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Abstract Background Computerized cognitive training programs may have benefited the self-assessment of memory, quality of life, and mood among older adults during the coronavirus disease 2019 (COVID-19) pandemic. Objective To determine the subjective impacts of computerized cognitive training on mood, frequency of forgetfulness, memory complaints, and quality of life in the elderly using an online platform. Methods In total, 66 elderly participants of USP 60 +, a program for the elderly offered by Universidade de São Paulo, who voluntarily enrolled in the study were selected and randomized with an allocation ratio of 1:1 into 2 groups: the training group (n = 33) and the control group (n = 33). After signing the free and informed consent form, they answered a protocol which included a sociodemographic questionnaire, the Memory Complaints Questionnaire (MAC-Q), the McNair and Kahn’s Frequency of Forgetfulness Scale, the Geriatric Depression Scale (GDS-15), the Geriatric Anxiety Inventory (GAI), and the Control, Autonomy, Self-Realization, and Pleasure (CASP-19) questionnaire. The training cognitive game platform aimed to stimulate various cognitive aspects, including memory, attention, language, executive functions (reasoning, logical thinking), and visual and spatial skills. Results The participants of the training group showed a reduction in the MAC-Q, MacNair and Kahn, and GAI scores in the pre- and posttest comparison. Significant differences were identified between the groups regarding the total scores of the MAC-Q in the post-test, which was also evidenced by the logistic regression. Conclusion Participation in a computerized cognitive intervention promoted reductions in memory complaints, frequency of forgetfulness, and anxiety symptoms, in addition to improving self-reported quality of life.

Resumo Antecedentes Programas informatizados de treinamento cognitivo podem ter beneficiado a autoavaliação da memória, a qualidade de vida e o humor entre os idosos durante a pandemia de doença do coronavírus 2019 (coronavirus disease 2019, COVID-19, em inglês). Objetivo Determinar os impactos subjetivos do treinamento cognitivo computadorizado no humor, na frequência de esquecimento, nas queixas de memória, e na qualidade de vida em idosos utilizando uma plataforma online. Métodos Ao todo, 66 idosos participantes do programa USP 60 +, oferecido à terceira idade pela Universidade de São Paulo, e inscritos voluntariamente no estudo, foram selecionados e randomizados em uma razão de 1:1 em 2 grupos: grupo treinamento (n = 33) e grupo controle (n = 33). Após assinarem o termo de consentimento livre e esclarecido, os participantes responderam a um protocolo que incluía um questionário sociodemográfico, o Questionário de Queixas de Memória (Memory Complaints Questionnaire, MAC-Q), A Escala de Frequência de Esquecimento de McNair e Kahn, a Escala de Depressão Geriátrica (Geriatric Depression Scale, GDS-15), o Inventário de Ansiedade Geriátrica (Geriatric Anxiety Inventory, GAI), e –o questionário de Controle, Autonomia, Autorrealização e Prazer (Control, Autonomy, Self-Realization, and Pleasure, CASP-19). A plataforma de jogos cognitivos de treinamento visou estimular diversos aspectos cognitivos, incluindo memória, atenção, linguagem, funções executivas (raciocínio, raciocínio lógico) e habilidades visuais e espaciais. Resultados Na comparação pré e pós-teste, os participantes do grupo de treinamento apresentaram redução nas pontuações do MAC-Q, da escala McNair e Kahn e do GAI. Diferenças significativas entre os grupos quanto às pontuações totais da escala MAC-Q no pós-teste também foram evidenciadas pela regressão logística. Conclusão A participação em uma intervenção cognitiva computadorizada promoveu reduções nas queixas de memória, frequência de esquecimento e sintomas de ansiedade, além de melhorar a qualidade de vida autorrelatada.

https://doi.org/10.1055/s-0043-1767823

Attitudes and practices in the management of attention deficit hyperactivity disorder among Brazilian pediatric neurologists who responded to a national survey: a cross-sectional study
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Nunes, Marina Estima Neiva

; Zuanetti, Patricia Aparecida

; Hamad, Ana Paula Andrade

Sao Paulo Medical Journal

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2023, Volumen 141 Nº 4 elocation e2021966

