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ABSTRACT Compaction caused by mechanization affects soil quality and, consequently, the development of crops. This study aimed to evaluate the effect of different degrees of soil compaction on the physiology, morphology, and anatomy of different coffee cultivars in a controlled environment. The experiment was carried out in a greenhouse, with randomized block design in a 5 × 5 factorial arrangement, with five coffee cultivars (Arara, Catuaí Amarelo IAC 62, Catuaí Vermelho 144, MGS Paraíso 2 and Mundo Novo IAC 379-19) and five degrees of compaction (68, 74, 80, 86 and 92 %), with four repetitions, totaling 100 experimental units. The following variables were evaluated in the aboveground biomass: plant height, number of leaves, diameter of the orthotropic branch, fresh mass of leaves and stem, leaf area, gas exchange, and chlorophyll a and b index; in the roots: length, surface area, volume, diameter of fine and coarse roots, fresh and dry mass of roots, as well as anatomical characteristics. Results showed that soil with degrees of compaction above 80 % negatively affected the variables evaluated. Catuaí Vermelho 144 presented the worst performance regardless of the degree of compaction, while Arara and MGS Paraíso 2 showed the best performance under the evaluated compaction degrees. Anatomical structure of the roots was modified with soil compaction, and no differences were observed among cultivars.

https://doi.org/10.36783/18069657rbcs20230046

A Theoretical Model to Discuss Tax Avoidance Based on Game Theory
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Gomes, Antônio Paulo Machado

; Cunha, Jacqueline Veneroso Alves da

; Francisco, José Roberto de Souza

; Lara, Fabiano Teodoro de Rezende

BBR. Brazilian Business Review

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2023, Volumen 20 Nº 3 Paginas 281 - 300

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Existe no Brasil uma linha de pesquisa consolidada que buscou identificar as proxies determinantes da agressividade fiscal das empresas listadas na B3. Contudo, nenhum desses estudos buscou identificar o instrumento utilizado pelas empresas brasileiras para realizar a agressividade fiscal. Portanto, esta pesquisa busca preencher essa lacuna ao demonstrar que a agressividade fiscal tem como fundamento a complexidade tributária brasileira que proporciona subsídios para evitar ou postergar o pagamento dos tributos. Além disso, este estudo é o primeiro estudo contábil a demonstrar que os parcelamentos especiais reduzem o valor presente dos tributos devidos pelos contribuintes incentivando-os à agressividade fiscal. Através dos fundamentos da Teoria dos Jogos, esta pesquisa demonstra o custo-benefício da agressividade fiscal na maximização do lucro da desobediência tributária. Foram examinadas as melhores decisões estratégicas no jogo da desobediência tributária diante da complexidade tributária e dos parcelamentos especiais vividos no Brasil. Verificou-se nesse jogo que o único equilíbrio de NASH é a desobediência tributária uma vez que é a única opção com alguma chance de remuneração. Portanto, esta pesquisa contribui substancialmente para compreensão do comportamento empresarial diante das características tributárias brasileiras, bem como fornece subsídios para incentivar uma reforma tributária que reduz a complexidade tributária atual. B3 B Contudo Portanto disso incentivandoos incentivando Jogos custobenefício custo benefício Verificouse Verificou se remuneração atual

Abstract A consolidated research line in Brazil identified the proxies for determining the tax aggressiveness of companies listed on the B3 stock exchange. However, none of these studies identified the instrument used by Brazilian companies to carry out tax aggressiveness. Thus, our research seeks to fill this gap by demonstrating that fiscal aggressiveness results from the Brazilian tax complexity, that providing prerogatives to avoid or delay tax payments. Besides, this study is the first accounting study to demonstrate that special installments reduce the actual value of taxes owed by taxpayers, encouraging them to be tax aggressive. Through the foundations of Game Theory, this research demonstrates the cost-benefit of tax aggressiveness in maximizing the profit of tax avoidance. We examined the best strategic decisions in the tax avoidance game concerning the tax complexity and special installments experienced in Brazil. In this game, the only NASH equilibrium is tax avoidance since it is the only option with a chance of remuneration. Therefore, this research contributes to understanding business behavior concerning the Brazilian tax system and provides subsidies to encourage reform of the current tax complexity. B exchange However Thus payments Besides taxpayers aggressive Theory costbenefit cost benefit remuneration Therefore

https://doi.org/10.15728/bbr.2023.20.3.3.en

Precision of wearable heart rate to predict oxygen uptake in endurance vs sprint-trained runners
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Garrido, Nuno Domingos

; Aidar, Felipe

; Vilaça-Alves, José

; Oliveira, Diogo Roberto

; Szabo, Paul

; Reis, Victor Machado

Motricidade

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Dic 2022, Volumen 18 Nº 2 Paginas 215 - 218

Resumen: En | Texto: En | PDF: En

ABSTRACT The present study aimed to assess the precision of oxygen uptake with heart rate regression during treadmill running in highly trained runners. Twenty national and international level male runners were divided into two equal groups. Group A was formed of 10 sprinters (31.5± 4.7 years, height 1.74± 0.04 m and mass 61.8± 5.2 kg), and group B comprised 10 endurance runners (25.7± 4.5 years, height 1.77± 0.08 m and mass 71.2± 5.8 kg). Each participant performed six min bouts at a constant velocity on a level treadmill, with each bout at an increased running velocity. The starting velocity was 3.33 m·s-1, with a 0.56 m·s-1 increase in each subsequent bout. VO2 and HR were measured during all runs. Mean peak VO2 and mean peak HR for Group A were, respectively, 71.7± 7.0 mL·kg-1·min-1 and 179.8± 12.7 beats·min-1, while for Group B were 67.3± 4.9 mL·kg-1·min-1 and 198.2± 9.8 beats·min-1. The linearity of the regressions between VO2 and HR in both groups was very high (R2= 0.97 and R2=0.76) with small standard errors of regression. Despite a stronger correlation in endurance-trained athletes, the results of the present study indicate that it is possible to use HR as an indicator of exercise intensity in individuals trained in both speed and longer distances.

