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Abstract The Anais Brasileiros de Dermatologia, published since 1925, is the most influential dermatological journal in Latin America, indexed in the main international bibliographic databases, and occupies the 50th position among the 70 dermatological journals indexed in the Journal of Citations Reports, in 2022. In this article, the authors present a critical analysis of its trajectory in the last decade and compare its main bibliometric indices with Brazilian medical and international dermatological journals. The journal showed consistent growth in different bibliometric indices, which indicates a successful editorial policy and greater visibility in the international scientific community, attracting foreign authors. The increases in citations received (4.1 ×) and in the Article Influence Score (2.9×) were more prominent than those of the main Brazilian medical and international dermatological journals. The success of Anais Brasileiros de Dermatologia in the international scientific scenario depends on an assertive editorial policy, on promptly publication of high-quality articles, and on institutional stimulus to encourage clinical research in dermatology.

https://doi.org/10.1016/j.abd.2023.08.003

Brown spiders (Loxosceles) are taking hold in Pernambuco, Brazil: a case series, 2018-2022
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Amorim, Maria Lucineide Porto

; Simão, Diógenes Gayo de Oliveira

; Albuquerque, João Paulo Vieira e Silva de

; Ramos, Beatriz Maria Tenório

; Nascimento, Gustavo José Lopes do

; Mello, Maria Júlia Gonçalves de

Epidemiologia e Serviços de Saúde

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2024, Volumen 33 elocation e2023568

Resumen: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective To describe accidents involving brown spider (genus Loxosceles) bites notified by the Pernambuco Poison Information and Care Center (CIATox-PE), Brazil, from January 2018 to December 2022. Methods This was a case series study of brown spider bites notified by the CIATox-PE. Results The study included 22 cases with median age of 35 years, the majority being female (13); the cases occurred in rural and urban areas (12 versus 10), at night (10); Petrolina was the municipality with the highest number of notifications (6); spider bites occurred mainly in the lower (11) and upper (9) limbs, almost exclusively inside households (21); specific serum therapy was not indicated for 8 cases because the time for its effectiveness had already elapsed. Conclusion Loxoscelism cases occurred more frequently in females, in both rural and urban areas and mainly at home, with delays in seeking medical care.

RESUMEN Objetivo Describir accidentes causados por arañas pardas (género Loxosceles) notificados por el Centro de Información de Asistencia Toxicológica de Pernambuco (CIATox-PE), Brasil, de enero de 2018 a diciembre de 2022. Métodos Reporte de 22 casos notificados de CIATox-PE. Resultados Casos con media de idade de 35 años, predominio femenino (13); los casos ocurrieron en área rural/urbana (12 versus 10), por la noche (10); Petrolina fue el municipio con más notificaciones (6); las picaduras fueron principalmente en los miembros inferiores (11) y superiores (9), casi exclusivamente en el interior de las viviendas (21); en 8 de los casos no se indicó sueroterapia específica por haber superado el tiempo de efecto. Conclusión Los casos de loxoscelismo ocurrieron con mayor frecuencia en el sexo femenino, en áreas rurales y urbanas, y principalmente en el hogar, con demoras en la búsqueda de atención médica.

RESUMO Objetivo Descrever os acidentes por picada de aranhas-marrons (gênero Loxosceles), notificados no Centro de Informação de Assistência Toxicológica de Pernambuco (CIATox-PE), Brasil, no período de 2018 a 2022. Métodos Estudo de série, sobre casos notificados no CIATox-PE. Resultados Foram incluídos 22 casos com mediana de idade de 35 anos e houve predomínio do sexo feminino (13); os casos ocorreram nas zonas rural e urbana (12 versus 10), durante a noite (10), e Petrolina foi o município com mais notificações (6); as picadas ocorreram, principalmente, nos membros inferiores (11) e superiores (9), quase exclusivamente dentro das residências (21); para 8 acidentados, não se prescreveu soroterapia específica por terem ultrapassado o tempo de efetividade. Conclusão Os casos de loxoscelismo ocorreram com maior frequência no sexo feminino, nas zonas rural e urbana indiferentemente, quase todos foram intradomiciliares e houve demora na procura por atendimento médico.

https://doi.org/10.1590/s2237-96222024v33e2023568.en

Prevalence and antimicrobial resistance profile of pathogens isolated from patients with urine tract infections admitted to a university hospital in a medium-sized Brazilian city
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Negri, Mariana

