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Abstract Background Most of the evidence about the impact of the post-acute COVID-19 Syndrome (PACS) reports individual symptoms without correlations with related imaging. Objectives To evaluate cardiopulmonary symptoms, their predictors and related images in COVID-19 patients discharged from hospital. Methods Consecutive patients who survived COVID-19 were contacted 90 days after discharge. The Clinic Outcome Team structured a questionnaire evaluating symptoms and clinical status (blinded for hospitalization data). A multivariate analysis was performed to address the course of COVID-19, comorbidities, anxiety, depression, and post-traumatic stress during hospitalization, and cardiac rehabilitation after discharge. The significance level was set at 5%. Results A total of 480 discharged patients with COVID-19 (age: 59±14 years, 67.5% males) were included; 22.3% required mechanical ventilation. The prevalence of patients with PACS-related cardiopulmonary symptoms (dyspnea, tiredness/fatigue, cough, and chest discomfort) was 16.3%. Several parameters of chest computed tomography and echocardiogram were similar in patients with and without cardiopulmonary symptoms. The multivariate analysis showed that PACS-related cardiopulmonary-symptoms were independently related to female sex (OR 3.023; 95% CI 1.319-6.929), in-hospital deep venous thrombosis (OR 13.689; 95% CI 1.069-175.304), elevated troponin I (OR 1.355; 95% CI 1.048-1.751) and C-reactive protein during hospitalization (OR 1.060; 95% CI 1.023-1.097) and depression (OR 6.110; 95% CI 2.254-16.558). Conclusion PACS-related cardiopulmonary symptoms 90 days post-discharge are common and multifactorial. Beyond thrombotic and markers of inflammation/myocardial injury during hospitalization, female sex and depression were independently associated with cardiopulmonary-related PACS. These results highlighted the need for a multifaceted approach targeting susceptible patients.

Resumo Fundamento A maioria da evidência sobre o impacto da síndrome COVID pós-aguda (PACS, do inglês, post-acute COVID-19 syndrome) descreve sintomas individuais sem correlacioná-los com exames de imagens. Objetivos Avaliar sintomas cardiopulmonares, seus preditores e imagens relacionadas em pacientes com COVID-19 após alta hospitalar. Métodos Pacientes consecutivos, que sobreviveram à COVID-19, foram contatados 90 dias após a alta hospitalar. A equipe de desfechos clínicos (cega quanto aos dados durante a internação) elaborou um questionário estruturado avaliando sintomas e estado clínico. Uma análise multivariada foi realizada abordando a evolução da COVID-19, comorbidades, ansiedade, depressão, e estresse pós-traumático durante a internação, e reabilitação cardíaca após a alta. O nível de significância usado nas análises foi de 5%. Resultados Foram incluídos 480 pacientes (idade 59±14 anos, 67,5% do sexo masculino) que receberam alta hospitalar por COVID-19; 22,3% necessitaram de ventilação mecânica. A prevalência de pacientes com sintomas cardiopulmonares relacionados à PACS (dispneia, cansaço/fadiga, tosse e desconforto no peito) foi de 16,3%. Vários parâmetros de tomografia computadorizada do tórax e de ecocardiograma foram similares entre os pacientes com e sem sintomas cardiopulmonares. A análise multivariada mostrou que sintomas cardiopulmonares foram relacionados de maneira independente com sexo feminino (OR 3,023; IC95% 1,319-6,929), trombose venosa profunda durante a internação (OR 13,689; IC95% 1,069-175,304), nível elevado de troponina (OR 1,355; IC95% 1,048-1,751) e de proteína C reativa durante a internação (OR 1,060; IC95% 1,023-1,097) e depressão (OR 6,110; IC95% 2,254-16,558). Conclusão Os sintomas cardiopulmonares relacionados à PACS 90 dias após a alta hospitalar são comuns e multifatoriais. Além dos marcadores trombóticos, inflamatórios e de lesão miocárdica durante a internação, sexo feminino e depressão foram associados independentemente com sintomas cardiopulmonares relacionados à PACS. Esses resultados destacaram a necessidade de uma abordagem multifacetada direcionada a pacientes susceptíveis.

https://doi.org/10.36660/abc.20220642

Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Rassi, Daniela do Carmo

; Bragança, Érika Olivier Vilela

; Moura, Lidia Zytynski

; Arrais, Magaly

; Campos, Milena dos Santos Barros

; Lemke, Viviana Guzzo

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Almeida, André Luiz Cerqueira de