https://doi.org/10.6063/motricidade.27172

Calidad de vida relacionada con la salud de personas con hemofilia en el noreste de Brasil
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Vieira Nobre, Stefane

; Alves Pinto, Antonio Germane

; da Silva Filho, José Adelmo

; Caldas Leite, Thiáskara Ramile

; da Silva, Marcelo Gurgel Carlos

Revista Cubana de Hematología, Inmunología y Hemoterapia

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Jun 2022, Volumen 38 Nº 2 elocation e1589

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Hemophilia is characterized by the occurrence of frequent bleeding and serious musculoskeletal conditions in patients that cause physical, social and psychological damage and directly affect their health-related quality of life. Objective: To evaluate the quality of life of people with hemophilia in the northeast of Brazil. Methods: Quantitative cross-sectional epidemiological study conducted with 13 people with hemophilia from a Blood Bank in northeastern Brazil. Data collection was performed by applying a sociodemographic and clinical questionnaire and Haem-A-Qol, used to assess the quality of life of people with hemophilia. Raw and mean values were calculated overall for all domains and then for each domain so that they could be displayed. Results: A total average of 30,94 was obtained in relation to the ten domains evaluated. The domains with the highest averages were "physical health" with 49,23 and "coping" with 35,89 and with the lowest average was "family planning". Conclusions: The research participants have an unsatisfactory quality of life in relation to physical health and coping, and satisfactory in relation to relationships and sexuality.

RESUMEN Introducción: La hemofilia se caracteriza por la ocurrencia de hemorragias frecuentes y afecciones del aparato locomotor graves en los pacientes que causan daños físicos, sociales y psicológicos y afecta directamente su calidad de vida relacionada con la salud. Objetivo: Evaluar la calidad de vida de personas con hemofilia en el noreste de Brasil. Métodos: Estudio epidemiológico transversal cuantitativo realizado con 13 personas con hemofilia de un Banco de Sangre en el noreste de Brasil. La recolección de datos se realizó mediante la aplicación de un cuestionario sociodemográfico y clínico y de Haem-A-Qol, utilizado para evaluar la calidad de vida de las personas con hemofilia. Los valores brutos y medios se calcularon en general para todos los dominios y luego para cada dominio para que pudieran mostrarse. Resultados: Se obtuvo un promedio total de 30,94 en relación a los diez dominios evaluados. Los dominios con los promedios más altos fueron “salud física” con 49,23 y “afrontamiento” con 35,89 y con el promedio más bajo fue “planificación familiar”. Conclusiones: Los participantes de la investigación tienen una calidad de vida insatisfactoria en relación con la salud física y el afrontamiento y, satisfactoria en relación con las relaciones y la sexualidad.

Comparison of digital games as a cognitive function assessment tool for current standardized neuropsychological tests
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Goulart, Ananaira Alves

; Lucatelli, André

; Silveira, Paulo Sergio Panse

; Siqueira, José de Oliveira

; Pereira, Valéria Fontanelle Angelim

; Carmona, Maria José Carvalho

; Valentin, Livia Stocco Sanches

; Vieira, Joaquim Edson

Brazilian Journal of Anesthesiology

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Feb 2022, Volumen 72 Nº 1 Paginas 13 - 20

Resumen: En | Texto: En | PDF: En

Abstract Objective: Cognitive dysfunction may occur postoperatively. Fast and efficient assessment of Postoperative Cognitive Dysfunction (POCD) can minimize loss of quality of life, and therefore, a study comparing a digital game with standard neuropsychological tests to assess executive, mnemonic, and attention functions to evaluate POCD seems to be relevant both for research and clinical practice. Methods: A battery of standardized tests and a digital game (MentalPlus®) were administered to 60 patients at the Central Institute of Hospital das Clínicas in São Paulo (36 women and 24 men), with ages between 29 and 82 years, preand post-surgery performed under anesthesia. Correlation and linear regression model were used to compare the scores obtained from the standardized tests to the scores of the six executive and cognitive functions evaluated by the game (shortand long-term memory, selective and alternating attention, inhibitory control, and visual perception). Results: After correlation analysis, a statistically significant result was found mainly for the correlation between the scores from the phase of the digital game assessing the visuoperception function and the scores from the A and B cards of the Stroop Test (p < 0.001, r = 0.99 and r = 0.64, respectively), and the scores from TMTA (p = 0.0046, r = 0.51). We also found a moderate correlation between the phase of the game assessing short-memory function and VVLT (p < 0.001, r = 0.41). No statistically significant correlations were found for the other functions assessed. Conclusion: The digital game provided scores in agreement with standardized tests for evaluating visual perception and possibly short-term memory cognitive functions. Further studies are necessary to verify the correlation of other phases of the digital game with standardized tests assessing cognitive functions.

https://doi.org/10.1016/j.bjane.2021.06.027

Organomineral fertilizers potentiate Atlantic potato cultivation
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Oliveira, Roberta C.

; Luz, Jose Magno Q.

; Lana, Regina Maria Q.

; Alves, Gustavo O.

; Ferraz-Almeida, Risely

; Camargo, Reginaldo

International journal of agriculture and natural resources

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2022, Volumen 49 Nº 3 Paginas 157 - 168

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Analyses of potential sources and products that aim to balance nutrients in soil and plants; improve physical, mineral, and biological attributes of soil; and reduce environmental impacts require greater attention. Therefore, the aim of this study was to evaluate the agronomic efficiency of organomineral fertilizers (OMFs) in Atlantic potato cultivars. The experimental design was a randomized complete block design, with four treatments and six replicates. The treatments consisted of NPK mineral fertilizers (recommended according to soil analysis and nutritional crop requirements) as a control and NPK plus OMF according to composition and form of application (planting, ridging, and leaf), referred to as managements A and B, which indicate the amount of nutrients that the plants received. Therefore, treatments with OMF were designated as follows: P-OMF(A): organomineral fertilizer management applied through the planting furrow; PR-OMF (B): organomineral fertilizer management applied through the planting and ridging, and PR-OMF (B) + L-OMF (B): organomineral fertilizer management applied through the planting and ridging and by leaf application. The applications of P-OMF (A) and PR-OMF (B) + L-OMF (B) resulted in positive effects on special class production and total productivity of Atlantic potato tubers, which increased by 12% to 16% and 11% to 15.5%, respectively. The application of PR-OMF (B) + L-OMF (B) improved the soluble solid content by 2.7% compared to the control (absence of OMF application). Therefore, organomineral fertilizers have the potential to improve the quantitative and qualitative attributes of potatoes.

