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ABSTRACT Background Several therapies have been used or proposed for the treatment of COVID-19, although their effectiveness and safety have not been properly evaluated. The purpose of this document is to provide recommendations to support decisions about the drug treatment of outpatients with COVID-19 in Brazil. Methods A panel consisting of experts from different clinical fields, representatives of the Brazilian Ministry of Health, and methodologists (37 members in total) was responsible for preparing these guidelines. A rapid guideline development method was used, based on the adoption and/or adaptation of recommendations from existing international guidelines combined with additional structured searches for primary studies and new recommendations whenever necessary (GRADE-ADOLOPMENT). The rating of quality of evidence and the drafting of recommendations followed the GRADE method. Results Ten technologies were evaluated, and 10 recommendations were prepared. Recommendations were made against the use of anticoagulants, azithromycin, budesonide, colchicine, corticosteroids, hydroxychloroquine/chloroquine alone or combined with azithromycin, ivermectin, nitazoxanide, and convalescent plasma. It was not possible to make a recommendation regarding the use of monoclonal antibodies in outpatients, as their benefit is uncertain and their cost is high, with limitations of availability and implementation. Conclusion To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.

https://doi.org/10.1016/j.bjid.2022.102347

Celso Furtado, intérprete do Brasil
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Barbosa, Alexandre de Freitas

Revista do Instituto de Estudos Brasileiros

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jan 2021, N. 78 Pages 86 - 107

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O presente artigo procura discutir a originalidade da interpretação do Brasil contida em Formação econômica do Brasil , obra clássica de Celso Furtado. Para tanto, são recuperadas as matrizes formadoras do seu pensamento no sentido de mostrar como são operacionalizadas por meio do seu método histórico-estrutural. O plano da obra, o método e o estilo permitem entrosar passado, presente e futuro de modo inovador, trazendo novas possibilidades de compreensão e transformação do Brasil. Finalmente, o artigo estabelece um diálogo com as interpretações predecessoras de Gilberto Freyre, Sérgio Buarque de Holanda e Caio Prado Jr.

ABSTRACT This article seeks to discuss the originality of the interpretation of Brazil undertaken in the book “Formação econômica do Brasil”, Furtado’s masterpiece. In order to do so, it highlights the main tenets of his thought, which paved the way for Furtado’s historical-structuralist method. The structure of the book, its method and style allowed the interplay of different spaces and times in such an innovative way that opened new potential avenues for understanding and changing the Brazilian reality of his time. At last, it establishes a dialogue between this interpretation of Brazil and the ones launched by his predecessors: Gilberto Freyre, Sérgio Buarque de Holanda and Caio Prado Jr.

https://doi.org/10.11606/issn.2316-901x.v1i78p86-107 147 downloads

Celso Furtado, transdisciplinar e contemporâneo
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Barbosa, Alexandre de Freitas

; Botelho, André

; Cepêda, Vera Alves

; Saes, Alexandre Macchione

Revista do Instituto de Estudos Brasileiros

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jan 2021, N. 78 Pages 17 - 24

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.11606/issn.2316-901x.v1i78p17-24 79 downloads

Safe intra-hospital care in context of vulnerability to socio-environmental disasters: implications for nursing
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Rocha, Mayra Wilbert

; Oliveira, Alexandre Barbosa de

; Araújo, Diego Freitas de

; Queiroz, Ana Beatriz Azevedo

; Paes, Graciele Oroski

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 1 elocation e20190223

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to analyze the factors involved in safe intra-hospital care, in a context of vulnerability to socio-environmental disasters and their implications for nursing. Methods: a cross-sectional study of a descriptive and exploratory nature. Semi-structured interviews were conducted with 49 nursing professionals from a hospital in the mountainous region of the state of Rio de Janeiro (Brazil), which suffered a significant impact from a socio-environmental disaster in January 2011. Data were processed by software IRaMuTeQ. Results: aspects related to disaster assistance were presented through a thematic chunk with four classes, through descending hierarchical classification. Conclusions: for better nursing response in socio-environmental disasters, in an intra-hospital setting, investments for training and continuing education should be prioritized; adequate provision and provision of human, material and technological resources; psychological support for professionals after such events; appropriation of nursing competencies for the development of advanced practices in disasters and effective risk management.

