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ABSTRACT Objective To describe the personal protective equipment training strategies during the beginning of the pandemic and to investigate the association between training and COVID-19 infection among healthcare workers. Methods This cross-sectional study conducted between March and May 2020 included 7,142 healthcare professionals who were eligible for both online and face-to-face simulation-based training on personal protective equipment use. Simulation training attendance was assessed by reviewing the attendance list, and the COVID-19 sick leave records recovered from the institutional RT-PCR database used to grant sick leave. The association between personal protective equipment training and COVID-19 was investigated using logistic regression, adjusted for sociodemographic and occupational characteristics. Results The mean age was 36.9 years (± 8.3), and 72.6% of participants were female. A total of 5,502 (77.0%) professionals were trained: 3,012 (54.7%) through online training, 691 (12.6%) through face-to-face training, and 1,799 (32.7%) through both strategies. During the study period, 584 (8.2%) COVID-19 cases were diagnosed among these professionals. The number of positive RT-PCR tests was 180 (11.0%) for untrained professionals, 245 (8.1%) for those trained only online, 35 (5.1%) for those trained face-to-face, and 124 (6.9%) for those trained with both strategies (p<0.001). Participants who received face-to-face training had a 0.43 lower risk of contracting COVID-19. Conclusion Personal protective equipment training decreased the odds of COVID-19 among healthcare professionals, with face-to-face simulation-based training being most effective.

https://doi.org/10.31744/einstein_journal/2023ao0300

Isolation and Characterization of Plant Growth-Promotion Diazotrophic Endophytic Bacteria Associated to Sugarcane (Saccharum officinarum L.) Grown in Paraíba, Brazil
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Antunes, Jadson Emanuel Lopes

; Freitas, Ana Dolores Santiago de

; Bonifacio, Aurenivia

; Oliveira, Louise Melo de Souza

; Santos, Carolina Etienne de Rosália e Silva

; Lyra, Maria do Carmo Catanho Pereira de

; Oliveira, José de Paula

; Ollero, Francisco Javier

; Araújo, Ademir Sérgio Ferreira de

; Figueiredo, Marcia do Vale Barreto

Brazilian Archives of Biology and Technology

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2022, Volumen 65 elocation e22200439

Resumen: En | Texto: En | PDF: En

Abstract: Sugarcane is an important Brazilian commodity, being usually cultivated in soils with low natural fertility. This study aimed to isolate diazotrophic endophytes from sugarcane tissues and evaluate the morphological and physiological characteristics of their colonies as well as their plant growth-promoting (PGP) traits in select diazotrophic endophytic bacteria. Fifty-six bacterial isolates were identified in the sugarcane tissues, and these isolates presented distinct morphological and physiological traits. A total of thirty-five bacterial isolates were biochemically evaluated. Overall, Bacillus was the dominant genus. Isolates of Methylobacterium spp. and Brevibacillus agri were present only in leaves, while Herbaspirillum seropedicae occurred only in stems. Except to IPA-CF45A, all isolates were nitrogenase positive. All endophytes exhibit production of indol 3-acetic acid. Over 50% of endophytes solubilize phosphate, release N-acyl homoserine lactones, and present the activity of 1-aminocyclopropane-1-carboxylic acid deaminase, catalase, lipase and protease. The network analysis showed that isolates belonged to Burkholderia, Herbaspirillum, and Methylobacterium interact with Bacillus. Bacterial endophytes exhibited distinct morphological, physiological, and PGP traits that are useful for sustainable agriculture, highlighting the isolates IPA-CC33, IPA-CF65, IPA-CC9 and IPA-CF27. Further studies on the effects of these diazotrophic endophytes and their potential for providing microbial inoculants for improving sugarcane fields will provide valuable information to maintain the sustainability and environment quality.

https://doi.org/10.1590/1678-4324-2022200439

Minimally Invasive Osteosynthesis of Transtrochanteric Fractures with Dynamic Hip Screw (DHS)
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Guimarães, José André Melo Barreto

; Machado, Marcos Cezar Feitosa de Paula

; Galvão, Pauliana Valéria Machado

; Lima, Jéssika Cristina de

; Gomes, Lucas dos Santos

; Guimarães, Pedro Ferreira Barreto

Revista Brasileira de Ortopedia

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Feb 2021, Volumen 56 Nº 1 Paginas 109 - 113

