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Cancer is one of the major causes of death worldwide, and breast cancer is the most prevalent and deadly type among women. Despite the side effects and the phenomena of chemoresistance associated with the drugs involved, chemotherapy remains the main therapeutic strategy to combat and control breast cancer. Therefore, several new classes of compounds against breast cancer have been explored, in an effort to identify new drug candidates with alternative mechanisms of action. The principal results of such exploration, focusing on caged xanthones, thiosemicarbazones and photosensitizers, are presented in this review, along with the main aspects of the drug discovery process against breast cancer. More specifically, the design, structure-activity relationship investigations and anti-breast cancer properties of these three classes are described and discussed in this work. worldwide women involved Therefore explored action exploration xanthones photosensitizers review specifically design structureactivity structure activity antibreast anti work

https://doi.org/10.21577/0103-5053.20230128

Evaluation of an automatized AMBU ESSI-1 INC designed at the Instituto Nacional de Cardiología Ignacio Chávez
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Abundes-Velasco, Arturo

; Sánchez-Pérez, Efraín

; Jiménez-Rodríguez, Gian M.

; Molina-Méndez, Francisco J.

; Herrera-Elizalde, Rafael

; Pulido-Zamudio, Tomás

; Álvarez-Rosales, Humberto

; Villegas-Juache, Juan

; Aceves-Díaz-González, Sebastián

; Parra-Rodríguez, David A.

; Cruz-Enríquez, Francisco J.

; Cobos-Reyes, Farid A.

; Aguilar-Torres, Eduardo A.

; Islas-Navarro, Enid A.

; Nuñez-Gómez, José C.

; Peña-Duque, Marco A.

Archivos de cardiología de México

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Dic 2023, Volumen 93 Nº 4 Paginas 391 - 397

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Objetivo: Evaluar un dispositivo automatizado para la asistencia ventilatoria basado en un AMBU manufacturado en Marzo del 2020. Métodos: El ESSI-1 INC fue evaluado por medio de parámetros fisiológicos y mecánica pulmonar a través de pruebas de espirómetro compensatorios (TISSOT); pulmón artificial (Modelo 5600i Dual Adult PNEU VIEW SYSTEM); así como su desempeño comparado a la máquina de anestesia (AEONMED 7500) en modelos porcinos, midiendo criterios ventilatorios, hemodinámicos y gasométricos. Resultados: Este equipo (ESSI-1 INC) fue exitosamente probado por modelos mecánicos y biológicos, tales como cerdos donde su desempeño fue evaluado en términos de la variabilidad del volumen tidal, frecuencia ventilatoria, y relación I/E versus el desempeño manual de dos médicos. Todos los resultados finalizaron como se esperaba de forma satisfactoria. Conclusiones: Es un equipo seguro y efectivo, el cual debería ser probado y usado en distintas condiciones clínicas para estandarizar la seguridad ventilatoria y cuidado de pacientes que lo requieran.

Abstract Objective: The objectives of this study were to evaluate an automated device for ventilatory support based on AMBU manufactured in March 2020. Methods: The ESSI-1 INC was evaluated through pulmonary mechanics and physiology parameters through compensatory spirometer tests (TISSOTs), and an artificial lung Model5600i Dual Adult PNEU VIEW SYSTEM; it was also compared to the anesthetic ventilatory support equipment (AEONMED 7500) in porcine models, measuring ventilatory, hemodynamic and gasometric parameters. Results: This equipment (ESSI-1 INC) was successfully tested by mechanical and biological models, such as pigs in which its performance was evaluated in terms of variability of tidal volume, ventilation frequency, and I/E relationship versus the manual performance of two medical interns. All the results turned out as expected and were satisfactory. Conclusions: It is safe and effective equipment and should be tested and used in diverse clinical conditions to standardize the ventilatory safety and care of patients who require it.

https://doi.org/10.24875/acm.2200004

Pericapsular Nerve Group (PENG) block versus fascia iliaca compartment (FI) block for hip surgery: a systematic review and meta-analysis of randomized controlled trials
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Andrade, Priscila P.