RESUMEN Objetivos: analizar los factores que intervienen en la atención hospitalaria segura, en un contexto de vulnerabilidad a los desastres socioambientales y sus implicaciones para la enfermería. Métodos: estudio transversal, descriptivo y exploratorio. Se llevaron a cabo entrevistas semiestructuradas con 49 profesionales de enfermería de un hospital en la región montañosa del estado de Río de Janeiro (Brasil), que sufrió un impacto significativo de un desastre socioambiental en enero de 2011. Los datos se trataron utilizando el software IRaMuTeQ. Resultados: los aspectos relacionados con la asistencia en desastres se presentaron a través de un bloque temático con cuatro clases, a través de una clasificación jerárquica descendente. Conclusiones: para una mejor respuesta de enfermería en desastres socioambientales, en un entorno intrahospitalario, se deben priorizar las inversiones en capacitación y educación permanente; la previsión y disponibilidad adecuada de recursos humanos, materiales y tecnológicos; el apoyo psicológico para profesionales después de tales eventos; y la apropiación de habilidades de enfermería para el desarrollo de prácticas avanzadas en desastres y la gestión eficaz de riesgos.

RESUMO Objetivos: analisar os fatores intervenientes na assistência intra-hospitalar segura, em contexto de vulnerabilidade a desastres socioambientais e suas implicações para a enfermagem. Métodos: estudo transversal, de natureza descritiva e exploratória. Foram desenvolvidas entrevistas semiestruturadas com 49 profissionais de enfermagem de um hospital da região serrana do estado do Rio de Janeiro (Brasil), que sofreu significativo impacto de desastre socioambiental em janeiro de 2011. Os dados foram tratados pelo software IRaMuTeQ. Resultados: os aspectos relacionados à assistência em desastres foram apresentados por meio de bloco temático com quatro classes, através de classificação hierárquica descendente. Conclusões: para melhor resposta da enfermagem em desastres socioambientais, em cenário intra-hospitalar, devem ser priorizados investimentos para capacitação e educação permanente; previsão e disponibilização adequada de recursos humanos, materiais e tecnológicos; suporte psicológico para profissionais após tais eventos; e apropriação de competências de enfermagem para o desenvolvimento de práticas avançadas em desastres e efetivo gerenciamento de riscos.

https://doi.org/10.1590/0034-7167-2019-0223 10 downloads

Safe intra-hospital care in context of vulnerability to socio-environmental disasters: implications for nursing
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Rocha, Mayra Wilbert

; Oliveira, Alexandre Barbosa de

; Araújo, Diego Freitas de

; Queiroz, Ana Beatriz Azevedo

; Paes, Graciele Oroski

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 1 elocation e20190223

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2019-0223 826 downloads

“Developmentalist Brazil” (1945-1964) as a concept: historicizing and (re)periodizing development in Brazil
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BARBOSA, ALEXANDRE DE FREITAS

Brazilian Journal of Political Economy

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jun 2020, Volume 40 N. 2 Pages 332 - 354

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O artigo apresenta uma periodização alternativa do debate e prática de desenvolvimento no Brasil. Na primeira parte, é realizada uma recuperação da trajetória de Rômulo Almeida. O texto aponta como, durante o segundo governo Vargas, um grupo de burocratas - cunhados como “intelectuais orgânicos do Estado” - passa a ocupar uma nova posição social. À medida que o processo de industrialização avança, surgem novas contradições, junto com outras posições sociais. Na segunda parte, novas categorias são construídas para identificar as diferentes concepções de desenvolvimento durante o período 1945-1964. Em seguida, depois de realizar uma reconstituição dos vários usos do “desenvolvimentismo” ao longo da história do Brasil, o texto aprofunda o conceito de “Brasil Desenvolvimentista”, com o intuito de capturar a dinâmica interna do período. O objetivo é integrar ideias e posições sociais, de um lado, e processos estruturais, de outro, de modo a confrontar as estratégias de desenvolvimento. O período “pós-desenvolvimentista” (1964-1980) é caracterizado como uma ruptura na sua tentativa de lançar um novo padrão de desenvolvimento para superar as crescentes contradições vividas durante o “Brasil Desenvolvimentista” (1945-1964). Ao final, é esboçado um programa de pesquisa que poderia auxiliar na compreensão das transformações estruturais ocorridas no Brasil no contexto da nova economia-mundo capitalista pós-1980.