Resumen El análisis de las posibles fuentes y productos que apuntan a equilibrar los nutrientes en el suelo y las plantas, mejorar los atributos físicos, minerales y biológicos del suelo y reducir los impactos ambientales necesitan más atención. En este sentido, el objetivo de este estudio fue evaluar la eficiencia agronómica de los fertilizantes organominerales (OMF) en papa, cultivar Atlantic. El diseño experimental fue un bloque completo aleatorizado, con cuatro tratamientos y seis repeticiones. Los tratamientos consistieron en el control -fertilizantes minerales NPK (recomendado de acuerdo con el análisis del suelo y los requerimientos nutricionales del cultivo); y NPK más OMF de acuerdo con: composición y forma de aplicación (plantación, crestas y hojas), que fue llamado a lo manejo A y B. Lo manejo A y B se relaciona con las tasas de nutrientes que recibieron las plantas. Por lo tanto, los tratamientos con OMF se designaron como: P-OMF (A): manejo de fertilizantes organominerales (A) aplicado en el surco de siembra; PR-OMF (B): manejo de fertilizantes organominerales (B) aplicada en la siembra y la formación de surcos y PR-OMF + L-OMF (C): manejo de fertilizantes organominerales (B) aplicada en la siembra, la formación de surcos y la aplicación de hojas. Las aplicaciones de P-OMF (A) y PR- PR-OMF (B)+ L-OMF (B) dan como resultado una acción positiva para la producción de Clase Especial y la productividad total de los tubérculos del cultivar Atlantic, con incrementos entre 12 y 16% y 11 a 15.5%, respectivamente. La aplicación de PR-OMF (B)+ L-OMF (B) mejora en un 2.7% el contenido de sólidos solubles, en comparación con la ausencia de aplicación de OMF. Por lo tanto, los fertilizantes organominerales presentan potencial para mejorar los atributos cuantitativos y cualitativos de las papas.

https://doi.org/10.7764/ijanr.v49i3.2302

Bioactive, technological-functional potential and morphological structures of passion fruit albedo (Passiflora edulis)
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ROSÁRIO, Rosely Carvalho do

; SOARES, Stephanie Dias

; MARTINS, Mayara Galvão

; NASCIMENTO, Francisco das Chagas Alves do

; SILVA JUNIOR, José Otávio Carrera

; TEIXEIRA-COSTA, Bárbara Elisabeth

; FIGUEIRA, Marcela de Souza

; SANTOS, Orquídea Vasconcelos dos

Food Science and Technology

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2022, Volumen 42 elocation e22222

Resumen: En | Texto: En | PDF: En

Abstract Agroindustrial disposal generates tons of passion fruit albedo during pulp and juice processing. The reduction of this environmental pollution potential and its use involves research such as this one, which aims to determine the bioactive compounds in the passion fruit albedo (Passiflora edulis), its technological, functional potential and its morphological structures, aiming at food application. The methodologies applied followed internationally accepted and recommended guidelines. The results showed that the albedo flour obtained a yield of 9.76%, and from this, a semifine powder flour was prepared (75.8%), with 4.95% moisture, 40.72% reducing sugars, water activity of 0.37, pH of 5.29, total titratable acidity of 0.99 and total soluble solids of 1.5 °Brix. In addition, the presence of bioactive compounds such as polyphenols (18.88 mg AGE/100 g), flavonoids (13.51 mg/100 g), anthocyanins (1.74 mg/100 g) and chlorophyll b (69.65 mg/100 g) was evidenced, highlighting a considerable amount of vitamin C (377.36 mg/100 g) and pectin concentration (40.5%). In addition, the presence of bioactive compounds such as polyphenols (18.88 mg AGE/100 g), flavonoids (13.51 mg/100 g), anthocyanins (1.74 mg/100 g) and chlorophyll b (69.65 mg/100 g) was evidenced, highlighting a considerable amount of vitamin C (377.36 mg/100 g) and pectin concentration (40.5%).

https://doi.org/10.1590/fst.22222

Aluminium toxicity: oxidative stress during germination and early development in purple maize
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Alves, Rafael Mateus

; Silva, Monalisa Alves Diniz da

; Hermínio, Pedro José

; Silva, Elania Freire da

; Araújo, Anna Beatriz Nogueira de

; Silva, Gabriel Italo Novaes da

Revista Ciência Agronômica

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2022, Volumen 53 elocation e20207676

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O milho roxo é fonte de pigmentos naturais que podem ser utilizados para diversas finalidades industriais, no entanto a contaminação dos solos por alumínio afeta sua produção. Diante do exposto, o objetivo foi avaliar o efeito da toxidez por alumínio associado a diferentes temperaturas sobre a germinação das sementes e desenvolvimento inicial de plântulas de milho roxo, por meio da germinação, crescimento inicial das plântulas e indicadores de danos oxidativos. O delineamento utilizado foi inteiramente casualizado, com esquema fatorial 5×2 (concentrações × temperaturas). Os parâmetros avaliados foram porcentagem de germinação, comprimento e massa seca total, da parte aérea, do sistema radicular e indicadores de danos oxidativos (clorofilas totais, a, b, carotenoides totais e peroxidação de lipídeos) na fase de plântula. As concentrações de cloreto de alumínio não interferem na germinação de sementes de milho roxo. O comprimento, massa seca, clorofilas totais, a, b e carotenoides totais das plântulas normais de milho roxo sofrem redução e acréscimos na peroxidação lipídica com o aumento das concentrações de alumínio. O estresse por toxidez do alumínio em plântulas de milho roxo é detectado pelos indicadores bioquímicos (clorofilas totais, a, b, carotenoides totais e peroxidação de lipídeos).