Resumen: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Attention deficit hyperactivity disorder (ADHD) has a prevalence of 5.3% among children and adolescents. It is characterized by attention deficit, hyperactivity, and impulsivity. OBJECTIVE: We aimed to conduct a survey involving pediatric neurologists in the management of ADHD and compare the results with the current literature and guidelines. DESIGN AND SETTING: Descriptive analytical study of a virtual environment, was used Test of equality of proportions for comparison between two groups of pediatric neurologists (working as specialists for > 6 versus ≤ 6 years), with a significance level of P = 0.05. METHODS: This cross-sectional study used a virtual questionnaire covering the steps in the diagnosis and treatment of children with ADHD. The inclusion criteria were professionals who had completed their residency/specialization in pediatric neurology and clinical neurologists working in pediatric neurology. RESULTS: Among the 548 electronic invitations sent, 128 were considered valid. For all participants, the diagnosis was clinically based on the disease classification manuals. Combination treatment promotes improvement of symptoms (96.9%). Among psychostimulants, short-acting methylphenidate was the most commonly prescribed medication (85.2%). Headache was the most common side effect (77.3%). Altogether, 73.4% of the participants requested laboratory tests, 71.1% requested an electrocardiogram, and 42.2% requested an electroencephalogram. Pediatric neurologists working as specialists for ≤ 6 years had more frequent referrals to psycho-pedagogists for diagnosis (P = 0.03). CONCLUSIONS: The participants complied with clinical guidelines, emphasizing the relevance of diagnostic manuals and treatment guidelines for an eminently clinical situation and enabling uniformity in quality treatment.

https://doi.org/10.1590/1516-3180.2021.0966.r1.20092022

Evaluation of the properties of WHODAS-12 measurements in individuals with Chagas disease in Brazil
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Tavares, Patrícia Aparecida

; Oliveira, Cláudia Di Lorenzo

; Ferreira, Ariela Mota

; Baldoni, Nayara Ragi

; Quintino, Nayara Dornela

; Haikal, Desiree Sant’Ana

; Bierrenbach, Ana Luiza

; Ribeiro, Antonio Luiz Pinho

; Sabino, Ester Cerdeira

; Cardoso, Clareci Silva

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volumen 65 elocation e30

Resumen: En | Texto: En | PDF: En

ABSTRACT Numerous tests employed to predict cardiac and functional status are expensive and not widely accessible for a considerable number of patients, particularly those diagnosed with Chagas disease (CD) residing in remote and endemic regions. To date, there is no knowledge of studies that have validated instruments that address functionality in an expanded way, including the biopsychosocial factors in patients with CD. This study aims to evaluate the psychometric properties of the World Health Organization Disability Assessment Schedule (WHODAS 2.0), in its 12-item shortened version (WHODAS-12) when applied to patients with CD. This is a cross-sectional study of a prospective cohort that follows individuals with CD (SaMi-Trop). Data collection took place between October 2019 and March 2020. In the interviews, sociodemographic information, life habits, clinical information, and indicators of disability measured by WHODAS-12 were collected. Descriptive analysis, internal consistency and construct validity of the instrument were performed. A total of 628 patients with CD were interviewed, most were women (69.5%), their mean age was of 57 years, and most declared an average self-perception of health (43.4%). The 12 items of WHODAS-12 were distributed into three factors, which together account for 61% of the variance. The Kaiser–Meyer–Olkin (KMO) index was 0.90, indicating adequacy of the sample for factor analysis. The internal consistency of the global scale showed alpha = 0.87. The percentage of incapacity was 16.05%, indicating mild incapacity for the evaluated patients. WHODAS-12 is a valid and reliable measure to assess the disability of the Brazilian population with CD.

https://doi.org/10.1590/s1678-9946202365030

Effect of calcium chloride and gelling agents on the physicochemical and sensory characteristics of sugar-free banana preserves
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DIAS, ANA CLARA C.

; BARBOSA, LAIS CRISTINA S.

; GUIA, MICHAEL DOUGLAS M.

; SILVEIRA, CLARA G. DA

; BARCELOS, JULIANA C.

; SANTOS, IZABELA S. DOS

; CUNHA, LUCIANA R. DA

; PEREIRA, PATRÍCIA APARECIDA P.

