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MESENCHYMAL CELLS IN ROTATOR CUFF REPAIR - TECHNIQUE DESCRIPTION AND CASE REPORTS
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MALAVOLTA, EDUARDO ANGELI

; MICELI, VINICIUS LAMBOGLIA

; ASSUNÇÃO, JORGE HENRIQUE

; ANDRADE-SILVA, FERNANDO BRANDAO

; GRACITELLI, MAURO EMILIO CONFORTO

; TATSUI, NELSON HIDEKAZU

; ESPIRANDELLI, LUIZ CÉSAR

; FERREIRA NETO, ARNALDO AMADO

Acta Ortopédica Brasileira

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2023, Volume 31 N. 6 elocation e268392

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To describe a protocol of obtention of mesenchymal stem cells and to report their use as a biological adjuvant in three patients undergoing arthroscopic rotator cuff repair. Methods: Case series of patients who underwent arthroscopic repair of isolated full-thickness supraspinatus tear using mesenchymal stem cells obtained from the bone marrow as a biological adjuvant. All patients were operated on at the same institution, by a surgeon with 13 years of experience. The cells were applied at the end of the procedure, at the tendon-bone interface, at an approximate concentration of 2,000,000 mesenchymal cells/mm3 and a total volume of 5 ml. Results: All patients improved with the procedure, with one excellent and two good results. All cases overcame the minimally important clinical difference. All cases reached tendon healing, without partial or complete re-tears. We observed no complications. Conclusion: Arthroscopic rotator cuff repair with added mesenchymal cells obtained from bone marrow and submitted to a cell expansion process led to good functional results and healing in all cases in the sample, with no complications. Level of Evidence IV, Case Series.

RESUMO Objetivo: Descrever o protocolo de obtenção de células mesenquimais e relatar seu uso como adjuvante biológico em três pacientes submetidos ao reparo artroscópico do manguito rotador. Métodos: Série de casos de pacientes submetidos ao reparo artroscópico de rotura transfixante do músculo supraespinal utilizando como adjuvante biológico células mesenquimais obtidas da medula óssea. Todos ospacientes foram operados na mesma instituição por um cirurgião com 13 anos de experiência. As células foram aplicadas ao final do procedimento, na interface do tendão com o osso, na concentração aproximada de 2 milhões de células mesenquimais/mm3 e volume total de 5 ml. Resultados: Todos os pacientes melhoraram após o procedimento, havendo um resultado excelente e dois bons. Todos superaram a diferença clínica minimamente importante. Em todos os casos ocorreu cicatrização tendínea, sem a presença de rerroturas parciais ou completas. Não observamos complicações. Conclusão: O reparo do manguito rotador artroscópico com adição de células mesenquimais obtidas da medula óssea e submetidas a processo de expansão celular levou a bons resultados funcionais e cicatrização, sem complicações, em todos os casos da amostra. Nível de Evidência IV, Série de Casos.

https://doi.org/10.1590/1413-785220233105e268392

Caracterização microestrutural de uma liga Fe-7,1Al-0,7Mn-0,4C-0,3Nb do sistema Fe-Mn-Al-C
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Gurgel, Mônica Aline Magalhães

; Baêta Júnior, Eustáquio de Souza

; Teixeira, Rodolfo da Silva

; Moreira, Luciano Pessanha

; Paulo Brandao, Luiz

; Paula, Andersan dos Santos

Matéria (Rio de Janeiro)

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2022, Volume 27 N. 2 elocation e202146400

