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Determinación y monitoreo de puntos críticos de ruido urbano considerando múltiples factores in situ
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Romero-Villacrés, María Fernanda

; Rivera-Velásquez, María Fernanda

; Cisneros-Vaca, César Ramiro

; Naranjo-Polo, Ángel Andrés

Revista Digital Novasinergia

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jun 2024, Volume 7 N. 1 Pages 67 - 87

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: The present research determines and monitors critical points through a multi-criteria analysis in the urban center of the city of Riobamba for its subsequent representation in thematic noise maps. For the selection of critical points, a pondering matrix was made considering the following factors: citizen perception surveys, urban bus routes, proximity to public and private institutions, parks and initial measurements. The monitoring was carried out at 25 prioritized points from 7:00 am to 7:00 pm; the values obtained correspond to the minimum Leq(A), the Leq(A), and the maximum Leq(A). The main results indicates that the main source of noise are the popular markets, on Mondays, Tuesdays and Wednesdays, with Leq(A) ranges above 70 dB(A). It is observed that at all points the Leq(A) values exceed the national permissible limit at some time during the day. The noise maps were made using the Kriging method, through the Gaussian semivariogram model, for all days, with the exception of Wednesday when the rational quadratic semivariogram model was used. For these models the RMSE and ASE values indicate high model quality.

Resumen: La presente investigación determina y monitorea puntos críticos, a través de un análisis multricriterio, en el centro urbano de la Ciudad de Riobamba, para la posterior representación dentro de mapas temáticos de ruido. Para la selección de puntos críticos se realizó una matriz de ponderación considerando los siguientes factores: encuestas de percepción ciudadana, rutas de los buses urbanos, cercanías a instituciones públicas y privadas, parques y mediciones iniciales. Los monitoreos fueron realizados en 25 puntos priorizados desde las 7H00 hasta las 19H00, los valores obtenidos corresponden al Leq(A) mínimo, al Leq(A), y al Leq(A) máximo. Los resultados principales indican que la fuente primordial de ruido son los mercados populares, los días lunes, martes, y miércoles, con de rangos de Leq(A) superiores a 70 dB(A). Se observa que en todos los puntos los valores de Leq(A) sobrepasan en algún momento del día el límite permisible nacional. Los mapas de ruido se realizaron mediante el método Kriging, a través el modelo del semivariograma gaussiano, para todos los días, a excepción del miércoles que se usó el modelo de semivariograma cuadrático racional. Para estos modelos los valores de RMSE e ASE indican una alta calidad de los modelos.

https://doi.org/10.37135/ns.01.13.04

Sofosbuvir más glecaprevir/pibrentasvir como terapia de rescate postrasplante hepático en pacientes con exposición previa a inhibidores de NS5A. Serie de casos
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García-Juárez, Ignacio

; Alonzo-García, Carlos

; Contreras, Alan G.

; Romero-Hernández, Fernanda

; Servín-Rojas, Maximiliano

; Fernández-Ramírez, Alfonso

; Ruiz, Isaac

Gaceta médica de México

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aug 2023, Volume 159 N. 4 Pages 338 - 344

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El tratamiento de la infección crónica por el virus de la hepatitis C (VHC) con antivirales de acción directa logra tasas de respuesta virológica sostenida superiores a 95 %. Sin embargo, el manejo del fracaso virológico sigue siendo un desafío clínico y la evidencia sobre el retratamiento es limitada, especialmente en poblaciones como los receptores de trasplante hepático (TH). Objetivo: Este estudio evaluó el régimen de sofosbuvir más glecaprevir/pibrentasvir (GLE/PIB) en receptores de TH en quienes falló el régimen basado en inhibidores de la proteína no estructural 5A (NS5A). Material y métodos: Estudio retrospectivo de 111 pacientes trasplantados entre enero de 2018 y diciembre de 2020; 18 pacientes presentaron infección recurrente por VHC posterior al TH, tres de ellos tuvieron antecedentes de al menos un régimen basado en inhibidores de NS5A. Se inició terapia de rescate con sofosbuvir más GLE/PIB durante 12 semanas posterior al TH; se registraron las características basales de los pacientes y sus desenlaces. Resultados: En los tres pacientes se logró obtener una carga viral indetectable de VHC a las 12 semanas de finalizar el tratamiento. No se observaron eventos adversos graves. Conclusión: En nuestra serie, sofosbuvir más GLE/PIB durante 12 semanas demostró ser una terapia de rescate efectiva y segura posterior al TH en pacientes previamente tratados con inhibidores de NS5A.

