ABSTRACT: Purple-fleshed sweet potato is a tuber rich in anthocyanins, which are phenolic pigments that confer color and present bioactive capacity. Moreover, its incorporation into dairy products can bring technological and functional benefits. Thus, this article evaluated the impact of the addition of lyophilized purple-fleshed sweet potato powder- LP (0% - Control, 2%, and 4%) on the physical, chemical, and technological characteristics of Greek yogurt. LP showed in vitro antioxidant and bioactive capacity by DPPH (20.64 ± 1.61 μmol TE g-1), FRAP (112.93 ± 4.38 μmol TE g-1), total phenolic content (103.66 ± 3.35 mg GAE g-1), and total anthocyanin content (51.10 ± 1.87 mg cyanidin 3-glucoside 100 g-1). Additionally, the assays demonstrated that the LP has 16.82 ± 0.63% of resistant starch. The fortification of Greek yogurt with LP reduced the syneresis, indicating that LP increased the water retention capacity. LP also inhibited the post-acidification process, increasing apparent viscosity, hardness, and gumminess, and promoting a stable pink coloration throughout the storage (P < 0.05). At the 4% level, the yogurt was firmer and showed greater chewiness, which is highly desirable for Greek yogurt. Therefore, the results suggested that lyophilized purple-fleshed sweet potato powder is a potential multifunctional natural ingredient.

RESUMO: Batata-doce de polpa roxa é um tubérculo rico em antocianinas, as quais são pigmentos fenólicos que conferem cor e apresentam capacidade bioativa. Além disso, sua incorporação em produtos lácteos pode trazer benefícios tecnológicos e funcionais. Desta forma, este estudo teve como objetivo avaliar o impacto da adição de pó liofilizado de batata-doce de polpa roxa - LP (0% - Controle, 2% e 4%) nas características físicas, químicas e tecnológicas de iogurte tipo Grego. LP apresentou capacidade antioxidante e bioativa in vitro para DPPH (20.64 ± 1.61 μmol TE g-1), FRAP (112.93 ± 4.38 μmol TE g-1), teor de compostos fenólicos totais (103.66 ± 3.35 mg GAE g-1) e teor de antocianinas totais (51.10 ± 1.87 mg cyanidin 3-glucoside 100 g-1). Adicionalmente, os ensaios demonstraram que o LP possui 16,82 ± 0,63% de amido resistente. A fortificação do iogurte Grego com LP reduziu a sinérese, indicando que LP aumentou a capacidade de retenção de água, LP também inibiu o processo pós-acidificação, aumentando a viscosidade aparente, a dureza e a gomosidade, e promovendo uma coloração rosa estável durante todo o armazenamento (P < 0,05). No nível de 4%, o iogurte apresentou-se mais firme e com maior mastigabilidade, o que é altamente desejável para o iogurte tipo Grego. Assim, os resultados sugerem que o pó liofilizado de batata-doce de polpa roxa é um potencial ingrediente natural multifuncional.

Resumen El objetivo del presente estudio fue investigar el uso de preparaciones homeopáticas para reducir los efectos nocivos causados por los residuos de herbicidas de auxina en la germinación de semillas y el desarrollo temprano de plántulas de pepino. El diseño estadístico fue completamente al azar (DIC) en un esquema factorial 3x5+2, con cuatro repeticiones. Los tratamientos fueron la combinación de tres preparados homeopáticos (Nux vomica, Carbo vegetabilis y Arsenicum album), en cinco dinamizaciones centesimales (6CH; 12CH; 18CH; 24CH y 30CH), más dos testigos (T0= agua destilada y TH= herbicida (Artys™) sin tratamiento homeopático). Cada unidad experimental consistió en cajas de acrílico transparente (Gerbox™) con 25 semillas de pepino, distribuidas en dos hojas de papel para germinación y humedecidas con tratamientos homeopáticos. Las unidades experimentales se mantuvieron en cámara de germinación DBO (ambiente controlado a 25 ºC y 12 h luz). Al décimo día después de la instalación del experimento se evaluaron las siguientes variables: porcentaje de germinación, longitud de brotes, longitud de raíces, fitointoxicación, porcentaje de plántulas muertas y masa seca total. El tratamiento homeopático de semillas de pepino contaminadas con herbicida picloram + 2,4-D (Artys™) provoca cambios positivos, provocando efectos interesantes en la germinación de las semillas, pero no es eficiente para la neutralización total del efecto causado por el herbicida picloram + 2,4-D y desarrollo de plántulas tempranas de pepino. Sin embargo, para algunas variables los resultados no son concluyentes con los preparados (Nux vomica, Carbo vegetabilis y Arsenicum album) y sus ultradiluciones (6CH, 12CH, 18CH, 24CH y 30CH), requiriendo más investigación para evaluar y describir la complejidad de propiedades inherente al tratamiento homeopático.