; Lima, Bárbara Martins

; Woloszynek, Renata dos Santos Batista Reis

; Molina, Roberto Augusto Silva

; Germano, Carla Maria Ramos

; Melo, Débora Gusmão

; Souza, Leandro Cândido de

; Avó, Lucimar Retto da Silva de

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volumen 66 elocation e3

Resumen: En | Texto: En | PDF: En

ABSTRACT This study aimed to determine the antibiotic profile of microorganisms isolated from urine samples of patients with community urine tract infections (UTI) admitted to the University Hospital of the Federal University of Sao Carlos to support an appropriate local empirical treatment. A retrospective cross-sectional study was conducted from October 2018 to October 2020. Data from 1,528 positive urine cultures for bacterial pathogens and antibiograms were tabulated. Bacterial species prevalence and their resistance profile were analyzed and compared by sex and age. For Gram-negative fermenting bacteria, resistance rates were compared between patients with previous hospitalization and the total of infections caused by this group. For comparisons, the Chi-square test was performed, using Fisher’s exact test when necessary (BioEstat program, adopting p ≤ 0.05). A multivariate analysis was applied to assess the effect of the studied variables in predicting multidrug resistance. Infections were more prevalent in women and older adults. Gram-negative bacteria represented 90.44% of total cultures. In both sexes, E. coli prevalence was significantly higher in adults compared with older adults (p < 0.0001). For several antibiotics, resistance rates were higher in the older adults compared with other ages and in patients with Gram-negative fermenting infections and previous hospitalization compared with the total of infections by this group of bacteria. The closer to the hospitalization, the higher the number of antibiotics with superior resistance rates. Resistance rates for aminoglycosides, carbapenems, ceftazidime, nitrofurantoin, piperacillin+tazobactam, and fosfomycin were less than 20%, considered adequate for empirical treatment. Only hospitalization in the previous 90 days was statistically significant in predicting infections by multidrug-resistant bacteria.

https://doi.org/10.1590/s1678-9946202466003

Brown spiders (Loxosceles) are taking hold in Pernambuco, Brazil: a case series, 2018-2022
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Amorim, Maria Lucineide Porto

; Simão, Diógenes Gayo de Oliveira

; Albuquerque, João Paulo Vieira e Silva de

; Ramos, Beatriz Maria Tenório

; Nascimento, Gustavo José Lopes do

; Mello, Maria Júlia Gonçalves de

Epidemiologia e Serviços de Saúde

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2024, Volumen 33 elocation e2023568

Resumen: Pt Es En | Texto: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/s2237-96222024v33e2023568.en

Enhancing understanding of SARS-CoV-2 infection among individuals with Down syndrome: An integrative review
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Silva, Maria Vitoria Gomes da

; Pereira, Laura Resende Guimarães

; Avó, Lucimar Retto da Silva de

; Germano, Carla Maria Ramos

; Melo, Débora Gusmão

Sao Paulo Medical Journal

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2024, Volumen 142 Nº 2 elocation e2023015

Resumen: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Down syndrome (DS) is a non-rare genetic condition that affects approximately 1 in every 800 live births worldwide. Further, it is associated with comorbidities, anatomical alterations of the respiratory tract, and immunological dysfunctions that make individuals more susceptible to respiratory infections. OBJECTIVE: To systematize the current scientific knowledge about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among individuals with DS. DESIGN AND SETTING: This integrative review was conducted at the Universidade Federal de São Carlos, São Paulo, Brazil. METHODS: This review was conducted in the following databases: the Virtual Health Library (Biblioteca Virtual em Saúde, BVS), PubMed, and Web of Science, using MeSH descriptors. The search included English or Portuguese studies published between January 1, 2020, and October 14, 2022. RESULTS: A total of 55 articles from 24 countries were selected, comprising 21 case-control or cohort studies, 23 case reports or series, and 11 narrative reviews or opinion studies. The articles were grouped into five categories: previous comorbidities, coronavirus disease 2019 (COVID-19) clinical features and evolution, cytokine storm and interleukins, living in institutions as a risk factor, and behavioral actions as a protective factor against SARS-CoV-2 infection. CONCLUSION: Individuals with DS are more susceptible to COVID-19 infection due to variables such as previous comorbidities, immunological factors, and their habitable environments. These aspects confer a higher risk of infection and an unfavorable clinical course. The precise pathways involved in the pathophysiology of COVID-19 in individuals with DS are not clear, thus requiring further studies. SYSTEMATIC REVIEW REGISTRATION: The Open Science Framework registered the research protocol (https://osf.io/jyb97/).