Anais da Academia Brasileira de Ciências

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2023, Volumen 95 Nº 1 elocation e20201480

Resumen: En | Texto: En | PDF: En

Abstract Banana preserve is produced by mixing the puree of the fruit with sucrose and organic acids. However, concerns about body esthetics or health reasons have encouraged the search for low-calorie products. Therefore, the objective of this study was to evaluate the effect of calcium chloride (CaCl2), carrageenan gum, and low methoxyl pectin (LM-pectin) on the physicochemical and sensory characteristics of sugar-free banana preserves. By using a central composite rotational design (CCRD) of 2³ + 6 axial points + 4 central points, we obtained 18 formulations that were further tested. Lower CaCl2 concentrations (0.54% to 0.61%) resulted in preserves with lower pH and more vivid color. The increased concentration of LM-pectin (1.40% to 1.64%) resulted in formulations with a yellowish-red hue and with lower moisture, thus, reducing the flavor and purchase intention of the product. Higher concentrations of carrageenan gum (1.04% to 1.15%) decreased the perception of banana preserve aroma. Therefore, concentrations of CaCl2 ranging from 0.54% to 0.61%, carrageenan gum ranging from 0.74% to 0.89% and LM-pectin ranging from 1.40% to 1.64% resulted in sugar-free banana preserves with ideal sweetness and consistency and were, therefore, more acceptable.

https://doi.org/10.1590/0001-3765202320201480

Association between food consumption and the Quality of Diet Index Adapted for pregnant women
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Gotine, Ana Raquel Ernesto Manuel

; Filgueiras, Mariana De Santis

; Ribeiro, Sarah Aparecida Vieira

; Araújo, Raquel Maria Amaral

; Pereira, Patrícia Feliciano

Revista Brasileira de Saúde Materno Infantil

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2023, Volumen 23 elocation e20210361

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objectives: to investigate the association between the Índice de Qualidade da Dieta Adaptado para Gestantes (IQDAG) (Quality of Diet Index Adapted for Pregnant Women) with food consumption, lifestyle and health information. Methods: cross-sectional study with 110 pregnant women assisted at a public health service. Sociodemographic, nutritional and health data were collected from medical records. Food consumption was investigated through the usual intake, for a nutritional analysis, DietPro® program version 6.1 was used. Quality ofdiet was assessed using the IQDAG. Multinomial logistic regression was used to investigate an association between food consumption and IQDAG. Results: the average total score of the IQDAG was 61.3 (±26.1), this is the best quality of the diet. After adjusting for age, schooling and physical activity, the highest consumption of vitamin A (OR=1.04; CI95% = 1.02-1.07) and B2 (OR=2.63; CI95% = 1.19-5.70) was associated with a greater chance of having a better quality of diet (3rdtertile of the IQDAG). Conclusions: pregnant women with better quality of diet had higher intakes of vitamins A and B2. However, other population-based studies are suggested to more broadly in verify its association with food consumption and its ability to identify adherence to nutritional recommendations.

Resumo Objetivos: investigar a associação entre o Índice de Qualidade da Dieta Adaptado para Gestantes (IQDAG) com o consumo alimentar e hábitos de vida e informações de saúde. Métodos: estudo transversal com 110 gestantes atendidas em um serviço público de saúde. Os dados sociodemográficos, nutricionais e de saúde foram coletados a partir dos prontuários de atendimento. O consumo alimentar foi investigado por meio do recordatório de ingestão habitual, para a análise nutricional foi utilizado o Programa DietPro® versão 6.1. A qualidade da dieta foi avaliada utilizando o IQDAG. A regressão logística multinomial foi usada para investigar a associação entre o consumo alimentar e IQDAG. Resultados: a média da pontuação total do IQDAG foi 61,3 (±26,1), isto é uma melhor qualidade da dieta. Após ajuste por idade, escolaridade e atividade física, o maior consumo de vitamina A (OR=1,04; IC95%= 1,02-1,07) e B2 (OR= 2,63; IC95%= 1,19-5,70) esteve associado a maior chance da gestante apresentar uma melhor qualidade da dieta (3º tercil do IQDAG). Conclusões: gestantes com melhor qualidade da dieta tiveram maior ingestão das vitaminas A e B2. Entretanto, sugere-se outros estudos de base populacional para verificar de forma mais ampla sua associação com o consumo alimentar e sua capacidade de identificar a adesão as recomendações nutricionais.

https://doi.org/10.1590/1806-9304202320210361-en

The presence of depressive symptoms and cognitive performance among older individuals with and without self-reported chronic diseases
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Silva, Thaís Bento Lima da