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O método aqui apresentado consiste em técnica cirúrgica minimamente invasiva para osteossíntese de fraturas transtrocantéricas com Dynamic Hip Screw (DHS) 135º. Esta técnica é indicada no tratamento de fraturas 31-A1 e 31-A2 (Classificação Arbeitsgemeinschaft für Osteosynthesefragen - AO) que cumpram os pré-requisitos exigidos para o uso do DHS. A cirurgia é realizada, preferencialmente, antes de 48 horas após o acometimento da fratura. Com a utilização do mesmo instrumental da técnica cirúrgica tradicional e auxílio do arco-C, realiza-se redução incruenta da fratura e implantação do DHS por incisão cirúrgica com 2 cm, através de dissecção dos tecidos subjacentes, com mínimo sangramento e agressão às partes moles. No pós-operatório imediato, o paciente é estimulado ao ortostatismo e à deambulação com carga total, o que antecipa a alta hospitalar e favorece a reabilitação funcional precoce. O retorno ambulatorial é agendado com 2, 6, 12 e 24 semanas de pós-operatório, com avaliação radiográfica, a fim de avaliar a consolidação da fratura.

Abstract The method presented here consists of a minimally invasive surgical technique for osteosynthesis of transtrochanteric fractures with Dynamic Hip Screw (DHS) 135º. It is indicated in the treatment of 31-A1 and 31-A2 fractures (Arbeitsgemeinschaft für Osteosynthesefragen Classification - AO) that meet the prerequisites required for using DHS. The surgery is performed, preferably, before 48 hours after the fracture. With the use of the same instruments as the traditional surgical technique and the aid of the C-arm, a closed reduction of the fracture and implantation of the DHS is performed by a 2-cm surgical incision, through dissection of the underlying tissues, with minimal bleeding and damage to the soft parts. In the immediate postoperative period, the patient is encouraged to orthostatism and walk with full load, which anticipates hospital discharge and favors early functional rehabilitation. Outpatient return is scheduled at 2, 6, 12 and 24 weeks postoperatively, with radiographic evaluation to assess fracture healing.

https://doi.org/10.1055/s-0040-1716758 310 descargas

Irrigation system with ultra low flow using branched microtubes
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Alves, Dinara Grasiela

; Ferreira Pinto, Marinaldo

; Alves Barreto Damasceno, Ana Paula

; Salvador, Conan Ayade

; Duarte Guedes Cabral de Almeida, Ceres

; Botrel, Tarlei Arriel

DYNA

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Mar 2020, Volumen 87 Nº 212 Paginas 277 - 283

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Con el objetivo de desarrollar un sistema de irrigación con ultra baja caudal (UBV) de 0,2 L h-1, utilizando microtubos con derivación y operando en régimen laminar, se inició este trabajo buscando irrigación eficiente y de bajo costo. El experimento se compuso de dos etapas. La primera parte experimental fue conducida en el laboratorio, siendo realizada la determinación del diámetro real de los microtubos y dimensionamiento del sistema de riego. La segunda etapa del experimento fue realizada en una huerta ubicada en el área experimental, donde se realizaron los ensayos para obtener la uniformidad de aplicación de agua a la cual fue evaluada por medio del coeficiente de uniformidad estadística que tuvo valor inicial superior a 90%. El sistema de riego propuesto presentó ventajas económicas para pequeños productores. Sin embargo, el mismo presentó problemas de acumulación de aire y obstrucción de emisores durante el período evaluado, ocasionando la reducción de la uniformidad estadística siendo, por lo tanto, necesaria la realización de más estudios para obtener resultados más concluyentes.

