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Resumo O objetivo foi identificar o arcabouço regulatório e as orientações federais que sustentam o processo de implementação de tecnologias em saúde no Sistema Único de Saúde (SUS), por meio da análise de documentos e legislações relacionados à Política Nacional de Gestão de Tecnologias de Saúde, publicados entre 2009 e 2021. Foi realizada busca e seleção dos documentos e posterior extração de dados, agrupados por três categorias: normativas estruturantes, recomendações na avaliação de tecnologias e recomendações nas diretrizes clínicas. Em 38,8% das normativas, foram identificadas citações à implementação relacionadas principalmente às diretrizes clínicas do SUS, mas nenhum documento dedicado a orientar as ações de implementação. As recomendações relacionadas às implementações foram identificadas em 27,1% dos relatórios e em 66,1% das diretrizes, mas sem padronização e, de modo geral, pouco detalhadas, com foco em recursos e ações necessárias para a disponibilização da tecnologia, ao invés de métodos e intervenções para implementação. Os resultados confirmam a existência de uma lacuna de diretrizes formais para guiar o processo de implementação no Brasil, o que se constitui em oportunidade para o desenvolvimento de modelos alinhados à realidade do SUS.

Abstract This study aimed to identify the regulatory framework and federal guidelines that support the process of implementing health technologies in the Unified Health System (SUS) through analysis of documents and legislation related to the National Health Technology Management Policy, published between 2009 and 2021. The search and selection of documents and subsequent data extraction were carried out. The documents were grouped into three categories: structural regulatory documents, recommendations on evaluation of technologies, and recommendations on clinical guidelines. In 38.8% of the regulatory documents, citations to implementation related mainly to SUS clinical guidelines were identified; however, no document dedicated to guiding implementation actions was identified. Recommendations related to implementations were identified in 27.1% of the reports and 66.1% of the guidelines, although without standardization and, in general, in little detail, focusing on resources and actions needed for making technology available rather than on methods and interventions for its implementation. The results evidence a gap in formal guidelines to guide the implementation process in Brazil, representing an opportunity for the development of models aligned with the reality of the SUS.

https://doi.org/10.1590/1413-81232024291.00322023

Implementação de tecnologias em saúde no Brasil: análise de orientações federais para o sistema público de saúde
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Silva, Sarah Nascimento

; Mello, Nicole Freitas de

; Ribeiro, Laís Raquel

; Silva, Rosiana Estéfane da

; Cota, Gláucia

Ciência & Saúde Coletiva

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2024, Volumen 29 Nº 1 elocation e00322023

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.00322023

Implementação de tecnologias em saúde no Brasil: análise de orientações federais para o sistema público de saúde
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Silva, Sarah Nascimento

; Mello, Nicole Freitas de

; Ribeiro, Laís Raquel

; Silva, Rosiana Estéfane da

; Cota, Gláucia

Ciência & Saúde Coletiva

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2024, Volumen 29 Nº 1 elocation e00322023

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.00322023

Implementação de tecnologias em saúde no Brasil: análise de orientações federais para o sistema público de saúde
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Silva, Sarah Nascimento

; Mello, Nicole Freitas de

; Ribeiro, Laís Raquel

; Silva, Rosiana Estéfane da

; Cota, Gláucia

Ciência & Saúde Coletiva

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2024, Volumen 29 Nº 1 elocation e00322023

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.00322023

Adherencia al tratamiento y nivel de conocimiento en adultos con hipertensión arterial, Asunción 2022
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Recalde Mello, Laura

; Argüello Batista, Veridiana

; Báez Morínigo, Paula Elena

; Benítez Florentín, Clara Dahiana

; Cubelli Alvarenga, María Jesús

; Jara Cabrera, Nadia Monserrath

; Martínez Ocampos, Andrea Raquel

; Miño Rolón, Néstor Gustavo

; Rojas Aguilar, Gladys Mabel

; Sánchez Rotela, Patricia Soledad

; Vallejos García, Natalia Margarita

; Brítez Benítez, Luis Enrique

; Garay Chamorro, Blanca Liliana

; Paniagua Fariña, Ariela Alexandra

Revista Virtual de la Sociedad Paraguaya de Medicina Interna

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Mar 2023, Volumen 10 Nº 1 Paginas 11 - 19

