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The aesthetics of Gannan Hakka architecture in modern housing: A design psychology perspective
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Lei, Xiang

; Cao, Hao

; Guo, Limin

HTS Theological Studies

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2023, Volumen 79 Nº 4 Paginas 1 - 7

Resumen: En | Texto: En | PDF: En

The rapid acceleration of societal change has subjected contemporary individuals to prolonged periods of diverse pressures, leading to substantial psychological strain, resulting in anxiety, depression, and compromised mental well-being. Within this context, the home has evolved into a vital refuge for modern individuals, offering both physical and psychological respite. Through experimental intervention, this study examines two distinct residential groups: those adhering to traditional housing and those residing in characteristic folk houses, specifically Gannan Hakka architecture. Analysing the psychological state of contemporary individuals and integrating Gannan Hakka architectural elements into folk house design through a psychologically informed approach, this research aims to enhance residents' aesthetic experiences and alleviate psychological distress. The study involved 120 volunteers with varying psychological stress levels, categorised into characteristic and traditional folk house groups. Psychological assessments evaluated stress, self-efficacy, and quality of life. Findings reveal significantly improved psychological well-being, self-efficacy, and quality of life among the characteristic residential group, affirming the benefits of Gannan Hakka architecture integration. This research underscores the importance of addressing modern individuals' environmental needs and proposes the integration of Gannan Hakka cultural elements into residential design to enhance well-being. CONTRIBUTION: This study demonstrates the application of Hakka culture in contemporary housing profoundly influences residents' lives, enabling both relaxation and a deeper cultural connection. This integration facilitates a comprehensive understanding of Hakka culture, promoting its preservation. Notably recognised for hospitality and diligence, Hakka culture enhances individuals' appreciation of tradition, fostering physical and mental rejuvenation. These findings offer valuable insights for practical theology scholars and practitioners exploring the impact of religious aspects on modern residential design from a psychological perspective

https://doi.org/10.4102/hts.v79i4.8850

Saúde Cardiovascular e Fibrilação ou Flutter Atrial: Um Estudo Transversal do ELSA-Brasil
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Santos, Itamar S.

; Lotufo, Paulo A.

; Goulart, Alessandra C.

; Brant, Luisa C. C.

; Pinto Filho, Marcelo M

; Pereira, Alexandre C.

; Barreto, Sandhi M.

; Ribeiro, Antonio L. P.

; Thomas, G Neil

; Lip, Gregory Y. H.

; Bensenor, Isabela M.

; Arasalingam, Ajini

; Beane, Abi

; Bensenor, Isabela M

; Brocklehurst, Peter

; Cheng, Kar Keung

; El-Bouri, Wahbi

; Feng, Mei

; Goulart, Alessandra C

; Greenfield, Sheila

; Guo, Yutao

; Guruparan, Mahesan

; Gusso, Gustavo

; Gooden, Tiffany E

; Haniffa, Rashan

; Humphreys, Lindsey

; Jolly, Kate

; Jowett, Sue

; Kumarendran, Balachandran

; Lancashire, Emma

; Lane, Deirdre A

; Li, Xuewen

; Lip (Co-PI), Gregory Y.H.