Abstract With the goal of developing an irrigation system with ultra low flow rate (ULF) of 0.2 L h-1, using microtubes with derivation and operating in a laminar regime, this work began by seeking efficient irrigation and low costs. The experiment consisted of two stages. The first experiment was conducted in the laboratory to determine the actual diameter of the microtubes and irrigation system design. The second stage of the experiment was conducted in an experimental area, where tests were carried out to obtain the uniformity of water application which was evaluated by the coefficient of uniformity statistic that had an initial value exceeding 90%. The proposed irrigation system had economic advantages for small-scale producers. However, the system evaluated presented problems with accumulation of air and emitters obstruction during the study period, causing a reduction in statistical uniformity. It is therefore necessary to conduct further studies to obtain more conclusive results.

https://doi.org/10.15446/dyna.v87n212.71947 182 descargas

Aggressive papillary thyroid carcinoma in a child with type 2 congenital generalized lipodystrophy
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Lima, Grayce Ellen da Cruz Paiva

; Fernandes, Virgínia Oliveira

; Montenegro, Ana Paula Dias Rangel

; Carvalho, Annelise Barreto de

; Karbage, Lia Beatriz de Azevedo Sousa

; Aguiar, Lindenberg Barbosa

; Macedo, Mário Sérgio Rocha

; Ferreira, Luis Alberto Albano

; Montenegro Júnior, Renan Magalhães

Archives of Endocrinology and Metabolism

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Ene 2019, Volumen 63 Nº 1 Paginas 79 - 83

Resumen: En | Texto: En | PDF: En

SUMMARY Thyroid carcinoma (TC) is rare in children, particularly in those aged < 10 years. Several studies have demonstrated a correlation between neoplasms and hyperinsulinemia and insulin resistance, which are often associated with a higher risk for and/or aggressiveness of the neoplasm. Congenital generalized lipodystrophy (CGL) with autosomal recessive inheritance is a rare disease and is characterized by the lack of adipose tissue, severe insulin resistance, and early metabolic disturbances. Here, we reported a rare case of a type 2 CGL in a girl who presented with a papillary TC (PTC) at the age of 7 years. She had no family history of TC or previous exposure to ionizing radiation. She had a generalized lack of subcutaneous fat, including the palmar and plantar regions, muscle hypertrophy, intense acanthosis nigricans, hepatomegaly, hypertriglyceridemia, severe insulin resistance, and hypoleptinemia. A genetic analysis revealed a mutation in the BSCL2 gene (p.Thr109Asnfs* 5). Ultrasound revealed a hypoechoic solid nodule measuring 1.8 × 1.0 × 1.0 cm, and fine needle aspiration biopsy suggested malignancy. Total thyroidectomy was performed, and a histopathological examination confirmed PTC with vascular invasion and parathyroid lymph node metastasis (pT3N1Mx stage). This is the first report to describe a case of differentiated TC in a child with CGL. Severe insulin resistance that is generally observed in patients with CGL early in life, especially in those with type 2 CGL, may be associated with this uncommon presentation of aggressive PTC during childhood.

https://doi.org/10.20945/2359-3997000000096 1086 descargas

Pigmented Kamino bodies: a little-known histological finding. Prevalence in 19 cases of Reed nevus
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Antunes, Ana Caroline Barreto

; Véspoli, Aline Caixeta Guimarães

; Ferreira, Paula Silva

; Valente, Neusa Yuriko Sakai

Anais Brasileiros de Dermatologia

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Jun 2017, Volumen 92 Nº 3 Paginas 379 - 382

Resumen: En | Texto: En | PDF: En

Abstract The present study aimed to determine the prevalence of Kamino bodies in Reed nevus, since most studies to date show conflicting data on this issue. This was a retrospective observational study, in which the histopathology of 19 Reed nevus lesions were reviewed. The slides were stained by hematoxylin and eosin and periodic acid-Schiff, with a special focus placed on the identification of Kamino bodies. Some clinical data were also collected. The median patient age was 12 years (range of 2 to 58). The women to men ratio was 5:4. Lesions were located on different parts of the body. Kamino bodies were found in eleven lesions (57.89%). five showed pigmented Kamino bodies (26.31%), four non-pigmented Kamino bodies (21,05%), and 2 (10.52%) had both. Kamino bodies, pigmented or not, are a common histological finding in Reed nevus and may well represent a good marker to differentiate these from malignant melanomas.

https://doi.org/10.1590/abd1806-4841.20175996 1711 descargas

Microbial investigation of biofilms recovered from endotracheal tubes using sonication in intensive care unit pediatric patients
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Ferreira, Thiago de Oliveira

