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Descending Thoracic Aorta as inflow for primary revascularization of aorto-iliac occlusive disease - review of the last 30 years
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Nunes, Celso

; Pereira, Ricardo V.

; Pedrosa, João O’neill

; Oliveira, Vânia

; Silva, Eduardo

; Baldaia, Leonor

; Silva, Miguel

; Anacleto, Gabriel

Angiologia e Cirurgia Vascular

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sep 2023, Volume 19 N. 3 Pages 178 - 182

Abstract: En | Text: En | PDF: En

Abstract Introduction: The descending thoracic aorta (DTA) has been used as inflow mostly as a secondary option for revascularization after either graft failure/infection or other intra-abdominal pathologies contraindicating a standard abdominal aortic approach. The objective of this review is to summarize current evidence on the use of this inflow site for revascularization procedures. Methods: A comprehensive electronic literature search was performed, using PubMed and Embase databases. All literature published in English in the last 30 years was considered. The main goal was to assess the feasibility and practicality of implementing this approach in cases of severe and complex aortoiliac lesions. Results: Our review comprised 11 articles. DTA has been used predominately as a secondary option. The 30-day mortality rate was 4% (9/222). Secondary graft patency at 5-years was generally high across all studies. The use of DTA as inflow has been shown to be a safe and effective option for aorto-iliac reconstruction. Conclusion: DTA can be used safely as an inflow for lower-limb revascularization and it remains an important tool in the vascular surgeon's armamentarium.

https://doi.org/10.48750/acv.551

Critical Success Factors of Six Sigma and Lean Manufacturing Projects
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Bribiescas Silva, Francisco

; Hernández Gómez, Jesús A.

; Poblano-Ojinaga, Eduardo Rafael

; Valles Chávez, Adán

; Noriega Morales, Salvador Anacleto

RIDE. Revista Iberoamericana para la Investigación y el Desarrollo Educativo

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jun 2023, Volume 13 N. 26 elocation e053

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen La literatura de factores de la eficiencia de proyectos se Manufactura Esbelta y Seis Sigma es extensa, incluye reportes de sus cuestionables resultados y se observa la falta de explicaciones razonables, objetivas ellos. En la búsqueda de los factores de los proyectos ME/SS la literatura no es concluyente. Por ello, el objetivo de este proyecto de investigación es determinar esos factores. Para ese propósito, se realizó una revisión de literatura, determinado una lista de 29 factores en 48 artículos, dicha lista se redujo a 21 por Meta-Análisis. Con los factores se construyó un cuestionario, con 4 constructos y 25 indicadores, mismo que se validó con las pruebas de KMO y Bartlett. El cuestionario se aplicó a una muestra de 225 ingenieros con experiencia en proyectos de ME/SS desarrollados en plantas industriales que operan tecnologías de alto nivel. La especificación del modelo estructural inicia con un Análisis Factorial Exploratorio con rotación oblicua y por el método de Componentes Principales con rotación Promax y se aplicaron varios indicadores para la evaluación empírica. Se determinaron los factores críticos del éxito de proyectos de ME/SS y se comprobó la bondad de los métodos de ecuaciones estructurales. Se presenta y discute el modelo estructural y sus componentes.

Abstract Literature is extensive regarding the increases of efficiency by Six Sigma and Lean Manufacturing (SS/LM) projects, including reports of questionable results and the lack of reasonable explanations about those cases. In the search of the factors influencing the success of the projects, the literature is inconclusive. Therefore, the objective of this work is to determine the factors influencing the success of those projects. For which, a literature review was carried out finding that 48 publications gave a list of 29 factors, which is reduced to 21 by a Meta-Analysis study. These factors are used for the development of a questionnaire with 4 constructs and 25 indicators, which is validated with KMO and Bartlett’s tests. To identify the factors used in the industrial practice and their contributions to success, the questionnaire was applied to a sample of 225 engineers with experience in Six Sigma and Lean Manufacturing projects working in high tech manufacturing companies. The specification of the structural model starts with an exploratory factorial analysis-oblique rotation and the method of Principal Axes with Promax rotation, afterward for the empirical evaluation several indexes were used. The critical success factors and the usefulness of SEM for these purposes were determined. The structural model and its components are presented in this paper.