Abstract The aim of the present study was to investigate the use of homeopathic preparations to reduce the harmful effects caused by auxin herbicide residues on seed germination and early development of cucumber seedlings. The statistical design was completely randomized (DIC) in a 3x5+2 factorial scheme, with four replications. The treatments were the combination of three homeopathic preparations (Nux vomica, Carbo vegetabilis and Arsenicum album), in five centesimal dynamizations (6CH; 12CH; 18CH; 24CH and 30CH), plus two controls (T0= distilled water and TH = herbicide (Artys™) without homeopathic treatment). Each experimental unit consisted of transparent acrylic boxes (Gerbox™) with 25 cucumber seeds, distributed over two sheets of paper for germination and moistened with homeopathic treatments. The experimental units were kept in a BOD germination chamber (in a controlled environment at 25 ºC and 12 ho of light). On the tenth day after the installation of the experiment, the following variables were evaluated: percentage of germination, shoot length, root length, phytointoxication, percentage of dead seedlings and total dry mass. The homeopathic treatment of cucumber seeds contaminated with picloram + 2,4-D herbicide (Artys™) causes positive changes, causing interesting effects on seed germination, but it is not efficient for the total neutralization of the effect caused by the herbicide 2 picloram + 2,4-D and development of early cucumber seedlings. However, for some variables, the results are inconclusive with the preparations (Nux vomica, Carbo vegetabilis and Arsenicum album), and their ultradilutions (6CH, 12CH, 18CH, 24CH and 30CH), requiring more research to evaluate and describe the complexity of properties inherent to homeopathic treatment.

Resumen Objetivo: describir los efectos de la neuromodulación en el desempeño de funciones ejecutivas en pacientes con sobrepeso y/o obesidad. Métodos: se seleccionaron artículos publicados en las bases de datos PubMed, ScienceDirect, BIREME y Web of Science utilizando la siguiente combinación de descriptores: (“resolución de problemas” O “función ejecutiva” O memoria) Y (tDCS O TMS) Y obesidad. Después de aplicar los criterios de selección, 08 artículos fueron incluidos para el análisis. Resultados: los artículos incluidos tuvieron un promedio de 30,1 participantes por estudio, con un mínimo de 12 y un máximo de 76. El estado nutricional general osciló entre bajo peso y obesidad grado 3, y el índice de masa corporal promedio general fue de 28,1 kg/m2. En cuanto a los instrumentos utilizados para evaluar las funciones ejecutivas, los más frecuentes fueron: paradigma del flanqueador; rivalidad binocular para la supresión continua de flash (bCFS/NoCFS); tarea de Stroop; Tarea Go/No-Go; y tarea N-back. Los resultados primarios dependieron del sitio objetivo de la neuromodulación. Se observó una reducción del antojo de alimentos y un mejor rendimiento en el grupo activo debido a la disminución del tiempo de respuesta y al aumento de la precisión en las tareas cognitivas. Conclusión: la neuromodulación puede generar cambios en las funciones ejecutivas, reduciendo el antojo de alimentos en personas con sobrepeso y obesidad.

Abstract Objective: to describe the effects of neuromodulation on the performance of executive functions in overweight and/or individuals with obesity. Methods: articles published in PubMed, ScienceDirect, BIREME, and Web of Science databases were selected using the following combination of descriptors: (“problem solving” OR “executive function” OR memory) AND (tDCS OR TMS) AND obesity. After applying the selection criteria, 08 articles were included for analysis. Results: the articles included had an average of 30.1 participants per study, with a minimum of 12 and a maximum of 76. The overall nutritional status ranged from underweight to grade 3 obesity, and the general mean body mass index was 28,1 kg/m2. Regarding the instruments used to assess executive functions, the most frequent were: the flanker paradigm; binocular rivalry for Continuous Flash Suppression (bCFS/NoCFS); Stroop task; Go/No-Go task; and N-back task. The primary outcomes were dependent on the neuromodulation target site. Reduced food craving and improved performance in the active group were observed from decreased response time and increased precision in cognitive tasks. Conclusion: neuromodulation can generate changes in executive functions, reducing food cravings in overweight and individuals with obesity.