; Lombardi, Rafael A.

; Marques, Isabela R.

; Braga, Anna Carla Di Napoli Andrade e

; Isaias, Beatrice R.S.

; Heiser, Nicholas E.

Brazilian Journal of Anesthesiology

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Dic 2023, Volumen 73 Nº 6 Paginas 794 - 809

Resumen: En | Texto: En | PDF: En

Abstract Background: This study compares Fascia Iliaca compartment (FI) block and Pericapsular Nerve Group (PENG) block for hip surgery. Methods: Pubmed, Embase and Cochrane were systematically searched in April 2022. Inclusion criteria were: Randomized Controlled Trials (RCTs); comparing PENG block versus FI block for hip surgery; patients over 18 years of age; and reporting outcomes immediately postoperative. We excluded studies with overlapped populations and without a head-to-head comparison of the PENG block vs. FI block. Mean-Difference (MD) with 95% Confidence Intervals (CI) were pooled. Trial Sequential Analyses (TSA) were performed to assess inconsistency. Quality assessment and risk of bias were performed according to Cochrane recommendations. Results: Eight RCTs comprising 384 patients were included, of whom 196 (51%) underwent PENG block. After hip surgery, PENG block reduced static pain score at 12h post-surgery (MD = 0.61 mm; 95% CI 1.12 to -0.09; p = 0.02) and cumulative postoperative oral morphine consumption in the first 24h (MD = -6.93 mg; 95% CI -13.60 to -0.25; p = 0.04) compared with the FI group. However, no differences were found between the two techniques regarding dynamic and static pain scores at 6 h or 24 h post-surgery, or in the time to the first analgesic rescue after surgery. Conclusion: The findings suggest that PENG block reduced opioid consumption in the first 24 h after surgery and reduced pain scores at rest at 12 h post-surgery. Further research is needed to fully understand the effects of the PENG block and its potential benefits compared to FI block. PROSPERO registration: CRD42022339628 PROSPERO registration: https://www.crd.york.ac.uk/prospero/display_record.php? RecordID=339628

https://doi.org/10.1016/j.bjane.2023.07.007

Long-term oncological and surgical outcomes after Video Endoscopic Inguinal Lymphadenectomy (VEIL) in patients with penile cancer
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Tobias-Machado, Marcos

; Ornellas, Antonio A.

; Hidaka, Alexandre K.

; Medina, Luis G.

; Mattos, Pablo A. L.

; Besio, Ruben S.

; Abreu, Diego

; Castro, Pedro R.

; Nishimoto, Ricardo H.

; Astigueta, Juan

; Dourado, Aurus

; Machado, Roberto D.

; Magnabosco, Wesley J.

; Corona-Montes, Victor

; Villoldo, Gustavo M.

; Zampolli, Hamilton C.

; Taha, Anis

; Auad, Pericles R.

; Faria, Eliney F.

; Arantes, Paulo B. O.

; Tavares, Alessandro

; Nascimento, Francisco S. M. S.

; Brazão Jr., Eder S.

; Rocha, Maurício M.

; Costa, Walter H.

; Panico, Vinicius

; Reis, Leonardo O.

; Almeida-Carrera, Roberto J.

; Silva, Rafael C.

; Zequi, Stênio C.

; Calixto, José R. R.

; Sotelo, Rene

International braz j urol

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Oct 2023, Volumen 49 Nº 5 Paginas 580 - 589

