Aim To evaluate the influence of the parameters L* a* b* on the variation of the color of bovine tooth enamel submitted to artificial darkening, after simulated brushing, with whitening toothpastes containing blue covarine. Methods To undertake this study in vitro, 60 specimens (SP) were divided into 6 groups (n=10): control group (CGwater) and 5 test groups (GT1-Colgate Total 12, GT2-Oral-B 3D White Perfection, GT3-Colgate Luminous Instant White, GT4-CloseUp White Diamond Attraction, GT5-Sorriso Xtreme White). The specimens were darkened with coffee and submitted to simulated brushing for 6, 12, and 24 months. The alteration in the color was evaluated using CIELAB parameters and the ∆L, ∆a, ∆b and ∆E were calculated. The data was analyzed through generalized linear models using the R program and considering a level of significance of 5%. Results The parameters L*, a* and the ∆L, ∆a obtained better results in the test group than in the control group. There were no statistical differences between CG and the test groups for the evaluation of the b* parameter. In the evaluation of the ∆b, the GT3 differed statistically from the CG. In relation to the ∆E, all the group tests showed a variation in color statistically greater than that of the CG and the GT4 showed the greatest variation, not differing from the GT3 during the periods studied. Conclusion The mechanical and optical whitening agents positively influenced the values L*a* and b*, as well as in its variations and in the ∆E. It is important to emphasize, however, that to analyze tooth whitening it is necessary to evaluate their parameters together.

Resumo Introdução Formulações farmacêuticas pediátricas com baixo pH e alta acidez titulável usadas com frequência e por longos períodos de tempo têm potencial para produzir lesões erosivas nos dentes. Por outro lado, alta concentração de sacarose, uso noturno e falta de higiene bucal após a administração são fatores que podem contribuir para o potencial cariogênico dessas formulações. Objetivo Avaliar in vitro o potencial cariogênico e erosivo de medicamentos e suplementos vitamínicos e minerais líquidos de uso pediátrico. Material e método Medicamentos (n=41) e suplementos vitamínicos e minerais (n=12) líquidos infantis foram selecionados e analisados quanto às suas propriedades físico-químicas, pH, acidez total titulável (ATT) e concentração de sólidos solúveis totais (SST/°Brix). Bulas e rótulos foram analisados para a identificação do conteúdo em açúcares e acidulantes, além dos efeitos colaterais relacionados ao fluxo salivar. Resultado A análise do pH indicou que no grupo medicamentos houve maior variação nas médias observadas. Quanto à ATT em pH 5,5, os grupos medicamentos e suplementos apresentaram variação significativa entre as médias (p<0,05). Os resultados da ATT em pH 7,0 demonstraram que a maior média encontrada foi na classe dos anti-histamínicos e a menor na classe dos medicamentos que contém a associação de antitussígenos e anti-histamínicos. A análise de SST demonstrou que em todas as classes de medicamentos e nos suplementos a quantidade de SST variou significativamente (p<0,05). Conclusão Os medicamentos e suplementos vitamínicos e minerais líquidos apresentaram comportamentos diferentes dentro do mesmo grupo quanto às variáveis analisadas, apresentando potencial cariogênico e erosivo em sua maioria.

Abstract Introduction Pharmaceutical pediatric formulations with low in pH and high in total titratable acidicity used frequently and over long periods of time, have the potential to produce erosive lesions in teeth. On the other hand, high concentration of sucrose, the nocturnal use and the lack of hygiene after its administration, are some factors that can contribute to the cariogenic potential of these formulations. Objective To evaluate in vitro the cariogenic and erosive potential of medicines and liquid vitamins and mineral supplements for pediatric use. Material and method Medicines (n=41) and liquid vitamins and mineral supplements (n=12) childish were selected and analyzed for their physicochemical properties, pH, total titratable acidity (TTA) and total soluble solids concentration (TSS/°Brix). The package inserts and labels were analyzed to identify the composition regarding the content of sugars and acidulants, in addition to the side effects related to salivary flow. Result The pH analysis indicated that there was greater variation in the observed averages in the medication group. As for the TTA at pH 5.5, supplements and medicines groups showed significant variation between the means found (p<0.05). The TTA results at pH 7.0 showed that the highest mean found was in the class of antihistamines and the lowest in the class of drugs that contain the association of antitussives and antihistamines. The analyses TSS demonstrated that across all drug classes and supplements the amount of TSS varied significantly (p<0.05) in all classes of medicines and supplements. Conclusion Most medicines and pediatric liquid vitamin and mineral supplements demonstrated significantly different behaviors within the group itself regarding the variables analyzed that constitute risk factors for the development of dental caries and erosion.