; Li, Yan-guang

; Lobban, Trudie

; Lotufo, Paulo A

; Manseki-Holland, Semira

; Moore, David J

; Nirantharakumar, Krishnarajah

; Olmos, Rodrigo D

; Paschoal, Elisabete

; Pirasanth, Paskaran

; Powsiga, Uruthirakumar

; Romagnolli, Carla

; Santos, Itamar S

; Shantsila, Alena

; Sheron, Vethanayagam Antony

; Shribavan, Kanesamoorthy

; Szmigin, Isabelle

; Subaschandren, Kumaran

; Surenthirakumaran, Rajendra

; Tai, Meihui

; Neil Thomas (Co-PI), G

; Varella, Ana C

; Wang, Hao

; Wang, Jingya

; Zhang, Hui

; Zhong, Jiaoyue

Arquivos Brasileiros de Cardiologia

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2022, Nº ahead

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A associação entre o status de saúde cardiovascular ideal ( ideal cardiovascular health ( ICVH) e diagnóstico de fibrilação ou flutter atrial (FFA) foi menos estudado em comparação a outras doenças cardiovasculares. Objetivos Analisar a associação entre o diagnóstico de FFA e métricas e escores de ICVH no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Métodos Este estudo analisou dados de 13141 participantes com dados completos. Os traçados eletrocardiográficos foram codificados de acordo com o Sistema de Minnesota, em um centro de leitura centralizado. As métricas do ICVH (dieta, atividade física, índice de massa corporal, tabagismo, glicemia de jeju, e colesterol total) e escores do ICVH foram calculados conforme proposto pela American Heart Association . Modelos de regressão logística bruta e ajustada foram construídos para analisar associações de métricas e escores do ICVH com diagnóstico de FFA. O nível de significância foi estabelecido em 0,05. Resultados A idade mediana da amostra foi de 55 anos, e 54,4% eram mulheres. Nos modelos ajustados, os escores de ICVH não apresentaram associação significativa com diagnóstico de FFA prevalente [odds ratio (OR):0,96; intervalo de confiança de 95% (IC95%):0,80-1,16; p=0,70). Perfis de pressão arterial ideal (OR:0,33; IC95%:0,1-0,74; p=0,007) e colesterol total ideal (OR:1,88; IC95%:1,19-2,98; p=0,007) foram significativamente associados com o diagnóstico de FFA. Conclusões Não foram identificadas associações significativas entre escores de ICVH global e diagnóstico de FFA após ajuste multivariado em nossas análises, devido, ao menos em parte, às associações antagônicas da FFA com métricas de pressão arterial e de colesterol total do ICVH. Nossos resultados sugerem que estimar a prevenção da FFA por meio de escore de ICVH global pode não ser adequado, e as métricas do ICVH devem ser consideradas separadamente.

Abstract Background The association between ideal cardiovascular health (ICVH) status and atrial fibrillation or flutter (AFF) diagnosis has been less studied compared to other cardiovascular diseases. Objective To analyze the association between AFF diagnosis and ICVH metrics and scores in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods This study analyzed data from 13,141 participants with complete data. Electrocardiographic tracings were coded according to the Minnesota Coding System, in a centralized reading center. ICVH metrics (diet, physical activity, body mass index, smoking, blood pressure, fasting plasma glucose, and total cholesterol) and scores were calculated as proposed by the American Heart Association. Crude and adjusted binary logistic regression models were built to analyze the association of ICVH metrics and scores with AFF diagnosis. Significance level was set at 0.05. Results The sample had a median age of 55 years and 54.4% were women. In adjusted models, ICVH scores were not significantly associated with prevalent AFF diagnosis (odds ratio [OR]:0.96; 95% confidence interval [95% CI]:0.80-1.16; p=0.70). Ideal blood pressure (OR:0.33; 95% CI:0.15–0.74; p=0.007) and total cholesterol (OR:1.88; 95% CI:1.19–2.98; p=0.007) profiles were significantly associated with AFF diagnosis. Conclusions No significant associations were identified between global ICVH scores and AFF diagnosis after multivariable adjustment in our analyses, at least partially due to the antagonistic associations of AFF with blood pressure and total cholesterol ICVH metrics. Our results suggest that estimating the prevention of AFF burden using global ICVH scores may not be adequate, and ICVH metrics should be considered in separate.

https://doi.org/10.36660/abc.20210970

Effect of Calcium Dobesilate in Preventing Contrast-Induced Nephropathy in Patients with Diabetes and Chronic Kidney Disease
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Zhang, Hao

; Guo, Shao-Hua

; Xue, Zheng-Kai

; Zhang, Ya-Ru

; Wang, Jia-Rui

; Che, Jing-Jin

; Liu, Tong

; Tao, Hua-Yue

; Li, Guang-Ping

; Rha, Seung-Woon

; Ashraful-Haque, Swapnil-Zaman

; Chen, Kang-Yin

Clinics

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2021, Volumen 76 elocation e2942