Abstract Background: Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals achieves a sustained virologic response rates higher than 95%. However, virologic failure remains a clinical challenge, and data on retreatment are limited, especially in special populations such as liver transplant (LT) recipients. Objective: This study evaluated the sofosbuvir plus glecaprevir-pibrentasvir (GLE/PIB) regimen in LT recipients who had failed to a nonstructural protein 5A (NS5A) inhibitor-based regimen. Material and methods: Retrospective study of 111 liver transplant recipients between January 2018 and December 2020; 18 patients presented with HCV recurrent infection after LT, out of whom three had a history of at least one NS5A inhibitor-based regimen. Salvage therapy with sofosbuvir plus GLE/PIB was started for 12 weeks; baseline characteristics and outcomes were recorded. Results: All three patients (100%) achieved an undetectable HCV viral load 12 weeks after treatment completion. No serious adverse events were observed. Conclusion: In our series, sofosbuvir plus GLE/PIB for 12 weeks is an effective and safe salvage therapy after LT in patients previously treated with NS5A inhibitors.

https://doi.org/10.24875/gmm.m23000781

Flegmasia cerúlea dolorosa en paciente con trombocitopenia inmune primaria: un gran reto terapéutico
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Álvarez-Perdomo, Luis Carlos

; Romero-Mejía, Edwin Alexis

; Domínguez-Ruiz, Juan Diego

; Velasco-Hoyos, María Fernanda

; Pérez-Covo, Diego Armando

Angiología

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aug 2023, Volume 75 N. 4 Pages 264 - 267

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: la flegmasia cerúlea dolorosa resulta de una trombosis venosa masiva aguda que provoca una obstrucción del drenaje venoso de una extremidad y se asocia con un alto grado de morbilidad. Caso clínico: presentamos el caso de un paciente con flegmasia cerúlea dolorosa y múltiples factores de riesgo para desarrollarla, quien fue llevado a trombólisis dirigida por catéter, con lo que se logró salvar la extremidad. Discusión: la flegmasia cerúlea dolorosa es una entidad poco frecuente que puede progresar de manera rápida y comprometer la vitalidad de la extremidad afectada o llevar a desenlaces fatales, por lo que requiere una pronta sospecha y una intervención emergente. La terapia antitrombótica sigue siendo el manejo de elección.

Abstract Introduction: phlegmasia cerulea dolorosa results from acute massive venous thrombosis that causes obstruction of the venous drainage of an extremity, and it's associated with a high morbidity. Case report: we present the case of a patient with phlegmasia cerulea dolorosa and multiple risk factors for developing it, who was taken to catheter-directed thrombolysis successfully. Discussion: phlegmasia cerulea dolorosathis is a rare entity that can progress rapidly and compromise the vitality of the limb or lead to fatal outcomes, which requires early suspicion and emergency intervention. Antithrombotic therapy continues to be the ideal treatment.

https://doi.org/10.20960/angiologia.00503

Sobrecarga del cuidador de personas en diálisis y el significado de participar en un grupo de apoyo: estudio con metodología mixta
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Cantillo-Medina, Claudia Patricia

; Rodríguez-Vélez, María Elena

; Jiménez-Moreno, Yenny Fernanda

; Perdomo-Romero, Alix Yaneth

; Ramírez-Perdomo, Claudia Andrea

Enfermería Nefrológica

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jun 2023, Volume 26 N. 2 Pages 151 - 157

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: The caregiver of a person on dialysis requires specific interventions aimed at self-care. Support group intervention is a strategy built in collaboration with individuals facing similar issues to share experiences and provide mutual support through planned actions. Objective: To characterize caregivers of individuals on dialysis, understand their burden, and comprehend the meanings constructed through their participation in a support group. Materials and Method: A mixed-methods descriptive study involving 68 caregivers was conducted. The quantitative phase utilized the instrument “Characterization Form of the Non-Communicable Chronic Disease-Patient Caregiver Dyad,” while the qualitative phase employed a hermeneutic phenomenological approach, consisting of 8 in-depth interviews. Results: The majority of caregivers were women, with an average age of 49.4±13.5 years. A high percentage had low socioeconomic status and education levels, with their main occupation being homemaking. Most were married and practiced the Catholic religion, had been providing care for 14 months or more, had no previous caregiving experience, and received some form of support to carry out their tasks. Some degree of burden was identified among them. The analysis of the interviews revealed emerging themes: learning through caregiving, finding understanding and solidarity, supporting each other’s needs, sharing the hardships of caregiving, accompanying each other in spirituality, and reorganizing to continue caregiving. Conclusions: Caregivers live in contexts that increase vulnerability, and for them, the support group provided a space for social support, well-being, accompaniment, and support from nursing care.

