Abstract The restriction of nutrient intake by beef cows during pregnancy may influence the progeny postpartum growth potential, therefore, the objective of the present study was to evaluate the effects of nutritional restriction and adequate nutrition or overfeeding during the final third of gestation of the crossbred cows (Charolais x Nellore) kept in the Pampa biome, on the productive performance of the progeny up to 15 mo of age. Eighty-three (83) cows were divided into: control cows on natural pasture under nutritional restriction (RES); Supplementation to meet 100 % of requirements (REQ); Supplementation above requirements (HIGH). REQ and HIGH calves had higher body weight at birth compared to calves from RES cows (39.28, 39.13 vs 34.58 kg), without influences on postnatal performance. Females from REQ and HIGH cows presented better postnatal performance and consequently higher weight at 12 mo of age in compared to offspring RES cows (300.71 and 311.79 vs 259.47 kg). These female calves reached 60 % of early adult weight (358 and 345 vs 405 d) and had a higher percentage of breeding at twelve months of age (73.98 and 84.08 vs 34.08 %) than females from RES cows. Supplementing cows to meet 100% requirements, as well as overfeeding during the final third of gestation, improves offspring performance at twelve months of age, with males and females responding differently to maternal nutritional insults during this period.

Resumen La restricción de la ingesta de nutrientes por parte de las vacas de carne durante la gestación puede influir en el potencial de crecimiento posparto de la progenie, por lo que el objetivo del presente estudio fue evaluar los efectos de la restricción nutricional y de la nutrición adecuada o la sobrealimentación durante el último tercio de la gestación de las vacas cruzadas (Charolais x Nellore) criadas en el bioma pampeano, sobre el rendimiento productivo de la progenie hasta los 15 meses de edad. Ochenta y tres (83) vacas se dividieron en tres tipos de tratamiento: vacas de control en pastos naturales bajo restricción nutricional (RES); suplementación para satisfacer el 100 % de las necesidades (REQ); suplementación por encima de las necesidades (ALTO). Los terneros nacidos de vacas con tratamiento REQ y ALTO tuvieron un mayor peso corporal al nacimiento que los terneros de las vacas con tratamiento RES (39.28, 39.13 vs 34.58 kg), sin que esto haya influido en el rendimiento postnatal. Las hembras de las vacas con tratamiento REQ y ALTO presentaron un mejor rendimiento postnatal y, en consecuencia, un mayor peso a los 12 meses de edad en comparación con las crías de las vacas con tratamiento RES (300.71 y 311.79 frente a 259.47 kg). Estos terneros alcanzaron el 60 % del peso adulto temprano (358 y 345 vs 405 d) y tuvieron un mayor porcentaje de reproducción a los doce meses de edad (73.98 y 84.08 vs 34.08 %) que las hembras nacidas de las vacas con tratamiento RES. La suplementación de las vacas para satisfacer el 100 % de las necesidades, así como la sobrealimentación durante el último tercio de la gestación, mejora el rendimiento de las crías a los doce meses de edad, y los machos y las hembras responden de forma diferente a los insultos nutricionales de la madre durante este periodo.

O aneurisma e a trombose de veia porta são doenças raras do sistema porta, que comumente cursam sem sintomas. A grande maioria dos pacientes é diagnosticada com achados em exames de imagem. Os sintomas são atribuídos ao efeito de massa, no caso do aneurisma, e relativos à capacidade hepática de formar uma rede de circulação colateral, no caso da trombose. A escassa experiência nesses casos representa um dilema na abordagem desses pacientes e, portanto, a grande maioria dos autores opta por seguimento rigoroso e a intervenção é indicada apenas para os pacientes sintomáticos. Neste trabalho, relatamos um caso de aneurisma de veia porta e outro de trombose da veia porta, propondo o manejo e o acompanhamento desses pacientes.

Aneurysms and thromboses of the portal vein are rare pathologies of the portal system that commonly follow an asymptomatic course. The vast majority of cases are diagnosed as incidental findings during imaging studies. Symptoms of aneurysms are the result of mass effects, while thrombosis symptoms are a function of the liver's ability to form a collateral circulation network in the thrombosis. The scant experience with such cases poses a dilemma for patient management and so the vast majority of authors choose an expectant approach with rigorous patient surveillance and only intervene in symptomatic patients. We report one case of an aneurysm of the portal vein and one case of portal vein thrombosis and discuss management and observation of these patients.

Polímeros sintéticos biorreabsorvíveis podem ser utilizados sob a forma de membranas para sustentar e guiar o crescimento celular, através do processo de reparação tecidual. Este trabalho avaliou membranas de poli(ácido lático), PLLA, com adição de 10% de trietil-citrato usadas como curativos de feridas cutâneas agudas em ratos Wistar. Inicialmente uma ferida de 2cm² foi provocada na região dorsal de 24 animais. Estes foram divididos em 2 grupos: tratamento, nos quais as feridas foram recobertas pela membrana polimérica e controle, com feridas permanecendo cruentas. Os resultados obtidos em 1, 3, 7 e 15 dias mostraram uma resposta inflamatória mais satisfatória nas feridas protegidas pelas membranas, com reparação precoce e colágeno mais organizado quando comparadas com as áreas incialmente mantidas sem proteção. Além do que, as áreas protegidas pelas membranas não mostraram alterações inflamatórias irritativas que pudessem ser imputadas ao uso da membrana polimérica. Diante disso, conclui-se que a membrana de PLLA/Trietil-citrato protegeu efetivamente as feridas, permitindo o processo de reparação e mostrando-se promissora como curativo cutâneo.

Bioresorbable polymers can be applied as membranes to sustain and guide cell growth through the regeneration process. This study evaluated poly(acid lactide), PLLA, membranes with addition of 10% triethyl citrate as skin wound healing in Wistar rats. Initially a 2cm² skin wound was exercised of the back of 24 animals. The animals were divided into two groups: treated, whose the polymer membrane was implanted, and control, in which the wound was kept exposed. The results obtained after 1, 3, 7 and 15 days showed an inflammatory response more satisfactory in the implanted wounds, with early repair and collagen more organized when compared to exposed wounds. In addition to, the protected areas showed no irritant inflammatory response which could be attributed to the membrane. Thus, we conclude that the PLLA/Triethyl citrate membrane has effectively protected the wounds, allowing the repair and presenting itself as a promising skin dressing.