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Nos últimos anos, vários estudos foram realizados buscando reduzir o peso de veículos automotores, a fim de diminuir as emissões de poluentes. Neste cenário os aços de baixa densidade do sistema Fe-Mn-Al-C podem ser considerados uma alternativa promissora para suprir essas exigências da indústria automotiva. Geralmente, nos aços de baixa densidade, uma quantidade considerável de alumínio é adicionada a fim de reduzir a densidade geral do aço. No entanto, altos teores de alumínio promovem características distintas na microestrutura, destes aços quando comparados aos aços convencionais, como a presença do carboneto k ((Fe, Mn)3AlC), além da necessidade de se entender a combinação deste elemento com outros elementos de liga que podem ser adicionados. Neste contexto, este trabalho tem como objetivo avaliar a microestrutura, a dureza e a densidade resultantes em função da influência do Al e do Nb em uma nova composição química pertencente ao sistema Fe-Mn-Al-C, na condição trabalhada a quente, a partir de análises de difração de raios X, microscopia eletrônica, medidas de dureza e densidade por princípio de Arquimedes. Os resultados permitiram indicar que o alto teor de Al adicionado promoveu uma redução de cerca de 13% na densidade, em relação aos aços estruturais tradicionais, e a estabilidade da ferrita δ até a temperatura ambiente. A condição avaliada apresentou a temperatura ambiente uma microestrutura formada por uma matriz de ferrita δ e α, juntamente com precipitados de carboneto k (AlFe3C) e carboneto de nióbio (NbC), estes dois últimos devido as adições de Al e Nb, resultando em uma dureza de 59,4 ± 1 HRA e uma estimativa do limite de resistência a tração de próximo a 800 MPa – dentro da faixa dos aços avançados de alta resistência (Advanced High Strenght Steels – AHSS).

ABSTRACT In recent years, several studies have been carried out seeking to reduce the weight of motor vehicles to reduce pollutant emissions. In this scenario, low-density steels from the Fe-Mn-Al-C system can be considered a promising alternative to meet these requirements of the automotive industry. Generally, in low-density steel, a considerable aluminum amount is added in order to reduce the overall density of the steel. However, high aluminum contents promote distinct characteristics in the microstructure of these steels when compared to conventional steels, such as the k carbide presence ((Fe,Mn)3AlC), in addition to the need to understand the combination of this element with other alloying elements that can be added. In this context, this paper aims to evaluate the resulting microstructure, hardness and density as a function of the Al and Nb influence in a new chemical composition belonging to the Fe-Mn-Al-C system, in hot worked condition from X-ray diffraction and eletron microscopy analyses, hardness, and density measurements by Archimedes’ principle. The results indicated that the high added Al promoted a reduction of about 13% in density, in relation to typical structural steels, and the δ ferrite stability up to room temperature. The condition evaluated at room temperature presented a microstructure formed by a matrix with δ and α ferrite, together with k-carbide (AlFe3C) and niobium carbide (NbC) precipitates, the latter two due to the Al and Nb additions, resulting in 59.4 ± 1 HRA hardness and an estimated tensile strength limit close to 800 MPa – within the range of the Advanced High Strength Steels (AHSS).

https://doi.org/10.1590/1517-7076-rmat-2021-46400

Experimental and Analytical Investigation on the Effect of Heat Treatment Parameters on the Mechanical Properties of an API 5L X65 Steel
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Moraes, Nicki Robbers Darciano Cajueiro de

; Garcia, Julianna Magalhães

; Baêta Júnior, Eustáquio de Souza

; Cruz, Renato Batista da

; Brandao, Luiz Paulo

Materials Research

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2021, Volume 24 N. 2 elocation e20200503

Abstract: En | Text: En | PDF: En

Abstract High Strength Low Alloy steels (HSLA) for oil and gas pipelines should display high mechanical strength, toughness, ductility and weldability. In this work we studied the influence of quenching and tempering temperature on the yield strength, ultimate tensile strength, percent elongation and hardness of API 5L steel pipes in order to optimize heat treatments to be performed after hot induction bending of the material. The thermal cycles involved soaking temperatures of 880, 920 and 960 °C, cooling water at 15, 23 and 31 °C and tempering at 530, 600 and 670 °C. From this, experimental design techniques were used to reduce the number of experiments. The results from contour maps suggest that soaking temperatures of 910 and 950 °C and tempering between 540 and 610 °C were the most suitable for treatment, regarding mechanical strength. The variation of the water temperature was not significant for the assumed cooling conditions. The prediction regression models of the mechanical properties from the variables involved in the heat treatments showed a good fit between the experimental and predicted results, with correlation coefficient between 0.89 and 0.94.

