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1.
Post-discharge all-cause mortality in COVID-19 recovered patients hospitalized in 2020: the impact of chronic kidney disease
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Lomba, Guilherme Schittine Bezerra
; Silva, Pedro Henrique Abreu da
; Rosário, Natalia Fonseca do
; Medeiros, Thalia
; Alves, Lilian Santos
; Silva, Andrea Alice
; Almeida, Jorge Reis
; Lugon, Jocemir Ronaldo
.
ABSTRACT In Brazil, the COVID-19 burden was substantial, and risk factors associated with higher in-hospital mortality rates have been extensively studied. However, information on short-term all-cause mortality and the factors associated with death in patients who survived the hospitalization period of acute SARS-CoV-2 infection is limited. We analyzed the six-month post-hospitalization mortality rate and possible risk factors of COVID-19 patients in a single center in Brazil. This is a retrospective cohort study focused on a six-month follow-up. The exclusion criteria were death during hospitalization, transference to another hospital, and age under 18. We collected data from the charts of all hospitalized patients from March 2020 to December 2020 with a positive RT-PCR test for SARS-CoV-2, resulting in a sample size of 106 patients. The main outcome was death after hospitalization, whereas comorbidities and demographics were evaluated as risk factors. The crude post-hospitalization death rate was 16%. The first 30 days of follow-up had the highest mortality rate. In a Cox regression model for post-hospitalization mortality, previous chronic kidney disease (HR, 4.06, 95%CI 1.46 – 11.30) and longer hospital stay (HR 1.01, 95%CI 1.00 – 1.02) were the only factors statistically associated with death. In conclusion, a high six-month all-cause mortality was observed. Within the six-month follow-up, a higher risk of death was observed for patients who had prior CKD and longer hospital stay. These findings highlight the importance of more intensive medical surveillance during this period.
2.
Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023
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Teixeira, Ricardo Alkmim
; Fagundes, Alexsandro Alves
; Baggio Junior, José Mário
; Oliveira, Júlio César de
; Medeiros, Paulo de Tarso Jorge
; Valdigem, Bruno Pereira
; Teno, Luiz Antônio Castilho
; Silva, Rodrigo Tavares
; Melo, Celso Salgado de
; Elias Neto, Jorge
; Moraes Júnior, Antonio Vitor
; Pedrosa, Anisio Alexandre Andrade
; Porto, Fernando Mello
; Brito Júnior, Hélio Lima de
; Souza, Thiago Gonçalves Schroder e
; Mateos, José Carlos Pachón
; Moraes, Luis Gustavo Belo de
; Forno, Alexander Romeno Janner Dal
; D’Avila, Andre Luiz Buchele
; Cavaco, Diogo Alberto de Magalhães
; Kuniyoshi, Ricardo Ryoshim
; Pimentel, Mauricio
; Camanho, Luiz Eduardo Montenegro
; Saad, Eduardo Benchimol
; Zimerman, Leandro Ioschpe
; Oliveira, Eduardo Bartholomay
; Scanavacca, Mauricio Ibrahim
; Martinelli Filho, Martino
; Lima, Carlos Eduardo Batista de
; Peixoto, Giselle de Lima
; Darrieux, Francisco Carlos da Costa
; Duarte, Jussara de Oliveira Pinheiro
; Galvão Filho, Silas dos Santos
; Costa, Eduardo Rodrigues Bento
; Mateo, Enrique Indalécio Pachón
; Melo, Sissy Lara De
; Rodrigues, Thiago da Rocha
; Rocha, Eduardo Arrais
; Hachul, Denise Tessariol
; Lorga Filho, Adalberto Menezes
; Nishioka, Silvana Angelina D’Orio
; Gadelha, Eduardo Barreto
; Costa, Roberto
; Andrade, Veridiana Silva de
; Torres, Gustavo Gomes
; Oliveira Neto, Nestor Rodrigues de
; Lucchese, Fernando Antonio
; Murad, Henrique
; Wanderley Neto, José
; Brofman, Paulo Roberto Slud
; Almeida, Rui M. S.
; Leal, João Carlos Ferreira
.
3.
Timeline analysis of IgA and IgG levels in Covid-19 hospitalized patients according to the clinical outcome
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Medeiros, Thalia
; Carvalho, Fabiana R.
; Faustino, Renan
; Guimarães, Gabriel M. C.
; Alves, Lilian S.
; Oliveira, Any Caroline
; Azeredo, Elzinandes L.
; Almeida, Jorge R.
; Pinto, Luzia Maria O.
