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ABSTRACT Introduction: The Band 3 is a red blood cell protein that carries the Dia and Dib antigens from the Diego blood system. The SLC4A1 gene encodes Band 3; Band 3 Memphis is a polymorphism of normal Band 3 and has two variants, but only the variant II carries the Dia antigen. Objectives: Describe the frequencies of the DI*A and DI*B alleles and the Band 3 Memphis among blood donors, sickle cell disease (SCD) patients and Amazonian Indians. Methods: A total of 427 blood samples were collected and separated into three groups: 206 unrelated blood donors, 90 patients with SCD and 131 Amazonian Indians. We performed DI*A/B, normal Band 3 and Band 3 Memphis genotyping, using the Polymerase Chain Reaction Restriction Fragment Length Polymorphism (PCR–RFLP). Results: The frequency of the DI*A/DI*A genotype was 0.5% in blood donors and it was not found in other groups. The frequency of the DI*A/DI*B was higher in Amazonian Indians (33.6%) and the frequency of the DI*B/DI*B was highest in blood donors (92.2%). All 105 individuals tested were positive for the presence of normal Band 3 and of these individuals, only 5/105 (4.8%) presented the Band 3 Memphis mutation. Conclusion: We observed a higher frequency of the DI*B allele in blood donors and a low frequency of the DI*A/DI*A genotype in all groups studied. The Band 3 Memphis was found in a higher frequency in the blood donor group. Our findings highlight the importance of analyzing different population groups to gain a better understanding of the genetic association of blood group antigens.

https://doi.org/10.1016/j.htct.2022.03.002

Correlação entre variáveis antropométricas e o desempenho físico em bombeiros guarda vidas
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Mello, Ricardo Castro Ferreira de

; Freitas, Fabio Henrique de

; Souza, Francine Ribeiro de Oliveira

; Souza, Rafaella Alves de Oliveira

; Gonçalves, Michel Moraes

; Sirieiro, Paolo Veiga

; Gomes, Diego Viana

; Miranda, Humberto Lameira

Motricidade

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Jun 2023, Volumen 19 Nº 2 Paginas 198 - 204

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Some scientific evidence shows that military personnel, including lifeguard firefighters, with high levels of physical fitness may be able to perform their work tasks more efficiently and make the best decisions. The present work aimed to investigate the correlation between anthropometric variables and physical performance in lifeguard firefighters. The sample consisted of 105 men, lifeguard firefighters from the military fire department of the state of Rio de Janeiro. On the first visit, the following procedures were performed: a) completion of the par-Q and the Informed Consent Form; b) anthropometric and body composition measurements. On the second visit, the following tests were performed: 1) 20-meter sprint; 2) zigzag COD; 3) Running Anaerobic Sprint Test. Positive correlations were observed between abdominal perimeter and time in the 20-meter sprint, time in the zig-zag COD, total time in the Running Anaerobic Sprint Test; between waist-to-hip ratio and time in the 20-meter sprint, total time in the Running Anaerobic Sprint Test. Furthermore, negative correlations were observed between abdominal perimeter and velocity in the 20-meter sprint, velocity in the zig-zag COD; between waist-to-hip ratio and speed in the 20-meter sprint. However, no correlations were observed between the perimeter of the abdomen and the fatigue index; between waist-to-hip ratio and zig-zag time and speed COD, fatigue index. it was verified that, in lifeguard firefighters, high scores of abdominal circumference and waist-to-hip ratio negatively influence physical performance.

RESUMO Algumas evidências mostram que militares, dentre eles os bombeiros guarda-vidas, com elevados níveis de aptidão física podem ser capazes de executar suas tarefas laborais com maior eficiência e tomar as melhores decisões. O objetivo do presente trabalho foi investigar a correlação entre variáveis antropométricas e desempenho físico, em bombeiros guarda-vidas. A amostra foi composta por 105 homens, bombeiros guarda-vidas do corpo de bombeiros militares do estado do Rio de Janeiro. Foram observadas correlações positivas entre perímetro do abdômen e tempo no sprint de 20 metros, tempo no zig zag COD, tempo total no Running Anaerobic Sprint Test; entre relação cintura quadril e tempo no sprint de 20 metros, tempo total no Running Anaerobic Sprint Test. Além do mais, foram observadas correlações negativas entre perímetro do abdômen e velocidade no sprint de 20 metros, velocidade no zig zag COD; entre relação cintura quadril e velocidade no sprint de 20 metros. Entretanto, não foram observadas correlações entre perímetro do abdômen e índice de fadiga; entre relação cintura quadril e tempo e velocidade no zig zag COD, índice de fadiga. Verifica-se que, em bombeiros guarda-vidas, elevados escores de circunferência abdominal e relação cintura quadril influenciam, de forma negativa, no desempenho físico.

https://doi.org/10.6063/motricidade.29357

Sensory analysis of goat cheese feed with sorghum silage levels in forage cactus based diets
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Sobral, Gilberto de Carvalho