https://doi.org/10.1590/1980-5373-mr-2020-0503 348 downloads

Residual Stress Analysis After the Induced Martensitic Transformation by Rolling and Tensile Test in the 304L TRIP Steel
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Alves, Juciane Maria

; Paula, Andersan dos Santos

; Brandao, Luiz Paulo

Materials Research

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2021, Volume 24 N. 4 elocation e20210156

Abstract: En | Text: En | PDF: En

Abstract In this work, the residual stress study by XRD was carried out after martensitic transformation of a 304L steel subjected to plastic strain by rolling and tensile test, at room and cryogenic temperatures. This article intents to contribute with the understanding of residual stresses generated by martensitic transformation induced by plastic deformation due to its complexity. From the experimental conditions employed, it was possible to obtain high martensite volumetric fraction and it was possible to observe the influence of existing phases on the performance of residual stress measurements. In general, compressive residual stress was observed for both austenite and martensite phases. The samples rolled at cryogenic temperature showed higher magnitudes of compressive stresses, between -123 and -231 MPa, for martensite volumes between 98 and 100%. It was also clearly displacement and widening of diffraction line due to the presence of residual macro and microstresses when compared to the as-received material.

https://doi.org/10.1590/1980-5373-mr-2021-0156 89 downloads

Avaliação da termoablação com endolaser da veia safena parva com anestesia local
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Souza, Filipe Cézar Bertassoni de

; Araujo, Walter Jr. Boim de

; Brandao, Adriana Buechner de Freitas

; Mazzoni, Camila de Almeida

; Erzinger, Fabiano Luiz

; Caron, Filipe Carlos

; Ruggeri, Viviane Gomes Milgioransa

Jornal Vascular Brasileiro

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2021, Volume 20 elocation e20200215

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Contexto Na insuficiência venosa crônica (IVC), a veia safena parva (VSP) é afetada em 15% dos casos. A cirurgia convencional é a técnica padrão para o tratamento da insuficiência da VSP, sendo a lesão no nervo sural uma complicação bastante temida. O tratamento de termoablação com endolaser tende a ser um método cirúrgico que diminui complicações da terapia cirúrgica da IVC. Objetivos Avaliar os pacientes com IVC submetidos à terapia por endolaser da VSP ao menos 30 dias após o procedimento. Métodos Foram analisados 54 membros inferiores de 46 pacientes submetidos à terapia por endolaser 1470 nm, sob anestesia local, para o tratamento da IVC em um hospital terciário. Os pacientes foram avaliados no período pré-operatório, intraoperatório e pós-operatório de 30 dias, através da clínica, exame físico e achados ecográficos. Resultados Nos 54 membros inferiores submetidos ao tratamento, comparando-se o período pré-operatório e o 30º dia pós-operatório, houve diferença significativa (p < 0,003) na redução do diâmetro da VSP tratada (6,37 mm pré-operatório e 5,15 mm no 30º dia pós-operatório) (IC95% 4,58-5,72) e na melhora do escore de gravidade clínica venosa (VCSS) (média de 8,02 pré-operatório e 6,11 no 30º dia pós-operatório) (IC95% 5,01-7,21) (p < 0,02). Complicações pós-operatórias, como parestesia e flebite, estiveram presentes e foram diagnosticadas em cinco e três pacientes, respectivamente, sem significar alteração na qualidade de vida e nas atividades de rotina. Conclusões A técnica de termoablação com laser da VSP mostrou-se segura e eficaz na redução dos sintomas clínicos e na melhora da qualidade de vida.