Resumen: En | Texto: En | PDF: En

ABSTRACT Objective: To report outcomes from the largest multicenter series of penile cancer patients undergoing video endoscopic inguinal lymphadenectomy (VEIL). Materials and Methods: Retrospective multicenter analysis. Authors of 21 centers from the Penile Cancer Collaborative Coalition-Latin America (PeC-LA) were included. All centers performed the procedure following the same previously described standardized technique. Inclusion criteria included penile cancer patients with no palpable lymph nodes and intermediate/high-risk disease and those with non-fixed palpable lymph nodes less than 4 cm in diameter. Categorical variables are shown as percentages and frequencies whereas continuous variables as mean and range. Results: From 2006 to 2020, 210 VEIL procedures were performed in 105 patients. Mean age was 58 (45-68) years old. Mean operative time was 90 minutes (60-120). Mean lymph node yield was 10 nodes (6-16). Complication rate was 15.7%, including severe complications in 1.9% of procedures. Lymphatic and skin complications were noted in 8.6 and 4.8% of patients, respectively. Histopathological analysis revealed lymph node involvement in 26.7% of patients with non-palpable nodes. Inguinal recurrence was observed in 2.8% of patients. 10y- overall survival was 74.2% and 10-y cancer specific survival was 84.8%. CSS for pN0, pN1, pN2 and pN3 were 100%, 82.4%, 72.7% and 9.1%, respectively. Conclusion: VEIL seems to offer appropriate long term oncological control with minimal morbidity. In the absence of non-invasive stratification measures such as dynamic sentinel node biopsy, VEIL emerged as the alternative for the management of non-bulky lymph nodes in penile cancer.

https://doi.org/10.1590/s1677-5538.ibju.2023.0065

Interactions between ants and mealybugs in sugarcane: species and effects on insect pests
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Marchiori, Johnatan J. de P.

; Almeida, Fábio S. de

; Mayhé-Nunes, Antônio J.

; Nobre, Rafael V. L.

; Paulo, Hágabo H. de

Revista Caatinga

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Sep 2023, Volumen 36 Nº 3 Paginas 731 - 739

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The objective of this work was to evaluate ant species interacting with mealybugs in sugarcane plantations, the frequency of occurrence, and the effects of the interaction with ants on mealybug population size. The data was collected in a sugarcane plantation area in Seropedica, Rio de Janeiro, Brazil. The insect species were collected from 70 thoroughly inspected sugarcane plants and the nature and frequency of the interactions were evaluated. The effect of the interaction with ants on mealybug abundance was evaluated by counting the number of adult females of each mealybug species on ten plants isolated and ten plants not isolated from ants. Two mealybug species were collected: Aclerda takahashii (Kuwana, 1932) and Saccharicoccus sacchari (Cockerell, 1895). Ten and seven ant species were found interacting with A. takahashii and S. sacchari, respectively, which were distributed among six genera; the most frequent genera were Crematogaster and Camponotus. Three ant species interacted exclusively with A. takahashii, whereas the others interacted with both mealybug species. The abundance of A. takahashii females was significantly higher on non-isolated than on isolated plants (Paired t-test; t = 2.34; p = 0.04). However, no significant difference in S. sacchari abundance was found between isolated and non-isolated plants (t = 0.27; p = 0.8), nor for the two species combined (t = 1.9; p = 0.09). Thus, ant species that interact with mealybugs in sugarcane plantations cause increases in A. takahashii populations which, at a larger scale, can reduce crop yield.

RESUMO O objetivo desse trabalho foi realizar o levantamento das espécies de formigas que apresentam interações com cochonilhas em plantios de cana-de-açúcar, registrando a frequência de ocorrência e o efeito da interação com as formigas sobre as populações de cochonilhas. A pesquisa foi realizada em plantio de cana-de-açúcar no município de Seropédica, estado do Rio de Janeiro. Os insetos foram coletados em 70 plantas de cana-de-açúcar, observando-se a natureza das interações e a sua frequência. Para avaliar a influência da interação das formigas sobre a abundância das cochonilhas, foi obtido o número de fêmeas adultas de cada espécie de cochonilha em dez plantas isoladas de formigas e dez não isoladas. Foram coletadas duas espécies de cochonilhas: Aclerda takahashii (Kuwana, 1932) e Saccharicoccus sacchari (Cockerell, 1895). Dez espécies de formigas foram observadas interagindo com A. takahashii, e sete espécies com S. sacchari, distribuídas em seis gêneros, sendo os mais frequentes Crematogaster e Camponotus. Três espécies de formigas interagiram somente com A. takahashii, as demais interagiram com ambas espécies de cochonilha. A abundância de fêmeas de A. takahashii foi significativamente maior nas plantas não isoladas que nas isoladas (t= 2,34; p = 0,04). Não foi observada diferença significativa na abundância de S. sacchari entre plantas isoladas e não isoladas (t= 0,27; p = 0,8), e para as duas espécies em conjunto (t= 1,9; p= 0,09). As espécies de formigas que interagem com cochonilhas em cana-de-açúcar provocam o aumento da população de A. takahashii, o que em maior escala pode reduzir a produtividade.