; Koto, Rafael Yoshio

; Leite, Gabriel Fialkovitz da Costa

; Klautau, Giselle Burlamaqui

; Nigro, Stanley

; Silva, Cely Barreto da

; Souza, Ana Paula Idalgo da Fonseca

; Mimica, Marcelo Jenne

; Cesar, Regina Grigolli

; Salles, Mauro José Costa

Brazilian Journal of Infectious Diseases

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Oct 2016, Volumen 20 Nº 5 Paginas 468 - 475

Resumen: En | Texto: En | PDF: En

Abstract Objectives To compare cultured microorganisms identified on endotracheal tubes biofilms through sonication technique with traditional tracheal aspirate collected at extubation of pediatric intensive care unit patients. Methods Demographic and epidemiological data were analyzed to identify factors possibly related with the microbiological profile of the two collection methods. Associations between categorical and continuous variables were analyzed using the chi-square or Fisher's exact test, or Student's t test. p-Value <0.05 were considered significant. Results Thirty endotracheal tubes and tracheal aspirates samples from 27 subjects were analyzed. Only one patient presented the clinical diagnosis of ventilator-associated pneumonia. Overall, 50% of bacteria were Gram-negative bacilli, followed by Gram-positive bacteria in 37%, and fungi in 10%. No statistically significant difference on the distribution of Gram-positive or Gram-negative bacteria (p = 0.996), and fungi (p = 0.985) were observed between the collection methods. Pseudomonas spp. was the most frequent microorganism identified (23.8%), followed by Streptococcus spp. (18.5%), Acinetobacter spp. (15.9%), coagulase-negative staphylococci (11.2%), and Klebsiella spp. (8.6%). Concordant results between methods amounted to 83.3%. Pseudomonas aeruginosa and Acinetobacter baumannii showed carbapenem resistance in 50% and 43.7% of the isolates, respectively. In general, cultures after endotracheal tubes sonication (non-centrifuged sonication fluid and centrifuged sonication fluid) yielded bacteria with higher rates of antimicrobial resistance compared to tracheal aspirates cultures. Additionally, in 12 subjects (40%), we observed discrepancies regarding microbiologic profiles of cultures performed using the collection methods. Conclusions Our study demonstrated that sonication technique can be applied to ET biofilms to identify microorganisms attached to their surface with a great variety of species identified. However, we did not find significant differences in comparison with the traditional tracheal aspirate culture approach.

https://doi.org/10.1016/j.bjid.2016.07.003 859 descargas

Software CMAP TOOLS® para a construção de mapas conceituais: a avaliação dos estudantes de enfermagem
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Ferreira, Paula Barreto

; Cohrs, Cibelli Rizzo

; De Domenico, Edvane Birelo Lopes

Revista da Escola de Enfermagem da USP

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Ago 2012, Volumen 46 Nº 4 Paginas 967 - 972

Resumen: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

O mapeamento conceitual (MC) é uma estratégia de ensino que pode ser utilizada para resoluções de casos clínicos, porém de trabalhosa execução manuscrita. O estudo teve por objetivos descrever os desafios e as contribuições do software Cmap Tools® para a construção de mapas conceituais para resolução de caso clínico. Para isso, utilizou-se método descritivo, qualitativo, com estudantes da 3ª série de Graduação em Enfermagem da Universidade Federal de São Paulo. A estratégia de ensino foi aplicada e os dados foram coletados pela técnica do grupo focal. Os resultados evidenciaram que o software facilita e garante a organização, visualização e correlação dos dados, porém com dificuldades iniciais relacionadas ao manejo das ferramentas que dispõe. Concluiu-se que o software Cmap Tools® favoreceu a construção dos MC por seus recursos de formatação e autoformatação e que estratégias de orientação deveriam ser implantadas para a fase inicial de utilização.