Resumo A literatura sobre os fatores de eficiência do projeto Lean Manufacturing e Seis Sigma é extensa, inclui relatórios de seus resultados questionáveis e carece de explicações razoáveis e objetivas para eles. Na busca dos fatores dos projetos ME/SS, a literatura não é conclusiva. Portanto, o objetivo deste projeto de pesquisa é determinar esses fatores. Para tanto, foi realizada uma revisão da literatura, determinando uma lista de 29 fatores em 48 artigos, esta lista foi reduzida para 21 por Meta-Análise. Foi construído um questionário com os fatores, com 4 construtos e 25 indicadores, o qual foi validado com os testes KMO e Bartlett. O questionário foi aplicado a uma amostra de 225 engenheiros com experiência em projetos de ME/SS desenvolvidos em plantas industriais que operam tecnologias de alto nível. A especificação do modelo estrutural inicia-se com uma Análise Exploratória de Fatores com rotação oblíqua e pelo método de Componentes Principais com rotação Promax e vários indicadores foram aplicados para avaliação empírica. Foram determinados os fatores críticos para o sucesso de projetos de ME/SS e verificada a qualidade dos métodos de equações estruturais. O modelo estrutural e seus componentes são apresentados e discutidos.

https://doi.org/10.23913/ride.v13i26.1497

VI Brazilian consensus guidelines for detection of anti-cell autoantibodies on HEp-2 cells
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Cruvinel, Wilson de Melo

; Andrade, Luis Eduardo Coelho

; Dellavance, Alessandra

; Ximenes, Antônio Carlos

; Bichara, Carlos David Araújo

; Mangueira, Cristóvão Luis Pitangueira

; Bonfá, Eloísa

; Brito, Fabiano de Almeida

; Mariz, Henrique Ataíde

; Anjos, Lisiane Maria Enriconi dos

; Pasoto, Sandra Gofinet

; Valim, Valeria

; Santos, Wilton Ferreira Silva dos

; Gomes, Clayson Moura

; Neves, Roberpaulo Anacleto

; Francescantonio, Paulo Luiz Carvalho

Advances in Rheumatology

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2022, Volume 62 elocation 34

Abstract: En | Text: En | PDF: En

Abstract Background: The VI Brazilian Consensus on Autoantibodies against HEp-2 cells for determination of autoantibodies against cellular constituents on HEp-2 cells was held on September, 2019, in Fortaleza (CE, Brazil). The guidelines in this edition were formulated by the group of Brazilian experts discussing the classification of complex patterns, the classification of the nuclear discrete dots (few and multiple), the identification of the discrete fine speckled pattern (AC-4a) and improvements on the ANA report. Mainbody: Sixteen Brazilian researchers and experts from universities and clinical laboratories representing the various geographical regions of Brazil participated in the meeting. Four main topics were discussed: (1) How to classify patterns with fluorescence in more than one cell compartment considering three relevant categoris: composite patterns, mixed patterns and multiple patterns; (2) The splitting of the discrete nuclear dots pattern into the multiple discrete nuclear dots (AC-6) and few discrete nuclear dots (AC-7) patterns, respectively; (3) Inclusion of a novel nuclear pattern characterized by discrete fine speckled pattern highly associated with antibodies to SS-A/Ro60, classified as AC-4a. In addition, adjustments on the Brazilian Consensus nomenclature were implemented aiming to harmonize the designation of some patterns with the International Consensus on ANA Patterns (ICAP). Furthermore, the designations of the PCNA-like pattern (AC-13), CENP-F-like pattern (AC-14) and Topo I-like pattern (AC-29) were adjusted in accordance to ICAP. Finally, there was a recommendation for adjustment in the test report in order to address the status of nuclear envelope staining. For all topics, the aim was to establish specific guidelines for laboratories and clinicians. All recommendations were based on consensus among participants. All recommendations from the V Consensus were maintained and there was relevant progress in the BCA/HEp-2 guidelines and further harmonization with ICAP. Conclusion: The VI BCA/HEp-2 edition was successful in establishing important recommendations regarding the classification of complex patterns, in supporting the identification of a novel pattern within the AC-4 group and in the harmonization process with the ICAP terminology.

https://doi.org/10.1186/s42358-022-00266-z

Teleoncology Orientation of Low-Income Breast Cancer Patients during the COVID-19 Pandemic: Feasibility and Patient Satisfaction
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Miziara, Roberta Amparado

; Maesaka, Jonathan Yugo

; Matsumoto, Danielle Ramos Martin

; Penteado, Laura

; Anacleto, Ariane Andrade dos Santos

; Accorsi, Tarso Augusto Duenhas

; Lima, Karine De Amicis

; Cordioli, Eduardo

; D´Alessandro, Gabriel Salum

Revista Brasileira de Ginecologia e Obstetrícia

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nov 2021, Volume 43 N. 11 Pages 840 - 846

