Os autores relatam caso de paciente com 27 anos de idade com oftalmoplegia externa, anisocoria, ataxia, arreflexia profunda, disfagia, disfonia, paralisia facial periférica bilateral, hipopalestesia e discreta hipoestesia táctil palmo-plantar. O quadro teve início 10 dias após virose de vias aéreas superiores e ocorreu rápida melhora após terapêutica com prednisona. Os achados do exame neurológico e dos subsidiários são compatíveis a alterações centrais e periféricas.

The authors report a case of a 27 year old male patient who has exhibited external ophthalmoplegia, anisocoria, ataxia, absent deep reflexes, dysphagia, dysphonia, bilateral peripheral facial paralysis, hypopallesthesia and a mild sensory impairment of the four extremities. In addition, his cerebrospinal fluid showed albuminocytologic dissociation. The otoneurologic examination showed important findings. These symptoms began ten days after a "cold", and quickly subsided after prednisone therapy. Two months after the onset of clinical features, just a deep apendicular areflexia was detected on his neurological examination. The neurological signs and complementary laboratory findings suggest that both central and peripheral alterations are responsible for the clinical manifestations.