; Silva, Andrea Alice
.
Jornal Brasileiro de Patologia e Medicina Laboratorial
- Journal Metrics
RESUMO Introdução: Estudos sugerem a associação entre a produção de anticorpos e a gravidade da coronavirus disease 2019 (Covid-19). Objetivos: Avaliar as concentrações de imunoglobulinas da classe A (IgA) e da classe G (IgG) durante a internação de pacientes com Covid-19 de acordo com o desfecho (sobrevida vs óbito). Materiais e métodos: Pacientes com infecção pela síndrome respiratória aguda grave do coronavírus 2 (Sars-CoV-2) confirmada por reação da transcriptase reversa seguida de reação em cadeia da polimerase (RT-PCR) foram incluídos neste estudo prospectivo. As amostras foram obtidas semanalmente durante o acompanhamento dos indivíduos, considerando o início dos sintomas. Os títulos de IgA e IgG anti-Sars-CoV-2 foram mensurados por meio de um imunoensaio comercial. Correlações entre IgA/IgG e valores de limiar de detecção [cycle thresholds (Ct)] para os genes alvos N1 e N2 também foram avaliadas. Resultados: Estudamos 55 pacientes com Covid-19 (59,7 ± 6,2 anos; 63,6% do sexo masculino); destes, 28 (50,9%) morreram. Observamos positividade para IgA e IgG (IgA+/IgG+) em 90,9% e 80% dos pacientes, respectivamente. A maior frequência de IgA+ foi verificada nas semanas 2 e 3, e a maior frequência de IgG+, nas semanas 3 e 4. É importante observar que os pacientes que morreram apresentaram títulos de IgA mais baixos nas primeiras duas semanas (p < 0,05); no entanto, um aumento significativo na concentração de IgA foi observado nas semanas subsequentes. Por fim, identificamos correlações significativas entre os valores de Ct e imunoglobulinas; tanto IgA quanto IgG foram correlacionadas com Ct N2 em pacientes que morreram. Conclusão: Nossos resultados sugerem que títulos mais baixos de IgA no início da Covid-19 - que estão associados a valores mais baixos de Ct - podem indicar pacientes com risco elevado de evoluir para óbito.
ABSTRACT Introduction: Studies suggest the association between antibody production and the severity of coronavirus disease 2019 (Covid-19). Objectives: To evaluate the concentrations of immunoglobulins class A (IgA) and class G (IgG) during the hospitalization period of Covid-19 patients according to the outcome (survival vs death). Materials and methods: Patients with severe acute respiratory syndrome of coronavirus 2 (Sars-CoV-2) infection confirmed by reverse transcriptase reaction followed by polymerase chain reaction (RT-PCR) were included in this prospective study. Samples were obtained weekly during the follow-up of individuals, considering symptom onset. Titers of anti-Sars-CoV-2 IgA and IgG were measured using a commercial immunoassay. Correlations between IgA/IgG and cycle threshold (Ct) values for N1 and N2 target genes were also assessed. Results: We studied 55 Covid-19 patients (59.7±16.2 years, 63.6% male), of which 28 (50.9%) died. We observed IgA and IgG positivity (IgA+ and IgG+) in 90.9% and 80% of patients, respectively. The highest IgA+ frequency was observed at weeks 2 and 3 and the highest IgG+ at weeks 3 and 4. It is important to note that patients who died presented lower IgA titers in the first two weeks (p < 0.05); however, a significant increase in IgA levels was observed in the subsequent weeks. Lastly, we identified that significant correlations between Ct values and immunoglobulins levels, both IgA and IgG were correlated with Ct N2 in patients who died. Conclusion: Our results suggest that lower IgA titers in early Covid-19, which is associated with lower Ct values, may indicate patients at higher risk for death.