Resumen: En | Texto: En | PDF: En

OBJECTIVES: This study assessed the protective effect of calcium dobesilate against contrast-induced nephropathy (CIN) after coronary angiography (CAG) or percutaneous coronary intervention (PCI) in patients with diabetes and chronic kidney disease (CKD). METHODS: A total of 130 patients with diabetes and CKD estimated glomerular filtration rate: 30-90 mL/min/1.73m2 were enrolled and included in the analysis. They were divided into experimental (n=65) and control groups (n=65). Patients in the experimental group were administered oral calcium dobesilate (500 mg) three times daily for 2 days before and 3 days after the procedure. The serum creatinine (SCr), cystatin C (Cys C), and neutrophil gelatinase-associated lipocalin (NGAL) levels were measured before and after the procedure. RESULTS: The mean SCr level at 24h after the procedure was found to be significantly lower in the experimental group than in the control group (79.1±19.6 μmol/L vs. 87.0±19.3 μmol/L, p=0.023). However, the Cys C and NGAL levels were not significantly different between the two groups at all measurement time points (all p>0.05). The incidence of CIN defined by the SCr level was significantly lower in the experimental group than in the control group (3 [4.6%] vs. 13 [20.0%], p=0.017). However, the incidence of CIN defined by the Cys C level was not statistically different between the two groups (7 [10.8%] vs. 7 [10.8%], p=1.000). CONCLUSIONS: This study revealed that calcium dobesilate has no preventive effect against CIN in patients with diabetes and CKD.

https://doi.org/10.6061/clinics/2021/e2942 77 descargas

Effects of propofol pretreatment on myocardial cell apoptosis and SERCA2 expression in rats with hepatic ischemia/reperfusion
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Yu, Shuzhen

; Guo, Yongqing

; Zhang, Weiwei

; Zheng, Lina

; Ren, Junming

; Jin, Jianmin

; Yu, Baofeng

; Zhang, Yu

; Wang, Hao

; Zhang, Yuhong

Revista Brasileira de Anestesiologia

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Nov 2018, Volumen 68 Nº 6 Paginas 591 - 596

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A lesão hepática por isquemia-reperfusão é um processo fisiopatológico comum em cirurgias hepáticas. Mais estudos ainda são necessários para avaliar se o propofol pode reduzir a lesão de isquemia-reperfusão miocárdica induzida pela lesão de isquemia-reperfusão hepática em ratos, juntamente com os mecanismos que estão relacionados. Objetivo: Investigar se propofol protege as células do miocárdio da apoptose com a lesão hepática por isquemia-reperfusão. Métodos: Ratos machos da raça Sprague-Dawley (n = 18) foram alocados aleatoriamente em três grupos: Grupo Sham (Grupo S, n = 6), Grupo Lesão Hepática por Isquemia-reperfusão (Grupo IR, n = 6) e Grupo Propofol (Grupo P, n = 6). O Grupo S foi submetido apenas à laparotomia. O grupo IR foi submetido à isquemia por 30 min e reperfusão por 4 h. O grupo P foi submetido à mesma isquemia do grupo IR, com a administração de 120 mg.kg-1 de propofol iniciada 10min antes da isquemia, seguida de infusão contínua a 20 mg.kg-1.h-1. A apoptose celular foi examinada por meio do ensaio de marcação de terminações dUTP pela deoxinucleotidil transferase. Retículo endoplasmático Ca2+-ATPase2 (SERCA2) e caspase-3 do ácido aspártico contendo cisteína (caspase-3 clivada) foram avaliados com o ensaio western blot e reação em cadeia da polimerase. Resultados: A taxa de apoptose foi maior com mRNA e proteína de SERCA2 regulados para baixo e caspase-3 clivada suprarregulada no Grupo IR, em comparação com o Grupo S (p < 0,01). A taxa de apoptose foi menor com mRNA e proteína de SERCA2 suprarregulada e caspase-3 clivada sub-regulada no Grupo P, em comparação com o Grupo IR (p < 0,01). Conclusões: O propofol pode reduzir a apoptose de células miocárdicas induzida por lesão hepática por isquemia-reperfusão. Entretanto, pode suprarregular o mRNA e a proteína de SERCA2 em ratos.

