Abstract Introduction: Chronic kidney disease is usually asymptomatic, and its diagnosis depends on laboratory tests, with emphasis on serum creatinine and proteinuria. Objective: To assess knowledge on the role of serum creatinine as a biomarker of kidney function in a sample of the Brazilian population. Method: Cross-sectional observational study conducted in São Paulo (SP, Brazil), in which a random adult population was interviewed. Results: A total of 1138 subjects were interviewed, with a median age of 36 years old (27–52); 55.1% were female. Regarding the “creatinine” biomarker, 40.6% stated they had never performed such a test. When asked about their knowledge on the usefulness of this exam, only 19.6% knew its function. The other responses were “I don’t know” (71.6%), evaluating heart function (0.9%) and liver function (7.8%). Of those who reported they had already taken a creatinine test, only 29.4% correctly identified the role of creatinine. When dividing the groups into “knows” and “does not know” the function of creatinine, a statistically significant difference (p < 0.05) was observed regarding level of education, female sex, being a healthcare student/worker, having ever measured creatinine, knowing someone with kidney disease and older age. In the multivariate analysis, the main variable related to knowing the creatinine role was having previously taken the test (OR 5.16; 95% CI 3.16–8.43, p < 0.001). Conclusion: There is a significant lack of knowledge about creatinine and its use in checkups. The results indicate that greater efforts are needed from healthcare professionals to raise awareness on the role of serum creatinine.

Resumo Introdução: A doença renal crônica costuma ser assintomática e seu diagnóstico depende da realização de exames laboratoriais, com destaque para a creatinina sérica e pesquisa de proteinúria. Objetivo: Avaliar em uma amostra da população brasileira o conhecimento sobre o papel da creatinina sérica como marcador de função renal. Método: Estudo observacional transversal realizado na cidade de São Paulo (SP, Brasil), em que foi entrevistada uma população adulta aleatória. Resultados: Foram entrevistados 1138 indivíduos, com idade mediana de 36 anos (27–52); 55,1% do sexo feminino. Com relação ao marcador “creatinina”, 40,6% afirmaram que nunca realizaram tal dosagem. Quando questionados quanto ao conhecimento sobre a utilidade desse exame, somente 19,6% sabiam a sua função. As outras respostas foram “não sei” (71,6%), avaliar o funcionamento do coração (0,9%) e fígado (7,8%). Dos que afirmaram já terem realizado o exame de creatinina, somente 29,4% acertaram a função da creatinina. Ao dividir os grupos em “sabe” e “não sabe” a função da creatinina, percebeu-se diferença estatisticamente significante (p < 0,05) em relação ao grau de escolaridade, sexo feminino, ser aluno/trabalhador da saúde, ter dosado creatinina alguma vez, conhecer alguém com doença renal e maior idade. Na análise multivariada, a principal variável relacionada com conhecer a função da creatinina foi ter realizado o exame anteriormente (OR 5,16; IC 95% 3,16–8,43, p < 0,001). Conclusão: Há grande desconhecimento sobre a creatinina e seu uso em check-ups. Os resultados indicam que é necessário maior esforço por parte dos profissionais de saúde para divulgar o papel da creatinina sérica.

SUMMARY OBJECTIVE: The aim of this study was to evaluate the prevalence of early neonatal sepsis in pregnant women with a positive culture for group B beta-hemolytic Streptococcus in a middle-income city in Southeastern Brazil. METHODS: A retrospective cohort study was conducted, involving singleton low- and high-risk pregnancies in whom group B beta-hemolytic Streptococcus cultures were evaluated between 35 and 37 weeks of gestation using vaginal and anal swabs. A specific medium (Todd-Hewitt) was used for culturing. The pregnant women were divided into two groups based on positive (n==201) and negative (n==420) cultures for group B beta-hemolytic Streptococcus. RESULTS: The maternal colonization rate by group B beta-hemolytic Streptococcus was 32.3%. The prevalence of early neonatal sepsis was 1.0% (2/201) among patients with a positive group B beta-hemolytic Streptococcus culture and 1.9% (8/420) among patients with a negative culture. Among the patients who underwent adequate prophylaxis, crystalline penicillin G was used in 51.9% (54/104), followed by cefazolin in 43.3% (45/104), ampicillin in 3.8% (4/104), and clindamycin in 1.0% (1/104). A model that included prematurity (p==0.001) proved to be an independent risk predictor of early neonatal sepsis [χ2 (1)==15.0, odds ratio: 16.9, 95% confidence interval: 4.7–61.6, p<0.001, Nagelkerke R2==0.157]. CONCLUSION: The prevalence of a positive culture for group B beta-hemolytic Streptococcus was high. However, the prevalence of early neonatal sepsis was low in pregnant women with both positive and negative group B beta-hemolytic Streptococcus cultures and in pregnant women with a positive culture who underwent both adequate and inadequate antibiotic prophylaxis. Prematurity proved to be an independent predictor of early neonatal sepsis, considering the entire study population.