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo O presente estudo teve como objetivo avaliar a viabilidade e satisfação em relação à orientação teleoncológica realizada em população vulnerável de pacientes com câncer de mama e provenientes do sistema público de saúde durante a pandemia do coronavírus em 2020. Métodos Pacientes elegíveis foram agendados para atendimento remoto visando minimizar exposição a ambientes com risco de infecção respiratória. O meio de comunicação foi o telefone, pois permite conversa sem custos. Um questionário anônimo com base na escala Likert foi enviado através de aplicativo de telefone celular ou e-mail para paciente ou familiares, logo após a teleconsulta. As respostas, que abordavam utilidade, facilidade, qualidade da interface, qualidade da interação, confiabilidade, satisfação e interesse em avaliações futuras, foram compiladas e analisadas. Resultados Um total de 176 pacientes elegíveis para teleconsulta foram avaliados e 98 foram incluídos. Setenta (71,4%) realizaram a teleorientação com sucesso. O questionário foi respondido por 43 (61,4%) pacientes. De maneira geral, a teleorientação foi classificada como muito positiva por 41 (95,3%) pacientes. Em relação aos itens avaliados, 43 (100%) pacientes pontuaram 4 ou 5 (concordaram que a teleconsulta era benéfica) em relação à facilidade do serviço, seguido por 42 (97,2%) para a qualidade da interface, 41 (95,3%) tanto para a utilidade quanto para a qualidade da interação, 40 (93%) para satisfação e interesse em avaliação futura e 39 (90,6%) para confiabilidade em relação ao método. Conclusão A orientação teleoncológica empacientes de baixa renda e com câncer de mama mostrou ser viável e com altas taxas de satisfação.

Abstract Objective The present study aims to assess the feasibility and patient satisfaction of teleoncology orientation in a vulnerable population of breast cancer patients assessed in a government health system during the coronavirus pandemic in 2020. Methods Eligible patients received an invitation to receive remote care to minimize exposure to an environment in which the risk of respiratory infection was present. The means of communication was telephone through an application that allows free conversation with no charge. An anonymous-response questionnaire based on a Likert-type scale was sent through a cell phone application or e-mail directly to each patient or close relative of the patient immediately after teleconsultation. Responses to the questions, which addressed utility, facility, interface quality, interaction quality, reliability, satisfaction, and interest in future evaluation, were compiled and analyzed. Results A total of 176 eligible patients scheduled for consultation were evaluated and 98 were included. Seventy (71.4%) successfully undertook the teleorientation. The questionnaire was submitted by 43 (61.4%) patients. The overall teleoncology orientation was classified as very positive by 41 (95.3%) patients. Specifically, regarding the questionnaire items, 43 (100%) patients scored 4 or 5 (agreed that the teleconsultation was beneficial) concerning the facility, followed by 42 (97.2%) for the interface quality, 41 (95.3%) for both utility and interaction quality, 40 (93%) for satisfaction and interest in future evaluation, and, finally, 39 (90.6%) for reliability. Conclusion Teleoncology orientation of low-income breast cancer patients is most feasible and leads to high patient satisfaction.

https://doi.org/10.1055/s-0041-1739425

Planificación urbana y la influencia de las urbanizaciones cerradas: El Área Metropolitana de Guadalajara, México
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Pfannenstein, Bernd

; Martínez Jaramillo, Jonatán Obed

; Anacleto Herrera, Edgar Eduardo

; Sevilla Villalobos, Salvador

Economía, sociedad y territorio

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apr 2019, Volume 19 N. 59 Pages 1087 - 1117

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Due to deficient urban planning, the Guadalajara Metropolitan Area has gone through a series of processes that finally resulted in a transformation where the phenomenon of gated urbanizations is of significant relevance. In particular, the conditions that the real estate sector found in this city allowed it to position itself as a main protagonist in the production of gated residential areas with restricted access. In the year 2016, the metropolis reached the total amount of 2973 gated communities. This phenomenon and its evolution require a discussion about how to rededicate public and urban spaces for collective use.