https://doi.org/10.1590/1516-3180.2023.0015.r1.230523

Multidimensionality of agricultural grain road freight price: a multiple linear regression model approach by variable selection
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Macarringue, Alcília Mena José Sitoe

; Oliveira, Andréa Leda Ramos de

; Dias, Carlos Tadeu dos Santos

; Marsola, Karina Braga

Ciência Rural

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2024, Volumen 54 Nº 4 elocation e20220335

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT: The road system is the main mode used for the transportation of agricultural cargo, and in some cases, it is the only option for handling this type of product. This dependence means that the implementation of tools to support the management of logistical costs can reduce the financial impact with the transport felt by the economic agents operating in the soybean chain. This study contributed to a better understanding of the variables that make up the cost of road freight, generating a system of road freight prediction from a multiple linear regression model using the selection of variables Stepwise, Forward, and Backward elimination. This being said, this research intends to evaluate whether the behavior of soybean road freight is influenced by the variables that make up the productive, economic, and infrastructure dimensions in price formation. The regression models had an explanatory power of 87.20%. In the infrastructure dimension, the most impact variable in soybean road freight was the distance traveled; in the economic dimension, the variables of inflation and fuel price stood out; while in the productive dimension, the main contribution was the volume of production. A more assertive predictability of logistical costs and better understanding of the dynamics of freight price formation helps industry agents in planning and decision-making. Another contribution of this study is that it can be used as a practical tool for predicting soybean road freight on several transportation routes.

RESUMO: O sistema rodoviário é o principal modal utilizado para o transporte de cargas agrícolas, e em alguns casos, é a única opção para movimentação desse tipo de produto. Esta dependência faz com que a implementação de ferramentas para apoiar a gestão dos custos logísticos possa reduzir o impacto financeiro com o transporte sentido pelos agentes econômicos que atuam na cadeia da soja. O presente trabalho visa contribuir para um melhor entendimento das variáveis que compõem o custo dos fretes rodoviários, gerando um sistema de previsão de fretes rodoviários a partir de um modelo de regressão linear múltipla usando a seleção de variáveis Stepwise, Forward e a eliminação Backward. Isto posto, a pesquisa tem por objetivo avaliar se o comportamento do frete rodoviário da soja é influenciado pelas variáveis que compõem as dimensões produtivas, econômicas e de infraestrutura na formação do preço. Os modelos de regressão tiveram um poder explicativo de 87,20%. Na dimensão infraestrutura o destaque foi a variável distância percorrida como a mais impactante no frete rodoviário da soja, na dimensão econômica as variáveis inflação e preço do combustível, enquanto que na dimensão produtiva a principal contribuição foi o volume de produção. A previsibilidade mais assertiva dos custos logísticos e melhor compreensão da dinâmica de formação do preço do frete auxilia os agentes do setor no planejamento e na tomada de decisão. Outra contribuição deste trabalho é que pode ser usado como uma ferramenta prática para a predição de fretes rodoviários da soja em diversas rotas de transporte.

https://doi.org/10.1590/0103-8478cr20220335

[SciELO Preprints] - CD114 MEMBRANE RECEPTORS CAN HELP IN THE ASSESSMENT OF MOLECULAR MORTALITY IN MEDULOBLASTOMAS?
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Monteiro, Jander Moreira Ramos , Jaqueline Isadora Reis Sousa, Ian Teixeira e Bighetti-Trevisan, Rayana Longo Ribas-Filho, Jurandir Marcondes Isolan, Gustavo Rassier Nassif , Paulo Afonso Nunes Polanski , José Fernando

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Fecha de publicación: 2023-12-15

Resumen: En Pt

Introduction: Medulloblastomas are the most common solid tumors of childhood and many studies seek to develop new chemotherapy drugs by identifying genes whose expression is new molecular targets for drugs, such as membrane receptors associated with cell replication. Objective: To review existing knowledge about the association of CD114 expression with mortality in medulloblastoma. Method: Narrative review collecting information with material for reading and analysis selected from research on virtual platforms (SciELO, Pubmed and Scopus). Initially, a search was carried out for descriptors related to the topic, which were identified through MESH using the following terms: “neurosurgery, surgical oncology, molecular targeted therapy, medulloblastoma” with AND or OR search, considering the title and/or abstract. After, the search was carried out, the title and abstract were analyzed and those that could be included were read in full. Results: 23 articles were included. Conclusion: There is no direct relationship between the expression of the CD114 membrane receptor and mortality in patients with medulloblastoma, and additional studies should be carried out on the intracellular signaling pathways associated with this receptor and its gene, CSF3R

