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Feitosa, Audes Diógenes de Magalhães Barroso, Weimar Kunz Sebba Mion Júnior, Décio Nobre, Fernando Mota-Gomes, Marco Antonio Jardim, Paulo Cesar Brandão Veiga Amodeo, Celso Camargo, Adriana Alessi, Alexandre Sousa, Ana Luiza Lima Brandão, Andréa Araujo Pio-Abreu, Andrea Sposito, Andrei Carvalho Pierin, Angela Maria Geraldo Paiva, Annelise Machado Gomes de Spinelli, Antonio Carlos de Souza Machado, Carlos Alberto Poli-de-Figueiredo, Carlos Eduardo Rodrigues, Cibele Isaac Saad Forjaz, Cláudia Lúcia de Moraes Sampaio, Diogo Pereira Santos Barbosa, Eduardo Costa Duarte Freitas, Elizabete Viana de Cestário , Elizabeth do Espírito Santo Muxfeldt, Elizabeth Silaid Lima Júnior, Emilton Campana, Erika Maria Gonçalves Feitosa, Fabiana Gomes Aragão Magalhães Consolim-Colombo, Fernanda Marciano Almeida, Fernando Antônio de Silva, Giovanio Vieira da Moreno Júnior, Heitor Finimundi, Helius Carlos Guimarães, Isabel Cristina Britto Gemelli, João Roberto Barreto Filho, José Augusto Soares Vilela-Martin, José Fernando Ribeiro, José Marcio Yugar-Toledo, Juan Carlos Magalhães, Lucélia Batista Neves Cunha Drager, Luciano Ferreira Bortolotto, Luiz Aparecido Alves, Marco Antonio de Melo Malachias, Marcus Vinícius Bolívar Neves, Mario Fritsch Toros Santos, Mayara Cedrim Dinamarco, Nelson Moreira Filho, Osni Passarelli Júnior, Oswaldo Valverde de Oliveira Vitorino, Priscila Valverde de Oliveira Miranda, Roberto Dischinger Bezerra, Rodrigo Pedrosa, Rodrigo Pinto Paula, Rogério Baumgratz de Okawa, Rogério Toshiro Passos Póvoa, Rui Manuel dos Santos Fuchs, Sandra C. Inuzuka, Sayuri Ferreira-Filho, Sebastião R. Paffer Fillho, Silvio Hock de Jardim, Thiago de Souza Veiga Guimarães Neto, Vanildo da Silva Koch, Vera Hermina Gusmão, Waléria Dantas Pereira Oigman, Wille Nadruz, Wilson

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Fecha de publicación: 2023-09-23

Resumen: En Es Pt

Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population. Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care. It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations. Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced. Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM). Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance. Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.

La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial. La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización. Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones. Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA. La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA). Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia. Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.

A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial. A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização. Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações. Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA. A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA). Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz). Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento.

https://doi.org/10.1590/SciELOPreprints.7057

Analysis of the Influence Of Friction Stir Welding on the Microstructure and Mechanical Properties of Alloy UNS-C27200 (CU-ZN)
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Rosa, Renato F.

; Almeida, Italo O.

; Varasquim, Francisco M. F. A.

; Junior, Eli J. C.

; Couto, Antônio A.

; Santos, Vinicius T.

; Silva, Márcio R.

; Nakamoto, Francisco Y.

; Santos, Givanildo A.

Materials Research

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2023, Volumen 26 Supl. 1 elocation e20220581

Resumen: En | Texto: En | PDF: En

The copper alloy UNS-C27200 is a binary brass, composed of 38wt%Zn, beeing one of the most used in the industry. The union of Cu-Zn alloys by conventional welding by fusion in thin plates presents several challenges. The Friction Stir Welding (FSW) process performs the union of two, or more materials, through a rotating tool that travels throughout the welding region. One the great advantages of FSW is working below the melting point of the material, which reduces the change in the microstructure and properties of the material, when compared to conventional welding processes. Due to the lack of research on FSW process in lap brass joints with thin thicknesses, the present work aims to expand these studies in order to contribute to future research. Eight conditions were evaluated, varying rotation and welding speed. In the best results by visual inspection, analyzes of microstructure, temperature, microhardness and mechanical strength were performed. The better welding results were obtained with ω=1050 rpm and ν=20 mm/min. There was reduction of approximately 50% between Stir Zone and Base metal. The mechanical strength was affected by the pin hole resulting from the process. The microstructure revealed a homogeneous mixture in the stir zone and no defects were detected.

