RESUMEN El objetivo del presente estudio fue relacionar los estilos de aprendizaje, habilidades emocionales y múltiples con el rendimiento académico en estudiantes de primer año de la carrera pedagogía en educación física de una universidad de Santiago de Chile. Metodología: de tipo cuantitativa, no experimental de corte transversal. La muestra estuvo constituida por 84 estudiantes (20 mujeres y 64 hombres). Para evaluar los estilos de aprendizaje se utilizó CHAEA-36 y el Inventario Herrmann de Dominancia Cerebral, también se aplicó el Inventario de Inteligencias Múltiples (IAMI-R), el Inventario de Inteligencia Emocional y para el rendimiento académico, el acta de notas de las asignaturas cursadas en el primer semestre por el estudiantado. Resultados: se encontraron correlaciones medias bajas entre el estilo de aprendizaje activo con el rendimiento académico (r=-0,235) y la dominancia B se relaciona positivamente con las calificaciones (r=0,270). Conclusiones: son necesarios futuros estudios con un diseño longitudinal y experimental, ya que existen algunas habilidades claves para un docente integral que se debería intervenir desde los primeros años de formación.

ABSTRACT The objective of the present study was to relate learning styles, emotional and multiple skills to academic performance in first-year students of the physical education teaching career at a university in Santiago de Chile. Methodology: quantitative, non-experimental cross-sectional type. The sample consisted of 84 students (20 women and 64 men). To assess learning styles, the CHAEA-36 and the Herrmann Brain Dominance Instrument were used. The Multiple Intelligences Inventory (IAMI-R), the Emotional Intelligence Inventory were also applied, and for academic performance, the transcript of grades from the subjects taken in the first semester by the students was used. Results: low to medium correlations were found between the active learning style and academic performance (r=-0.235), and dominance B is positively related to grades (r=0.270). Conclusions: Future studies with a longitudinal and experimental design are necessary, as there are some key skills for a comprehensive teacher that should be addressed from the first years of training.

ABSTRACT Candidemia and other forms of invasive candidiasis (C/IC) are serious conditions, especially for immunosuppressed individuals with prolonged hospitalization in intensive care units (ICU). This study analyzed the incremental cost-effectiveness and budgetary impact (BI) of treatment for IC with anidulafungin compared to amphotericin B lipid complex (ABLC) and amphotericin B deoxycholate (ABD) or conventional amphotericin B (CAB), in the Brazilian Unified Health System (SUS). A decision model was conducted with a time horizon of two weeks from the perspective of SUS. The primary effectiveness endpoints were survival and treatment response rate. All patients were followed up until successful therapy or death. BI analysis was performed based on the measured demand method. A five-year time horizon was adopted based on the number of hospitalizations (per 1,000 hospitalizations). For effectiveness measured in the successful response rate (SRR), anidulafungin dominated the ABLC and ABD formulations. In the results of the analysis with the effectiveness measured according to survival, anidulafungin had a better cost-effectiveness ratio (R$988.26/survival) compared to ABD (R$16,359.50/survival). The BI estimate related to the incorporation of anidulafungin suggests savings of approximately 148 million reais in 5 years when comparing it to ABD. The economic evaluation of anidulafungin and its comparators found it to be cost-effective. The consensus of international scientific societies recommends it as a first-line drug for IC, and its incorporation by SUS would be important.

Summary Tumor lysis syndrome (TLS) is a life-threatening complication characterized by a massive lysis of tumor cells. The following is the case of a 28-year-old man diagnosed with high-grade B-cell nonHodking lymphoma. The patient presented a TLS after the administration of chemotherapy. This case is of special interest due to the pharmaco logical recommendations proposed by the Pharmacy Service regarding the rasburicasa dose and the interactions at the electrolyte level with the concomitant medication prescribed during admission.

Resumen El síndrome de lisis tumoral (SLT) es una complicación potencialmente mortal caracterizada por una lisis masiva de células tumorales. A continuación, se presenta el caso de un varón de 28 años, diagnosticado de linfoma no Hodking de células B de alto grado. Este presentó un SLT tras la administración de la quimioterapia, de especial interés debido a las recomendaciones farmacológicas propuestas desde el Servicio de Farmacia en cuanto a la dosis de rasburicasa y las interacciones a nivel electrolítico con la medicación concomitante prescrita durante el ingreso.