Abstract Background The small saphenous vein (SSV) is affected in 15% of chronic venous insufficiency (CVI) cases. Conventional surgery is the standard technique for treatment of SSV insufficiency, but sural nerve injury is a complication of great concern. Endovenous laser ablation is a surgical technique for treatment of CVI that is considered likely to reduce morbidity and mortality. Objectives To evaluate patients with CVI undergoing endovenous laser ablation of the SSV at least 30 days after the procedure. Methods We analyzed 54 lower extremities in 46 patients scheduled for 1470-nm endovenous laser ablation under local anesthesia to treat CVI in a tertiary hospital. Patients were evaluated preoperatively, intraoperatively, and postoperatively over 30 days with clinical examination, physical examination, and ultrasound. Results In the 54 lower extremities treated, there was a significant difference (p < 0.003) in terms of reduction in the diameter of treated veins (6.37 mm preoperatively and 5.15 mm on the 30th postoperative day) and improvement in the venous clinical severity score (VCSS) (means of 8.02 preoperative and 6.11 on the 30th postoperative day) (95%CI, 5.01—7.21) (p < 0.02). Postoperative complications such as paresthesia and phlebitis were present and diagnosed in 5 and 3 patients, respectively, but did not affect their quality of life or routine activities. Conclusions Intravenous laser ablation of the SSV proved to be safe and effective for reducing clinical symptoms and improving quality of life.

https://doi.org/10.1590/1677-5449.200215 5 downloads

Satisfaction and attitudinal responses: indirect effects of involvement and reputation
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Fernandes, Aleixo

; Brandao, Marcelo Moll

; Lopes, Evandro Luiz

; Quevedo-Silva, Filipe

RAUSP Management Journal

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mar 2020, Volume 55 N. 1 Pages 70 - 85

Abstract: En | Text: En | PDF: En

Abstract Purpose The purpose of this paper is to identify the influence of the company’s reputation and individual consumer involvement in the relationship between satisfaction, loyalty and willingness to pay more for a product. Design/methodology/approach The method used is quantitative, by means of a survey with real consumers of automotive services of two vehicle dealerships, whose data were analyzed through linear regression analysis and conditional analysis of moderation. Findings The authors have identified that the relationship between satisfaction and loyalty and between loyalty and willingness to pay more for a product is entirely moderated by the (high) reputation of the brand and the (high) individual involvement of the consumer. Practical implications The study contributes to marketing managers as it demonstrates effect of brand reputation and involvement. Therefore, it is understood that these variables need to be considered in satisfaction surveys, as it has been proven that satisfaction alone cannot explain the variables of business performance (loyalty and willingness to pay). Originality/value The greatest innovation of this study is the identification of the total moderation between stated satisfaction and loyalty and between satisfaction and willingness to pay more. It has been demonstrated that high levels of brand reputation coupled with high levels of consumer involvement account for the fully dependent variables.

https://doi.org/10.1108/rausp-10-2018-0094 333 downloads

Determination of phases and residual stresses after martensitic transformation induced by rolling in 304L stainless steel
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Alves, Juciane Maria

; Brandao, Luiz Paulo

; Paula, Andersan dos Santos

Matéria (Rio de Janeiro)

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2019, Volume 24 N. 3 elocation e12467

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O aço inoxidável austenítico 304L é suscetível à transformação martensítica induzida por deformação. Esta transformação de fases depende da temperatura, assim como do modo, taxa e nível de deformação. Neste trabalho as fases e tensões residuais de um aço TRIP 304L, em que a transformação martensítica foi induzida por laminação a frio, foram investigadas por difração de raios-X (DRX). As análises foram realizadas em diferentes espessuras das amostras. Os resultados mostraram que a composição de fases e as tensões residuais são fortemente dependentes da espessura das amostras. Todas as amostras apresentaram tensão residual compressiva.

ABSTRACT The 304L austenitic stainless steel is susceptible to deformation induced martensitic transformation. This phase transformation depends on the temperature as well as on the mode, rate and level of deformation. In this work the phases and residual stresses of a 304L TRIP steel where martensitic transformation was induced by cold rolling were investigated by X-ray diffraction XRD. The analyses were performed for different sample thicknesses. The results showed that the phase composition and the residual stresses are strongly dependent on sample thickness. All samples showed a compressive residual stress.

https://doi.org/10.1590/s1517-707620190003.0783 635 downloads

Residual Stress Evaluation by X-Ray Diffraction and Hole-Drilling in an API 5L X70 Steel Pipe Bent by Hot Induction
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Ceglias, Rodrigo Braga