; Oliveira, Juliana Silva de

; Saraiva, Carla Aparecida Soares

; Santos, Edson Mauro

; Vieira, Diego de Sousa

; Cruz, Antoniel Florencio da

; Torres Junior, Paulo da Cunha

; Albuquerque, Ítalo Reneu Rosas de

; Araújo, Alessandra Oliveira de

; Ribeiro, Neila Lidiany

Food Science and Technology

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2023, Volumen 43 elocation e90022

Resumen: En | Texto: En | PDF: En

Abstract: The objective of this study was to evaluate the quality of milk and cheese and sensory analysis of cheese from goats that received a diet with different levels of sorghum silage in the diet. Twenty Anglonubian dairy goats were used, with an average age of 2 years, average live weight of 43.7 kg, distributed in a completely randomized design, with five replications. Moisture (P=0.001), total solids (P=0.001), fat (p=0.001), TDE (P=0.006) and protein (P=0.003) of goat cheese showed a significant difference due to the inclusion of silage from goat cheese. sorghum in the diet. The sensory attributes soft appearance (P<.0001), look (P<.0001), salty taste (P<.0001) and smooth texture (P=0.0430) showed a significant difference depending on the level of sorghum silage added to the diet. of goats. In the PC analysis, it is observed that three main components were needed to represent the variation of 64.84% of the data. PC 1 determined 29% of the data variation and was represented by the attributes with the highest averages: attractive aroma (5.87) and global acceptability (7.74). The inclusion of up to 45% of sorghum silage in the diet of goats increased milk and cheese fat, which favored high scores for the attributes of softness and global acceptance.

https://doi.org/10.1590/fst.90022

Epidemiological indicators of Chagas disease in the metropolitan region of Salvador, Bahia, Brazil
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Lanza, Fernanda Cardoso

; Ribeiro-Jr, Gilmar

; Miranda, Diego Lopes Paim

; Santos, Fred Luciano Neves

; Carvalho, Cristiane Medeiros Moraes de

; Cunha, Gabriel Muricy

; Carneiro, Ianei de Oliveira

; Reis, Renato Barbosa

; Cunha, José Maurício Albuquerque

; Cardoso, Cristiane Wanderley

; Soares, Jorgana Fernanda de Souza

; Araújo, Fernando Luiz Vieira de

; Reis, Mitermayer Galvão

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volumen 56 elocation e0185-2022

Resumen: En | Texto: En | PDF: En

ABSTRACT Background: Chagas disease (CD) is caused by Trypanosoma cruzi and transmitted by triatomines. Historical information from the 20th century demonstrates T. cruzi records in the metropolitan region of Salvador (MRS), the third largest urban agglomeration in the Brazilian Northeast and the eighth largest in Brazil, an area with intense migratory activity from CD-endemic regions. Therefore, this study aimed to evaluate CD indicators (prevalence and mortality) in the MRS. Methods: A mixed ecological and descriptive study was conducted using secondary data. We analyzed data from 2008 to 2015: deaths due to CD, self-reported cases of CD, and blood donors that were non-negative for T. cruzi infection. Results: São Francisco do Conde was one of the municipalities with the highest mortality rates due to CD. The seroprevalence rates varied by year and municipality; those with the highest values were 2008: Vera Cruz, 2009: Mata de São João, 2010: Dias D'Ávila, 2011 and 2015: São Francisco do Conde, 2012: São Sebastião do Passé, and 2013 and 2014: Pojuca. Spatial correlations between the municipalities were not detected. Conclusions: We conclude that CD is present in the MRS. The indicators analyzed in the MRS are below-state-level data. Given the importance of indicator analysis for the surveillance and control of CD at the state and national levels, it is important to strengthen the surveillance program at the municipal level, including the regions classified as low risk for T. cruzi vector transmission.

https://doi.org/10.1590/0037-8682-0185-2022

Carbon stocks and lability in land use and management systems in southwestern Goiás, Brazil
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Ribeiro, Diego Oliveira

; Gonçalves, Gabriel Rosa

; Rubio, Giovana Oliveira

; Castoldi, Gustavo

; Vendruscolo, Eduardo Pradi

; Souza, Zaqueu Henrique de

Pesquisa Agropecuária Tropical

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2023, Volumen 53 elocation e74416

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The southwest region of the Goiás state, Brazil, is suitable for several agricultural activities, even in more fragile soils such as Typic Quartzipsamments. This study aimed to evaluate the carbon stocks and lability of a Typic Quartzipsamment under land use and management systems in southwestern Goiás. The experiment was conducted in a completely randomized design and consisted of areas subjected to five land use and management systems [native Cerrado vegetation (Brazilian Savanna), pasture under intensive grazing, pasture under extensive grazing, soybean and maize rotation, and eucalyptus]. Soil samples were collected at the 0-0.1 and 0.1-0.2 m layers. The land use and management systems affected the carbon stocks and quality. In the 0-0.2 m layer, the carbon stocks ranged between 15.9 and 29.2 Mg ha−1. The areas with eucalyptus and under intensive grazing promoted increases in the carbon stocks that ranged between 72 and 84 %, when compared to the areas with Cerrado vegetation and soybean and maize rotation. The carbon contents in the F1, F2 and F4 fractions were higher in the areas with eucalyptus and under intensive grazing. In the 0-0.1 m soil layer, the areas with eucalyptus and under intensive grazing had an increase in the carbon management index by 33 and 36 %, respectively, when compared to the reference area with native Cerrado vegetation.