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Adherence to treatment and level of knowledge in patients with arterial hypertension are key factors to control this condition and avoid complications. Objectives: To determine the degree of adherence to treatment, the level of knowledge and comorbidities in patients with arterial hypertension in an urban area of Asunción, Paraguay, in 2022. Methodology: An observational, descriptive, cross-sectional design was applied. Men and women over 18 years of age, known carriers of arterial hypertension, residing in Sajonia neighborhood between May and October 2022, were included. The data were obtained through house-to-house interviews. Demographic variables, the level of adherence with the Morisky Green test and the level of knowledge about the disease with the Batalla test were measured. The research was approved by the Ethics Committee of the Universidad Privada del Este, Paraguay. Results: Four hundred twenty-five subjects participated in the study, predominantly female (61.1%). Diabetes mellitus was referred to by 28.9% of the interviewees. The Morisky Green test detected that 60% of the subjects forget to take their medication, 25% do not take it at the indicated time, 29% take it if they feel well, and 44% stop taking it if they feel undesirable effects. The Batalla test found that 7% believe that arterial hypertension is not for life, 9% believe that the condition is not controlled with diet and medication, and 5.8% could not refer to at least one target organ. Conclusion: Adherence to the treatment of arterial hypertension and the level of knowledge about this condition was not adequate.

RESUMEN Introducción: la adherencia al tratamiento y el nivel de conocimientos en pacientes con hipertensión arterial son factores claves para controlar esta afección y evitar complicaciones. Objetivos: determinar el grado de adherencia al tratamiento, el nivel de conocimientos y comorbilidades en pacientes con hipertensión arterial de un área urbana de Asunción, Paraguay, en 2022. Metodología: se aplicó un diseño observacional, descriptivo, transversal. Se incluyeron varones y mujeres mayores de 18 años, conocidos portadores de hipertensión arterial, que residen en el barrio Sajonia entre mayo y octubre del 2022. Los datos fueron obtenidos con entrevistas realizadas casa por casa. Se midieron variables demográficas, el nivel de adherencia con el cuestionario de Morisky Green y el de conocimientos sobre la enfermedad con el cuestionario de Batalla. La investigación fue aprobada por el Comité de ética de la Universidad Privada del Este, Paraguay. Resultados: participaron del estudio 425 sujetos, con predominio del sexo femenino (61,1%). La diabetes mellitus fue referida en 28,9% de los entrevistados. El cuestionario de Morisky Green detectó que 60% de los sujetos olvida de tomar su medicación, 25% no la toma en el horario indicado, 29% de la toma si se siente bien y 44% deja de tomarla si siente efectos indeseables. El cuestionario de Batalla halló 7% cree que la hipertensión arterial no es para toda la vida, 9% cree que la afección no se controla con dieta y medicación, y 5,8% no pudo referir al menos un órgano blanco. Conclusión: la adherencia al tratamiento de la hipertensión arterial y el nivel de conocimientos sobre esta afección no fue adecuada.

https://doi.org/10.18004/rvspmi/2312-3893/2023.10.01.11

Spatial, spatio-temporal, and origin-destination flow analyses of patients with severe acute respiratory syndrome hospitalized for COVID-19 in Southeastern Brazil, 2020-2021
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Palasio, Raquel Gardini Sanches