Abstract Introduction: Hepatic ischemia-reperfusion injury is a common pathophysiological process in liver surgery. Whether Propofol can reduce myocardial ischemia-reperfusion injury induced by hepatic ischemia-reperfusion injury in rats, together with related mechanisms, still needs further studies. Objective: To investigate if propofol would protect the myocardial cells from apoptosis with hepatic ischemia-reperfusion injury. Methods: Male Sprague-Dawley rats (n = 18) were randomly allocated into three groups: Sham Group (Group S, n = 6), Hepatic Ischemia-reperfusion Injury Group (Group IR, n = 6) and Propofol Group (Group P, n = 6). Group S was only subjected to laparotomy. Group IR was attained by ischemia for 30 min and reperfusion for 4 h. Group P was subjected identical insult as in Group IR with the administration of propofol started 10 min before ischemia with 120 mg.kg−1, following by continuous infusion at 20 mg.kg−1.h−1. Cell apoptosis was examined by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay. Endoplasmic reticulum Ca2+-ATPase2 (SERCA2) and cysteine-containing aspartic acid cleaved-caspase3 (cleaved-caspase3) were assayed by western blot and Altimeter polymerase chain reaction. Results: Apoptosis rate was increased, with mRNA and protein of SERCA2 down-regulated and cleaved-caspase3 up-regulated in Group IR compared with Group S (p < 0.01). Apoptosis rate was decreased, with mRNA and protein of SERCA2 up-regulated and cleaved-caspase3 down-regulated in Group P compared with Group IR (p < 0.01). Conclusions: Propofol can reduce hepatic ischemia-reperfusion injury-induced myocardial cell apoptosis, meanwhile, can up-regulate mRNA and protein of SERCA2 in rats.

https://doi.org/10.1016/j.bjane.2018.07.001 642 descargas

Development of a novel compound microbial agent for degradation of kitchen waste
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Zhao, Kaining

; Xu, Rui

; Zhang, Ying

; Tang, Hao

; Zhou, Chuanbin

; Cao, Aixin

; Zhao, Guozhu

; Guo, Hui

Brazilian Journal of Microbiology

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Jul 2017, Volumen 48 Nº 3 Paginas 442 - 450

Resumen: En | Texto: En | PDF: En

Abstract Large quantities of kitchen waste are produced in modern society and its disposal poses serious environmental and social problems. The aim of this study was to isolate degradative strains from kitchen waste and to develop a novel and effective microbial agent. One hundred and four strains were isolated from kitchen waste and the 84 dominant strains were used to inoculate protein-, starch-, fat- and cellulose-containing media for detecting their degradability. Twelve dominant strains of various species with high degradability (eight bacteria, one actinomycetes and three fungi) were selected to develop a compound microbial agent "YH" and five strains of these species including H7 (Brevibacterium epidermidis), A3 (Paenibacillus polymyxa), E3 (Aspergillus japonicus), F9 (Aspergillus versicolor) and A5 (Penicillium digitatum), were new for kitchen waste degradation. YH was compared with three commercial microbial agents-"Tiangeng" (TG), "Yilezai" (YLZ) and Effective Microorganisms (EM), by their effects on reduction, maturity and deodorization. The results showed that YH exerted the greatest efficacy on mass loss which decreased about 65.87% after 14 days. The agent inhibited NH3 and H2S emissions significantly during composting process. The concentration of NH3 decreased from 7.1 to 3.2 ppm and that of H2S reduced from 0.7 to 0.2 ppm. Moreover, E4/E6 (Extinction value460nm/Extinction value665nm) of YH decreased from 2.51 to 1.31, which meant YH had an obvious maturity effect. These results highlighted the potential application of YH in composting kitchen waste.