Resumo Introdução O flúor é considerado um elemento chave no processo de remineralização do esmalte dentário. Objetivo Este estudo teve como objetivo avaliar a influência da solução tópica de fluoreto de sódio (NaF) na resistência ao cisalhamento da colagem de barquetes ortodônticos durante a formação de lesões de manchas brancas. Material e método Sessenta dentes bovinos foram divididos em três grupos (n=20). Grupo 1 (Controle) - Cisalhamento imediato; Grupo 2 - Cisalhamento após ciclagem de pH; Grupo 3 – Cisalhamento após ciclagem de pH e tratamento com solução de 0,4% de NaF (Ortho Gard, Colgate-Palmolive®). Os Grupos 2 e 3 sofreram ciclagem de pH com soluções de desmineralização e remineralização em pH de 4,3 e 7,0 respectivamente, com ciclos de desmineralização (6 horas) e remineralização (17 horas), durante 15 dias. Os corpos de prova foram submetidos ao teste de resistência de união ao cisalhamento e remanescente adesivo (IRA). Espécimes de cada grupo (n=3) foram analisados qualitativamente por microscopia eletrônica de varredura (MEV). O teste de Kruskal-Wallis foi utilizado para avaliar a resistência ao cisalhamento e o teste exato de Fisher para avaliação do IRA, adotando nível de significância de 5%. Resultado Os resultados não encontraram diferença significativa entre os três grupos quanto à força de cisalhamento (p=0,2679). Diferença significativa foi encontrada no IRA (p = 0,0199). A frequência de IRA 1 foi de 55% no grupo 1, 90% no grupo 2 e 80% no grupo 3. A análise em MEV mostrou diferença entre o esmalte e a área de colagem submetida ao cisalhamento. Grupo 2 apresentou alteração estrutural na superfície do esmalte adjacente à área de colagem, e o Grupo 3 apresentou esmalte com característica semelhante ao do Grupo 1 na área que foi submetida à ciclagem de pH e NaF. Conclusão Concluiu-se que não houve influência do flúor na resistência ao cisalhamento de braquetes. O uso de soluções fluoretadas, ainda que em baixa concentração, preveniu o aparecimento de áreas desmineralizadas e lesões de manchas brancas.

Abstract Introduction Fluoride is considered a key element in the remineralization process of tooth enamel. Objective To evaluate the influence of a topical solution of sodium fluoride (NaF) on the shear bond strength of orthodontic brackets and white spot lesions formation. Material and method Sixty bovine teeth were divided into three groups (n=20). Group 1 (Control): shear bond strength; Group 2: shear bond strength after pH cycling; Group 3: shear bond strength after pH cycling and treatment with 0.04% NaF solution. Groups 2 and 3 underwent pH cycling with demineralizing (6hs) and remineralizing (17hs) solutions at pH of 4.3 and 7.0 respectively for 15 days. The specimens were submitted to the shear bond strength and the Adhesive Remnant Index was verified (ARI). The specimens of each group (n=3) were qualitatively analyzed by means of Scanning Electron Microscopy (SEM). Kruskal-Wallis test assessed the shear bond strength and Fisher's exact test evaluated ARI, with significance level of 5%. Result There was no significant difference among the three groups in shear bond strength (p=0.2679). Significant difference was found in ARI (p=0.0199). The frequency of ARI 1 was 55% in group 1, 90% in group 2, and 80% in group 3. SEM showed difference between the enamel and bonding. Group 2 showed structural change of the enamel surface, adjacent to the bond area; and group 3 showed enamel with characteristics similar to those of group 1. Conclusion It was concluded that there was no NaF influence on the bracket shear bond strength and even in low concentrations it prevented the development of areas of demineralization of white spot lesions.