RESUMEN Introducción: El cuidador de la persona en diálisis requiere intervenciones específicas orientadas al cuidado de sí mismo. La intervención grupo de apoyo es una estrategia construida conjuntamente con personas que se enfrentan a los mismos problemas para compartir sus experiencias y brindarse apoyo mutuo a través de acciones planificadas. Objetivo: Caracterizar el cuidador de personas en diálisis, su sobrecarga y comprender los significados construidos por su participación en un grupo de apoyo. Materiales y Método: estudio de diseño mixto, descriptivo, participaron 68 cuidadores. La fase cuantitativa se realizó mediante los instrumentos: Ficha de caracterización de la díada persona con Enfermedad Crónica No Transmisible- cuidador familiar y La Escala de sobrecarga de Zarit; y la fase cualitativa con enfoque fenomenológico hermenéutico, se realizaron 8 entrevistas en profundidad. Resultados: La mayoría de cuidadores eran mujeres, con edad promedio de 49,4±13,5 años. Un alto porcentaje con bajo nivel socioeconómico y de escolaridad, su principal ocupación era el hogar. La mayoría estaba casada y profesaba la religión católica, llevaban 14 meses o más cuidando, sin experiencia previa y contaban con algún tipo de apoyo para realizar su tarea. Se identificó en ellos algún grado de sobrecarga. En el análisis de las entrevistas los temas emergentes fueron: aprenderse en el cuidado; encontrarse con comprensión y solidaridad; apoyarse en las necesidades; compartirse la dureza del cuidado; acompañarse en la espiritualidad; reorganizarse para seguir cuidando. Conclusiones: Los cuidadores viven en contextos que aumentan la vulnerabilidad, para ellos el grupo de apoyo fue un espacio de soporte social, fuente de bienestar, acompañamiento y apoyo desde el cuidado enfermero.

https://doi.org/10.37551/s2254-28842023015

Sobrevida do câncer colorretal na Grande Cuiabá, Mato Grosso, Brasil
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Silva, Gustavo Monteiro da

; Souza, Rita Adriana Gomes de

; Lima, Fernanda Cristina da Silva de

; Caló, Romero dos Santos

; Andrade, Amanda Cristina de Souza

; Souza, Bárbara da Silva Nalin de

; Evangelista, Flávio de Macêdo

; Galvão, Noemi Dreyer

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar a sobrevida específica em cinco anos do câncer colorretal diagnosticado entre 2008 e 2013, segundo sexo e faixa etária, de residentes na Grande Cuiabá, Mato Grosso. Métodos: Estudo de coorte retrospectiva. A sobrevida específica pelo câncer colorretal foi considerada como o tempo entre o diagnóstico da doença até o óbito por câncer colorretal, em meses. Utilizaram-se dados do Registro de Câncer de Base Populacional e do Sistema de Informações sobre Mortalidade. Para estimar a probabilidade de sobrevida por sexo e faixa etária, utilizou-se o estimador de Kaplan-Meier, e, para estimar o efeito da faixa etária na sobrevida dos participantes, foi ajustado modelo de Cox estratificado por sexo. Resultados: De 2008 a 2013, registraram-se 683 casos novos e 193 óbitos por câncer colorretal. O tempo mediano entre o diagnóstico e a morte por câncer colorretal foi de 44,8 meses (IC95% 42,4–47,3) para as mulheres e 46,1 meses (IC95% 43,4–48,6) para os homens e a probabilidade de sobrevida em cinco anos de 83,5% (IC95% 79,9–87,2%) e 89,6% (IC95% 86,4–93,0%), respectivamente. Os homens com 70-79 anos (HR=2,97; IC95% 1,11–3,87) e com 80 anos ou mais (HR=3,09; IC95% 1,31–7,27) apresentaram maior risco de mortalidade e sem diferença para as mulheres. Conclusão: O sexo feminino apresentou menor tempo entre o diagnóstico e o óbito pela doença, assim como menor probabilidade de sobrevida. Em contrapartida, foram os homens que apresentaram maior risco de mortalidade a partir dos 70 anos.

ABSTRACT Objective: To analyze the specific five-year survival of colorectal cancer (CRC) diagnosed between 2008 and 2013, according to sex and age group, of residents in Greater Cuiabá, state of Mato Grosso, Brazil. Methods: This is a retrospective cohort study. Specific survival of CRC was considered as the time between disease diagnosis and death from CRC, in months. Data from the Population-Based Cancer Registry and the Brazilian Mortality Information System were used. To estimate the probability of survival by sex and age group, the Kaplan-Meier estimator was used, and to estimate the effect of age group on the survival of participants, the Cox model stratified by sex was adjusted. Results: From 2008 to 2013, 683 new cases and 193 deaths from CRC were registered. The median time between diagnosis and death from CRC was 44.8 months (95%CI 42.4– 47.3) for women and 46.1 months (95%CI 43.4–48.6) for men, and the five-year survival probabilities of 83.5% (95%CI 79.9–87.2%) and 89.6% (95%CI 86.4–93.0%), respectively. Men aged 70–79 years (HR=2.97; 95%CI 1.11–3.87) and 80 years or older (HR=3.09; 95%CI 1.31–7.27) were at higher risk of mortality, and we verified no difference for women. Conclusion: Women had a shorter time between the diagnosis of CRC and death from the disease as well as a lower probability of survival. Conversely, men were at higher risk of mortality after 70 years of age.