; Brandão, Andréa Araujo

; Ferreira, Andrea Dumsch de Aragon

; Biolo, Andreia

; Macedo, Ariane Vieira Scarlatelli

; Falcão, Breno de Alencar Araripe

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Marques-Santos, Celi

; Freire, Claudia Maria Vilas

; Pellegrini, Denise

; Alexandre, Elizabeth Regina Giunco

; Braga, Fabiana Goulart Marcondes

; Oliveira, Fabiana Michelle Feitosa de

; Cintra, Fatima Dumas

; Costa, Isabela Bispo Santos da Silva

; Silva, José Sérgio Nascimento

; Carreira, Lara Terra F.

; Magalhães, Lucelia Batista Neves Cunha

; Matos, Luciana Diniz Nagem Janot de

; Assad, Marcelo Heitor Vieira

; Barbosa, Marcia M.

; Silva, Marconi Gomes da

; Rivera, Maria Alayde Mendonça

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Paiva, Maria Sanali Moura de Oliveira

; Castro, Marildes Luiza de

; Uellendahl, Marly

; Oliveira Junior, Mucio Tavares de

; Souza, Olga Ferreira de

; Costa, Ricardo Alves da

; Coutinho, Ricardo Quental

; Silva, Sheyla Cristina Tonheiro Ferro da

; Martins, Sílvia Marinho

; Brandão, Simone Cristina Soares

; Buglia, Susimeire

; Barbosa, Tatiana Maia Jorge de Ulhôa

; Nascimento, Thais Aguiar do

; Vieira, Thais

; Campagnucci, Valquíria Pelisser

; Chagas, Antonio Carlos Palandri

Arquivos Brasileiros de Cardiologia

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2023, Volumen 120 Nº 7 elocation e20230303

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230303

Filling a gap: endophytic fungal diversity in the leaves of Miconia mirabilis in the Atlantic Forest (Brazil) and the description of a new Muyocopron species
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Ferro, Layanne O.

; O. Junior, Isaias

; Cavalcanti, Anthony Dias

; Cavalcante, Larissa O.

; Oliveira, Thays Gabrielle Lins de

; Paiva, Laura Mesquita

; Souza-Motta, Cristina M.

; Bezerra, Jadson D.P.

Acta Botanica Brasilica

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2023, Volumen 37 elocation e20230101

Resumen: En | Texto: En | PDF: En

Abstract Brazilian biomes, such as the Atlantic Forest, are hotspots for microbial diversity. Fungi at some stages of their life cycle can inhabit the interior of plants without apparent damage and are called endophytes. This study aimed to verify the culturable diversity of endophytic fungi present in the leaves of Miconia mirabilis in a conservation unit of the Atlantic Forest, in Northeast Brazil. A total of 273 endophytes were isolated, and 88 % of the estimated richness was recovered from 40 taxa with a Shannon diversity index of H′ = 2.79. The most abundant order was Xylariales (37.73 %), with Xylaria cf. cubensis being the most abundant species, followed by Glomerellales (14.65 %), Eurotiales (3.66 %), and Diaporthales (3.33 %). Additionally, a novel endophytic fungal species of Muyocopron was identified. Our results indicate the potential of endophytic diversity in the plants of tropical forests, reinforcing the need for further studies to better understand their ecological relationships.

https://doi.org/10.1590/1677-941x-abb-2023-0101

Lipid profile and reproductive performance of female offspring of SWISS mouse females supplemented with resveratrol or canjiqueira (Byrsonima cydoniifolia A Juss) during gestation
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MENEZES, ADRIANA C. GUERCIO

; BRANDÃO, LORENA S.R.

; PORTUGAL, LUCIANE C.

; MATSUBARA, LIDIA M.

; MAIA, ELAINE MARIA A.

; SAKODA, JHESSICA N.

; PROVIDELO, GILSON A.

; NAVAREZI, AMANDA G.

; SANTOS, KELY CRISTINA N. DOS

; GUIMARÃES, RITA DE CÁSSIA A.

; SOUZA, ALBERT S. DE

; SOUZA, MARIA INÊS L.