RESUMO O sudoeste do estado de Goiás apresenta elevada vocação para diversas atividades agropecuárias, mesmo em solos considerados mais frágeis, como os Neossolos Quartzarênicos. Objetivou-se avaliar os estoques e a labilidade de carbono em sistemas de uso e manejo de um Neossolo Quartzarênico, no sudoeste goiano. Utilizou-se delineamento inteiramente causualizado, constando de áreas submetidas a cinco sistemas de uso e manejo do solo (Cerrado nativo, pastagem intensiva, pastagem extensiva, plantio de soja com sucessão de milho, e eucalipto). Foram coletadas amostras nas profundidades de 0-0,1 e 0,1-0,2 m. Os sistemas de uso e manejo do solo alteraram os estoques e a qualidade do carbono. Na camada de 0-0,2 m, os estoques de carbono variaram entre 15,9 e 29,2 Mg ha−1. As áreas com eucalipto e sob pastejo intensivo proporcionaram incrementos variando entre 72 e 84 % nos estoques de carbono, em relação às áreas de Cerrado e soja-milho. Os teores de carbono nas frações F1, F2 e F4 foram superiores nas áreas com eucalipto e sob pastejo intensivo. Na camada de 0-0,1 m, as áreas com cultivo de eucalipto e sob pastejo intensivo incrementaram o índice de manejo de carbono em 33 e 36 %, respectivamente, quando comparadas à área de referência com Cerrado nativo.

https://doi.org/10.1590/1983-40632023v5374416

Searching for new antifungals for the treatment of cryptococcosis
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Sousa, Naira Sulany Oliveira de

; Almeida, Juan Diego Ribeiro de

; Frickmann, Hagen

; Lacerda, Marcus Vinícius Guimarães

; Souza, João Vicente Braga de

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volumen 56 elocation e0121-2023

Resumen: En | Texto: En | PDF: En

ABSTRACT There is a consensus that the antifungal repertoire for the treatment of cryptococcal infections is limited. Standard treatment involves the administration of an antifungal drug derived from natural sources (i.e., amphotericin B) and two other drugs developed synthetically (i.e., flucytosine and fluconazole). Despite treatment, the mortality rates associated with fungal cryptococcosis are high. Amphotericin B and flucytosine are toxic, require intravenous administration, and are usually unavailable in low-income countries because of their high cost. However, fluconazole is cost-effective, widely available, and harmless with regard to its side effects. However, fluconazole is a fungistatic agent that has contributed considerably to the increase in fungal resistance and frequent relapses in patients with cryptococcal meningitis. Therefore, there is an unquestionable need to identify new alternatives or adjuvants to conventional drugs for the treatment of cryptococcosis. A potential antifungal agent should be able to kill cryptococci and “bypass” the virulence mechanism of the yeast. Furthermore, it should have fungicidal action, low toxicity, high selectivity, easily penetrate the central nervous system, and widely available. In this review, we describe cryptococcosis, its conventional therapy, and failures arising from the use of drugs traditionally considered to be the reference standard. Additionally, we present the approaches used for the discovery of new drugs to counteract cryptococcosis, ranging from the conventional screening of natural products to the inclusion of structural modifications to optimize anticryptococcal activity, as well as drug repositioning and combined therapies.

https://doi.org/10.1590/0037-8682-0121-2023

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volumen 37 elocation e126

Resumen: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

RESECTION OF ANKLE TUMOR LESION AND RECONSTRUCTION WITH THE USE OF ALLOGRAFT
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MOTTA, DIEGO PEREZ DA

; ARRUDA, BEATRIZ GOMES

; PINHEIRO, RAFAEL DE CASTRO E SILVA

; RIBEIRO, GABRIEL ARAÚJO

; DELOCCO, BRUNA CANTERI

; FIORELLI, BRUNO DE OLIVEIRA

; WITTE, EDUARDO ALESSANDRO LIMA

; MEOHAS, WALTER

Acta Ortopédica Brasileira

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2023, Volumen 31 Nº 5 elocation e266018

Resumen: En | Texto: En | PDF: En

RESUMO A reconstrução do terço distal da tíbia devido à ressecção de tumor maligno apresenta alguns fatores que dificultam sua realização, como camada subcutânea delgada, feixes neurovasculares que transpassam os compartimentos, tempo cirúrgico prolongado, material ortopédico específico e equipe multidisciplinar treinada. O aloenxerto de banco de tecido faz parte deste arsenal ortopédico. Objetivo: Descrever o protocolo realizado no Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad. Métodos: Série de seis casos submetidos à ressecção com margens oncológicas, reconstrução com aloenxerto e uso de haste retrógrada de tornozelo como cirurgia preservadora do membro. Três dos seis pacientes eram do sexo feminino, as lesões tinham em média 9,3 cm de comprimento e o tempo cirúrgico médio foi de 3,25 horas. Resultados: A principal complicação de curto prazo (≤ 30 dias) foi a paralisia do nervo fibular, enquanto a principal complicação de longo prazo (> 30 dias) foi a infecção do sítio cirúrgico (dois casos). A consolidação dos dois focos ocorreu em três pacientes, e dois pacientes evoluíram para pseudoartrose assintomática do foco proximal com consolidação do foco distal. Conclusão: Apesar das complicações, a cirurgia proposta permite ao paciente a chance de preservar seu membro diante de uma cirurgia radical imediata. Nível de Evidência IV, Série de Casos.