Resumo Objetivos explorar as demandas das mulheres, bem como do público em geral, para melhorar a qualidade da assistência obstétrica; discutir as mudanças potenciais sugeridas pelos respondentes para tal prática assistencial. Método pesquisa multicêntrica realizada por meio da plataforma Opinio, explorando opiniões dos participantes de três cidades da região Sudeste do Brasil. Tratamento dos dados por estatística descritiva e análise temática. Resultados respondentes (n=414) na faixa etária 33-37 anos (26%), incluindo mulheres (75%) com mais de 15 anos de escolaridade, casadas (45%) e com um filho (35%), revelaram lacuna de conhecimentos sobre a violência obstétrica e os direitos da mulher. Jornal, rádio e televisão são as principais fontes de informação. O enfrentamento da violência obstétrica dar-se-ia por apoio familiar. Para a práxis renovada sugeriu-se a educação coletiva sobre direitos aos cuidados obstétricos (53,1%) e o atendimento humanizado (38,2%) mobilizando o poder profissional para consolidar a humanização. Temas analíticos centrais incluíram situação vivenciada pelas mulheres e contexto idealizado de prática. Conclusão e Implicações para a prática o debate incrementa a humanização e a governança compartilhada. Recomendações propostas para advocacy coadunam com a perspectiva global da promoção de saúde das mulheres e liderança social.

Abstract Objectives Explore women’s and the general public’s demands to improve the quality of obstetric care. Discuss respondents’ suggestions to improve obstetric care, and propose recommendations for nursing advocacy in matters of obstetric violence. Method A multi-site online survey (in three cities in Brazil’s southeastern region) hosted by Opinio platform exploring the respondents’ opinions. Data was analyzed by descriptive statistics and thematic analysis. Results Respondents (n=414) aged 33-37 years (26%), including women (75%) with more than 15 years of schooling, who are married (45%) and with one child (35%), demonstrated a knowledge gap on obstetric violence and women’s rights. Newspapers, radio, and television were cited as the main sources of information. Family support was a suggested strategy to deal with obstetric violence. For the renewed praxis, collective education on obstetric care rights (53.1%) and humanized care (38.2%) were suggested to mobilize professional power to consolidate humanization in care. Central analytical themes included situations faced by women and an idealized context of practice. Conclusion and implications for practice Discussion in organizations increases humanization and shared governance. Recommendations proposed for advocacy are consistent with the global perspective of women’s health promotion and social leadership.

Resumen Objetivos explorar las demandas de las mujeres, así como del público en general, para mejorar la calidad de la atención obstétrica; Discutir los posibles cambios sugeridos por los encuestados para esta práctica de cuidado y, Proponer recomendaciones para la promoción por la enfermera en cuestiones de violencia obstétrica. Método investigación multicéntrica realizada a través de la plataforma Opinio, explorando las opiniones de los participantes de tres ciudades en el sureste de Brasil. Tratamiento de datos mediante estadísticas descriptivas y análisis temáticos. Resultados demandados (n-414) de 33 a 37 años (26%) incluyendo mujeres (75%) con más de 15 años de escolarización, casado (45%) y con un niño (35%) reveló una brecha de conocimiento sobre la violencia obstétrica y los derechos de las mujeres. El periódico, la radio y la televisión son las principales fuentes de información. La confrontación se basaría en el apoyo de la familia. Para la renovada praxis, se sugirió la educación colectiva sobre los derechos de atención obstétrica (53,1%) y la atención humanizada (38,2%) movilizar el poder profesional para consolidar la humanización. Los temas analíticos centrales incluyeron una situación experimentada por las mujeres y un contexto idealizado de práctica. Conclusión e implicaciones para la práctica el debate aumenta la humanización y la gobernanza compartida. Las recomendaciones propuestas para la promoción son coherentes con la perspectiva mundial de la promoción de la salud y el liderazgo social de las mujeres.