Resumen El Área Metropolitana de Guadalajara ha pasado por una serie de procesos que la llevaron a convertirse en una metrópolis, donde el fenómeno de las urbanizaciones cerradas tomó relevancia significativa, lo cual implica un resultado directo de la falta de planeación urbana. Las facilidades que encontró el sector inmobiliario le permitieron posicionarse como principal actor en el proceso de construcción urbana, logrando que en el 2016 la ciudad contara con 2 973 fraccionamientos de acceso restringido. Es un fenómeno que requiere la reinterpretación del espacio público de la ciudad y de sus espacios de uso colectivo.

https://doi.org/10.22136/est20191278 3237 downloads

La ciudad cerrada y su diversificación como reto del Área Metropolitana de Guadalajara, México
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Pfannenstein, Bernd

; Anacleto Herrera, Edgar Eduardo

; Sevilla Villalobos, Salvador

Revista de geografía Norte Grande

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dec 2017, N. 68 Pages 163 - 184

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The phenomenon of gated communities has evolved into a dynamic and complex object that has transformed Latin American Cities over the last decades. The Metropolitan Area of Guadalajara, Mexico, is also undergoing a retransformation of this concept. The "success” of gated residential areas in Guadalajara has been defined by the inclusion of a new economic strata into this fortified housing scheme. Fifteen percent of the built city are characterized by the modality of limited access due to physical barriers that have caused a fragmentation of this territory. Through the implementation of a geo-referenced database, a spatial analysis of the phenomenon has been accomplished in this Mexican city, showing results that confirm the conceptual modifications that several researchers have identified and that are causing a stratification of this housing model.

RESUMEN El fenómeno de las urbanizaciones cerradas se convirtió en un objeto dinámico y complejo que se ha estado transformando durante las últimas décadas, logrando un cambio similar en las ciudades latinoamericanas donde se encuentra. El Área Metropolitana de Guadalajara, México, no ha sido la excepción y padece la re-transformación del concepto. El "éxito” alcanzado por las urbanizaciones cerradas en Guadalajara llevó a la inclusión de nuevos estratos económicos en este esquema de vivienda fortificada, una inserción que se traduce en el 15% de la ciudad construida bajo la modalidad de espacio de acceso limitado gracias a la imposición de barreras físicas que fragmentan el territorio. Mediante la construcción de una base de datos georreferenciada se ha logrado un análisis preliminar del fenómeno en esta metrópolis mexicana, arrojando resultados que constatan las modificaciones conceptuales que diversos investigadores identificaron y que están causando una estratificación del modelo de vivienda.

2115 downloads

Can renal stone size and the use of the nephrolithometric system increase the efficacy of predicting the risk of failure of percutaneous nephrolithotripsy?
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FELICI, EDUARDO MEDINA

; DINIZ, ANDRÉ LUIZ LIMA

; SOUZA, TOMAS ACCIOLY

; FAVORITO, LUCIANO ALVES

; RESENDE JÚNIOR, JOSÉ ANACLETO DUTRA

Revista do Colégio Brasileiro de Cirurgiões

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dec 2017, Volume 44 N. 6 Pages 619 - 625

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: verificar a associação entre taxa de sucesso de nefrolitotripsia percutânea, escore de Guy e tamanho do cálculo. Métodos: foram avaliados 100 pacientes submetidos à nefrolitotripsia percutânea. Todos os cálculos foram classificados de acordo com o escore de Guy. Consideramos o paciente livre de cálculos quando os fragmentos residuais fossem menores ou iguais a 2mm. Resultados: de acordo com o escore de Guy, 54% tinham escore 1 (Grupo 1), 18% escore 2 (Grupo 2), 15% escore 3 (Grupo 3) e 13% escore 4 (Grupo 4) . Houve resolução de 77,77% no grupo 1, de 27,77% no grupo 2, de 26,6% no grupo 3 e de 7,69% no grupo 4. Houve significância estatística para predição de taxa livre de cálculos entre os pacientes com escore de Guy 1 quando avaliados de acordo com o tamanho do cálculo. Entre os grupos 2, 3 e 4 não houve significância estatística, porém observamos tendência de que quanto maior o tamanho do cálculo, maior a chance de cálculo residual. Conclusão: a nefrolitometria pelo Escore de Guy e o tamanho do cálculo são preditores isolados para avaliação de sucesso da nefrolitotripsia percutânea. O tamanho do cálculo pode influenciar a taxa de sucesso de pacientes com Escore de Guy 1.