SUMMARY OBJECTIVE: This study aimed to translate, adapt, and analyze the reliability of the Workplace Sitting Breaks Questionnaire (SITBRQ) for use in Brazil. METHODS: This is a cross-sectional study. The translation and cross-cultural adaptation were conducted considering the following six phases: translation, synthesis of translations, back translation, analysis by a committee of experts, test of the pre-final version, and final version. We included workers aged 18 years or above, both genders, and able to understand, read, and write in Brazilian Portuguese. The final version was applied to workers in two moments (i.e., test and retest), with an interval of 7 days, for reliability calculation. RESULTS: In the translation and cross-cultural adaptation phase, the pre-final version was applied to a sample of 35 workers. For item a of the SITBRQ, there was 100% understanding by respondents, while item b was understood by 94.28%. The reliability phase was conducted with 115 workers. For both items, almost perfect was identified with kappa >0.81. CONCLUSIONS: The SITBRQ version into Brazilian Portuguese has adequate adaptation and excellent values of reliability.

OBJETIVO: Verificar a influência de diferentes sequências de exercícios no desempenho do número de repetições máximas em mulheres idosas. MÉTODOS: Doze mulheres idosas (65,7 ± 5,6 anos, 66,9 ± 9,5 kg, 1,56 ± 0,67 m; 27,4 ± 3,6 kg/m2) foram submetidas a diferentes sequências de exercícios no Treinamento Resistido. Na primeira visita, as voluntárias foram submetidas à anamnese, avaliação antropométrica e teste de 10 RM. Na segunda visita, foi feito um re-teste de 10RM. Na terceira e quarta visita, as voluntárias realizaram as duas sequências: SEQ A - supino horizontal, puxador alto fechado, rosca bíceps e rosca tríceps e, SEQ B - a ordem foi inversa. O desempenho foi medido pelo número de repetições em cada exercício. A fim de verificar as diferenças nos dados obtidos no desempenho em diferentes sequências e séries, foram realizadas medidas repetidas pela ANOVA two-way seguido do teste post-hoc de Tuckey. RESULTADOS: Os resultados demonstraram que o número de repetições de cada exercício variou significativamente entre as sequências nos exercícios de supino horizontal, rosca bíceps e rosca tríceps. CONCLUSÕES: A ordem dos exercícios realizada em uma sessão de treinamento resistido pode afetar o desempenho no número de repetições em mulheres idosas.

OBJECTIVE: Verify the influence of different exercise orders on the performance of the number of maximal repetitions in older women. METHODS: Twelve older women (65.7 ± 5.6 years, 66.9 ± 9.5 kg, 1.56 ± 0.67 m, 27.4 ± 3.6 kg/m2) underwent four nonconsecutive visits and two different orders of Resistance Training. At the first visit, the volunteers were submitted to anamnesis, anthropometric evaluation and a 10RM test. On the second visit, a re-test of 10RM was performed. On the third and fourth visits, the volunteers performed two exercise sequences: sequence A: bench press, latissimus pulldown close grip, biceps curl, triceps extension; for sequence B the order was inverted. Performance was measured by the number of repetitions in each exercise. To determine differences in performance for sequence A vs. sequence B, repeated measures were performed by two-way ANOVA followed by the Tuckey post-hoc test. RESULTS: The number of repetitions of each exercise varied significantly for the bench press, biceps curl and triceps extension between the exercise sequences. CONCLUSIONS: The order of the exercises performed in a resistance training session can affect the performance in the number of repetitions in older women.