https://doi.org/10.1590/1983-21252023v36n325rc

Larvicidal Activity of Calcium Alginate Microcapsules Containing Clove Essential Oil Obtained by Microfluidics
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Condé, Débora T.

; Mendes, Luiza A.

; Ramos, Guilherme P.

; Silva, Rafael R. A.

; Teixeira, Alvaro V. N. C.

; Teixeira, Róbson Ricardo

; Martins, Gustavo F.

; Cerceau, Cristiane I.

; Lopes, Renata P.

Journal of the Brazilian Chemical Society

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Ago 2023, Volumen 34 Nº 8 Paginas 1166 - 1174

Resumen: En | Texto: En | PDF: En

Essential oils (EO) have diverse applications, such as antibacterial and antifungal activity. However, they are susceptible to oxidation in the presence of air, light, and moisture. In addition, they are thermally unstable. In this sense, it is necessary to develop techniques to increase the lifespan of EO. In this work, EO was obtained from cloves and characterized by different techniques. The major compounds found were eugenol (83%), eugenol acetate (9%), and β-caryophyllene (8%). The EO was encapsulated by extrusion using a microfluidic device. The sodium alginate was used as wall material, and the CaCl2 solution was used as a crosslinking agent. The microcapsule presented sizes of 164.7 ± 0.3 μm, with an encapsulation yield of 64 ± 14%. Functional characteristic groups of EO were observed in the microcapsule by infrared and Raman spectroscopies. The microcapsule increased the thermal decomposition of the EO from 162 to 230 °C. Release kinetics of the capsule was performed, with an equilibrium time of 72 h and release of 54% of the EO. Finally, the pure EO and encapsulated EO-microcapsules were applied in the Aedes aegypti larvae control, showing mean lethal concentration necessary to eliminate 50% (LC50) values of 74.4 and 96.9 μg mL-1 and lethal concentration necessary to eliminate 90% (LC90) of 106.2 and 133.3 μg mL-1 for pure EO and encapsulated EO, respectively. Therefore, it was concluded that these microcapsules have the potential for application in the Aedes aegypti larvae control.

https://doi.org/10.21577/0103-5053.20230029

Photochemical Pre-Treatment to Quantify Iron in Thin Films PreTreatment Pre Treatment
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Germscheidt, Rafael L.

; Morais, Cleiber C.

; Francischini, Danielle S.

; Arruda, Marco Aurélio Z.

; Bonacin, Juliano A.

Journal of the Brazilian Chemical Society

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Jul 2023, Volumen 34 Nº 7 Paginas 958 - 966

Resumen: En | Texto: En | PDF: En

Metal-based catalysts are indispensable in modern chemistry and one of the biggest challenges for industrial applications is to quantify their performance and stability. The metrics of performance can be obtained in terms of the turnover number and turnover frequency, and the stability might be associated with the leaching of the heterogeneous catalysts. Thus, metal quantification is the starting point to understand and evaluate the features of catalysts. Among the technologies for metal determination, spectrophotometric analysis stands out for being cheap and easy to perform. However, the challenge is the sample preparation to direct quantification from the heterogeneous materials. Herein, it is shown how important is the photochemical pre-treatment for the quantification of the total iron from heterogeneous thin films composed of iron-based materials. The photochemical approach was used to ensure a full dissociation of iron ions before the quantification. This method was revealed to be highly effective and precise, having a wide range of applications for different iron-based catalysts. Metalbased Metal based frequency Thus determination perform However materials Herein pretreatment pre treatment ironbased precise

https://doi.org/10.21577/0103-5053.20230008

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad limitada
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Cabrera-Miranda, Luis A.