; Lorenz, Camila

; Lucas, Pamella Cristina de Carvalho

; Nielsen, Lucca

; Masuda, Eliana Tiemi

; Trevisan, Camila Martins

; Cortez, André Lazzeri

; Monteiro, Pedro de Campos Mello

; Simões, Caroline Salomão

; Ferreira, Patrícia Marques

; Pellini, Alessandra Cristina Guedes

; Yu, Ana Lucia Frugis

; Carvalhanas, Telma Regina Marques

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volumen 65 elocation e6

Resumen: En | Texto: En | PDF: En

ABSTRACT Brazil experienced one of the fastest increasing numbers of coronavirus disease (COVID-19) cases worldwide. The Sao Paulo State (SPS) reported a high incidence, particularly in Sao Paulo municipality. This study aimed to identify clusters of incidence and mortality of hospitalized patients with severe acute respiratory syndrome for COVID-19 in the SPS, in 2020–2021, and describe the origin flow pattern of the cases. Cases and mortality risk area clusters were identified through different analyses (spatial clusters, spatio-temporal clusters, and spatial variation in temporal trends) by weighting areas. Ripley’s K12-function verified the spatial dependence between the cases and infrastructure. There were 517,935 reported cases, with 152,128 cases resulting in death. Of the 470,441 patients hospitalized and residing in the SPS, 357,526 remained in the original municipality, while 112,915 did not. Cases and death clusters were identified in the Sao Paulo metropolitan region (SPMR) and Baixada Santista region in the first study period, and in the SPMR and the Campinas, Sao Jose do Rio Preto, Barretos, and Sorocaba municipalities during the second period. We highlight the priority areas for control and surveillance actions for COVID-19, which could lead to better outcomes in future outbreaks.

https://doi.org/10.1590/s1678-9946202365006

Conhecimentos sobre a doença de Chagas entre escolares de dois municípios de Minas Gerais, Brasil
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Oliveira, Nathália Werneck Cézar de

; Salles, Helen Caroline Rocha de

; Vicq, Filipe De Mello De

; Ferreira, Raquel Aparecida

; Mambrini, Juliana Vaz de Melo

; Diotaiuti, Liléia

; Dias, João Carlos Pinto

; Souza, Rita de Cássia Moreira de

Cadernos Saúde Coletiva

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2023, Volumen 31 Nº 4 elocation e310400121

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background: In Brazil, entomological surveillance of Chagas disease (ChD) is based on community participation, which notifies the presence of vectors inside their homes. Thus, the sustainability of this control measure depends on the knowledge of the population about the vectors. Objective: To evaluate the knowledge of schoolchildren about ChD in the municipalities of Itatiaiuçu (active surveillance) and Sabará (inactive surveillance). Method: A semi-structured questionnaire was given to students enrolled in two high schools in Sabará (rural and urban) and one in Itatiaiuçu (urban). Results: In general, students living in Sabará demonstrated only limited knowledge about vectors, pathogens, transmission, and disease (with no significant differences between the schools in urban and rural areas). Similarly, the schoolchildren in Itatiaiuçu, despite living in an area of active surveillance, also did not have a fully satisfactory knowledge of ChD. Conclusions: The results emphasize the lack of information about ChD, both in relation to academic knowledge and the education campaigns established by the program. Improvements in educational interventions to raise community awareness and promote knowledge about ChD are necessary and vital for maintaining vigilance against ChD over space and time.

Resumo Introdução: No Brasil, a vigilância entomológica da doença de Chagas (DCh) é respaldada na participação comunitária, que notifica a presença dos vetores nas habitações. Assim, a sustentabilidade desta medida de controle depende do conhecimento da população sobre os vetores. Objetivo: Avaliar o conhecimento de escolares sobre a doença de Chagas nos municípios mineiros de Itatiaiuçu (vigilância ativa) e Sabará (vigilância inativa). Método: Questionário semiestruturado foi aplicado para alunos matriculados no ensino médio em duas escolas de Sabará (rural e urbana) e uma em Itatiaiuçu (urbana). Resultados: Em geral, os alunos residentes em Sabará demonstraram conhecimento limitado acerca dos vetores, patógeno, transmissão e doença (sem diferenças relevantes quanto à localização entre área urbana e rural), quando comparados aos residentes em Itatiaiuçu, que apesar de ter uma vigilância mais atuante, também não apresentaram conhecimento totalmente satisfatório. Conclusões: Os resultados enfatizam a carência de informações sobre a DCh tanto em relação ao conhecimento acadêmico quanto às campanhas de educação firmadas pelo programa. Ações educativas para sensibilizar a comunidade e promover o conhecimento sobre esta doença mostram-se necessárias e fundamentais para a manutenção da vigilância ao longo do tempo e espaço.

https://doi.org/10.1590/1414-462x2023310400121

A novel temporary hybrid mental health service in Brazil during the COVID-19 pandemic
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Generoso, Marcelo Bruno

; Pelissoni, Amanda Menon

; de Sousa, Ana Alice Freire

; Favaro, Raquel do Lago

; Mazaferro, Paulo

; Calzavara, Mariana Bendlin

; de Mello, Andrea de Abreu Feijó

Trends in Psychiatry and Psychotherapy

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2023, Volumen 45 elocation e20220472