Resumo Introdução O Blue covarine é um pigmento que promove alterações ópticas nas superfícies dentárias proporcionando o seu branqueamento. Objetivo Avaliar in vitro o efeito de dentifrícios branqueadores contendo Blue covarine em resina composta nanoparticulada submetida a escurecimento artificial. Material e método 160 corpos de prova (CPs) de resina composta nanoparticulada FILTEK Z350XT foram divididos aleatoriamente em dois experimentos: Experimento I- 8 grupos (n=10) submetidos a escovação com escova elétrica por 1 mês; Experimento II- 8 grupos (n=10) submetidos a escovação simulada por 6, 12 e 24 meses. Os grupos foram distribuídos de acordo com a solução/dentifrício testado: GC (água destilada) e 7 grupos teste (GT1-Coltene Herjos, GT2- Colgate Total 12 Clean Mint, GT3- Colgate Luminous White Brilliant Mint, GT4- Oral B 3D White Perfection, GT5- Close Up White Now Glacier Fresh, GT6- Close Up White Attraction Diamond e GT7- Sorriso Xtreme White Evolution). Resultado No experimento I, houve maior ∆E no GT6 com relação ao GC, GT2, GT4 e GT5, que não diferiram entre si. No experimento II, após 24 meses de escovação houve maior ∆E nos grupos GT6 e GT7. Após 24 meses de escovação simulada não houve alteração da rugosidade nem perda de massa em nenhum grupo. Conclusão O efeito branqueador promovido pelos dentifrícios contendo o agente Blue covarine parece estar relacionado à associação deste agente com os abrasivos presentes nas formulações dos dentifrícios branqueadores.

Abstract Introduction Blue covarine is a pigment that promotes optical changes in dental surfaces, providing whitening. Objective To evaluate in vitro the effect of bleaching dentifrices containing Blue covarine in nanoparticulate composite resin subjected to artificial darkening. Material and method One hundred sixty (160) specimens (PBs) of FILTEK Z350XT nanoparticulate composite resin were randomly divided into two experiments: Experiment I - 8 groups (n=10) submitted to brushing with an electric toothbrush for 1 month; Experiment II - 8 groups (n=10) submitted to simulated brushing for 6, 12 and 24 months. Groups were distributed according to the solution/dentifrice tested: CG (distilled water) and 7 test groups (GT1- Coltene Herjos, GT2- Colgate Total 12 Clean Mint, GT3- Colgate Luminous White Brilliant Mint, GT4- Oral B 3D White Perfection, GT5- Close Up White Now Glacier Fresh, GT6- Close Up White Attraction Diamond and GT7- Sorriso Xtreme White Evolution). Result In Experiment I, there was greater ∆E in GT6 in relation to CG, GT2, GT4 and GT5, with no differences among them. In Experiment II, after 24 months of brushing, there was greater ∆E in groups GT6 and GT7. After 24 months of simulated brushing, there was no change in roughness or loss of mass in any group. Conclusion The whitening effect promoted by dentifrices containing the agent Blue covarine seems to be related to the association of this agent with the abrasives present in the formulations of whitening dentifrices.