https://doi.org/10.1590/1980-549720230022.2

Mindfulness para la reducción de síntomas de estrés, ansiedad y depresión en estudiantes universitarios de Yhú, Paraguay
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Fernández-Romero, Milena

; Rodas-Jara, Ronaldo Luis

; Grance-Sardi, Juan Manuel

; Rodas-Jara, Liza Raquel

; Báez, Diana

; Franco, Fabián

; Franco, Nancy Mabel

; Benite-Aquino, Maria Fernanda

Revista científica ciencias de la salud

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2023, Volume 5 elocation e5115

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Introducción. El estrés, la ansiedad y la depresión son síntomas emergentes en estudiantes universitarios, por esto es vital para controlarlos identificar programas basados en evidencia, de bajo costo, y factibles de ser implementados y replicados en contextos naturales como las universidades. Objetivo. Evaluar el efecto de un taller introductorio a la práctica de mindfulness para la reducción de síntomas del estrés, ansiedad y depresión en estudiantes universitarios de la ciudad de Yhú en el periodo lectivo 2022. Materiales y métodos. Estudio cuasi-experimental en el que participaron en los talleres de mindfulness 20 estudiantes por ocho semanas. La escala estandarizada DASS21 se utilizó para la medición de estrés, la ansiedad y la depresión antes y después de la intervención; y la prueba de rangos con signo de Wilcoxon para muestras pareadas para determinar si había una diferencia en los datos previos y posteriores a la intervención en depresión, ansiedad y estrés. Resultados. Hubo diferencia significativa (p <0.001) en los puntajes pre-post de depresión, ansiedady estrés. Conclusión. Este estudio ha demostrado que las técnicas del mindfulness tienen una efectividad significativa en la reducción de síntomas de ansiedad, estrés y depresión en estudiantes universitarios. Se recomienda seguir evaluando el efecto del mindfulness con estudiantes universitarios, y la utilización de ensayos clínicos más complejos, y considerar además medir la validez social de las intervenciones a través de entrevistas o grupos focales con los participantes.

ABSTRACT Introduction. Stress, anxiety and depression are emerging symptoms in university students; therefore,in order to control them it is vital to identify programs based on evidence, at low cost, and feasible of being implemented and replicated in natural contexts such as universities. Objective. To evaluate the effect of an introductory workshop on the practice of mindfulness for the reduction of symptoms of stress, anxiety and depression in university students from the city of Yhú in the 2022 academic year. Materials and methods. Quasi-experimental study in which 20 students participated in mindfulness workshops for eight weeks. The DASS21 standardized scale was used to measure stress, anxiety and depression before and after the intervention; and the Wilcoxon signed-rank test for paired samples to determine if there was a difference in pre- and post-intervention data on depression, anxiety, and stress. Results. There was a significant difference (p < 0.001) in the pre-post scores of depression, anxiety and stress. Conclusion. This study has shown that mindfulness techniques are significantly effective in reducing symptoms of anxiety, stress, and depression in university students. It is recommended to continue evaluating the effect of mindfulness with university students, and the use of more complex clinical trials, and also consider measuring the social validity of the interventions through interviews or focus groups with the participants.

https://doi.org/10.53732/rccsalud/2023.e5115

Experiencias de docentes y estudiantes en la educación remota de emergencia: oportunidades para mejorar la educación del pregrado en medicina
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Vives-Varela, Tania

; Limón-Rojas, Ana E

; Wakida-Kuzunoki, Guillermo H

; Orea-Antonio, Fabiola

; Leyva-Mondragón, M Fernanda

; Rojas-Hernández, M Teresa

; Romero-Romero, Enrique

; Aragón-Robles, Javier

; Morales-Luna, Pamela

; Fortoul, Teresa I

FEM: Revista de la Fundación Educación Médica

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2023, Volume 26 N. 4 Pages 151 - 158