RESUMEN Introducción: Los estudios sugieren una asociación entre la producción de anticuerpos y la gravedad de la enfermedad por coronavirus 2019 (Covid-19). Objetivos: Evaluar las concentraciones de inmunoglobulinas clase A (IgA) y clase G (IgG) durante la hospitalización de pacientes con Covid-19 según el desenlace (supervivencia vs muerte). Materiales y métodos: Se incluyeron en este estudio prospectivo pacientes con síndrome respiratorio agudo severo de infección por coronavirus 2 (Sars-CoV-2) confirmado por la reacción en cadena de la polimerasa con transcriptasa inversa (RT-PCR). Las muestras se obtuvieron semanalmente durante el seguimiento de los individuos, considerando la aparición de los síntomas. Los títulos de IgA e IgG anti-Sars-CoV-2 se midieron usando un inmunoensayo comercial. También se evaluaron las correlaciones entre IgA/IgG y los valores de los umbrales de ciclo [cycle threshold (Ct)] para los genes N1 y N2. Resultados: Se estudiaron 55 pacientes Covid-19 (59,7 ± 16,2 años, 63,6% varones), de los cuales 28 (50,9%) fallecieron. Observamos positividad de IgA e IgG (IgA+ e IgG+) en el 90,9% y el 80% de los pacientes, respectivamente. La frecuencia más alta de IgA+ se observó en las semanas dos y tres y la IgG + más alta en las semanas tres y cuatro. Es importante señalar que los pacientes que fallecieron presentaron títulos de IgA más bajos en las dos primeras semanas (p < 0,05); sin embargo, se observó un aumento significativo en los niveles de IgA en las semanas siguientes. Conclusión: Identificamos correlaciones significativas entre los valores de Ct y los niveles de Ig, tanto IgA como IgG se correlacionaron con Ct N2 en los pacientes que fallecieron. Nuestros resultados sugieren que los títulos de IgA más bajos en Covid-19 temprano, que se asocia con valores de Ct más bajos, pueden indicar que los pacientes tienen un mayor riesgo de muerte.
https://doi.org/10.5935/1676-2444.20210021
231 downloads
4.
A Medicina Interna do Centro Hospitalar Universitário S. João na Pandemia COVID-19
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5.
Fuzzy modeling of the risk of cacao moniliasis occurrence in Bahia state, Brazil
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Almeida, Samira L. H. de
; Silva, Samuel de A.
; Lima, Julião S. de S.
; Rosas, Jorge T. F.
; Capelini, Vinicius A.
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO Com este trabalho objetivou-se definir áreas potenciais de estabelecimento da monilíase do cacaueiro no Estado da Bahia, por meio da lógica fuzzy, com base em séries históricas de temperatura e umidade relativa do ar, disponíveis para 519 pontos de medição distribuídos no Estado da Bahia. Os dados foram submetidos inicialmente a uma análise estatística descritiva. A variabilidade espacial foi determinada através de análise geoestatística, seguida de interpolações para mapear a estrutura da dependência espaço-temporal do fenômeno. Para modelar o risco climático de estabelecimento da doença foram realizadas simulações de classificação contínua, pixel-a-pixel, das representações das variáveis, utilizando o mapeamento fuzzy. Aos dados de temperatura, aplicou-se o modelo fuzzy exponencial, enquanto que aos dados de umidade relativa do ar, o modelo utilizado foi o linear. As definições de áreas potenciais foram realizadas para cada mês, utilizando a informação conjunta das pertinências da temperatura e da umidade relativa do ar. Os modelos fuzzy utilizados permitiram modelar o risco climático de estabelecimento da monilíase no Estado da Bahia. A maior extensão do Estado da Bahia tem riscos elevados para o desenvolvimento da doença, o que exige medidas mitigadoras para evitar a introdução e disseminação do patógeno.
ABSTRACT This work aimed to determine potential areas for the establishment of cocoa moniliasis in Bahia state, Brazil, by means of fuzzy logic, based on historical datasets of temperature and air relative humidity, available for 519 measurement points distributed throughout the state of Bahia. The data were initially submitted to a descriptive statistical analysis. The spatial variability was determined through geostatistical analysis, followed by interpolation to map the spatial-temporal structure dependence of the phenomenon. Simulations of continuous pixel-to-pixel classification of variables were performed using fuzzy mapping to model the climatic risk of disease establishment. The exponential fuzzy model was applied to temperature data, while the linear model was used for air relative humidity data. The potential areas were defined for each month, using data of temperature and air relative humidity. The fuzzy models used allowed for modeling of the climatic risk of cocoa moniliasis establishment. A large area of the state is at high risk of disease, thus requiring mitigating measures to avoid the pathogen’s introduction and dissemination.
https://doi.org/10.1590/1807-1929/agriambi.v24n4p225-230
716 downloads
6.
