Abstract The mesoeucrocodylian record from the Bauru Group (Paraná Basin, Brazil) comes from three formations: Adamantina (Late Turonian–Early Maastrichtian), Presidente Prudente (Early Campanian–Early Maastrichtian) and Marília (Maastrichtian). These records are restricted to the Early Coniacian–Early Maastrichtian. Here, we report a new crocodyliform record from the Bauru Group, which was the first of the Araçatuba Formation, from a new locality of Coronel Goulart district, in Álvares Machado municipality. Coronelsuchus civali gen. nov. et sp. nov. comprises two related specimens - FFP PG 13 and FFP PG 14 recovered close to each other and on the same muddy sandstone level. We perform a phylogenetic analysis with 392 characters (five new added) and 88 taxa. Our analyses supported the new clades: Sphagesauria, Sphagesaurinae and Caipirasuchinae. Our phylogenetic results suggest C. civali as a basal Sphagesauria. Regarding the Crocodyliform Assemblage Zones (CAZ), the new species is correlated to the CAZ 1, together with small sphagesaurians, Caryonosuchus and itasuchids. The C. civali reveals an older appearing (pre-Turonian) and diversification of Sphagesauria. The specimens also expand the stratigraphic range for Notosuchia in the Bauru Group.

RESUMO A produção de biomassa de trigo voltada para a elaboração de silagem de qualidade é dependente da precipitação, da temperatura e do nitrogênio. O objetivo no estudo foi validar o uso da precipitação, soma térmica e nitrogênio como variáveis potenciais para composição do modelo de regressão linear múltipla e a simulação da produtividade de biomassa do trigo na elaboração de silagem nas condições de fornecimento de nitrogênio durante o ciclo, nos sistemas de sucessão. O estudo foi conduzido em 2012, 2013 e 2014 em blocos ao acaso com quatro repetições em fatorial 4 x 3, para doses de N-fertilizante (0, 30, 60, 120 kg ha-1) e formas de fornecimento [único (100%) no estádio V3 (terceira folha expandida); fracionado (70%/30%) no estádio V3/V6 (terceira e sexta folha expandida) e fracionado (70%/30%) no estádio V3/E (terceira folha expandida e início do enchimento de grãos)] respectivamente, no sistema soja/trigo e milho/trigo. A precipitação e o nitrogênio são variáveis potenciais na composição do modelo de regressão linear múltipla. Os modelos de regressão linear múltipla são eficientes para simulação da produtividade de biomassa do trigo para silagem nas condições de fornecimento de nitrogênio durante o ciclo nos sistemas de sucessão.

ABSTRACT Wheat biomass yield focused on the production of quality silage is dependent on rainfall, temperature and nitrogen (N). The objective of the study was to validate the use of rainfall, thermal time and N as potential variables for the composition of the multiple linear regression model and simulation of wheat biomass yield for silage production under N supply conditions during the cycle, in the systems of succession. The study was conducted in 2012, 2013 and 2014, in randomized blocks with four replicates in 4 x 3 factorial, for N-fertilizer doses (0, 30, 60, 120 kg ha-1) and forms of N supply [single application (100%) in the stage V3 (third expanded leaf); split application (70%/30%) in the stages V3/V6 (third and sixth expanded leaves); split application (70%/30%) in the stages V3/E (third expanded leaf and beginning of grain filling)], respectively, in the systems soybean/wheat and maize/wheat. Rainfall and N are potential variables in the composition of the multiple linear regression model. Multiple linear regression models are efficient in the simulation of wheat biomass yield for silage under the N supply conditions during the cycle in the succession systems.

FUNDAMENTO: A hipertensão arterial pulmonar é uma doença grave e progressiva. O maior desafio clínico é seu diagnóstico precoce. OBJETIVO: Avaliar a presença e a extensão do realce tardio miocárdico pela ressonância magnética cardíaca bem como verificar se o percentual da massa de fibrose miocárdica é indicador de gravidade. MÉTODOS: Estudo transversal com 30 pacientes com hipertensão arterial pulmonar dos grupos I e IV, submetidos às avaliações clínica, funcional e hemodinâmica, e à ressonância magnética cardíaca. RESULTADOS: A média de idade dos pacientes foi de 52 anos, com predomínio do gênero feminino (77%). Dentre os pacientes, 53% apresentavam insuficiência ventricular direita ao diagnóstico, e 90% encontravam-se em classe funcional II/III. A média do teste de caminhada de 6 minutos foi de 395 m. No estudo hemodinâmico com o cateterismo direito, a média da pressão arterial pulmonar foi de 53,3 mmHg, do índice cardíaco de 2,1 L/min.m², e a mediana da pressão atrial direita foi de 13,5 mmHg. Realce tardio do miocárdio pela ressonância magnética cardíaca foi encontrado em 28 pacientes. A mediana da massa de fibrose foi 9,9 g e do percentual da massa de fibrose de 6,17%. A presença de classe funcional IV, insuficiência ventricular direita ao diagnóstico, teste de caminhada de 6 minutos < 300 metros e pressão atrial direita > 15 mmHg, com índice cardíaco < 2,0 L/min.m², teve associação significativa com maior percentual de fibrose miocárdica. CONCLUSÃO: O percentual da massa de fibrose miocárdica mostra-se um marcador não invasivo com perspectivas promissoras na identificação do paciente portador de hipertensão pulmonar com fatores de alto risco.