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Introducción. Los ciclos clínicos de pregrado representan los escenarios principales en los que los estudiantes de medicina consolidan los conocimientos. Sin embargo, a principios de 2020, la mayoría de los estudiantes fue confinada en sus domicilios debido a la pandemia por el SARS-CoV-2. Los procesos formativos continuaron desde los hogares por medio de la educación remota de emergencia, una modalidad de enseñanza basada en el uso intensivo de la tecnología que, a pesar de hacerse de manera improvisada, respondió a la situación educativa de urgencia. El propósito de este estudio fue indagar la experiencia educativa de estudiantes y docentes que se encontraban en los años clínicos de pregrado de la carrera de medicina con el fin de identificar las oportunidades de mejora en la enseñanza a partir de la crisis sanitaria vivida. Sujetos y métodos. Se realizó un estudio cualitativo de carácter descriptivo con la técnica de grupos focales. El análisis se basó en la reducción de datos, en la triangulación entre estamentos y en la bibliografía del tema. Resultados. Se realizaron 16 grupos focales con un total de 148 participantes. Se identificaron cuatro categorías generales: a) enseñanza y aprendizaje; b) evaluación de la práctica clínica; c) identidad profesional, y d) sugerencias en busca de mejoras en la formación de los médicos. Conclusiones. Las reflexiones reconocen la necesidad de incorporar las tecnologías digitales de una manera planeada y diseñada en conjunto por expertos y docentes para adaptarlas a las necesidades de los contextos educativos, y continuar con modelos híbridos o combinados para mejorar la educación médica.

Introduction. During medical education, undergraduate clinical cycles represent the main scenarios where students consolidate knowledge. However, in the early 2020s, most students were confined to their homes due to the SARS-Cov-2 pandemic. In this situation, the digital network allowed the educational processes to continue from their homes through remote emergency education (REE), a teaching modality based on the intensive use of technology that, despite having been improvised, responded to the emergency educational situation. Therefore, this study aimed to investigate the educational experience of students and teachers in the undergraduate clinical years of the medical degree in order to identify opportunities for improvement in teaching after the health crisis. Subjects and methods. A descriptive qualitative study was carried out with a phenomenological approach through the focus group technique. The qualitative analysis was based on data reduction and triangulation between strata and subject literature. Results. Sixteen focus groups were integrated with a total of 148 participants. Four categories were identified: a) teaching and learning; b) evaluation of clinical practice; c) professional identity, and d) suggestions for improvement in the training of physicians. Conclusions. The reflections lead to recognizing the need to incorporate digital technology designed by experts and teachers to adapt them to the real needs of the educational contexts and to continue with a hybrid or combined model that supports the improvement of medical education.

https://doi.org/10.33588/fem.264.1290

Sobrevida do câncer colorretal na Grande Cuiabá, Mato Grosso, Brasil
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Silva, Gustavo Monteiro da

; Souza, Rita Adriana Gomes de

; Lima, Fernanda Cristina da Silva de

; Caló, Romero dos Santos

; Andrade, Amanda Cristina de Souza

; Souza, Bárbara da Silva Nalin de

; Evangelista, Flávio de Macêdo

; Galvão, Noemi Dreyer

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720230022.2

Antifibrotic therapy in idiopathic pulmonary fibrosis candidates for lung transplantation undergoing pulmonary rehabilitation
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Pereira, Monica Pruss

; Branchini, Gisele

; Nunes, Fernanda Bordignon

; Altmayer, Stephan

; Hetzel, Guilherme Moreira

; Romero, Iveth

; Rubin, Adalberto Sperb

; Florian, Juliessa

; Nascimento, Douglas Zaione

; Watte, Guilherme

Jornal Brasileiro de Pneumologia

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2023, Volume 49 N. 1 elocation e20220250

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To investigate the impact of pulmonary rehabilitation (PR) on functional outcomes and health-related quality of life (HRQoL) in idiopathic pulmonary fibrosis (IPF) patients placed on a lung transplant waitlist and receiving antifibrotic therapy (AFT). Methods: This was a retrospective observational study of consecutive IPF patients receiving AFT with either pirfenidone or nintedanib (the AFT group) and undergoing PR between January of 2018 and March of 2020. The AFT group and the control group (i.e., IPF patients not receiving AFT) participated in a 12-week PR program consisting of 36 sessions. After having completed the program, the study participants were evaluated for the six-minute walk distance (6MWD) and HRQoL. Pre- and post-PR 6MWD and HRQoL were compared within groups and between groups. Results: There was no significant difference between the AFT and control groups regarding baseline characteristics, including age, airflow limitation, comorbidities, and oxygen requirement. The AFT group had a significant increase in the 6MWD after 12 weeks of PR (effect size, 0.77; p < 0.05), this increase being significant in the between-group comparison as well (effect size, 0.55; p < 0.05). The AFT group showed a significant improvement in the physical component of HRQoL at 12 weeks (effect size, 0.30; p < 0.05). Conclusions: Among IPF patients undergoing PR, those receiving AFT appear to have greater improvements in the 6MWD and the physical component of HRQoL than do those not receiving AFT.