https://doi.org/10.1016/j.bjm.2016.12.011 2541 descargas

Preparation of a Nitrite Electrochemical Sensor Based on Polyaniline/ Graphene‑Ferrocenecarboxylic Acid Composite Film Modified Glass Carbon Electrode and its Analytical Application
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Wei, Yuli

; Fang, Fang

; Yang, Wu

; Guo, Hao

; Niu, Xiuli

; Sun, Lijun

Journal of the Brazilian Chemical Society

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Oct 2015, Volumen 26 Nº 10 Paginas 2003 - 2013

Resumen: En | Texto: En | PDF: En

A sensitive and stable electrochemical sensor based on polyaniline/graphene-ferrocenecarboxylic acid (PANI/GR-FCA) composite film modified glass carbon electrode for determination of nitrite was presented and its morphology and structure were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), Fourier transform infrared spectroscopy (FTIR) and X-ray powder diffraction (XRD). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques were used to investigate the electrochemical behavior of the nitrite oxidation, which exhibited an enhanced voltammetric response at the modified electrode. In the optimal condition, the oxidation of nitrite in Britton-Robinson buffer solution (BR) of pH 4.0 had the higher peak current than the bare electrode. A linear calibration curve over the concentration range 0.4-300 µmol L-1 of nitrite were obtained with a linear regression equation I (µA) = 0.1589 + 0.0020C (µmol L-1) (R = 0.9991, n = 13) and the detection limit was down to 0.02 mmol L-1 (S/N = 3). The recoveries of all determinations ranged between 96-102%. At the same time, the modified electrode showed a good long-term stability and reproducibility for determination of nitrite, as well as high selectivity.

https://doi.org/10.5935/0103-5053.20150180 4910 descargas

Proteomics analysis after traumatic brain injury in rats: the search for potential biomarkers
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Ding, Jun

; Ding, Zhengang

; Yuan, Fang

; Guo, Jianyi

; Chen, Hao

; Gao, Wenwei

; Wang, Ren

; Gu, Yi

; Chen, Jiong

; Guo, Yan

; Tian, Hengli

Arquivos de Neuro-Psiquiatria

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Abr 2015, Volumen 73 Nº 4 Paginas 342 - 349

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Muitos estudos de expressão proteica após lesão cerebral traumática (LCT) identificam biomarcadores para determinação diagnóstica ou prognóstica do LCT. No presente estudo, foram investigados marcadores proteicos adicionais de LCT, através de um aparelho de impacto no fluxo e perfusão em ratos S-D. Eletroforese bidimensional em gel e espectrometria de massa foram utilizadas para identificar diferentes proteínas expressas. Após a análise proteômica, detectamos marcas de proteínas 405 e 371, com pH variando entre 3-10 no córtex de ratos sham e naqueles com contusão cerebral, respectivamente. Oitenta marcas proteicas foram expressas nos dois grupos e 20 destas proteínas foram identificadas. Este estudo validou o estabelecimento de biomarcadores de LCT e identificou potencial biomarcadores que poderão ser estudados em estudos futuros.

Many studies of protein expression after traumatic brain injury (TBI) have identified biomarkers for diagnosing or determining the prognosis of TBI. In this study, we searched for additional protein markers of TBI using a fluid perfusion impact device to model TBI in S-D rats. Two-dimensional gel electrophoresis and mass spectrometry were used to identify differentially expressed proteins. After proteomic analysis, we detected 405 and 371 protein spots within a pH range of 3-10 from sham-treated and contused brain cortex, respectively. Eighty protein spots were differentially expressed in the two groups and 20 of these proteins were identified. This study validated the established biomarkers of TBI and identified potential biomarkers that could be examined in future work.

https://doi.org/10.1590/0004-282X20150006 2892 descargas

Trade structure, trade mode and the urban-rural income gap in China
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Wei, Hao