Resumen: En | Texto: En | PDF: En

https://doi.org/10.47626/2237-6089-2022-0472

Running velocity at maximum oxygen uptake and at maximum effort: important variables for female military pentathlon
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Mainenti, Míriam Raquel Meira

; Vigário, Patrícia dos Santos

; Batista, Hugo Brito

; Bastos, Luiz Fernando Valverde

; Mello, Danielli Braga de

Motriz: Revista de Educação Física

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2022, Volumen 28 Nº spe1 elocation e10220018921

Resumen: En | Texto: En | PDF: En

Abstract Aim: to correlate cardiopulmonary capacity widely used variables with athletic performance in 4 km cross country race, in elite female military pentathlon athletes. Methods: Five military pentathlon athletes from Brazilian team with 27.5 [25.0; 29.3] years old underwent an incremental ramp treadmill test to determine VO2max, vVO2max (velocity of initial VO2 plateau), maximum velocity, and these same variables in anaerobic threshold. Furthermore, the performance obtained on the cross-country race of the last trial before the world military games was recorded. Spearman’s correlations were used to investigate the association between cardiopulmonary variables and athletic performance (p < 0.05). Results: The athletes exhibited a median total body weight of 64.3 [60.9; 66.6] kg and height of 1.75 [1.66; 1.76] cm. Race performance was positively correlated with vVO2max (r = 0.98, very strong correlation) and maximum velocity reached (r = 0.95, very strong correlation). The remaining cardiopulmonary variables did not show similar behavior, with r varying between -0.26 and 0.44. Conclusion: Maximum velocity and vVO2max indicators are directly related to athletic performance in the 4 km cross country race of elite female military pentathlon athletes. Thus, the technical team must pay particular attention to athletic performance in these cardiopulmonary variables in both the selection of new athletes and the identification of the effectiveness of applied training strategies.

https://doi.org/10.1590/s1980-657420220018921

10.

Female military pentathlon athletes and scientific research - a mini-review
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Mainenti, Míriam Raquel Meira

; Miarka, Bianca

; Loyola, Marcos Vinícius Marques

; Santos, Lucas Vieira Coelho dos

; Mello, Danielli Braga de

Motriz: Revista de Educação Física

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2022, Volumen 28 Nº spe1 elocation e10220017921

Resumen: En | Texto: En | PDF: En

Abstract Aim: to compile existing information in the scientific literature on female military pentathlon athletes. Methods: searches were performed on Pubmed/Medline, Scielo, and Scholar Google databases with specific strings in English and Portuguese. Results: military pentathlon is a discipline that comprises five events, namely: rifle shooting, obstacle run, obstacle swimming, throwing, and cross country running. Our search initially identified 275 records, which were reduced to the final list of 14 after the eligibility criteria analysis was performed in two phases: title + abstract reading and full-text reading. The first record was published in 2007 (recent field of study) and most studies were cross-sectional ones (scarcity of experimental studies), investigating outcomes like psychological, anthropometric, biochemical, biomechanics, cardiopulmonary, nutritional, skin temperature, performance, and prevalence of injury. The female military pentathlon athletes present low values of body fat, energy intake, and high weekly training volume, so professionals must be aware to prevent relative energy deficiency in sports (RED-S) syndrome. The obstacle run was the most investigated event, with lower blood lactate and skin temperature for women athletes. It was also observed that anthropometric, muscle power, and cardiopulmonary variables are well correlated with athletic performance and in some studies, these correlations were stronger for female athletes. Conclusion: scientific research with female military pentathlon athletes is still incipient, especially for experimental design researches, which are highly encouraged in future studies.

https://doi.org/10.1590/s1980-657420220017921

11.

Country-specific lockdown measures in response to the COVID-19 pandemic and its impact on tuberculosis control: a global study
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Migliori, Giovanni Battista

; Thong, Pei Min

; Alffenaar, Jan-Willem

; Denholm, Justin

; Tadolini, Marina

; Alyaquobi, Fatma

; Al-Abri, Seif

; Blanc, François-Xavier

; Buonsenso, Danilo

; Chakaya, Jeremiah

; Cho, Jin-Gun

; Codecasa, Luigi Ruffo

; Danila, Edvardas

; Duarte, Raquel

; Dukpa, Rada

; García-García, José-María

; Gualano, Gina

; Kurhasani, Xhevat

; Manika, Katerina

; Mello, Fernanda Carvalho de Queiroz

; Pahl, Kristin

; Rendon, Adrian

; Sotgiu, Giovanni

; Souleymane, Mahamadou Bassirou

; Thomas, Tania A.