Abstract Objective: To determine the relationship between tobacco and alcohol consumption and staging of head and neck cancer in patients treated at a referral hospital for cancer treatment. Material and Methods: This is a cross-sectional study based on medical records of patients with head and neck cancer treated between 2008 and 2015. The following variables were considered: gender, age, marital status, educational level, place of residence, profession, affected site, clinical staging of neoplasms, histopathological diagnosis, tobacco and alcohol consumption. Results: Of the 154 medical records analyzed, there was a predominance of male patients (72.7%), single (50%), with low education (88.1%), rural workers (38.3%), residents in the state countryside (70.2%) and aged 20-94 years. T3 and T4 size tumors prevailed. A significant correlation was found between alcohol use and tumor size (p=0.03) and presence of nodules (p<0.001), as well as between alcohol use and smoking with tumor size (p=0.04) and presence of nodules (p=0.019). No correlations were observed between tobacco use and injury staging. Conclusion: There was strong significance between tumor size and presence of nodules, both with the use of alcohol alone and with tobacco, thus suggesting the existence of important carcinogenic action of this substance.

Resumo Introdução O blue covarine é um agente branqueador que promove mudanças ópticas na superfície dos dentes, associado aos abrasivos dos dentifrícios, colaborando para o branqueamento dentário. Objetivo Determinar as alterações de cor, rugosidade e massa do esmalte bovino, após escovação simulada com dentifrícios branqueadores contendo blue covarine nos tempos 6, 12 e 24 meses. Material e método 80 corpos de prova (CP) foram divididos em 8 grupos (n = 10): grupo controle (GC-água) e 7 grupos teste (GT1-Colgate Total 12, GT2-Oral-B 3D White Perfection, GT3-Colgate Luminous Instant White, GT4-Close Up White Diamond Attraction, GT5-Close Up White-Glacier Fresh, GT6-Sorriso Xtreme White, GT7-Colgate Luminous White Advanced). Os CP foram escurecidos com café e submetidos à escovação simulada por 6, 12 e 24 meses. As avaliações de cor, rugosidade e massa foram realizadas após cada período de escovação. Resultado Nenhum dentifrício teste promoveu alterações significativas na rugosidade e massa dos CP, contudo, quando comparados ao GC todos promoveram branqueamento significativo. A comparação dos grupos teste não demonstrou diferença significativa na variação de cor entre GT1, GT2, GT3, GT5, GT6 e GT7 nos tempos estudados. O GT4 apresentou comportamento variável de acordo com o tempo, não diferindo estatisticamente de GT3 aos 6, 12 e 24 meses, de GT6 aos 6 e 12 meses e de GT7 aos 12 meses. Conclusão O efeito branqueador dos dentifrícios contendo blue covarine , após 2 anos de escovação, parece estar relacionado principalmente com a sua associação aos agentes branqueadores mecânicos, que promoveram o polimento das superfícies dentárias.

Abstract Introduction Blue covarine is a bleaching agent that produces optical changes on the surface of the teeth, associated with the abrasives of the dentifrice leading to tooth whitening. Objective To determine the changes in colour, roughness and mass of the bovine enamel, after simulated brushing with dentifrices - containing blue covariate bleaching - for 6, 12 and 24 months. Material and method 80 specimens were divided into 8 groups (n = 10): Control group (CG-water) and 7 test groups (TG1-Colgate Total 12, TG2-Oral-B 3D White Perfection, TG3 -Colgate Luminous Instant White, TG4-Close Up White Diamond Attraction, TG5-Close Up White Now-Glacier Fresh, TG6-Sorriso Xtreme White, TG7-Colgate Luminous White Advanced). The specimens were stained with coffee and subjected to simulated brushing for 6, 12 and 24 months. The colour, roughness and mass evaluations were performed after each brushing period. Result No dentifrice test produced significant alterations in the roughness and mass of the specimens, however, when compared to CG, all of themproduced significant whitening. The comparison of the test groups did not show a significant difference in the colour variation between TG1, TG2, TG3, TG5, TG6 and TG7 in the study. The TG4 presented a variable behavior according to time, not statistically differing from TG3 at 6, 12 and 24 months, neither from TG6 at 6 and 12 months nor from TG7 at 12 months. Conclusion The whitening effect of dentifrices containing blue covarine, after long periods of brushing, seems to be related mainly to association with mechanical bleaching agents, which, despite abrasives, did not damage the dental structure.