ABSTRACT Purple maize is a source of natural pigments that can be used for various industrial purposes; however, soil contamination from aluminium affects production. The aim of this study was to evaluate the effect of aluminium toxicity associated with different temperatures on seed germination and initial development in purple maize seedlings, through germination, initial seedling growth and indicators of oxidative damage. The experimental design was completely randomised in a 5×2 factorial scheme (concentrations × temperatures). The parameters under evaluation were germination percentage, length and total dry weight of the root system and shoots, and indicators of oxidative damage (chlorophyll a, chlorophyll b and total chlorophyll, total carotenoids and lipid peroxidation) at the seedling stage. Aluminium chloride concentrations have no effect on seed germination in purple maize. With increasing aluminium concentrations, the length, dry weight, chlorophyll a, chlorophyll b, total chlorophyll and total carotenoids of normal purple maize seedlings are reduced, while lipid peroxidation increases. Aluminium toxicity stress in purple maize seedlings can be detected using biochemical indicators (chlorophyll a, chlorophyll b and total chlorophyll, total carotenoids and lipid peroxidation).

https://doi.org/10.5935/1806-6690.20220039

Organic fertilization for the beginning of sweet potato (Ipomoea batatas L.) cultivation in savanna soils
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Dias, Elton da Silva

; Monteiro Neto, João Luiz Lopes

; Dresch, Brito Luís

; Rodrigues, Rannyonara Oliveira

; Araújo, Wellington Farias

; Chagas, Edvan Alves

; Maia, Sonicley da Silva

; Siqueira, Raphael Henrique da Silva

; Chagas, Pollyana Cardoso

; Tadashi Sakazaki, Roberto

; Silva, Edgley Soares-da

; Albuquerque, José de Anchieta Alves de

; Abanto-Rodríguez, Carlos

Revista Chapingo. Serie horticultura

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Abr 2021, Volumen 27 Nº 1 Paginas 27 - 42

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Due to limited information on sweet potato (Ipomoea batatas L.) cultivation in uncultivated savanna areas, the objective of this research was to determine the ideal dose and type of organic fertilizer for sweet potato cultivation in savanna soils with no history of use. In four experiments, the following fertilizer doses were tested: cattle manure (0, 10, 20, 30, and 40 t·ha-1), poultry manure (0, 5, 10, 15, and 20 t·ha-1), compost A (0, 0.75, 1.5, 2.25, and 3.0 t·ha-1), and compost B (0, 0.75, 1.5, 2.25, and 3.0 t·ha-1). The fifth experiment consisted of an organic fertilizer efficiency test using applications already recommended for sweet potato crops, which resulted in six treatments: control (without organic fertilization), cattle manure (20 t·ha-1), poultry manure (10 t·ha-1), compost A (1.5 t·ha-1), compost B (1.5 t·ha-1), and compost C (0.375 t·ha-1). In the first four experiments, the products and their recommended doses were defined in order of production efficiency, as follows: poultry manure (doses between 13 and 20 t·ha-1) > cattle manure (doses between 30 and 40 t·ha-1) > compost B (doses between 0.75 and 2.25 t·ha-1) = compost A (doses between 2.25 and 3.00 t·ha-1). The fifth experiment concluded that: 1) poultry manure was the most suitable starting point for sweet potato cultivation in savanna soils and 2) sweet potato yield was directly linked to the commercial root mass, number of commercial roots, and branch productivity, which, in turn, were maximized by an increase in organic matter and satisfactory amounts of phosphorus in the soil.

Resumen Debido a la limitada información sobre el cultivo de camote (Ipomoea batatas L.) en áreas silvestres de la sabana, el objetivo de este estudio fue determinar la dosis ideal y el tipo de fertilizante orgánico para el cultivo de camote en suelos de la sabana sin antecedentes de explotación. Se probaron diferentes dosis de fertilizantes en cuatro experimentos: estiércol de ganado (0, 10, 20, 30 y 40 t·ha-1), pollinaza (0, 5, 10, 15 y 20 t·ha-1), compost A (0, 0.75, 1.5, 2.25 y 3.0 t·ha-1) y compost B (0, 0.75, 1.5, 2.25 y 3.0 t·ha-1). El quinto experimento consistió en una prueba de eficiencia de fertilizantes orgánicos utilizando dosis recomendadas para el cultivo de camote, lo cual resultó en seis tratamientos: testigo (sin fertilización orgánica), estiércol de ganado (20 t·ha-1), pollinaza (10 t·ha-1), compost A (1.5 t·ha-1), compost B (1.5 t·ha-1) y compost C (0.375 t·ha-1). En los primeros cuatro experimentos, los productos y dosis recomendadas se definieron en orden de eficiencia de producción: pollinaza (dosis entre 13 y 20 t·ha-1) > estiércol de ganado (dosis entre 30 y 40 t·ha-1) > compost B (dosis entre 0.75 y 2.25 t·ha-1) = compost A (dosis entre 2.25 y 3.00 t·ha-1). Con el quinto experimento se concluyó que: 1) la pollinaza fue el fertilizante inicial más adecuado para el cultivo de camote en suelos de la sabana y 2) el rendimiento del camote estuvo vinculado directamente a la masa de las raíces comerciales, el número de raíces comerciales y la productividad de tallos; las cuales, a su vez, fueron maximizadas al incrementar la materia orgánica y las cantidades de fósforo en el suelo.

https://doi.org/10.5154/r.rchsh.2020.05.011 1112 descargas

10.

BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 2): UPDATE ON TREATMENT
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BARCHI, Leandro Cardoso

; RAMOS, Marcus Fernando Kodama Pertille

; DIAS, André Roncon

; FORONES, Nora Manoukian

; CARVALHO, Marineide Prudêncio de

; CASTRO, Osvaldo Antonio Prado

; KASSAB, Paulo

; COSTA-JÚNIOR, Wilson Luiz da

; WESTON, Antônio Carlos

; ZILBERSTEIN, Bruno

; Ferraz, Álvaro Antônio Bandeira

; ZeideCharruf, Amir

; Brandalise, André

; Silva, André Maciel da

; Alves, Barlon

; Marins, Carlos Augusto Martinez

; Malheiros, Carlos Alberto

; Leite, Celso Vieira

; Bresciani, Claudio José Caldas

; Szor, Daniel

; Mucerino, Donato Roberto

; Wohnrath, Durval R.

; JirjossIlias, Elias

; Martins Filho, Euclides Dias

; PinatelLopasso, Fabio

; Coimbra, Felipe José Fernandez

; Felippe, Fernando E. Cruz

; Tomasisch, Flávio Daniel Saavedra

; Takeda, Flavio Roberto

; Ishak, Geraldo

; Laporte, Gustavo Andreazza

; Silva, Herbeth José Toledo

; Cecconello, Ivan

; Rodrigues, Joaquim José Gama

; Grande, José Carlos Del

; Lourenço, Laércio Gomes

; Motta, Leonardo Milhomem da

; Ferraz, Leonardo Rocha

; Moreira, Luis Fernando

; Lopes, Luis Roberto

; Toneto, Marcelo Garcia

; Mester, Marcelo

; Rodrigues, Marco Antônio Gonçalves

; Franciss, Maurice Youssef

; AdamiAndreollo, Nelson

; Corletta, Oly Campos

; Yagi, Osmar Kenji

; Malafaia, Osvaldo

; Assumpção, Paulo Pimentel

; Savassi-Rocha, Paulo Roberto

; Colleoni Neto, Ramiro

; Oliveira, Rodrigo Jose de

; AissarSallun, Rubens Antonio

; Weschenfelder, Rui

; Oliveira, Saint Clair Vieira de

; Abreu, Thiago Boechat de

; Castria, Tiago Biachi de

; Ribeiro Junior, Ulysses

; Barra, Williams

; Freitas Júnior, Wilson Rodrigues de

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Métricas del periódico
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- SciELO Analytics

2021, Volumen 34 Nº 1 elocation e1563

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Racional: O II Consenso Brasileiro de Câncer Gástrico da Associação Brasileira de Câncer Gástrico ABCG (Parte 1) foi recentemente publicado. Nesta ocasião inúmeros especialistas que atuam no tratamento desta doença expressaram suas opiniões diante declarações apresentadas. Objetivo: Apresentar as Diretrizes da ABCG (Parte 2) quanto às indicações de tratamento cirúrgico, técnicas operatórias, extensão de ressecção e terapia combinada. Métodos: Para formulação destas diretrizes os autores realizaram extensa e atual revisão referente a cada declaração presente no II Consenso, utilizando as bases Medline/PubMed, Cochrane Library e SciELO, inicialmente com os seguintes descritores: câncer gástrico, gastrectomia, linfadenectomia, terapia combinada. Ainda, cada declaração foi classificada de acordo com o nível de evidência e grau de recomendação. Resultados: Das 43 declarações presentes neste estudo, 11 (25,6%) foram classificadas com nível de evidência A, 20 (46,5%) B e 12 (27,9%) C. Quanto ao grau de recomendação, 18 (41,9%) declarações obtiveram grau de recomendação 1, 14 (32,6%) 2a, 10 (23,3%) 2b e um (2,3%) 3. Conclusão: O complemento das diretrizes aqui presentes possibilita que cirurgiões e oncologistas que atuam no combate ao câncer gástrico possam oferecer o melhor tratamento possível, de acordo com as condições locais disponíveis.

ABSTRACT Background : The II Brazilian Consensus on Gastric Cancer of the Brazilian Gastric Cancer Association BGCA (Part 1) was recently published. On this occasion, countless specialists working in the treatment of this disease expressed their opinion in the face of the statements presented. Aim : To present the BGCA Guidelines (Part 2) regarding indications for surgical treatment, operative techniques, extension of resection and multimodal treatment. Methods: To formulate these guidelines, the authors carried out an extensive and current review regarding each declaration present in the II Consensus, using the Medline/PubMed, Cochrane Library and SciELO databases initially with the following descriptors: gastric cancer, gastrectomy, lymphadenectomy, multimodal treatment. In addition, each statement was classified according to the level of evidence and degree of recommendation. Results : Of the 43 statements present in this study, 11 (25,6%) were classified with level of evidence A, 20 (46,5%) B and 12 (27,9%) C. Regarding the degree of recommendation, 18 (41,9%) statements obtained grade of recommendation 1, 14 (32,6%) 2a, 10 (23,3%) 2b e one (2,3%) 3. Conclusion : The guidelines complement of the guidelines presented here allows surgeons and oncologists who work to combat gastric cancer to offer the best possible treatment, according to the local conditions available.

https://doi.org/10.1590/0102-672020210001e1563 768 descargas

11.

Hepatitis E virus infection increases the risk of diabetes and severity of liver disease in patients with chronic hepatitis C virus infection
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Zitelli, Patricia Momoyo Yoshimura

; Gomes-Gouvêa, Michele

; Mazo, Daniel F.

; Singer, Julio da Motta

; Oliveira, Claudia P.M.S.