; Lozano-Ruiz, Francisco J.

; Blake-Cerda, Mónika

; Corona-Cruz, José F.

; Sánchez-Reyes, Roberto

; Pérez-Álvarez, Sandra I.

; Díaz-García, Diego A.

; Álvarez-Bojórquez, Mario E.

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Bolaño-Guerra, Laura M.

; Maldonado-Magos, Federico

; Aldaco-Sarvide, Fernando

; Alvarado-Zermeño, Adriana

; Barajas-Figueroa, Luis J.

; Bautista-Aragón, Yolanda

; Bolaños-Morales, Francina V.

; Castillo-Ortega, Graciano

; Félix-Leyva, Jesús A.

; Gerson-Cwilich, Raquel

; Guzmán-de Alba, Enrique

; López-Galindo, Ángel A.

; Mariscal-Ramírez, Carlos

; Piñeiro-Retif, Rafael

; Ramos-Prudencio, Rubí

; Rodríguez-Cid, Jerónimo

; Silva-Bravo, Fernando

; Arrieta, Óscar

Gaceta mexicana de oncología

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Mar 2023, Volumen 22 Nº 1 Paginas 3 - 23

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP, enfermedad limitada, en México, basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración entre el Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensuaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad limitada, producto de las preguntas de trabajo. Se identificó y evaluó críticamente la evidencia científica que responde a cada una de dichas preguntas clínicas, antes de incorporarla a la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad limitada del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica en estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by rapid growth rate and development of distant metastases. Objectives: To guide and standardize the treatment of limited disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: Consensus recommendations were reached, both by the Delphi method and in remote meetings, for limited SCLC disease resulting from the same number of work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the guide. Conclusion: This guide provides clinical recommendations for the management of limited disease SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000121

Green Synthesis of Cellulose-Based Biofilms Doped with AgNPs with Antibacterial Activity
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Pereira, Arthur B. D.

; Silva, Rafael R. A.

; Marques, Clara S.

; Nascimento, Mayra Aparecida

; Soares, Nilda de Fatima F.

; Lopes, Renata P.

Journal of the Brazilian Chemical Society

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Mar 2023, Volumen 34 Nº 3 Paginas 366 - 376

Resumen: En | Texto: En | PDF: En

In this work, cellulose-based composite biofilms doped with silver nanoparticles (AgNPs) have been produced by eco-friendly process. The AgNPs were synthesized from Ilex paraguariensis with an average size of 45 nm, a characteristic plasmon band at 450 nm and zeta potential of -23 mV. The biofilm has been synthesized by casting method, using different volumes of AgNPs suspension with glycerol plasticizing agent (T6-T10) or not (T1-T5). The AgNPs were successfully incorporated into the biofilms, which was confirmed by scanning electron microscopy. The mechanical and optical structural and the antimicrobial properties of the biofilms have been determined. In the presence of AgNPs, the mechanical properties, thermal stability and water vapor barrier of the biofilms have not been altered. However, the addition of glycerol decreased the tensile strength and the modulus of elasticity, in addition to increasing the elongation of the biofilms and the water vapor barrier. The biofilm T10 showed a transmittance of ca. 10%, with high potential to be used as a UV light blocker. Finally, the biofilms doped with AgNPs showed activity against the bacterium Pseudomonas fluorescens. Given the above, this work presented a new biofilm with activity against the bacterium Pseudomonus fluorescens obtained by eco-friendly process.

https://doi.org/10.21577/0103-5053.20220114

10.