RESUMO Objetivo: Investigar o impacto da reabilitação pulmonar (RP) em desfechos funcionais e na qualidade de vida relacionada à saúde (QVRS) em pacientes com fibrose pulmonar idiopática (FPI) em lista de espera para transplante de pulmão e em tratamento com antifibróticos (AF). Métodos: Estudo observacional retrospectivo com pacientes consecutivos com FPI em tratamento com pirfenidona ou nintedanibe (grupo AF) submetidos a RP entre janeiro de 2018 e março de 2020. O grupo AF e o grupo controle (pacientes com FPI que não estavam em tratamento com AF) participaram de um programa de RP com 36 sessões ao longo de 12 semanas. Após o término do programa, os participantes foram avaliados quanto à distância percorrida no teste de caminhada de seis minutos (DTC6) e à QVRS. A DTC6 e a QVRS pré e pós-RP foram comparadas intra e intergrupos. Resultados: Não houve diferença significativa entre os grupos AF e controle quanto às características basais, incluindo idade, limitação do fluxo aéreo, comorbidades e necessidade de oxigênio. O grupo AF apresentou um aumento significativo da DTC6 após 12 semanas de RP (tamanho do efeito: 0,77; p < 0,05); esse aumento também foi significativo na comparação intergrupos (tamanho do efeito: 0,55; p < 0,05). O grupo AF apresentou melhora significativa no componente físico da QVRS após 12 semanas (tamanho do efeito: 0,30; p < 0,05). Conclusões: Em pacientes com FPI submetidos a RP, a melhora na DTC6 e no componente físico da QVRS parece ser maior naqueles que estejam recebendo tratamento com AF do que naqueles que não o estejam.

https://doi.org/10.36416/1806-3756/e20220250

10.

Bases sociocognitivas do discurso de ódio online no Brasil: uma revisão narrativa interdisciplinar Brasil
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Freitas, Ana Luísa

; Romero, Ruth Lyra

; Pantaleão, Fernanda Naomi

; Boggio, Paulo Sérgio

Texto Livre

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2023, Volume 16 elocation e46002

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O crescimento das redes sociais deu força sem precedentes aos discursos de ódio, que têm causado danos globalmente. Este artigo objetivou discutir os substratos sociocognitivos do discurso de ódio e o papel das redes sociais no agravamento do problema, integrando conhecimentos das neurociências, da Psicologia Social, Análise Crítica do Discurso, entre outras, propondo uma breve revisão narrativa para auxiliar a compreensão e o combate ao discurso de ódio no contexto brasileiro. Por meio da articulação dessas áreas, foram abordados temas centrais ao discurso de ódio: sua natureza como prática social e os processos sociocognitivos subjacentes a ele, como a categorização social e formação de estereótipos, preconceitos e identidade social, fenômenos que podem mediar conflitos interpessoais e intergrupais. A partir de conceitos já bastante consolidados, buscou-se literatura atualizada para compreender e ilustrar a dimensão da problemática dos discursos de ódio. Este trabalho aponta direções estratégicas para combater e mitigar efeitos negativos dos discursos de ódio, para promover sociedades mais justas e cooperativas, com adoção de medidas socioeducativas dentro e fora da Internet. globalmente problema neurociências Social Discurso outras brasileiro áreas ele estereótipos intergrupais consolidados buscouse buscou se cooperativas Internet

Abstract The growth of social networks has given unprecedented strength to hate speech, which has caused damage globally. This article aimed to discuss the sociocognitive substrates of hate speech and the role of social networks in exacerbating the problem by integrating knowledge from neurosciences, Social Psychology, Critical Discourse Analysis, among others and proposing a brief narrative review to aid understanding and combat hate speech in the Brazilian context. Through the articulation of these areas, central themes were addressed to hate speech: its nature as a social practice and the sociocognitive processes underlying it, such as social categorization and the formation of stereotypes, prejudices, and social identity, phenomena that can mediate interpersonal and intergroup conflicts. From already well-established concepts, up-to-date literature was sought to understand and illustrate the dimension of the problem of hate speech. This work points out strategic directions to combat and mitigate the negative effects of hate speech, to promote more just and cooperative societies, with the adoption of socio-educational measures both on and off the Internet. globally neurosciences Psychology Analysis context areas it stereotypes prejudices identity conflicts wellestablished well established concepts uptodate up date societies socioeducational socio educational Internet

https://doi.org/10.1590/1983-3652.2023.46002

11.