ABSTRACT The paper presents an alternative periodization of the debate and practice of development in Brazil. It starts with a brief depiction of Rômulo Almeida’s trajectory. It states that during the second Vargas government, a group of bureaucrats - coined as “State organic intellectuals” - occupy a new social position. As the process of economic development unfolds, new contradictions arise, so as other social positions. In the second part, new categories are constructed in order to describe the different conceptions of development during the period 1945-1964. Then, after presenting the many uses of the concept of “developmentalism” over history, the paper delves into the concept of “Developmentalist Brazil” in order to get into the inner dynamic of the period. The purpose is to integrate ideas and social positions, on the one hand, and structural processes, on the other, by addressing the conflicts over development strategies. The “Post-Developmentalist” period (1964-1980) is characterized as a rupture in its attempt to put in place a new development pattern to solve the rising contradictions faced during the “Developmentalist Brazil” period (1945-1964). At the end, we put forth a research programme that could possibly lead to the understanding of Brazil’s structural changes in the context of the post-1980 new capitalist world-economy.

https://doi.org/10.1590/0101-31572020-3091 1234 downloads

Música, arte e sociabilidade no Brasil
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Barbosa, Alexandre de Freitas

; Paixão, Fernando

; Dantas, Monica Duarte

Revista do Instituto de Estudos Brasileiros

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aug 2019, N. 73 Pages 13 - 15

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.11606/issn.2316-901x.v0i73p13-15 419 downloads

Uma economia política da poesia drummondiana
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Barbosa, Alexandre de Freitas

Revista do Instituto de Estudos Brasileiros

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aug 2019, N. 73 Pages 275 - 279

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O texto procura ressaltar a contribuição de José Miguel Wisnik em seu livro recente. Nessa obra, o autor realiza uma fusão entre a história do desenvolvimento e da mineração no Brasil, que teve como marco a criação da Companhia Vale do Rio Doce (CVRD), e a invenção poética drummondiana, profundamente afetada pelo dest ino de Itabira, sua cidade natal. Tempo e espaço são aniqui lados durante o processo de desenvolvimento econômico, mas também ressignificados criativamente pelo poeta, que vê o território onde se deu o seu processo de sociabilidade ser literalmente soterrado pela atuação da empresa. A Vale S.A., tal como renomeada em 2007, apenas depois das catástrofes de Mariana e Sobradinho parece ecoar o grito de dor do poeta, cuja inteligibilidade não era acessível aos seus contemporâneos .

ABSTRACT The paper seeks toshed light on José Miguel Wisnik’s contribution in his recent book. He integrates the history of development and mining in Brazil, which had as one of its hallmarks the creation of Rio Doce Valley Corporation (CVRD in Portuguese), and Drummond’s poetic invention, deeply affected by the fate of Itabira, his hometown. Time and space are totally shattered by the process of economic development, but also creatively resignified by the poet who sees the territory of his early sociability buried by the enterprise activity. Vale S.A., as it was renamed in 2007, only af ter the tragedies of Mariana and Brumadinho seems to convey the poet’s echo of pain, not intelligible by his contemporaries.

https://doi.org/10.11606/issn.2316-901x.v0i73p275-279 401 downloads

Região, regionalismo e outros espaços: deslocamentos
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Barbosa, Alexandre de Freitas

; Paixão, Fernando

; Dantas, Monica Duarte

Revista do Instituto de Estudos Brasileiros

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apr 2019, N. 72 Pages 13 - 17

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.11606/issn.2316-901x.v0i72p13-17 212 downloads

10.

Echocardiographic Study of the Coronary Sinus in the Indeterminate Form of Chagas Disease
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Machado, Glauco Andre

; Anjos, Dalton Alexandre dos

; Rodrigues, Flávia de Freitas

; Anjos, Renata Fockink dos

; Luckemeyer, Marcelo Barbosa Melo

; Vasconcelos, Daniel França

; Castro, Cleudson Nery de

Revista da Sociedade Brasileira de Medicina Tropical

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dec 2018, Volume 51 N. 6 Pages 827 - 830

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION: We investigated the occurrence of coronary sinus abnormalities in the indeterminate form of Chagas disease (CD). METHODS: Differences between the maximum and minimum diameters of the coronary sinus (∆%) on echocardiography were evaluated in individuals with the indeterminate form of CD (n=14) and those without (n=16) CD. The association of the difference with abnormalities detected by echocardiography and myocardial scintigraphy was assessed. RESULTS: The mean Δ% values did not differ significantly between the groups. There was no correlation of the measurements with echocardiographic and myocardial scintigraphy findings. CONCLUSIONS: The coronary sinus evaluation revealed no differences between the groups.

https://doi.org/10.1590/0037-8682-0462-2017 737 downloads

11.