ABSTRACT Objective : to verify the association of success rate of percutaneous lithotripsy, Guy score and size of the stone. Methods: one hundred patients submitted to percutaneous nephrolithotripsy were evaluated. All stones were classified according to Guy Score. Patient free of stone was considered when residual fragments were ≤2mm. Results: according to guy Score, 54% were score 1 (Group 1), 18% score 2 (Group 2), 15% score 3 (Group 3), and 13% score 4 (Group 4). Success was observed in 77.77% in Group 1, 27.77% in group 2, 26.6% in Group 3, and 7.69% in Group 4. In patients with Guy score 1, there was statistical significance of prediction of free stone rate when evaluated according to the size of the stone. Among groups 2, 3 and 4 there was no statistical significance, but it was observed a trend in relation to stone size, the bigger the higher the chance of residual fragments. Conclusion: nephrolithometry by Guy Score and size of the stone are single predictors of success of percutaneous nephrolithotripsy. Stone size may influence success rate of patients with Guy Score 1.

https://doi.org/10.1590/0100-69912017006014 11791 downloads

Antibodies for Rickettsia spp. in patients with negative serology for dengue virus, leptospirosis, and meningococcal disease in municipalities of São Paulo State, Brazil
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Prata, Juliana Anacleto Cabral

; Souza, Celso Eduardo de

; Angerami, Rodrigo Nogueira

; Barbosa, Taíse Marongio Cotrim de Moraes

; Santos, Fabiana Cristina Pereira dos

; Colombo, Silvia

; Guercio, Vânia Martins Fontes Del

; Donalísio, Maria Rita

Revista da Sociedade Brasileira de Medicina Tropical

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oct 2016, Volume 49 N. 5 Pages 567 - 571

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION Brazilian spotted fever is an infectious disease with a high mortality rate if not treated early. Differential diagnosis is difficult, as the first clinical signs are non-specific and can be confused with other diseases. The aim of the study was to investigate evidence of infection with Rickettsia rickettsii and Rickettsia parkeri in negative sera samples, collected in 2014, from patients with suspected leptospirosis, dengue fever, and meningococcal disease in Atibaia and Bragança Paulista municipalities of the State of São Paulo. METHODS The samples stored at the Institute Adolfo Lutz in Campinas were tested using an indirect immunofluorescence assay (IFA) with IgG and IgM against R. rickettsii and R. parkeri. Real-time polymerase chain reaction (PCR) testing was performed for the sera samples of patients who died (n = 3), those with initial suspicion of meningococcal disease (n = 6), and those with positive IFA results. RESULTS Of 258 samples from Bragança Paulista, 4 (1.6%) were positive, with IgG titers of 1:64 and 1:128 against R. rickettsii and R. parkeri, respectively. Of 155 samples from Atibaia, 2 (1.3%) were positive, with IgG titers of 1:64 and 1:128 against R. rickettsii and R. parkeri, respectively. No sample showed positive PCR results. CONCLUSIONS This serological investigation suggests there is evidence of exposure to Rickettsia spp. in residents of areas that have environmental conditions favorable to the spread of bacteria, in which Brazilian spotted fever incidence was not previously confirmed.

https://doi.org/10.1590/0037-8682-0023-2016 1444 downloads

Acute myocardial infarctation in patients with critical ischemia underwent lower limb revascularization
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Lins, Esdras Marques

; Barros, Jose Wellington

; Appolonio, Fernanda

; Anacleto, Eduardo

; Lima, Eduardo Cavalcanti

Jornal Vascular Brasileiro

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dec 2013, Volume 12 N. 4 Pages 284 - 288

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

CONTEXTO: A doença arterial obstrutiva periférica (DAOP) afeta os membros inferiores (MMII) e tem como principal causa a aterosclerose. Por se tratar de uma doença sistêmica, é frequente que a aterosclerose cause o envolvimento simultâneo de outros sítios arteriais, especialmente das artérias coronárias. Desta forma, os pacientes submetidos a cirurgia de reconstrução arterial periférica, devido a isquemia crítica dos MMII, apresentam maior chance de infarto agudo do miocárdico (IAM). Apesar disso, há na literatura poucos relatos que avaliem a prevalência do IAM adequadamente neste grupo de pacientes. OBJETIVO: Avaliar incidência do infarto agudo do miocárdio no pós-operatório imediato de pacientes submetidos à revascularização de MMII devido a DAOP. MATERIAL E MÉTODOS: Foram avaliados 64 pacientes portadores de DAOP submetidos a 82 cirurgias de revascularização arterial dos MMII, no período de fevereiro de 2011 a julho de 2012. Os pacientes foram submetidos no pós-operatório imediato (até 72 horas) a eletrocardiograma (ECG) e dosagem sanguínea de troponina I cardíaca. RESULTADOS: Considerando as 82 cirurgias realizadas, em cinco (6%) casos, foram encontradas alterações no ECG e elevação sanguínea da troponina I cardíaca compatíveis com infarto agudo do miocárdio. Considerando apenas as 52 cirurgias feitas por técnica convencional, a incidência de IAM foi de 9,6%. Dois pacientes evoluíram ao óbito. CONCLUSÃO: No presente estudo, a incidência do infarto agudo do miocárdio nos pacientes submetidos à revascularização arterial de membros inferiores por DAOP foi de 6%. Considerando apenas as cirurgias feitas por técnica convencional, a incidência de IAM foi de 9,6%.