https://doi.org/10.1590/1413-785220233105e266018

Women Brazilian Jiu-jitsu practitioners showed a higher incidence of concussion: an epidemiological analysis
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Carvalho, Gustavo Nascimento de

; Rego, Rafael da Silva

; Chagas, Ana

; Schreiner, Diana de Oliveira

; Teixeira, Felipe Guimarães

; Antonietto, Naiara Ribeiro

; Pérez, Diego Ignacio Valenzuela

; Brito, Ciro José

; Miarka, Bianca

Motricidade

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Dic 2022, Volumen 18 Nº 2 Paginas 151 - 155

Resumen: En | Texto: En | PDF: En

Abstract Knowledge about the prevalence of concussion in combat sports is important information to keep athletes’ and practitioners’ physical integrity in different modalities such as Brazilian jiu-jitsu (BJJ). Therefore, this study aimed to compare concussions incidence in BJJ between men and women practitioners. A randomized sample of 779 (689 men and 90 women) BJJ practitioners (age: 32.4± 9.8 years, training-time: 57.3± 54.4 months, training frequency: 3.4± 1.3 times/week). The injury analysis was done using a questionnaire with demographic data and a survey about concussions. The main results showed that women had a significantly higher frequency of concussions in training than men [38 (41%) women vs 147 men (20,5%); p ≤ 0.001]. Furthermore, women had a significantly higher frequency of loss of consciousness than men [13 (8.8%) men vs 4 (11%) women; p = 0.009], among the symptoms resulting from a concussion, headache, dizziness, and loss of balance, represented the most common symptoms in those affected by concussion, regardless of gender. The results of this study may be helpful to athletes, coaches, and federations to prevent this type of injury, mainly in women.

https://doi.org/10.6063/motricidade.25225

10.

IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva
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Tomazini, Bruno M