Incidence and Characteristics Angiographic of Patients with Acute Myocardial
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Bachur, Cynthia Kallás

; Bachur, José Alexandre

; Machado, Juliana Pereira

; Veiga, Eugenia Velludo

; Candido, Sarah da Silva

; Barbosa, Ricardo

; Carraro, Julia Granado

; Gonçalves, Danielle de Freitas

; Tonello, Maria Georgina Marques

International Journal of Cardiovascular Sciences

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oct 2018, Volume 31 N. 5 Pages 527 - 531

Abstract: En | Text: En | PDF: En

Abstract Background: Acute myocardial infarction (AMI) is defined as the death of cardiomyocytes due to prolonged ischemia, caused by thrombosis and / or vasospasm on an atherosclerotic plaque. Objective: To determine the incidence of patients with myocardial infarction undergoing primary angioplasty; characterize the anthropometric variables and identify the risk factors in this population. Methods: This was a cross-sectional, observational, retrospective study in which we collected secondary data from medical records of a hospital in a city in the state of São Paulo, where the largest number of interventions is via Public Health System, patients with a diagnosis of Myocardial Infarction, undergoing primary coronary angioplasty, from January 2011 to December 2013. Results: The total sample consisted of 437 subjects, 282 male and 155 female. In this study, there was predominance of myocardial infarction in the anterior descending artery ADA (45.51%), followed by right coronary artery RCA (38.46%), in carrying out the rescue angioplasty and stent implantation in 96.62% of cases. There was a predominance of high blood pressure as risk factors for 73.71%, followed by smoking with 41.66% of the sample. Conclusion: According to the present study data, it appears a higher prevalence of infarction occurred in the ADA, with individuals performing the rescue angioplasty procedure and the placement of the stent, and a growing incidence of drug stent placement. We observed a high incidence of risk factors, prevailing hypertension. (Int J Cardiovasc Sci. 2018; [online].ahead print, PP.0-0).

https://doi.org/10.5935/2359-4802.20180061 380 downloads

12.

As mulheres e seus arquivos
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Barbosa, Alexandre de Freitas

; Paixão, Fernando

; Dantas, Monica Duarte

Revista do Instituto de Estudos Brasileiros

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sep 2018, N. 71 Pages 14 - 17

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.11606/issn.2316-901x.v0i71p14-17 452 downloads

13.

Fadiga dos músculos extensores do punho diminui a força de preensão palmar
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Souza, Vitor Kinoshita

; Claudino, Adrian Freitas

; Kuriki, Heloyse Uliam

; Marcolino, Alexandre Marcio

; Fonseca, Marisa de Cássia Registro

; Barbosa, Rafael Inácio

Fisioterapia e Pesquisa

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mar 2017, Volume 24 N. 1 Pages 100 - 106

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO O objetivo deste estudo foi avaliar os efeitos de um protocolo de fadiga dos músculos extensores de punho na força de preensão e da pinça lateral através da dinamometria e eletromiografia de superfície (EMG). Foram selecionados 40 indivíduos do sexo masculino, divididos em dois grupos: preensão ou pinça lateral. O protocolo de fadiga foi baseado no teste de 1 Repetição Máxima (1-RM), seguido da realização do movimento de extensão de punho repetidas vezes com carga de 75% da 1-RM. Os voluntários realizaram as tarefas de preensão ou pinça lateral associadas à dinamometria. A EMG foi realizada para ambos os grupos, analisando o comportamento, segundo o protocolo, pela frequência mediana (FM) do extensor radial do carpo (ERC), do extensor ulnar do carpo (EUC) e do flexor superficial dos dedos (FD). A dinamometria de preensão ou pinça lateral e a EMG foram realizadas antes e após o protocolo de fadiga para ambos os grupos. O protocolo de fadiga foi eficaz na diminuição da força de preensão palmar (43,5±3,85 kgf inicial e 36,50±5,1 kgf final) e da pinça lateral (10,26±1,01 kgf inicial e 8,54±0,86 kgf final), bem como na diminuição da FM, sugerindo uma condição de fadiga do EUC no grupo preensão. Os achados do presente estudo possibilitam relacionar a fadiga dos extensores de punho à diminuição de força em atividades funcionais, como a preensão, o que pode implicar em disfunções musculoesqueléticas do membro superior.