Introdução: Meduloblastomas são os tumores sólidos mais comuns da infância e muitos estudos buscam desenvolvimento de novos quimioterápicos com a identificação de genes cuja expressão sejam novos alvos moleculares para drogas, como receptores de membrana associados à replicação celular. Objetivo: Revisar o cohecimento existente sobre a associação da expressão de CD114 com a mortalidade no meduloblastoma. Método: Revisão narrativa colhendo informações com o material para leitura e análise selecionado a partir de pesquisa em plataformas virtuais (SciELO, Pubmed e Scopus). Inicialmente foi realizada busca por descritores relacionados ao tema, os quais foram identificados por meio do DeCS utilizando os seguintes termos: “neurocirurgia, oncologia cirúrgica, terapia de alvo molecular, meduloblastoma” ” e seus equivalentes em inglês  “neurosurgery, surgical oncology, molecular targeted therapy, medulloblastoma” com busca AND ou OR, considerando o título e/ou resumo. Feita a busca, foi realizada análise do título, resumo e lidos na íntegra aqueles que poderiam ser incluídos.  Resultados: Foram incluídos 23 artigos. Conclusão: Não há relação direta entre a expressão do receptor de membrana CD114 e a mortalidade em pacientes portadores de meduloblastoma e estudos adicionais devem ser feitos sobre as vias de sinalização intracelulares associadas a esse receptor e ao seu gene, o CSF3R.

https://doi.org/10.1590/SciELOPreprints.7717

Aplicação da Medication Fall Risk Score em doentes com notificação de incidente de queda: Análise retrospetiva
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Souza, Luciana Marques de

; Ramos, Susana Maria Sardinha Vieira

; Isoppo, Catherine Stragliotto

; Diniz, Ana Marinho

; Ferreira, Catarina Isabel Gomes Mendes

; Sousa, Paulo

Revista de Enfermagem Referência

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Dic 2023, Volumen serVI Nº 2 elocation e22087

Resumen: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

Abstract Background: Falls in hospital settings are frequent adverse events, with medications contributing significantly. Objective: To analyze inpatient fall notifications and characterize fall risk with a focus on drug therapy by applying the Medication Fall Risk Score. Methodology: An observational, descriptive, and retrospective study was conducted in a Portuguese hospital center. The Medication Fall Risk Score was applied to a sample of 183 patient fall notifications in the first quarter of 2021. Results: The Medication Fall Risk Score identified 60.6% of patients with "yes" for high fall risk. Regarding fall risk assessment recorded in the notifications using another scale, 65.8% of patients were classified as "low risk" or "no risk." Of these, 53.9% were classified as "yes" for high risk using the Medication Fall Risk Score. Conclusion: The Medication Fall Risk Score may help to improve the detection of patients at "high risk" of falling, allowing safer medication practices for fall prevention.

Resumo Enquadramento: As quedas em contexto hospitalar são eventos adversos frequentes, sendo os medicamentos um importante fator contribuinte. Objetivo: Analisar notificações de queda de doentes internados e caracterizar o risco de queda com foco na terapia farmacológica, através da aplicação da Medication Fall Risk Score. Metodologia: Estudo observacional, descritivo e retrospetivo realizado num centro hospitalar português. Aplicada a Medication Fall Risk Score, numa amostra de 183 notificações de queda ocorridas no primeiro trimestre de 2021. Resultados: A Medication Fall Risk Score identificou 60,6% dos doentes com “sim” para o alto risco de queda. Relativamente à avaliação de risco de queda registada nas notificações com recurso a outra escala, identificou-se que 65,8% dos doentes foram classificados como "baixo risco" ou "sem risco". Desses, 53,9% foram classificados com "sim” para o alto risco através da Medication Fall Risk Score. Conclusão: A Medication Fall Risk Score poderá contribuir para melhorar a deteção de doentes com “alto risco” de queda, permitindo uma gestão mais segura dos medicamentos para a prevenção das quedas.