Anais da Academia Brasileira de Ciências

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2023, Volumen 95 Nº 4 elocation e20190804

Resumen: En | Texto: En | PDF: En

Abstract This study aimed to resveratrol supplementation (at 5 or 10 mg/kg) and a hydroethanolic extract of canjiqueira fruits (150 mg/kg) on female SWISS mice. Total cholesterol, high-density lipoprotein (HDL), triglyceride levels, gestation rates, and embryonic implantation rates in their female Offspring was evaluated. In conclusion, the consumption of canjiqueira fruit extract altered the lipid profile of their female offspring, and did not impact their reproductive performance. Supplementing female SWISS mice with 10 mg/kg of resveratrol increased total cholesterol, triglycerides, and HDL levels, thereby enhancing the reproductive efficiency of their offspring.

https://doi.org/10.1590/0001-3765202320190804

Anthelmintic treatment follow up in a rural community in Camamu, Bahia, Brazil
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FARIAS, MARINA M.B.

; BARRETO, NILO MANOEL P.V.

; ARAÚJO, WESLEI A.C.

; OLIVEIRA, CÍNTIA DE LIMA

; GONÇALVES, NOILSON LÁZARO S.

; CAMPAGNOLLO, KAMILA S.S.

; TEIXEIRA, MÁRCIA CRISTINA A.

; GALVÃO-CASTRO, BERNARDO

; SOARES, NECI M.

; SOUZA, JOELMA N. DE

Anais da Academia Brasileira de Ciências

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2023, Volumen 95 Nº 3 elocation e20230323

Resumen: En | Texto: En | PDF: En

Abstract Enteroparasites are an important public health problem and the treatment seeks to cure and reduce transmission. The aim of this study was to evaluate the therapeutic efficacy of anthelmintic treatment in individuals living in a rural community area in Camamu, Bahia, Brazil. The parasitological diagnosis was performed by spontaneous sedimentation, Baermann-Moraes and Agar Plate Culture methods. A total of 212 individuals were evaluated. The most frequent helminth was Trichuris trichiura, 24.5% (52/212), followed by Ascaris lumbricoides, 21.2% (45/212), hookworms, 16.5% (35/212), and S. stercoralis, 4.7% (10/212). In the anthelmintic treatment follow up, T. trichiura infection presented the lowest parasitological cure rate, only 60.6% (20/33). Hookworm, Ascaris lumbricoides and Strongyloides stercoralis infections demonstrated cure rates of 70.5 (12/17), 78.1 (25/32) and 100% (5/5), respectively. Individuals who remained infected underwent a new drug therapy. The second parasitological cure rate for T. trichiura was 38.5% (5/13), and 66.7% (2/3) and 75% (3/4) for hookworms and Ascaris lumbricoides, respectively. Trichuris trichiura infection presented the lowest parasitological cure rate at this second evaluation. This reinforces the need to perform a follow-up of all treated individuals. The possibility of drug resistance denotes the necessity for studies to clarify the mechanisms and to evaluate new therapeutic approaches.

https://doi.org/10.1590/0001-3765202320230323

Posicionamento sobre a Saúde Cardiovascular nas Mulheres – 2022
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Oliveira, Glaucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Marques-Santos, Celi

; Costa, Maria Elizabeth Navegantes Caetano

; Carvalho, Regina Coeli Marques de

; Freire, Cláudia Maria Vilas

; Magalhães, Lucelia Batista Neves Cunha

; Hajjar, Ludhmila Abrahão

; Rivera, Maria Alayde Mendonça

; Castro, Marildes Luiza de

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Lantieri, Carla Janice Baister

; Polanczyk, Carisi Anne

; Albuquerque, Carlos Japhet da Matta

; Born, Daniel

; Falcheto, Eduardo Belisário

; Bragança, Érika Olivier Vilela

; Braga, Fabiana Goulart Marcondes

; Colombo, Fernanda M. Consolim

; Jatene, Ieda Biscegli

; Costa, Isabela Bispo Santos da Silva

; Rivera, Ivan Romero

; Scholz, Jaqueline Ribeiro

; Melo Filho, José Xavier de

; Santos, Magaly Arrais dos

; Izar, Maria Cristina de Oliveira

; Azevedo, Maria Fátima

; Moura, Maria Sanali

; Campos, Milena dos Santos Barros

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rizk, Stéphanie Itala

; Rodrigues, Thais de Carvalho Vieira

; Salim, Thaís Rocha

; Lemke, Viviana de Mello Guzzo

Arquivos Brasileiros de Cardiologia

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Nov 2022, Volumen 119 Nº 5 Paginas 815 - 882