Exploring the metallochromic behavior of pentacyanidoferrates in visual, electronic and Raman spot tests
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Abstract: Pentacyanidoferrate(II) complexes of aromatic N-heterocycles, such as 4-cyanopyridine, exhibit characteristic colors and strong metallochromism associated with the donor-acceptor interactions of the metal ions with the cyanide ligands. In the presence of transition metal ions insoluble polymeric complexes are formed, displaying bright yellow, red, brown and green colors with zinc(II), nickel(II), copper(II) and iron(III) ions, respectively. Such metallochromic response is better observed on filter paper, allowing applications in analytical spot tests. The effects can be explored visually and probed by means of modern instrumental facilities, including spectrophotometric and resonance Raman techniques. In this way, by using the cyanopyridinepentacyanidoferrates, the Prussian Blue test for ferric ions can be extended to the entire row of transition metal elements, providing a new and modern insight of such classical Feigl’s spot tests.
https://doi.org/10.1590/0001-3765201920180315
1491 downloads
7.
Soil physical properties and yield of soybean and corn grown with wastewater
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Almeida, Alexsandro C. dos S.
; Santos, Higor H. O.
; Bortolo, Dhiego P.
; Lourente, Elaine R. P.
; Cortez, Jorge W.
; Oliveira, Fabricio C. de
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO Objetivou-se avaliar as produtividades de soja, milho e os atributos físicos de um Latossolo Vermelho Distroférrico fertilizado com água residuária de suinocultura (ARS). Para isso, foi realizado um experimento a campo utilizando o delineamento em blocos casualizados. Foram avaliados cinco tratamentos de adubação na safra 2014/2015 (soja no verão e milho segunda safra). Os tratamentos foram: T1 - Controle (fertilizado exclusivamente com adubação química); T2 - Fertilizado com 1270 m3 ha-1 de ARS; T3 - fertilizado com 170 m3 ha-1 de ARS; T4 - Fertilizado com 50 m3 ha-1 de ARS; e, T5 - Fertilizado com 50 m3 ha-1 de ARS mais adubação química. Amostragens e análises físicas de solo foram realizadas antes do cultivo da soja e após a colheita do milho. Em relação aos atributos físicos do solo, não houve alterações significativas durante o período avaliado. A aplicação de água residuária de suinocultura na fertilização dos cultivos de soja e milho, cultivadas num solo Latossolo Vermelho Distroférrico com alto teor de argila, influenciaram positivamente esses cultivos, uma vez que proporcionou boas produtividades para soja (com média de 2990,85 kg ha-1) e incremento de produtividade para o milho (com máxima de 7126,5 kg ha-1). Além disso, os atributos físicos do solo não foram alterados.
ABSTRACT This study aimed to evaluate soybean and corn yields and soil physical attributes of a Dystrophic Red Latosol fertilized with swine wastewater (SW). Therefore, a field experiment was conducted in randomized blocks to evaluate five treatments of fertilization in the 2014/2015 season (soybean in the summer and corn in the second season). The treatments were: T1 - control (fertilized exclusively with chemical fertilizers); T2 - fertilized with 1270 m3 ha-1 of SW; T3 - fertilized with 170 m3 ha-1 of SW; T4 - fertilized with 50 m3 ha-1 of SW; and T5 - fertilized with 50 m3 ha-1 of SW + chemical fertilization. Soil samplings and soil physical analyses were performed before soybean cultivation and after corn harvest. No significant alteration was observed in soil physical attributes during the evaluation period. The application of swine wastewater in the fertilization of soybean and corn, cultivated in Dystrophic Red Latosol with high clay contents, positively affected these crops, since it led to good yields in soybean (with an average of 2990.85 kg ha-1) and increased corn yields (with a maximum of 7126.5 kg ha-1). In addition, soil physical properties were not altered.
8.
Agronomic and molecular characterization of wild germplasm Saccharum spontaneum for sugarcane and energycane breeding purposes
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Silva, Jorge Alberto Gonçalves da
; Costa, Paulo Mafra de Almeida
; Marconi, Thiago Gibbin
; Barreto, Everton Jean da Silva
; Solís-Gracia, Nora
; Park, Jon-Won
; Glynn, Neil Charles
.
ABSTRACT: Among the species related to sugarcane, Saccharum spontaneum (L.) is a wild species with the greatest potential as a source of genetic variation to cope with biomass production in harsh environments. Due to its high yield, early vigor, ratooning ability, low input requirements and tolerance to various biotic and abiotic stresses, sugarcane breeders have shown interest in its contribution, as a donor of genes, to the development of high biomass energy canes. The conservation, evaluation and utilization of the genetic variability of S. spontaneum available in germplasm collections are critical for breeding, but, given the aggressive rhizomatous growth habit and the ability to propagate via seed dispersal, S. spontaneum is classified as a noxious weed in several nations, including the U.S.A. As a result, field trials are restrictive and few phenotypic analyses have been carried out on these collections. In the present study, a subset of 130 S. spontaneum accessions obtained from the World Collection of Sugarcane and Related Grasses in Miami, FL has been characterized phenotypically - with either morphological and agronomic traits (including composition analysis) or reaction to abiotic stress and genotypically - molecular markers (Simple Sequence Repeats - SSR). Using these data, a core collection has been established, genotypes with positive agronomic traits have been identified and are being used as parents for hybridization crosses, aimed at genetic improvement of sugarcane and energycane.
https://doi.org/10.1590/1678-992x-2017-0028
1697 downloads
9.