ABSTRACT The objective of this review was to investigate the effect of vitamin D3 supplementation on serum 25-hydroxyvitamin D concentration in individuals with single-nucleotide polymorphisms in the vitamin D receptor gene. The research was conducted on 241 articles found in the PubMed, Scopus, Science Direct, and Cochrane Library databases between November and December 2018. After article screening, three randomized double-blind placebo-controlled clinical trials were identified as eligible for this review. Participants were Australian, Brazilian, and Chinese individuals, who ingested doses of vitamin D3 ranging from 2000 IU to a megadose of 200,000 IU. The presence of the BB/Bb genotype of the BsmI polymorphism and the FokI G allele caused an increase in the serum concentrations of vitamin D after supplementation. Nonetheless, the few studies on this subject are not unanimous in their results. It is possible that differences among populations, sample sizes, doses, and time of supplementation have an impact on data and outcomes.

RESUMEN El objetivo de esta revisión fue investigar el efecto de la suplementación con vitamina D3 sobre la concentración sérica de 25-hidroxivitamina D en individuos con los polimorfismos de un solo nucleótido en el gen del receptor de la vitamina D. La investigación se realizó en 241 artículos encontrados en las bases de datos PubMed, Scopus, Science Direct y Cochrane Library entre noviembre y diciembre de 2018. Después de la selección del artículo, se identificaron tres ensayos clínicos aleatorios, controlados con placebo, doble ciego, como elegibles para esta revisión. Los participantes fueron australianos, brasileños y chinos, quienes ingirieron dosis de vitamina D3 que iban desde las 2000 UI hasta una megadosis de 200,000 UI. La presencia del genotipo BB / Bb del polimorfismo BsmI y el alelo FokI G causó un aumento en las concentraciones séricas de vitamina D después de la suplementación. No obstante, los pocos estudios sobre este tema no son unánimes en sus resultados. Es posible que las diferencias entre poblaciones, tamaños de muestra, dosis y tiempo de suplementación tengan un impacto en los datos y resultados de la investigación.

Resumo Este trabalho visou a desenvolver um método alternativo para o armazenamento pós-colheita de mamão (Carica papaya L.), var. “Tainung 1”, e controlar as principais doenças nesta fase. Foram avaliadas duas condições de armazenamento (temperatura ambiente e câmara fria); seis tratamentos (Controle, Samurai 40 mL/20l de água, Serenade® 40mL/20l de água, Fungicida EUPROOFF® 10mL/20l de água, EUPROOFF® + Serenade® + Samurai, Serenade® + Samurai); cinco períodos de armazenamento (0;3; 6; 9 e 12 dias) e três meses (dezembro, janeiro e fevereiro). A perda de massa dos frutos (PMF), a cor, o número e o tamanho das lesões foram avaliados e utilizados para calcular a incidência da doença bem como a média desta incidência. A PMF e a cor dos frutos foram mais afetadas pela variação mensal do que os tratamentos, principalmente o Samurai. O crescimento da incidência da doença foi mais lento em câmara fria. Entre os tratamentos, o Samurai foi o mais eficaz de todos; mas, se misturado a outros produtos, sua eficiência não foi observada. Esses resultados sugerem que o uso do Samurai somente em condições de câmara fria pode ser mais eficaz no controle de doenças pós-colheita do mamão.

Abstract This study aimed to establish an alternative treatment for post-harvest storage of Papaya (Carica papaya L.), var “Tainung 1” and to control major diseases at this stage. Two storage place were evaluated (room temperature and cold room); Six treatments (Control, Samurai 40ml/20l water, Serenade® 40ml/20l water, Sanatizer EUPROOFF® 10ml/20l water, EUPROOFF® + Serenade® + Samurai, Serenade® + Samurai), five storage periods (0, 3, 6, 9 and 12 days) and three seasons (December, January and February). Fruit weight loss (FWL), color index, number and size of lesions were evaluated and used to calculate the disease incidence and average of disease incidence. The FWL and index color of fruits were more affected by monthly variation than the treatments, especially the Samurai one. The growth of disease incidence were slower under cold room. Among the treatments, the Samurai was the most efficient,but if mixed to others products their efficiency was not observed. These results suggest that the using of Samurai only in cold room conditions can be more effective in control of post-harvest diseases of papaya.