BACKGROUND: Atherosclerosis is the main cause of peripheral artery occlusive disease (PAOD) of the lower limbs. Patients with PAOD often also have obstructive atherosclerosis in other arterial sites, mainly the coronary arteries. This means that patients who undergo infrainguinal bypass to treat critical ischemia have a higher risk of AMI. There are, however, few reports in the literature that have assessed this risk properly. OBJECTIVE: The aim of this study was to determine the incidence of acute myocardial infarction in patients who underwent infrainguinal bypass to treat critical ischemia of the lower limbs caused by PAOD. MATERIAL AND METHODS: A total of 64 patients who underwent 82 infrainguinal bypass operations, from February 2011 to July 2012 were studied. All patients had electrocardiograms and troponin I blood assays during the postoperative period (within 72 hours). RESULTS: There were abnormal ECG findings and elevated blood troponin I levels suggestive of AMI in five (6%) of the 82 operations performed. All five had conventional surgery. The incidence of AMI as a proportion of the 52 conventional surgery cases was 9.6%. Two patients died. CONCLUSION: There was a 6% AMI incidence among patients who underwent infrainguinal bypass due to PAOD. Considering only cases operated using conventional surgery, the incidence of AMI was 9.6%.

https://doi.org/10.1590/jvb.2013.059 4312 downloads

10.

Multiple sclerosis starting before the age of 18 years: the Brazilian experience
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Fragoso, Yara Dadalti

; Ferreira, Maria Lucia Brito

; Morales, Nivea de Macedo Oliveira

; Arruda, Walter Oleschko

; Brooks, Joseph Bruno Bidin

; Carneiro, Denise Sisterolli Diniz

; Carvalho, Margarete de Jesus

; Comini-Frota, Elizabeth Regina

; Correa, Eber Castro

; Damasceno, Carlos Augusto de Albuquerque

; Domingues, Renan Barros

; Finkelsztejn, Alessandro

; Gama, Paulo Diniz da

; Gomes, Sidney

; Goncalves, Marcus Vinicius Magno

; Grzesiuk, Anderson Kuntz

; Khouri, Jussara Mathias Netto

; Kaimen-Maciel, Damacio Ramon

; Mendes, Maria Fernanda

; Morales, Rogerio de Rizo

; Ribeiro, Sonia Beatriz Felix

; Ribeiro, Taysa Alexandrino Gonsalves Jube

; Albuquerque, Livia Brito Bezerra de

; Anacleto, Andrea

; Finkelsztejn, Juliana

; Gama, Rodrigo Assad Diniz da

; Lopes, Josiane

; Oliveira, Celso Luis Silva

; Oliveira, Francisco Tomaz Meneses

; Pires, Leopoldo Antonio

; Saldanha, Patricia Correia de Oliveira

; Souza, Adelia Henriques

; Silva, Alex Eduardo da

Arquivos de Neuro-Psiquiatria

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oct 2013, Volume 71 N. 10 Pages 783 - 787

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Esclerose múltipla (EM) com início na infância e adolescência constitui um desafio para o diagnóstico e manejo da doença. A proposta do presente estudo foi avaliar as características da EM de início precoce em pacientes brasileiros. Métodos Coleta de dados retrospectiva de arquivos de unidades especializadas em atendimento da EM. Resultados A partir de 20 unidades de EM de nove estados brasileiros, foram coletados 117 casos de EM com início antes dos 18 anos de idade. Estes pacientes tinham uma média de 10 anos de duração da doença, de maneira geral apresentavam pouca incapacidade , com um surto a cada dois anos e meio. A média de idade no início da doença era 13,7 anos. Conclusão O presente estudo apresenta uma grande série de casos brasileiros de EM pediátrica. Embora alguns pacientes tenham apresentado forma grave de EM, de maneira geral o grupo de pacientes cuja EM iniciou-se na infância ou adolescência apresentou uma forma relativamente leve da doença no Brasil.