https://doi.org/10.1590/1980-5373-mr-2022-0581

Chronic inflammatory diseases, subclinical atherosclerosis, and cardiovascular diseases: Design, objectives, and baseline characteristics of a prospective case-cohort study ‒ ELSA-Brasil
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Bensenor, Isabela M.

; Goulart, Alessandra C.

; Pereira, Alexandre C.

; Brunoni, André R.

; Alencar, Airlane

; Santos, Raul D.

; Bittencourt, Márcio S.

; Telles, Rosa W.

; Machado, Luciana Andrade Carneiro

; Barreto, Sandhi Maria

; de Almeida-Pititto, Bianca

; Janovsky, Carolina Porto Silva

; Sgarbi, José Augusto

; Tebar, William R.

; Meneghini, Vandrize

; Barbosa Junior, Fernando

; Ribeiro, Ana Cristina de Medeiros

; Pasoto, Sandra Gofinet

; Pereira, Rosa Maria R.

; Bonfá, Eloísa

; Sipahi, Aytan M.

; Santos, Itamar de S.

; Lotufo, Paulo A.

Clinics

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2022, Volumen 77 elocation 100013

Resumen: En | Texto: En | PDF: En

Abstract Objectives This analysis describes the protocol of a study with a case-cohort to design to prospectively evaluate the incidence of subclinical atherosclerosis and Cardiovascular Disease (CVD) in Chronic Inflammatory Disease (CID) participants compared to non-diseased ones. Methods A high-risk group for CID was defined based on data collected in all visits on self-reported medical diagnosis, use of medicines, and levels of high-sensitivity C-Reactive Protein >10 mg/L. The comparison group is the Aleatory Cohort Sample (ACS): a group with 10% of participants selected at baseline who represent the entire cohort. In both groups, specific biomarkers for DIC, markers of subclinical atherosclerosis, and CVD morbimortality will be tested using weighted Cox. Results The high-risk group (n = 2,949; aged 53.6 ± 9.2; 65.5% women) and the ACS (n=1543; 52.2±8.8; 54.1% women) were identified. Beyond being older and mostly women, participants in the high-risk group present low average income (29.1% vs. 24.8%, p < 0.0001), higher BMI (Kg/m2) (28.1 vs. 26.9, p < 0.0001), higher waist circumference (cm) (93.3 vs. 91, p < 0.0001), higher frequencies of hypertension (40.2% vs. 34.5%, p < 0.0001), diabetes (20.7% vs. 17%, p = 0.003) depression (5.8% vs. 3.9%, p = 0.007) and higher levels of GlycA a new inflammatory marker (p < 0.0001) compared to the ACS. Conclusions The high-risk group selected mostly women, older, lower-income/education, higher BMI, waist circumference, and of hypertension, diabetes, depression, and higher levels of GlycA when compared to the ACS. The strategy chosen to define the high-risk group seems adequate given that multiple sociodemographic and clinical characteristics are compatible with CID.

https://doi.org/10.1016/j.clinsp.2022.100013

Schools reopening and the COVID-19 pandemic: a case study from Macaé, Rio de Janeiro, Brazil
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POZZOBON, ALLAN P. B.

; PETRY, ANA C.

; ZILBERBERG, CARLA

; BARROS, CINTIA M. DE

; NEPOMUCENO-SILVA, JOSÉ L.

; FEITOSA, NATÁLIA M.

; GOMES NETO, LUPIS R.

; RODRIGUES, BRUNO C.

; BRINDEIRO, RODRIGO M.

; NOCCHI, KEITY JAQUELINE C.V.

; MURY, FLAVIA B.

; SOUZA-MENEZES, JACKSON DE

; SILVA, MANUELA L. DA

; MEDEIROS, MARCIO JOSÉ DE

; GESTINARI, RAQUEL S.