Concept mapping (CM) is a teaching strategy that can be used to solve clinical cases, but the maps are difficult to write. The objective of this study was to describe the challenges and contributions of the Cmap Tools® software in building concept maps to solve clinical cases. To do this, a descriptive and qualitative method was used with junior nursing students from the Federal University of São Paulo. The teaching strategy was applied and the data were collected using the focal group technique. The results showed that the software facilitates and guarantees the organization, visualization, and correlation of the data, but there are difficulties related to the handling of its tools initially. In conclusion, the formatting and auto formatting resources of Cmap Tools® facilitated the construction of concept maps; however, orientation strategies should be implemented for the initial stage of the software utilization.

El mapeo conceptual (MC) es una estrategia de enseñanza que puede utilizarse para resolución de casos clínicos, más allá de su trabajosa ejecución manual. Se objetivó describir los desafíos y contribuciones del software CMAP Tools® para la construcción de mapas conceptuales enfocados a resolución de casos clínicos. Metodología descriptiva, cuantitativa, con estudiantes de tercer año de Enfermería de la Universidad Federal de São Paulo. Se aplicó estrategia de enseñanza, datos recolectados mediante técnica del grupo focal. Los resultados evidenciaron que el software facilita y garantiza la organización, visualización y correlación de datos, aunque con dificultades iniciales relacionadas al manejo de las herramientas de las que dispone. Se concluye en que el software CMAP Tools® facilitó la construcción de MC por sus recursos de formateo y auto-formateo, y que deberían implantarse estrategias de orientación para la fase inicial de utilización.

7583 descargas Citado 2 veces en SciELO

Software CMAP TOOLS® para a construção de mapas conceituais: a avaliação dos estudantes de enfermagem
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Ferreira, Paula Barreto

; Cohrs, Cibelli Rizzo

; De Domenico, Edvane Birelo Lopes

Revista da Escola de Enfermagem da USP

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Ago 2012, Volumen 46 Nº 4 Paginas 967 - 972

Resumen: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

4 descargas Citado 2 veces en SciELO

10.

Triple inoculation with Bradyrhizobium, Glomus and Paenibacillus on cowpea (Vigna unguiculata [L.] walp.) development
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Lima, André Suêldo Tavares de

; Xavier, Terezinha Ferreira

; Lima, Cláudia Elizabete Pereira de

; Oliveira, José de Paula

; Mergulhão, Adália Cavalcanti do Espírito Santo

; Figueiredo, Márcia do Vale Barreto

Brazilian Journal of Microbiology

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Sep 2011, Volumen 42 Nº 3 Paginas 919 - 926

Resumen: En | Texto: En | PDF: En

The use of microorganisms to improve the availability of nutrients to plants is of great importance to agriculture. This study aimed to evaluate the effect of triple inoculation of cowpea with arbuscular mycorrhizal fungi (AMF), plant growth-promoting bacteria (PGPB) and rhizobia to maximize biological nitrogen fixation (BNF) and promote plant growth. The experiment was conducted in a greenhouse using cowpea plants (Vigna unguiculata L. Walp cv. IPA 206). The treatments included inoculation with strains of Bradyrhizobium sp. (BR 3267 and EI - 6) individually and as a mixture, an absolute control (AC) and mineral nitrogen control (NC), all combined with the presence or absence of native AMF (Glomus etunicatum) and PGPB (Paenibacillus brasilensis - 24) in a 5x2x2 factorial design. All treatments were replicated three times. Contrasts were performed to study the treatment of variables. Inoculation with Bradyrhizobium sp. (BR 3267 and EI - 6) and G. etunicatum favored nitrogen acquisition and phosphorus availability for the cowpea plants. Inoculation with P. brasilensis - 24 increased colonization by Bradyrhizobium sp. and G. etunicatum and promoted cowpea growth, while the nitrogen from symbiosis was sufficient to supply the plants nutritional needs.

2815 descargas Citado 1 vez en SciELO

11.

Classification of journals in the QUALIS System of CAPES URGENT need of changing the criteria!
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Andriolo, Adagmar

; Souza, Aécio Flávio Meireles

; Farias, Alberto Queiroz

; Barbosa, Alfredo José Afonso

; França Netto, Antonio Spina

; Hernandez, Arnaldo José

; Camargos, Aroldo F.

; Barraviera, Benedito

; Kadunc, Bogdana Victoria

; Caramelli, Bruno

; Campos, Carlos Eduardo Aguilera

; Brites, Carlos

; Nascimento, Dejair Caitano do

; Braile, Domingo M.