; Ordonez, Tiago Nascimento

; Silva, Guilherme Alves da

; Souza, Maria Antônia Antunes de

; Silva, Sabrina Aparecida da

; Santos, Gabriela dos

; Gutierrez, Beatriz Aparecida Ozello

; Moreira, Ana Paula Bagli

; Costa, Laydiane Alves

; Moraes, Luiz Carlos de

; Lessa, Patrícia Prata

; Cardoso, Neide Pereira

; Sakaguchi, Mitsuru

; Silva, Henrique Salmazo da

; Brucki, Sonia Maria Dozzi

Dementia & Neuropsychologia

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2023, Volumen 17 elocation e20230035

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT. Dementias secondary to cardiovascular diseases are the second cause of neurogenerative diseases. These conditions can be prevented by controlling risk factors, and it is necessary to observe the relationship between chronic diseases. Objective: to know the influence of chronic non-communicable diseases on cognition and depressive symptoms in the elderly, amid the COVID-19 pandemic. Methods: 578 older adults were evaluated using a sociodemographic questionnaire, the Brazilian Telephone version of the Mini Mental State Examination (Braztel-MMSE), the Geriatric Depression Scale (GDS-15) and an open questionnaire related to NCDs. Results: the association of Non-Communicable Diseases (NCD) with age, depressive symptoms and schooling was confirmed. Conclusion: no association with cognitive decline was evident due to the relationship of high schooling of participants and control of NCDs.

RESUMO. As demências secundárias às doenças cardiovasculares são a segunda causa de doenças neurodegenerativas. Essas condições podem ser prevenidas pelo controle de fatores de risco, sendo necessário observar a relação entre doenças crônicas. Objetivo: Conhecer a influência das doenças crônicas não transmissíveis (DCNT) na cognição e nos sintomas depressivos em pessoas idosas, em meio à pandemia da COVID-19. Métodos: Foram avaliados 578 idosos utilizando um questionário sociodemográfico, o Brazilian telephone version of the Mini Mental State Examination (Braztel-MMSE), a Escala de Depressão Geriátrica (GDS-15) e um questionário aberto relacionado às DCNT. Resultados: Foi confirmada a associação das DCNT crônicas com idade, sintomas depressivos e escolaridade. Conclusão: Nenhuma associação com declínio cognitivo foi evidente em razão da relação da alta escolaridade dos participantes com o controle das DCNT.

https://doi.org/10.1590/1980-5764-dn-2023-0035

Attention-Deficit Hyperactivity Disorder (ADHD) versus Specific Learning Disorder-Reading Subtype (Dyslexia): performance in writing tasks
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Zuanetti, Patrícia Aparecida

; Pontes-Fernandes, Angela Cristina

; Moraes, Náthali Maganha de

; Hamad, Ana Paula Andrade

; Fukuda, Marisa Tomoe Hebihara

Revista CEFAC

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2023, Volumen 25 Nº 6 elocation e7723

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: to analyze and compare the writing performance between students with attention-deficit/hyperactivity disorder (ADHD) and students with dyslexia. Methods: altogether, 27 children participated in the study, divided into the groups G-ADHD and G-Dyslexia. Their writing was assessed with a test that uses word and pseudoword dictation. The analysis addressed their writing level, word/pseudoword writing performance, and misspelling types. The groups were compared with the two-proportion z-test between two samples and the Mann-Whitney test (α = 0.05). Results: only one child in G-Dyslexia out of the 27 participating children was classified at the syllabic-alphabetical level. The others were classified at the alphabetical level, with no statistical difference between the groups in this item. The analysis of word/pseudoword writing performance revealed a difference between mean total scores, in which G-ADHD performed better. This group also had a higher percentage of children whose performance was classified as adequate for their age. There was a difference in misspellings between the groups in the omission of syllables, omission/addition of letters in complex syllables, and total performance - G-dyslexia made such errors more often. Conclusion: children with ADHD performed better in writing than the ones with dyslexia. However, writing cannot be used as a diagnostic marker between these conditions.