RESUMO Objetivo: identificar ocorrência de surto compatível com escorbuto e fatores de exposição associados aos sinais/sintomas típicos de hipovitaminose, em penitenciária masculina, Ceará, Brasil, 2019-2020. Métodos: estudo de caso-controle populacional; foram utilizados registros clínicos e entrevistas com casos compatíveis - sinais/sintomas iniciados no período - e com controles; realizou-se análise multivariável. Resultados: 62 casos; idade média de 40,6 anos (DP = 10,8); principais sinais/sintomas foram edema e dor em membros inferiores (100,0%), dificuldade para deambular (91,9%), hematoma/equimose em membros inferiores (90,3%), febre (88,7%); identificou-se, como fator de exposição, média de idade > 40 anos (ORa = 1,10; IC95% 1,05;1,17; p-valor = 0,001); e como fatores protetores, trabalho (ORa = 0,11; IC95% 0,03;0,36; p-valor < 0,001) e participação em aulas (ORa = 0,21; IC95% 0,08;0,59; p-valor = 0,003) dentro da penitenciária. Conclusão: surto da penitenciária compatível com escorbuto pelos sinais/sintomas característicos, associados aos fatores identificados; recomendou-se oferta regular de dieta rica em vitamina C para todos os internos e acompanhamento clínico dos casos.

RESUMEN Objetivo: identificar la ocurrencia del brote compatible con escorbuto y los factores de exposición asociados con signos/síntomas típicos de hipovitaminosis que ocurrieron en una penitenciaría masculina en Ceará, Brasil entre 2019-2020. Métodos: estudio poblacional de casos y controles; se utilizaron historias clínicas y entrevistas con casos compatibles, con inicio de signos/síntomas durante el período de estudio, y controles; se realizó análisis multivariable. Resultados: de los 62 casos, edad media fue 40,6 años (DE = 10,8); principales signos/síntomas fueron edema y dolor en miembros inferiores (100,0%), dificultad para caminar (91,9%), hematoma/equimosis en miembros inferiores (90,3%) y fiebre (88,7%); la edad mayor de 40 años se identificó como factor asociado (ORa = 1,10; IC95% 1,05;1,17; p-valor = 0,001); y como factores protectores: trabajo (ORa = 0,11; IC95% 0,03;0,36; p-valor < 0,001) y participación en clases (ORa = 0,21; IC95% 0,08;0,59; p-valor = 0,003) dentro del centro penitenciario. Conclusión: el brote en centro penitenciario fue considerado compatible con escorbuto debido a los signos/síntomas característicos, asociados a los factores identificados; se recomendó oferta regular de dieta rica en vitamina C a todos los internos y seguimiento clínico de los casos.

ABSTRACT Objective: to identify the occurrence of an outbreak compatible with scurvy and exposure factors associated with typical signs/symptoms of hypovitaminosis that occurred in a male penitentiary in Ceará, Brazil between 2019-2020. Methods: this was a population-based case-control study; we used clinical records and interviews with compatible cases - based on sign/symptom onset during the study period - and with controls; we carried out multivariate analysis. Results: out of 62 cases, mean age was 40.6 years (SD = 10.8); main signs/symptoms were edema and pain in the lower limbs (100.0%), difficulty in walking (91.9%), hematoma/ecchymosis in the lower limbs (90.3%) and fever (88.7%); we identified being over 40 years old as an associated factor (aOR = 1.10; 95%CI 1.05;1.17; p-value = 0.001); and as protective factors: working (aOR = 0.11; 95%CI 0.03;0.36; p-value < 0.001) and taking part in classes (aOR = 0.21; 95%CI 0.08;0.59; p-value = 0.003) in the prison. Conclusion: we considered the penitentiary outbreak to be compatible with scurvy due to characteristic signs/symptoms, associated with the identified factors; we recommended regular provision of a diet rich in vitamin C to all male inmates and clinical follow-up of cases.