Brazilian legislation on genetic heritage harms Biodiversity Convention goals and threatens basic biology research and education
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ALVES, RUY JOSÉ V.
; WEKSLER, MARCELO
; OLIVEIRA, JOÃO A.
; BUCKUP, PAULO A.
; POMBAL JR., JOSÉ P.
; SANTANA, HÉLCIO R.G.
; PERACCHI, ADRIANO LÚCIO
; KELLNER, ALEXANDER W.A.
; ALEIXO, ALEXANDRE
; LANGGUTH, ALFREDO
; ALMEIDA, ALZIRA MARIA P. DE
; ALBERNAZ, ANA LUISA
; RIBAS, CAMILA C.
; ZILBERBERG, CARLA
; GRELLE, CARLOS EDUARDO V.
; ROCHA, CARLOS F.D.
; LAMAS, CARLOS JOSÉ E.
; HADDAD, CÉLIO F.B.
; BONVICINO, CIBELE R.
; PRADO, CYNTHIA P.A.
; LIMA, DANIELA O. DE
; ROSSA-FERES, DENISE C.
; SANTOS, FABRÍCIO R. DOS
; SALIMENA, FÁTIMA REGINA G.
; PERINI, FERNANDO A.
; BOCKMANN, FLÁVIO A.
; FRANCO, FRANCISCO LUÍS
; GIUDICE, GISELE M.L. DEL
; COLLI, GUARINO R.
; VIEIRA, IMA CÉLIA G.
; MARINHO-FILHO, JADER
; WERNECK, JANE M.C.F.
; SANTOS, JORGE A.D. DOS
; NASCIMENTO, JORGE LUIZ DO
; NESSIMIAN, JORGE LUIZ
; CORDEIRO, JOSÉ LUIS P.
; CLARO, KLEBER DEL
; SALLES, LEANDRO O.
; CASATTI, LILIAN
; PY-DANIEL, LUCIA HELENA R.
; SILVEIRA, LUÍS FÁBIO
; TOLEDO, LUÍS FELIPE
; OLIVEIRA, LUIZ F. DE
; MALABARBA, LUIZ ROBERTO
; SILVA, MARCELO D. DA
; COURI, MÁRCIA S.
; MARTINS, MÁRCIO
; TAVARES, MARCOS D.S.
; SOBRAL, MARCOS EDUARDO G.
; VIEIRA, MARCUS VINÍCIUS
; OLIVEIRA, MARIA DE LOURDES A.
; PINNA, MÁRIO DE
; HOPKINS, MICHAEL J.G.
; SOLÉ, MIRCO
; MENEZES, NAÉRCIO A.
; PASSOS, PAULO
; D’ANDREA, PAULO SERGIO
; PINTO, PEDRO C.E.A.
; VIANA, PEDRO L.
; TOLEDO, PETER M.
; REIS, ROBERTO E.
; VILELA, ROBERTO
; BASTOS, ROGÉRIO P.
; COLLEVATTI, ROSANE G.
; CERQUEIRA, RUI
; CASTROVIEJO-FISHER, SANTIAGO
; CARAMASCHI, ULISSES
.
https://doi.org/10.1590/0001-3765201820180460
7311 downloads
10.
A Medicina Interna do Centro Hospitalar S. João: Hoje e no Futuro
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https://doi.org/10.24950/rspmi/OpinionArticle/2017
872 downloads
11.
Community-acquired methicillin-resistant Staphylococcus aureus carrying SCCmec type IV and V isolated from healthy children attending public daycares in northeastern Brazil
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Carvalho, Suzi P. de
; Almeida, Jéssica B. de
; Andrade, Yasmin M.F.S.
; Silva, Lucas S.C. da
; Oliveira, Arianne C. de
; Nascimento, Flávia S.
; Campos, Guilherme B.
; Oliveira, Márcio V.
; Timenetsky, Jorge
; Marques, Lucas M.
.