Resumen Marco contextual: Las caídas en los hospitales son eventos adversos frecuentes y la medicación es un factor importante. Objetivo: Analizar las notificaciones de caída de pacientes hospitalizados y caracterizar el riesgo de caída centrándose en el tratamiento farmacológico, mediante la aplicación de la Medication Fall Risk Score. Metodología: Estudio observacional, descriptivo y retrospectivo realizado en un centro hospitalario portugués. Aplicada la Medication Fall Risk Score en una muestra de 183 notificaciones de caída ocurridas en el primer trimestre de 2021. Resultados: La Medication Fall Risk Score identificó al 60,6% de los pacientes con un "sí" para riesgo de caída elevado. En cuanto a la evaluación del riesgo de caída registrada en las notificaciones mediante otra escala, el 65,8% de los pacientes fueron clasificados como de “riesgo bajo" o "sin riesgo". De ellos, el 53,9% se clasificaron con un "sí" para riesgo elevado a través de la Medication Fall Risk Score. Conclusión: La Medication Fall Risk Score podría ayudar a mejorar la detección de pacientes con “riesgo elevado" de caída, lo que permitiría una gestión más segura de los medicamentos para prevenirla.

https://doi.org/10.12707/rvi22087

Brazilian dental consensus on dental management in hematopoietic stem cell transplantation−Part I−pre-HSCT
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Correa, Maria Elvira Pizzigati

; Granzotto, Fabiana Caramori Noal

; Innocentini, Lara Maria Alencar Ramos

; Reis, Thiago de Carvalho

; Lima, Emilze Mafra de

; Varanda, Renata de Freitas

; Santos, Paulo Sérgio da Silva

; Soares Junior, Luiz Alberto Valente

; Bezinelli, Leticia Mello

; Eduardo, Fernanda de Paula

; Melo, Walmyr Ribeiro

; Antunes, Héliton Spíndola

; Macedo, Leandro Dorigan De

Hematology, Transfusion and Cell Therapy

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Sep 2023, Volumen 45 Nº 3 Paginas 358 - 367

Resumen: En | Texto: En | PDF: En

ABSTRACT The oral involvement in the Hematopoietic Stem Cell Transplantation is well described in the literature. The goal of the dental treatment and management of the oral lesions related to the HSCT is to reduce the harm caused by preexisting oral infection or even the worsening of oral acute/chronic GVHD and late effects. The aim of this guideline was to discuss the dental management of patients subjected to HSCT, considering three phases of the HSCT: pre-HSCT, acute phase, and late phase. The literature published from 2010 to 2020 was reviewed in order to identify dental interventions in this patient population. The selected papers were divided into three groups: pre-HSCT, acute and late, and were reviewed by the SBTMO Dental Committee's members. When necessary, an expertise opinion was considered for better translating the guideline recommendations to our population dental characteristics. This manuscript focused on the pre-HSCT dental management. The objective of the pre-HSCT dental management is to identify possible dental situations that On behalf of the Dental Committee of the Brazilian Society of Gene Therapy and Bone Marrow Transplantation (SBTMO) can worsening during the acute phase after the HSCT. Each guideline recommendations were made considering the Dentistry Specialties. The clinical consensus on dental management prior to HSCT provides professional health caregivers with clinical setting-specific information to help with the management of dental problems in patients to be subjected to HSCT.

https://doi.org/10.1016/j.htct.2023.04.001

10.

Physical rehabilitation in Brazilian pediatric intensive care units: a multicenter point prevalence study
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Redivo, Juliana

; Kannan, Harini

; Souza, Andreia Aparecida Freitas

; Colleti Junior, José

; Kudchadkar, Sapna Ravi

; Horigoshi, Nelson Kazunobu

; Costa, Graziela de Araújo

; Castilho, Taísa Roberta Ramos de

; Peron, Paula Peres Domingues

; Scaranto, Walter Perez

; Medeiros, Daniela Nasu Monteiro

; Matsumoto, Toshio

; Almeida, Carlos Gustavo de

; Oliveira, Felipe Rezende Caino de

; Brandão, Marcelo Barciela

; Lima-Setta, Fernanda

; Prata-Barbosa, Arnaldo

; Xavier, Glaciele Nascimento

; Andrade, Livia Barbosa de

; Aguiar, Agda Ultra de

; Coutinho, Marcos Paulo Galdino

; Castro, Roberta Esteves Viera de

; Landy, Glazia André

; Balaniuc, Suzana Lopes Bonfim

; Yamaguchi, Ricardo Silveira

Critical Care Science

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Sep 2023, Volumen 35 Nº 3 Paginas 290 - 301