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220734

[SciELO Preprints] - Phalloid and floweroid funga (Phallales, Basidiomycota) in Bahia State, Brazil
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Ribeiro, Mateus Santana Cabral, Tiara Sousa Melanda, Gislaine Cristina Souza Baseia, Iuri Goulart Silva, Bianca Denise Barbosa da

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Fecha de publicación: 2022-08-30

Resumen: En Pt

The order Phallales harbors gasteroid fungi known as stinkhorns, false-truffles, witches’cages and bridal veils, and is mainly characterized by the fetid smelling basidiome, insect-associated dispersal mechanism, and mucilaginous gleba. The order has been well studied in Brazil, with greater occurrence in the southern and northeastern regions of the country. The state of  Bahia has only records of the species Abrachium floriforme and Lysurus sphaerocephalum. The objective of this study is to present new occurrences of Phallales for the State.  The species were collected in the Bahia State, in the municipalities of Elísio Medrado, Mucugê, Salvador and Uruçuca. One herborized specimen from Lençóis was included in the analyses. Seven species were identified: Abrachium floriforme, Itajahya galericulata, Mutinus caninus, M. elegans, M. verrucosus, Phallus denigricans and P. merulinus. All represent new occurrences for the State of Bahia, except A. floriforme. Descriptions, identification key, notes and photos of the species are provided.

A ordem Phallales abriga fungos gasteroides conhecidos como chifres-fedidos, falsas trufas, gaiolas-de-bruxa e véus-de-noiva, e é caracterizada principalmente pelo cheiro fétido do basidioma, mecanismo de dispersão associado a insetos e gleba mucilaginosa. A ordem tem sido bem estudada no Brasil, com maior ocorrência nas regiões Sul e Nordeste do país. O Estado da Bahia apresenta apenas registros das espécies Abrachium floriforme e Lysurus sphaerocephalum. O objetivo deste estudo é apresentar novas ocorrências de Phallales para o Estado.  As espécies foram coletadas na Bahia, nos municípios de Elísio Medrado, Mucugê, Salvador e Uruçuca. Um espécime herborizado coletado em Lençóis foi incluído nas análises. Sete espécies foram identificadas: Abrachium floriforme, Itajahya galericulata, Mutinus caninus, M. elegans, M. verrucosus, Phallus denigricans e P. merulinus. Todas representam novas ocorrências para o Estado da Bahia, com exceção de A. floriforme. Descrições, chave de identificação, notas e fotos das espécies são disponibilizadas.

https://doi.org/10.1590/2236-8906-14/2022

WSOC and Its Relationship with BC, Levoglucosan and Transition Metals in the PM2.5 of an Urban Area in the Amazon
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Fernandes, Karenn S.

; Santos, Erickson O. dos

; Batista, Carla E.

; Ribeiro, Igor O.

; Piracelli, Victor P.

; Solci, Maria Cristina

; Duvoisin Jr., Sergio

; Martin, Scot T.

; Souza, Rodrigo A. F.

; Machado, Cristine M. D.

Journal of the Brazilian Chemical Society

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Jun 2022, Volumen 33 Nº 6 Paginas 570 - 581

Resumen: En | Texto: En | PDF: En

Water-soluble organic carbon (WSOC) makes up a large mass fraction of the organic carbon in the aerosol and can influence important cloud processes in the atmosphere. The capacity of WSOC to form metallic complexes with transition metals is well known; however, its influence on the aerosol of urban areas in the Amazon region is not very well known. In this study, we investigated the relationship between WSOC, black carbon (BC), levoglucosan (LEV) and transition metals (Fe, Cu and Mn) present in the PM2.5 (particles with a diameter smaller than 2.5 µm) of an urban environment during the dry season in the central Amazon. Oxalic acid (C2) was used to identify the influence of transition metals on WSOC. The mean mass concentration value of the PM2.5 was 14.72 μg m-3 (2.11-31.68 μg m-3). The WSOC made up 58.34% of the PM2.5 mass, followed by BC (20.28%), and LEV (2.62%). The WSOC showed significant correlation with the transition metals analyzed (> 0.56), especially Mn with C2 (linear coefficient (R2) = 0.74). A multiple linear regression with WSOC, BC and LEV showed a strong linear correlation between them (R2 = 0.86), indicating the influence of biomass burning and vehicle traffic on the organic aerosol.

https://doi.org/10.21577/0103-5053.20220011

Utilidad de las pruebas analíticas en el diagnóstico de alergia a las proteínas de la leche de vaca
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Díaz, M. Cristina

; Lavrut, Alberto J.