Abstract Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate the association between hypertension and vitamin D receptor (Fok I) gene polymorphism. A literature search was performed according to the PRISMA guidelines using the MEDLINE®/PubMed, Scopus, Cochrane Library CENTRAL, SciELO, and LILACS databases. The quality of case-control or cohort studies and studies based on cross-sectional methodology was evaluated using the Newcastle-Ottawa Scale and the protocol of Loney and coauthors [25], respectively. In this systematic literature search, 215 publications were identified, of which 10 were analyzed, including seven case-control studies, two cross-sectional studies, and one cohort study. The association between Fok I polymorphism and hypertension was reported in 60% of the publications and the risk for hypertension was shown to be related to FF and ff genotypes. In addition, Fok I polymorphism was shown to increase plasma renin activity, which plays an important role in regulating blood pressure. However, no association was observed between Fok I polymorphism and serum vitamin D levels. In conclusion, Fok I polymorphism plays an important role in hypertension.

Abstract Introduction: much evidence confirms that vitamin D may be associated with an improvement in CD4 cell counts in HIV-infected individuals, where antiretroviral therapy (ART) is used and associated with decreased 25(OH)D levels. Objective: to carry out a systematic review on the effect of vitamin D supplementation on HIV-infected adult patients. Methods: the research was conducted in the databases Science Direct, PubMed, BVS, Scielo Cochrane and Periods, from February to April 2018, with publication limit from 2000 to 2018, without restriction of gender, ethnicity and involving individuals with age older than 18 years. To evaluate the quality of the studies, we used the protocol Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) and the Jadad scale. Results: the search initially resulted in 198 articles. After the selection process 5 articles were identified as eligible, where they highlight that vitamin D supplementation may be an associated and effective intervention to reduce hypovitaminosis. ART reduces vitamin D3 levels and changes its metabolism, being associated with the risk of mortality. However, adequate levels of 25(OH)D are positively associated with the number of CD4 + cells and the reduction of infection levels. Conclusion: vitamin D supplementation promotes immune recovery. However, the cases analysed were few, insufficient to fully confirm the benefits and recommend supplementation. Therefore, intervention studies are needed to elucidate the role of vitamin D in human protection against HIV infections.

Resumen Introducción: muchas evidencias ratifican que la vitamina D puede estar asociada con la mejora de los niveles de células CD4 en individuos infectados por el VIH, tratados con terapia antirretroviral (ART) que se asocia a la disminución de los niveles de 25(OH)D. Objetivo: realizar una revisión sistemática sobre el efecto de la suplementación de vitamina D en pacientes adultos infectados con VIH. Métodos: la investigación fue realizada en las bases de datos Science Direct, PubMed, BVS, Scielo Cochrane y periódicos, de febrero a abril de 2018, con límite de publicación de 2000 a 2018, sin restricción de género, etnicidad y que involucra a individuos con edad mayores de 18 años. Para la evaluación de la calidad de los estudios, se utilizó el protocolo Preferred Reporting Items for Systematic Reviews y Meta-Analyzes (PRISMA) y la escala de Jadad. Resultados: la encuesta inicialmente resultó en 198 artículos. Después del proceso de selección, 5 artículos fueron identificados como elegibles, donde ponen de manifiesto que la suplementación con vitamina D puede ser una intervención asociada y eficaz para reducir la hipovitaminosis. La ART reduce niveles de la vitamina D3 y altera su metabolismo, estando asociada al riesgo de mortalidad. Sin embargo, los niveles adecuados de 25(OH)D están asociados positivamente al número de células CD4 + y la reducción de los niveles de infecciones. Conclusión: la suplementación de vitamina D promueve la recuperación inmunológica. Sin embargo, los casos analizados fueron pocos, insuficientes para confirmar totalmente los beneficios y recomendar la suplementación. Por lo tanto, estudios de intervención son necesarios para elucidar la actuación de la vitamina D en la protección humana contra las infecciones por el VIH.