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To determine the prevalence and factors associated with the physical rehabilitation of critically ill children in Brazilian pediatric intensive care units. Methods: A 2-day, cross-sectional, multicenter point prevalence study comprising 27 pediatric intensive care units (out of 738) was conducted in Brazil in April and June 2019. This Brazilian study was part of a large multinational study called Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). The primary outcome was the prevalence of mobility provided by physical therapy or occupational therapy. Clinical data on patient mobility, potential mobility safety events, and mobilization barriers were prospectively collected in patients admitted for ≥ 72 hours. Results: Children under the age of 3 years comprised 68% of the patient population. The prevalence of therapist-provided mobility was 74%, or 277 out of the 375 patient-days. Out-of-bed mobility was most positively associated with family presence (adjusted odds ratios 3.31;95%CI 1.70 - 6.43) and most negatively associated with arterial lines (adjusted odds ratios 0.16; 95%CI 0.05 - 0.57). Barriers to mobilization were reported on 27% of patient-days, the most common being lack of physician order (n = 18). Potential safety events occurred in 3% of all mobilization events. Conclusion: Therapist-provided mobility in Brazilian pediatric intensive care units is frequent. Family presence was high and positively associated with out-of-bed mobility. The presence of physiotherapists 24 hours a day in Brazilian pediatric intensive care units may have a substantial impact on the mobilization of critically ill children.

RESUMO Objetivo: Determinar a prevalência e os fatores associados à reabilitação física de crianças em estado grave em unidades de terapia intensiva pediátrica brasileiras. Métodos: Realizou-se um estudo de prevalência pontual multicêntrico, transversal, de 2 dias, abrangendo 27 unidades de terapia intensiva pediátrica (do total de 738) no Brasil em abril e junho de 2019. Este estudo brasileiro fez parte de um grande estudo multinacional chamado Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). O desfecho primário foi a prevalência de mobilidade proporcionada pela fisioterapia ou pela terapia ocupacional. Foram coletados prospectivamente dados clínicos sobre a mobilidade do paciente, possíveis eventos de segurança de mobilidade e barreiras de mobilização em pacientes admitidos por ≥ 72 horas. Resultados: As crianças com idade inferior a 3 anos eram 68% da população de pacientes. A prevalência de mobilidade fornecida pelo terapeuta foi de 74%, ou 277 dos 375 pacientes-dia. A mobilidade para fora do leito foi mais positivamente associada à presença de familiares (razão de chance ajustada de 3,31; IC95% 1,70 - 6,43) e mais negativamente associada às linhas arteriais (razão de chance ajustada de 0,16; IC95% 0,05 - 0,57). Foram relatadas barreiras à mobilização em 27% dos pacientes-dia, sendo a mais comum a falta de prescrição médica (n = 18). Registaram-se eventuais eventos de segurança em 3% de todos os eventos de mobilização. Conclusão: A mobilidade proporcionada pelo terapeuta nas unidades de terapia intensiva pediátrica brasileiras é frequente. A presença de familiares foi alta e positivamente associada à mobilidade para fora do leito. A presença de fisioterapeutas 24 horas por dia nas unidades de terapia intensiva pediátrica brasileiras pode exercer papel importante na mobilização de crianças em estado grave.

https://doi.org/10.5935/2965-2774.20230388-en

11.

Cristianismo libertário e redenção em Roberto Rossellini e Pier Paolo Pasolini
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RAMOS, PAULO ROBERTO

Estudos Avançados

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Ago 2023, Volumen 37 Nº 108 Paginas 261 - 276

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT This article attempts to link literature and cinema through the concept of resistance, developed by Alfredo Bosi in the literary field, as a form of opposition to any type of violence and exploitation. For Bosi, this ethical concept is the unbreakable link that unites a writer to his or her historical moment. In Stromboli land of God (1949-50) and Francis, God’s Jester (1950), Rossellini turns to the sacred to reaffirm the forces of life in a world that had just emerged from the Second World War. In his film adaptation of the Gospel according to Saint Matthew (1964), Pier Paolo Pasolini uses the Scriptures as an instrument of opposition to a form of capitalism based only on technique, on utilitarian thinking and on increasingly exacerbated forms of consumption.