Perspectives in Training and Professional Practice of Cardiac Surgery in Latin America
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Marin-Cuartas, Mateo

; Vervoort, Dominique

; Contreras, Juan Roberto

; Garcia-Villareal, Ovidio A.

; Escobar, Alejandro

; Ferrari, Javier

; Quintana, Eduard

; Sadaba, Rafael

; Mestres, Carlos A.

; Carosella, Victorio C.

; Almeida, Rui M. S.

; Dayan, Victor

Brazilian Journal of Cardiovascular Surgery

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Feb 2023, Volumen 38 Nº 1 Paginas 1 - 14

Resumen: En | Texto: En | PDF: En

ABSTRACT Introduction: There is a lack of information about cardiac surgery training and professional practice in Latin American (LATAM) countries. This study is the first comparative analysis of cardiac surgical training and professional practice across LATAM and provides the fundamentals for future academic projects of the Latin American Association of Cardiac and Endovascular Surgery (LACES). Methods: International survey-based comparative analysis of the training and professional practice of cardiac surgeons across LATAM. Trainees (residents/fellows) and staf (graduated) surgeons from LATAM countries were included. Results: A total of 289 respondents (staf surgeons N=221 [76.5%]; residents/fellows N=68 [23.5%]) from 18 different countries participated in the survey. Most surgeons (N=92 [45.3%]) reported being unsatisfied with their salaries. Most respondents (N=181 [62.6%]) stated that it was difficult to obtain a leadership position, and 149 (73.8%) stated that it was difficult to find a job after completing training. Only half of the trainee respondents (N=32 [47.1%]) reported that their program had all resident spots occupied. Only 22.1% (N=15) of residents/fellows were satisfied with their training programs. The majority (N=205 [70.9%]) of respondents would choose cardiac surgery as their specialty again. Most surgeons (N=129 [63.9%]) and residents/fellows (N=52 [76.5%]) indicated that the establishment of a LATAM cardiac surgery board examination would be beneficial. Conclusion: Modernization and standardization of training, as well as greater access to opportunities, may be required in LATAM to increase professional satisfaction of cardiac surgeons and to reduce disparities in the specialty. Such changes may enhance the regional response to the dynamic challenges in the feld.

https://doi.org/10.21470/1678-9741-2022-0125

11.

Study of Catalytic Pyrolysis of Biomass Sorghum (Sorghum bicolor L. Moench) Using Design of Experiments and Surface Response Methodology
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Costa, Diego M.

; Simeone, Maria L. F.

; Parrella, Rafael A. C.

; Fortes, Isabel C. P.

Journal of the Brazilian Chemical Society

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Ene 2023, Volumen 34 Nº 1 Paginas 112 - 123

Resumen: En | Texto: En | PDF: En

This study proposes a screen of variables that have an influence on the modification of the bio-oil chemical composition as a unique critical quality attribute (CQA) throughout the pyrolytic process (zeolite, ZSM-5) by using a 24 full factorial design, followed by optimization through a response surface methodology (RSM) based on central composite design (CCD) involving samples of biomass sorghum BRS716 (Sorghum bicolor L. Moench). The pyrolysis of pure biomasses and the biomass impregnated with the catalyst was carried out in a vertical bench furnace at 500 °C. Screening design involved factor variation in two levels (-1 and +1) of four variables as critical process parameters (CPPs) such as furnace heating rate (°C min-1), nitrogen flow (mL min-1), amount of biomass (g), and catalyst (% m/m), leading to obtaining bio-oil. Thus, it was possible to create a response surface from these two variables (biomass and catalyst), in which a minimum critical point was reached. The production of a bio-oil rich in hydrocarbon compounds is possible, but a large amount of catalyst was required. Two analytical techniques based on gas chromatography coupled to mass spectrometry (GC-MS) and mid-infrared (MIR) spectroscopy, provided additional information to fully characterize bio-oil chemical composition.

https://doi.org/10.21577/0103-5053.20220093

12.