Posicionamento sobre a Saúde Cardiovascular nas Mulheres – 2022
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Oliveira, Glaucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Marques-Santos, Celi

; Costa, Maria Elizabeth Navegantes Caetano

; Carvalho, Regina Coeli Marques de

; Freire, Cláudia Maria Vilas

; Magalhães, Lucelia Batista Neves Cunha

; Hajjar, Ludhmila Abrahão

; Rivera, Maria Alayde Mendonça

; Castro, Marildes Luiza de

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Lantieri, Carla Janice Baister

; Polanczyk, Carisi Anne

; Albuquerque, Carlos Japhet da Matta

; Born, Daniel

; Falcheto, Eduardo Belisário

; Bragança, Érika Olivier Vilela

; Braga, Fabiana Goulart Marcondes

; Colombo, Fernanda M. Consolim

; Jatene, Ieda Biscegli

; Costa, Isabela Bispo Santos da Silva

; Rivera, Ivan Romero

; Scholz, Jaqueline Ribeiro

; Melo Filho, José Xavier de

; Santos, Magaly Arrais dos

; Izar, Maria Cristina de Oliveira

; Azevedo, Maria Fátima

; Moura, Maria Sanali

; Campos, Milena dos Santos Barros

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rizk, Stéphanie Itala

; Rodrigues, Thais de Carvalho Vieira

; Salim, Thaís Rocha

; Lemke, Viviana de Mello Guzzo

Arquivos Brasileiros de Cardiologia

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nov 2022, Volume 119 N. 5 Pages 815 - 882

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220734

12.

Behavior of the Genetic Markers at Screening during the First Trimester of Pregnancy in Euploid Fetuses
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Romero Infante, Ximena Carolina

; Uriel, Montserrat

; Gutiérrez, Alejandra

; Hernández, María Fernanda

; Hernández, Andres Felipe

; Jiménez, Laura Catalina

; Malagón-Rojas, Jeadran Nevardo

; Rincón Franco, Sara

Revista Brasileira de Ginecologia e Obstetrícia

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jul 2022, Volume 44 N. 7 Pages 646 - 653

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Este estudo tem como objetivo descrever o comportamento do rastreamento de cromossomopatias em fetos euploides. Métodos Trata-se de um estudo prospectivo descritivo com 566 pacientes, entre 11 e 14 semanas de gestação. A associação entre a ultrassonografia e as variáveis sorológicas foi estudada. Para as variáveis quantitativas foi utilizado o teste de Spearman; para as qualitativas com variáveis quantitativas foi utilizado o teste U de Mann-Whitney e para as variáveis qualitativas foi aplicado o teste X2. A significância foi fixada em p ≤ 0,05. Resultados Constatou-se que a idade gestacional tem correlação com o ducto venoso, translucência nucal, fração livre da subunidade β da gonadotrofina coriônica humana, proteína plasmática A associada à gravidez e fator de crescimento placentário; há também correlação entre a história de abortos e o osso nasal. Além disso, correlacionamos o índice de massa corporal com translucência nucal, fração livre da subunidade β da gonadotrofina coriônica humana e proteína plasmática A associada à gravidez. A idade materna foi relacionada com fração livre da subunidade β da gonadotrofina coriônica humana e proteína plasmática A associada à gravidez. Conclusão Nosso estudo demonstra pela primeira vez o comportamento dos marcadores bioquímicos e ultrassonográficos de triagem de cromossomas durante o primeiro trimestre em fetos euploides na Colômbia. Nossa informação é consistente com a referência de valores internacionais. Além disso, mostram-se as relações das diferentes variáveis com as características maternas para determinar as variáveis capazes de ajudar no desenvolvimento de um processo de rastreamento durante o primeiro trimestre com alta taxa de detecção.

Abstract Objective This study aims to describe the behavior of chromosomopathy screenings in euploid fetuses. Methods This is a prospective descriptive study with 566 patients at 11 to 14 weeks of gestation. The associations between ultrasound scans and serological variables were studied. For the quantitative variables we used the Spearman test; for the qualitative with quantitative variables the of Mann-Whitney U-test; and for qualitative variables, the X2 test was applied. Significance was set at p ≤ 0.05. Results We have found that gestational age has correlation with ductus venosus, nuchal translucency, free fraction of β subunit of human chorionic gonadotropin, pregnancy-associated plasma protein-A and placental growth factor; there is also a correlation between history of miscarriages and nasal bone. Furthermore, we correlated body mass index with nuchal translucency, free fraction of β subunit of human chorionic gonadotropin, and pregnancy-associated plasma protein-A. Maternal age was associated with free fraction of β subunit of human chorionic gonadotropin and pregnancy-associated plasma protein-A. Conclusion Our study demonstrates for the first time the behavior of the biochemical and ultrasonographic markers of chromosomopathy screenings during the first trimester in euploid fetuses in Colombia. Our information is consistent with international reference values. Moreover, we have shown the correlation of different variables with maternal characteristics to determine the variables that could help with development of a screening process during the first trimester with high detection rates.

https://doi.org/10.1055/s-0042-1744461

13.