RESUMO Objetivo: analisar e comparar o desempenho em escrita entre escolares com Transtorno do Déficit de Atenção e Hiperatividade (TDAH) ou escolares com Dislexia. Métodos: participaram 27 crianças, divididas nos grupos: G-TDAH; G-Dislexia. Para avaliação da escrita, utilizou-se um teste que se baseia no ditado de palavras/pseudopalavras e foram analisados o nível de escrita, o desempenho em escrever palavras/pseudopalavras e os tipos de erros ortográficos presentes. Para comparação entre os grupos foram utilizados os testes Igualdade de Proporções entre duas amostras e Mann-Whitney (α=0,05). Resultados: das 27 crianças participantes, apenas uma do G-Dislexia foi classificada no nível silábico-alfabético. Todas as outras foram classificadas no nível alfabético, não havendo diferença estatística deste item entre os grupos. Em relação à análise do desempenho em escrever palavras/pseudopalavras, observou-se diferença entre os valores médios totais, com melhor desempenho do G-TDAH. Neste mesmo grupo, há maior porcentagem de crianças classificadas com desempenho adequado para a idade. Em relação aos erros ortográficos, houve diferença entre os grupos em omissão de sílabas, omissão/adição de letras em sílabas complexas e no desempenho total, sendo o G-dislexia com maior número destes tipos de erros. Conclusão: crianças com TDAH apresentaram melhor desempenho em escrita do que crianças com dislexia, porém, a escrita não pode ser utilizada como um marcador diagnóstico entre essas condições.

https://doi.org/10.1590/1982-0216/20232567723

“Pensar com” José Mário Pires Azanha a elaboração do porvir educacional brasileiro
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Amparo, Patrícia Aparecida do

; Lima, Ana Laura Godinho

; Catani, Denice Barbara

Estudos Avançados

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Ago 2022, Volumen 36 Nº 105 Paginas 255 - 269

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Na situação pouco esperançosa imposta pela devastação a que nos submeteu o ano 2020, a inquietação acerca dos rumos possíveis para a educação num futuro próximo nos leva a procurar modos de propor a educação que se alicercem sobre valores de cuidado com o mundo. Assim, o artigo retoma o pensamento educacional de José Mário Pires Azanha e busca “pensar com” ele possibilidades educativas no nosso tempo. Ressalta-se como as formulações e ações do autor, tecidas no interior de sua produção teórica e atividades profissionais, têm oferecido elementos estruturantes aos debates acerca da escola, do trabalho pedagógico, das relações entre professores e alunos e da pesquisa educacional. Afirma-se, por exemplo, o modo como ele antecipou o empenho para com a justiça social educativa, expressa pela universalização do acesso à escola, na história educacional paulista. Unindo pensamento e ação o autor elabora proposições científicas e políticas num modelo de investigação educacional e de constituição da pedagogia que acolhe a vida e o trabalho escolar como construções sociais, valorizando a autonomia dos professores e das escolas na elaboração do projeto político pedagógico da instituição. Concebemos assim a reflexão contida no texto como uma situação exemplar para se compreender nossos “clássicos do pensamento educacional”, tomando a ideia de clássico a partir das sugestões de Ítalo Calvino.

ABSTRACT In the hopeless situation of devastation imposed upon the world’s population in 2020, concerns about the possible directions for education soon lead us to look for different proposals for an education based on values of care for humanity. This article discusses the educational thought of José Mário Pires Azanha and examines educational possibilities, formulations and actions he proposes in his theoretical production and professional activities. Azanha brings structuring elements to the debate about schools, pedagogical work, and the relations between teachers, students and educational research, as he anticipated the pedagogical commitment to social justice expressed by the universal access to education in São Paulo’s history. Bringing together thought and action, Azanha elaborates scientific propositions and policies based on a model of educational research and constitution of pedagogy that considers life and schoolwork as social constructions, valuing the autonomy of teachers and schools in developing an institution’s political pedagogical project. Thus, this study hopes to understand our classical pedagogical thought. The idea of “classic” is taken from Italo Calvino.

https://doi.org/10.1590/s0103-4014.2022.36105.015

Caracterización de DELUX: Dispositivo de esterilización por luz ultravioleta para máscaras PFF2/N95 contra COVID-19
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Lombello, Christiane Bertachini

; Daghastanli, Nasser Ali

; Neto, Hermann Windisch

; Affonso Fonseca, Fernando Luiz

; Ambrosio, Felipe Nogueira

; Arbex, Raquel

; Fernando, Isabella Kobb

; da Silva, Victor Allisson

; dos Santos, Luisa Pataquini

; da Ana, Patricia Aparecida

Ingenius. Revista de Ciencia y Tecnología

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Jun 2022, Nº 27 Paginas 23 - 31