; ALVARENGA, ALESSANDRA S. DE

; SILVA, CARINA A.O.

; SANTOS, DANIELE G. DOS

; SILVESTRE, DIEGO HENRIQUE

; SOUSA, GRAZIELE F. DE

; ALMEIDA, JANIMAYRI F. DE

; SILVA, JHENIFER N. DA

; BRANDÃO, LAYZA M.

; DRUMMOND, LEANDRO O.

; CARPES, RAPHAEL M.

; SANTOS, RENATA C. DOS

; PORTAL, TAYNAN M.

; TANURI, AMILCAR

; NUNES-DA-FONSECA, RODRIGO

Anais da Academia Brasileira de Ciências

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2022, Volumen 94 elocation e20211361

Resumen: En | Texto: En | PDF: En

Abstract Since the first reported case of COVID-19 in Brazil, the public and private educational system started to close. Up to November 2020, scientific discussions about the return of schooling activities have been rarely performed by the national scientific community and police-makers. The great delay of school returning in Brazil contrasts with successful international strategies of school reopening worldwide and seems counterintuitive with the reopening of non-essential activities. Here, important issues to be considered before and during school reopening are reviewed and discussed. COVID-19 testing is essential to avoid disease spreading, but high cost of individual RT-qPCRs impairs an extensive testing strategy for school returning. To reduce costs and increase the speed of diagnosis, we tested the efficiency of a pooled-sample PCR strategy in a cohort of the educational staff in the city of Macaé/RJ, finding five asymptomatic individuals (0,66%) among the 754 people tested. Thus, a polled-sample PCR testing strategy of the educational staff might prevent infection spreading in schools at a reasonable cost. We discuss how our test strategy could be coupled with internationally recognized safety rules to allow for a safe school return and how countries from different world regions are dealing with educational activities during COVID-19 pandemic.

https://doi.org/10.1590/0001-3765202220211361

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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Mar 2021, Volumen 116 Nº 3 Paginas 516 - 658

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 descargas

Assessing the undrained strength of very soft clays in the SPT
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Lopes, Francisco R.

; Oliveira, Osvangivaldo C.

; Almeida, Marcio S. S.

Soils and Rocks

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2021, Volumen 44 Nº 4 elocation e2021060520

Resumen: En | Texto: En | PDF: En

Abstract The log of a SPT in very soft clay may simply indicate a zero blow-count, or present information on the penetration – under self-weight – of the composition (sampler, rods and hammer) as recommended by some standards. The second type of information is often disregarded by design engineers due to the lack of a standard procedure for measuring these penetrations or because the test is regarded as not sensitive enough to give an indication on the undrained shear strength of soft clays. The penetration under the composition’s self-weight, however, can indicate the magnitude of Su, which, along with other more specific and sensitive tests, can help in assessing the spatial distribution of clay consistency in a large deposit. A proposed test procedure and interpretation had been given in an earlier technical note. This note presents an extended formulation and an evaluation of Su via the SPT at a construction site in Rio de Janeiro, including comparisons with results of piezocone and vane tests. The values of Su obtained with the SPT lie between the profiles given by vane tests, corrected by Plasticity Index, and the Critical State Theory, the latter representing a lower bound to the clay strength.

https://doi.org/10.28927/sr.2021.060520 14 descargas

New Magnetic Fe Oxide-Carbon Based Acid Catalyst Prepared from Bio-Oil for Esterification Reactions
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Ballotin, Fabiane C.

; Almeida, Vitor F.

; Ardisson, José D.

; Silva, Márcio J. da

; Soares, Ricardo R.

; Teixeira, Ana Paula C.

; Lago, Rochel M.