Abstract Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) have increasingly been reported in healthy communities. This study aimed to assess the rate of S. aureus in general and MRSA in particular from nasal secretion of children in daycare centers in Vitória da Conquista, Brazil. The isolates were identified based on morphology, biochemical tests and by PCR. Detection of virulence genes, biofilm production, and susceptibility test by disk diffusion agar were performed. MRSA isolates were characterized by spa, SCCmec, and multilocus sequence typing (MLST). S. aureus were recovered from 70 (47.3%) of 148 children. Among the 11 MRSA strains (15.7%), two SCCmec types (IV and V) were detected. MLST identified four STs related to three clonal complexes (CC): 5, 45, and 398. Four spa types were found circulating in this setting. Resistance of S. aureus isolates to ampicillin, erythromycin, ciprofloxacin, clindamycin, and tetracycline was 80%, 32.8%, 7.1%, 7.1% and 4.3%, respectively. One isolate presented intermediate resistance to vancomycin detected by Etest methodology. All strains were biofilm producers. The virulence genes seb, sec, spa, and pvl were detected in some isolates. This study revealed a high rate of children carrying MRSA among healthy attendees in daycare centers in Vitória da Conquista, Brazil.
https://doi.org/10.1016/j.bjid.2017.04.001
945 downloads
12.
Porcine circovirus 2 (PCV2) increases the expression of endothelial adhesion/junction molecules
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Marks, Fernanda S.
; Almeida, Laura L.
; Driemeier, David
; Canal, Cláudio
; Barcellos, David E.S.N.
; Guimarães, Jorge A.
; Reck, José
.
Abstract Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus disease, a complex multisystem syndrome in domestic pigs. Despite the significant economic losses caused by porcine circovirus disease, the mechanisms of pathogenesis underlying the clinical findings remain largely unclear. As various reports have highlighted the potential key role of vascular lesions in the pathogenesis of porcine circovirus disease, the aim of this work was to investigate effects of PCV2 infection on vascular endothelial cells, focusing on cell viability and expression of adhesion/junction molecules. PCV2 infection reduced endothelial cell viability, while viral infection did not affected the viability of several other classical cell lines. Also, PCV2 infection in endothelial cells displayed a dual/biphasic effect: initially, infection increased ICAM-1 expression, which can favor leukocyte recruitment and emigration to tissues and possibly inducing characteristic porcine circovirus disease inflammatory lesions; then, secondarily, infection caused an increase in zonula occludens 1 tight junction protein (ZO-1) expression, which in turn can result in difficulties for cell traffic across the endothelium and a potential impairment the immune response in peripheral tissues. These virus-induced endothelial changes could directly impact the inflammatory process of porcine circovirus disease and associated vascular/immune system disturbances. Data suggest that, among the wide range of effects induced by PCV2 on the host, endothelial modulation can be a pivotal process which can help to explain PCV2 pathogenesis in some porcine circovirus disease presentations.
https://doi.org/10.1016/j.bjm.2016.07.001
884 downloads
13.
Heterogeneous methodology of racial/ethnic classification may be responsible for the different risk assessments for prostate cancer between Black and White men in Brazil
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Romero, Frederico R.
; Xavier, Luiz Ricardo T. P.
; Romero, Antonio W.
; Almeida, Rui Manuel S. de
; Matias, Jorge Eduardo F
; Tambara Filho, Renato
.
Objectives To evaluate if the different results of prostate cancer risk between black and white Brazilian men may be associated with the varying methodology used to define participants as either Blacks or Whites. Patients and Methods We evaluated median PSA values, rate of PSA level ≥4.0 ng/mL, indications for prostate biopsy, prostate cancer detection rate, biopsy/cancer rate, cancer/biopsy rate, and the relative risk of cancer between blacks versus whites, blacks versus non-blacks (browns and whites), non-whites (browns and blacks) versus whites, African versus non-African descendants, and African descendants or blacks versus non-African descendants and non-blacks. Results From 1544 participants, there were 51.4% whites, 37.2% browns, 11.4% blacks, and 5.4% African descendants. Median PSA level was 0.9 ng/mL in whites, browns, and non-African descendants, compared to 1.2 ng/mL in blacks, and African descendants or blacks, and 1.3 ng/mL in African descendants. Indications for prostate biopsy were present in 16.9% for African descendants, 15.9% of black, 12.3% of white, 11.4% for non-African descendants, and 9.9% of brown participants. Prostate cancer was diagnosed in 30.3% of performed biopsies: 6.2% of African descendants, 5.1% of blacks, 3.3% of whites, 3.0% of non-African descendants, and 2.6% of browns. Conclusions Median PSA values were higher for Blacks versus Whites in all classification systems, except for non-white versus white men. The rate of prostate biopsy, prostate cancer detection rate, and relative risk for cancer was increased in African descendants, and African descendants or blacks, compared to non-African descendants, and non-African descendants and non-blacks, respectively.
https://doi.org/10.1590/S1677-5538.IBJU.2015.02.25
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14.
Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
; Martins da Silva, Regina C.V.
; Martins, Ângela B.
; Martins, Erika R.
; Martins, Márcio L.L.
; Martins, Milena V.
; Martins, Renata C.
; Matias, Ligia Q.
; Maya-L., Carlos A.
; Mayo, Simon
; Mazine, Fiorella
; Medeiros, Debora
; Medeiros, Erika S.
; Medeiros, Herison
; Medeiros, João D.
; Meireles, José E.
; Mello-Silva, Renato
; Melo, Aline
; Melo, André L.
; Melo, Efigênia
; Melo, José I.M.
; Menezes, Cristine G.
; Menini Neto, Luiz
; Mentz, Lilian A.
; Mezzonato, A.C.
; Michelangeli, Fabián A.
; Milward-de-Azevedo, Michaele A.
; Miotto, Silvia T.S.
; Miranda, Vitor F.O.
; Mondin, Cláudio A.
; Monge, Marcelo
; Monteiro, Daniele
; Monteiro, Raquel F.
; Moraes, Marta D.
; Moraes, Pedro L.R.
; Mori, Scott A.
; Mota, Aline C.
; Mota, Nara F.O.
; Moura, Tania M.
; Mulgura, Maria
; Nakajima, Jimi N.
; Nardy, Camila
; Nascimento Júnior, José E.
; Noblick, Larry
; Nunes, Teonildes S.
; O'Leary, Nataly
; Oliveira, Arline S.
; Oliveira, Caetano T.
; Oliveira, Juliana A.
; Oliveira, Luciana S.D.
; Oliveira, Maria L.A.A.
; Oliveira, Regina C.
; Oliveira, Renata S.
; Oliveira, Reyjane P.
; Paixão-Souza, Bruno
; Parra, Lara R.
; Pasini, Eduardo
; Pastore, José F.B.
; Pastore, Mayara
; Paula-Souza, Juliana
; Pederneiras, Leandro C.
; Peixoto, Ariane L.
; Pelissari, Gisela
; Pellegrini, Marco O.O.
; Pennington, Toby
; Perdiz, Ricardo O.
; Pereira, Anna C.M.
; Pereira, Maria S.
; Pereira, Rodrigo A.S.
; Pessoa, Clenia
; Pessoa, Edlley M.
; Pessoa, Maria C.R.
; Pinto, Luiz J.S.
; Pinto, Rafael B.
; Pontes, Tiago A.
; Prance, Ghillean T.
; Proença, Carolyn
; Profice, Sheila R.
; Pscheidt, Allan C.
; Queiroz, George A.
; Queiroz, Rubens T.
; Quinet, Alexandre
; Rainer, Heimo
; Ramos, Eliana
; Rando, Juliana G.
; Rapini, Alessandro
; Reginato, Marcelo
; Reis, Ilka P.
; Reis, Priscila A.
; Ribeiro, André R.O.
; Ribeiro, José E.L.S.
; Riina, Ricarda
; Ritter, Mara R.
; Rivadavia, Fernando
; Rocha, Antônio E.S.
; Rocha, Maria J.R.
; Rodrigues, Izabella M.C.
; Rodrigues, Karina F.
; Rodrigues, Rodrigo S.
; Rodrigues, Rodrigo S.
; Rodrigues, Vinícius T.
; Rodrigues, William
; Romaniuc Neto, Sérgio
; Romão, Gerson O.
; Romero, Rosana
; Roque, Nádia
; Rosa, Patrícia
; Rossi, Lúcia
; Sá, Cyl F.C.
; Saavedra, Mariana M.
; Saka, Mariana
; Sakuragui, Cássia M.
; Salas, Roberto M.
; Sales, Margareth F.
; Salimena, Fatima R.G.
; Sampaio, Daniela
; Sancho, Gisela
; Sano, Paulo T.
; Santos, Alessandra
; Santos, Élide P.
; Santos, Juliana S.
; Santos, Marianna R.
; Santos-Gonçalves, Ana P.
; Santos-Silva, Fernanda
; São-Mateus, Wallace
; Saraiva, Deisy P.
; Saridakis, Dennis P.
; Sartori, Ângela L.B.
