BACKGROUND: Dyslexia is a learning disability that affects children of school-going age and exists in all cultures and backgrounds. Dyslexic children are deficient in phonological awareness, which makes the children to fail to attain the skills of reading, writing and spelling commensurate with their intellectual abilities. Inadequate knowledge about the nature of dyslexia by primary school teachers results in poor categorisation of at-risk children. AIM: This study sought to achieve two objectives. The first was to develop and validate the Teachers Awareness Questionnaire (TAQ), while the second goal was to use the validated TAQ to assess primary school teachers' level of awareness about dyslexia SETTING: Primary school teachers in Nsukka and nearby rural communities filled the TAQ and the Scale of Knowledge and belief about Developmental Dyslexia. Nsukka is called the university town and it is a slow-paced environment that is devoid of the usual hustle and bustle of most major towns in Nigeria. METHODS: The cross-sectional design was employed to gather data for the measurement process. Data were analysed using bivariate correlations and descriptive statistics. RESULTS: The TAQ has good internal consistency (r = 0.77) and an adequate convergent validity (r = 0.74, p < 0.01). Results also reveal that primary school teachers possessed low level of awareness about dyslexia. CONCLUSION: The study findings show that primary school teachers in Nigeria lack the requisite knowledge about dyslexia. The study suggests psycho-education for primary school teachers to empower them with information about the condition CONTRIBUTION: This study measured primary school teachers' level of awareness about dyslexia. The results showed that primary school teachers' awareness about dyslexia is poor, and this suggests that the use of labels (e.g., dullard) by some primary school teachers to describe their pupils may be incorrect. The study recommend to School Management Boards to take action to improve the teachers level of awareness about dyslexia, which would promote early identification of dyslexic pupils and possible intervention.

Abstract Objective To verify the association between victims of bullying and weapon possession among school adolescents. Methods This cross-sectional study was carried out with 2,296 high school students aged 14-19 years. An instrument containing questions from the validated Youth Risk Behavior Survey questionnaire and the National School Health Survey was used. To describe the profile of interviewees, absolute and relative frequencies were calculated, and the chi-square test was applied to verify the existence of associations. To test the association of bullying with weapon possession, Poisson logistic regression (univariate and multivariate) was used. The significance level used for all analyses was 5%. Results Among adolescents interviewed, 23.1% reported being victims of bullying. Among victims of bullying, 37.6% (PR = 1.68; 95% CI = 1.30 - 2.17) reported having already carried some type of weapon (knife, revolver, or truncheon) in the last 30 days, while the reported firearm possession was 38% (PR = 1.67; 95% CI = 1.16 - 2.40) and 47.5% of these adolescents carried some type of weapon (knife, revolver or truncheon) in the school environment (PR = 2.10; 95% CI = 1.50 - 2.93). Conclusions It could be observed that adolescents who are victims of bullying are twice as likely of carrying some type of weapon (knife, revolver, or truncheon) to the school environment, and are also more likely of carrying a firearm.

Abstract The objectives of this study were the biostratigraphic and paleobiogeographic interpretations of the calcareous nannofossil records of the Romualdo Formation (Aptian-Albian) in the south-central portion of the Araripe Basin. The methods used to process the samples were decanting, smear slide, centrifugation, and ultra-thin section confection. The taxonomic and biostratigraphic interpretations were carried out through qualitative and quantitative investigations. A total of 11 genera and 17 species of calcareous nannofossils, namely, Biscutum constans, Biscutum sp., Braarudosphaera africana, Braarudosphaera sp., Calculites sp., Discorhabdus ignotus, Hayesites albiensis, Hayesites sp., Nannoconus bucheri, Nannoconus sp., Retecapsa surirella, Rhagodiscus sp., Thoracosphaera sp., Watznaueria barnesiae, Watznaueria sp., Zeughrabdotus erectus, and Zeughrabdotus noeliae were identified. The integrated analysis of three outcrops suggests two distinct marine phases: the first in the Aptian, recognized in two outcrops, and during the Albian age. The genera Hayesites and Nannoconus suggest a strong Tethyan affinity. Differently, other calcareous nannofossils such as Watznaueria, Thoracosphaera, and Braarudosphaera recorded here are considered more resistant, cosmopolitan, and/or opportunistic species. Biscutum and Zeughrabdotus are sensitive calcareous nannofossils because they are more susceptible to dissolution and cannot be surely used to define this paleobiogeography and biostratigraphic range.