Diversidad y distribución de mosquitos (Diptera: Culicidae) en la frontera México-Guatemala
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Vázquez-Marroquín, Rafael

; Castañeda-Rivero, Francisco R.

; Chan-Chable, Rahuel J.

; Cruz-Ramos, Josué M. de la

; Espinoza-González, Carlos A.

; Ortega-Morales, Aldo I.

Revista mexicana de biodiversidad

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2023, Volumen 94 elocation e944063

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Se realizaron recolectas de mosquitos (Diptera: Culicidae) en el intradomicilio y peridomicilio a lo largo de la frontera Chiapas-Guatemala durante octubre-noviembre del 2018. Se recolectaron 4,439 especímenes pertenecientes a 2 subfamilias, 18 géneros y 41 especies, una de ellas Mansonia dyari (Belkin, Heinemann y Page, 1970) es un nuevo registro estatal para Chiapas. De las 41 especies recolectadas, 21 tienen importancia en salud pública, siendo algunas de ellas los principales vectores de malaria, dengue, fiebre amarilla, chikungunya, zika, mayaro, encefalitis equina venezolana, encefalitis equina del oeste y fiebre del valle del Rift. Culex quinquefasciatus y Aedes aegypti mostraron ser las más abundantes. En algunos casos, los municipios con mayor número de especies e individuos no fueron los más diversos y equitativos, con una alta disimilitud en la composición de sus especies. El intradomicilio obtuvo las mayores abundancias de mosquitos, sin embargo, su diversidad y equitatividad fue baja a diferencia del peridomicilio, presentándose una disimilitud ligeramente alta entre sus especies. Los resultados obtenidos tienen importancia para el establecimiento de programas de vigilancia y control en los municipios fronterizos en el estado de Chiapas, ya que brindan información base de la presencia y distribución de la fauna de mosquitos.

Abstract Mosquito collection was conducted intradomiciliary and peridomiciliary along the Chiapas-Guatemala international border during October-November 2018. We collected 4,439 specimens belonging to 2 subfamilies, 18 genera and 41 species, one of which Mansonia dyari (Belkin, and Page, 1970) is a new record for Chiapas, and 21 species with medical importance were found. Culex quinquefasciatus and Aedes aegypti were the most common species. Some municipalities with the highest number of species and individuals were not the most diverse and equitable, with a high dissimilarity in species composition. The intradomiciliary collections obtained the highest abundances of species, however the diversity and evenness were low in contrast with the peridomiciliary collections, where obtained slightly high dissimilarity among species. The results obtained have importance for the establishment of surveillance and mosquito control programs in the state of Chiapas, since they provide basic information on the occurrence and distribution of mosquito fauna.

https://doi.org/10.22201/ib.20078706e.2023.94.4063

13.

DIFFUSION STUDY OF NaCl AND KCl AT THE SOLUTION/OLIVE INTERFACE: MATHEMATICAL MODELING USING THE FINITE ELEMENT METHOD AND SELF-ORGANIZING FEATURE MAP (SOFM)-TYPE NEURAL NETWORKS
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Borsato, Dionisio

; Clemente, Marco A. J.

; Silva, Heloisa H. P.

; Silva, Nathan F.

; Campos, Julia W.

; Sousa, Eduardo G. de

; Silva, Hágata C.

; Angilelli, Karina B.

; Mantovani, Ana C. G.

; Mantovani, Rafael G.

Química Nova

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2023, Volumen 46 Nº 8 Paginas 785 - 790

Resumen: En | Texto: En | PDF: En

Olive samples were subjected to the salting process in brine containing 1196 mol m−3 of NaCl and 402 mol m−3 of KCl. Samples were collected during 60 h and salt concentration values were determined. With the finite element method (FEM) and the minimization of the errors percentage between the simulated and experimental values, the mass transfer coefficients in the film (hm) were obtained, being 1.0072 × 10−8 and 1.2499 × 10−8 for NaCl and KCl, respectively. The salts concentration at the olive/brine interface was simulated by FEM and analyzed via SOFM. A network with 4 × 4 topology and 10000 training epochs was used. It was observed that the influence of the stationary film formed on the surface of the olives during the salting process depends on the position, the salt involved in the diffusion and that the concentration of the salts, at each point, varies according to the immersion time.

https://doi.org/10.21577/0100-4042.20230053

14.