Journal of the Brazilian Chemical Society

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Ago 2020, Volumen 31 Nº 8 Paginas 1714 - 1724

Resumen: En | Texto: En | PDF: En

In this work, bio-oil (an organic matrix rich in oxygen functionalities) was used to efficiently dissolve and disperse Fe3+ which upon thermal treatment produced a carbon containing dispersed and encapsulated Fe oxide magnetic nanoparticles. These materials were prepared by dissolution of 8, 16 and 24 wt.% Fe3+ salt in bio-oil followed by treatment at 400, 450, 500 or 600 ºC in N2 atmosphere. X-ray diffraction (XRD), scanning (SEM) and transmission electron microscopies (TEM), elemental analysis, thermogravimetric-mass spectrometry (TG-MS), potentiometric titration, Raman and Mössbauer spectroscopies showed that Fe3+ species in bio-oil is reduced to produce magnetic nanoparticles phases: magnetite Fe3O4 and maghemite γ-Fe2O3. At low temperatures, the iron phases were less protected, and the carbon matrix was more reactive, while in temperatures above 500 ºC, the iron phases were more stable, however, the carbon matrix was less reactive. Reaction of these magnetic carbon materials with concentrated H2SO4 produced surface sulfonic acidic sites (ca. 1 mmol g-1), especially for the materials obtained at 400 and 450 ºC. The materials were used as catalysts on esterification reaction of oleic acid with methanol at 100 ºC and conversions of 90% were reached, however, after 2 consecutive uses, the conversion decreased to 30%, being required more studies to improve the material stability.

https://doi.org/10.21577/0103-5053.20200057 263 descargas

Biomechanics of extra-alveolar mini-implants
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Almeida, Marcio R.

Dental Press Journal of Orthodontics

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Ago 2019, Volumen 24 Nº 4 Paginas 93 - 109

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO É inegável que a ancoragem com mini-implantes extra-alveolares revolucionou a nossa especialidade. No mesmo sentido, o correto entendimento da biomecânica com mini-implantes permitiu ampliar a gama de movimentos dentários como nunca visto na prática clínica. Deve-se, porém, atentar às diversas possibilidades dos sistemas de aplicação das forças decorrentes do uso da ancoragem esquelética, com vistas a produzir tratamentos cada vez mais eficientes, principalmente em relação aos efeitos no plano oclusal. Assim, o presente artigo versa, por meio de casos clínicos, sobre a aplicação de conceitos da biomecânica que são extremamente relevantes para o correto emprego dos mini-implantes extra-alveolares.

ABSTRACT It is undeniable that extra-alveolar mini-implants anchorage has revolutionized Orthodontics. Correspondingly, the proper understanding of mini-implants biomechanics allowed to broaden the range of dental movements as never seen before in clinical practice. However, in order to produce better treatments, especially regarding the effects in occlusal plane, it is important to be aware of the numerous possibilities of applying force systems based on skeletal anchorage. Thus, this paper aims to address, by means of clinical cases, the application of biomechanics concepts that are extremely relevant to the proper employment of extra-alveolar mini-implants.

https://doi.org/10.1590/2177-6709.24.4.093-109.sar 8756 descargas

10.

Osteogenesis imperfecta in Brazilian patients
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Trancozo, Maira

; Moraes, Marcos V.D.

; Silva, Dalila A.

; Soares, Jéssica A.M.

; Barbirato, Clara

; Almeida, Márcio G.

; Santos, Lígia R.

; Rebouças, Maria R. G. O.

; Akel Jr, Akel N.

; Sipolatti, Valentim

; Nunes, Vanda R. R.

; Errera, Flavia I. V.

; Aguena, Meire

; Passos-Bueno, Maria R.

; Paula, Flavia de

Genetics and Molecular Biology

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Jun 2019, Volumen 42 Nº 2 Paginas 344 - 350

Resumen: En | Texto: En | PDF: En

Abstract Osteogenesis Imperfecta (OI) is a heterogeneous genetic disorder characterized by bone fragility and fracture. Mutations in 20 distinct genes can cause OI, and therefore, the genetic diagnosis of OI is frequently difficult to obtain because of the great number of genes that can be related with this disease. Studies that report the most frequently mutated genes in OI patients can help to improve molecular strategies for diagnosis of the disease. In order to characterize the mutation profile of OI in Brazilian patients, we analyzed 30 unrelated patients through SSCP screening, NGS gene panel, and/or Sanger sequencing for the 11 most frequently mutated genes in the database of mutations, including COL1A1, COL1A2, P3H1, CRTAP, PPIB, SERPINH1, SERPINF1, FKBP10, SP7, WNT1 and IFITM5. Disease-causing variants were identified in COL1A1, COL1A2, FKBP10, P3H1, and IFITM5. A total of 28 distinct mutations were identified, including seven novel changes. Our data show that the analysis of these five genes is able to detect at least 95% of causative mutations in OI disorder from Brazilian population. However, it has to be taken into considerations that distinct populations can have different frequencies of disease-causing variants. Hence, it is important to replicate this study in other groups.

https://doi.org/10.1590/1678-4685-gmb-2018-0043 1276 descargas

11.

