The present communication reports the isolation and identification of three lignans from metanolic root extracts of Strychnos guianensis (Aublet) Mart.: olivil (1), cycloolivil (2) and the unknown derivative cycloolivil carbonate (3). From hexane extracts was identified a long chain fatty acid mixture and the triterpene lupeol. The analyses were based on chromatographic and spectroscopy techniques (IR, MS, GC/MS, ¹H-NMR and 13C-NMR, 1D (BB, DEPT 135) and 2D (¹H, ¹ H-COSY, ¹H, 13C-COSY, ¹H, 13C-COSY-LR, HMQC, HMBC and NOESY) and comparison with literature data.

Gustavia augusta is used in the folk medicine against leishmaniosis and showed anti-inflammatory action. The phytochemical studies of the plant stem bark have led to the isolation of (22E)-stigmasta-7,22-dien-3beta-ol, 24alpha(S)-ethyl-5alpha-colesta-7,trans-22-dien-3-one, D-friedoolean-14-en-3beta-ol, D-friedoolean-14-en-3-one and D-friedoolean-14-en-3alpha-ol along with stigmasterol, alpha-amyrin, beta-amyrin, lupeol, 3alpha-hidroxi-lupeol and betulinic acid. The structures of these compounds were identified by IR, GC/MS, ¹H and 13C NMR spectral analysis and comparison with literature data.

Dos extratos benzênico e clorofórmico da madeira de Swartzia brachyrachisHarms var. brachyrachis foram isolados, por métodos cromatográficos, uma isoflavona inédita (7,4'—diidroxi -5,3'5'-trimetoxi-6-metilisoflavona), denominada brachyrachisina, c um glicosídio (3-O-β-D-glicopiranosilsitosterol). As estruturas foram elucidadas através de análises espectroscópicas.

From the wood benzene and chloroform extracts of Swartzia brachyrachis Harms var.brachyrachis were isolated, by chromatografph methods, an undocumented isoflavone (7,4'-dihydroxy-5,3',5'—trimethoxy-6-methylisoflavone) named brachyrachisine and a glucoside (3-O-β-D-glucopyranosylsitosterol). The structures were elucidated by spectroscopic analysis.