; Slullitel, Pablo

; Souza, M. Verónica

Archivos argentinos de pediatría

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Feb 2022, Volumen 120 Nº 1 Paginas 31 - 40

Resumen: Es | Texto: Es | PDF: Es

RESUMEN Introducción. La alergia a las proteínas de la leche de vaca es la alergia alimentaria más frecuente en los niños y para su diagnóstico se emplean historia clínica dirigida y prueba de provocación oral (PPO), el dosaje sérico de inmunoglobulina E específica (sIgE) y pruebas cutáneas de puntura (SPT, por su sigla en inglés). Sin embargo, su utilidad diagnóstica es difícil de establecer en la población local. El objetivo fue evaluar la utilidad de las pruebas para el diagnóstico de alergia a las proteínas de la leche de vaca (PLV) en la población estudiada. Población y métodos. Análisis retrospectivo de datos de pacientes atendidos en la Unidad de Alergia del Hospital Elizalde entre 2015 y 2018. Se evaluaron SPT y sIgE para leche, alfa-lactoalbúmina, beta-lactoglobulina y caseína, seguidos de PPO y se determinó la utilidad diagnóstica para cada prueba, y sus combinaciones. Resultados. Se evaluaron las pruebas de 239 pacientes. La PPO fue hospitalaria en el 54,8 % de los casos, por reexposición domiciliara en el 35,5 % y en el 9,6 % por incorporación de PLV a la madre. La mayor especificidad fue la de SPT con caseína (96,7 %; intervalo de confianza [IC95%]: 90,8-99,3) y la mayor sensibilidad, la de la combinación de SPT y sIgE con los 4 alérgenos (55,3 %; IC95%: 45,7-64,6). Conclusiones. El trabajo estableció la utilidad diagnóstica de las SPT y el sIgE en la población estudiada.

https://doi.org/10.5546/aap.2022.21

10.

Association of the essential oil of Cymbopogon citratus (DC) Stapf with nystatin against oral cavity yeasts
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PAIVA, LUIZ FRANCISLEY DE

; TEIXEIRA-LOYOLA, ANA BEATRIZ A.

; SCHNAIDER, TAYLOR B.

; SOUZA, ANGÉLICA CRISTINA DE

; LIMA, LIDIANY M. ZACARONI

; DIAS, DISNEY R.

Anais da Academia Brasileira de Ciências

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2022, Volumen 94 Nº 1 elocation e20200681

Resumen: En | Texto: En | PDF: En

Abstract Oral thrush or candidiasis is a fairly common infectious fungal disease that is mainly caused by species of the genus Candida spp. In this work, we evaluated the antifungal activity of the essential oil of Cymbopogon citratus (DC) Stapf (lemongrass) and its combination with nystatin against oral cavity yeasts. The oil was extracted by the steam distillation method, and its constituents were quantified. The yeasts were identified using MALDI-TOF MS. The sensitivity to the essential oil and its association with nystatin was verified by the minimum inhibitory concentration (MIC) and checkerboard methods. In the essential oil samples, there were 84.53% of citral. A total of 64.77% of strains were identified as Candida albicans. On susceptibility tests, 83.55% of the yeast isolates were inhibited in concentrations of ≥16 µg/mL of nystatin. C. citratus’s oil was capable of inhibiting and killing all the isolates tested with concentrations that varied from 0.137 to 2.2 mg/mL. The association of oil and nystatin had an additive effect on more than 78% of the strains. The association of this herbal drug with nystatin potentialized the antifungal effect on yeast samples isolated from the oral cavity of oncologic patients.

https://doi.org/10.1590/0001-3765202220200681

11.