A Fast, Low-Cost, and Environmental Friendly Micro-Flow-Batch Analyzer for Photometric Determination of Sulfites in Beverages
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Tavares, Márcio R. S.

; Andrade, Stéfani I. E.

; Lima, Marcelo B.

; Barreto, Inakã S.

; Araújo, Mário C. U. de

; Almeida, Luciano F.

Journal of the Brazilian Chemical Society

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May 2019, Volumen 30 Nº 5 Paginas 1089 - 1094

Resumen: En | Texto: En | PDF: En

An automated microsystem for sulfite determination in beverages was developed. It presents higher sampling throughput, lower chemical consumption and less waste generation than previous flow methods, while using the same p-rosaniline-formaldehyde-sulfite reaction. The sampling rate, limit of detection (LOD), and relative standard deviation (RSD) were estimated at 130 h-1, 80.0 µg L–1, and < 1.3% (n = 5), respectively. Recoveries ranged from 96.8 to 102.6%.

https://doi.org/10.21577/0103-5053.20180243 458 descargas

12.

High-resolution topography for Digital Terrain Model (DTM) in Keller Peninsula, Maritime Antarctica
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SCHÜNEMANN, ADRIANO L.

; ALMEIDA, PEDRO HENRIQUE A.

; THOMAZINI, ANDRÉ

; FERNANDES FILHO, ELPÍDIO I.

; FRANCELINO, MÁRCIO R.

; SCHAEFER, CARLOS E.G.R.

; PEREIRA, ANTONIO BATISTA

Anais da Academia Brasileira de Ciências

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Ago 2018, Volumen 90 Nº 2 Paginas 2001 - 2010

Resumen: En | Texto: En | PDF: En

Abstract High resolution topography (HRT) surveys is an important tool to model landscapes, especially in zones subjected to strong environmental changes, such as Antarctica, where landform is highly influenced by cryoclasty and permafrost melting. The aim of this work was to obtain a high accurate DTM for Keller Peninsula, Maritime Antarctica. The survey study was assessed in the 2014/2015 and 2015/2016 during the austral summer, by using Terrestrial Laser Scanner (TLS). In order to cover 8 km² of the Peninsula, the TLS equipment was installed in 81 different points. Results of the DTM generated by TLS (hereafter, HRT-DTM), and the terrain variables Aspect, Slope and Hillshade obtained were compared with previous models generated by aerophotographic survey (hereafter, APG-DTM). RMSE for the HRT and APG-DTM were 0.726 and 2.397 m, respectively. Spatial resolution of the DTMs was 0.20 m. Morphometric variables obtained from the two methods presented visual differences on the thematic maps, especially related to the Aspect. Generalization was the main process, whereas interpolation occurred for the HRT survey, being the process of choice for the APG method. A large number of points are obtained by the TLS, providing a dense cloud of points, spatially well-distributed, enabling the generalization process to obtain surface models with high performance.

https://doi.org/10.1590/0001-3765201820170296 1436 descargas

13.

Brazilian legislation on genetic heritage harms Biodiversity Convention goals and threatens basic biology research and education
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ALVES, RUY JOSÉ V.

; WEKSLER, MARCELO

; OLIVEIRA, JOÃO A.

; BUCKUP, PAULO A.

; POMBAL JR., JOSÉ P.

; SANTANA, HÉLCIO R.G.

; PERACCHI, ADRIANO LÚCIO

; KELLNER, ALEXANDER W.A.

; ALEIXO, ALEXANDRE

; LANGGUTH, ALFREDO

; ALMEIDA, ALZIRA MARIA P. DE

; ALBERNAZ, ANA LUISA

; RIBAS, CAMILA C.