Objective: The purpose of this study was to evaluate the oral hygiene status in pediatric obese patients. Methods: A cross-sectional study was conducted from 2011 to 2012, which evaluated 180 Brazilian pediatric patients, 6-14 years old, girls and boys, recruited according to two Body Mass Index (BMI) categories: obese and non-obese (healthy weight). For the evaluation the oral hygiene status, the study used Oral Hygiene Index (OHI) and Gingival Bleeding Index (GBI). Results: According to the total sample, 5/60 obese (8.3%) and 57/120 non-obese (47.5%) had good OHI, while 23/60 obese (38.4%) and 3/120 non-obese (2.5%) were classified in a low level of OHI, with a significance between the groups (p < 0.001), even after sorting by age. According to the classification of GBI, 60/60 obese (100.0%) and 89/120 non-obese (74.2%) had GBI 1 (bleeding gingiva), and 0/60 obese and 31/120 non-obese (25.8%) were classified as GBI 0 (healthy gingiva), with a significance between the groups (p < 0.001), even after sorting by age. Conclusions: This study indicated that OHI and GBI were significantly higher in the obese children group.

Objetivo: El propósito de este estudio fue evaluar el estado de higiene oral en pacientes pediátrica con obesidad. Métodos: Un estudio transversal realizado en Brasil en el período 2011-2012, que evaluó 180 pacientes pediátricos de 6 a 14 años, niños y niñas, reclutados en el Índice de Masa Corporal (IMC) y separados en dos categorías: obesos y no obesos (peso saludable). Para evaluar el estado de la higiene oral, el estudio utilizó Indice de Higiene Oral (OHI) y índice de sangrado gingival (GBI). Resultados: De acuerdo con la muestra total, 5/60 obesos (8,3%) y 57/120 no obesos (47,5%) tuvieron buena OHI, mientras que 23/60 obesos (38,4%) y 3/120 no obesos (2,5%) fueron clasificado en un nivel bajo de OHI, con una significación entre los grupos (p < 0,001), incluso después de la clasificación por edades. De acuerdo con la clasificación de GBI, 60/60 obesos (100,0%) y 89/120 no obesos (74,2%) tenían GBI 1 (gingiva sangrante), y 0/60 obesos y 31/120 no obesos (25,8%) fueron clasificados como GBI 0 (gingiva sana), con una significación entre los grupos (p < 0,001), incluso después de la clasificación por edades. Conclusiones: Este estudio indicó que OHI y GBI fueron significativamente mayores en el grupo de niños obesos.

Objetivo: Avaliar, in vitro, a eficacia do gel do peroxido de hidrogenio a 35%, sem ativacao, nos tres tercos dentarios. Faces vestibulares de dentes pre-molares humanos foram escurecidos, seguindo-se de duas sessoes de clareamento com intervalos de 7 dias. A eficacia do clareamento foi determinada no terco cervical, terco medio e terco incisal pelo espectrofotometro Easyshade-Vita, com base no sistema CIELab. Os parametros L *, a *, b * determinados em cada um terco revelaram alta luminosidade e tendencia aos tons verde e amarelo; apos a pigmentacao, a luminosidade foi reduzida e os parametros a* e b* revelaram as tonalidades avermelhada e amarelada. 7 dias apos o primeiro clareamento houve uma melhora significativa dos parametros L * e a*. 7 dias apos o segundo clareamento, os tres parametros retornaram aos valores proximos aqueles iniciais, sendo que o parametro b * foi o principal fator responsavel pela eficacia de clareamento. Os valores referentes ao parametro DE indicaram haver percepcao visual. A remocao da pigmentacao foi satisfatoria apos os dois clareamentos, sendo que a falta de uniformidade entre os tercos apos a primeira sessao justificou a realizacao de dois procedimentos de clareamento. Em relacao a cada terco, o parametro DE mostrou percepcao visual, embora os valores de L*, a* e b* nao demonstraram diferencas estatisticamente significativas.