Abstract Background Cardiovascular risk factors are prognostic factors in coronavirus disease 2019 (COVID-19) and have been scarcely studied in Brazil. Objective The aim of this study was to assess the impact of cardiovascular risk factors on the outcomes of patients admitted for COVID-19. Methods From July 2020 to February 2021, 200 patients from two public hospitals were enrolled. Patients were included if they had typical symptoms or signs of COVID-19, a positive real-time polymerase chain reaction test (RT-PCR) for COVID-19, and an age above 18 years. This is a prospective, observational, and longitudinal study. Data were collected within 24 h of admission. The primary endpoint was a combination of hospital lethality, mechanical ventilation, hemodialysis, or length of hospital stay >28 days. Continuous variables were compared with the Student’s t-test for independent samples or the Mann-Whitney test. For comparisons of proportions, the χ 2 test was applied. ROC curves and survival curves were constructed. Multivariate logistic regression was performed to identify independent predictors of events. The level of significance was 0.05. Results There were 98 (49%) events during the hospital course, and 72 (36%) died in the hospital. Patients with a primary endpoint were older and more likely to have a history of hypertension, diabetes, chronic obstructive pulmonary disease (COPD), and chronic kidney disease (CKD). Vital signs at admission associated with events were diastolic blood pressure, respiratory rate, and oxygen saturation in ambient air (O 2 Sat). Serum creatinine >1.37 mg/dL at admission had a sensitivity of 51.6 and a specificity of 82% to predict the primary endpoint, with an area under the curve (AUC) of 0.68. In multivariate analysis, age, diabetes, CKD, and COPD were independent predictors of the primary endpoint. Age and CKD were independent predictors of in-hospital lethality. Conclusion Cardiovascular risk factors, such as diabetes and CKD, were related to a worse prognosis in patients hospitalized with COVID-19 in this sample from two public hospitals in the state of Rio de Janeiro.

ABSTRACT Thermography proves to be a new concept in measuring the thermogenesis of biological systems, a valuable method for confirming clinical diagnosis discarding subjective analysis and personal criteria. The result of the thermographic evaluation is the subject of qualitative and quantitative analyses. This study aimed to identify the thermal profile of the lower extremities of individuals diagnosed with cardiovascular and endocrine and metabolic diseases in the treatment of ulcerative wounds. A thermographic evaluation was performed from 19 dorsal, plantar, lateral, and medial extremities. In the qualitative analysis, images with and without a wound were divided according to diagnosis. After the division, a checklist was elaborated for the qualitative evaluation of the images. A total of 100 individuals (49 women and 51 men) participated, 65 with cardiovascular disease and 35 with endocrine and metabolic disease. There was a difference in the thermal pattern between the extremities in both diagnoses. The groups presented similar thermographic characteristics with signs of more radiation in the wounds, predominantly with red and white stains. More regions of interest with lesions on the medial foot, lateral, and medial ankle border were observed in individuals with chronic cardiovascular disease. Those with endocrine and metabolic disease presented more regions with lesions in the plantar (forefoot), dorsal, and medial ankle regions. The profile showed a discrepancy in the thermal pattern in the regions of interest of wounded and without wound extremities according to the diagnoses. Signs of wounds emitting high levels of radiation were similar in both groups, but the physiology of the disease and treatment differed.

RESUMEN La termografía es un nuevo procedimiento para la medición de la termogénesis de los sistemas biológicos y un método valioso para confirmar el diagnóstico clínico que no requiere análisis subjetivos y criterios personales. El resultado de la evaluación termográfica está sujeto a dos análisis: cualitativo y cuantitativo. El objetivo de este estudio fue identificar el perfil térmico de los miembros inferiores en individuos con diagnóstico de enfermedades endocrinometabólicas y circulatorias en tratamiento por lesiones ulcerativas. Para ello, se realizó una evaluación termográfica de 19 regiones, distribuidas en las regiones dorsal, plantar, lateral y medial de los miembros. En el análisis cualitativo, las imágenes con y sin lesiones se dividieron por diagnóstico. Después de la división, se elaboró una lista de verificación para la evaluación cualitativa de las imágenes. Participaron 100 individuos (49 mujeres y 51 hombres), de los cuales 65 tenían enfermedad circulatoria y 35 enfermedad endocrinometabólica. Hubo una diferencia en el estándar de color entre los miembros en ambos diagnósticos. Los grupos mostraron características termográficas similares, con signos de hiperradiación en las lesiones, predominantemente de colores rojo y blanco. Se observó un mayor número de lesiones en el borde medial del pie y en el lateral y medial del tobillo en individuos con enfermedad circulatoria. Aquellos con enfermedad endocrinometabólica presentaron mayor número de lesiones en la región plantar (antepié), dorsal y medial del tobillo. El perfil reveló discrepancia en el color en las regiones de interés de los miembros con y sin lesiones según los diagnósticos. Aunque los signos de hiperradiación de las lesiones fueron similares en ambos grupos, la fisiología de las enfermedades y los tratamientos difirieron.