RESUMO Este artigo intenta realizar uma articulação entre a literatura e o cinema através do conceito desenvolvido por Alfredo Bosi no campo literário da resistência como forma de oposição a qualquer tipo de violência e exploração. Para o pensador brasileiro, esse conceito ético é o elo inquebrantável que une o escritor ao seu momento histórico. Em Stromboli terra de Deus (Stromboli terra di Dio, 1949-50) e Francisco arauto de Deus (Francesco giullare di Dio, 1950) Roberto Rossellini se volta para o sagrado para reafirmar as forças da vida num mundo que acabara de sair da Segunda Guerra Mundial. Em sua adaptação para o cinema do Evangelho segundo São Mateus (Il Vangelo Secondo Matteo, 1964) Pier Paolo Pasolini se serve do texto das escrituras como instrumento de oposição ao frio capitalismo da técnica, do pensamento utilitário e das formas cada vez mais exacerbadas de consumo.

https://doi.org/10.1590/s0103-4014.2023.37108.016

12.

Female-pattern hair loss: therapeutic update
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Ramos, Paulo Müller

; Melo, Daniel Fernandes

; Radwanski, Henrique

; Almeida, Rita Fernanda Cortez de

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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Ago 2023, Volumen 98 Nº 4 Paginas 506 - 519

Resumen: En | Texto: En | PDF: En

Abstract Female androgenetic alopecia or female-pattern hair loss (FPHL) is highly prevalent and has a great impact on the quality of life. The treatment is a routine challenge in dermatological practice, as many therapeutic options have a limited level of evidence and often do not meet patients expectations. Lack of knowledge of the pathogenesis of the hair miniaturization process and the factors that regulate follicular morphogenesis restricts the prospect of innovative therapies. There is also a lack of randomized, controlled studies with longitudinal follow-up, using objective outcomes and exploring the performance of the available treatments and their combinations. Topical minoxidil, which has been used to treat female pattern hair loss since the 1990s, is the only medication that has a high level of evidence and remains the first choice. However, about 40% of patients do not show improvement with this treatment. In this article, the authors critically discuss the main clinical and surgical therapeutic alternatives for FPHL, as well as present camouflage methods that can be used in more extensive or unresponsive cases.

https://doi.org/10.1016/j.abd.2022.09.006

13.

Case for diagnosis. Cicatricial alopecia on the vertex -Folliculitis decalvans and lichen planopilaris phenotypic spectrum diagnosis Folliculitis
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Miola, Anna Carolina

; Ramos, Paulo Muller

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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Ago 2023, Volumen 98 Nº 4 Paginas 533 - 536

Resumen: En | Texto: En | PDF: En

https://doi.org/10.1016/j.abd.2021.11.013

14.

In vivo elicitation is efficient in increasing essential oil yield with high anti-inflammatory sesquiterpene content in Varronia curassavica Jacq.
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Ramos Melo, Elisa

; Gomes Fabri, Eliane

; Magalhães, Hélida Mara

; Gorni, Pedro Henrique

; Pacheco, Ana Cláudia

Chilean journal of agricultural research

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Jun 2023, Volumen 83 Nº 3 Paginas 369 - 379

Resumen: En | Texto: En | PDF: En

ABSTRACT Essential oils in plants are produced in very low concentrations and elicitation stands out among the techniques used to increase their productivity. This work evaluated the potential elicitor of salicylic acid (SA) or seaweed extract (SE) on the biomass yield, physiological parameters and essential oil production in Varronia curassavica Jacq. plants. The elicitors were applied through foliar spray in four serial applications (21, 34, 53 and 70 d after transplanting the seedlings to the pots - DAT), in concentrations of 1 mM (SA) and 5 mL L-1 (SE). The control plants were sprayed with water. Biometric measurements of plant height and number of branches were performed after 2, 3 and 4 elicitor applications. Plants were harvested at 91 DAT and biometric, biochemical and phytochemical parameters were evaluated. Application of SA resulted in increases in number of leaves (11.68%) and foliar concentrations of chlorophylls (57.67%), anthocyanins (73.80%), carotenoids (42.58%), total soluble sugars (19.48%) and essential oil (18%). The plants treated with SE had no changes in leaf biomass or essential oil production. The SA treatment increased by twice the amount of α-humulene and (E)-caryophyllene present in the essential oil while for SE treatment there was an average increase of 78.6%. It was concluded that the elicitation of V. curassavica plants by SA foliar pulverization is an efficient strategy for promoting the higher productivity of leaves and essential oil. Foliar pulverization of SA or SE modifies essential oil quality, inducing increases in the compounds of greatest interest for the pharmaceutical industry.