Nós relatamos o caso de um paciente com início insidioso e lentamente progressivo de declínio cognitivo, sintomas comportamentais, crises convulsivas do lobo temporal e pensamentos delirantes típicos dos delírios monotemáticos de identificação. A apresentação clínica associada aos exames complementares levaram ao diagnóstico de encefalite límbica relacionada a linfoma difuso de grandes células B. O paciente foi submetido a imunoterapia com altas doses de corticoide sem melhora clínica. Não foi realizado tratamento específico para o linfoma em função do paciente ter evoluído para óbito por choque séptico secundário a infecção respiratória nosocomial. Os delírios monotemáticos de identificação representam uma forma única e incomum de comprometimento cognitivo nas quais o paciente consistentemente identifica de forma errônea pessoas, lugares, objetos ou eventos. A síndrome de Capgras é o subtipo mais comum dessas desordens, sendo definida como a crença recorrente e transitória que um impostor substituiu uma pessoa familiar. Essas entidades são geralmente relacionadas com doenças neurodegenerativas e distúrbios psiquiátricos. Raros relatos da associação entre os delírios monotemáticos de identificação e doenças autoimunes como esclerose múltipla foram publicados, porém não há artigos abordando a correlação com encefalite límbica ou linfoma.

We report the case of a patient with insidious onset and slowly progressive cognitive impairment, behavioral symptoms, temporal lobe seizures and delusional thoughts typical of delusional misidentification syndromes. Clinical presentation along with extensive diagnostic work-up revealed limbic encephalitis secondary to diffuse large B-cell lymphoma. The patient underwent immunotherapy with high-dose corticosteroid but no significant improvement was observed. No specific treatment for lymphoma was performed because the patient died of septic shock following a nosocomial respiratory infection. Delusional misidentification syndromes are an unusual and unique form of cognitive impairment in which a patient consistently misidentifies persons, places, objects, or events. Capgras syndrome is the most common subtype of this disorder, being defined by the recurrent and transient belief that someone close has been substituted by an imposter. These entities are generally associated with neurodegenerative diseases and psychiatric disturbances. Rare reports of associations between misidentification syndromes and autoimmune diseases such as multiple sclerosis have been published, but no papers address a correlation with limbic encephalitis or lymphoma.

Objective: To describe the results obtained with intramedullary nailing in patients with distal third tibia fracture. Methods: Patients with displaced fractures of the distal tibia treated with intramedullary nailing were included. The sample comprised 35 patients. The follow-up was 29.2 months. Time of consolidation, malunion and complications were evaluated. Functional results were described according to the AOFAS score. Results: All patients with a distal third tibia fracture (24 type A and 11 type B) presented fracture healing. The average time to union was 17.2 weeks (range 11-26). There was no difference (p = 0.201) in the time to union between fractures associated with treated or untreated fibula fractures (13 and 17 weeks, respectively). The AOFAS score was 86 points. Conclusion: Intramedullary nailing with multiple distal locks is a good alternative treatment for AO types A or B distal tibia fractures, with a low complication rate and a high rate of consolidation.

Objetivo: Describir los resultados obtenidos con el enclavado endomedular acerrojado en pacientes con fractura del tercio distal de la tibia. Materiales y Métodos: Se incluyeron pacientes con fracturas desplazadas del tercio distal de la tibia, tratadas con clavo endomedular. La muestra incluyo 35 pacientes. El tiempo de seguimiento posoperatorio fue de 29.2 meses. Se evaluaron el tiempo de consolidacion, la consolidacion viciosa y las complicaciones. Los resultados funcionales se determinaron con el puntaje de la AOFAS. Resultados: De los 35 pacientes con fractura del tercio distal de la tibia (24 de tipo A y 11 de tipo B de la clasificacion AO), en todos, se logro la consolidacion de la fractura. El tiempo promedio de consolidacion fue de 17.2 semanas (rango 11-26). No se hallo diferencia estadistica (p = 0,201) en el tiempo de consolidacion entre las fracturas asociadas con fracturas del perone tratadas (13 semanas) o no tratadas (17 semanas). El puntaje de la AOFAS fue 86. Conclusión: Se plantea el enclavado endomedular con multiples cerrojos distales como una buena alternativa de tratamiento para las fracturas de la tibia distal AO de tipo A o B, con bajo porcentaje de complicaciones y un alto indice de consolidacion.