RESUMO A termografia revela-se como um novo conceito na mensuração da termogênese de sistemas biológicos e um método valioso para confirmação de diagnóstico clínico que dispensa análises subjetivas e critérios pessoais. O resultado da avaliação termográfica é alvo de duas análises: qualitativa e quantitativa. O objetivo deste estudo foi identificar o perfil térmico das extremidades inferiores de indivíduos diagnosticados com doenças de base endocrinometabólica e circulatória em tratamento de feridas ulcerativas. Para tanto, foi realizada avaliação termográfica de 19 regiões, distribuídas nas áreas dorsal, plantar, lateral e medial das extremidades. Na análise qualitativa, as imagens com e sem ferida foram divididas de acordo com o diagnóstico. Após a divisão, elaborou-se um checklist para a avaliação qualitativa das imagens. Participaram 100 indivíduos (49 mulheres e 51 homens), sendo 65 com doença circulatória e 35 com doença endocrinometabólica. Houve diferença no padrão de coloração entre as extremidades em ambos os diagnósticos. Os grupos apresentaram características termográficas semelhantes, com sinais de hiperradiação nas feridas, predominantemente de colorações vermelho e branco. Foi observado maior número de lesões na borda medial de pé e na lateral e medial de tornozelo nos indivíduos com doença de base circulatória. Já aqueles com doença de base endocrinometabólica apresentaram maior número de lesões nas regiões plantar (antepé), dorsal e medial de tornozelo. O perfil revelou discrepância na coloração das regiões de interesse da extremidade com e sem ferida, de acordo com os diagnósticos. Os sinais de hiperradiação das feridas foram semelhantes nos dois grupos, porém a fisiologia das doenças e os tratamentos diferiram.

ABSTRACT Objective: to identify the occurrence of an outbreak compatible with scurvy and exposure factors associated with typical signs/symptoms of hypovitaminosis that occurred in a male penitentiary in Ceará, Brazil between 2019-2020. Methods: this was a population-based case-control study; we used clinical records and interviews with compatible cases - based on sign/symptom onset during the study period - and with controls; we carried out multivariate analysis. Results: out of 62 cases, mean age was 40.6 years (SD = 10.8); main signs/symptoms were edema and pain in the lower limbs (100.0%), difficulty in walking (91.9%), hematoma/ecchymosis in the lower limbs (90.3%) and fever (88.7%); we identified being over 40 years old as an associated factor (aOR = 1.10; 95%CI 1.05;1.17; p-value = 0.001); and as protective factors: working (aOR = 0.11; 95%CI 0.03;0.36; p-value < 0.001) and taking part in classes (aOR = 0.21; 95%CI 0.08;0.59; p-value = 0.003) in the prison. Conclusion: we considered the penitentiary outbreak to be compatible with scurvy due to characteristic signs/symptoms, associated with the identified factors; we recommended regular provision of a diet rich in vitamin C to all male inmates and clinical follow-up of cases.

RESUMEN Objetivo: identificar la ocurrencia del brote compatible con escorbuto y los factores de exposición asociados con signos/síntomas típicos de hipovitaminosis que ocurrieron en una penitenciaría masculina en Ceará, Brasil entre 2019-2020. Métodos: estudio poblacional de casos y controles; se utilizaron historias clínicas y entrevistas con casos compatibles, con inicio de signos/síntomas durante el período de estudio, y controles; se realizó análisis multivariable. Resultados: de los 62 casos, edad media fue 40,6 años (DE = 10,8); principales signos/síntomas fueron edema y dolor en miembros inferiores (100,0%), dificultad para caminar (91,9%), hematoma/equimosis en miembros inferiores (90,3%) y fiebre (88,7%); la edad mayor de 40 años se identificó como factor asociado (ORa = 1,10; IC95% 1,05;1,17; p-valor = 0,001); y como factores protectores: trabajo (ORa = 0,11; IC95% 0,03;0,36; p-valor < 0,001) y participación en clases (ORa = 0,21; IC95% 0,08;0,59; p-valor = 0,003) dentro del centro penitenciario. Conclusión: el brote en centro penitenciario fue considerado compatible con escorbuto debido a los signos/síntomas característicos, asociados a los factores identificados; se recomendó oferta regular de dieta rica en vitamina C a todos los internos y seguimiento clínico de los casos.