Resumo Este estudo objetiva compreender os aspectos relacionais de uma criança com autismo na relação com outras crianças em situações de brincadeiras. Trata‐se de uma pesquisa qualitativa do tipo estudo de caso. Os sujeitos foram 17 alunos, de três a seis anos, dez de um Centro de Educação Infantil, seis com autismo e uma com síndrome de Down. A coleta de dados foi feita por meio da observação participante, videogravação dos atendimentos e registros em diário de campo. A pesquisa permite constatar que o trabalho desenvolvido em ambiente social inclusivo, potencializado pela ação mediadora dos adultos e colegas mais experientes, favorece que as crianças com autismo apresentem atitudes que apontam sua predisposição para compartilhar brincadeiras com os colegas.

Abstract The work aims at understanding the relational aspects of a child with autism regarding other children when playing fun activities. It is about a qualitative study case typed research. The subjects were 17 students, from three to six years old having ten children belonging to a Children Education Center, six with autism and one with Down syndrome. Data collection was carried out through participant observation, service video recording and field diary records. The research allows to determine that the work developed in a social inclusive environment, strengthened by the most experienced adults and colleagues mediating action, favors the autistic children present attitudes that point out their predisposition to share fun activities with friends.

Resumen Este estudio tiene como objetivo comprender los aspectos relacionales del niño con autismo en la relación con otros niños en situaciones de juego. Se trata de una investigación cualitativa del tipo de estudio de caso. Los individuos fueron 17 alumnos, con edades de 3 a 6 años: diez de un centro de educación infantil, seis con autismo y uno con síndrome de Down. La recopilación de datos fue feita por medio de la observación participante, el servicio de grabación de vídeo y los registros en un diario de campo. La investigación permite constatar que el trabajo desarrollado en un entorno social inclusivo, potenciado por la acción mediadora de los adultos y colegas con mayor experiencia, favorece el hecho de que los niños con autismo presenten actitudes que apunten su predisposición a compartir juegos con los colegas.

Abstract This study aims to analyze the woman, caregiver of disabled people, according to gender category, from a project of teaching/research/extension in the field of Physical Education. The subjects of research were seven mothers of young people and adults with intellectual disabilities who participate in theextension project "Caregivers who dance". This qualitative-nature work used as instrument for collecting data the semi-structured interview with interpretations based on content analysis. We concluded that mothers caregivers are in this place because of a cultural-historic construction and that there is an overload of work allocated to female figures who lack the development of equitable public policies for caring work between the State and the family.

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RESUMO Objetivou-se avaliar o consumo de matéria seca (CMS), nutrientes e a análise económica de tourinhos F1 do cruzamento de Nelore com Guzerá em pastagens de Urochloa brizantha cv. Marandu em sistemas silvipastoris compostos por palmeiras de babaçu (Attalea speciosa) e em monocultivo na região Pré-Amazônica Maranhense. Os animais foram avaliados em quatro sistemas, sendo 0, 80, 131, 160 palmeiras ha-1, caracterizando monocultura (MC), baixa densidade de palmeiras (BDP), média densidade de palmeiras (MDP) e alta densidade de palmeiras (ADP) durante os períodos chuvoso (PC) e seco (PS). O consumo de MS expresso em g dia-1, %PV e g kg-0,75 foram influenciados pelas densidades de palmeiras de babaçu (P<0,05). Em ambos os períodos de avaliação, os animais mantidos no sistema de monocultura consumiram mais forragem. Os animais mantidos no sistema de ADP consumiram maiores quantidade de PB em ambos os períodos de avaliação, cerca de 478,20 e 599,18 g dia-1 para o PS e PC, respectivamente. O consumo de FDN foi influenciado pelos períodos e densidades de palmeiras (P<0,05). Observaram-se maiores CFDN para os animais mantidos na MC, em ambos os períodos. Dos quatro sistemas avaliados, somente o BDP apresentou uma receita por hectare maior que os custos, tornado assim o único sistema lucrativo, porém em uma simulação para cinco anos, todos os sistemas apresentaram um valor de Taxa Interna de Retorno superior a 6,87% da taxa de atratividade, e o sistema de BD apresentou melhor resultado comparativamente aos demais. Todos os sistemas analisados tiveram a relação Benefício/custo maior que um, ou seja, todos são viáveis economicamente.