Resumen El presente trabajo forma parte del programa de estudios actualísticos que estamos desarrollando en el marco de nuestras investigaciones arqueológicas en el NE del Macizo del Deseado (Santa Cruz, Argentina). Tiene por objetivo identificar los distintos agentes y procesos tafonómicos que actúan modificando los restos óseos depositados en las distintas unidades geomorfológicas del Parque Nacional Bosques Petrificados de Jaramillo (PNBPJ), para evaluar cuáles de estos microambientes ofrecen condiciones extremas de preservación (buenas vs. malas). Para alcanzar el objetivo llevamos adelante el relevamiento sistemático por transectas de restos de vertebrados modernos distribuidos en distintas unidades geomorfológicas, previamente definidas. Las tendencias obtenidas se discuten con aquellas generadas a partir de la misma metodología en los sectores de Los Toldos, La Huella y Laguna Sierras Blancas, ubicados al noroccidente del PNBPJ. Los resultados indican que en el PNBPJ las mesetas altas son la unidad geomorfológica donde hay menos preservación del registro óseo y que las mesetas intermedias corresponden a las unidades donde existen más posibilidades de localización de contextos en estratigrafía a cielo abierto. Las observaciones realizadas, coinciden con las realizadas previamente en el sector norte del macizo acerca del potencial destructivo de las mesetas altas, y aportan al conocimiento de los procesos de preservación y destrucción del registro óseo que operan en los distintos microambientes del sector. Los resultados obtenidos son de utilidad para el avance de las investigaciones arqueológicas en el área de estudio.

Abstract This work is part of the actualistic study program that we are developing within the framework of our archaeological research in the NW of the Deseado Massif (Santa Cruz, Argentina). Its objective is to identify the different agents and taphonomic processes that act modifying the bone remains deposited in the different geomorphological units of the Jaramillo Petrified Forests National Park (PNBPJ), to evaluate which of these microenvironments offer extreme preservation conditions (good vs. bad). To achieve the objective, we carry out the systematic survey by transects and register the remains of modern vertebrates distributed in different geomorphological units, previously defined. The trends obtained are discussed with those generated from the same methodology in the Los Toldos, La Huella and Laguna Sierras Blancas sectors, located to the northwest of the PNBPJ. The results indicate that in the PNBPJ the high plateaus are the geomorphological unit where there is less preservation of the bone record, and that the intermediate plateaus correspond to the units where there are more possibilities of locating contexts in open-pit stratigraphy. The observations made coincide with those previously made in the northern sector of the massif about the destructive potential of the high plateaus and contribute to the knowledge of the processes of preservation and destruction of the bone record that operate in the different microenvironments of the sector. The results obtained are useful for the advancement of archaeological research in the study area.

Abstract We consider two semi-infinite magnetoelectric media with constant dielectric permittivity separated by a planar interface, whose electromagnetic response is described by non-dynamical axion electrodynamics and investigate the radiation of a point-like electric dipole located perpendicularly to the interface. We start from the exact Green’s function for the electromagnetic potential, whose far-field approximation is obtained using a modified steepest descent approximation. We compute the angular distribution of the radiation and the total radiated power finding different interference patterns, depending on the relative position dipole-observer, and polarization mixing effects which are all absent in the standard dipole radiation. They are a manifestation of the magnetoelectric effect induced by axion electrodynamics. We illustrate our findings with some numerical estimations employing realistic media as well as some hypothetical choices in order to illuminate the effects of the magnetoelectric coupling which is usually very small.