RESUMO Objetivo: identificar ocorrência de surto compatível com escorbuto e fatores de exposição associados aos sinais/sintomas típicos de hipovitaminose, em penitenciária masculina, Ceará, Brasil, 2019-2020. Métodos: estudo de caso-controle populacional; foram utilizados registros clínicos e entrevistas com casos compatíveis - sinais/sintomas iniciados no período - e com controles; realizou-se análise multivariável. Resultados: 62 casos; idade média de 40,6 anos (DP = 10,8); principais sinais/sintomas foram edema e dor em membros inferiores (100,0%), dificuldade para deambular (91,9%), hematoma/equimose em membros inferiores (90,3%), febre (88,7%); identificou-se, como fator de exposição, média de idade > 40 anos (ORa = 1,10; IC95% 1,05;1,17; p-valor = 0,001); e como fatores protetores, trabalho (ORa = 0,11; IC95% 0,03;0,36; p-valor < 0,001) e participação em aulas (ORa = 0,21; IC95% 0,08;0,59; p-valor = 0,003) dentro da penitenciária. Conclusão: surto da penitenciária compatível com escorbuto pelos sinais/sintomas característicos, associados aos fatores identificados; recomendou-se oferta regular de dieta rica em vitamina C para todos os internos e acompanhamento clínico dos casos.

ABSTRACT The aimed of this study to assess the productivity and nutritional characteristics of hydroponic corn forage derived from bico de ouro creole seeds and AL-Bandeirante. Two treatments (T), each representing a corn seed variety, were randomly allocated to beds filled with a wood sawdust substrate: T1 (n=5) - bico de ouro creole seed variety, and T2 (n=5) - AL-Bandeirante hybrid seed variety. On the 13th day, forage was collected to assess seedling biometry, green and dry mass production, and bromatological analyses. The data were subjected to statistical analysis, with a 5% significance level. The creole seed variety yielded higher seedling height (17.53 cm), root length (10.19 cm), stem (5.37 cm), leaf (12.17 cm), and greater production of green mass (7.22 kg/m²) and dry matter (2.05kg/m²) (P<0.05). The AL-Bandeirante corn forage had higher dry matter content (39.18%), mineral matter (2.33%), non-fiber carbohydrate (31.88%), and estimated total digestible nutrients (68.14%) (P<0.05), while the creole corn forage had higher organic matter content (99.45%), ethereal extract (19.53%), neutral detergent fiber (45.56%), and cellulose (15.46%) (P<0.05). Crude protein, acid detergent fiber, and lignin were similar between the treatments (P>0.05). Despite the AL-Bandeirante variety yielding a higher concentration of certain nutrients, its forage productivity was significantly low. Therefore, under the conditions of this study, the use of the creole seed variety is recommended.

RESUMO O objetivo com este estudo foi avaliar a produtividade e as características nutricionais da forragem hidropônica de milho derivada de sementes de crioulo bico de ouro e AL-Bandeirante. Dois tratamentos (T), cada um representando uma variedade de semente de milho, foram distribuídos aleatoriamente em canteiros preenchidos com substrato de serragem de madeira: T1 (n=5) - variedade de semente crioula bico de ouro e T2 (n=5) - AL-Bandeirante variedade de semente híbrida. No 13º dia foi coletada forragem para avaliação da biometria das plântulas, produção de massa verde e seca e análises bromatológicas. Os dados foram submetidos à análise estatística, com nível de significância de 5%. A variedade de semente crioula proporcionou maior altura de plântula (17,53 cm), comprimento de raiz (10,19 cm), caule (5,37 cm), folha (12,17 cm) e maior produção de massa verde (7,22 kg/m²) e matéria seca (2,05kg /m²) (P<0,05). A forragem de milho AL-Bandeirante apresentou maior teor de matéria seca (39,18%), matéria mineral (2,33%), carboidrato não fibroso (31,88%) e nutrientes digestíveis totais estimados (68,14%) (P<0,05), enquanto a forragem de milho crioulo apresentou maior teor de matéria orgânica (99,45%), extrato etéreo (19,53%), fibra em detergente neutro (45,56%) e celulose (15,46%) (P<0,05). Proteína bruta, fibra em detergente ácido e lignina foram semelhantes entre os tratamentos (P>0,05). Apesar da variedade AL-Bandeirante apresentar maior concentração de alguns nutrientes, a produtividade de forragem foi significativamente baixa. Portanto, nas condições deste estudo, recomenda-se o uso da variedade crioula de sementes.

ABSTRACT Objective The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development. In Brazil, indigenous people are vulnerable to infections, and few studies have described the health and disease conditions of this population. This study aimed to provide reference values for immunological cell subsets in indigenous Brazilians living in the state of Mato Grosso do Sul. Methods Flow cytometry and 4-color combinations of monoclonal antibodies were used to characterize cells. A total of 115 healthy adults, mostly females (72%), were included in the study. The results are presented as mean and median (2.5%-97.5% percentiles) for T and B lymphocytes, CD4+ T cells, CD8+ T cells, Natural Killer cells, monocytes, and dendritic cells, providing an average immunological profile for the population in question. Results The relative medians of CD3+, CD4+, and CD8+ T cells were significantly higher in women than in men in a healthy indigenous population. Conclusion To our knowledge, cell reference data from indigenous Brazilians are unknown in the literature. The immune cell results presented in this pioneering study will contribute to the clinical and laboratory evaluation of the Brazilian indigenous population, especially given the important differences when compared with other Brazilian ethnic groups.