; Goldenberg, Dov Charles

; Baracat, Edmund Chada

; Kimura, Edna T.

; Marchiori, Edson

; Vieira, Eduardo de Paula

; Almeida, Eros Antônio de

; Jotz, Geraldo Pereira

; Camanho, Gilberto

; Friedman, Gilberto

; Cerri, Giovanni Guido

; Duarte, Ivomar Gomes

; Costa, Izelda Maria Carvalho

; Mello Júnior, João Ferreira de

; Faintuch, Joel

; Martinez, José Antônio Baddini

; Antonio Livramento, José

; Manso, José Eduardo Ferreira

; Amaral, José Luiz Gomes do

; Battistella, Linamara Rizzo

; Machado, Luís dos Ramos

; Moreira, Luiz Felipe P.

; Gebrim, Luiz Henrique

; Madeira, Marcelo

; Riberto, Marcelo

; Bastos, Marcus

; Falcão, Mário Cícero

; Conceição, Mario J. da

; Silva, Mauricio Rocha e

; Ruiz, Milton Artur

; Shibata, Milton K.

; Santiago, Mittermayer Barreto

; Andreollo, Nelson Adami

; Malafaia, Osvaldo

; Martins, Regina Helena Garcia

; Procianoy, Renato Soibelmann

; Baroudi, Ricardo

; Fuller, Ricardo

; Viebig, Ricardo Guilherme

; Nitrini, Ricardo

; Moura, Rita Cristina Mainieri R. de

; Dedivitis, Rogério

; Damião, Ronaldo

; Lianza, Sergio

; Rode, Sigmar de Mello

; Yoshida, Winston Bonetti

; Handar, Zuher

Arquivos de Neuro-Psiquiatria

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Abr 2010, Volumen 68 Nº 2 Paginas 327 - 329

Resumen: En | Texto: En | PDF: En

3236 descargas Citado 9 veces en SciELO

12.

Classificação dos Periódicos no Sistema QUALIS da CAPES - a Mudança dos Critérios é URGENTE!
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Andriolo, Adagmar

; Souza, Aécio Flávio Meireles

; Farias, Alberto Queiroz

; Barbosa, Alfredo José Afonso

; França Netto, Antonio Spina

; Hernandez, Arnaldo José

; Camargos, Aroldo F.

; Barraviera, Benedito

; Kadunc, Bogdana Victoria

; Caramelli, Bruno

; Campos, Carlos Eduardo Aguilera

; Brites, Carlos

; Nascimento, Dejair Caitano do

; Braile, Domingo M.

; Goldenberg, Dov Charles

; Kimura, Edna T

; Marchiori, Edson

; Vieira, Eduardo de Paula

; Almeida, Eros Antônio de

; Jotz, Geraldo Pereira

; Camanho, Gilberto

; Friedman, Gilberto

; Cerri, Giovanni Guido

; Duarte, Ivomar Gomes

; Costa, Izelda Maria Carvalho

; Mello Júnior, João Ferreira de

; Faintuch, Joel

; Martinez, José Antônio Baddini

; Livramento, José Antonio

; Manso, José Eduardo Ferreira

; Battistella, Linamara Rizzo

; Machado, Luís dos Ramos

; Moreira, Luiz Felipe P.

; Gebrim, Luiz Henrique

; Madeira, Marcelo

; Riberto, Marcelo

; Bastos, Marcus

; Falcão, Mário Cícero

; Conceição, Mario J. da

; Rocha e Silva, Mauricio

; Ruiz, Milton Artur

; Shibata, Milton K.

; Santiago, Mittermayer Barreto

; Andreollo, Nelson Adami

; Malafaia, Osvaldo

; Martins, Regina Helena Garcia

; Procianoy, Renato Soibelmann

; Baroudi, Ricardo

; Fuller, Ricardo

; Viebig, Ricardo Guilherme

; Nitrini, Ricardo

; Moura, Rita Cristina Mainieri R. de

; Dedivitis, Rogério

; Damião, Ronaldo

; Lianza, Sergio

; Rode, Sigmar de Mello

; Yoshida, Winston Bonetti

; Handar, Zuher

Arquivos Brasileiros de Cardiologia

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Mar 2010, Volumen 94 Nº 3 Paginas 290 - 291

Resumen: Pt | Texto: Pt | PDF: Pt

3995 descargas Citado 2 veces en SciELO

13.