La concepción del trabajo en horarios atípicos: una démarche de innovación social realizada en entorno hospitalario
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Cheyrouze, Marlène

; Romero, Fernanda

Laboreal

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jun 2022, Volume 18 N. 1 elocation e19320

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.4000/laboreal.19320

14.

Control scheme selection and optimal tuning in industrial process control using factorial experiment design
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Acosta-Villamil, David Roberto

; Noguera-Polania, José Fernando

; Verdeza-Villalobos, Arnaldo

; Foliaco-Romero, Blanca Luz

; Rincón-Montenegro, Adriana Fernanda

; Sanjuan-Mejía, Marco Enrique

Revista Facultad de Ingeniería Universidad de Antioquia

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jun 2022, N. 103 Pages 34 - 43

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN En este estudio se presenta un nuevo enfoque experimental para la selección óptima de una estrategia de control basada en el actuador. El enfoque propuesto es un método de dos etapas: primero se aplica un diseño de experimento factorial de dos niveles con n factores (2n) para comparar diferentes esquemas de control. La comparación de esquemas se lleva a cabo en términos de consumo de energía y rendimiento de circuito cerrado. Para el mejor esquema relativo, se completa un Diseño Central Compuesto Centrado en las Caras (CCF, por sus siglas en inglés) obteniendo parámetros de controlador que optimizan el rendimiento, en términos del Error absoluto integral (IAE, por sus siglas en inglés), mientras operan en una región de bajo consumo de energía. El enfoque propuesto se probó experimentalmente utilizando datos reales obtenidos de una planta prototipo de laboratorio. Algunas pruebas experimentales que ilustran la idoneidad de nuestro método se muestran al final de este artículo.

ABSTRACT In this study, a novel experimental approach for the optimal selection of an actuator-based control strategy is presented. The proposed approach is a two-stage method: first, a two-level factorial experiment design with n factors (2n) was applied to compare different control schemes. Schemes comparison was carried out in terms of energy consumption and closed-loop performance. For the best relative scheme, a Central Composite Face-centered (CCF) design was completed obtaining the controller parameters that optimize the performance in terms of the Integral Absolute Error (IAE) while operating in a region of low energy consumption. The proposed approach was experimentally tested using real data obtained from a laboratory prototype plant. Some experimental tests illustrating the suitability of our method are shown at the end of this article.

https://doi.org/10.17533/udea.redin.20201010 49 downloads

15.

Caracterización de creencias e imaginarios de estudiantes universitarios sobre la evaluación en matemáticas
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Penagos, Mauricio

; Osorio-Amaya, Elkin Alejandro

; Morales-Romero, Lina Fernanda

Revista de Investigación, Desarrollo e Innovación

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jun 2022, Volume 12 N. 1 Pages 87 - 96

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen En este artículo se presenta la caracterización de las creencias e imaginarios construidas por los estudiantes universitarios del programa de Licenciatura en Matemáticas sobre la evaluación. Esto se realiza con base en el análisis cualitativo sistemático del discurso de los sujetos, el cual se obtuvo por medio de dos entrevistas y dos encuestas realizadas a lo largo de un semestre académico. Las creencias se categorizaron en tres grupos: la cuantificación de saberes, la comunicación del docente y la didáctica de la evaluación. Además, se hizo tangible el imaginario que construyen los estudiantes sobre este proceso por medio de una representación gráfica, generada a partir del análisis sistemático desarrollado. Para los estudiantes este proceso está integrado en su formación, se presenta de forma clara y concisa, utilizado para cuantificar su desempeño a la vez que realimenta su desarrollo, que carece de características didácticas y que representa retos, angustias, incertidumbres y confusiones.

Abstract This article shows the characterization of the beliefs and imaginaries built by the university students of the B. Sc. in Mathematics teaching training program about evaluation. This is done based on the systematic qualitative analysis of the subjects' discourse, which was obtained through two interviews and two surveys carried out throughout an academic semester. The beliefs were categorized into three groups: the quantification of knowledge, the communication of the teacher and the didactics of the evaluation. In addition, the imaginary that students build about this process became tangible through a graphic representation generated from the systematic analysis developed. For students, this process is integrated into their educational process, it is presented in a clear and concise way, used to quantify their performance while feeding back their development, which lacks didactic characteristics and represents challenges, anxieties, uncertainties and confusion.

https://doi.org/10.19053/20278306.v12.n1.2022.14210

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