; Nassar Jr, Antonio Paulo

; Lisboa, Thiago Costa

; Azevedo, Luciano César Pontes de

; Veiga, Viviane Cordeiro

; Catarino, Daniela Ghidetti Mangas

; Fogazzi, Debora Vacaro

; Arns, Beatriz

; Piastrelli, Filipe Teixeira

; Dietrich, Camila

; Negrelli, Karina Leal

; Jesuíno, Isabella de Andrade

; Reis, Luiz Fernando Lima

; Mattos, Renata Rodrigues de

; Pinheiro, Carla Cristina Gomes

; Luz, Mariane Nascimento

; Spadoni, Clayse Carla da Silva

; Moro, Elisângela Emilene

; Bueno, Flávia Regina

; Sampaio, Camila Santana Justo Cintra

; Silva, Débora Patrício

; Baldassare, Franca Pellison

; Silva, Ana Cecilia Alcantara

; Veiga, Thabata

; Barbante, Leticia

; Lambauer, Marianne

; Campos, Viviane Bezerra

; Santos, Elton

; Santos, Renato Hideo Nakawaga

; Laranjeiras, Ligia Nasi

; Valeis, Nanci

; Santucci, Eliana

; Miranda, Tamiris Abait

; Patrocínio, Ana Cristina Lagoeiro do

; Carvalho, Andréa de

; Sousa, Eduvirgens Maria Couto de

; Sousa, Ancelmo Honorato Ferraz de

; Malheiro, Daniel Tavares

; Bezerra, Isabella Lott

; Rodrigues, Mirian Batista

; Malicia, Julliana Chicuta

; Silva, Sabrina Souza da

; Gimenes, Bruna dos Passos

; Sesin, Guilhermo Prates

; Zavascki, Alexandre Prehn

; Sganzerla, Daniel

; Medeiros, Gregory Saraiva

; Santos, Rosa da Rosa Minho dos

; Silva, Fernanda Kelly Romeiro

; Cheno, Maysa Yukari

; Abrahão, Carolinne Ferreira

; Oliveira Junior, Haliton Alves de

; Rocha, Leonardo Lima

; Nunes Neto, Pedro Aniceto

; Pereira, Valéria Chagas

; Paciência, Luis Eduardo Miranda

; Bueno, Elaine Silva

; Caser, Eliana Bernadete

; Ribeiro, Larissa Zuqui

; Fernandes, Caio Cesar Ferreira

; Garcia, Juliana Mazzei

; Silva, Vanildes de Fátima Fernandes

; Santos, Alisson Junior dos

; Machado, Flávia Ribeiro

; Souza, Maria Aparecida de

; Ferronato, Bianca Ramos

; Urbano, Hugo Corrêa de Andrade

; Moreira, Danielle Conceição Aparecida

; Souza-Dantas, Vicente Cés de

; Duarte, Diego Meireles

; Coelho, Juliana

; Figueiredo, Rodrigo Cruvinel

; Foreque, Fernanda

; Romano, Thiago Gomes

; Cubos, Daniel

; Spirale, Vladimir Miguel

; Nogueira, Roberta Schiavon

; Maia, Israel Silva

; Zandonai, Cassio Luis

; Lovato, Wilson José

; Cerantola, Rodrigo Barbosa

; Toledo, Tatiana Gozzi Pancev

; Tomba, Pablo Oscar

; Almeida, Joyce Ramos de

; Sanches, Luciana Coelho

; Pierini, Leticia

; Cunha, Mariana

; Sousa, Michelle Tereza

; Azevedo, Bruna

; Dal-Pizzol, Felipe

; Damasio, Danusa de Castro

; Bainy, Marina Peres

; Beduhn, Dagoberta Alves Vieira

; Jatobá, Joana D’Arc Vila Nova

; Moura, Maria Tereza Farias de

; Rego, Leila Rezegue de Moraes

; Silva, Adria Vanessa da

; Oliveira, Luana Pontes

; Sodré Filho, Eliene Sá

; Santos, Silvana Soares dos

; Neves, Itallo de Lima

; Leão, Vanessa Cristina de Aquino

; Paes, João Lucidio Lobato

; Silva, Marielle Cristina Mendes

; Oliveira, Cláudio Dornas de

; Santiago, Raquel Caldeira Brant

; Paranhos, Jorge Luiz da Rocha

; Wiermann, Iany Grinezia da Silva

; Pedroso, Durval Ferreira Fonseca

; Sawada, Priscilla Yoshiko

; Prestes, Rejane Martins

; Nascimento, Glícia Cardoso

; Grion, Cintia Magalhães Carvalho

; Carrilho, Claudia Maria Dantas de Maio

; Dantas, Roberta Lacerda Almeida de Miranda

; Silva, Eliane Pereira

; Silva, Antônio Carlos da

; Oliveira, Sheila Mara Bezerra de

; Golin, Nicole Alberti

; Tregnago, Rogerio

; Lima, Valéria Paes

; Silva, Kamilla Grasielle Nunes da

; Boschi, Emerson

; Buffon, Viviane

; Machado, André Sant’Ana

; Capeletti, Leticia

; Foernges, Rafael Botelho

; Carvalho, Andréia Schubert de

; Oliveira Junior, Lúcio Couto de

; Oliveira, Daniela Cunha de

; Silva, Everton Macêdo

; Ribeiro, Julival

; Pereira, Francielle Constantino

; Salgado, Fernanda Borges

; Deutschendorf, Caroline

; Silva, Cristofer Farias da

; Gobatto, Andre Luiz Nunes

; Oliveira, Carolaine Bomfim de

; Dracoulakis, Marianna Deway Andrade

; Alvaia, Natália Oliveira Santos

; Souza, Roberta Machado de

; Araújo, Larissa Liz Cardoso de

; Melo, Rodrigo Morel Vieira de

; Passos, Luiz Carlos Santana

; Vidal, Claudia Fernanda de Lacerda

; Rodrigues, Fernanda Lopes de Albuquerque

; Kurtz, Pedro

; Shinotsuka, Cássia Righy

; Tavares, Maria Brandão

; Santana, Igor das Virgens

; Gavinho, Luciana Macedo da Silva

; Nascimento, Alaís Brito

; Pereira, Adriano J

; Cavalcanti, Alexandre Biasi

Revista Brasileira de Terapia Intensiva

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Dic 2022, Volumen 34 Nº 4 Paginas 418 - 425

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials.

RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos.

https://doi.org/10.5935/0103-507x.20220209-pt

11.

PHYSICAL FRACTIONATION AND CARBON AND NITROGEN STOCKS IN SOIL AFTER POULTRY WASTE APPLICATIONS
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RIBEIRO, DIEGO OLIVEIRA

; CASTOLDI, GUSTAVO

; FREIBERGER, MARIÂNGELA BRITO

; SILVA, MELLISSA ANANIAS SOLER DA

; RODRIGUES, CARLOS RIBEIRO

Revista Caatinga

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Sep 2022, Volumen 35 Nº 3 Paginas 667 - 676

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Resíduos da produção de peru frequentemente são utilizados como fertilizantes em pastagens próximas a regiões produtoras. Esses resíduos podem contribuir para a elevação dos estoques de carbono e nitrogênio no solo. Neste estudo objetivou-se avaliar os efeitos acumulados de nove aplicações de doses de cama de peru nas frações e estoques de C e N em um Latossolo Vermelho distroférrico, sob pastejo rotacionado. A área experimental foi dividida em 16 piquetes de 0.5 ha cada, e cultivada com Urochloa decumbens em sistema de pastejo rotativo. Os tratamentos consistiram em doses acumuladas de cama de peru (38.3; 54.8 e 69.2 Mg ha−1), com aplicações realizadas entre 2008 e 2017, além de um tratamento controle, sem aplicação desse material. Os estoques de carbono orgânico total (TOC), nitrogênio total (TN) no solo aumentaram à medida que se aumentou as doses de cama de peru, chegando a incrementos, na camada de 0-0.2 m, de 11.2 Mg ha−1 e 1.03 Mg ha−1, respectivamente, quando comparados ao tratamento controle. Na mesma camada de 0-0.2 m, os máximos incrementos nos estoques de carbono na matéria orgânica particulada (POC) e nitrogênio na matéria orgânica particulada (N-POM) foram obtidos com as doses totais estimadas de 62 e 66 Mg ha−1, respectivamente. Além de aumentar a quantidade, o uso da cama de peru resultou em melhoria da qualidade do carbono presente no solo, uma vez que o índice de manejo de carbono, na camada de 0-0.2 m, foi aumentado em 124 %, quando do uso da maior dose acumulada.