; ZILBERBERG, CARLA

; GRELLE, CARLOS EDUARDO V.

; ROCHA, CARLOS F.D.

; LAMAS, CARLOS JOSÉ E.

; HADDAD, CÉLIO F.B.

; BONVICINO, CIBELE R.

; PRADO, CYNTHIA P.A.

; LIMA, DANIELA O. DE

; ROSSA-FERES, DENISE C.

; SANTOS, FABRÍCIO R. DOS

; SALIMENA, FÁTIMA REGINA G.

; PERINI, FERNANDO A.

; BOCKMANN, FLÁVIO A.

; FRANCO, FRANCISCO LUÍS

; GIUDICE, GISELE M.L. DEL

; COLLI, GUARINO R.

; VIEIRA, IMA CÉLIA G.

; MARINHO-FILHO, JADER

; WERNECK, JANE M.C.F.

; SANTOS, JORGE A.D. DOS

; NASCIMENTO, JORGE LUIZ DO

; NESSIMIAN, JORGE LUIZ

; CORDEIRO, JOSÉ LUIS P.

; CLARO, KLEBER DEL

; SALLES, LEANDRO O.

; CASATTI, LILIAN

; PY-DANIEL, LUCIA HELENA R.

; SILVEIRA, LUÍS FÁBIO

; TOLEDO, LUÍS FELIPE

; OLIVEIRA, LUIZ F. DE

; MALABARBA, LUIZ ROBERTO

; SILVA, MARCELO D. DA

; COURI, MÁRCIA S.

; MARTINS, MÁRCIO

; TAVARES, MARCOS D.S.

; SOBRAL, MARCOS EDUARDO G.

; VIEIRA, MARCUS VINÍCIUS

; OLIVEIRA, MARIA DE LOURDES A.

; PINNA, MÁRIO DE

; HOPKINS, MICHAEL J.G.

; SOLÉ, MIRCO

; MENEZES, NAÉRCIO A.

; PASSOS, PAULO

; D’ANDREA, PAULO SERGIO

; PINTO, PEDRO C.E.A.

; VIANA, PEDRO L.

; TOLEDO, PETER M.

; REIS, ROBERTO E.

; VILELA, ROBERTO

; BASTOS, ROGÉRIO P.

; COLLEVATTI, ROSANE G.

; CERQUEIRA, RUI

; CASTROVIEJO-FISHER, SANTIAGO

; CARAMASCHI, ULISSES

Anais da Academia Brasileira de Ciências

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Abr 2018, Volumen 90 Nº 2 Paginas 1279 - 1284

Resumen: En | Texto: En | PDF: En

https://doi.org/10.1590/0001-3765201820180460 7311 descargas

14.

Natural products assessed in animal models for orofacial pain – a systematic review
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Siqueira-Lima, Pollyana S.

; Silva, Juliane C.

; Quintans, Jullyana S.S.

; Antoniolli, Angelo R.

; Shanmugam, Saravanan

; Barreto, Rosana S.S.

; Santos, Márcio R.V.

; Almeida, Jackson R.G.S.

; Bonjardim, Leonardo R.

; Menezes, Irwin R.A.

; Quintans-Júnior, Lucindo J.

Revista Brasileira de Farmacognosia

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Feb 2017, Volumen 27 Nº 1 Paginas 124 - 134

Resumen: En | Texto: En | PDF: En

ABSTRACT Orofacial pain is related to tissues of the head, face, neck and all the intraoral structures; it is rather debilitating to the patient and also difficult to treat. There are relatively few studies dedicated to the use of natural products to alleviate orofacial pain in preclinical experiment models (performed in experimental animals which provide support for clinical trials). Main objectives of the present systematic review summarize the studies on natural products assessed in animal models for orofacial pain seeking to give evidence to future development of new pharmaceutical products to manage the orofacial pain. Our review includes a thorough search of literature using the terms of orofacial pain, facial pain, medicinal plants and natural products. This search was performed using to retrieve English language articles in Medline-PubMed, Scopus and Web of Science. A total of eighteen studies were included in our survey for the inclusion criteria. Firstly, this review identified 210 citations from electronic search, after removal of duplicates and screening for relevant titles and abstracts, a total of eighteen articles were selected to the inclusion criteria established. Our findings suggest that natural products can be a promising or a trump tool for the development of new drugs to treat orofacial pain conditions, but the researchers that deal with experimental preclinical trials of new drugs (including natural products or synthetic drugs) for orofacial pain conditions urgently need to show translational evidence (with clinical approach) of these compounds.

https://doi.org/10.1016/j.bjp.2016.06.005 1267 descargas

15.