; Farias, Alberto Queiroz

; Pinho, João Renato

; Tanigawa, Ryan Yukimatsu

; Alves, Venâncio Avancini Ferreira

; Carrilho, Flair José

; Pessoa, Mário Guimarães

Clinics

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2021, Volumen 76 elocation e3270

Resumen: En | Texto: En | PDF: En

OBJECTIVES: Co-infection with hepatitis A or B viruses may aggravate liver injury in patients infected with hepatitis C virus (HCV). However, few studies have assessed co-infection with hepatitis E virus (HEV) and HCV. Therefore, this study aimed to assess the prevalence and impact of HEV infection among Brazilian patients with chronic HCV infection. METHODS: This observational study included adult patients with chronic HCV infection who were naive to antiviral therapy from January 2013 to March 2016. A total of 181 patients were enrolled, and HEV serology and PCR were performed for all patients. RESULTS: Seropositivity for anti-HEV IgG was detected in 22 (12.0%) patients and anti-HEV immunoglobulin M in 3 (1.6%). HEV RNA showed inconclusive results in nine (4.9%) patients and was undetectable in the remaining patients. HEV serology positive patients had more severe liver disease, characterized by liver fibrosis ≥3 versus ≤2 (p<0.001), Aspartate Aminotransferase-to-Platelet Ratio Index of ≥1.45 (p=0.003), and Fibrosis-4 score of ≥3.25 (p=0.001). Additionally, the odds of HEV-positive patients developing diabetes mellitus were 3.65 (95% CI 1.40-9.52) times the corresponding odds of HEV-negative patients. A case-control-based histological analysis (n=11 HEV-HCV-positive patients and n=22 HCV-positive patients) showed no significant differences between the groups. CONCLUSIONS: This prevalence is higher than that reported in previous studies of the general population in Brazil. Thus, HEV infection may influence the severity of liver disease and may represent an additional risk of developing diabetes mellitus in patients with HCV infection.

https://doi.org/10.6061/clinics/2021/e3270

12.

Valor Prognóstico da Troponina T e do Peptídeo Natriurético Tipo B em Pacientes Internados por COVID-19
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Almeida Junior, Gustavo Luiz Gouvêa de

; Braga, Fabricio

; Jorge, José Kezen

; Nobre, Gustavo Freitas

; Kalichsztein, Marcelo

; Faria, Paula de Medeiros Pache de

; Bussade, Bruno

; Penna, Guilherme Loures

; Alves, Vitor Oliveira

; Pereira, Marcella Alecrim

; Gorgulho, Paula de Castro

; Faria, Milena Rego dos Santos Espelta de

; Drumond, Luis Eduardo

; Carpinete, Fabrini Batista Soares

; Neno, Ana Carolina Lessa Brandão

; Neno, Augusto César de Araújo

Arquivos Brasileiros de Cardiologia

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Oct 2020, Volumen 115 Nº 4 Paginas 660 - 666

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: A COVID-19 causa grave acometimento pulmonar, porém o sistema cardiovascular também pode ser afetado por miocardite, insuficiência cardíaca e choque. A elevação de biomarcadores cardíacos tem sido associada a um pior prognóstico. Objetivos: Avaliar o valor prognóstico da Troponina T (TnT) e do peptídeo natriurético tipo B (BNP) em pacientes internados por Covid-19. Métodos: Amostra de conveniência de pacientes hospitalizados por COVID-19. Foram coletados dados dos prontuários com o objetivo de avaliar a relação da TnT e o BNP medidos nas primeiras 24h de admissão com o desfecho combinado (DC) óbito ou necessidade de ventilação mecânica. Análise univariada comparou os grupos com e sem DC. Modelo multivariado de Cox foi utilizada para determinar preditores independentes do DC. Resultados: Avaliamos 183 pacientes (idade=66,8±17 anos, sendo 65,6% do sexo masculino). Tempo de acompanhamento foi de 7 dias (1 a 39 dias). O DC ocorreu em 24% dos pacientes. As medianas de TnT e BNP foram 0,011 e 0,041 ng/dl (p<0,001); 64 e 198 pg/dl (p<0,001) respectivamente para os grupos sem e com DC. Na análise univariada, além de TnT e BNP, idade, presença de doença coronariana, saturação de oxigênio, linfócitos, dímero-D, proteína C reativa titulada (PCR-t) e creatinina, foram diferentes entre os grupos com e sem desfechos. Na análise multivariada boostraped apenas TnT (1,12[IC95%1,03-1,47]) e PCR-t (1,04[IC95%1,00-1,10]) foram preditores independentes do DC. Conclusão: Nas primeiras 24h de admissão, TnT, mas não o BNP, foi marcador independente de mortalidade ou necessidade de ventilação mecânica invasiva. Este dado reforça ainda mais a importância clínica do acometimento cardíaco da COVID-19. (AArq Bras Cardiol. 2020; 115(4):660-666)

Abstract Background: COVID-19 causes severe pulmonary involvement, but the cardiovascular system can also be affected by myocarditis, heart failure and shock. The increase in cardiac biomarkers has been associated with a worse prognosis. Objectives: To evaluate the prognostic value of Troponin-T (TNT) and natriuretic peptide (BNP) in patients hospitalized for Covid-19. Methods: This was a convenience sample of patients hospitalized for COVID-19. Data were collected from medical records to assess the association of TnT and BNP measured in the first 24 hours of hospital admission with the combined outcome (CO) of death or need for mechanical ventilation. Univariate analysis was used to compare the groups with and without the CO. Cox's multivariate model was used to determine independent predictors of the CO. Results: We evaluated 183 patients (age = 66.8±17 years, 65.6% of which were males). The time of follow-up was 7 days (range 1 to 39 days). The CO occurred in 24% of the patients. The median troponin-T and BNP levels were 0.011 and 0.041ng/dL (p <0.001); 64 and 198 pg/dL (p <0.001), respectively, for the groups without and with the CO. In the univariate analysis, in addition to TnT and BNP, age, presence of coronary disease, oxygen saturation, lymphocytes, D-dimer, t-CRP and creatinine, were different between groups with and without outcomes. In the bootstrap multivariate analysis, only TnT (1.12 [95% CI 1.03-1.47]) and t-CRP (1.04 [95% CI 1.00-1.10]) were independent predictors of the CO. Conclusion: In the first 24h of admission, TnT, but not BNP, was an independent marker of mortality or need for invasive mechanical ventilation. This finding further reinforces the clinical importance of cardiac involvement in COVID-19. (Arq Bras Cardiol. 2020; 115(4):660-666)

https://doi.org/10.36660/abc.20200385 2767 descargas

13.