ABSTRACT Residues from turkey production are often used as fertilizers in pastures near producing regions. These residues can contribute to the increase of carbon and nitrogen stocks in the soil. This study aimed to evaluate the cumulative effects of nine applications of turkey litter rates on C and N fractions and stocks in a Latossolo Vermelho distroférrico (Oxisol) cultivated under rotational grazing. The experimental area was divided into 16 pickets of 0.5 ha each and cultivated with Urochloa decumbens in a rotational grazing system. The treatments consisted of accumulated doses of turkey litter (38.3; 54.8 and 69.2 Mg ha−1), with applications carried out between 2008 and 2017, in addition to a control treatment, without application of this material. After nine years of application, total organic carbon (TOC) and total nitrogen (TN) stocks in the soil increased as turkey litter rates increased, reaching increments in the 0-0.2 m layer of 11.2 Mg ha−1 and 1.03 Mg ha−1, respectively, when compared to the control treatment. In the same 0-0.2 m layer, the maximum increments in carbon stock in particulate organic matter (POC) and nitrogen stock in particulate organic matter (N-POM) were obtained with the estimated total doses of 62 and 66 Mg ha−1, respectively. In addition to increasing the amount, the use of turkey litter improved the quality of the carbon present in the soil, since the carbon management index, in the 0-0.2 m layer, was increased by 124% when using the highest accumulated dose.

https://doi.org/10.1590/1983-21252022v35n318rc

12.

Anatomical Study of the Medial Region of the Knee: Qualitative, Quantitative Analysis and Description of the Anterior Oblique Ligament
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Jorge, Pedro Baches

; Silva, Marconde de Oliveira e

; Horita, Melanie Mayumi

; Resende, Vanessa Ribeiro de

; Guglielmetti, Luiz Gabriel Betoni

; Oliveira, Diego Escudeiro de

Revista Brasileira de Ortopedia

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Ago 2022, Volumen 57 Nº 4 Paginas 682 - 688

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Descrever todas as estruturas ligamentares, capsulares, tendinosas e marcos ósseos da região medial do joelho, assim como uma nova estrutura ligamentar identificada em uma série de dissecções anatômicas de espécimes cadavéricos. Métodos Vinte joelhos de cadáveres foram dissecados para estudar o compartimento medial. As principais estruturas dessa região foram identificadas durante a dissecção. A morfologia das estruturas e sua relação com parâmetros anatômicos conhecidos foram determinados tanto de forma qualitativa quanto de forma quantitativa. Os dados coletados foram analisados e interpretados por meio de estatística descritiva. Resultados Na dissecção de todos os espécimes, foram identificadas todas as estruturas ligamentares já descritas anteriormente no estudo anatômico da porção medial do joelho, e foram realizadas medidas objetivas que podem auxiliar como parâmetros para a reconstrução ligamentar cirúrgica. Foram observados e descritos, ainda, ao se desprender o ligamento colateral medial superficial, uma proeminência óssea imediatamente distal à sua inserção tibial proximal, uma bursa abaixo do ligamento, na qual o mesmo não se mostrava inserido, assim como uma estrutura ligamentar localizada extracapsularmente e com origem na face anterior do epicôndilo medial, seguindo obliquamente em direção à tíbia, aos quais foram dados os nomes, respectivamente, de tubérculo interinsercional, bursa interinsercional e ligamento oblíquo anterior. Conclusão Além da descrição e medida das estruturas e parâmetros já existentes no estudo anatômico da porção medial do joelho, foi possível a descrição de três novas estruturas: o tubérculo interinsercional a bursa interinsercional e o ligamento oblíquo anterior, ainda não descritos na literatura. Essas estruturas foram encontradas em todas as dissecções realizadas.

Abstract Objective To describe all ligamentous, capsular, tendinous and bone landmarks structures of the medial region of the knee, as well as a new ligamentous structure identified in a series of anatomical dissections of cadaveric specimens. Methods Twenty cadaver knees were dissected to study the medial compartment. The main structures of this region were identified during dissection. The morphology of the structures and their relationship with known anatomical parameters were determined both qualitatively and quantitatively. The collected data were analyzed and interpreted using descriptive statistics. Results In the dissection of all specimens, all ligamentous structures previously described in the anatomical study of the medial part of the knee were identified, and objective measures that can help as parameters for surgical ligament reconstruction were identified. When dissecting the medial collateral ligament, a bony prominence immediately distal to its proximal tibial insertion was observed and described, as well as a bursa below the ligament, in which it was not inserted. We also described a ligamentous structure with extracapsular location, originated anteriorly to the medial epicondyle and following obliquely towards the tibia. These structures were named, respectively, interinsertional tubercle, interinsertional bursa and anterior oblique ligament. Conclusion In addition to the description and measurement of the structures and parameters already existing in the anatomical study of the medial part of the knee, it was possible to describe three new structures not yet described in the literature: the interinsertional tubercle, the interinsertional bursa, and the anterior oblique ligament. These structures were found in all dissections performed.

https://doi.org/10.1055/s-0041-1731419

13.