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The World Health Organization (WHO) has declared a public health pandemic state due to the transmission of the new coronavirus on March 11th, 2020. COVID-19, that is caused by SARS-CoV-2, has a very broad clinical spectrum, with predominantly respiratory symptoms developments. The role of the health professionals in fighting the pandemic requires the use of Personal Protective Equipment (PPE). PFF2 / N95 masks are suitable PPEs for this purpose. Due to the high demand for PFF2 / N95 masks to fight the pandemic, there was a shortage of this PPE worldwide. This work aims to present a characterization of the device called DELUX, utilized for UVC (ultraviolet C light spectra) sterilization of PFF2 / N95 masks, and allowing to extend the time of safe use of this PPE in emergency conditions. The photometric validation of the device resulted in the verification of the emission spectrum of the lamps used in the device, and the measurement of the optical power, demonstrating the adequacy of irradiation with UVC light, with a 15-minute cycle, and safely. Biological validation showed that DELUX is capable of inactivating SARS-CoV-2 present on the surface of PFF2 / N95 masks, thus being efficient for their sterilization. The safety offered by the sterilization cycle allows to extend the safe use of those masks.

Resumen La Organización Mundial de la Salud (OMS) declaró un estado pandémico de salud pública debido a la transmisión del nuevo coronavirus el 11 de marzo de 2020. La COVID-19, causada por el SARS-CoV-2, tiene un espectro clínico muy amplio, con predominio de desarrollos sintomáticos respiratorios. El papel de los profesionales de salud en la lucha contra la pandemia requiere un equipo de protección personal (EPP). Las máscaras PFF2 / N95 son EPP adecuados para este propósito. Debido a la gran demanda de máscaras PFF2 / N95 para combatir la pandemia, hubo escasez en el mercado. Este trabajo tiene como objetivo caracterizar un dispositivo denominado DELUX para la esterilización por UVC (espectros de luz ultravioleta C) de mascarillas PFF2 / N95, ampliando su tiempo de uso seguro en condiciones de emergencia. La validación fotométrica del dispositivo permitió la verificación del espectro de emisión de las lámparas empleadas en el dispositivo y la medición de la potencia óptica, demostrando la idoneidad de la irradiación con luz UVC, en ciclos de 15 minutos, de forma segura. La validación biológica mostró que DELUX es capaz de desactivar el SARS-CoV-2 presente en la superficie de las mascarillas PFF2 / N95, siendo así eficiente para su esterilización extendiendo el tiempo de utilización de estas mascarillas.

https://doi.org/10.17163/ings.n27.2022.03 25 descargas

10.

The effects of pharmacist interventions on health outcomes in patients with advanced prostate cancer in Brazil
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Aguiar, Patricia M

; Mori, Ana Luiza PM

; Lima, Maria GF de

; Rossi, Magali SPN

; Nicoletti, Maria Aparecida

; Martins, Karina OF

; Lopes, Ana Lúcia M

; Coan, Teresa Cristina M

; Fugita, Oscar Eduardo H

; Storpirtis, Sílvia

Brazilian Journal of Pharmaceutical Sciences

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2022, Volumen 58 elocation e19273

Resumen: En | Texto: En | PDF: En

Abstract This study examined the effects of pharmacist interventions for patients with advanced prostate cancer. A pre-post study was conducted between October 2014 and August 2017 in a community pharmacy in Brazil for outpatients with advanced prostate cancer, aged ≥ 18 years, using cyproterone acetate and/or goserelin. The patients had face-to-face meetings with a pharmacist who dispensed antiandrogenic drugs and performed interventions aimed at solving and/or preventing drug-therapy problems. Primary outcomes regarding prostate-specific antigen (PSA) and testosterone levels were compared at 0, 6, and 12 months, whereas secondary outcomes-medication adherence and quality of life-were compared at baseline and at the 12-month follow-up. Medication adherence was assessed using the Morisky-Green test, and quality of life was measured by the Medical Outcomes Study 36-item Short Form (SF-36) and the Functional Assessment of Cancer Therapy-Prostate (FACT-P). The analysis included 20 patients; 311 drug-therapy problems were identified and most of them were related to adverse reactions (78.5%). The most common adverse reactions were reduced libido, erectile dysfunction, hyperglycemia, fatigue, and gynecomastia. Testosterone levels significantly decreased at 6 months, and PSA levels at 6 and 12 months. No significant changes in adherence were noted at the end of the study. A significant increase in the “pain” domain and an improvement trend in the “physical aspects” and “vitality” domains were observed based on the SF-36 instrument. The findings show that pharmacist interventions were able to improve PSA and testosterone levels, and some domains of quality of life of patients.

https://doi.org/10.1590/s2175-97902021000219273

11.