ABSTRACT Objective The radiological and functional lung sequelae in COVID-19 survivors remain unclear. We compared the chest computed tomography findings of COVID-19 patients with normal and abnormal pulmonary function test results in the post-recovery phase. Methods The data of consecutive patients who underwent pulmonary function tests and chest computed tomography within 14 days after recovery from COVID-19 at two medical centers between May and October 2020 were collected retrospectively. Two thoracic radiologists who were blinded to the clinical information and pulmonary function test results classified the patients according to the computed tomography features, evidence of fibrotic-like changes, and semi-quantitative quantification of the extent of pulmonary abnormalities. The clinical characteristics and computed tomography findings of patients with normal pulmonary function test results were compared with those of patients with abnormal results. Results A total of 101 COVID-19 survivors, comprising 48 ambulatory and 53 hospitalized patients, were included at a median of 95 days from initial symptom onset. Computed tomography revealed fibrotic-like changes in 10.9% of patients. A reduction in the diffusion capacity of carbon monoxide was the most common lung function abnormality (19.8%). Abnormal diffusion capacity of carbon monoxide was associated with the presence and extension of lung opacities on chest computed tomography scans and fibrotic pulmonary abnormalities. The sensitivity, specificity, and accuracy of reduced diffusion capacity of carbon monoxide for detecting fibrotic-like pulmonary changes on chest computed tomography scans were 72.7%, 87.8%, and 86.1%, respectively. Conclusion Our study suggests that the presence of an abnormal diffusion capacity of carbon monoxide in the post-recovery phase of COVID-19 is associated with a greater risk of long-term parenchymal lung disease, as evidenced by the presence of fibrotic-like changes on chest computed tomography scans, such as traction bronchiectasis and architectural distortion.

Abstract This paper aims to discuss the issue of diversity from its incorporation into the training of health professionals through the analysis of the National Curriculum Guidelines (DCN) of two Brazilian undergraduate health courses: medicine and psychology. Thus, it debates the concept of diversity from the contribution of the social sciences, considering the multiple concepts in the nature of social and cultural differences, breaking with essentialist concepts of difference. Reflecting on how diversity appears in the curricular guidelines of these courses, it analyzes from recent studies how this has been considered in training and the main challenges. Intersectionality is an essential political theoretical framework to apprehend the articulation of multiple differences and inequalities acting in a dynamic, fluid, and flexible way from particular historical contexts. Thus, it is sensitive to address the issue of diversity in the training of health professionals. We highlight the importance of studying differences, suggesting an analytical framework that articulates discourses, practice, subjectivation, and social relationships.

Resumo O artigo tem como objetivo discutir a questão da diversidade a partir da sua incorporação na formação dos profissionais de saúde por meio da análise das Diretrizes Curriculares Nacionais (DCN) de dois cursos de graduação na área da saúde no Brasil: medicina e psicologia. Para isso, problematiza a questão da diversidade a partir da contribuição das ciências sociais, ao considerar as múltiplas noções presentes na natureza das diferenças sociais e culturais, rompendo com conceitos essencialistas de diferença. Reflete-se sobre como a diversidade está presente nas diretrizes curriculares desses cursos e, a partir de trabalhos recentes, analisa-se como a diversidade tem sido contemplada na formação, bem como os principais desafios colocados. A interseccionalidade é considerada um referencial teórico político importante para apreender a articulação de múltiplas diferenças e desigualdades que atuam de forma dinâmica, fluida e flexível a partir de contextos históricos particulares, sendo nesse sentido sensível para abordar a questão da diversidade na formação dos profissionais de saúde. Destaca-se a importância de realizar uma análise das diferenças, sugerindo um quadro analítico que articule discursos e práticas, formas de subjetivação e relações sociais.

Resumo O artigo tem como objetivo discutir a questão da diversidade a partir da sua incorporação na formação dos profissionais de saúde por meio da análise das Diretrizes Curriculares Nacionais (DCN) de dois cursos de graduação na área da saúde no Brasil: medicina e psicologia. Para isso, problematiza a questão da diversidade a partir da contribuição das ciências sociais, ao considerar as múltiplas noções presentes na natureza das diferenças sociais e culturais, rompendo com conceitos essencialistas de diferença. Reflete-se sobre como a diversidade está presente nas diretrizes curriculares desses cursos e, a partir de trabalhos recentes, analisa-se como a diversidade tem sido contemplada na formação, bem como os principais desafios colocados. A interseccionalidade é considerada um referencial teórico político importante para apreender a articulação de múltiplas diferenças e desigualdades que atuam de forma dinâmica, fluida e flexível a partir de contextos históricos particulares, sendo nesse sentido sensível para abordar a questão da diversidade na formação dos profissionais de saúde. Destaca-se a importância de realizar uma análise das diferenças, sugerindo um quadro analítico que articule discursos e práticas, formas de subjetivação e relações sociais.