ABSTRACT Mortality due to SARS-CoV-2 is high compared to that caused by other respiratory viruses. This article aims to define the comorbidities associated with high mortality rates or complications that require ventilatory support in intensive care units. A bibliographic search has been performed with respect to comorbidities and/or alterations in laboratory tests and radiographic exams that have been associated with mortality, especially those described in China.

RESUMEN La infección por COVID-19 presenta una elevada mortalidad respecto a otros virus respiratorios. En este artículo buscamos definir las comorbilidades que están asociadas a la elevada mortalidad o a las complicaciones que requieren mayor soporte ventilatorio en unidades de cuidados intensivos. Se ha diseñado una búsqueda bibliográfica con respecto a las comorbilidades y/o alteraciones en los exámenes de laboratorio y los estudios radiológicos que se han asociado a la presencia de mortalidad, especialmente en los casos descritos en China.

Resumo O presente trabalho procura investigar as formas como um território é inventado sob a figuração de um país. Nesse sentido, são explorados os procedimentos que Sarmiento implanta em sua invenção do Delta do Paraná argentino e os desvios propostos pela poética de J. L Ortiz e Madariaga em relação às histórias fundadoras do séc. XIX. Para realizá-lo, são convocadas as propostas teóricas de Derrida, Virno e F. Rodríguez.

Abstract This work seeks to investigate the ways in which a territory is invented under the figuration of a country. In this sense, we explore the procedures that Sarmiento deploys in his invention of the Argentine Paraná Delta and the deviations proposed by the poetics of J. L Ortiz and Madariaga with respect to the founding stories of the s. XIX. In order to carry it out, the theoretical proposals of Derrida, Virno and F. Rodríguez are summoned.

Resumen El presente trabajo busca indagar en los modos como se inventa un territorio bajo la figuración de un país. En este sentido, se exploran los procedimientos que despliega Sarmiento en su invención del Delta del Paraná argentino y se constatan los desvíos que proponen las poéticas de J. L Ortiz y Madariaga respecto de los relatos de fundación del s. XIX. Para realizarlo se convocan, principalmente, las propuestas teóricas de Derrida, Virno y F. Rodríguez.

RESUMO Objetivou-se neste trabalho avaliar o desempenho de cultivares de cebola em função do espaçamento entre plantas. O delineamento experimental utilizado foi em blocos casualizados completos em esquema fatorial 3 x 4 com quatro repetições. Os tratamentos foram constituídos da combinação de três cultivares de cebola (Vale Ouro IPA 11, Serena e Rio das Antas) e quatro espaçamentos entre plantas (3, 6, 8 e 10 cm). As características avaliadas foram: produtividades total, comercial e não comercial de bulbos, porcentagens de bulbos das classes 1, 2, 3 e 4, massa média de bulbos, massa seca de bulbos. Nos cultivos de cebola de forma adensados, as cultivares Rio das Antas e Serena são as mais indicadas, com as maiores produtividades comerciais, respectivamente nos espaçamentos de 6 e 3 cm entre plantas. A cultivar Vale Ouro IPA 11 apresentou maior produtividade comercial no espaçamento de 5 cm entre plantas.

ABSTRACT The objective of this study was to evaluate the performance of onion cultivars as a function of the spacing between plants. The experimental design was a complete randomized block in a 3 x 4 factorial scheme, with four replicates. The treatments were composed of the combination between three onion cultivars (Vale Ouro IPA 11, Serena and Rio das Antas) and four plant spacings (3, 6, 8 and 10 cm). The evaluated characteristics were total, marketable and unmarketable yield of bulbs, percentages of bulbs in classes 1, 2, 3 and 4, bulb mean weight, bulb dry weight. In onion cultivation, the cultivars Rio das Antas and Serena are the most indicated, with the highest marketable yields at 6 and 3 cm spacings between plants, respectively. The cultivar Vale Ouro IPA 11 presented higher marketable yield for the spacing of 5 cm between plants.