; Scalon, Viviane R.
; Schneider, Ângelo
; Sebastiani, Renata
; Secco, Ricardo S.
; Senna, Luisa
; Senna-Valle, Luci
; Shirasuna, Regina T.
; Silva Filho, Pedro J.S.
; Silva, Anádria S.
; Silva, Christian
; Silva, Genilson A.R.
; Silva, Gisele O.
; Silva, Márcia C.R.
; Silva, Marcos J.
; Silva, Marcos J.
; Silva, Otávio L.M.
; Silva, Rafaela A.P.
; Silva, Saura R.
; Silva, Tania R.S.
; Silva-Gonçalves, Kelly C.
; Silva-Luz, Cíntia L.
; Simão-Bianchini, Rosângela
; Simões, André O.
; Simpson, Beryl
; Siniscalchi, Carolina M.
; Siqueira Filho, José A.
; Siqueira, Carlos E.
; Siqueira, Josafá C.
; Smith, Nathan P.
; Snak, Cristiane
; Soares Neto, Raimundo L.
; Soares, Kelen P.
; Soares, Marcos V.B.
; Soares, Maria L.
; Soares, Polyana N.
; Sobral, Marcos
; Sodré, Rodolfo C.
; Somner, Genise V.
; Sothers, Cynthia A.
; Sousa, Danilo J.L.
; Souza, Elnatan B.
; Souza, Élvia R.
; Souza, Marcelo
; Souza, Maria L.D.R.
; Souza-Buturi, Fátima O.
; Spina, Andréa P.
; Stapf, María N.S.
; Stefano, Marina V.
; Stehmann, João R.
; Steinmann, Victor
; Takeuchi, Cátia
; Taylor, Charlotte M.
; Taylor, Nigel P.
; Teles, Aristônio M.
; Temponi, Lívia G.
; Terra-Araujo, Mário H.
; Thode, Veronica
; Thomas, W.Wayt
; Tissot-Squalli, Mara L.
; Torke, Benjamin M.
; Torres, Roseli B.
; Tozzi, Ana M.G.A.
; Trad, Rafaela J.
; Trevisan, Rafael
; Trovó, Marcelo
; Valls, José F.M.
; Vaz, Angela M.S.F.
; Versieux, Leonardo
; Viana, Pedro L.
; Vianna Filho, Marcelo D.M.
; Vieira, Ana O.S.
; Vieira, Diego D.
; Vignoli-Silva, Márcia
; Vilar, Thaisa
; Vinhos, Franklin
; Wallnöfer, Bruno
; Wanderley, Maria G.L.
; Wasshausen, Dieter
; Watanabe, Maurício T.C.
; Weigend, Maximilian
; Welker, Cassiano A.D.
; Woodgyer, Elizabeth
; Xifreda, Cecilia C.
; Yamamoto, Kikyo
; Zanin, Ana
; Zenni, Rafael D.
; Zickel, Carmem S
.
Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
33340 downloads
15.
A fast sonochemical method to prepare 1D and 3D nanostructures of bismuth sulfide
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Mesquita, Paulo R. R.
; Almeida, Jorge S.
; Teixeira, Leonardo S. G.
; Silva, Antônio F. da
; Silva, Luciana A.
.
Nesse trabalho, um método sonoquímico de síntese de nanoestruturas de sulfeto de bismuto em 1D e 3D foi desenvolvido e comparado com uma rota sintética empregando aquecimento sob refluxo. O método sonoquímico monstrou ser mais rápido e eficiente na obtenção de nanoestruturas com alta homogeneidade morfológica. A forma e qualidade dos nanocristais foram dependentes do tipo de solvente empregado na síntese. Superestruturas em 3D semelhantes a flores foram obtidas quando etileno glicol puro foi utilizado como solvente, enquanto estruturas em 1D na forma de nanobastões foram obtidas quando utilizada uma mistura de dimetilsulfóxido e etileno como solvente.
In this work, a sonochemical method to synthesize nanostructures of bismuth sulfide in 1D and 3D framework was developed and compared with a synthetic route with heating under reflux. The sonochemical method showed to be faster and more efficient than refluxing method to obtain nanostructures with high morphological homogeneity. Form and quality of the nanocrystals were dependent on the type of solvent employed in the synthesis procedure. 3D flower-like superstructures were obtained when ethylene glycol was used as solvent, while 1D nanorods were obtained when a mixture of dimethyl sulfoxide and ethylene glycol was used as solvent.
https://doi.org/10.5935/0103-5053.20130036
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