O estudo selecionou quarenta e dois implantes que possuiam proteses totais implantosuportadas (com e sem cantilever) instaladas a pelo menos cinco anos. As radiografias foram mensuradas atraves do software Digimizer (MedCalc Software, Belgica). A mensuracao da perda ossea foi realizada na distal dos implantes, a partir da superficie da plataforma do implante ate a crista ossea marginal; e a extensao do cantilever foi mensurada a partir da superficie do implante distal ate a extremidade da estrutura da protese. Tres grupos foram formados de acordo com comprimento do cantilever: G1 = ≤ 15 mm, G2 = > 15 mm; G3 = sem cantilever. O tipo de antagonista foi agrupado em: RP = protese removivel; FP = protese fixa implanto-suportada; ND = denticao natural. A analise dos dados foi realizada de acordo com a extensao do cantilever e o tipo de arco antagonista. Utilizou-se o teste estatistico de Person's para verificacao da normalidade e Test t de Student com valor de P (P ≦ 0.05). Ao comparar G1 e G2, nao houve diferenca estatisticamente significativa, no entanto, uma perda ossea aumentada foi observada em ambos os grupos com cantilever (G1 e G2) quando comparados ao G3. Extensoes de cantilever irao causar um aumento na perda ossea marginal, porem o tipo de antagonista nao ira influenciar esta perda ossea.

This study selected forty-two implants with full arch implantsupported fixed prostheses (with and without a cantilever) with at least five years' loading. Radiographic measurements were performed using Digimizer software (MedCalc Software, Belgium). Bone loss was measured on the distal side of the implant, from the surface of the platform to the edge of the bone crest, and the extent of the cantilever was measured from the distal surface of the last abutment to the end of the metal structure. Three groups were formed according the length of the cantilever: G1: cantilever ≤ 15 mm; G2: cantilever >15 mm; G3: no cantilever. Types of antagonists were grouped as: RP = removable complete denture; FP = fixed implant-supported prosthesis; ND = natural dentition. Data were analyzed according to the length of the cantilever and type of antagonist using Person's test to analyze normality and Student's t-test with P ≦ 0.05. No statistically significant difference was found between G1 and G2; however, increased bone loss was observed in both cantilever groups (G1 and G2) compared to G3 (P> 0.05). The antagonist showed no significant difference in bone loss ( P ≦ 0.05). Cantilevers showed increases in marginal bone loss. The type of antagonist did not influence bone loss.

Foi observado na natureza o consumo da carniça de um tapiti (Sylvilagus brasiliensis) por uma fêmea reintroduzida da cutia Dasyprocta leporina. Neste estudo, além da descrição desse evento, é feita uma revisão de outras evidências de consumo de vertebrados por cutias. A maioria dos estudos que descreveram esse comportamento foi realizada em cativeiro. Os animais predados incluíram aves e pequenos roedores, que foram mortos pelas cutias em algumas ocasiões. Esse padrão sugere que esse não é um comportamento anômalo para o gênero, refletindo seus hábitos onívoros. Esse comportamento pode trazer vantagens fisiológicas para esses animais, de forma que novos estudos devem focar na variação temporal do uso desse recurso, relacionando-o com períodos de escassez e com a estação reprodutiva dos animais, onde a necessidade de alimentos de alta qualidade energética pode ser maior.

The consumption of the carrion of a tapiti by a reintroduced female Dasyprocta leporina was observed in the wild. Herein, besides describing this event, we reviewed other evidence of vertebrate consumption by agoutis. Most of the studies describing this behaviour have been carried out in captivity. The preyed animals included birds and small rodents, which were sometimes killed by agoutis. This pattern suggests that this is not an anomalous behaviour for the genus, reflecting its omnivorous habits. This behaviour can be a physiologically sound feeding strategy, so new studies should focus on the temporal variation in the consumption of this resource, possibly related to food scarcity periods or to reproductive seasons, when the need for high-quality food tends to increase.

