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ABSTRACT Pyrrhulina brevis is an endemic fish from the Amazon basin that is valued in the ornamental fish market. In larviculture, fish are very sensitive to stressors and have a high mortality rate. Salinized water may provide more energy to overcome stress and feeding frequency is an important strategy to improve productive performance. Therefore, the aim of this study was to evaluate the best feeding frequency and the best level of water salinization for larval development of P. brevis. A total of 360 post-larvae of P. brevis (5.26 ± 1.65 mg, 5.57 ± 0.68 mm) were randomly distributed in 36 aquariums (1 L) in a 3x4 factorial scheme, to evaluate three concentrations of salt in water (0, 1 and 2 g L-1) and four feeding frequencies (once, twice, three and four times a day). We offered 150 Artemia nauplii per day and per post-larvae during 15 days. The fish kept at 1 g L-1 salinized water, and those fed 3 and 4 times a day presented significantly greater final length and weight, weight gain, and specific growth rate for length and weight. An interaction between salinized water and feeding frequency was observed for survival rate. We conclude that, during the initial rearing phase of P. brevis, feeding frequency of three times a day and salinized water at 1 g L-1 is recommended.

RESUMO Pyrrhulina brevis é um peixe endêmico da bacia amazônica que apresenta bons valores no mercado de peixes ornamentais. Na larvicultura, os peixes são muito sensíveis aos estressores e apresentam alta taxa de mortalidade. A água salinizada pode fornecer mais energia para superar o estresse e a frequência alimentar é uma estratégia importante para melhorar o desempenho produtivo. Portanto, o objetivo deste trabalho foi avaliar a melhor frequência alimentar e o melhor nível de salinização da água para o desenvolvimento larval de P. brevis. Um total de 360 pós-larvas de P. brevis (5,26 ± 1,65 mg, 5,57 ± 0,68 mm) foram distribuídos aleatoriamente em 36 aquários (1 L) em esquema fatorial 3x4, para avaliar três concentrações de sal na água (0, 1 e 2 g L-1) e quatro frequências de alimentação (uma, duas, três e quatro vezes ao dia). Foram oferecidas 150 náuplios de Artemia por dia e por pós-larva, durante 15 dias. Os peixes mantidos com 1 g L-1 de água salinizada e os alimentados 3 e 4 vezes ao dia apresentaram comprimento e peso finais, ganho de peso e taxa de crescimento específico para comprimento e peso significativamente maiores. Uma interação entre água salinizada e frequência alimentar foi observada para a taxa de sobrevivência. Concluímos que, durante a fase inicial de criação de P. brevis, recomenda-se uma frequência alimentar de três vezes ao dia e água salinizada a 1 g L-1.

https://doi.org/10.1590/1809-4392202200602

How many species of Mollusca are there in Brazil? A collective taxonomic effort to reveal this still unknown diversity
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Machado, Fabrizio M.

; Miranda, Marcel S.

; Salvador, Rodrigo B.

; Pimenta, Alexandre D.

; Côrtes, Mariana O.

; Gomes, Jaime A.J.

; Miyahira, Igor C.

; Agudo-Padrón, Ignacio

; Oliveira, Cléo D.C.

; Caetano, Carlos H.S.

; Coelho, Paulo R.S.

; D’Ávila, Sthefane

; Arruda, Eliane P. de

; Almeida, Sérgio M. de

; Gomes, Suzete R.

; Alvim, Juliana

; Galvão-Filho, Hilton

; L. Ferreira-Júnior, Augusto

; Marques, Rodrigo C.

; Martins, Inês

; Souza, Leonardo S. de

; Arruda, Janine O.

; Cavallari, Daniel C.

; Santos, Sonia B. dos

; Pedro, Natan C.

; Salles, Anna C. de A.

; Dornellas, Ana P.S.

; Lima, Tarcilla C. de

; Amaral, Vanessa S. do

; Silva, Fernanda S.

; Passos, Flávio D.

; Thiengo, Silvana S.

; Leite, Tatiana S.

; Simone, Luiz R.L.

Zoologia (Curitiba)

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2023, Volumen 40 elocation e23026

Resumen: En | Texto: En | PDF: En

ABSTRACT The expression ‘you need to know to conserve’ is a well-known cliche among biologists. Documenting the richness of a group of organisms is the first step towards understanding biodiversity and preparing efficient conservation plans. In this context, many efforts have been made to quantify the number of species on Earth and estimate the number of species still unknown to science. A few countries have complete and integrated databases estimating the approximate number of species recorded for their territory, particularly in the Global South. In Brazil, a country of continental dimensions, revealing the richness of the second most diverse clade of invertebrates (=Mollusca) has been a goal of taxonomists. Recently, in an unprecedented, collective, and integrated effort among Brazilian malacologists, it was possible to estimate how many valid species of molluscs are there in Brazil. In this effort, more than 30 mollusc experts joined together to update the Taxonomic Catalogue of the Brazilian Fauna (TCBF), a governmental website that allows a quick and real-time updating of all Metazoan. So far, more than 5,000 updates have been made in TCBF, indicating the presence of 3,552 valid species of molluscs in Brazil, distributed among the main clades as follows: Caudofoveata (10 spp.), Solenogastres (6 spp.), Polyplacophora (35 spp.), Scaphopoda (43 spp.), Cephalopoda (92 spp.), Bivalvia (629 spp.) and Gastropoda (2,737 spp.). The present study, in addition to demonstrating for the first time the richness of Brazilian molluscs, also presents the state of the art of this important phylum of invertebrates highlighting its most representative and neglected groups.

https://doi.org/10.1590/s1984-4689.v40.e23026

Oral mucositis and microbial status in acute lymphoblastic leukemia subjects undergoing high-dose chemotherapy
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Duarte, Ana Cláudia Nunes

; Barbosa, Anderson Nogueira

; Saito, Cristiane Pereira Borges

; Paula, Erich Vinicius de

; Saito, Daniel

Brazilian Journal of Oral Sciences

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2023, Volumen 22 elocation e237697

Resumen: En | Texto: En | PDF: En

Aim To assess oral microbial status in patients with acute lymphoblastic leukemia (ALL) undergoing high-dose chemotherapy and to unravel possible associations between nosocomial pathogens and the establishment of chemotherapy-induced oral mucositis (CIOM). Methods Oral mucosa, saliva, and peripheral blood samples were collected from 46 ALL subjects one day prior to chemotherapy (D0) and 2 weeks after treatment initiation (D14). Clinical intraoral inspection was performed by a single practitioner, with mucositis classification performed according to the WHO oral toxicity scale. Blood components were quantified by automatic flow cytometry, while oral Staphylococcus aureus and Pseudomonas aeruginosa were detected by Polymerase Chain Reaction with species-specific primers. Associations among bacteria and clinical findings were determined by Fisher’s Exact test, longitudinal bacterial changes by paired Macnemar, and correlations among blood parameters and mucositis status or bacteria via Mann-Whitney. Results S. aureus displayed higher detection rates at D14 (p < 0.05) and was positively associated with mucositis, adoption of a non-solid diet (all p < 0.001), nausea and fever (all p < 0.05). Conversely, P. aeruginosa did not correlate to CIOM clinical parameters. At the systemic standpoint, lower hemoglobin levels associated with CIOM and fever events (all p < 0.01). Conclusion The study evidences S. aureus as a potential pathogen in ALL-CIOM, reaffirming microbial control as an important preventive measure during high-dose immunosuppressive therapy. The weight of non-white-blood-cell parameters should be validated as novel CIOM biomarkers in prospective research.

https://doi.org/10.20396/bjos.v22i00.8667697

Síntese, caracterização de uma base de Schiff de quitosana e complexos de cobre utilizadas como eletrodo modificado
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Pontes, Ana C. F. de B.

; Pontes, Talita P. de A.

; Cavalcante, Nayara G. S.

; Sousa Júnior, Francimar Lopes de

; Silva, Francisco Ordelei N. da

; Pontes, Daniel de L.

Química Nova

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2023, Volumen 46 Nº 4 Paginas 336 - 342

Resumen: Pt | Texto: Pt | PDF: Pt

A new material formed by Shiff base (chitosan and ortho-vanillin) and copper were synthesized and characterized by UV-visible, infrared spectroscopies, thermal analysis, elemental analysis, electron microscopy, 1H NMR spectra and electrochemical techniques. In this study, it was possible to identify the formation of Schiff’s base (BS), with a degree of substitution of 42.5% by NMR. The electron microscopy study indicates an amorphous character for BS. The material was used to build an electrode, which proved to be sensitive to the addition of nitrite, making it possible to quantify it. The values obtained for detection limit and limit of quantification of the electrode formed BS-Cu were 0.062 µmol L-1 and 0.21 µmol L-1, respectively.

https://doi.org/10.21577/0100-4042.20230019

Multidisciplinary Scientific Cruises for Environmental Characterization in the Santos Basin – Methods and Sampling Design
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Moreira, Daniel L.

; Dalto, Adriana G.

; Figueiredo JR, Alberto G.

; Valerio, Aline M.

; Detoni, Amalia M. S.

; Bonecker, Ana C. T.

; Signori, Camila N.

; Namiki, Cláudia

; Sasaki, Dalton K.

; Pupo, Daniel V.

; Silva, Danilo A.

; Kutner, Deborah S.

; Duque-Castaño, Diana C.

; Marcon, Eduardo H.

; Gallotta, Fabiana D. C.

; Paula, Fabiana S.

; Gallucci, Fabiane

; Roque, Gabriela C. F.

; Campos, Giulia S.

; Fonseca, Gustavo

; Mattos, Gustavo

; Lavrado, Helena P.

; Silveira, Ilson C. A. da

; Costa, Jessica O.

; Santos Filho, João R. dos

; Carneiro, Juliane C.

; Moreira, Julio C.F.

; Rozo, Laura

; Araujo, Leandro F.M.

; Lazzari, Letícia

; Silva, Letícia O. da

; Michelazzo, Luan S.

; Fernandes, Luciano F.

; Dottori, Marcelo

; Araújo Jr., Marcus A. G. de

; Chuqui, Mateus G.

; Ceccopieri, Milena

; Borges-Silva, Milton

; Kampel, Milton

; Bergo, Natascha M.

; Silva, Paulo V. M.

; Tura, Pedro M.

; Moura, Rafael B. de

; Romano, Renato G.

; Martins, Renato P.

; Carreira, Renato S.

; Toledo, Rodrigo G.A.

; Bonecker, Sérgio L.C.

; Disaró, Sibelle T.

; Rodrigues, Silvana V.

; Corbisier, Thais N.

; Vicente, Thaisa M.

; Paiva, Vitor G. de

; Pellizari, Vivian H.

; Belo, Wellington C.

; Brandini, Frederico P.

; Sousa, Silvia H.M

Ocean and Coastal Research

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2023, Volumen 71 Supl. 3 elocation e23022

Resumen: En | Texto: En | PDF: En

Abstract The Santos Basin (SB) is the main petroliferous basin in the Brazilian continental margin and one of the most studied marine areas in Brazil. However, historical data suggest that new efforts should be carried out to acquire quantitative biological data, especially in the deep sea, to establish the baseline of essential ocean variables in different ecosystems for future monitoring programs. The Brazilian energy company Petrobras planned and executed 24 oceanographic cruises over a period of 2 years to assess the benthic (SANSED cruise) and pelagic (SANAGU cruise) systems of the SB (356 days at sea in 2019 and 2021/2022). These efforts were part of the Santos Project, which comprised a comprehensive environmental study aimed at investigating benthic and pelagic variables to characterize ecology, biogeochemistry, thermohaline properties of water masses, and ocean circulation patterns, geomorphology, and sedimentology, as well as organic and inorganic chemistry. Here we present the detailed sampling designs and the field methods employed on board, during the SB scientific cruises. All sampling protocols were based on standardized approaches. For the benthos analyses, triplicate sediment samples were performed using a GOMEX-type box corer (0.25 m²) or a large modified Van Veen grab (0.75 m²) at 100 stations ranging from 25 to 2400 m depth. At each station, 25 geochemical and physico-chemical parameters were analyzed in addition to micro-, meio-, and macrofauna and living foraminifera samples. For the pelagic system, 60 stations were selected to investigate the plankton community, ranging in size from pico- to macroplankton, through vertical, horizontal, and oblique net hauls (20, 200, and 500 μm mesh size), as well as 25 biogeochemical parameters collected with an aid of a CTD-rosette sampler. Part of this scientific information also serves the Regional Environmental Characterization Project (PCR-BS) in support of Petrobras’ Santos Basin drilling licensing process led by the Brazilian Environmental Agency – IBAMA. This project contributes to the sustainable development of the SB, in line with the guidelines of the United Nations Decade of Ocean Science for Sustainable Development.

https://doi.org/10.1590/2675-2824071.22072dlm

Different stocks of Prochilodus lineatus along the Cinzas River basin: contributions from a free-flowing tributary in the Capivara Reservoir region, Paranapanema River basin (upper Paraná River) freeflowing free flowing region upper
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Ferreira, Dhiego G.

; Galindo, Bruno A.

; Limeira, Daniel M.

; Garla, Alanna

; Marques, Ana J. C.

; Moreira, Amanda A.

; Rodrigues, Maria V. H.

; Clemente, Roberta C.

; Shimpo, Jhennifer Y.

; Martins, Gabriel A.

; Almeida, Fernanda S.

; Apolinário-Silva, Caroline

; Zanatta, Augusto S.

; Sofia, Silvia H.

; Souza-Shibatta, Lenice

Neotropical Ichthyology

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2023, Volumen 21 Nº 4 elocation e230080

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Barragens são umas das principais ameaças para peixes potamódromos Neotropicais, causando bloqueios de rotas migratórias e perdas de áreas de reprodução em um número crescente de sistemas de drenagem. Neste cenário, dados atuais defendem que a manutenção de tributários de fluxo livre em bacias hidrográficas fragmentadas seria uma importante estratégia na conservação de peixes migradores, tanto em situações de panmixia quanto em cenários com diferentes estoques coexistindo, tal como já relatado para Prochilodus lineatus. Este estudo analisou locos microssatélites e haplótipos mitocondriais em amostras de P. lineatus obtidas em diferentes anos ao longo da bacia do rio das Cinzas, no reservatório de Capivara (maior reservatório na calha principal do rio Paranapanema, alto rio Paraná) e no rio Tibagi, todos conectados por trechos livres, visando investigar as contribuições da bacia do rio das Cinzas na dinâmica populacional de peixes migradores na região do reservatório de Capivara. Ambos os marcadores detectaram altos níveis de diversidade genética e indicaram diferentes estoques de P. lineatus ao longo da bacia do rio das Cinzas, sugerindo alguma estruturação genética temporal, bem como a mistura destes estoques na amostra do reservatório de Capivara e de outros pontos, corroborando as relações de estoques neste reservatório e seus tributários. Neotropicais drenagem cenário coexistindo P maior Paranapanema Paraná Tibagi livres temporal pontos

Abstract Dams are one of the main threats to Neotropical potamodromous fish, causing blockages of migratory routes and loss of breeding areas in an increasing number of drainage systems. In this scenario, current data argue that the maintenance of free-flowing tributaries along fragmented watersheds would be an important strategy to the migratory fish conservation, both in panmixia situations and in scenarios with different coexisting stocks, as already reported for Prochilodus lineatus. This study analyzed microsatellite loci and mitochondrial haplotypes in samples of P. lineatus obtained in different years along the Cinzas River basin, as well as in the Capivara Reservoir (largest Reservoir in the Paranapanema main channel, upper Paraná River) and in the Tibagi River, all connected by free stretches, aiming to investigate the contributions of the Cinzas River basin to the population dynamics of migratory fish in the Capivara reservoir region. Both markers detected high genetic diversity levels and indicated different genetic stocks of P. lineatus along the Cinzas River basin, suggesting some temporal genetic structuring, as well as the mixture of these stocks in the sample from the Capivara reservoir and from other points, corroborating the relationships among stocks in this reservoir and its tributaries. systems scenario freeflowing flowing conservation P largest channel stretches region structuring points

https://doi.org/10.1590/1982-0224-2023-0080

Volviéndonos mejores: necesidad de acción inmediata ante el reto de la obesidad. Una postura de profesionales de la salud
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Barquera, Simón

; Véjar-Rentería, Lesly Samara

; Aguilar-Salinas, Carlos

; Garibay-Nieto, Nayely

; García-García, Eduardo

; Bonvecchio, Anabelle

; Perichart, Otilia

; Torres-Tamayo, Margarita

; Esquivias-Zavala, Héctor

; Villalpando-Carrión, Salvador

; García-Méndez, Rosalba Carolina

; Apolinar-Jiménez, Evelia

; Kaufer-Horwitz, Martha

; Martínez-Montañez, Olga Georgina

; Fajardo Niquete, Ileana

; Aguirre-Crespo, Alejandra

; Gómez-Álvarez, Enrique

; Hernández-Jiménez, Sergio C.

; Denova-Gutiérrez, Edgar

; Batis, Carolina

; Elías-López, Daniel

; Palos-Lucio, Ana Gabriela

; Vásquez-Garibay, Edgar M.

; Romero-Velarde, Enrique

; Ortiz-Rodríguez, María Araceli

; Almendra-Pegueros, Rafael

; Contreras, Alejandra

; Nieto, Claudia

; Hernández-Cordero, Sonia

; Munguía, Ana

; Rojas-Russell, Mario

; Sánchez-Escobedo, Samantha

; Delgado-Amézquita, Elvia

; Aranda-González, Irma

; Cruz-Casarrubias, Carlos

; Campos-Nonato, Ismael

; García-Espino, Fátima

; Martínez-Vázquez, Sophia

; Arellano-Gómez, Laura P.

; Caballero-Cantú, Idalia

; Hunot-Alexander, Claudia

; Valero-Morales, Isabel

; González-González, Lorena

; Ríos-Cortázar, Víctor

; Medina-García, Catalina

; Argumedo, Gabriela

; Calleja-Enríquez, Carmen Rosa

; Robles-Macías, Edna

; Nava-González, Edna J.

; Lara-Riegos, Julio

; Sánchez-Plascencia, Ana K.

; Hernández-Fernández, Mauricio

; Rodríguez-Núñez, Jose Luis

; Rangel-Quillo, Sarai

; Cancino-Marentes, Martha Edith

; Hernández-Viana, Mónica J.

; Saldivar-Frausto, Mariana

; Álvarez-Ramírez, Miriam

; Sandoval-Salazar, Cuauhtémoc

; Silva-Tinoco, Rubén Oswaldo

; Moreno-Villanueva, Mildred

; Villarreal-Arce, María Elena

; Barriguete, J. Armando

; White, Mariel

; Jauregui, Alejandra

; Tolentino-Mayo, Lizbeth

; López-Ridaura, Ruy

; Rivera-Dommarco, Juan

Salud Pública de México

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Abr 2022, Volumen 64 Nº 2 Paginas 225 - 229

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: In recent decades, the growing obesity epidemic in Mexico has become one of the most important public health challenges faced by the country. With support from the World Obesity Federation, we formed a working group in 2021 to identify and summarize priority actions that Mexico can take to face this epidemic. More than 1 000 health professionals joined the development and discussion process. Recommendations from previously published, high-level documents and guidelines were taken into account. In commemoration of World Obesity Day 2022, this statement is presented as input for health care professionals to develop actions to address obesity. The statement includes 10 recommendations that include population-level and individual-level actions. It emphasizes the importance of social participation, comprehensive interventions with a person- centered perspective, planetary sustainability, on improving education and communication campaigns, as well as fostering a built environment that promotes active living, and shielding prevention and control efforts from conflicts of interest. The statement calls for obesity to be treated seriously, based on scientific evidence, in a timely and comprehensive manner, employing a life-course and ethical approach that does not perpetuate weight stigma in society.

resumen está disponible en el texto completo

https://doi.org/10.21149/13679

Correlations between Web Searches and COVID-19 Epidemiological Indicators in Brazil
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Locatelli, Marcelo Sartori

; Cunha, Evandro L. T. P

; Guiginski, Janaína

; Franco, Ramon A. S

; Bernardes, Tereza

; Alzamora, Pedro Loures

; Silva, Daniel Victor F. da

; Ganem, Marcelo Augusto S

; Santos, Thiago H. M

; Carvalho, Anne I. R

; Souza, Leandro M. V

; Paixão, Gabriela P. F

; Chaves, Elisa França

; Santos, Guilherme Bezerra dos

; Santos, Rafael Vinícius dos

; Freitas, Amanda Cupertino de

; Flores, Matheus G

; Biezuner, Rachel F

; Cardoso, Rodolfo Lins

; Fonseca, Rodrigo Machado

; Silva, Ana Paula Couto da

; Meira Jr, Wagner

Brazilian Archives of Biology and Technology

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2022, Volumen 65 elocation e22210648

Resumen: En | Texto: En | PDF: En

Abstract: COVID-19 rapidly spread across the world in an unprecedented outbreak with a massive number of infected and fatalities. The pandemic was heavily discussed and searched on the internet, which generated big amounts of data related to it. This led to the possibility of attempting to forecast coronavirus indicators using the internet data. For this study, Google Trends statistics for 124 selected search terms related to pandemic were used in an attempt to find which keywords had the best Spearman correlations with a lag, as well as a forecasting model. It was found that keywords related to coronavirus testing among some others, such as “I have contracted covid”, had high correlations (≥0.7) with few weeks of lag (≤4 weeks). Besides that, the ARIMAX model using those keywords had promising results in predicting the increase or decrease of epidemiological indicators, although it was not able to predict their exact values. Thus, we found that Google Trends data may be useful for predicting outbreaks of coronavirus a few weeks before they happen, and may be used as an auxiliary tool in monitoring and forecasting the disease in Brazil.

https://doi.org/10.1590/1678-4324-2022210648

In vitro and ex vivo antiplasmodial activity of 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) against circulating strains of Plasmodium spp. in the state of Rondônia, Brazil
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Vicentini, Vanessa Margarida

; Nascimento, Welington da Silva Paula do

; Almeida, Marcinete Latorre

; Medeiros, Daniel Sol Sol de

; Santos, Ana Paula de Azevedo dos

; Costa, Joana D ‘Arc Neves

; Pereira, Dhélio Batista

; Tada, Mauro Shugiro

; Calderon, Leonardo de Azevedo

; Teles, Carolina Bioni Garcia

Brazilian Journal of Pharmaceutical Sciences

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2022, Volumen 58 elocation e20453

Resumen: En | Texto: En | PDF: En

Abstract Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study of chemotherapeutic alternatives extremely important. This study aimed to evaluate the antimalarial activity of compound 3286938 (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one), which presents in its structure a 3,4,5-trimethoxyphenyl group, in vitro, using the W2 strain of P. falciparum and against circulating strains of P. vivax and P. falciparum from the state of Rondônia. The compound 3286938 obtained an IC50 of 24.4 µM against the W2 strain of P. falciparum, and against the circulating strains, it presented a median (MD)=38.7 µM for P. vivax and MD=6.7 µM for P. falciparum. As for toxicity, 3286938 showed CC50 > 500 µM for VERO and HepG2 strains with a selectivity index greater than 12.9, a ratio calculated for P. falciparum and P. vivax regarding Vero and HepG2 cells. The compound was not considered hemolytic in in vitro assays, thus indicating the specificity of its antiplasmodial action. Based on the results presented, and considering the unprecedented character of the compound, it can be concluded that 3286938 was shown to be promising for complementary in vitro and in vivo studies aiming to produce effective antiplasmodial action.

https://doi.org/10.1590/s2175-97902022e20453

10.

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
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Basquiera, Ana L.

; García, Mercedes J

; Martinez Rolón, Juliana

; Olmedo, Julieta

; Laviano, Julia

; Burgos, Rubén

; Caeiro, Gastón

; Remaggi, Guillermina

; Raña, Pablo

; Paoletti, Mariano

; González, Carlos M.

; Fernández, Isolda

; Pavlovsky, Astrid

; Perusini, Maria A.

; Rodriguez, Andrea

; Guanchiale, Luciana

; Carvani, Analia

; Mandrile, Laura

; Figueroa, Flavia

; Vicente Reparaz, Ángeles

; Fragapane Mathus, Patricia N.

; Garate, Gonzalo

; Fauque, María E.

; Kantor, Gustavo

; Cruset, Soledad

; Gonzalez Lorch, Jacqueline S.

; Szelagowski, Milagros

; Giarini, María P.

; Oliveira, Natalia

; García, María C.

; Ventriglia, María V.

; Pereyra, Patricio H.

; Gutierrez, Daniel R.

; Kusminsky, Gustavo

; Troccoli, Josefina

; Freitas, María J.

; Cranco, Santiago

; Del V.Sanchez, Natalia

; Rey, Irene

; Funes, María E.

; Jarchum, Sol

; Freue, Julian

; Miroli, Augusto

; Guerrero, Osvaldo

; López Ares, Lisa

; Campestri, Reinaldo

; Bove, Victor

; Salinas, Graciela N.

; Cabrejo, María

; Milone, Jorge H.

; Zabaljauregui, Soledad

; Gotta, Daniel

; Dupont, Juan Carlos

; Stemmelin, German

Medicina (Buenos Aires)

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Ago 2021, Volumen 81 Nº 4 Paginas 536 - 545

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in pa tients with a hematological disease in Argentina. A completely anonymous survey from the Argentine Society of Hematology was delivered to all the hematologists in Argentina; it started in April 2020. A cut-off to analyze the data was performed in December 2020 and, finally, 419 patients were reported and suitable for the analysis (average age: 58 years, 90% with malignant diseases). After the COVID-19 diagnosis, the 30-day OS for the whole population was 80.2%. From the entire group (419), 101 (24.1%) individuals required intensive care unit admission, where the 30-day OS was 46.6%. Among allogeneic stem cell transplant recipients, the 30-day OS was 70.3%. Factors associated with a low OS were two or more comorbidities, an active hematological disease and history of chemotherapy. In individuals with the three factors, the 30-day OS was 49.6% while the 30-day OS in those without those factors was 100%. Patients with hematological diseases have a higher mortality than the general population. This group represents a challenge and requires careful decision-making of the treatment in order not to compromise the chances of cure.

Resumen El presente estudio tuvo por objetivo primario conocer la mortalidad de pacientes con enfermedad hematológica que presentaron infección por COVID-19 en Argentina. Para ello se difundió una encuesta desde la Sociedad Argentina de Hematología (SAH) entre los hematológos para informar sobre los pacientes con enfermedades hematológicas y diagnóstico de infección por SARS- CoV-2, entre el 19/4/2020, y el 7/12/2020. Se incluyeron individuos de todas las edades con diagnóstico de enfermedad hematológica benigna o maligna e infección por SARS-CoV-2 confirmada por técnica de RT-PCR. Se analizaron 419 pacientes (mediana 58 años; 90% enfermedades malignas). La supervivencia al día 30 fue de 80.2%. La supervivencia fue menor en aquellos que requirieron internación (74.2%), cuidados intensivos (46.6%) y asistencia respiratoria mecánica (36.8%). Entre los trasplantados alogénicos la supervivencia fue 70.3%. Los factores vinculados a la supervivencia global fueron las comorbilidades, el estado de la enfermedad al momento de la infección y el antecedente de quimioterapia. Se pudo establecer un score en el que aquellos que tuvieron un puntaje de 4 alcanzaron una supervivencia del 49.6% al día 30, mientras que la de los pacientes con score 0 fue del 100% a 30 días. En comparación con la población general, los pacientes con enfermedades hematológicas presentan una mayor mortalidad vinculada al COVID-19, motivo por el cual es primordial definir pautas destinadas a disminuir la exposición de los mismos sin comprometer las posibilidades de beneficiarse del tratamiento de la enfermedad de base.

121 descargas

11.

Modificación de la composición corporal con la terapia hormonal parenteral y oral en la menopausia
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Hernández-Hernández, Daniel I.

; Hernández-Saldivar, María Guadalupe

; Hernández-Valencia, Marcelino

; Taracena-Priego, Christopher

; Arrañaga-Macías, Antonella

; Camacho-Méndez, Karina

; Rosas-Luna, Miriam

; Ruíz-Albarrán, Miriam

; Vázquez-Martínez, Ana L.

; Vega-García, Sara

; Álvarez-Zúñiga, Irma

; Saucedo-García, Renata P.

Perinatología y reproducción humana

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Ago 2021, Volumen 35 Nº 2 Paginas 45 - 50

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Antecedentes: La menopausia se relaciona con cambios en la composición corporal que el uso de terapia hormonal (TH) puede revertir. Objetivo: Determinar el efecto de la TH parenteral y oral sobre la composición corporal en la menopausia. Material y métodos: Se realizó un estudio retrolectivo que incluyó a 86 mujeres de 45 a 55 años, con FSH > 20 Ul/ml, antecedente de histerectomía y sintomatología vasomotora, a las cuales se les administró TH por vía oral (44 pacientes) o parenteral (42 pacientes) durante seis meses. Se les realizó impedancia bioeléctrica antes y después del tratamiento. Resultados: La TH por vía oral se asoció con una disminución de diferentes parámetros de la composición corporal entre los que destaca la disminución de la grasa visceral (p < 0.05). La TH parenteral no mostró modificación en la composición corporal. Conclusión: La TH por vía oral modifica de manera positiva la composición corporal, lo cual puede contribuir a regular el estado metabólico.

Abstract Background: Menopause is associated with changes in body composition that the use of hormone therapy (HT) can reverse. Objective: To determine the effect of parenteral and oral HT on body composition in menopause. Material and methods: A retrolective study was carried out in 86 women aged 45 to 55 years old, with FSH > 20 Ul/ml, a history of hysterectomy and vasomotor symptoms. The participants received oral HT (44 patients) or parenteral (42 patients) for six months. Bioelectrical impedance was performed before and after treatment. Results: Oral HT was associated with a decrease in different parameters of body composition, among which the decrease in visceral fat stands out (p < 0.05). Parenteral HT did not show changes in body composition. Conclusion: Oral HT positively modifies body composition, which can help regulate the metabolic state.

https://doi.org/10.24875/per.19000078 43 descargas

12.

Solventes eutéticos naturais profundos (NADES) no preparo de amostras de rocha fosfática e suplemento mineral para determinação elementar por técnicas de plasma
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Santana, Ana P. R.

; Andrade, Daniel F.

; Guimarães, Taciana G. S.

; Amaral, Clarice D. B.

; Oliveira, Andrea

; Nogueira, Ana R. A.

; Gonzalez, Mario H.

Química Nova

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Jun 2021, Volumen 44 Nº 6 Paginas 689 - 695

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Natural deep eutectic solvents (NADES) based on xylitol, citric acid, and malic acid were synthesized and used in ultrasound-assisted extraction (UAE) and heating-bath extraction of phosphate rock and mineral supplement samples. Arsenic, Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, P and Zn were determined by inductively coupled plasma mass spectrometry (ICP-MS) and inductively coupled plasma optical emission spectrometry (ICP OES). The results showed the NADES as promising solvents for extraction of inorganic matrices compared to reference values and concentrations obtained using microwave-assisted acid digestion (MW-AD). Significant differences were observed for some elements, suggesting different chemical interactions between the synthesized NADES and each monitored element. For analytes extraction of phosphate rock, UAE presented the best results for As, Cr and P. Zinc was extracted with UAE and heating bath. Concerning mineral supplement, no significant differences were observed for Ca (UAE), Cd (UAE and heating bath), K (UAE and heating bath), Mn (UAE and heating bath), Na (UAE and heating bath), and P (UAE and heating bath). The NADES is a greener and a potentially alternative for the sample preparation compared to the official methods of analysis, can being used as selective extractor solvent in conventional sample preparation methods.

https://doi.org/10.21577/0100-4042.20170723 130 descargas

13.

Drying kinetics of ‘gueroba’ (Syagrus oleracea) fruit pulp
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Jorge, Ana P. P.

; Ferreira Junior, Weder N.

; Silva, Lígia C. de M.

; Oliveira, Daniel E. C. de

; Resende, Osvaldo

Revista Brasileira de Engenharia Agrícola e Ambiental

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Ene 2021, Volumen 25 Nº 1 Paginas 23 - 29

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O fruto de gueroba pode ser utilizado na produção de farinhas com potencial para o desenvolvimento de novos produtos oriundos da sociobiodiversidade do Cerrado. Objetivou-se estimar a cinética de secagem, bem como determinar o coeficiente de difusão efetivo e a energia de ativação para a polpa dos frutos de gueroba submetida a diferentes temperaturas de secagem. Os frutos de gueroba foram despolpados manualmente, retirando o mesocarpo com o epicarpo, sendo esse material identificado como a polpa. O material foi submetido à secagem em estufa nas temperaturas de 40, 50, 60 e 70 °C. Aos dados experimentais foram ajustados modelos de regressão não linear. O modelo mais adequado foi selecionado com base no coeficiente de determinação, erro médio relativo e estimado, teste de Qui-quadrado, AIC e BIC. Com o aumento da temperatura de secagem, menor é o tempo do processamento para se atingir o mesmo teor de água, devido ao aumento da difusividade da água no interior do produto. O modelo de Midilli apresentou o melhor ajuste aos dados experimentais obtidos. Os coeficientes de difusão efetivos da polpa dos frutos de gueroba apresentaram magnitudes entre 3,11 x 10-9 a 5,84 x 10-9 m2 s-1 para as temperaturas de 40 a 70 °C. A energia de ativação do processo foi de 18,34 kJ mol-1.