SUMMARY This study evaluated the intake of dry matter (IDM), nutrients and the economic analysis of F1 young bulls from the cross between Nellore and Guzera on pastures of Urochloa brizantha cv. Marandu in silvopastoral systems composed of babassu palm (Attalea speciosa) and Marandu monoculture in the Pre-Amazon region of the state of Maranhão. Animals were evaluated in four systems consisting of 0, 80, 131, 160 palms ha-1, characterizing monoculture (MC), low density of palm trees (LDP), average density of palm trees (ADP) and high density of palm trees (HDP) during the rainy (RP) and dry (DP) periods. The dry matter intake, in g day-1, %BW and g kg-075 was influenced by the densities of babassu palm trees (P<0.05). In both evaluation periods, the animals kept on monoculture consumed more forage. Animals kept on HDP consumed greater amounts of CP in both periods, approximately 478.20 and 599.18 g day-1 for DP and RP, respectively. The intake of NDF was affected by periods and palm densities (P<0.05). There was a higher intake of NDF for animals kept on MC, in both periods. Of the four systems evaluated, only LDP resulted in a revenue per hectare higher than the costs, making it the only profitable system. However, in a five-year simulation, all systems resulted in an internal rate of return higher than 6,87% the rate of attractiveness, and the LDP system had the best result. All analyzed systems had a benefit/cost ratio greater than one; i.e., all are economically viable.

Resumo Este trabalho objetiva compreender como se manifesta a brincadeira de faz de conta com crianças autistas. A metodologia utilizada é o estudo de caso. Os procedimentos metodológicos envolveram intervenções educativas em situações de brincadeira, observações e registros por meio de videogravação e apoio na análise microgenética para a interpretação de episódios de brincadeira de faz de conta. Os sujeitos constam de 17 crianças, de três a seis anos, sendo seis com autismo, uma com síndrome de Down e dez sem deficiência. As crianças foram atendidas em uma brinquedoteca universitária por 13 estagiários do curso de Educação Física, uma vez por semana, durante uma hora, num período de nove meses. As análises indicam que a criança com autismo pode desenvolver o jogo imaginário de forma mais elaborada, desde que lhe sejam ofertadas condições para isso e, nesse processo, o papel mediador do professor é fundamental.

Abstract This work aims at understanding how make-believe play is expressed with autistic children. It was a case study and its methodological procedures involved educational interventions during play activities, observation and video recording, and support for micro genetic analysis to interpret make-believe play episodes. Subjects were 17 children aged 3-7, of whom six were autistic, one had Down syndrome, and ten had no disability. The children were seen at the university playroom by 13 student-teachers from the Physical Education School in their practicum, one hour a week, for nine months. The analyses indicate that autistic children are able to develop more elaborate imaginary play as long as they are provided with conditions to do so. Teachers’ mediating role is crucial in the process.

Resumen El objetivo de este trabajo es comprender cómo se manifiesta el juego imaginativo con niños autistas. La metodología utilizada es el estudio de caso. Los procedimientos metodológicos implicaron intervenciones educativas en situaciones de juegos, observaciones y registros por medio de videograbación y apoyo en el análisis microgenético para la interpretación del juego. Los participantes fueron 17 niños entre los tres y los seis años, seis de ellos tienen autismo, uno síndrome de Down y diez no tienen ninguna discapacidad. Los niños fueron atendidos en una sala de juegos universitaria por 13 pasantes de la licenciatura de Educación Física, una vez a la semana, durante una hora, en un periodo de nueve meses. Los análisis indican que los niños con autismo pueden desarrollar el juego imaginario de forma más elaborada, siempre que les sean proporcionadas condiciones para ello y, en ese proceso, el papel mediador del profesor es fundamental.

ABSTRACT Schistosomiasis is a disease of global extent reaching populations in social vulnerability. One of the control measures of this parasitosis is the use of molluscicidal substances that can fight snails of the genus Biomphalaria, intermediate hosts of Schistosoma mansoni. The aim of this work was to study the toxic activity of three mangrove species (Avicennia schaueriana Stapf. & Leech, ex Moldenke, 1939, Laguncularia racemosa (L.) CF Gaertn, 1807 and Rhizophora mangle L. 1753) on the biological activities of snails Biomphalaria glabrata. Hydroalcoholic extracts were prepared from the stem and leaves of each of the three plant species to which mollusks were exposed. The phytochemical analysis of plants showed the presence of important metabolites in the leaves and stems of L. racemosa and R. mangle, such as tannins and saponins, but the absence of these metabolites in A. schaueriana. Leaf and stem extracts of the three plant species showed low molluscicidal activity, not reaching the standards determined by the World Health Organization (WHO, 1983). L. racemosa and R. mangle has interfered with motility, feeding and oviposition of snails, unlike the extracts of A. schaueriana, which had no effect on these activities.