RESUMO A cada dia, cepas bacterianas estão tornando-se resistentes a diversos antibióticos, o que faz necessária a busca de novas substâncias eficazes para o tratamento de doenças. Desta forma, este trabalho reporta o estudo preliminar toxicológico, antibacteriano e fitoquímico do extrato etanólico das folhas de Jatropha mollissima (pinhão-bravo, Euphorbiaceae), coletada no Município de Tauá, Ceará, Nordeste Brasileiro. Inicialmente, realizou-se o teste de toxicidade do extrato contra Artemia salina. Na sequencia, foi realizado o ensaio antibacteriano contra quatro cepas bacterianas Gram-negativas (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Hafnia alvei ATCC 51873, Klebsiella pneumoniae ATCC 13883) e uma cepa Gram-positiva (Enterococcus faecalis ATCC 29212). Finalmente, fez-se a análise fitoquímica preliminar do extrato ativo para detecção das principais classes de metabólitos especiais. Como resultado, o extrato etanólico das folhas de J. mollissima se mostrou tóxico para Artemia salina, pois apresentou CL50 igual a 406,02 μg/mL. Quanto à ação antibacteriana, o extrato se mostrou ativo contra a bactéria Gram-positiva Enterococcus faecalis ATCC 29212, apresentando moderada atividade antibacteriana (halo de inibição igual a 7,03 mm). Evidenciou-se no extrato bioativo a presença de cumarinas, fenóis, taninos, flavonoides (flavonóis e flavanonas), alcaloides e esteroides, ambas as classes reportadas como antimicrobianos. Portanto, esse extrato tem potencial para ser usado na produção de fármacos contra infecções causadas por bactérias Gram-positivas. No entanto, as informações direcionam estudos futuros para o isolamento e identificação dos compostos bioativos, monitorados sob a ação antibacteriana mais expressiva.

ABSTRACT Each day, bacterial strains are becoming more resistant to various antibiotics, which requires the search for new effective substances for the treatment of diseases. Thus, this study reports the toxicological, antibacterial, and phytochemical preliminary study of the ethanolic extracts of Jatropha mollissima (pinhão-bravo, Euphorbiaceae) leaves, collected in Tauá, Ceará, Northeast of Brazil. Initially, we performed the toxicity testing of the extract against Artemia salina. Then, we conducted the antibacterial assay against four Gram-negative bacterial strains (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Hafnia alvei ATCC 51873, Klebsiella pneumoniae ATCC 13883), and one Gram-positive strain (Enterococcus faecalis ATCC 29212). Finally, we carried out the preliminary phytochemical analysis of the active extract to detect the main classes of special metabolites. As a result, the ethanolic extract of J. mollissima leaves was toxic to Artemia salina, because it presented LC50 equal to 406.02 µg/mL. Regarding antibacterial action, the extract was active against the Gram-positive bacteria Enterococcus faecalis ATCC 29212, with moderate antibacterial activity (inhibition zone equal to 7.03 mm). The bioactive extract had the presence of coumarins, phenols, tannins, flavonoids (flavanols and flavonones), alkaloids and steroids, both classes reported as antimicrobials. Therefore, this extract has the potential to be used in the production of drugs against infections caused by Gram-positive bacteria. However, these information require further studies for the isolation and identification of bioactive compounds, monitored under the more expressive antibacterial action.