Shoulder Arthroplasty: Tenotomy of the Subscapularis Tendon versus the Lesser Tuberosity Osteotomy
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França, Flávio Oliveira

; Freitas, José Márcio Alves

; Mariosa, Carlos Alberto Menezes

; Bastiani, Carlos Eduardo

; Godinho, Glaydson Gomes

Revista Brasileira de Ortopedia

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Ago 2020, Volumen 55 Nº 4 Paginas 463 - 469

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Avaliar e comparar a função do músculo subescapular entre os grupos submetidos a tenotomia do subescapular (Grupo A) e osteotomia do tubérculo menor (Grupo B), em pacientes tratados por artroplastia anatômica total e parcial de ombros apresentando osteoartrose primária. Métodos Estudo retrospectivo de pacientes portadores de osteoartrose primária glenoumeral tratados cirurgicamente com prótese anatômica total ou parcial de ombro, avaliados por exame clínico, exames de imagens, escala visual analógica de dor e escore funcional de Constant e Murley. Foram avaliados 28 pacientes, totalizando uma amostra de 32 ombros operados. O seguimento mínimo foi de 12 meses (média 47,45 meses). Resultados Nos pacientes submetidos à tenotomia do tendão subescapular, dez obtiveram resultado ultrassonográfico com ruptura de sua espessura total (56%). A consolidação ocorreu em todos pacientes submetidos a osteotomia do tubérculo menor. Não houve diferença entre os grupos na comparação do teste Lift Off, da força nos testes Belly Press e Bear hug, e no escore de Constant e Murley. Conclusões Não encontramos diferença entre os grupos A e B na comparação do teste Lift Off, da força nos testes Belly Press e Bear hug, e no escore de Constant e Murley.

Abstract Objective To evaluate and compare subscapular muscle function among patients undergoing subscapular tenotomy (Group A) and lesser tuberosity osteotomy (Group B), in patients treated with total and partial anatomic shoulder arthroplasty for primary osteoarthrosis. Methods Retrospective study of patients with primary glenohumeral osteoarthrosis surgically undergoing total or partial anatomic shoulder prosthesis implant, evaluated by clinical examination, imaging exams, analogue pain scale and Constant and Murley functional score. A total of 28 patients were evaluated, totalizing a sample of 32 operated shoulders. The minimum follow-up was of 12 months (mean 47.45 months). Results Among patients submitted to subscapularis tendon tenotomy, 10 had an ultrasound with total rupture of its thickness (56%). All of the patients of the group B showed lesser tuberosity healing. There was no difference between groups comparing strength evaluated by Belly press and Bear hug tests as well as clinical outcome, through the Constant and Murley score. Conclusions We did not find differences between Groups A and B evidenciated by comparing strength in the Lift-off test, in the Belly press and Bear hug tests and through he Constant and Murley score.

https://doi.org/10.1055/s-0039-3402469 640 descargas

14.

Níveis Séricos do BDNF na Proteção Cardiovascular e em Resposta ao Exercício
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Trombetta, Ivani Credidio

; DeMoura, José Roberto

; Alves, Cleber Rene

; Carbonari-Brito, Renato

; Cepeda, Felipe Xerez

; Lemos Jr, José Ribeiro

Arquivos Brasileiros de Cardiologia

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Ago 2020, Volumen 115 Nº 2 Paginas 263 - 269

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo As doenças cardiovasculares (DCV) são atualmente a maior causa de morte no Brasil e no mundo. Em 2016 as DCV foram responsáveis por mais de 17 milhões de mortes, representando 31% de todas as mortes em nível global. Mecanismos moleculares e genéticos podem estar envolvidos na proteção cardiovascular e devem ser considerados nas novas abordagens terapêuticas. Nesse sentido, recentes estudos têm relatado que o Fator Neurotrófico Derivado do Encéfalo (Brain-Derived Neurotrophic Factor, BDNF) está reduzido em indivíduos predispostos a desenvolverem DCV, e que o treinamento físico aeróbio aumenta as quantidades de BDNF circulante. O BDNF é uma neurotrofina encontrada em altas concentrações no hipocampo e córtex cerebral, sendo considerada molécula-chave na manutenção da plasticidade sináptica e na sobrevivência das células neuronais. Além da plasticidade neuronal, BDNF também é importante na função vascular, promovendo angiogênese por meio da regulação por espécies reativas de oxigênio (ROS). Entretanto, uma variante do gene do BDNF em humanos, o polimorfismo Val66Met (substituição do aminoácido valina por uma metionina na posição 66 do códon), que ocorre em 20-30% da população caucasiana, pode afetar as concentrações de BDNF no plasma e sua atividade em todos os tecidos periféricos contendo receptores tirosina quinase B (TrkB), como o endotélio. De fato, recentemente observamos que o polimorfismo Val66Met prejudica a reatividade vascular e o BDNF circulante em resposta ao treinamento físico. Dessa forma, apresentaremos a seguir uma discussão sobre os níveis séricos de BDNF na proteção cardiovascular, a variante genética Val66Met na reatividade vascular e o efeito do exercício físico.