; Alves, Juciane Maria

; Botelho, Ramón Alves

; Baeta Júnior, Eustáquio de Souza

; Santos, Igor Cuzzuol dos

; Moraes, Nicki Robbers Darciano Cajueiro de

; Oliveira, Rebeca Vieira de

; Diniz, Saulo Brinco

; Brandao, Luiz Paulo

Materials Research

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oct 2016, Volume 19 N. 5 Pages 1176 - 1179

Abstract: En | Text: En | PDF: En

The API 5L X70 steel is used in high-pressure gas transmission pipelines. Because of this, knowledge of presence of residual stress and their magnitude is important to assess the material integrity in service. For the pipeline manufacturing, tubes need to be curved which is often made using the hot induction bending process. This process can introduce different residual stress depending of tube position. For this research, in order to evaluate the residual stress, was used an API 5L X70 tube that was previously curved by hot induction process. Samples were taken from the extrados, intrados, neutral line and straight section of the curved tube. Residual stresses were studied by two conventional methods: X-Ray Diffraction (XRD) and Hole-Drilling, which are destructive and non-destructive methods, respectively, in order to assess their qualitative responses. Each of these methods presents particular methodologies in sample preparation and material analysis, but also they differ in factors such time consumption and cost of the analysis. The qualitative responses obtained by the two different methods were comparable and satisfactory and pointed out the existence of a compressive residual stress state in steel pipe.

https://doi.org/10.1590/1980-5373-MR-2016-0012 2412 downloads

Mechanical Properties and Crystallographic Texture of Symmetrical and Asymmetrical Cold Rolled IF Steels
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Sardinha, Nina do Amaral

; Santos, Igor Cuzzuol dos

; Andrade, Bárbara Vaz

; Botelho, Ramón Alves

; Oliveira, Rebeca Vieira de

; Diniz, Saulo Brinco

; Paula, Andersan dos Santos

; Brandao, Luiz Paulo

Materials Research

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oct 2016, Volume 19 N. 5 Pages 1042 - 1048

Abstract: En | Text: En | PDF: En

Abstract The crystallographic texture developed during cold rolling and subsequent annealing of interstitial free sheet steels aims to increase conformability. For this, it is necessary to obtain partial α-fiber and continuous and homogeneous γ-fiber texture components. In this work, the influence of symmetric (SR) and asymmetric (AR) cold rolling on crystallographic texture and mechanical properties of an interstitial free steel (IF) was investigated. Symmetric cold rolling yields α- and γ-fibers, which are enhanced as deformation increases. Moreover, α-fiber weakening occurs due to recrystallizations, improving formability. The same fibers are produced by asymmetric cold rolling, but in this case, the γ-fiber is slightly shifted in psi, which is one of Euler angles second ROE's notation1,2, and more homogeneous than in symmetric rolling. The best mechanical properties were achieved by asymmetric cold rolling/annealed with about 80% deformation.

https://doi.org/10.1590/1980-5373-MR-2015-0449 1745 downloads

10.

Properties of NGO 3% Silicon Steel Asymmetrically Cold Rolled
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Botelho, Ramon Alves

; Diniz, Saulo Brinco

; Cunha, Marco Antonio da

; Brandao, Luiz Paulo

Materials Research

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dec 2015, Volume 18 Pages 143 - 147

Abstract: En | Text: En | PDF: En

The effects of asymmetric and conventional deformations and annealing on the microstructure of non-grain-oriented (NGO) 3 wt% silicon steel were analyzed by x-ray diffraction, optical microscopy and magnetometry. The results suggest that pure asymmetric rolling tends to lessen magnetic losses. However, intermediate annealing resulted in lower planar anisotropy, which could be estimated from the magnetic anisotropy theory. In this work, it was shown that this theory is able to predict the J50 magnetic polarization values using crystallographic texture.

https://doi.org/10.1590/1516-1439.352714 1786 downloads

11.