Objectives: To assess the incidence and clinical parameters that could influence migration of seeds in localized prostate cancer patients treated by stranded versus loose sources by Iodine-125 brachytherapy. Material and Methods: 100 patients were treated from January/1998 until December/2006. Age, PSA, clinical stage, Gleason, prostate volume, number of seeds, activity of radioactive seeds, and dosimetric parameters, such as V100, V150 and D90 were evaluated. Results: Mean follow-up was 79 months (18 - 120. CI 95%: 72 - 85). Overall, 6 of 100 patients experienced seed migration. Seed migration was found in 4/50 (8%) patients using loose seeds and in 2/50 (4%) treated by stranded seeds. Mean value dosimetric parameters for stranded seeds were greater than those for loose seeds (V100(%): 88.7/82, D90(Gy): 149.2/140.3, D90(%): 104.2/93.8, V150 (%): 53.8/47, respectively). No significant difference in migration of seeds was detected between loose and stranded seeds considering age (p = 0.33), PSA (p = 0.391), prostate volume (p = 0.397), activity of radioactive seeds (p = 0.109), number of seeds (p = 0.338), V100 (p = 0.332), although significant differences were measured in the values of D90(% and Gy) (p = 0.022 and 0.011) and V150 (p = 0.023). Conclusions: Seed migration after brachytherapy might occur and it does affect post-implant dosimetry.

OBJECTIVES: To estimate Chlamydia trachomatis (CT) infection prevalence and associated risk factors among a low-income marginalized urban population in Peru. METHODS: Between April 2003 and April 2005, men and women at high-risk for sexually transmitted infections (STIs) were recruited from low-income urban areas in three coastal cities in Peru (Chiclayo, Lima, and Trujillo). Consenting participants were studied using a sero-epidemiologic survey. Urine and vaginal swabs collected from men and women were evaluated using polymerase chain reaction (PCR) (COBAS® AMPLICOR (CT/NG) Test, Roche Molecular Diagnostics, Branchburg, NJ, USA) for CT. RESULTS: Among the 2 440 participants recruited for the study (2 145 men and 295 women), overall prevalence of CT infection was 6.6% (95% CI, 5.6-7.6%): 5.5% (95% CI, 4.5-6.5%) in men and 14.9% (95% CI, 11.7-27.1%) in women. Chlamydial infection was inversely associated with age and positively associated with HIV infection and dysuria in men. Among women, chlamydial infection was inversely associated with age and positively associated with number of sex partners. CONCLUSIONS: CT infection was common among high-risk men and women in urban coastal Peru. Because chlamydial infection is associated with complications related to female reproduction, including infertility and ectopic pregnancy, interventions to prevent and treat infection and studies to determine the feasibility of population-based screening for CT should be conducted among the high-risk female population.

OBJETIVOS: Estimar la prevalencia de la infección por Chlamydia trachomatis y los factores de riesgo asociados en una población marginal urbana de bajos ingresos de Perú. MÉTODOS: Entre abril de 2003 y abril de 2005 se captaron hombres y mujeres con alto riesgo de contraer infecciones de transmisión sexual, en áreas urbanas de bajos ingresos de tres ciudades costeras de Perú (Chiclayo, Lima y Trujillo). Los participantes que aceptaron colaborar respondieron una encuesta seroepidemiológica y se analizaron muestras de orina de los hombres y exudados vaginales de las mujeres mediante la reacción en cadena de la polimerasa con el sistema para C. trachomatis COBAS® AMPLICOR (Roche Molecular Diagnostics, NJ, EE.UU.) RESULTADOS: En el estudio participaron 2 440 personas (2 145 hombres y 295 mujeres). La prevalencia general de infección por C. trachomatis fue de 6,6% (intervalo de confianza de 95% [IC95%]: 5,6 a 7,6%): 5,5% (IC95%: 4,5 a 6,5%) en hombres y 14,9% (IC95%: 11,7 a 27,1%) en mujeres. La infección por clamidia se asoció inversamente con la edad y directamente con la infección por VIH y la disuria en los hombres. En las mujeres, esta infección se asoció inversamente con la edad y directamente con el número de parejas sexuales. CONCLUSIONES: La infección por C. trachomatis fue frecuente en los hombres y mujeres con alto riesgo en las zonas urbanas costeras de Perú. Como esta infección está asociada con complicaciones que afectan la salud reproductiva de las mujeres, como infertilidad y embarazos ectópicos, se deben realizar intervenciones para prevenir y tratar la infección por C. trachomatis y se deben emprender estudios para determinar la factibilidad del tamizaje general de esta infección en la población femenina de alto riesgo.