This study aimed to assess the efficacy of a 35% hydrogen peroxide - based gel without activation in vitro on three areas of the tooth surface. Vestibular faces of human premolar teeth were darkened, followed by two whitenings at 7-day intervals. The efficacy of whitening was determined in the cervical third, medium third and incisal third of the tooth surface with an Easyshade-Vita spectrophotometer based on the CIELab system. The L*, a*, b* parameters were determined for each third by the identification of high luminosity and hues tending to green and yellow; pigmentation luminosity was then reduced, and the parameters a* and b* became reddish and yellowish, respectively. Seven days after the first whitening, there were significant improvements in L* and a* values. Seven days after the second whitening, the three parameters returned to values close to the initial values; the b* parameter was most strongly correlated with whitening efficacy. DE values revealed a visually perceptible difference. There was a satisfactory removal of pigmentation after both whitenings, while the lack of uniformity among the tooth-surface thirds after the first session justified the performance of two whitening procedures. With regard to each third, DE indicated a visibly perceptible difference, although L*, a* and b* values showed no statistically significant differences.

OBJETIVOS: o objetivo deste estudo in vitro foi avaliar a resistência adesiva e o padrão de descolagem de diferentes sistemas de colagem de braquetes (Sistema Transbond XT / 3M-Unitek e Sistema Enlight / Ormco) cujos respectivos adesivos foram pré-misturados ao verniz de clorexidina (Cervitec / Ivoclar-Vivadent). METODOLOGIA: a amostra utilizada foi constituída por 60 pré-molares humanos, extraídos por indicações ortodônticas, incluídos em cilindros de PVC e divididos aleatoriamente em quatro grupos: grupo 1 - Sistema Transbond XT conforme prescrito pelo fabricante; grupo 2 - Sistema Transbond XT associado a verniz de clorexidina; grupo 3 - Sistema Enlight conforme prescrito pelo fabricante; grupo 4 - Sistema Enlight associado a verniz de clorexidina. A resistência adesiva foi avaliada pelo teste de cisalhamento na máquina de ensaios universal EMIC (0,5mm/min); o padrão de descolagem foi avaliado, através da lupa estereoscópica STEMI 2000-C / Zeiss (20x), pela observação do Índice de Adesivo Remanescente (IAR) na superfície do esmalte dentário, após a descolagem dos braquetes. RESULTADOS: não houve diferença estatisticamente significante (p < 0,05) entre os grupos experimentais (grupos 2 e 4) e os respectivos grupos controles (grupos 1 e 3). CONCLUSÕES: a resistência adesiva e o padrão de descolagem não foram alterados pela associação do verniz de clorexidina aos respectivos adesivos dos sistemas de colagem testados.

AIM: The objective of this in vitro study was to evaluate the bond strength and the debonding pattern of different bracket bonding systems (Transbond XT System / 3M-Unitek and Enlight System / Ormco) whose respective adhesives were pre-mixed with chlorhexidine varnish (Cervitec / Ivoclar-Vivadent). METHODS: The sample used consisted of sixty human pre-molars extracted for orthodontic purposes, included in PVC cylinder and randomly divided in four experimental groups: group 1 - Transbond XT System according to the manufacturer’s instructions; group 2 - Transbond XT System combined with chlorhexidine varnish; group 3 - Enlight System according to the manufacturer’s instructions; group 4 - Enlight System combined with chlorhexidine varnish. The bond strength evaluation was obtained through the shear bond strength test by EMIC universal test machine (0.5mm/minute); the debonding pattern evaluation was obtained by STEMI 2000-C/Zeiss (20x) stereoscopic microscope through observation of the adhesive remnant index (ARI) on the tooth’s enamel surface after bracket debonding. RESULTS: Between the experimental groups (groups 2 and 4) and the respective control groups (groups 1 and 3) there was no significant statistical difference (p < 0.05). CONCLUSIONS: The bond strength and the debonding pattern were not altered for association of the chlorhexidine varnish with respective adhesives of the tested bonding systems.