OBJETIVO: comparar dois ângulos cervicais com as classificações oclusais em crianças de 6 a 10 anos com e sem Disfunção Temporomandibular (DTM),identificar se há prevalência de DTM quanto ao gênero, e se há influencia da oclusão sobre os ângulos estudados. MÉTODO: realizou-se um estudo observacional transversal com 91 crianças de ambos os gêneros de uma Instituição de Ensino privado, dispostas em Grupo A (sem DTM) e Grupo B (com DTM). Todas as crianças foram avaliadas seguindo uma ficha cadastral constituída de dados referentes a sexo, idade, peso, altura e exame clínico intra-oral para classificação oclusal de Angle. O diagnóstico e a severidade da DTM, foram verificados pelo questionário proposto por Fonseca. Para avaliação dos ângulos cervicais (A1 e A2) foi utilizada a fotogrametria e o Software Alcimagem®. RESULTADOS: entre as crianças avaliadas, 52 (57,14%) apresentaram maloclusão, sendo 29 com DTM e 23 sem DTM, 39 (42,85%) apresentaram normoclusão, sendo 18 sem DTM e 21 com DTM. Quando comparados os ângulos (A1 e A2) a classe oclusal, foi encontrada diferença significante entre as crianças normoclusivas e maloclusivas com o ângulo A1 (p=0,04). CONCLUSÃO: esse estudo demonstrou que o ângulo A1 (C7, ATM e Ápice do Mento) foi estatisticamente significante quando associado com a condição oclusal. Não foi encontrado associação, na população estudada, entre ângulo cervical e DTM. Além disso, também foi possível observar que, a prevalência de crianças do gênero feminino com DTM é significantemente maior que a do gênero masculino. Esse estudo demonstrou que a maloclusão pode alterar somente o ângulo A1 e que a DTM não interfere nos ângulos cervicais estudados.

PURPOSE: to compare two cervical angles with occlusal classifications in children between 6 and 10 years old with and without Temporomandibular Disorders (TMD), to identify if there is a prevalence of TMD according to gender, and if there is influence of occlusion on the studied angles. METHOD: it was conducted a cross sectional observational study with 91 children of both gender in Group A (without TMD) and Group B (TMD). All children were evaluated following a registration form consisted of sex, age, weight, height data and intra-oral clinical examination for occlusal classification of Angle. The diagnosis and severity of TMD were scanned by the questionnaire proposed by Fonseca. For the cervical angles evaluation (A1 and A2) it was used the photogrammetry and the Alcimagem® software. RESULTS: among the evaluated children, 52 (57.14%) presented malocclusion, 29 with TMD and 23 without TMD. 39 (42,85%) presented normal occlusion, 18 without TMD and 21 with TMD. When the angles were compared, it was found a difference between normal occlusion and malocclusion children with the angle A1 (p=0.04). CONCLUSION: this study demonstrated that the angle A1 (C7, TMJ and Mentum Vertex) was statistically significant when associated to the occlusal condition. No association was found in the evaluated population, between TMD and cervical angle. Besides, it was also observed that the prevalence of female children with TMD is significantly larger than the male. This study demonstrated that malocclusion can change only the angle A1 and the TMD does not interfere with the studied cervical angles.

Se ha mantenido una creciente preocupación por estudiar los factores de riesgo asociados al síndrome metabólico (SM), y diversos estudios han demostrado que el fenotipo B es altamente aterogénico debido a que estas partículas de lipoproteínas de baja densidad (LDL), consideradas pequeñas y densas, presentan una distribución espacial diferente de las LDL normales. El objetivo del estudio fue caracterizar fenotípicamente partículas de LDL en pacientes adultos con diagnóstico de SM, y asociarlo con los factores que lo definen, considerando el consenso ATP III. Se trató de un estudio descriptivo, transversal e intencional que incluyó 169 pacientes distribuidos en dos grupos, 93 pacientes con SM y 76 sin esta condición, a los cuales se les determinó glucosa, HDL, triglicéridos y electroforesis en gel de poliacrilamida para la caracterización fenotípica de la LDL. Se midió presión arterial y circunferencia abdominal. El rango de edad de la muestra estudiada estuvo entre 20 y 84 años (40,3±14,8), y de los pacientes estudiados 40,2% presentaron un fenotipo B y 59,8% un fenotipo A. Al comparar ambos grupos se evidenciaron diferencias significativas en las variables estudiadas. Se concluye que los pacientes con SM presentaron concentraciones superiores de fenotipo B en comparación con los individuos que no cumplieron con los criterios para su diagnóstico, observándose asociación significativa entre el fenotipo B y la presencia de SM. Esta asociación estuvo directamente relacionada con las concentraciones séricas de triglicéridos, obesidad abdominal y presión arterial diastólica.