Classificação dos periódicos no Sistema Qualis da Capes: a mudança dos critérios é urgente!
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Andriolo, Adagmar

; Barbosa, Alfredo José Afonso

; França Netto, Antonio Spina

; Hernandez, Arnaldo José

; Camargos, Aroldo F.

; Barraviera, Benedito

; Kadunc, Bogdana Victoria

; Caramelli, Bruno

; Campos, Carlos Eduardo Aguilera

; Brites, Carlos Roberto

; Braile, Domingo M.

; Goldenberg, Dov Charles

; Kimura, Edna T

; Marchiori, Edson

; Vieira, Eduardo de Paula

; Sampaio, Francisco J. B.

; Jotz, Geraldo Pereira

; Camanho, Gilberto

; Friedman, Gilberto

; Cerri, Giovanni Guido

; Duarte, Ivomar Gomes

; Costa, Izelda Maria Carvalho

; Mello Júnior, João Ferreira de

; Faintuch, Joel

; Martinez, José Antônio Baddini

; Livramento, José Antonio

; Manso, José Eduardo Ferreira

; Battistella, Linamara Rizzo

; Machado, Luís dos Ramos

; Moreira, Luiz Felipe P.

; Gebrim, Luiz Henrique

; Madeira, Marcelo

; Riberto, Marcelo

; Bastos, Marcus

; Falcão, Mário Cícero

; Silva, Mauricio Rocha e

; Ruiz, Milton Artur

; Shibata, Milton K.

; Santiago, Mittermayer Barreto

; Martins, Regina Helena Garcia

; Procianoy, Renato Soibelmann

; Baroudi, Ricardo

; Fuller, Ricardo

; Viebig, Ricardo Guilherme

; Nitrini, Ricardo

; Dedivitis, Rogério

; Damião, Ronaldo

; Lianza, Sergio

; Rode, Sigmar de Mello

; Yoshida, Winston Bonetti

; Handar, Zuher

Revista Brasileira de Hematologia e Hemoterapia

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Feb 2010, Volumen 32 Nº 1 Paginas 1 - 3

Resumen: Pt | Texto: Pt | PDF: Pt

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14.

Anticoagulação oral em pacientes com fibrilação atrial: das diretrizes à prática clínica
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Macedo, Paula Gonçalves

; Ferreira Neto, Eustáquio

; Silva, Bruno Toscani da

; Barreto Filho, José Roberto

; Maia, Henrique

; Novakoski, Clarissa

; Zanatta, André

; Oliveira, Edna Marques de

; Rocha, Jairo Macedo da

; Seixas, Tamer Najar

; Peres, Ayrton Klier

; Leite, Luiz

Revista da Associação Médica Brasileira

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2010, Volumen 56 Nº 1 Paginas 56 - 61

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

OBJETIVO: Apesar da anticoagulação oral (ACO) ter benefício comprovado em pacientes com fibrilação atrial (FA) e fatores de risco embólico, ela vem sendo subutilizada. O objetivo desse estudo foi avaliar a adequação da terapêutica anticoagulante em pacientes com FA acompanhados em clínica especializada em cardiologia, privada, de acordo com as diretrizes das sociedades americana e europeia de cardiologia de 2006 e a diretriz da Sociedade Brasileira de Cardiologia (SBC) de 2003. MÉTODOS: No período de novembro/2005 a agosto/2006 foram avaliados 7.486 eletrocardiogramas e selecionados 53 pts com laudo de FA e informações claras relatadas em prontuário sobre fatores de risco embólico e terapêutica de ACO. RESULTADOS: Dentre os 53 pacientes incluídos (68±16 anos; 29 homens - 55%), 25 (48%) tinham HAS, 20 (38%) insuficiência cardíaca e 3 (6%) DM. Dentre os 15 pacientes com alto risco embólico, 13 (86%) estavam em uso de ACO. De acordo com a recomendação das diretrizes americana e europeia: 32 (60%) pacientes tinham indicação Classe I, 17 (32%) Classe IIa, 1 (2%) Classe IIb e 3 (6%) Classe III. Estavam adequadamente tratados 21 (66%) pacientes da Classe I e 13 (76%) pacientes Classe IIa. Nesse subgrupo, 7/19 (37%) pacientes com idade >75 anos estavam sendo anticoagulados, comparado a 22/30 (73%) daqueles com idade inferior (p=0,016). Dentre os três pacientes com indicação Classe III, um estava incorretamente com prescrição de anticoagulante. Pela diretriz da SBC, 33 (62%) recebiam terapêutica antitrombótica adequada. Não houve diferença na utilização correta de ACO, comparando-se a diretriz brasileira e diretrizes americana e europeia (55% vs. 55%). CONCLUSÃO: A terapêutica anticoagulante está sendo prescrita adequadamente na maioria dos pacientes com FA, embora esse índice ainda esteja muito aquém do ideal, principalmente no contexto de uma clínica especializada em cardiologia. Isso é ainda mais grave no grupo de idosos.