Health-Related Quality of Life Reported by Patients With Chagas Disease: A Systematic Review of Qualitative Evidence With GRADE Recommendations
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Silva, Whesley Tanor

; Oliveira, Lucas Frois Fernandes

; Xavier, Diego Mendes

; Figueiredo, Pedro Henrique Scheidt

; Lacerda, Ana Cristina Rodrigues

; Mendonça, Vanessa Amaral

; Ávila, Matheus Ribeiro

; Ferreira Júnior, Cláudio Luiz

; Lima, Márcia Maria Oliveira

; Mediano, Mauro Felippe Felix

; Rocha, Manoel Otávio da Costa

; Costa, Henrique Silveira

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volumen 55 elocation e0377-2022

Resumen: En | Texto: En | PDF: En

ABSTRACT Patients with Chagas disease have reduced health-related quality of life (HRQoL). Hence, we aimed to identify the factors that mostly affected their HRQoL. This was a systematic review of qualitative studies. The Latin American and Caribbean Health Sciences Literature, Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Web of Science, and SciVerse Scopus databases were searched for relevant studies without language or date restrictions. The search and data analysis were performed by independent reviewers; all qualitative studies that reported the factors that had an impact on the HRQoL of patients with Chagas disease were included. The risk of bias was assessed using the Critical Appraisal Skills Program Qualitative Study Checklist; confidence in the evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation-Confidence in the Evidence from Reviews of Qualitative approach. Five studies were included in this review: four in Brazil and one in California, United States, with immigrants from Central and South America. The sample consisted of 207 patients with chronic Chagas disease. Stigma, physical limitations, work absenteeism, emotional or mental aspects, fear of treatment, and fear of the future had the strongest impact on the HRQoL. All items showed moderate confidence except for fear of treatment (low confidence). The physical, emotional, mental, and cultural aspects affected the HRQoL of patients with chronic Chagas disease. Identification of these factors is important in the development of strategies aimed at improving the HRQoL of this population.

https://doi.org/10.1590/0037-8682-0377-2022

14.

Cardiovascular Risk and Factors Associated to the Health in Hypertensive African Descent People Resident in Quilombola Community
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Rosa, Randson Souza

; Ribeiro Ícaro, José do Santos

; Silva, Jaine Kareny da

; Souza, Luiz Humberto Rodrigues

; Cruz, Diego Pires

; Damasceno, Rudson Oliveira

; Junior, Edison Vitório de Souza

; Boery, Rita Narriman Silva de Oliveira

Revista Cuidarte

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Ago 2021, Volumen 12 Nº 2 elocation e1165

Resumen: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Introdução A hipertensão é um fator de risco cardiovascular de ampla magnitude entre pessoas de ascendência africana, principalmente, as que vivem em Quilombos. No entanto, pouco se sabe sobre os fatores associados ao risco cardiovascular em residentes na comunidade Quilombola urbana. Objetivo Analisar o risco cardiovascular e fatores associados à saúde no contexto familiar de descendentes africanos hipertensos que vivem em uma comunidade Quilombola urbana. Material e métodos Trata-se de um estudo censitário de base comunitária, realizado de novembro de 2017 a março de 2018. A população do estudo foi composta por 303 pacientes hipertensos matriculados na unidade de saúde da família, com idades entre 35 e 79 anos, ambos os sexos; e em uso de medicamentos anti-hipertensivos. Os instrumentos utilizados para produzir os dados foram: o Questionário de Hipertensão na Atenção Primária, e o escore de risco de Framingham . Resultados Foi observada associação significativa entre risco cardiovascular e histórico familiar de doença cardiovascular (DCV) (p <0,011), diabetes tipo II (p <0,001) e sobrepeso e obesidade (p <0,010). Conclusão A pesquisa mostrou que pessoas hipertensas quilombolas apresentam resultados consistentes em relação ao risco cardiovascular, principalmente com a inclusão de histórico familiar de DCV, diabetes tipo II, sobrepeso e obesidade, educação e sexo com associações significativas.