Currently, there has been a steadily-growing interest on the risk factors associated with metabolic syndrome (MS), and several studies have shown that the B phenotype is highly atherogenic, since these low density lipoprotein (LDL) particles which have been considered small and dense, have a different spatial distribution from the normal LDL. The aim of this study was to characterize phenotypically LDL particles in adult patients diagnosed with SM, and to relate the latter with its defining factors, taking into account the ATP III consensus. This was a descriptive, crosssectional intentional study involving 169 patients divided into two groups, 93 patients with MS and 76 without this condition, who had glucose, HDL, triglyceride, and polyacrylamide-gel electrophoresis determinations for phenotypic characterization of LDL. Blood pressure and waist circumference were measured. The age range of the sample was between 20 and 84 years (40.3 ± 14.8); 40.2% of the studied patients were phenotype B and 59.8%, phenotype A. When comparing both groups, significant differences in the variables studied were observed. It is concluded that, compared with individuals who did not meet the criteria for diagnosis, patients with MS had higher concentrations of phenotype B. Also, there was a significant association between phenotype B and the presence of SM. This association was directly related to serum triglycerides, abdominal obesity and diastolic blood pressure.

Pathogenic strains of Escherichia coli are the most common bacteria associated with urinary tract infections in both humans and companion animals. Standard biochemical tests may be useful in demonstrating detailed phenotypical characteristics of these strains. Thirteen strains of E. coli isolated from dogs with UTIs were submitted to biochemical tests, serotyping for O and H antigens and antimicrobial resistance testing. Furthermore, the presence of papC, sfa, and afa genes was evaluated by PCR, and genetic relationships were established using enterobacterial repetitive intergenic consensus PCR (ERIC-PCR). The antimicrobial that showed the highest resistance rate among the isolates was nalidixic acid (76.9%), followed by cephalotin (69.2%), sulfamethoxazole + trimethoprim (61.5%), tetracycline (61.5%), streptomycin (53.8%), ciprofloxacin (53.8%), ampicillin (46.2%), gentamicin (30.8%) and chloramphenicol (23.1%). No isolate was resistant either to meropenem or nitrofurantoin. Among the five clusters that were identified using ERIC-PCR, one cluster (A) had only one strain, which belonged to a serotype with zoonotic potential (O6:H31) and showed the genes papC+, sfa+, afa-. Strains with the genes papC-, sfa+, afa- were found in two other clusters (C and D), whereas all strains in clusters B and E possessed papC-, sfa-, afa- genes. Sucrose and raffinose phenotypic tests showed some ability in discriminating clusters A, B and C from clusters D and E.

Introduction and objectives: this study compared the accuracy of ultrasonography in the diagnosis of gastrointestinal tumors in patients with several degrees of clinical suspicion. Material and methods: we recruited patients that were suspect for gastrointestinal neoplasia but with no evidence of localizing symptoms (group A), and patients that were suspect for colon cancer (group B) or for gastric cancer (group C). Accuracy in the diagnosis was compared for: gastric cancer in groups A and C, and for colon cancer in groups A and B. The comparison was made by using the contingency coefficient, which quantifies coincidence of endoscopic and ultrasonographic diagnoses. Results: seventy-nine patients were included in group A (48 males), wherein 12 colon and 5 gastric neoplasms were detected. Group B was comprised of 153 patients (78 males) and included 66 patients with colorectal cancer (CCR). Group C contained 58 patients (35 males), 31 of whom were diagnosed with gastric cancer. The accuracy of sonography for diagnosing colon cancer was 95.5% for group A and 87.5% for group B. The contingency coefficient for endoscopy vs. ultrasonography was greater for group A: 0.658 than for group B: 0.549. The diagnostic accuracy for gastric cancer was 97.4% for group A and 86.2% for group C. The contingency coefficient between endoscopic and ultrasonographic diagnoses was also greater in group A (0.618) than in group C (0.588). Conclusions: the accuracy of ultrasonography in diagnosing colon and gastric cancer is not lower in patients without localizing symptoms.