Use of Ozonized Water in the Prevention of Surgical Site Infection in Children Undergoing Cardiovascular Surgery
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Murakami, Alexandre Noboru

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Murakami, Rouse Mary Rossini

; Almeida, Margarete Teresa Gottardo de

; Policarpo, Rafael da Silva

; Avona, Fabiana Nakamura

; Godoy, Moacir Fernandes de

Brazilian Journal of Cardiovascular Surgery

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2023, Volumen 38 Nº 6 elocation e20230006

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ABSTRACT Introduction: Since the reduction of healthcare-associated infections has been a focus for quality patient care, this study aimed to evaluate the surgical site infection rate of children who underwent cardiovascular surgery after implementation of ozonized water system for hand and body hygiene allied to previously implemented preventive measures. Methods: Two uniformly comparable groups of pediatric patients underwent cardiovascular surgery. Group A (187) patients were operated prior to installation of ozonized water system (March 1 to August 31, 2019), and group B (214) patients were operated after installation of ozonized water system (October 1, 2019, to March 31, 2020). Ozonized water was used for professional hand hygiene and patient body hygiene. Results: There was statistical significance for surgical site infection reduction in group B (P=0.0289), with a relative risk of 0.560 (95% confidence interval = 0.298 to 0.920), inferring the risk of being diagnosed with surgical site infections in group B was 44% less than in group A. There was no statistical significance regarding mechanical ventilation time (P=0.1998) or mortality (P=0.4457). Conclusion: Ozonized water for professional hand hygiene and patient body hygiene was an adjuvant combined with traditional preventive methods to reduce the risk of surgical site infection, although no impact on hospital stay or mortality was observed.

https://doi.org/10.21470/1678-9741-2023-0006

15.

Model Membranes and Antimicrobial Activities of pH-Sensitive Copolymers
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Saraiva, Greice K.

; Souza, Valdomiro V. de

; Oliveira, Luciana C. de

; Procópio, Alyne

; Martins, Maisa T.

; Aidar, Isabel N.

; Yi, Ronaldo C. F.

; Lacerda, Caroline D.

; Carretero, Gustavo P B.

; Lira, Rafael B. de

; Riske, Karin A.

; Salinas, Roberto K.

; Chaimovich, Hernan

; Florenzano, Fábio H.

; Cuccovia, Iolanda M.

Journal of the Brazilian Chemical Society

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2023, Volumen 34 Nº 12 Paginas 1863 - 1876

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Polymers are options as antimicrobials for skin protection, antifouling surfaces, and fabrics. Here we analyzed the interaction of polymers based on poly(methacrylate) (PMMA) and poly((dimethylamino ethyl) methacrylate) (PDMAEMA) with model membranes and bacteria. We used the homopolymers PMMA, PDMAEMA, and the diblock copolymer(s) prepared with different PMMAm:PDMAEMAn ratios (m/n). The interactions of PDMAEMA and PMMAm-b-PDMAEMAn with large unilamellar vesicles (LUVs) prepared with phosphatidylcholine and phosphatidylglycerol at different pHs, were analyzed by nuclear magnetic resonance (NMR), dynamic light scattering, and zeta potential. These polymers promoted LUVs leakage of a fluorescent probe (5,6-carboxyfluorescein) localized exclusively in the internal aqueous compartment. Interestingly, all copolymers exhibit a bell-shaped pH dependence for the polymer-induced LUVs leakage. The interaction of the positively charged polymers and the pH effect was also demonstrated using giant unilamellar vesicles. These copolymers inhibited bacterial growth in the micromolar range and can be used to prevent bacterial growth on surfaces.

https://doi.org/10.21577/0103-5053.20230079

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