Abstract This paper aims to discuss the issue of diversity from its incorporation into the training of health professionals through the analysis of the National Curriculum Guidelines (DCN) of two Brazilian undergraduate health courses: medicine and psychology. Thus, it debates the concept of diversity from the contribution of the social sciences, considering the multiple concepts in the nature of social and cultural differences, breaking with essentialist concepts of difference. Reflecting on how diversity appears in the curricular guidelines of these courses, it analyzes from recent studies how this has been considered in training and the main challenges. Intersectionality is an essential political theoretical framework to apprehend the articulation of multiple differences and inequalities acting in a dynamic, fluid, and flexible way from particular historical contexts. Thus, it is sensitive to address the issue of diversity in the training of health professionals. We highlight the importance of studying differences, suggesting an analytical framework that articulates discourses, practice, subjectivation, and social relationships.

RESUMO A mastopexia é a cirurgia plástica responsável pela correção da ptose mamária, problema caracterizado pela discrepância entre o volume da mama e sua camada cutânea. As complicações mais relatadas no pós-operatório imediato são deiscência de suturas, seroma, edema e infecção, enquanto outras, como a galactorreia, são consideradas raras. O caso em questão consiste em uma paciente de 52 anos, que realizou a mastopexia bilateral com inclusão de prótese e desenvolveu após 30 dias do procedimento galactorreia com hiperprolactinemia. O diagnóstico foi suspeitado devido ao aumento de volume, associado a dor ou desconforto mamário no pós-operatório, seguido de saída secreção leitosa. A galactocele pós-mastopexia com prótese pode ou não estar associada à hiperprolactinemia, porém pouco se sabe sobre a real fisiopatologia do desenvolvimento desse quadro. O tratamento foi feito com cabergolina 0,5mg em duas doses, com melhora do quadro.

ABSTRACT Mastopexy is the plastic surgery responsible for correcting breast ptosis, a problem characterized by a discrepancy between the volume of the breast and its skin layer. The complications most commonly reported in the immediate postoperative period are suture dehiscence, seroma, edema and infection, while others such as galactorrhea are considered rare. The case in question consists of a 52-year-old patient who underwent bilateral mastopexy with prosthesis inclusion and developed galactorrhea with hyperprolactinemia 30 days after the procedure. The diagnosis was suspected of increased volume, associated with postoperative breast pain or discomfort, followed by milky discharge. Galactocele after mastopexy with a prosthesis may or may not be associated with hyperprolactinemia, but little is known about the real pathophysiology of the development of this condition. Treatment was done with cabergoline 0.5mg in two doses, improving the condition.

ABSTRACT Introduction: Advanced nursing practice presents an expanded scope that seeks to respond to patient problems in a specific clinical area. Objective: To identify, from among the functions declared as advanced practice at the international level, those performed by the nursing personnel in mother and infant care at the first level. Methods: A cross-sectional and descriptive study was carried out in Villa Clara, Cuba, between February and December 2021. The study universe was made up of 671 graduates. Through probabilistic sampling with 95 % of reliability, a sample was selected, consisting of 326 nurses working in the 35 polyclinics of the province and in charge of the Mother and Infant Care Program. An advanced practice nurse role delineation instrument was applied. The calculations were made corresponding to the average number of functions grouped by domains, standard deviation, and the coefficient of variation between its items; as well as Cronbach's alpha and an index establishing a correlation between the items for measuring the internal consistency of the scale by dimensions and globally. Results: All the domains are above the indicator established for each dimension accrediting it as advanced practice. No domain was found with a low index; all six maintained a validity and reliability above 0.5. The internal consistency obtained using Cronbach's alpha was high. Conclusions: The internationally recognized advanced practice functions are performed by the nurses, included in the study as part of their daily practice, since the different domains of the instrument reached values above the established indicator.