Introducción y objetivos: en todos los estudios publicados hasta la fecha se ha evaluado la precisión de la ecografía en el diagnóstico del cáncer de colon y del cáncer gástrico en pacientes en los que esta era la sospecha diagnóstica o ya con un diagnóstico establecido de esta patología. Nosotros, en este estudio, comparamos la sensibilidad de la ecografía en pacientes con diferentes grados de sospecha clínica. Material y método: reclutamos pacientes con sospecha de neoplasia digestiva, sin evidencia de síntomas localizadores (grupo A), pacientes con sospecha de cáncer de colon (grupo B) y pacientes con sospecha de cáncer gástrico (grupo C). Comparamos la precisión de la ecografía en el diagnóstico del cáncer gástrico en los grupos A y C, y la precisión en el diagnóstico del cáncer de colon en los grupos A y B. El parámetro usado en la comparación es el coeficiente de contigencia que cuantifica la coincidencia de diagnóstico endoscópico y ecográfico. Resultados: se han incluido 79 pacientes en el grupo A (48 varones y 31 mujeres, con una edad media de 69,3 años), en los que se han diagnosticado 12 neoplasias colónicas y 5 gástricas. El grupo B se compone de 153 pacientes (78 varones y 75 mujeres, con una edad media de 66,5 años) e incluye 66 pacientes con CCR. Finalmente, el grupo C está formado por 58 pacientes (35 varones y 23 mujeres, con una edad media de 67,4 años), siendo diagnosticados de cáncer gástrico 31 pacientes. La precisión de la ecografía en el diagnóstico del cáncer de colon fue del 95,5% en el grupo A y del 87,5% en el grupo B. El coeficiente de contingencia entre los diagnósticos endoscópico y ecográfico también fue superior en el grupo A: 0,658 frente a 0,549. La precisión de la ecografía en el diagnóstico del cáncer gástrico fue del 97,4% en el grupo A y del 86,2% en el grupo C. El coeficiente de contingencia entre los diagnósticos endoscópico y ecográfico también fue mayor en el grupo A (0,618) que en el grupo C (0,588). Conclusiones: la precisión de la ecografía digestiva en el diagnóstico del cáncer de colon y del cáncer gástrico no es inferior en los pacientes en los que no hay una sospecha específica de estas patologías.

Óleos essenciais extraídos de amostras de Chamomilla recutita (l.) Rauschert cultivadas e comercializadas na região metropolitana de Curitiba, sul do Brasil, foram analisadas por cromatografia com fase gasosa acoplada à espectrometria de massa e seus constituintes químicos comparados com uma amostra egípcia, usada como controle. A quantidade de óleo essencial obtida das amostras locais foi abaixo do padrão recomendado pela Farmacopéia Brasileira IV. Observou-se, também, diferenças na composição química desses óleos, assim como na quantidade relativa dos constituintes, como os óxidos A e B do alfa-bisabolol. De particular interesse foram os efeitos inibidores dos extratos de camomila sobre a quimiotaxia de leucócitos humanos induzida por caseína, efeito biológico descrito pela primeira vez e semelhante ao promovido pela dexametasona.

Several essential oil samples from dried flower-heads of Chamomilla recutita (L.) Rauschert, grown and commercially available around Curitiba metropolitan area, South of Brazil, were analyzed by GC-MS and the chemical constituents were compared with an Egyptian sample obtained under similar conditions and used as a control. The local grown herbs showed levels of essential oil below the standards recommended by the Brazilian Pharmacopoeia. Also, differences in their composition as well as in the quantity of several components were found such as the unexpected inversion of the relative constitution of the A and B alpha-bisabolol oxides. Of particular interest was the striking effect of the chamomile extracts upon human leukocyte chemotaxis, a biological anti-inflammatory activity not reported before, in which cell migration was in vitro inhibited at the same level as showed by dexamethasone.