Abstract Introduction Hypertension is a cardiovascular risk factor of wide magnitude among people of African descent, especially those living in Quilombos. However, little is known about the factors associated with cardiovascular risk in residents of the urban Quilombola community. Objetive To analyze the cardiovascular risk and health-related factors in the family context of hypertensive Afro-descendants living in an urban Quilombola. Materials and methods It is a cross-sectional and community-based study carried out from November 2017 to March 2018. The study's population consisted of 303 hypertensive patients enrolled in the family health unit, with ages ranging from 35 to 79 years old, of both genders; and using antihypertensive drugs. The instruments used for data production were: The Primary Arterial Hypertension Questionnaire and the Framingham Risk Score . Results There was a significant association between cardiovascular risk and cardiovascular disease (CVD) family history (p<0.011), type II diabetes (p<0.001) and overweight and obesity (p<0.010). Conclusion Research has shown that hypertensive Quilombola people have consistent cardiovascular risk outcomes, especially with CVD family history, type II diabetes, overweight and obesity, schooling and gender with significant associations.

Resumen Introducción La hipertensión es un factor de riesgo cardiovascular de gran magnitud entre las personas de ascendencia africana, especialmente las que viven en quilombos. Sin embargo, se sabe poco sobre los factores asociados con el riesgo cardiovascular en los residentes de la comunidad urbana Quilombola. Objetivo Analizar el riesgo cardiovascular y los factores asociados con la salud en el contexto familiar de los descendientes africanos hipertensos que viven en una comunidad urbana de Quilombolas. Material y métodos Este es un estudio transversal y basado en la comunidad, realizado desde noviembre de 2017 hasta marzo de 2018. La población de estudio consistió en 303 pacientes hipertensos inscritos en la unidad de salud familiar, de edad de 35 a 79 años, ambos sexos; y en el uso medicamentos antihipertensivos. Los instrumentos utilizados para producir los datos fueron: el Cuestionario de Hipertensión en Atención Primaria, la puntuación de riesgo de Framingham . Resultados Se observó una asociación significativa entre el riesgo cardiovascular y los antecedentes familiares de enfermedad cardiovascular (ECV) (p <0.011), diabetes tipo II (p <0.001) y sobrepeso y obesidad (p <0.010). Conclusión La investigación mostró que las personas Quilombolas hipertensos tienen resultados consistentes con respecto al riesgo cardiovascular, especialmente con la inclusión de antecedentes familiares de ECV, diabetes tipo II, sobrepeso y obesidad, educación y sexo con asociaciones significativas.

https://doi.org/10.15649/cuidarte.1165 44 descargas

15.

Hydrological modeling in a basin of the Brazilian Cerrado biome
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Rodrigues, Jéssica Assaid Martins

; Andrade, Alberto Carlos de Oliveira

; Viola, Marcelo Ribeiro

; Ferreira, Danton Diego

; Mello, Carlos Rogério de

; Thebaldi, Michael Silveira

Revista Ambiente & Água

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2021, Volumen 16 Nº 1 elocation e2639

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O bioma Cerrado brasileiro (BCB) está entre os 25 hotspots de biodiversidade identificados em todo o mundo, e abrange a área de recarga de importantes aqüíferos e rios da América do Sul. O aumento do desmatamento vem ameaçando a disponibilidade de água na região. A fim de auxiliar na gestão dos recursos hídricos da BCB, este estudo tem como objetivo modelar a vazão diária em uma bacia do Cerrado, utilizando duas abordagens: um modelo baseado em processo (Soil and Water Assessment Tool - SWAT) e um modelo orientado por dados (Artificial Neural Network - ANN). O desempenho dos modelos foi avaliado pelo coeficiente de Nash-Sutcliffe (NSE), coeficiente de determinação (R2) e curvas de duração de fluxo (FDC). Os resultados indicam que os modelos SWAT (NSE > 0,61; R2 > 0,68) e ANN (NSE > 0,91; R2 > 0,79) são ferramentas adequadas na modelagem diária de vazões da bacia estudada, sendo o modelo ANN o mais preciso. Com base no FDC, o modelo ANN também foi melhor do que o modelo SWAT para todas as frequências avaliadas. Assim, o modelo ANN é uma nova abordagem promissora para modelagem de fluxo diário nesta região. Além disso, os resultados deste estudo podem ajudar os gestores de recursos hídricos no planejamento e implementação de medidas adequadas de alocação e conservação de água no bioma Cerrado brasileiro.

Abstract The Brazilian Cerrado biome (BCB) is among 25 biodiversity hotspots identified worldwide, and covers the recharge area of important aquifers and rivers in South America. The increase in deforestation has been threatening water availability in this region. In order to assist in the water-resource management of the BCB, this study models the daily streamflow in a basin of the Cerrado, using two approaches: a process-based model (Soil and Water Assessment Tool - SWAT) and the data-driven model (Artificial Neural Network - ANN). The performance of the models was evaluated by the Nash-Sutcliffe coefficient (NSE), coefficient of determination (R2) and flow-duration-curves (FDC). The results indicate that SWAT (NSE > 0.61; R2 > 0.68) and ANN (NSE > 0.91; R2 > 0.79) models are suitable tools in daily streamflow modeling of the studied basin, with the ANN model being the most accurate. Based on FDC, the ANN model was also better than the SWAT model for all frequencies evaluated. Thus, the ANN model is a promising new approach for daily streamflow modelling in this region. Moreover, the results of this study can help water-resource managers in planning and implementing appropriate water allocation and conservation measures in the Brazilian Cerrado biome.

https://doi.org/10.4136/ambi-agua.2639 409 descargas

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