Evaluation of clinical tests and magnetic resonance imaging for knee meniscal injuries: correlation with video arthroscopy
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Antunes, Leonardo Côrtes

; Souza, José Marcio Gonçalves de

; Cerqueira, Nelson Baisi

; Dahmer, Cleiton

; Tavares, Breno Almeida de Pinho

; Faria, Ângelo José Nacif de

Revista Brasileira de Ortopedia

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2017, Volumen 52 Nº 5 Paginas 582 - 588

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RESUMO Objetivo: Determinar a especificidade, sensibilidade, acurácia, razão de verossimilhança e correlação dos achados dos testes meniscais e da ressonância magnética (RM) com a videoartroscopia do joelho. Métodos: Estudo transversal feito entre junho e dezembro de 2015. Avaliaram-se 84 pacientes selecionados para tratamento videoartroscópico das lesões meniscais (LM). Dois ortopedistas especializados em cirurgia do joelho e um residente em ortopedia fizeram o exame físico com testes específicos. Os resultados obtidos e laudos da RM foram comparados com os achados da videoartroscopia. Os dados foram tratados no programa estatísticoR. Resultados: O teste de Steinmann I, foi mais específico, com especificidade de 86% e 91% para lesões de menisco medial (LMM) e lesões de menisco lateral (LML), respectivamente. Quanto à acurácia, o teste de dor à palpação da interlinha articular (DPIA) apresentou valores de 67% e 73% para detecção de LMM e LML, respectivamente. O teste de DPIA apresentou maior sensibilidade, com 77% de chance de detectar LMM. A análise do conjunto de três testes (McMurray, DPIA e Steinmann I, ) comparada com a videoartroscopia apresentou 85% de sensibilidade para as LMM e 70% de sensibilidade para as LML. A RM apresentou maior especificidade para o diagnóstico de LMM e LML; 82% e 91%, respectivamente.. Conclusão: O conjunto dos três testes apresentou melhores resultados se comparado com os testes isolados e pode ser associado à RM para elaboração de um diagnóstico efetivo. Entretanto, são necessários outros estudos que auxiliem na elaboração de um protocolo para padronizar a avaliação diagnóstica.

ABSTRACT Objective: To determine the specificity, sensitivity, accuracy, likelihood, and correlation of the findings of meniscal tests and magnetic resonance imaging (MRI) to knee video arthroscopy., Methods: A cross-sectional study, conducted between June and December 2015, which evaluated 84 patients with meniscal tears (MT) selected for video arthroscopy. Two orthopedic trainees and a resident performed a physical examination with specific tests. The results and reports from MRI were compared with arthroscopy findings. The data were analyzed in the statistical program , R. Results: The Steinmann I, test was the most specific, with specificity of 86% and 91% for medial meniscus tears (MMT) and lateral meniscus tears (LMT), respectively. With regard to accuracy, the pain test on palpation of the joint interline (PPJI) showed values of 67% and 73% for detection of MMT and LMT, respectively. The PPJI test showed higher sensitivity, with a 77% chance of detecting MMT. Analysis of the set of three tests (McMurray, PPJI, and Steinmann , I, ) compared to arthroscopy showed 85% sensitivity for MMT and 70% sensitivity for LMT. MRI showed a greater specificity for the diagnosis of MMT and LMT; the values were 82% and 91%, respectively. Conclusion: The combination of the three tests shows better results compared to the isolated tests and thus can be associated to the MRI to make an effective diagnosis. However, further studies assisting in the development of a protocol to standardize diagnostic evaluation are required.

https://doi.org/10.1016/j.rboe.2016.09.009 4123 descargas

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