OBJECTIVE: Although oral anticoagulation has proved beneficial for patients with atrial fibrillation (AF) and embolic risk factors, it is still underused. The objective of this study was to evaluate the adequacy of anticoagulation therapy in patients with AF followed in a private clinic specialized in cardiology, in accordance with the American and European societies of cardiology guidelines/2006 and with the Brazilian Guidelines/2003. METHODS: Between November 2005 and August 2006, we evaluated 7,486 electrocardiograms and selected 53 patients with AF and complete chart records. Clinical characteristics, including embolic risk factor, echocardiographic data and medical treatment were reviewed. RESULTS: Among the 53 patients (68±16 years; 29 men), 25 (48%) had hypertension, 20 (38%) heart failure and 3 (6%) diabetes. Among the 15 patients with high embolic risk, 13 (86%) were on oral anticoagulation. In accordance with the American and European guidelines: 32 (60%) patients were Class I, 17 (32%) Class IIa, 1 (2%) Class IIb and 3 (6%) Class III. Treatment was adequate in 21 (66%) Class I patients and 13 (76%) Class IIa. In these, anticoagulation therapy was used in 7/19 (37%) patients > 75 years compared to 22/30 (73%) younger. Among the 3 patients within Class III, 1 was incorrectly on OAC. According to Brazilian guidelines, 33 (62%) were on correctly indicated antithrombotic therapy. There was no difference in the appropriate prescription of oral anticoagulants, comparing the international and Brazilian guidelines (55% vs. 55%). CONCLUSION: According to recent guidelines, anticoagulant therapy has been adequately prescribed for the majority of AF patients, although this is still far from ideal, especially in a cardiology clinic. It is even more critical in the group of older patients.

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15.

Trametes versicolor growth and laccase induction with by-products of pulp and paper industry
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Rebelo Barreto Xavier, Ana Maria

; Mora Tavares, Ana Paula

; Ferreira, Rita

; Amado, Francisco

Electronic Journal of Biotechnology

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Jul 2007, Volumen 10 Nº 3 Paginas 444 - 451

Resumen: En | Texto: En | PDF: En

The cultivation of Trametes versicolor for laccase production and cell growth were strongly dependent on experimental conditions namely physical and chemical parameters as well as nutrient availability and inducer stimulation. Biomass growth was compared for a rich medium and for a defined medium in two different temperatures. The best temperature was 28ºC and the maximum specific growth rates were µmax = 0.083 h-1 for the rich medium and µmax = 0.043 h-1 for the defined medium. It was clearly shown that laccase production is not associated with cell growth, indicating that this ligninolytic enzyme must be produced in the defined medium by a secondary metabolism. In order to obtain laccase induction, addition of solid lignin, lignosulphonates, veratryl alcohol, xylidine and ethanol was tested at different concentrations. To optimise laccase activity, the combined effect of inducer addition and simultaneously glucose suppression was studied. The best result for laccase induction (1240 U/L) was obtained with solid lignin, a by-product of pulp and paper industry and the higher laccase activity attained (1583 U/L) was obtained with the combined effect of xylidine addition and glucose suppression.

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