; Tiberi, Simon

; Kunst, Heinke

; Udwadia, Zarir F.

; Goletti, Delia

; Centis, Rosella

; D’Ambrosio, Lia

; Silva, Denise Rossato

Jornal Brasileiro de Pneumologia

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2022, Volumen 48 Nº 2 elocation e20220087

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo deste estudo foi descrever as medidas de confinamento específicas de cada país e os indicadores de tuberculose coletados durante o primeiro ano da pandemia de COVID-19. Dados referentes a confinamento/restrições sociais (uso obrigatório de máscaras faciais e higiene obrigatória das mãos; restrições a viagens internacionais e locais; restrições a visitas familiares e fechamento das escolas) foram coletados de 24 países em cinco continentes. A maioria dos países implantou múltiplos confinamentos, com reabertura parcial ou total. Houve uma redução geral dos casos de tuberculose ativa, tuberculose resistente e tuberculose latente. Embora os confinamentos nacionais tenham sido eficazes na contenção dos casos de COVID-19, vários indicadores de tuberculose foram afetados durante a pandemia.

ABSTRACT The objective of this study was to describe country-specific lockdown measures and tuberculosis indicators collected during the first year of the COVID-19 pandemic. Data on lockdown/social restrictions (compulsory face masks and hand hygiene; international and local travel restrictions; restrictions to family visits, and school closures) were collected from 24 countries spanning five continents. The majority of the countries implemented multiple lockdowns with partial or full reopening. There was an overall decrease in active tuberculosis, drug-resistant tuberculosis, and latent tuberculosis cases. Although national lockdowns were effective in containing COVID-19 cases, several indicators of tuberculosis were affected during the pandemic.

https://doi.org/10.36416/1806-3756/e20220087

12.

Desenvolvimento infantil e visita domiciliar na primeira infância: mapa conceitual
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Hilário, Jeniffer Stephanie Marques

; Henrique, Nayara Cristina Pereira

; Santos, Jaqueline Silva

; Andrade, Raquel Dully

; Fracolli, Lislaine Aparecida

; Mello, Débora Falleiros de

Acta Paulista de Enfermagem

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2022, Volumen 35 elocation eAPE003652

Resumen: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Identificar e analisar as evidências científicas sobre visita domiciliar (VD) à crianças menores de seis anos de idade, na perspectiva da promoção da saúde e do desenvolvimento na primeira infância. Métodos Revisão integrativa da literatura, nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde, Cumulative Index to Nursing and Allied Health Literature, Scopus, Web of Science, PubMed e PsycINFO. Foram incluídos estudos científicos originais quantitativos, qualitativos e método misto, publicados entre 2016 e 2019, idiomas português e inglês, foco central de VD na primeira infância, e excluídos estudos de revisão, teses, dissertações, livros e capítulos de livros, resumos e editoriais publicados. Análise dos dados pautada na estratégia do mapa conceitual em teia de aranha, com síntese integrativa de 19 estudos selecionados. Resultados As evidências científicas mostram a importância da estratégia de VD na primeira infância, com características das ações oferecidas nessa abordagem. Os conteúdos e abordagens das VD foram identificados como criadores de condições propícias para retratar temas, situações e necessidades da primeira infância, essenciais à vitalidade da saúde e estímulo ao bom desenvolvimento nos primeiros anos de vida. Conclusão A síntese integrativa identificou que a VD é uma valiosa estratégia para a primeira infância, indicando os benefícios ao desenvolvimento da criança e de seus cuidadores, para promover saúde e prevenir agravos. O Mapa Conceitual elaborado sugere uma gama de elementos relevantes que qualifica a VD na primeira infância com contribuições à atenção integral à saúde da criança e às boas práticas parentais.