OBJECTIVE: To report the seven-year preliminary results of a single-center on brachytherapy with Iodine-125 seeds, used in combination with external beam radiotherapy in selected patients with localized prostate cancer (T1-T2). MATERIALS AND METHODS: All 105 patients treated by brachytherapy with Iodine-125 seeds, from January/1998 to December/2004, were retrospectively analyzed. The prescribed dose was 144 Gy at the periphery of the prostate for isolated brachytherapy, and 110 Gy for the combination with external beam radiotherapy. The external beam radiotherapy dose was 45 Gy, at the prostatic bed. Neoadjuvant hormone therapy was indicated for selected patients, who received luteinizing hormone-releasing hormone (LH-RH) and/or antiandrogens. For definition of biochemical relapse, it was adopted the American Society for Therapeutic Radiology and Oncology consensus. RESULTS: Of the 105 patients treated, 90 were followed for a mean period of 70 months. Biochemical disease control was achieved in 62 (69%) and biochemical recurrence was manifested in 28 (31%). The analysis of each risk group showed biochemical disease control rates of 79%, 71% and 52% in the low, intermediate and high risk groups, respectively. The mean time for biochemical recurrence was 22 months. Genitourinary acute toxicity was classified as grade 0-2 (RTOG) in 88.5% and in 94.2% for the late toxicity (RTOG/EORTC). Gastrointestinal acute toxicity was graded as 0-2 (RTOG) in 100% and in 97.7% for the late morbidity. No grade 5 was detected. CONCLUSIONS: Brachytherapy with Iodine-125 seeds is an effective alternative treatment for early stage prostatic cancer, with good biochemical disease control rates and low to moderate toxicity. The best results were obtained in low and intermediate risk patients.

Introduction: Periodontitis is a chronic disease that results from an interaction of a mixed bacterial challenge and the host response. Objective: The purposes of this study were to evaluate the IgG serum levels to Porphyromonas gingivalis antigens by ELISA in individuals with different periodontal conditions correlated with clinical parameters, and to analyze the immunoreactivity profiles by Western blotting. Methods: Serum IgG levels against the cell sonicate antigen from P. gingivalis ATCC 33277 of 28 patients with chronic periodontitis (CP), 10 patients with gingivitis (G) and 21 periodontally healthy individuals (H) were measured by ELISA and Western immunoblotting. Results: In the CP group, sera reactivity by ELISA was significantly higher than in the G and H groups (Kruskal-Wallis p<0.001; Dunnet t3 p= 0.001 and Dunnet t3 p= 0.0001). There was no statistically significant difference between G and HP reactivity (Dunnett t3 p=0.617). Among individuals with chronic periodontitis, the IgG-anti-P. gingivalis serum levels were positively correlated with percentage of clinical attachment level =5mm (r s = + 0.375, p<0.05) and a negative correlation was found between IgG-anti-P. gingivalis levels and percentage of probing pocket depth 0-3mm (r s = - 0. 411, p< 0.05). The analysis of sera immunoreactivity profiles to sonicate antigen by Western blotting showed differences between the sera of CP, G and H group individuals. The serum from CP frequently reacted with high molecular weight (103 kDa, 86 kDa, 72 kDa, 60 kDa, 58 kDa, 52 kDa) protein fractions. Conclusions: Serum levels of IgG anti-P. gingivalis distinguished individuals with chronic periodontitis, gingivitis and healthy periodontium. There was a correlation between clinical parameters and serum IgG levels against P. gingivalis. There was a difference in the recognition profile of protein fractions among the studied groups and some bands were more specific