ABSTRACT The objective of this study was to evaluate the effects of a wrist extensor muscles fatigue protocol at the handgrip and lateral pinch strength through dynamometry and surface electromyography (EMG). Forty male individuals were divided into two groups: handgrip and lateral pinch group. The fatigue protocol was based on the 1 Maximal Repetition (1-MR) test, followed by wrist extension movement repeated multiple times with a load of 75% of 1-MR. The volunteers performed hand grip and lateral pinch with a dynamometer. Surface EMG was performed by both groups to analyze the behavior of median frequency (MF) during a fatigue protocol. The muscles extensor carpi radialis longus and brevis, extensor carpi ulnaris, extensor digitorum and flexor digitorum superficialis were analyzed. The strength and EMG evaluations were carried out before and after the fatigue protocol in both groups. The fatigue protocol was effective on hand grip strength reduction (43.5±3.85 kgf in baseline and 36.50±5.1 kgf final) and lateral pinch strength reduction (10.26±1.01 kgf in baseline and 8.54±0.86 kgf final) (p<0.05, 95% CI). At the EMG analysis, using median frequency, an ulnaris carpal extensor muscle fatigue at the handgrip group was evidenced. The findings indicate that wrist extensors fatigue can decrease the strength in functional activities such as handgrip, resulting in upper limb dysfunctions.

RESUMEN En este estudio se evalúa los resultados de un protocolo de fatiga de los músculos extensores de muñeca en la fuerza de presión y de pinza empleando la dinamometría y la electromiografía de superficie (EMG). Se eligieron a cuarenta hombres, los cuales fueron divididos en dos grupos: el de presión y el de pinza lateral. Se basó el protocolo de fatiga en la prueba de 1 Repetición Máxima (1RM), y se realizó el movimiento de extensión de muñeca muchas veces con carga del 75% de la 1RM. Los participantes realizaron la tarea de prensión o de pinza lateral asociada a la de dinamometría. La EMG fue realizada por ambos grupos, en los que se evaluó el comportamiento ante el protocolo de la frecuencia mediana (Fm) del extensor radial del carpo (ERC), del extensor cubital del carpo (ECC) y del flexor superficial de los dedos (FD). Se realizaron la dinamometría de presión o de pinza lateral y la EMG antes y después del protocolo de fatiga en ambos grupos. El protocolo de fatiga fue eficaz en la disminución de la fuerza de presión palmar (43,5±3,85 kgf inicial y 36,50±5,1 kgffinal) y de pinza lateral (10,26±1,01 kgf inicial y 8,54±0,86 kgf final), así como en la disminución de la Fm, lo que demuestra una condición de fatiga del ECC en el grupo de presión. Los resultados de este estudio permiten relacionar la fatiga de los extensores de muñeca a la disminución de fuerza en las actividades funcionales, lo que puede causar trastornos musculoesqueléticos del miembro superior.

https://doi.org/10.1590/1809-2950/17328524012017 7609 downloads

14.

O Mercado De Trabalho: Uma Perspectiva De Longa Duração
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BARBOSA, ALEXANDRE DE FREITAS

Estudos Avançados

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aug 2016, Volume 30 N. 87 Pages 7 - 28

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

resumo O presente artigo tem por objetivo traçar as características gerais do processo de formação do mercado de trabalho no Brasil. Três períodos são priorizados: colônia; a transição de 1850 a 1930; e a nacionalização do mercado de trabalho (1930 a 1980). Os elementos estruturais de cada período são esmiuçados. Dessa forma, procura-se apontar para os elementos de continuidade e descontinuidade que darão sentido ao mercado de trabalho no Brasil durante a consolidação do capitalismo. O resultado é um mercado de trabalho heterogêneo, com altas taxas de assalariamento, mas também caracterizado pela precarização sob várias formas, gerando uma sociedade desigual, mas num sentido completamente diferente do verificado nos períodos anteriores. Ainda assim, o peso da história é uma presença ativa nessa sociedade capitalista, moderna e excludente.

abstract This article outlines the general characteristics underpinning the development of the labor market in Brazil. Three periods are focused: colonial, transition from 1850 to 1930, and nationalization of the labor market (1930 to 1980). The structural components of each period are scrutinized and we focus on the interaction between continuity and discontinuity in the labor market during the consolidation of capitalism in Brazil. The result has been a heterogeneous labor market, with a high proportion of wage earners, but also characterized by various forms of precariousness and informality that paved the way for an unequal society, albeit in a completely different sense than that observed in other periods of Brazilian history. Nevertheless, the weight of history should not be neglected in this capitalist, modern and exclusionary society.

https://doi.org/10.1590/S0103-40142016.30870002 14126 downloads

15.

"Era Lula", "Desenvolvimentismo" e as desigualdades estruturais
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Barbosa, Alexandre de Freitas

Revista do Instituto de Estudos Brasileiros

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jun 2014, N. 58 Pages 135 - 136

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.11606/issn.2316-901X.v0i58p135-136 1292 downloads

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You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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