Abstract Objective To identify and analyze the scientific evidence on home visits (HV) to children under six years of age, from the perspective of promoting health and early childhood development. Methods This is an integrative literature review, in the Latin American and Caribbean Literature in Health Sciences, Cumulative Index to Nursing and Allied Health Literature, Scopus, Web of Science, PubMed and PsycINFO databases. Quantitative, qualitative and mixed method original scientific studies, published between 2016 and 2019, in Portuguese and English, central focus of HV in early childhood, were included, and review studies, theses, dissertations, books and book chapters, abstracts and editorials were excluded published. Data analysis based on the concept map strategy in a spider’s web, with an integrative synthesis of 19 selected studies. Results Scientific evidence shows the importance of the HV strategy in early childhood, with characteristics of the actions offered in this approach. The contents and approaches of HV were identified as creating favorable conditions to portray themes, situations and needs of early childhood, essential to health vitality and encourage good development in the first years of life. Conclusion The integrative synthesis identified that HV is a valuable strategy for early childhood, indicating the benefits to child development and their caregivers to promote health and prevent injuries. The conceptual map developed suggests a range of relevant elements that qualify HV in early childhood with contributions to comprehensive child health care and good parenting practices.

Resumen Objetivo Identificar y analizar las evidencias científicas sobre la visita domiciliaria (VD) a los niños menores de seis años de edad, en la perspectiva de la promoción de la salud y del desarrollo en la primera infancia. Métodos Revisión integradora de la literatura en las bases de datos Literatura Latino-Americana e do Caribe em Ciências da Saúde, Cumulative Index to Nursing and Allied Health Literature, Scopus, Web of Science, PubMed y PsycINFO. Se incluyeron estudios científicos originales, cuantitativos, cualitativos y método mixto, publicados entre 2016 y 2019, idiomas portugués e inglés, enfoque central de VD en la primera infancia, y excluidos estudios de revisión, tesis, disertaciones, libros y capítulos de libros, resúmenes y editoriales publicados. Análisis de los datos orientado en la estrategia del mapa conceptual de telaraña, con síntesis integrativos de 19 estudios seleccionados. Resultados Las evidencias científicas muestran la importancia de la estrategia de VD en la primera infancia, con características de las acciones que se ofrecen en ese enfoque. Los contenidos y enfoques de las VD fueron identificados como los creadores de condiciones adecuadas para retratar temas, situaciones y necesidades de la primera infancia, esenciales para la vitalidad de la salud y el estímulo al buen desarrollo en los primeros años de vida. Conclusión La síntesis integrativa identificó que la VD es una estrategia valiosa para la primera infancia, indicando los beneficios para el desarrollo del niño y de sus cuidadores, para promover la salud y prevenir agravamientos. El Mapa Conceptual elaborado sugiere una gama de elementos relevantes que califica a VD en la primera infancia con contribuciones a la atención integral a la salud del niño y a las buenas prácticas parentales.

https://doi.org/10.37689/acta-ape/2022ar03653

13.

Development and evaluation of topical formulations that contain hydroethanolic extract from Schinus terebinthifolia against HSV-1 infection
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Nocchi, Samara Requena

; Ferreira, Lilian dos Anjos Oliveira

; Castro-Hoshino, Lidiane Vizioli de

; Truiti, Maria da Conceição Torrado

; Natali, Maria Raquel Marçal

; Mello, João Carlos Palazzo de

; Baesso, Mauro Luciano

; Dias Filho, Benedito Prado

; Nakamura, Celso Vataru

; Ueda-Nakamura, Tânia

Brazilian Journal of Pharmaceutical Sciences

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2022, Volumen 58 elocation e18637

Resumen: En | Texto: En | PDF: En

Abstract The therapeutic drugs to treat Herpes simplex virus (HSV) infections have toxic side effects and there has been an emergence of drug-resistant strains. Therefore, the search for new treatments for HSV infections is mounting. In the present study, semi-solid formulations containing a crude hydroethanolic extract (CHE) from Schinus terebinthifolia were developed. Skin irritation, cutaneous permeation, and in vivo therapeutic efficacy of the formulations were investigated. Treatment with the ointment formulations did not result in any signs of skin irritation while the emulsions increased the thickness of the epidermis in Swiss mice. The cutaneous permeation test indicated that the CHE incorporated in the formulations permeated through the skin layers and was present in the epidermis and dermis even 3 h after topical application. In vivo antiviral activity in BALB/c mice treated with the CHE ointments was better than those treated with the CHE emulsions and did not significantly differ from an acyclovir-treated group. Taken together, this suggests that the incorporation of CHE in the ointment may be a potential candidate for the alternative topical treatment of herpetic lesions.

https://doi.org/10.1590/s2175-97902020000318637

14.