The Influence of Sample Preparation on the Quantitative Analysis of the Volume Fraction of Martensite Formed in a 304l Trip Steel
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Alves, Juciane Maria

; Brandao, Luiz Paulo

; Paula, Andersan dos Santos

Materials Research

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dec 2015, Volume 18 Pages 159 - 163

Abstract: En | Text: En | PDF: En

The metastable 304L austenitic stainless steels are susceptible to phase transformation induced by plastic deformation. The traditional metallographic preparation, via mechanical methods, introduces superficial plastic deformation from grinding and polishing. It is important to evaluate this effect on the results of quantitative analysis of martensite formed in 304L steels and similar alloys. In this work, phase transformation was induced by a tensile test at room temperature with two different plastic deformation rates in order to provide distinct structural conditions for the proposed analysis. X-ray Diffraction (XRD) and Ferritescopy were used to determine the volume fraction of martensite in samples with and without metallographic preparation. The results show that the analyses quantitative were not affected by metallographic preparation.

https://doi.org/10.1590/1516-1439.347714 1662 downloads

12.

Dislocation Density by X-ray Diffraction in α Brass Deformed by Rolling and ECAE
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Sousa, Talita Gama

; Diniz, Saulo Brinco

; Pinto, André Luiz

; Brandao, Luiz Paulo

Materials Research

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dec 2015, Volume 18 Pages 246 - 249

Abstract: En | Text: En | PDF: En

Dislocations are responsible for most aspects of plastic deformation in metals. In this work, the dislocation density, ρ, in brass was estimated after different deformation processes via line broadening of X-ray diffractograms using the Convolutional Multiple Whole Profile Program (CMWP) and by Transmission Electron Microscopy (TEM). In addition, we attempted to evaluate, on a global basis, the influence of crystallographic texture in ρ analysis, making sure that the results obtained by XRD could be trusted even in samples with moderate levels of texture. For this, we compared the ρ values for α brass samples (66% Cu and 34% Zn) with different levels of texture, one deformed by cold rolling and the other by equal channel angular extrusion (ECAE).The results suggest that using CMWP program it was possible to satisfactorily estimate the dislocation density in α brass. It also the was shown that the results by XRD and by TEM were self-consistent in two samples texturized to different degrees.

https://doi.org/10.1590/1516-1439.369214 3299 downloads

13.

I Posicionamento Brasileiro sobre Pre-Hipertensao, Hipertensao do Avental Branco e Hipertensao Mascarada: Diagnostico e Conduta
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Alessi, Alexandre

; Brandao, Andrea Araujo

; Paiva, Annelise Machado Gomes de

; Nogueira, Armando da Rocha

; Feitosa, Audes

; Gonzaga, Carolina de Campos

; Amodeo, Celso

; Mion, Decio

; Souza, Dilma do Socorro Moraes de

; Barbosa, Eduardo

; Junior, Emilton Lima

; Nobre, Fernando

; Fuchs, Flavio Dani

; Junior, Hilton Chaves

; Schneider, Jamil Cherem

; Gemelli, Joao

; Villela-Martin, Jose Fernando

; Scala, Luiz Cesar Nazario

; Gomes, Marco Antonio Mota

; Malachias, Marcus Vinicus Bolivar

; Morais, Nelson Siqueira de

; Moreira Filho, Osni

; Passarelli Junior, Oswaldo

; Jardim, Paulo Cesar Brandao Veiga

; Miranda, Roberto Dischinger

; Povoa, Rui

; Fuchs, Sandra Cristina

; Baiocchi, Sergio

; Jardim, Thiago Veiga

; Barroso, Weimar Kunz Sebba

Arquivos Brasileiros de Cardiologia

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mar 2014, Volume 102 N. 2 Pages 110 - 119

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20140011 23506 downloads Cited 4 times in SciELO

14.

