuficiente, representando 49% da população do estado com cobertura inadequada. Conclusão: O estudo demonstrou que o uso do índice global é falacioso, pois não representa as realidades regionais, sendo que cerca de metade das regiões com excesso de cobertura mascaram as regiões deficientes. Isso sugere que as análises de cobertura devem ser realizadas por áreas geográficas para identificar carências regionais e fornecer subsídios para a extensão da rede de forma igualitária para usuários de diferentes regiões do estado.

Introduction: Analysis of the results of the ongoing expansion of the Brazilian public mental health care network has used the indicator of coverage offered by Psychosocial Care Centers (Centros de Atenção Psicossocial, CAPS), which considers the rate of one CAPS per 100,000 inhabitants to be adequate, as its outcome measure. The state of Rio Grande do Sul ranks third in nationwide CAPS coverage standings, with 0.7 centers per 100,000 inhabitants. The present study sought to assess the variability of coverage in different regions in order to verify the representativeness of the overall coverage rate. Method: We used data collected from the National Database of Health Facilities (Cadastro Nacional de Estabelecimentos de Saúde, CNES) and 2009 population data made available at the website of the Ministry of Health Department of Information Technology. We calculated 19 coverage indicators, one for each health region, and computed a coverage rate based on the ratio between the actual indicator and the expected indicator according to the population of each region. Results: Analysis of the variability of coverage for each region showed that seven regions had inadequate coverage, with 49% of the state population receiving inadequate coverage. Conclusion: This study showed that the use of an overall rate for mental health care coverage can be considered a fallacy, as it fails to represent regional realities; roughly half of the regions with excessive coverage masked the regions with poor coverage. This finding suggests that analysis of care coverage must be broken down into geographic areas, in order to identify regional needs and provide support for equal expansion of the community mental health care network for users living in different geographic areas.

3082 downloads Cited 4 times in SciELO

Showing

itens per page

Page of 2 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »