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Abstract Background: One of the main adverse reactions of adjuvant radiotherapy for breast cancer is radiodermatitis. Objective: To assess the incidence of radiodermatitis in women with breast cancer, identify factors associated with its severity and determine the time at which this event occurs. Methods: Prospective cohort study in 113 women with breast cancer who were evaluated before radiotherapy and at every fifth session until the end of treatment. Logistic regression and Cox proportional regression model were used for the assessment of risk factors; P values < 0.05 were considered significant. Results: The incidence rate of radiodermatitis was 98.2% and it was demonstrated that for each additional point of the Body Mass Index (BMI), the chance of occurrence of grades II to IV radiodermatitis increases by 14% (OR = 1.14 [95% CI 1.04–1.26]; p = 0.004) and statin use increases the risk of more severe skin lesions by four-fold (OR = 4.27 [95% CI 1.11–16.42]; p = 0.035). The exclusive use of hydrogel for skin hydration was an independent factor in delaying the onset of radiodermatitis (HR = 0.55 [95% CI 0.36–0.82]; p = 0.004). Study limitations: The main limitation of this study was its external validity. The identified factors should be considered for services and populations similar to those in this study. Conclusions: There was a high incidence of radiodermatitis and its severity was related to higher BMI, statin use; there was a protective effect of hydrogel use.

https://doi.org/10.1016/j.abd.2023.01.004

Molecular characterization of Astyanax species (Characiformes: Characidae) from the upper Paraguaçu River basin, a hydrographic system with high endemism
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Silva-Santos, Rosane

; Machado, Carolina de Barros

; Zanata, Angela Maria

; Camelier, Priscila

; Galetti Jr, Pedro Manoel

; Freitas, Patrícia Domingues de

Neotropical Ichthyology

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2023, Volumen 21 Nº 2 elocation e230032

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Molecular tools have been employed to improve the knowledge about freshwater Neotropical fishes. Such approaches supporting studies of groups including species complexes such as Astyanax, one of the most diversified and taxonomically complex genus of the family Characidae. Here, we employed species delimitation analyses in four Astyanax species described for the upper Paraguaçu River basin, a drainage within Northeastern Mata Atlântica freshwater ecoregion with high endemism. We implemented single and multilocus approaches based on two mitochondrial and one nuclear markers. Cytochrome c Oxidase I sequences previously available for Astyanax species were also added to our dataset. The single locus analyses showed A. epiagos, A. rupestris, and A. aff. rupestris as different Molecular Operational Taxonomic Units (MOTUs), while A. brucutu and A. lorien were grouped. However, the multilocus approach distinguished these two species and showed congruence for the remaining single locus results. Astyanax aff. rupestris was separated into two MOTUs using both approaches, highlighting the need for an integrative taxonomic revision including A. aff. rupestris. These findings contribute to a better understanding of the diversity of this fish group in the upper Paraguaçu, identifying hidden diversity and reinforcing the relevance of this hydrographic system as a notable hotspot for ichthyofauna biodiversity endemism.

Resumo Ferramentas moleculares têm sido empregadas para melhorar o conhecimento sobre os peixes Neotropicais. Tais abordagens apoiam estudos de grupos que incluem complexos de espécies, como Astyanax, um dos gêneros mais diversificados e taxonomicamente complexos dentro da família Characidae. Neste estudo, nós empregamos análises de delimitação de espécies em quatro espécies de Astyanax recentemente descritas da bacia do alto rio Paraguaçu, uma drenagem dentro da ecorregião Mata Atlântica Nordeste que apresenta alto endemismo. Nós realizamos abordagens de loco único e multilocos baseadas em dois marcadores mitocondriais e um nuclear. Sequências de Citocromo c Oxidase I anteriormente disponíveis para espécies de Astyanax foram adicionadas ao nosso conjunto de dados. As análises de loco único mostraram A. epiagos, A. rupestris e A. aff. rupestris como diferentes Unidades Taxonômicas Operacionais Moleculares (MOTUs), enquanto A. brucutu e A. lorien foram agrupadas. Entretanto, a abordagem multilocos distinguiu estas duas espécies e mostrou congruência com os demais resultados das análises de loco único. Astyanax aff. rupestris foi separada em duas MOTUs usando ambas as abordagens, sugerindo a necessidade de uma revisão taxonômica integrativa incluindo A. rupestris e ambas A. aff. rupestris. Esses achados contribuem para uma melhor compreensão da diversidade desse grupo de peixes na bacia do rio Paraguaçu, identificando diversidade oculta e reforçando a relevância desse sistema hidrográfico como um notável hotspot de endemismo da biodiversidade da ictiofauna.

https://doi.org/10.1590/1982-0224-2023-0032

Oral and oropharyngeal cancer: time from first symptoms to treatment initiation and associated factors
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COSTA, Adriana Aparecida Silva da

; CALDEIRA, Patrícia Carlos

; SOUSA, Alexandre Andrade

; TIBÚRCIO, Jacqueline Domingues

; BELLIGOLI, Leonardo de Queiroz Gomes

; SANTOS, Viviane Bigodeiro dos

; BRETAS, Pedro Messeder Caldeira

; NUNES, Louise Lanna

; PRADO NETO, Severino Correia do

; SILVA, Gustavo Waldolato

; SOARES, João Marcos Arantes

Brazilian Oral Research

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2023, Volumen 37 elocation e054

Resumen: En | Texto: En | PDF: En

Abstract The aim of this study was to evaluate the time elapsed from first symptoms to the treatment of oral and oropharyngeal cancer (OOC) and to identify variables associated with treatment delay. This is an observational study with retrospective and prospective data collection. Patients with a diagnosis of OOC seen at the Head and Neck Surgery outpatient clinic of a Brazilian public hospital were included and followed up to treatment initiation. Participants answered a questionnaire for the collection of socioeconomic, demographic, cultural, and clinical information, as well as information about the time elapsed from first symptoms to the first appointment with a head and neck surgeon. Time to treatment was classified into four intervals: 1- first symptoms to first medical appointment; 2- first medical appointment to specialized medical care; 3- specialized medical care to preparation for treatment; and 4- preparation for treatment to treatment initiation. Bivariate statistics were computed. Out of 100 participants, nine died before treatment. Mean time to treatment was 217 days. Highest mean time was observed for interval 2 (94 days), followed by interval 1 (63 days), interval 4 (39 days), and interval 3 (21 days). At interval 1, a longer time was associated with severe alcohol consumption, severe smoking, and family history of cancer. At interval 2, the delay was associated with appointment with a general practitioner, clinical diagnosis of disease other than cancer, and antibiotic prescription. At interval 4, delay in treatment was associated with surgical treatment. Patients with OOC experience delays from symptom onset to treatment initiation. The longest interval was associated with professional delay, followed by patient delay in help-seeking.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0054

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volumen 37 elocation e126

Resumen: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

Supportive Care in Chronic Kidney Disease: Is it an Option?
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Domingues, Patrícia

; Piedade, Ana

; Furtado, Teresa

; Inácio, António

; Mendes, Beatriz

; Valério, Patrícia

; Farinha, Ana

Portuguese Journal of Nephrology & Hypertension

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Dic 2022, Volumen 36 Nº 4 Paginas 241 - 245

Resumen: En | Texto: En | PDF: En

ABSTRACT Supportive care in patients with chronic kidney disease refers to the application of palliative medicine principles and practices in nephrology. The main purpose is to reduce suffering by managing symptoms, helping with decision making and providing holistic support to the patient and family/caregiver in clinical, social, spiritual or nutritional distress, with a multidisciplinary team. We present the case of a 92-year-old male patient with chronic kidney disease of unknown etiology since 2004. In 2019, he was referred to our kidney disease supportive care program, presenting a serum creatinine of 5.44 mg/dL (estimated glomerular filtration rate of 9 mL/min/1.73 m2). During the following three years, the patient lived at home independently, maintained good control of his chronic kidney diseaseassociated symptoms and preserved his functional status. We present this case as a practical example of how to approach an autonomous elderly, chronic kidney disease patient, with few comorbidities, who opted for supportive care.

https://doi.org/10.32932/pjnh.2022.10.205

Behind a Paralyzing Pandemic: Renal Cortical Necrosis
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Furtado, Teresa

; Abrantes, Catarina

; Domingues, Patrícia

; Natário, Ana

; Góis, Mário

; Sousa, Helena

Portuguese Journal of Nephrology & Hypertension

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Jun 2022, Volumen 36 Nº 2 Paginas 77 - 79

Resumen: En | Texto: En | PDF: En

ABSTRACT Renal cortical necrosis (RCN) is a rare cause of acute kidney injury (AKI) in developed countries. Drugs, especially non-steroidal antiinflammatory drugs, (NSAIDs) are very rarely described in the literature to cause cortical necrosis. It is characterized by confluent necrosis of the entire cortex apart from a thin rim of viable tissue in the subcapsular, juxtaglomerular areas, and medulla. Although the pathogenesis of the disease remains unclear, the final common pathway is permanent occlusion of afferent arterioles and interlobular arteries in the cortical vasculature. NSAIDs are widely prescribed in general clinical practice. Despite being readily available, a subset of individuals is susceptible to serious renal toxicity and caution should be exercised when these drugs are used. We present the case of a young adult who presented with renal cortical necrosis with irreversible renal failure. Unfortunately, it occurred as a result of inappropriate use of over-the-counter NSAIDs in the setting of the pandemic outbreak of COVID-19.

https://doi.org/10.32932/pjnh.2022.06.179 17 descargas

Prevenção do Tromboembolismo Venoso na Gravidez, Parto e Pós-Parto: Norma de Orientação Clínica
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Lima, Jorge

; Domingues, Ana Patrícia

; Amaral, Ana Cristina

; Borges, Augusta

; Nogueira-Silva, Cristina

; Serrano, Fátima

; Marques, Inês

; Pinto, Luísa

; Guimarães, Mariana

Acta Obstétrica e Ginecológica Portuguesa

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Mar 2022, Volumen 16 Nº 1 Paginas 75 - 81

Resumen: Pt | Texto: Pt | PDF: Pt

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Audiologists’ knowledge of and adherence to biosafety measures
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Duarte, Patrícia Brollo

; Aita, Aline Domingues Chaves

Revista CEFAC

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2022, Volumen 24 Nº 4 elocation e4722

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: identificar as práticas de biossegurança adotadas por audiologistas, bem como sua percepção a respeito dos riscos aos quais estão expostos. Métodos: participaram deste estudo 63 fonoaudiólogos audiologistas clínicos e ocupacionais atuantes no Estado do Rio Grande do Sul - RS. A pesquisa foi realizada de forma on-line, no período de abril a maio de 2022, por meio de um questionário eletrônico do Google Forms® e utilizou-se para a coleta de dados o Questionário de Biossegurança em Audiologia proposto por Rocha et al. (2015). Resultados: a maioria dos profissionais relatou adotar as seguintes práticas: higienização das mãos antes dos atendimentos (86%), higienização das mãos entre os atendimentos (81%), realização de antissepsia com álcool (87,5%), jaleco com barreira de proteção (87%) e abotoado (79%), unhas limpas e cortadas (97%), desinfecção e separação dos artigos utilizados (94%) e organização do ambiente (97%). Entretanto 41% dos entrevistados referiram deixar o local de trabalho com equipamentos de proteção individual (EPI), apenas 22% e 14%, respectivamente, relataram utilizar luvas na realização de meatoscopia e nos exames auditivos. Conclusão: os resultados desta pesquisa indicaram que a maioria dos fonoaudiólogos entrevistados, atuantes na área de audiologia, conhecem e praticam as medidas de biossegurança indicadas nas normativas vigentes.

ABSTRACT Purpose: to identify biosafety measures taken by audiologists and their perception of the risks to which they are exposed. Methods: the sample comprised 63 speech-language-hearing therapists who work with clinical and occupational audiology in the state of Rio Grande do Sul, Brazil. The research was conducted online between April and May 2022 via Google Forms®, collecting data with the Audiology Biosafety Questionnaire proposed by Rocha et al. (2015). Results: most professionals reported taking the following measures: washing hands before patient visits (86%), washing hands in-between patient visits (81%), using hand sanitizers (87.5%), wearing white coats that covered their clothes (87%) and keeping them buttoned up (79%), keeping nails clean and trimmed (97%), disinfecting and separating used equipment (94%), and organizing the environment (97%). However, 41% of interviewees left the workplace wearing personal protective equipment, and only 22% and 14%, respectively, wore gloves when performing otoscopy and auditory examinations. Conclusion: research results show that most of the interviewed speech-language-hearing therapists who work in audiology know and practice the biosafety measures indicated in the existing norms.

https://doi.org/10.1590/1982-0216/20222444722

Valor Prognóstico de Níveis Elevados de Troponina I Isolados em Pacientes sem Síndrome Coronariana Aguda Admitidos no Serviço de Emergência
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Domingues, Célia

; Ferreira, Maria João Vidigal

; Ferreira, Joana Moura

; Marinho, Ana Vera

; Alves, Patrícia Marques

; Ferreira, Cátia

; Fonseca, Isabel

; Gonçalves, Lino

Arquivos Brasileiros de Cardiologia

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Nov 2021, Volumen 116 Nº 5 Paginas 928 - 937

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: Embora a elevação não isquêmica da troponina seja frequentemente observada em pacientes admitidos no pronto-socorro (PS), não há consenso quanto ao seu manejo. Objetivos: Este estudo teve como objetivo caracterizar os pacientes admitidos no PS com elevação da troponina não-isquêmica e identificar potenciais preditores de mortalidade nessa população. Métodos: Este estudo observacional retrospectivo incluiu pacientes do PS com resultado positivo no teste da troponina entre junho e julho de 2015. Pacientes com diagnóstico clínico de síndrome coronariana aguda (SCA) foram excluídos. Os dados demográficos dos pacientes e as variáveis clínicas e laboratoriais foram extraídos dos prontuários médicos. Os dados do seguimento foram obtidos por 16 meses ou até a ocorrência de morte. O nível de significância estatística foi de 5%. Resultados: A elevação da troponina sem SCA foi encontrada em 153 pacientes no PS. A mediana (IIQ) de idade dos pacientes foi de 78 (19) anos, 80 (52,3%) eram do sexo feminino e 59 (38,6%) morreram durante o seguimento. A mediana do período de seguimento (IIQ) foi de 477 (316) dias. Os sobreviventes eram significativamente mais jovens 76 (24) vs. 84 (13) anos; p=0,004) e apresentaram uma maior proporção de elevação da troponina isolada (sem elevação da creatina quinase ou mioglobina) em duas avaliações consecutivas: 48 (53,9%) vs. 8 (17,4%), p<0,001. Os sobreviventes também apresentaram menor taxa de tratamento antiplaquetário e internação no mesmo dia. Na regressão logística multivariada com ajuste para variáveis significativas na análise univariada, a elevação isolada da troponina em duas avaliações consecutivas mostrou hazard ratio = 0,43 (IC95% 0,17–0,96, p=0,039); hospitalização, tratamento antiplaquetário anterior e idade permaneceram independentemente associados à mortalidade. Conclusões: A elevação isolada da troponina em duas medidas consecutivas foi um forte preditor de sobrevida em pacientes no PS com elevação da troponina, mas sem SCA.

Abstract Background: Although non-ischemic troponin elevation is frequently seen in patients admitted to the emergency department (ED), consensus regarding its management is lacking. Objectives: This study aimed to characterize patients admitted to the ED with non-ischemic troponin elevation and to identify potential mortality predictors in this population. Methods: This retrospective observational study included ED patients with a positive troponin test result between June and July of 2015. Patients with a clinical diagnosis of acute coronary syndrome (ACS) were excluded. Data on patient demographics and clinical and laboratory variables were extracted from medical records. Follow-up data were obtained for 16 months or until death occurred. The statistical significance level was 5%. Results: Troponin elevation without ACS was found in 153 ED patients. The median (IQR) patient age was 78 (19) years, 80 (52.3%) were female and 59(38.6%) died during follow-up. The median (IQR) follow-up period was 477(316) days. Survivors were significantly younger 76 (24) vs. 84 (13) years; p=0.004) and featured a higher proportion of isolated troponin elevation (without creatine kinase or myoglobin elevation) in two consecutive evaluations: 48 (53.9%) vs. 8 (17.4%), p<0.001. Survivors also presented a lower rate of antiplatelet treatment and same-day hospitalization. In the multivariate logistic regression with adjustment for significant variables in the univariate analysis, isolated troponin elevation in two consecutive evaluations showed a hazard ratio= 0.43 (95%CI 0.17–0.96, p=0.039); hospitalization, previous antiplatelet treatment and age remained independently associated with mortality. Conclusions: Isolated troponin elevation in two consecutive measurements was a strong predictor of survival in ED patients with troponin elevation but without ACS.

https://doi.org/10.36660/abc.20190356 675 descargas

10.

Alagille Syndrome: An ultrafiltration dilema
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Abrantes, Catarina

; Furtado, Teresa

; Domingues, Patrícia

; Valério, Patrícia

; Felgueiras, Joana

; Assunção, José

; Vaz, Álvaro

Portuguese Journal of Nephrology & Hypertension

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Sep 2021, Volumen 35 Nº 3 Paginas 203 - 204

Resumen: En | Texto: En | PDF: En

ABSTRACT Alagille syndrome (AGLS) is a rare genetic disorder caused by mutations in the Notch signaling pathway. Multiple organ dysfunction is frequent despite phenotypic variability. We report the case of an AGLS patient with right heart failure and persistent fluid overload who started peritoneal ultrafiltration, without initial benefit. Possible pathophysiological mechanisms related to the underlying genetic condition, namely vascular abnormalities, that could help explain the poor ultrafiltration are provided, while other ultrafiltration failure causes are briefly discussed. New evidence is necessary for a better understanding of this syndrome in PD modality.

https://doi.org/10.32932/pjnh.2021.10.148 56 descargas

11.

Structure and nutritional value of BRS Zuri grass under shading
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JANUSCKIEWICZ, Estella Rosseto

; PAIVA, Luísa Melville

; FERNANDES, Henrique Jorge

; FLEITAS, Alex Coene

; DUARTE, Camila Fernandes Domingues

; BISERRA, Thiago Trento

; GOMES, Patrícia dos Santos

Revista Brasileira de Saúde e Produção Animal

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2021, Volumen 22 elocation e2122122021

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo foi determinar os parâmetros estruturais e de valor nutritivo do Panicum maximum cv. BRS Zuri sob sistema sombreado por eucalipto, nas estações chuvosa e seca. No começo de cada estação, os tratamentos (níveis de fertilização foliar de 0, 3, 6 and 9 L ha-1) foram aplicados e as avaliações realizadas aos 28, 56 e 84 dias de crescimento. Os tratamentos não afetaram significativamente (p ≥ 0.05) os parâmetros avaliados. Os sistemas (sombreado e a pleno sol) e estações não modificaram (p ≥ 0.05) as massas de forragem e de raízes. O conteúdo de proteína bruta foi maior (p ≤ 0.05) na estação seca. Altura, massas de folhas, colmos e material morto, conteúdos de fibra em detergente ácido e neutro, e digestibilidade in vitro da matéria seca foram significativamente afetados (p ≤ 0.05) pela interação sistema x estação. Os dias de crescimento não afetaram (p ≥ 0.05) a massa de forragem. A massa de material morto diminuiu (p ≤ 0.05) com os intervalos de avaliação. Os outros parâmetros foram afetados (p ≤ 0.05) pela interação sistema x dias de crescimento. Baseado nos resultados observados, as massas de forragem e raízes mostram que o cv. BRS Zuri é adaptado ao sombreamento proposto pelas condições experimentais. Essas massas, somadas ao conteúdo de proteína bruta indica que o capim é adaptado a baixas precipitações, inerentes a estação seca; a fertilização foliar aplicada no começo das estações não afeta os parâmetros estruturais e de valor nutritivo do capim BRS Zuri.

ABSTRACT The objective was to determine the structural and nutritive parameters for Panicum maximum cv. BRS Zuri under a Eucalyptus shading system, in rainy and dry seasons. At the beginning of each season, the treatments (foliar fertilization levels of 0, 3, 6 and 9 L ha-1) were applied and evaluated at 28, 56, and 84 growing days. The treatments did not affect significantly (p ≥ 0.05) the evaluated parameters. The systems (shading and full sun) and seasons did not change (p ≥ 0.05) forage and root masses. The leaf crude protein content was higher (p ≤ 0.05) in the dry season. Height, leaf mass, stem and dead material, neutral and acid detergent fiber contents, and in vitro dry matter digestibility were affected (p ≤ 0.05) by the system x season. The growing days did not affect (p ≥ 0.05) forage mass. The mass of dead material decreased (p ≤ 0.05) over the evaluated intervals. The other parameters were affected (p ≤ 0.05) by system × growing days. Based on the results, the forage and root masses show that the cv. BRS Zuri is adapted to the shading in the proposed experimental conditions. These masses added to the crude protein content indicate adaptation to low rainfall, inherent to the dry season, while foliar fertilization applied at the beginning of seasons did not affect the structural and nutritive parameters of BRS Zuri grass.

https://doi.org/10.1590/s1519-99402122122021 116 descargas

12.

Anthropogenic river fragmentation reduces long-term viability of the migratory fish Salminus brasiliensis (Characiformes: Bryconidae) populations
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Ribolli, Josiane

; Zaniboni-Filho, Evoy

; Machado, Carolina Barros

; Guerreiro, Tailise Carolina de Souza

; Freitas, Patrícia Domingues de

; Galetti Jr, Pedro Manoel

Neotropical Ichthyology

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2021, Volumen 19 Nº 2 elocation e200123

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo História de vida, barreiras geográficas e barramento dos rios podem moldar a diversidade genética de grandes peixes migratórios de água doce, que são particularmente vulneráveis a impactos antrópicos. Nós investigamos a diversidade genética de Salminus brasiliensis, uma espécie migratória de longa distância que é reconhecida como um importante provedor de serviços ecossistêmicos. Realizamos análises de microssatélites para avaliar a diversidade genética e simular cenários futuros, possibilitando estimar a viabilidade em longo prazo de populações situadas em regiões com e sem represas do rio Uruguai. Altos níveis de diversidade genética foram detectados para todas as populações amostradas. Contudo, os tamanhos populacionais efetivos foram menores nos trechos superiores do rio, onde a paisagem é altamente fragmentada. A análise da estrutura populacional indicou duas populações genéticas espaciais. Sugere-se que esta estrutura genética preserva populações parcialmente isoladas por uma antiga barreira natural, ao invés de ser resultado da presença de barragens. Os cenários genéticos simulados indicaram que a variabilidade genética das populações de S. brasiliensis situadas a montante das barragens entraria em colapso ao longo dos anos, principalmente como resultado da redução do número de alelos. Portanto, além de ajudar a entender melhor questões relacionadas à influência de barragens na diversidade genética de peixes migradores, nossos resultados são especialmente relevantes para a condução de políticas pesqueiras locais e ações de manejo para a conservação das espécies.

Abstract Life-history, geographical barriers, and damming can shape the genetic diversity of freshwater migratory fish, which are particularly vulnerable to anthropogenic impacts. We investigated the genetic diversity of Salminus brasiliensis, a long-distance migratory species that is recognized as an important provider of ecosystem services. We implemented microsatellite analyses to assess genetic diversity and simulate future scenarios for evaluating the long-term viability of dammed and non-dammed populations from the Uruguay River. High levels of genetic diversity were detected for all sampled populations. However, effective population sizes were lower in the uppermost river stretches, where the landscape is highly fragmented. Population structure analysis indicated two spatial genetic populations. It is suggested that this genetic structure preserves populations partially isolated by an ancient natural barrier, instead of being a result of the presence of dams. The simulated genetic scenarios indicated that genetic variability of S. brasiliensis populations from upstream dams could collapse over the years, mainly due to the reduction in the number of alleles. Therefore, besides helping to better understand issues related to the influence of dams on the genetic diversity of migratory fish, our results are especially relevant for driving local fishery policies and management actions for the species conservation.

https://doi.org/10.1590/1982-0224-2020-0123 141 descargas

13.

Diretriz Brasileira de Cardio-oncologia – 2020
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Hajjar, Ludhmila Abrahão

; Costa, Isabela Bispo Santos da Silva da

; Lopes, Marcelo Antônio Cartaxo Queiroga

; Hoff, Paulo Marcelo Gehm

; Diz, Maria Del Pilar Estevez

; Fonseca, Silvia Moulin Ribeiro

; Bittar, Cristina Salvadori

; Rehder, Marília Harumi Higuchi dos Santos

; Rizk, Stephanie Itala

; Almeida, Dirceu Rodrigues

; Fernandes, Gustavo dos Santos

; Beck-da-Silva, Luís

; Campos, Carlos Augusto Homem de Magalhães

; Montera, Marcelo Westerlund

; Alves, Sílvia Marinho Martins

; Fukushima, Júlia Tizue

; Santos, Maria Verônica Câmara dos

; Negrão, Carlos Eduardo

; Silva, Thiago Liguori Feliciano da

; Ferreira, Silvia Moreira Ayub

; Malachias, Marcus Vinicius Bolivar

; Moreira, Maria da Consolação Vieira

; Valente Neto, Manuel Maria Ramos

; Fonseca, Veronica Cristina Quiroga

; Soeiro, Maria Carolina Feres de Almeida

; Alves, Juliana Barbosa Sobral

; Silva, Carolina Maria Pinto Domingues Carvalho

; Sbano, João

; Pavanello, Ricardo

; Pinto, Ibraim Masciarelli F.

; Simão, Antônio Felipe

; Dracoulakis, Marianna Deway Andrade

; Hoff, Ana Oliveira

; Assunção, Bruna Morhy Borges Leal

; Novis, Yana

; Testa, Laura

; Alencar Filho, Aristóteles Comte de

; Cruz, Cecília Beatriz Bittencourt Viana

; Pereira, Juliana

; Garcia, Diego Ribeiro

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

; Macedo, Ariane Vieira Scarlatelli

; Marcatti, Patricia Tavares Felipe

; Mathias Junior, Wilson

; Wiermann, Evanius Garcia

; Val, Renata do

; Freitas, Helano

; Coutinho, Anelisa

; Mathias, Clarissa Maria de Cerqueira

; Vieira, Fernando Meton de Alencar Camara

; Sasse, André Deeke

; Rocha, Vanderson

; Ramires, José Antônio Franchini

; Kalil Filho, Roberto

Arquivos Brasileiros de Cardiologia

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Nov 2020, Volumen 115 Nº 5 Paginas 1006 - 1043

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201006 4180 descargas

14.

Infra-Abdominal Muscles Activation Brings Benefits to the Pulmonary Function of Patients with Sternal Instability after Cardiac Surgery
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Nozawa, Emilia

; Gonçalves, Cristiane Domingues

; Almeida, Patricia Oliva de

; Hajjar, Ludhmila Abrahão

; Galas, Filomena Regina Gomes

; Feltrim, Maria Ignêz Zanetti

Brazilian Journal of Cardiovascular Surgery

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Ene 2020, Volumen 35 Nº 1 Paginas 141 - 149

Resumen: En | Texto: En | PDF: En

Abstract Objective: To compare physical therapy strategies involving abdominal muscle stabilization, with and without upper limb movement, in patients with sternal instability after heart surgery and during in-hospital care. Methods: This prospective, longitudinal, randomized, and comparative clinical study included 20 patients, which were divided into two groups: ARM, the arm group (n=10), and LEG, the leg group (n=10). The study involved the evaluation of scores of visual analog scales for sternal instability, pain, discomfort, functional impairment, lung function, and maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) before and after the interventions. Two protocols consisting of abdominal exercises in both groups with upper limb movements (ARM) and just abdominal activation with leg movements (LEG) were used for three weeks. Results: There were statistically significant (P≤0.01) improvements in pain, discomfort, and functional impairment scores, and in MIP (P=0.04) and MEP (P≤0.01) after intervention in both groups and just LEG showed improvement in forced vital capacity (P=0.043) and forced expiratory volume in one second (P=0.011). Conclusion: Both strategies promoted improvement in pain, discomfort, and functional impairment scores and in the values of inspiratory and expiratory pressures. Perhaps they were influenced by the time and resolution of the infection process, although exercises with upper limb movements seem to be safe in this population. The activation of the infra-abdominal muscles through leg movements seems to bring more benefits to lung function.

https://doi.org/10.21470/1678-9741-2018-0365 376 descargas

15.

Performance and development of gastric compartments of calves fed with cheese whey and transition milk
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Miranda, Maria Vivianne Freitas Gomes de

; Morais, Michel Raony Paiva Teixeira de

; Lima, Renata Nayhara de

; Leite, Hélia Maria de Souza

; Assis, Ana Paula Pinheiro de

; Teófilo, Tiago da Silva

; Fontenele Neto, José Domingues

; Lima, Patrícia de Oliveira

Ciência Rural

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2019, Volumen 49 Nº 9 elocation e20190308

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivou-se avaliar se o soro de queijo associado ou não ao leite de transição poderia servir como uma alternativa adequada ao leite integral para a criação de bezerros. Para isso, 24 bezerros machos, mestiços Holandês-Zebu, foram distribuídos em delineamento inteiramente casualizado com três tratamentos (oito bezerros por tratamento) e alimentados por 60 dias com uma das seguintes dietas líquidas: i) 100% leite integral; ii) 50% de leite integral e 50% de soro de queijo, e iii) 30% de leite de transição e 70% de soro de queijo. Não houve diferença na ingestão de alimentos entre os tratamentos. A análise mostrou que a substituição do leite integral não alterou o peso do estômago ou a proliferação das células ruminais quando comparado ao tratamento com 100% de leite integral. No entanto, o grupo de soro de queijo/leite de transição mostrou papilas ruminais maiores. Esses resultados sugerem que uma dieta de soro de queijo com leite de transição associada a alimentos sólidos e a complementos nutricionais apropriados pode aumentar o desenvolvimento pós-natal de papilas no rúmen de bezerros, o que pode contribuir para prepará-los para o desmame.

ABSTRACT: This study aimed to evaluate whether cheese whey associated with transitional milk or not, could serve as a suitable alternative to whole milk for calf rearing. For this, twenty-four male calves of crossbred Holstein-Zebu, were distributed in a completely randomized design with three treatments (8 calves per treatment) and fed for 60 days with one of the following liquid diets: i) 100% whole milk, ii) 50% whole milk and 50% cheese whey, and iii) 30% transitional milk and 70% cheese whey. There was no difference in food intake between treatments. The analysis showed that whole milk replacement did not alter the stomach weight or the ruminal cell proliferation when compared to treatment using 100% whole milk; however, the transitional milk/cheese whey group showed larger ruminal papillae. These results suggested that a transitional milk-cheese whey diet associated with solid food and proper nutrient complements might enhance the post-natal development of rumen papillae in calves, which might contribute to prepare them for weaning.

https://doi.org/10.1590/0103-8478cr20190308 916 descargas

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