RESUMEN Introducción: La Práctica Avanzada de Enfermería constituye una práctica con alcance expandido, que busca responder a problemáticas de los pacientes en un área clínica específica. Objetivo: Identificar de las funciones declaradas práctica avanzada a nivel internacional, las que realiza el personal de enfermería de la atención materna infantil en el primer nivel de atención. Métodos: Estudio descriptivo transversal, en Villa Clara, Cuba, entre febrero y diciembre del 2021. Universo de 671 licenciados, muestreo probabilístico con un 95 % de confiabilidad de la muestra seleccionada, con 326 enfermeros que laboran en los 35 policlínicos y atienden el programa Materno Infantil. Se aplicó el instrumento de definición del rol de Enfermera de Práctica Avanzada, se calculó el promedio de las funciones agrupadas por dominios, la desviación estándar y coeficiente de variación entre sus ítems; el Alfa de Cronbach y un índice, que estableció correlación entre los ítems para medir consistencia interna de la escala por dimensiones y a nivel global. Resultados: El total de los dominios se encuentra por encima del indicador establecido para cada dimensión que la acredita como práctica avanzada. No se encontró ningún dominio con el índice bajo, los seis mantuvieron una validez y fiabilidad por encima de 0,5. La consistencia interna por alfa de Cronbach obtenida fue alta. Conclusiones: Las funciones de práctica avanzada reconocidas a nivel internacional se ejecutan por las enfermeras, incluidas en el estudio en su práctica diaria, en tanto los diferentes dominios del instrumento alcanzaron valores superiores al indicador establecido.

The acquired immunodeficiency syndrome (AIDS) is a disease which effects the immune system and, to reduce the development of this pathology, antiretrovirals was created. Evidences demonstrate the effectiveness of Pre-Exposure Prophylaxis (PrEP), however, it still has obstacles, such as the lack of knowledge, technique and training of health professionals for patient guidance and prescription. The aim of this research is to investigate the subjective and objective knowledge of PrEP, futhermore the number of prescriptions in State of Goiás. For data collection, a survey was applied to 152 physicians with active enrollment in Conselho Regional de Medicina do Estado de Goiás. As a result, 132 physicians (86,8%) reported having previous knowledge about PrEP, on average of 44,2% informed having knowledge for prescription, 129 (84,8%) never prescribed PrEP and, when objectively evaluated, on average of 83,8% have knowledge about the risk categorization for the drug use. The outcome of this research is not consonant with the hypothesis that only 20% of the physicians would have plenty knowledge, according to the literature, but it is evident the need for medical training to optimize the clinical impact on public health of this important HIV prevention strategy.

A Síndrome da Imunodeficiência Adquirida é uma infecção que acomete o sistema imunológico e, para redução da propagação dessa patologia, desenvolveu-se os antirretrovirais. Evidências demonstram a eficácia da Profilaxia Pré-Exposição (PrEP), mas ainda com obstáculos, como a falta de conhecimento, técnica e treinamento dos profissionais de saúde para a sua orientação e prescrição. O objetivo dessa pesquisa é investigar o conhecimento subjetivo, objetivo e prescrição da PrEP por médicos do Estado de Goiás. Para a coleta de dados foi aplicado um questionário à 152 médicos com inscrição ativa no Conselho Regional de Medicina do Estado de Goiás. Como resultado, 132 médicos (86,8%) afirmaram possuir conhecimento prévio sobre a PrEP, em média 44,2% informaram ter conhecimento para prescrição, 129 (84,8%) nunca prescreveram PrEP e, quando avaliado objetivamente, em média 83,8% possuem conhecimento sobre a categorização de risco para o uso do medicamento. Os resultados dessa pesquisa não estão em consonância com a hipótese de que apenas 20% dos médicos teriam conhecimento suficiente, de acordo com a literatura, mas é evidente a necessidade de capacitação médica visando otimizar o impacto clínico na saúde pública desta importante estratégia de prevenção do HIV.

Abstract Aim: The purpose of this paper was to analyze the internal consistency of the Sport Motivation Scale-II (SMS-II) questionnaire based on three studies with sports practitioners in the Brazilian college context. Methods: All the three studies i) were carried out with students enrolled in higher education and engaged in sports training by their institution (n1 = 304; n2 = 441; n3 = 310); ii) used SMS-II as an instrument for data collection; iii) used the online procedure for data collection. The Confirmatory Factor Analysis was performed and Cronbach's Alpha (α), McDonald's Omega (Ω), and the correlation between items were used to assess internal consistency. Results: As potentialities, five dimensions of the SMS-II presented high values of internal reliability (α and Ω > 0.60). As a limitation, the dimension of introjected regulation showed low reliability (α and Ω < 0.40) in the three studies conducted by our group. The exclusion of item 16 enabled an increase in alpha, but without achieving satisfactory reliability in Study 1 (α = 0.46) and Study 2 (α = 0.31). In Study 3, the exclusion of item 7 improved the internal reliability of the dimension (α = 0.43) also without reaching satisfactory values of internal consistency. It was not possible to identify a problematic item, given that each item had a different influence in the three studies. Conclusion: We found good values of validity and internal consistency for the Brazilian version of the SMS-II. However, we suggest attention to the introjected regulation dimension when using the instrument in the Brazilian college context.