Pressao Arterial na Adolescencia, Adipocinas e Inflamacao no Adulto Jovem. Estudo do Rio de Janeiro
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Campana, Erika Maria Goncalves

; Brandao, Andrea Araujo

; Pozzan, Roberto

; Magalhaes, Maria Eliane Campos

; Fonseca, Flavia Lopes

; Pizzi, Oswaldo Luiz

; Freitas, Elizabete Viana de

; Brandao, Ayrton Pires

Arquivos Brasileiros de Cardiologia

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jan 2014, Volume 102 N. 1 Pages 60 - 69

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Fundamento: O impacto pressão arterial (PA) na adolescência sobre outros fatores de risco cardiovascular em adultos jovens é importante para a prevenção primária. Objetivo: Avaliar a PA, índices antropométricos, perfil metabólico e inflamatório de jovens estratificados pelo comportamento da sua PA obtida há 18 anos. Métodos: Avaliaram-se 116 indivíduos, sendo 63 homes, pertencentes ao estudo do Rio de Janeiro (seguimento 17,76 ± 1,63 anos) em dois momentos: A1 (12,40 ± 1,49 anos) e A2 (30,09 ± 2,01 anos). Os 116 indivíduos foram divididos em dois grupos: GN (n = 71), PA normal em A1; e GH (n = 45): PA anormal em A1. A PA, o peso, a altura e o índice de massa corporal (IMC) foram obtidos em A1 e A2. Em A2, acrescentaram-se a circunferência abdominal (CA) e variáveis laboratoriais, metabólicas e inflamatórias. Resultados: 1) Os grupos não diferiram quanto à idade e sexo; 2) Em A2, GH apresentou maiores médias de peso, IMC, PA, insulina, HOMA-IR (p < 0,001), leptina (p < 0,02), Apolipoproteína B100 e A1 (p < 0,02), relação Apolipoproteína B100 / Apolipoproteína A1 (p < 0,010), maiores prevalências de sobrepeso/obesidade (p < 0,001), da CA aumentada (p < 0,001) e de hipertensão arterial (p < 0,02); 3) Não houve diferença entre os grupos para as variáveis inflamatórias; 4) Houve correlação positiva da PA em A1 com a PA, o IMC, e com a insulina, a leptina e o HOMA-IR em A2 (p < 0,05). Conclusões: A PA na adolescência se associou a maiores valores de PA, variáveis antropométricas e metabólicas na fase adulta jovem, mas não a variáveis inflamatórias.

Background: The impact of blood pressure (BP) during adolescence on other cardiovascular risk factors in young adults is important for the primary prevention. Objective: To evaluate BP, anthropometric indexes, metabolic and inflammatory profiles in young individuals stratified by their BP behavior recorded for 18 years. Methods: A total of 116 individuals, of whom 63 were males, from the Rio de Janeiro study (follow-up of 17.76 ± 1.63 years), were assessed at two moments: A1 (12.40 ± 1.49 years) and A2 (30.09 ± 2.01 years). The 116 individuals were divided into two groups: GN (n = 71), of participants with normal BP at A1; and GH (n = 45), of those with abnormal BP at A1. BP, weight, height and body mass index (BMI) were measured at A1 and A2. At A2, abdominal circumference (AC) and laboratory, metabolic and inflammatory variables were included. Results: 1) No difference was observed between the groups as regards age and gender; 2) At A2, GH showed higher mean weight, BMI, BP, insulin, HOMA-IR (p < 0.001), leptin (p < 0.02), apolipoprotein B100 and A1 (p < 0.02), apolipoprotein B100 / apolipoprotein A1 ratio (p < 0.010); and higher prevalences of overweight/obesity (p < 0.001), of increased AC (p < 0.001) and of hypertension (p < 0.02); 3) No difference was observed between the groups as regards the inflammatory variables; 4) There was a positive correlation of BP at A1 with BP, BMI, insulin, leptin and HOMA-IR at A2 (p < 0.05). Conclusion: BP in adolescence was associated with higher values of BP, and anthropometric and metabolic variables in young adulthood, but not with inflammatory variables.

https://doi.org/10.5935/abc.20130226 4638 downloads

15.

Trombose isolada de veia braquial em paciente com hiper-homocisteinemia
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Milhomem, Paula Sabrina Araujo

; Brandao, Marcelo Luiz

; Costa, Monica Meireles

; Sales, Werther Souza

; Santos, Juliano Ricardo Santana dos

; Riemma, Rodrigo Alves

; Alcantara, Viviane Queli Macedo de

Jornal Vascular Brasileiro

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sep 2013, Volume 12 N. 3 Pages 234 - 236

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/jvb.2013.036 5524 downloads

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