Multiple sclerosis (MS) starting in childhood and adolescence poses a challenge for diagnosis and management of the disease. The aim of the present study was to assess the characteristics of early onset MS in Brazilian patients. Methods Retrospective data collection from specialized MS units. Results From 20 MS units in 11 Brazilian states, 117 cases of MS starting before the age of 18 years were collected. These patients had an average of 10 years of disease duration, still typically with low disability and one relapse every 2.5 years. The mean age for disease onset was 13.7 years. Conclusion The present study introduces a large series of Brazilian cases of pediatric MS. Although some patients presented a very severe form of MS, on the whole the group of patients with MS starting in childhood or adolescence presented a relatively mild form of this disease in Brazil.

https://doi.org/10.1590/0004-282X20130122 4255 downloads Cited 1 time in SciELO

11.

Perfil epidemiológico de pacientes submetidos a tratamento cirúrgico de varizes de membros inferiores
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Lins, Esdras Marques

; Barros, José Wellington

; Appolônio, Fernanda

; Lima, Eduardo Cavalcanti

; Barbosa Junior, Marcos

; Anacleto, Eduardo

Jornal Vascular Brasileiro

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dec 2012, Volume 11 N. 4 Pages 301 - 304

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

CONTEXTO: A Doença Venosa Crônica (DVC) dos membros inferiores apresenta uma alta prevalência, estando a cirurgia para cura das varizes dos membros inferiores entre as mais frequentemente realizadas pelos cirurgiões vasculares. Apesar disso, não foi estabelecido, na cidade de Recife e zona metropolitana, o perfil epidemiológico dos pacientes que são submetidos a essa modalidade terapêutica. OBJETIVOS: O objetivo deste trabalho foi avaliar o perfil epidemiológico dos pacientes suubmetidos à cirurgia para a cura das varizes dos membros inferiores. MATERIAL E MÉTODOS: Foram avaliados 201 pacientes submetidos ao tratamento cirúrgico de varizes dos membros inferiores, no Serviço de Cirurgia Vascular no Instituto de Medicina Integral Professor Fernando Figueira (IMIP), no período de agosto de 2006 a abril de 2007. Foram avaliados os seguintes parâmetros: sexo, idade, sedentarismo, sobrepeso e obesidade, e presença de ortostatismo prolongado durante atividade laboral. RESULTADOS: Do total de pacientes avaliados, 175 (87,1%) eram do sexo feminino e 26 (12,9%) do masculino. A faixa etária mais acometida foi a de 41 a 50 anos (32,3%), o sobrepeso estava presente em 38,8% dos pacientes, e a obesidade em 7,5% dos casos. O ortostatismo prolongado, durante a atividade laboral, estava presente em 82,1% dos pacientes avaliados. O grau de escolaridade mais comum, observado em 83,2% dos pacientes, foi de até oito anos de tempo de estudo. O sedentarismo foi encontrado em 69,2% dos pacientes. CONCLUSÃO: A maioria dos pacientes avaliados no presente estudo era do sexo feminino com idade maior que 40 anos, era sedentária e não apresentava sobrepeso ou obesidade, e desenvolvia atividades laborais com ortostatismo prolongado.

BACKGROUND: The Chronic Venous Insufficiency of lower limbs has a high prevalence, and its surgical treatment is one of the most performed. Even so, it has not been reported the epidemiologic profile of the patients that has been underwent to this surgery in the city of Recife. OBJECTIVE: The aim of this report was evaluate the epidemiologic profile of the patients underwent to varicose vein surgery of the lower limbs. MATERIAL AND METHODS: They were evaluated 201 patients underwent to varicose vein surgery of the lower limbs at the Vascular Surgery Service at the Instituto de Medicina Integral Professor Fernando Figueira (IMIP) from august 2006 to april 2007. All the patients were evaluated considering the gender, age, sedentarism, overweight, obesity and the report of long-time in a standing position during work shift. RESULTS: Over all patients evaluated, 175 (87.1%) were females and 26 (12.9%) males. The majority of them (32.3%) were aged from 41 to 50 years, overweight was found in 38.8% of the patients, and obesity in 7.5% of the cases. Long time standing during work shift was reported by 82.1% of the patients, and the time at the school, found in 83.2% of the patients, was eight or less years. Sedentarism was found in 69.2% of the patients. CONCLUSION: The majority of the patients evaluated in the present study was female and more than 40 years-old, reported sedentarism, did not have overweight or obesity and reported to stay a long-time in a standing position during work shift.