15.

Biomechanical Behavior Evaluation of a Mandibular Full-Arch Implant-Supported Prosthesis on ZrO2 and TiO2 Monotype Dental Implants
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Melo de Matos, Jefferson David

; de Carvalho Ramos, Nathália

; Queiroz, Daher Antonio

; Coelho Sinhoreti, Mário Alexandre

; Baldotto Barbosa, Adriano

; Bottino, Marco Antonio

; Souto Borges, Alexandre Luiz

; da Rocha Scalzer Lopes, Guilherme

International journal of odontostomatology

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Jun 2023, Volumen 17 Nº 2 Paginas 174 - 185

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT: This in silico study aimed to evaluate the biomechanical behavior of a full-arch implant-supported prosthesis on titanium and zirconia monotype implants. A 3D mandible containing 1.0 mm thick cortical and cancellous bone was modeled. Four dental implants (3.3 x 10 mm) were inserted into the jaw model in each model. The implants consisted of Titanium (Ti-S group) and Zirconia Monotype/one-piece (Zr-S group). Fixed full-arch implant-supported prostheses were cemented onto the implant. The models were exported to the analysis software and divided into meshes composed of nodes and tetrahedral elements. All materials were considered isotropic, elastic, and homogeneous. Therefore, all contacts were considered bonded, the mandible model was fixed in all directions, applying a static structural axial load of 300 N on the bottom of the fossa of the left mola r teeth. Microstrain and von-Mises stress (MPa) were adopted as failure criteria. Comparable stress and strain values were shown in the peri-implant bone for both groups. However, the Ti-S group presented a lower stress value (1,155.8 MPa) than the Zr-S group (1,334.2 MPa). Regarding bone tissues, the Ti-S group presented 612 µε and the Zr-S group presented 254 µε. The highest strain peak was observed in bone tissues around the implant closer to the load for both groups. Evaluating monotype zirconia and titanium implants, it is suggested that the greater the rigidity of the implant, the greater the concentration of internal stre sses and the less dissipation to the surrounding tissues. Therefore, monotype ceramic implants composed of yttrium-stabilized tetragonal polycrystalline zirconia may be a viable alternative to titanium implants for full-arch prostheses.

RESUMEN: El objetivo de este estudio in silico fue evaluar el comportamiento biomecánico de una prótesis implanto soportada de arcada completa sobre implantes monotipo de titanio y zirconia. Se modeló una mandíbula en 3D que contenía tejido óseo cortical y esponjoso de 1,0 mm de espesor. En cada modelo, se insertaron cuatro implantes dentales (3,3 x 10 mm) en el modelo de mandíbula. Los implantes consistieron en Monotipo de Titanio y Zirconia. Sobre el implante se cementaron prótesis implanto soportadas de arcada completa fija. Los modelos se exportaron al software de análisis y se dividieron en mallas compuestas por nodos y elementos tetraédricos. Todos los materiales se consideraron isotrópicos, elásticos y homogéneos. Por lo tanto, todos los contactos se consideraron cementados, el modelo mandibular se fijó en todas las direcciones, aplicando una carga vertical estructural estática de 300 N en el fondo de la fosa de los dientes molares izquierdos. Se seleccionaron la microesfuerzo y la tensión de Von-Mises (MPa) como criterios de falla. Se mostraron valores de tensión y deformación comparables en el hueso periimplantario para ambos grupos. Sin embargo, el grupo Ti-S presentó un valor de estrés menor (1.155,8 MPa) que el grupo Zr-S (1.334,2 MPa). En cuanto a los tejidos óseos, el grupo Ti-S presentó 612 µε y el grupo Zr-S presentó 254 µε. La mayor concentración de deformación en el tejido óseo se observó en los tejidos alrededor del implante más cerca de la carga para ambos grupos. Al evaluar los implantes monotípicos de zirconia y titanio, se sugiere que cuanto mayor sea la rigidez del implante, mayor será la concentración de tensiones internas y menor la disipación a los tejidos circundantes. Por lo tanto, los implantes cerámicos monotipo compuestos de zirconia policristalina tetragonal estabilizada con itrio pueden ser una alternativa viable a los implantes de titanio para prótesis de arcada completa.

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