Factors associated with hospitalizations for Covid-19 in patients with rheumatoid arthritis: data from the Reumacov Brazil registry
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Gomides, Ana Paula Monteiro

; Albuquerque, Cleandro Pires de

; Mota, Licia Maria Henrique da

; Devidé, Guilherme

; Dias, Laiza Hombre

; Duarte, Angela Luzia Branco Pinto

; Giovelli, Raquel Altoé

; Karnopp, Thais Evelyn

; Lima, Hugo Deleon de

; Marinho, Adriana

; Oliveira, Marianne Schrader de

; Omura, Felipe

; Ranzolin, Aline

; Resende, Gustavo

; Ribeiro, Francinne Machado

; Ribeiro, Sandra Lúcia Euzébio

; Sacilotto, Nathália de Carvalho

; Santos, Wander Gonzaga dos

; Shinjo, Samuel Katsuyuki

; Studart, Samia Araujo de Sousa

; Teixeira, Flávia Patricia Sena

; Yazbek, Michel Alexandre

; Ferreira, Gilda Aparecida

; Monticielo, Odirlei A.

; Paiva, Eduardo

; Pileggi, Gecilmara Cristina Salviato

; Reis Neto, Edgard Torres dos

; Pinheiro, Marcelo de Medeiros

; Marques, Claudia D. L.

Advances in Rheumatology

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2022, Volumen 62 elocation 13

Resumen: En | Texto: En | PDF: En

Abstract Background: Patients using immunosuppressive drugs may have unfavorable results after infections. However, there is a lack of information regarding COVID 19 in these patients, especially in patients with rheumatoid arthritis (RA). Therefore, the aim of this study was to evaluate the risk factors associated with COVID 19 hospitalizations in patients with RA. Methods: This multicenter, prospective cohort study is within the ReumaCoV Brazil registry and included 489 patients with RA. In this context, 269 patients who tested positive for COVID 19 were compared to 220 patients who tested negative for COVID 19 (control group). All patient data were collected from the Research Electronic Data Capture database. Results: The participants were predominantly female (90.6%) with a mean age of 53 ±12 years. Of the patients with COVID 19, 54 (20.1%) required hospitalization. After multiple adjustments, the final regression model showed that heart disease (OR =4.61, 95% CI 1.06–20.02. P < 0.001) and current use of glucocorticoids (OR =20.66, 95% CI 3.09–138. P < 0.002) were the risk factors associated with hospitalization. In addition, anosmia was associated with a lower chance of hospitalization (OR =0.26; 95% CI 0.10–0.67, P < 0.005). Conclusion: Our results demonstrated that heart disease and the use of glucocorticoids were associated with a higher number of hospital admissions for COVID 19 in patients with RA. Trial registration: Brazilian Registry of Clinical Trials RBR 33YTQC.

https://doi.org/10.1186/s42358-022-00244-5

12.

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Nunes, Marina Estima Neiva

; Zuanetti, Patricia Aparecida

; Hamad, Ana Paula Andrade

Sao Paulo Medical Journal

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2022, Nº ahead

Resumen: En | Texto: En | PDF: En

https://doi.org/10.1590/1516-3180.2021.0966.r1.20092022

13.

SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
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Pereira, Maria Fernanda Bádue

; Suguita, Priscila

; Litvinov, Nadia

; Farhat, Sylvia Costa Lima

; Paula, Camila Sanson Yoshino de

; Lázari, Carolina dos Santos

; Bedê, Pedro Vale

; Framil, Juliana Valeria de Souza

; Bueno, Catarina

; Branas, Priscila Cristina Abduch Adas

; Guimarães, Irina Monteiro da Costa

; Leite, Marcia Marques

; Navega, Ana Carolina Barsaglini

; Nanbu, Danilo Yamamoto

; Schvartsman, Claudio

; Pinho, João Renato Rebello

; Silva, Clovis Artur Almeida

; Marques, Heloisa Helena de Sousa

; Eisencraft, Adriana Pasmanik

; Rossi Jr, Alfio

; Delgado, Artur Figueiredo

; Leal, Gabriela Nunes

; Gibelli, Maria Augusta Cicaroni

; Palmeira, Patricia

; Sakita, Neusa Keico

; Santos, Emilly Henrique dos

; Rocha, Mussya Cisotto

; Kanunfre, Kelly Aparecida

; Okay, Thelma Suely

; Carneiro-Sampaio, Magda

; Carvalho, Werther Brunow de

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volumen 64 elocation e34

Resumen: En | Texto: En | PDF: En

ABSTRACT This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.

https://doi.org/10.1590/s1678-9946202264034

14.