β-micrustoxin (Mlx-9), a PLA2 from Micrurus lemniscatus snake venom: biochemical characterization and anti-proliferative effect mediated by p53
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Santos, Natália Fernanda Teixeira dos

; Imberg, Andréia de Souza

; Mariano, Douglas Oscar Ceolin

; Moraes, Angelina Cirelli de

; Andrade-Silva, Jessica

; Fernandes, Cristina Maria

; Sobral, Ana Cláudia

; Giannotti, Karina Cristina

; Kuwabara, Wilson M. Tatagiba

; Pimenta, Daniel Carvalho

; Maria, Durvanei Augusto

; Sandoval, Maria Regina Lopes

; Afeche, Solange Castro

Journal of Venomous Animals and Toxins including Tropical Diseases

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2022, Volumen 28 elocation e20210094

Resumen: En | Texto: En | PDF: En

Abstract Background Endogenous phospholipases A2 (PLA2) play a fundamental role in inflammation, neurodegenerative diseases, apoptosis and cellular senescence. Neurotoxins with PLA2 activity are found in snake venoms from the Elapidae and Viperidae families. The mechanism of action of these neurotoxins have been studied using hippocampal and cerebellar neuronal cultures showing [Ca2+]i increase, mitochondrial depolarization and cell death. Astrocytes are rarely used as a model, despite being modulators at the synapses and responsible for homeostasis and defense in the central nervous system. Preserving the cell division ability, they can be utilized to study the cell proliferation process. In the present work cultured astrocytes and glioblastoma cells were employed to characterize the action of β-micrustoxin (previously named Mlx-9), a PLA2 isolated from Micrurus lemniscatus snake venom. The β-micrustoxin structure was determined and the cell proliferation, cell cycle phases and the regulatory proteins p53, p21 and p27 were investigated. Methods β-micrustoxin was characterized biochemically by a proteomic approach. Astrocytes were obtained by dissociation of pineal glands from Wistar rats; glioblastoma tumor cells were purchased from ATCC and Sigma and cultured in DMEM medium. Cell viability was evaluated by MTT assay; cell proliferation and cell cycle phases were analyzed by flow cytometry; p53, p21 and p27 proteins were studied by western blotting and immunocytochemistry. Results Proteomic analysis revealed fragments on β-micrustoxin that aligned with a PLA2 from Micrurus lemniscatus lemniscatus previously identified as transcript ID DN112835_C3_g9_i1/m.9019. β-micrustoxin impaired the viability of astrocytes and glioblastoma tumor cells. There was a reduction in cell proliferation, an increase in G2/M phase and activation of p53, p21 and p27 proteins in astrocytes. Conclusion These findings indicate that β-micrustoxin from Micrurus lemniscatus venom could inhibit cell proliferation through p53, p21 and p27 activation thus imposing cell cycle arrest at the checkpoint G2/M.

https://doi.org/10.1590/1678-9199-jvatitd-2021-0094

12.

Applying colorimetry for wood differentiation of fabaceae species grown in southern Brazil
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Vieira, Helena Cristina

; dos Santos, Joielan Xipaia

; Souza, Deivison Venicio

; Rios, Polliana D’ Angelo

; Bolzon de Muñiz, Graciela Inés

; Ribeiro Morrone, Simone

; Nisgoski, Silvana

Maderas. Ciencia y tecnología

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2022, Volumen 24 elocation 16

Resumen: En | Texto: En | PDF: En

Abstract: Because of the need for identification of forest species, especially for detection of illegal wood trade, the objective of this study was to evaluate the potential of colorimetry for differentiation of Inga vera Willd., Muellera campestris (Mart. ex Benth.) M.J. Silva & A.M.G. Azevedo and Machaerium paraguariense Hassl., species of the Fabaceae family, native to the Araucaria Forest in the state of Santa Catarina, southern Brazil. Discs at breast height were collected from three trees of each species and the colorimetric parameters (L*, a*, b*, C* and h) and visible spectra were evaluated in different radial position of the trunk (near bark, intermediate and near pith) and three different anatomical sections (transversal, radial and tangential surfaces). Mean values of hue angle (h) among the colorimetric parameters resulted in the highest potential for species discrimination. With respect to radial trunk position and anatomical section, parameters a* (green-red) and h were not statistically different, independent of the wood samples evaluated. For other parameters (L*, b* and C*), each species presented distinct results. Principal component analysis with second derivative of visible spectra discriminated all species. Colorimetry associated with chemometrics allowed to distinguish I. vera, M. campestris and M. paraguariense.

https://doi.org/10.4067/s0718-221x2022000100416 68 descargas

13.