Abstract AIM Taurine is considered a semi-essential amino acid characterized by having various physiological functions in the body that modulate mechanisms of action involved in the muscle contraction process, increased energy expenditure, insulin signaling pathway, carbohydrate metabolism, and scavenging free radicals. These functions are crucial for aerobic exercise performance; thus, taurine supplementation may benefit athletes’ performance. The objective of this study was to evaluate the effects of taurine supplementation on the resting energy expenditure and physical performance of swimming athletes. METHODS In a double-blind study, 14 male swimmers were randomized into two groups: the taurine group (n = 7) and the placebo group (n = 7), which received 3 g per day of taurine or placebo in capsules during 8 weeks. Resting energy expenditure, plasma taurine, physical performance, anthropometry, dietary consumption were measured and an incremental test was performed to determine their maximal front crawl swimming performances before and after the 8-week period. RESULTS The levels of serum taurine (p < 0.0001) and lactate (p = 0.0130) showed a significant increase in the taurine group; however, the other variables were not different. No changes were observed in the resting energy expenditure, mean speed performed, and the anaerobic threshold of the swimmers post-supplementation period. CONCLUSION Supplementation of taurine increased plasma concentrations of this amino acid, but did not lead to significant changes in food intake, rest energy expenditure, and athletes’ performance. However, the supplemented group presented a higher lactate production, suggesting a possible positive effect of taurine on the anaerobic lactic metabolism.

Resumo O objetivo desta revisão sistemática foi analisar ensaios clínicos feitos na investigação do efeito da suplementação com vitamina D sobre o lúpus eritematoso sistêmico. A pesquisa foi feita nas bases de dados Scopus, PubMed e Biblioteca Cochrane, de agosto a setembro de 2016, sem limite de ano de publicação, restrição de gênero, idade e etnicidade. Para a questão norteadora foi empregada a estratégia Pico. Para avaliar a qualidade das publicações usaram-se o protocolo Prisma e a escala de Jadad. A análise do risco de viés dos ensaios clínicos ocorreu pela ferramenta de colaboração Cochrane. Após o processo de seleção e remoção de artigos duplicados, quatro artigos foram identificados como elegíveis. Os resultados de três estudos mostraram efeito positivo da suplementação na redução da atividade da doença e melhoria significativa nos níveis de marcadores inflamatórios, fadiga e função endotelial. Em apenas um estudo não houve melhoria na atividade da doença após a suplementação. Ademais, todos os estudos apresentaram aumento dos níveis séricos de vitamina D. Os dados desta revisão fornecem evidências dos benefícios da suplementação com vitamina D sobre o lúpus em pacientes com insuficiência/deficiência. Contudo, ainda é necessário elucidar a atuação do nutriente na proteção contra esse distúrbio metabólico, bem como a padronização do tipo, da dose e do tempo de suplementação com vitamina D.

Abstract The objective of this systematic review was to analyze clinical trials carried out for the investigation of the effect of vitamin D supplementation on systemic lupus erythematosus. The research was performed from August to September 2016, without limits regarding year of publication, restriction of gender, age, and ethnicity. For the guiding question, the PICO strategy was employed. To evaluate the quality of the publications the PRISMA protocol and Jadad scale were used. The risk of bias analysis of the clinical trials was performed using the Cochrane collaboration tool. After the process of article selection and removal of duplicates, four articles were identified as eligible. The results of three studies showed a positive effect of supplementation on disease activity reduction and significant improvement in levels of inflammatory markers, fatigue, and endothelial function. Only one study showed no improvement in disease activity after supplementation. Moreover, all studies showed an increase in serum vitamin D levels. The data from this review provide evidence on the benefits of vitamin D supplementation in patients with lupus and vitamin D insufficiency/deficiency. However, it is still necessary to elucidate whether vitamin D acts in the protection against this metabolic disorder, as well as the standardization of the type, dose and time of vitamin D supplementation.