Caracterização tecnológica da farinha de grão-de-bico variedade BRS cristalino
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Fernandes, Thaynnara Cristina Rodrigues

; Camargos, Luiz Fernando de

; Camilo, Patrícia Aparecida

; Jesus, Flávio Gonçalves de

; Siqueira, Ana Paula Silva

Brazilian Journal of Food Technology

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2022, Volumen 25 elocation e2021082

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The chickpea is an oilseed of high commercial importance and its cultivation was adapted to the conditions of the Brazilian Cerrado. Therefore, studies involving these adapted varieties are necessary, such as BRS Cristalino, in order to enable greater insertion and expansion in this biome. This study evaluated the physicochemical composition and technological characteristics of the raw and naturally dried grains, after being ground and refined. The evaluations carried out were associated with moisture, fixed mineral residue, lipids, protein, total fibers, carbohydrates and energy value. The ability to absorb water, oil and milk and also gelling properties were analyzed as possibly interesting properties for industrialization processes. This composition was similar to the flour of other oilseeds with protein content close to 16%, mineral residue of 2%, carbohydrates of 61% and total fibers of 10%. The technological indexes showed relevant affinity for water and milk and also good gelation capacity. According to these results, preparations with chickpea flour as an ingredient in food products are motivated.

Resumo O grão-de-bico é uma oleaginosa de elevada importância comercial e seu cultivo tem sido adaptado para as condições do Cerrado brasileiro. Diante disso, é necessário realizar pesquisas que envolvam essas espécies adaptadas, como o BRS Cristalino, para possibilitar uma maior inserção e expansão neste bioma. Este estudo avaliou características de composição físico-química e tecnológicas do grão cru e seco naturalmente, moído e refinado (farinha). As avalições realizadas foram de umidade, resíduo mineral fixo, lipídeos, proteína, fibras totais, carboidratos e valor energético. A capacidade de absorver água, óleo e leite, e as propriedades gelificantes foram analisadas como propriedades possivelmente interessantes para processos de industrialização. A farinha de grão-de-bico apresentou composição semelhante à da farinha de outras oleaginosas, com teor proteico próximo a 16%, teor de carboidrato de 61% e fibra total de 10%. Os índices tecnológicos demonstraram afinidade maior com água e leite, e boa capacidade de gelificação. A partir desses resultados, preparações com farinha de grão-de-bico como ingrediente em produtos alimentícios são motivadas.

https://doi.org/10.1590/1981-6723.08221

15.

Optimization of texture profile analysis parameters for commercial guava preserve
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Vieira, Mariele Antunes

; Schiass, Maria Cecília Evangelista Vasconcelos

; Dias, Ana Clara Costa

; Curi, Paula Nogueira

; Pereira, Patrícia Aparecida Pimenta

; Carneiro, João De Deus Souza

; Borges, Soraia Vilela

; Queiroz, Fabiana

Revista Ceres

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Dic 2021, Volumen 68 Nº 6 Paginas 530 - 538

Resumen: En | Texto: En | PDF: En

ABSTRACT Motivated by the lack of studies that standardize and optimize the parameters of texture tests, this study aimed to determine the operating conditions for TPA to maximize the discrimination among samples of fruit preserves. The texture of the commercial guava preserves was evaluated using a texturometer. The Design Central Composite Rotational (DCCR) method was applied with four independent variables: speed test, sample volume, time between compression cycles and compression percentage. Only the compression percentage and test speed were significantly influenced by the texture parameters evaluated. The optimum operating region of TPA to better discriminate differences in texture parameters depended on the variable to be optimized, and for adhesiveness a compression of 75% and a compression speed of 0.23 mm·s are recommended. To detect differences among the samples for the parameters of cohesiveness, gumminess and resilience, the use of 15% compression and 2.59 mm·s speed is suggested. In both cases, one must employ the shortest time between two cycles and use a smaller sample size to save both the time of analysis and of the sample, respectively. For the parameters of hardness, elasticity and chewiness, optimal regions were not identified.

https://doi.org/10.1590/0034-737x202168060004

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