Official position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry: part I (technical aspects)— general concepts, indications, acquisition, and analysis
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Maeda, Sergio Setsuo

; Peters, Barbara Santarosa Emo

; Martini, Lígia Araújo

; Antunes, Hannah Karen Moreira

; Gonzalez, Maria Cristina

; Arantes, Henrique Pierotti

; Prado, Carla M.

; Pinto, Camila Lemos

; Araújo, Iana Mizumukai de

; Paula, Francisco José Albuquerque de

; Borges, Joao Lindolfo Cunha

; Albergaria, Ben-Hur

; Ushida, Marcela

; Souza, Guilherme Cardenaz de

; Mendonça, Laura Maria Carvalho de

; Prado, Mirley do

; Pinheiro, Marcelo de Medeiros

Advances in Rheumatology

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2022, Volumen 62 elocation 7

Resumen: En | Texto: En | PDF: En

Abstract Objective: To review the technical aspects of body composition assessment by dual-energy X-ray absorptiometry (DXA) and other methods based on the most recent scientific evidence. Materials and methods: This Official Position is a result of efforts by the Scientific Committee of the Brazilian Association of Bone Assessment and Metabolism (Associação Brasileira de Avaliação Óssea e Osteometabolismo, ABRASSO) and health care professionals with expertise in body composition assessment who were invited to contribute to the preparation of this document. The authors searched current databases for relevant publications. In this first part of the Official Position, the authors discuss the different methods and parameters used for body composition assessment, general principles of DXA, and aspects of the acquisition and analysis of DXA scans. Conclusion: Considering aspects of accuracy, precision, cost, duration, and ability to evaluate all three compartments, DXA is considered the gold-standard method for body composition assessment, particularly for the evaluation of fat mass. In order to ensure reliable, adequate, and reproducible DXA reports, great attention is required regarding quality control procedures, preparation, removal of external artifacts, imaging acquisition, and data analysis and interpretation.

https://doi.org/10.1186/s42358-022-00241-8

14.

Official Position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry—part II (clinical aspects): interpretation, reporting, and special situations
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Maeda, Sergio Setsuo

; Albergaria, Ben-Hur

; Szejnfeld, Vera Lúcia

; Lazaretti-Castro, Marise

; Arantes, Henrique Pierotti

; Ushida, Marcela

; Domiciano, Diogo Souza

; Pereira, Rosa Maria Rodrigues

; Marin-Mio, Rosângela Villa

; Oliveira, Mônica Longo de

; Mendonça, Laura Maria Carvalho de

; Prado, Mirley do

; Souza, Guilherme Cardenaz de

; Palchetti, Cecília Zanin

; Sarni, Roseli Oselka Saccardo

; Terreri, Maria Teresa

; Castro, Luiz Claudio Gonçalves de

; Artoni, Silvana Martinez Baraldi

; Amoroso, Lizandra

; Karcher, Débora Emy

; Prado, Carla M.

; Gonzalez, Maria Cristina

; Pinheiro, Marcelo de Medeiros

Advances in Rheumatology

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2022, Volumen 62 elocation 11

Resumen: En | Texto: En | PDF: En

Abstract Objective: To present an updated and evidence-based guideline for the use of dual-energy x-ray absorptiometry (DXA) to assess body composition in clinical practice. Materials and methods: This Official Position was developed by the Scientific Committee of the Brazilian Association of Bone Assessment and Metabolism ( Associação Brasileira de Avaliação Óssea e Osteometabolismo , ABRASSO) and experts in the field who were invited to contribute to the preparation of this document. The authors searched current databases for relevant publications in the area of body composition assessment. In this second part of the Official Position, the authors discuss the interpretation and reporting of body composition parameters assessed by DXA and the use of DXA for body composition evaluation in special situations, including evaluation of children, persons with HIV, and animals. Conclusion: This document offers recommendations for the use of DXA in body composition evaluation, including indications, interpretation, and applications, to serve as a guiding tool in clinical practice and research for health care professionals in Brazil.

https://doi.org/10.1186/s42358-022-00240-9

15.

Indirect ELISA as a complementary diagnostic method of bovine tuberculosis
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Souza, Mariana A.

; Bombonato, Nadia G.

; Dib, Cristina C.

; Lima, Anna M.C.