; Li, Hongbing

; Guo, Ye

South African Journal of Economic and Management Sciences

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2013, Volumen 16 Nº 2 Paginas 96 - 114

Resumen: En | Texto: En | PDF: En

This paper analyses the effect of foreign trade in China on the urban-rural income gap from certain angles including trade scale, trade structure and trade mode at the national and provincial levels. The empirical results indicate that, from the perspective of trade scale, the export and import in the eastern and national regions have an expansion effect on the urban-rural income gap, and, in the central regions, they have a reduction effect. Furthermore, export in the western regions has a reduction effect while import in these regions did not have a significant effect. From the perspective of trade structure, the trade of high-tech products and labour-intensive products in the national and eastern regions has an expansion effect, and the trade of the above-mentioned products in the central regions has a reduction effect. The trade of labour-intensive products in the western regions has a reduction effect, and that of high-tech products an expansion effect. From the perspective of trade mode, processing trade and general trade in the national and eastern regions have an expansion effect, while in the central regions they have a reduction effect. General trade in the western regions would expand the urban-rural income gap, and processing trade does not have a significant effect. Consequently, when the South African Government is working out trade multiplicative and corresponding policy, they should consider the development of foreign trade and should pay attention to the labour market structure.

1377 descargas

Preparation of tunable wettability polymer (ionic liquid) brushes at rough substrate using surface initiated atom transfer radical polymerization
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Sun, Kanjun

; Yang, Wu

; Ma, Guofu

; Wan, Fei

; Gao, Jinzhang

; Lei, Ziqiang

; Guo, Hao

Journal of the Brazilian Chemical Society

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Mar 2011, Volumen 22 Nº 3 Paginas 478 - 483

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Através da técnica de polimerização radicalar por transferência atômica (ATRP) foram preparadas novos polímeros tipo pente com molhabilidade ajustável (líquido iônico) de hexafluorfosfato poli[2-(1-butilimidazolino-3-ila)etila metacrilato (PBIMH-PF6-), a partir de um substrato bruto modificado com uma camada iniciadora composta de brometo 2-bromoisobutirila. Várias técnicas de caracterização como elipsometria, medidas de ângulo de contato estático, espectroscopia fotoeletrônica de raios X (XPS) e microscopia de força atômica (AFM) foram utilizadas para caracterizar os filmes em cada etapa de modificação da superfície. Estudos cinéticos revelaram um aumento linear na espessura do filme polimérico em função do tempo de reação, indicando que o crescimento da cadeia a partir da superfície, é um processo cujo controle apresenta características de polimerização "viva". As medidas de molhabilidade indicaram que as interações de troca iônica podem ser usadas para alterar as características da superfície de hidrofilicidade para hidrofobicidade de forma reversível. O substrato bruto obtido por ataque químico exibiu uma melhor hidrofobicidade quando comparado à superfície lisa do substrato plano modificado com as mesmas cadeias poliméricas tipo pente (líquido iônico).

Using surface initiated atom transfer radical polymerization (ATRP), novel tunable wettability polymer (ionic liquid) brushes poly[2-(1-butylimidazolium-3-yl)ethyl methacrylate hexafluorophosphate] (PBIMH-PF6-) from a rough substrate modified with an initiator layer composed of 2-bromoisobutyryl bromide was prepared. Various characterization techniques including ellipsometry, static water contact angle measurements, X-ray photoelectron spectroscopy (XPS), and atomic force microscope (AFM) were used to characterize the films for each surface modification step. Kinetic studies revealed a linear increase in polymer film thickness with reaction time, indicating that chain growth from the surface was a controlled process with a "living" characteristic. Wetting measurements indicated that ion exchanging interactions can be used to switch surface characteristics from hydrophilicity to hydrophobicity in a reversible manner. Compared with the smooth surface of the flat substrate modified with the same polymer (ionic liquid) brushes, the rough substrate by chemical etching exhibited better hydrophobicity.

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