BACKGROUND: Pulmonary arterial hypertension is a severe and progressive disease. Its early diagnosis is the greatest clinical challenge. OBJECTIVE: To evaluate the presence and extension of the delayed myocardial contrast-enhanced cardiovascular magnetic resonance, as well as to verify if the percentage of the myocardial fibrosis mass is a severity predictor. METHODS: Cross-sectional study with 30 patients with pulmonary arterial hypertension of groups I and IV, subjected to clinical, functional and hemodynamic evaluation, and to cardiac magnetic resonance. RESULTS: The mean age of patients was 52 years old, with female predominance (77%). Among the patients, 53% had right ventricular failure at diagnosis, and 90% were in functional class II/III. The mean of the 6-minute walk test was 395m. In hemodynamic study with right catheterism, the mean average pulmonary arterial pressure was 53.3mmHg, of the cardiac index of 2.1L/ min.m², and median right atrial pressure was 13.5 mmHg. Delayed myocardial contrast-enhanced cardiovascular magnetic resonance was found in 28 patients. The mean fibrosis mass was 9.9 g and the median percentage of fibrosis mass was 6.17%. The presence of functional class IV, right ventricular failure at diagnosis, 6-minute walk test < 300 meters and right atrial pressure > 15mmHg, with cardiac index < 2.0L/ min.m², there was a relevant association with the increased percentage of myocardial fibrosis. CONCLUSION: The percentage of the myocardial fibrosis mass indicates a non-invasive marker with promising perspectives in identifying patients with high risk factors for pulmonary hypertension.

A method using LC/ESI-MS/MS for the quantitative analysis of Ochratoxin A in roasted coffee was described. Linearity was demonstrated (r = 0.9175). The limits of detection and quantification were 1.0 and 3.0 ng g-1, respectively. Trueness, repeatability and intermediate precision values were 89.0-108.8%; 2.4-13.7%; 12.5-17.8%, respectively. To the best of our knowledge, this is the first report in which Ochratoxin A in roasted coffee is analysed by LC/ESI-MS/MS, contributing to the field of mycotoxin analysis, and it will be used for future production of Certified Reference Material.

OBJETIVO: Determinar a prevalência e a associação de obesidade central (CO) e hipertensão e suas associações com consumo de álcool, fumo e atividade física em adolescentes. SUJEITOS E MÉTODOS: Estudo de corte transversal em 1.824 estudantes de 29 escolas públicas em Recife. RESULTADOS: 89,6% com peso normal, 6,7% sobrepeso e 3,7% obesidade; 77,2% normotensos, 5,9% pré-hipertensos e 16,9% hipertensos; 10,2% de CO quando utilizado percentil 90 como ponto de corte e de 25,2% quando utilizado percentil 75. Houve maior probabilidade de CO entre os estudantes com 18 a 20 anos, fumantes e consumo de álcool. A probabilidade de hipertensão aumenta nos homens, com WC (waist circumference) > 90, WC > 75 e sem atividade física. CONCLUSÕES: Elevada prevalência de CO e hipertensão foi encontrada em adolescentes. CO foi mais frequente nos estudantes com 18 a 20 anos, fumantes, e consumo de álcool e hipertensão foram associados com sexo masculino, CO e ausência de atividade física.

OBJECTIVE: To determine the prevalence and association of central obesity (CO) and hypertension and its associations with alcohol intake, smoking and physical activity in adolescents. SUBJECTS AND METHODS: Cross sectional study in 1,824 students from 29 public schools in Recife. RESULTS: 89.6% were normal weight, 6.7% overweight and 3.7% obese; 77.2% were normotensive, 5.9% prehypertensive and 16.9% hypertensive; CO was 10.2% when the 90th percentile was used as cutoff and 25.2% when the 75th percentile was used. There was a higher likelihood of central obesity among students aged 18 to 20 years, smoking and alcohol intake. The probability of hypertension increases if the subject is male, has a waist circumference (WC) > 90, WC > 75 and does not practice physical activity. CONCLUSIONS: A high prevalence of CO and hypertension was found in adolescents. CO was more frequent in students aged 18 to 20 years, smokers and with alcohol intake and hypertension was associated with male, CO and no physical activity.