Abstract Cardiovascular disease (CVD) is currently the leading cause of death in Brazil and worldwide. In 2016, CVD accounted for more than 17 million deaths, representing 31% of all deaths globally. Molecular and genetic mechanisms may be involved in vascular protection and should be considered in new therapeutic approaches. In this sense, recent studies have reported that brain-derived neurotrophic factor (BDNF) is reduced in individuals predisposed to develop CVD, and that aerobic physical training increases the amounts of circulating BDNF. BDNF is a neurotrophin found at high concentrations in the hippocampus and cerebral cortex and is considered a key molecule for the maintenance of synaptic plasticity and survival of neuronal cells. In addition to neuronal plasticity, BDNF is also important in vascular function, promoting angiogenesis through the regulation of reactive oxygen species (ROS). However, a variant of the BDNF gene in humans, the Val66Met polymorphism (substitution of the amino acid valine for a methionine at position 66 of the codon), occurring in 20-30% of the Caucasian population, may affect plasma BDNF concentrations and its activity in all peripheral tissues containing tyrosine kinase B receptors (TrkB), such as the endothelium. Thus, we will present a discussion about the role of serum BDNF levels in cardiovascular protection, Val66Met genetic variant in vascular reactivity and the effect of physical exercise.

https://doi.org/10.36660/abc.20190368 2268 descargas

15.

BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 1): AN UPDATE ON DIAGNOSIS, STAGING, ENDOSCOPIC TREATMENT AND FOLLOW-UP
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BARCHI, Leandro Cardoso

; RAMOS, Marcus Fernando Kodama Pertille

; YAGI, Osmar Kenji

; MUCERINO, Donato Roberto

; BRESCIANI, Claudio José Caldas

; RIBEIRO JÚNIOR, Ulysses

; ANDREOLLO, Nelson Adami

; ASSUMPÇÃO, Paulo Pimentel

; WESTON, Antônio Carlos

; COLLEONI NETO, Ramiro

; ZILBERSTEIN, Bruno

; Ferraz, Álvaro Antônio Bandeira

; Charruf, Amir Zeide

; Dias, André Roncon

; Brandalise, André

; Silva, André Maciel da

; Alves, Barlon

; Malheiros, Carlos Alberto

; Marins, Carlos Augusto Martinez

; Leite, Celso Vieira

; Szor, Daniel

; Wohnrath, Durval R.

; Ilias, Elias Jirjoss

; Martins Filho, Euclides Dias

; Lopasso, Fabio Pinatel

; Coimbra, Felipe José Fernandez

; Felippe, Fernando E. Cruz

; Tomasisch, Flávio Daniel Saavedra

; Takeda, Flavio Roberto

; Ishak, Geraldo

; Laporte, Gustavo Andreazza

; Silva, Herbeth José Toledo

; Cecconello, Ivan

; Rodrigues, Joaquim José Gama

; Grande, José Carlos Del

; Lourenço, Laércio Gomes

; Motta, Leonardo Milhomem da

; Ferraz, Leonardo Rocha

; Moreira, Luis Fernando

; Lopes, Luis Roberto

; Toneto, Marcelo Garcia

; Mester, Marcelo

; Rodrigues, Marco Antônio Gonçalves

; Carvalho, Marineide Prudêncio de

; Franciss, Maurice Youssef

; Forones, Nora Manoukian

; Corletta, Oly Campos

; Castro, Osvaldo Antonio Prado

; Malafaia, Osvaldo

; Kassab, Paulo

; Savassi-Rocha, Paulo Roberto

; Oliveira, Rodrigo Jose de

; Sallun, Rubens Antonio Aissar

; Weschenfelder, Rui

; Oliveira, Saint Clair Vieira de

; Abreu, Thiago Boechat de

; Castria, Tiago Biachi de

; Barra, Williams

; Costa Júnior, Wilson Luiz da

; Freitas Júnior, Wilson Rodrigues de

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2020, Volumen 33 Nº 3 elocation e1535

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Racional: O II Consenso Brasileiro de Câncer Gástrico da Associação Brasileira de Câncer Gástrico (ABCG) foi recentemente publicado. Nesta ocasião, inúmeros especialistas que atuam no tratamento desta doença expressaram sua opinião diante declarações apresentadas. Objetivo: Apresentar as Diretrizes da ABCG (Parte 1) quanto ao diagnóstico, estadiamento, tratamento endoscópico e seguimento dos pacientes com câncer gástrico. Métodos: Para formulação destas Diretrizes os autores realizaram extensa e atual revisão referente a cada declaração presente no II Consenso, utilizando as bases Medline/PubMed, Cochrane Library e SciELO com os seguintes descritores: câncer gástrico, estadiamento, tratamento endoscópico e seguimento. Ainda, cada declaração foi classificada de acordo com o nível de evidência e grau de recomendação. Resultados: Das 24 declarações, duas (8,3%) foram classificadas com nível de evidência A, 11 (45,8%) B e 11 (45,8%) C. Quanto ao grau de recomendação, seis (25%) declarações obtiveram grau de recomendação 1, nove (37,5%) grau 2a, seis (25%) 2b e três (12,5%) 3. Conclusão: As diretrizes aqui presentes têm a finalidade de auxiliar os profissionais que atuam no combate ao câncer gástrico com informações relevantes e atuais, permitindo que sejam aplicadas na prática médica diária.

ABSTRACT Background: The II Brazilian Consensus on Gastric Cancer by the Brazilian Gastric Cancer Association (ABCG) was recently published. On this occasion, several experts in gastric cancer expressed their opinion before the statements presented. Aim: To present the ABCG Guidelines (part 1) regarding the diagnosis, staging, endoscopic treatment and follow-up of gastric cancer patients. Methods: To forge these Guidelines, the authors carried out an extensive and current review regarding each statement present in the II Consensus, using the Medline/PubMed, Cochrane Library and SciELO databases with the following descriptors: gastric cancer, staging, endoscopic treatment and follow-up. In addition, each statement was classified according to the level of evidence and degree of recommendation. Results: Of the 24 statements, two (8.3%) were classified with level of evidence A, 11 (45.8%) with B and 11 (45.8%) with C. As for the degree of recommendation, six (25%) statements obtained grade of recommendation 1, nine (37.5%) recommendation 2a, six (25%) 2b and three (12.5%) grade 3. Conclusion: The guidelines presented here are intended to assist professionals working in the fight against gastric cancer with relevant and current information, granting them to be applied in the daily medical practice.

https://doi.org/10.1590/0102-672020200003e1535 2100 descargas

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