7838 downloads Cited 4 times in SciELO

12.

Detección de Helicobacter pylori en placa dental y en mucosa gástrica de pacientes sometidos a endoscopia digestiva
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Scarano Pereira, Giuseppe Anacleto

; Correia de Medeiros, Arnaldo

; Marques Soares, Maria Sueli

; Chimenos Küstner, Eduardo

; de Castro Barreto, Rosimar

; Perdomo Lovera, Mónica

Acta Odontológica Venezolana

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may 2005, Volume 43 N. 2 Pages 113 - 118

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

El objetivo de este estudio fue determinar la presencia de Helicobacter pylori en placa dental y en mucosa gástrica de pacientes adultos. Se seleccionaron 48 pacientes, que habían de someterse a endoscopia por indicación médica. En todos los pacientes se recogió placa dental antes de la endoscopia. A partir de la placa dental se realizó extracción de ADN, con finalidad de identificar H. pylori por el método de Reacción en Cadena de la Polimerasa (RCP o PCR). Posteriormente, los pacientes fueron sometidos a endoscopia digestiva, mediante la cual se tomaron muestras de mucosa gástrica. A continuación se extrajo ADN para la posterior identificación de H . pylori por el método PCR. La presencia de H. pylori fue observada en el 100% de las muestras de placa dental y en el 66,67% de las de mucosa gástrica. De los 48 pacientes se constató que 42 (87,5%) presentaban alteraciones gastroduodenales y, entre ellos, 29 (69,05%) presentaron reacción positiva para Helicobacter pylori en placa dental y en mucosa gástrica. Entre los 6 pacientes con endoscopia normal se encontraron 3 casos (50%) con presencia simultánea de H. pylori en placa dental y mucosa gástrica. Los resultados de este estudio sugieren la presencia simultánea de H. pylori en placa dental y mucosa gástrica en elevadas proporciones. Estos resultados permiten sugerir además que la placa dental puede constituir un reservorio importante de este microorganismo.

The objective of this study was to determine the prevalence of Helicobacter pylori in dental plaque and in gastric mucosa. 48 subjects that were submeted to endoscopy for medical indication were selected. In all the patients plaque samples were collected before the endoscopy. DNA was extracted from the samples and evaluated for the presence de H. pylori using Polymerase Chain Reaction(PCR) method. After collection of oral samples one biopsy was collected in biopsy gastric of each subject. DNA was extracted and H. pylori identified using PCR method. The presence of Helicobacter pylori was observed in 100% of the samples oral and in 66,67% of gastric mucosa. We verified that 42 pactients (87.5%) presented gastroduodenales alterations and 29 of them (69,05%) presented positive reaction for H. pylori in dental plaque and gastric mucosa. In the 6 subjects with normal endoscopy were registered 3 cases (50%) with simultaneous presence of H. pylori in dental plaque and in gastric mucosa. The results of this study suggest the simultaneous presence of H. pylori in dental plaque and gastric mucosa in high percentage and that the dental plaque can represent reservoirs for this pathogen.

objetivo deste estudo era determinar a presença de Helicobacter Pylori na placa dental e na mucosa gástrica do pacientes adulto. 48 pacientes selecionaram-se, aquele lá era ser posto sob a endoscopia pela indicação médica. Todos os em pacientes a placa dental fez exame do abrigo antes da endoscopia. Do DNA dental da placa a extração foi feita, com finalidade de identificar H. pylori pelo método da reação cadeia do polymerasa (RCP ou PCR). Mais tarde, os pacientes foram postos sob a endoscopia digestiva, por meio de que amostras foram feitas exame da mucosa gástrica. O DNA seguinte para a identificação mais atrasada de H foi extraído. Pylori por método PCR. A presença de H. pylori foram observados nos 100% das às mostras da placa dental e dentro 66.67% da que lês da mucosa gástrica. Dos 48 pacientes indicou-se que 42 (87.5%) presentaron alterações dos gastroduodenales e, entre eles, presentan reaccion positivo de 29 (69.05%) para Helicobacter pylori na placa dental e na mucosa gástrica. Entre os seis pacientes com endoscopia normal estavam três casos (50%) com presença simultânea de H. pylori na placa dental e mucousa gástrica. Os resultados deste estudo sugerem a presença simultânea de H. pylori na placa dental e mucousa gástrica em proporções elevadas. Estes resultados reservam para sugerir além que a lata dental da placa constitua o reservorio importante.

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