Depression and suicide risk during the Covid-19 pandemic at a Brazilian public health psychosocial addiction care center: a preliminary report
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de Moura, Patricia Tejera

; Rockenbach, Camila Auth

; Mendes, Caroline da Rosa

; Mendes, Giovani Unterberger

; Ghiggi, Letícia Abruzzi

; Diel, Marciane

; Martini, Patrícia

; Camozzato Filho, Plauto

; de Castro, Raquel Scafuto Barbosa

; Mello de Mello, Rita

; Kovalski, Rossana

; Mendes Filho, Vauto Alves

; Mosqueiro, Bruno Paz

Trends in Psychiatry and Psychotherapy

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2022, Volumen 44 elocation e20210259

Resumen: En | Texto: En | PDF: En

Abstract Objective To evaluate the impact of the Covid-19 pandemic on depressive symptoms and suicide risk among patients receiving treatment at a Public Health Psychosocial Addiction Care Center (CAPS AD III) in Porto Alegre, Brazil. Methods Questions from the Coronavirus Health Impact Survey (CRISIS) translated into Brazilian Portuguese were used to evaluate 70 patients’ perceptions of and behaviors during the Covid-19 pandemic. Validated Brazilian versions of the Patient Health Questionnaire (PHQ-9) and the General Anxiety Disorder-7 (GAD-7) were used to evaluate the severity of depressive symptoms, suicide risk, and anxiety symptoms. A multiple logistic regression model was used to evaluate predictors of suicide risk in the sample. Results Around 70% of patients reported moderate depressive symptoms and 30% reported severe depressive symptoms, 17% of patients reported having thoughts of suicide or death on more than half of days and 10% reported having them daily. The logistic regression model identified history of alcohol use as the main predictor of suicide risk in (OR 13.0, p = 0.03). Conclusions Individuals with a history of alcohol consumption had significantly higher suicide risk scores at a psychosocial public health care center in Brazil during the Covid-19 pandemic. This result may be important for devising better strategies and interventions to support this specific population profile.

https://doi.org/10.47626/2237-6089-2021-0259

15.

A organização do trabalho pedagógico da Educação Física com crianças em tratamento oncológico
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Trindade, Luísa Helmer

; Barbosa, Raquel Firmino Magalhães

; Mello, André da Silva

Revista Brasileira de Ciências do Esporte

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2022, Volumen 44 elocation e20220084

Resumen: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Discute o trabalho pedagógico de professores de Educação Física com crianças em tratamento oncológico, considerando as agências, as autorias e as produções culturais dos infantis. Trata-se de uma Pesquisa-Ação Colaborativa, desenvolvida com 61 crianças entre 4 e 12 anos. Os dados produzidos pela observação participante e registrados em diário de campo foram sistematizados em três categorias: planejamento em conjunto, tempo do brincar e agências infantis. Os resultados apontam para a construção coletiva do planejamento e para o reconhecimento das crianças como agentes de si, produtoras de cultura e protagonistas em seus processos de socialização, dando visibilidade ao que é criado e ressignificado por elas.

ABSTRACT Discusses the pedagogical work of Physical Education teachers with children with cancer, considering the agencies, authorship, and cultural productions of children. This is a Collaborative Action Research, developed between 2019 and 2021, with 61 children between 4 and 12 years old. The data produced by observation and recorded in a field diary were systematized into three categories: joint planning, playtime, and children's agencies. The results point to the collective construction of planning and the recognition of children as agents of themselves, producers of culture, and protagonists in their socialization processes, giving visibility to what is created and re-signified by them.

RESUMEN Discute el trabajo pedagógico de los profesores de Educación Física con niños con cáncer, considerando los organismos, la autoría y las producciones culturales de los niños. Se trata de una Investigación Acción Colaborativa, desarrollada entre 2019 y 2021, con 61 niños entre 4 y 12 años. Los datos producidos por la observación y registrados en un diario de campo fueron sistematizados en tres categorías: planificación conjunta, tiempo de juego y agencias infantiles. Los resultados apuntan para la construcción colectiva de la planificación y el reconocimiento de los niños y niñas como agentes de sí mismos, productores de cultura y protagonistas de sus procesos de socialización, dando visibilidad a lo creado y resignificado por ellos.

https://doi.org/10.1590/rbce.44.e20220084

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