ABSTRACT The ‘Gueroba’ fruit can be used to produce flours with potential for the development of new products from the ‘Cerrado’ socio-biodiversity. The objective was to estimate the drying kinetics and determine the effective diffusion coefficient and activation energy for the pulp of ‘gueroba’ fruits subjected to different drying temperatures. ‘Gueroba’ fruits were manually pulped, removing the mesocarp with the epicarp, and this material was identified as the pulp. The material was subjected to oven drying at temperatures of 40, 50, 60 and 70 °C. Nonlinear regression models were fitted to the experimental data. The most adequate model was selected through the coefficient of determination, mean relative and estimated errors, Chi-square test, AIC and BIC. As the drying temperature increases, the processing time to achieve the same moisture content decreases, due to the increase in water diffusivity inside the product. The Midilli model showed the best fit to the experimental data obtained. The effective diffusion coefficients of the pulp of ‘gueroba’ fruits showed magnitudes between 3.11 x 10-9 to 5.84 x 10-9 m2 s-1 for temperatures from 40 to 70 °C. The activation energy of the process was 18.34 kJ mol-1.

https://doi.org/10.1590/1807-1929/agriambi.v25n1p23-29 626 descargas

14.

Ectoparasitic flies (Diptera: Streblidae) on bats (Mammalia: Chiroptera) from a Private Natural Heritage Reserve in southeastern Brazil
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Menezes Júnior, Luis Fernando

; Menezes, Ana Carolina Duarte Pinto

; Santos, Daniel Medina Corrêa

; Peracchi, Adriano Lúcio

Papéis Avulsos de Zoologia

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2021, Volumen 61 elocation e20216102

Resumen: En | Texto: En | PDF: En

Abstract Due to the small number of records of Streblidae on bats, despite extensive study on these mammals in the state of Rio de Janeiro, a survey was carried out in an area of the Atlantic Forest. The present study was carried out at Bom Retiro Farm Natural Heritage Private Reserve. We captured 401 bats of 17 species, 13 genera, and four families; bat flies infested 221 bats of only four species. Carollia perspicillata (Linnaeus, 1758) has the highest fly diversity, with seven fly species: Trichobius joblingi (Wenzel, 1966) (n = 23), Megistopoda proxima (Séguy, 1926) (n = 15), Strebla guajiro (García & Casal, 1965) (n = 15), Aspidoptera falcata (Wenzel, 1976) (n = 6) Paratrichobius longicrus (Miranda Ribeiro, 1907) (n = 8), Paraeuctenodes similis (Wenzel 1976) (n = 3), and Trichobius anducei (Guerrero, 1998) (n = 1). Two species infested Platyrrhinus lineatus (É. Geoffroy, 1810): Aspidoptera falcata (n = 1) and Anastrebla caudiferae (Wenzel, 1996) (n = 1). Paradyschiria parvula (Falcoz, 1931) (n = 11) infested Noctilio leporinus (Linnaeus, 1758) and M. proxima (n = 12) and Trichobius uniformis (Curran, 1935) (n = 1) infested Sturnira lilium (É. Geoffroy, 1842). Sturnira lilium has the highest infestation rate, with ten out of 46 captured individuals parasitized, followed by Carollia perspicillata, with 33 out of 164 captured parasitized, and by P. lineatus with only two parasitized individuals out of ten. Among 97 streblid flies captured, M. proxima was the most abundant (27.83%), followed by T. joblingi (23.71%), and S. guajiro (15.46%). All remaining bat fly species represented 33%. Paradichyria parvula has the first record for Rio de Janeiro State.

https://doi.org/10.11606/1807-0205/2021.61.02 502 descargas

15.

Biomass Sorghum: Effect of Acid, Basic and Alkaline Peroxide Pretreatments on the Enzymatic Hydrolysis and Ethanol Production
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Santos, Beatriz Vieira dos

; Travaini, Rodolfo

; Lorenzo-Hernando, Ana

; Pasquini, Daniel

; Baffi, Milla Alves

Brazilian Archives of Biology and Technology

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2021, Volumen 64 elocation e21200117

Resumen: En | Texto: En | PDF: En

Abstract This study evaluated the effects of three chemical pretreatments of biomass sorghum (BS): dilute alkaline (PTA1 and PTA2), dilute acid (PTB1 and PTB2) and alkaline hydrogen peroxide (PTC1 and PTC2) in the enzymatic hydrolysis and ethanol production. Among the six investigated conditions, the pretreatment with 7.36% H2O2 (PTC2) was the most efficient in the lignin removal and preservation of the polysaccharide fraction. After the enzymatic hydrolysis, increases in the glucose and xylose concentrations were observed in the pretreated BS hydrolysates, mainly in PTB1 and PTC1. All the hydrolysates obtained low concentrations of inhibitors. In the alcoholic fermentations with Pichia stiptis, the greatest ethanol yield was obtained in PTB1 hydrolysate (3.84 g L-1), corresponding to 16.15% of yield. The highest ethanol yield in PTB1 hydrolysate can be justified by the maximum concentration of xylose obtained in this hydrolysate, demonstrating the potential of P. stiptis in the fermentation of pentose to ethanol. The results indicated that biomass sorghum is an alternative lignocellulose source with potential for the production of second generation ethanol, opening up prospects for additional studies.

https://doi.org/10.1590/1678-4324-2021200117 241 descargas

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