Pesquisa Veterinária Brasileira

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2022, Volumen 42 elocation e06981

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: A tuberculose bovina é um problema econômico mundial e de saúde, que requer métodos de diagnóstico precisos para controle e erradicação. Objetivou-se com este estudo avaliar o desempenho de um teste comercial de ELISA no diagnóstico da tuberculose bovina. Foram avaliados pelo teste cervical comparativo (TCC) 1644 bovinos, provenientes de oito rebanhos de exploração leiteira, sendo três deles sem histórico recente da doença, e outros cinco com resultados positivos no último exame de tuberculinização. Para o diagnóstico sorológico da tuberculose utilizou-se um kit comercial de ELISA Mycobacterium bovis antibody test (ELISA M. bovis). Amostras de soro sanguíneo de 846 bovinos provenientes dos mesmos rebanhos foram também avaliadas no ELISA M. bovis. Os bovinos positivos no TCC e/ou ELISA M. bovis foram encaminhados para o abate sanitário. Dos positivos no ELISA para M. bovis foi realizado o exame macroscópico das carcaças e classificação das mesmas em: com presença ou ausência de lesões. Amostras de pulmão, fígado, e linfonodos, foram colhidas em duplicata para realização dos exames de cultivo microbiológico com posterior confirmação por PCR, e exame histopatológico com coloração de hematoxilina e eosina (HE). Dos 1,644 bovinos, 61 foram considerados positivos e 65 inconclusivos no TCC. O reteste dos inconclusivos identificou mais 19 positivos. No total, 80 (4,8%) bovinos positivos no TCC, provenientes de 5 rebanhos foram encaminhados para abate. O ELISA para M. bovis identificou 4,2% (36/846) de bovinos positivos, sendo 36 considerados negativos e um inconclusivo no exame de tuberculinização. Dos positivos no ELISA para M. bovis, 27 foram eutanasiados, e no exame macroscópico das carcaças 11% (3/27) dos animais apresentaram lesões sugestivas de tuberculose, e em apenas dois houve confirmação da doença pelos métodos histológico, microbiológico e PCR. A baixa associação dos resultados obtidos no ELISA para M. bovis com os exames macroscópico, histológico e isolamento microbiológico apontam para a fragilidade do desempenho do ELISA para o diagnóstico de tuberculose. Sugere-se assim que seu uso como método complementar para saneamento de rebanhos, seja adotado com cautela e considere a situação epidemiológica local.

ABSTRACT: Bovine tuberculosis is an economic and health problem, requiring precise diagnostic methods for its control and eradication. The aim of this study was to evaluate the performance of a commercial enzyme-linked immunosorbent assay (ELISA) test for the diagnosis of bovine tuberculosis. A total of 1,644 cattle from eight dairy herds were evaluated using the comparative cervical tuberculin test (CCTT). Three of the herds had no recent tuberculosis infection, and the other five had shown positive results in a previous tuberculin test. For the serological diagnosis of tuberculosis, a commercial ELISA antibody test kit for Mycobacterium bovis was used. Serum samples from 846 cattle from the eight herds were evaluated using ELISA for M. bovis. Animals that were positive based on either CCTT or ELISA for M. bovis or both were sent to slaughter. Samples of their lungs, livers, and lymph nodes were collected and stored under refrigeration for microbiological culture and subsequent confirmation by polymerase chain reaction. Samples from the same tissues were also fixed with 10% formaldehyde in bottles for histopathological examination and stained with hematoxylin and eosin (HE). Of the 1,644 cattle, 61 were considered positive and 65 inconclusive based on CCTT. Retesting of the inconclusive samples identified an additional 19 positive cases, totaling 80 (4.8%) CCTT-positive animals from five herds. ELISA for M. bovis identified 4.2% (36/846) positive cattle, of which 35 were considered negative and one inconclusive based on CCTT. Of the 36 positive cases identified by ELISA for M. bovis, 27 were euthanized, 11% (3/27) showed suggestive lesions of tuberculosis on macroscopic examination, and two were confirmed by histological, microbiological, and PCR methods. The weak association of ELISA for M. bovis with the results obtained by macroscopic, histological, and microbiological isolation indicates the fragility of ELISA performance in field conditions. Therefore, it is suggested that its use as a complementary method for herd sanitation be based on the local epidemiological situation.

https://doi.org/10.1590/1678-5150-pvb-6981

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