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Resumo A atividade antioxidante do mel de Tetragonisca angustula (TAH) e seu extrato etanólico (TAEE) foram investigados. Os níveis totais de fenólicos (TPC) e flavonóides (TFC) também foram avaliados. Os resultados para TPC foram 19,91 ± 0,38 e 29,37 ± 1,82 mg GAE g-1 e para TFC 0,20 ± 0,02 e 0,14 ± 0,01 mg QE g-1 de TAH e TAEE, respectivamente. As atividades antioxidantes foram 73,29 ± 0,49% e 93,36 ± 0,27% no ensaio DPPH● e 71,73 ± 4,07% e 97,86 ± 0,35% no ABTS●+ para TAH e TAEE, respectivamente. A atividade redutora total foi determinada pelo método de poder redutor (PR) e íon ferrico (Fe III) e os resultados variaram em PR de 151,7 ± 25,7 e 230,7 ± 25,2 mg GAE L-1, para TAH e TAEE respectivamente e para (Fe III) em EC50 0,284 em TAEE e 0,687 em TAH. A análise química por HPLC-DAD do extrato etanólico (TAEE) revelou a presença de ácido ferúlico como componente majoritário no extrato. A análise de RMN 1H confirmou esta estrutura e mostrou a presença de glicose, ácido cítrico, ácido succínico, prolina e derivados de hidrocarbonetos no TAEE. Além disso, a origem botânica também foi investigada e apresentou característica multifloral, tendo encontrado 19 tipos polínicos com predomínio botânico da família Anacardiaceae, sendo o pólen Tapirira predominante (42,6%) e o Schinus secundário (25,7%). Os resultados mostraram que o mel de T. angustula é uma interessante fonte de compostos fenólicos antioxidantes devido à sua origem floral e pode atuar como protetor da saúde humana quando consumido.

Abstract The antioxidant activity of Tetragonisca angustula honey (TAH) and its ethanolic extract (TAEE) were investigated. The total levels of phenolic (TPC) and flavonoids (TFC) were also evaluated. The results for TPC were 19.91 ± 0.38 and 29.37 ± 1.82 mg GAE g-1 and for TFC 0.20 ± 0.02 and 0.14 ± 0.01 mg QE g-1 of TAH and TAEE, respectively. Antioxidant activities were 73.29 ± 0.49% and 93.36 ± 0.27% in the DPPH● assay and 71.73 ± 4.07% and 97.86 ± 0.35% in ABTS●+ for TAH and TAEE, respectively. The total reducing activity was determined by the method of reducing power (PR) and iron ion (Fe III) and the results varied in PR from 151.7 ± 25.7 and 230.7 ± 25.2 mg GAE L-1, for TAH and TAEE respectively and for (Fe III) in EC50 0.284 in TAEE and 0.687 in TAH. Chemical analysis by HPLC-DAD of the ethanolic extract (TAEE) revealed the presence of ferulic acid as majority phenolic component in the extract. The 1H NMR analysis confirmed this structure and showed the also presence of glucose, citric acid, succinic acid, proline and hydrocarbon derivatives. In addition, the botanical origin was also investigated and showed a multifloral characteristic, having found 19 pollen types with a botanical predominance of the Anacardiaceae family, with Tapirira pollen occurring as predominant (42.6%) and Schinus as secondary (25.7%). The results showed that T. angustula honey is an interesting source of antioxidant phenolic compounds due to its floral origin and can act as a protector of human health when consumed.

https://doi.org/10.1590/1519-6984.253599

Translucency parameters of different CAD/CAM ceramics for monolithic restorations
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Carneiro, C. M. A.

; Paulart, M. M.

; Correr, G. M.

; Cunha, L. F. da

; Diógenes, A. N.

; Gonzaga, C. C.

Cerâmica

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jul 2023, Volume 69 N. 391 Pages 248 - 253

Abstract: En | Text: En | PDF: En

Abstract The translucency of dental ceramics [feldspathic ceramic (FC), lithium disilicate glass-ceramic (LD), zirconia-reinforced lithium silicate glass-ceramic (LS), and translucent zirconia (TZ)], in two thicknesses (1 and 2 mm), using different parameters was assessed. Translucency parameters ( TP ab *, TP00), contrast ratio (CR), light transmittance at 468 nm (T%), and light attenuation were determined. Data were analyzed by ANOVA, Tukey’s test, and Pearson correlations (α=0.05). CR ranged from 0.64 (LS-1 mm) to 0.96 (TZ-2 mm). TP ab * ranged from 3.7 (TZ-2 mm) to 32.2 (LS-1 mm). TP00 ranged from 3.0 (TZ-2 mm) to 26.4 (LS-1 mm). T% ranged from 14.9 (TZ-2 mm) to 75.2 (FC-1 mm). Light attenuation varied from 54% (LS-1 mm) to 84% (TZ-2 mm). There were significant strong negative correlations between CR and TP ab * (R=-0.997), CR and TP00 (R=-0.991), TP ab * and light attenuation (R=-0.888), and TP00 and light attenuation (R=-0.867). LS showed the highest translucency, whereas TZ showed the lowest translucency. When thickness increased, CR and light attenuation also increased, while TP and transmittance decreased.

https://doi.org/10.1590/0366-69132023693913476

Residência Médica e Reforma Psiquiátrica brasileira: convergências e conflitos na formação para o cuidado em saúde mental
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Carneiro, Pedro Carlos

; Ayres, José Ricardo de C. M.

Physis: Revista de Saúde Coletiva

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2023, Volume 33 elocation e33047

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O estudo tem por objetivo identificar em que medida e de que forma os princípios, diretrizes e métodos propostos pela Reforma Psiquiátrica Brasileira (RPB) estão presentes na formação dos psiquiatras em programas de Residência Médica. Trata-se de estudo qualitativo que investiga conteúdos e experiências promovidos durante a formação em programas de Residência Médica de Psiquiatria no Brasil. Foram entrevistados 16 sujeitos em quatro instituições públicas de formação, sendo dois programas centrados em hospitais-escola e outros dois em modelos integrados a serviços da Rede de Atenção Psicossocial. Os resultados do estudo permitem sustentar que, apesar de todos os programas remeterem a princípios da RPB em seus conteúdos teóricos, as oportunidades de prática dos modelos integrados dialogam mais diretamente com a experiência da RPB. Entre outros resultados relevantes, destacam-se: preocupação com o cuidado integral, não centrado apenas nos diagnósticos e sintomas, mas na singularidade e no andar a vida dos sujeitos; crítica à medicalização, seja na forma do uso abusivo de medicação, seja como interferência em demandas não especificamente médicas; importância de experiências interdisciplinares em equipes multiprofissionais e uma proposta da superação de uma cultura manicomial que vai além da institucionalidade dos serviços, mas que opera nos processos cotidianos de normalização social.

Abstract The study aims to identify to what extent and how the principles, guidelines and methods proposed by the Brazilian Psychiatric Reform (BPR) are present in the training of psychiatrists in medical residency programs. This is a qualitative study that investigates contents and experiences promoted during training in psychiatric medical residency programs in Brazil. A total of 16 subjects were interviewed in four public training institutions, two programs centered on school hospitals and two in models integrated with psychosocial care network services. The results of the study allow us to argue that, although all programs refer to BPR principles in their theoretical contents, the services integrated programs seems to promote a closer dialogue with the BPR experience. Among other relevant results, the following stand out: concern with comprehensive care, not focused only on diagnoses and symptoms, but on the singularity and ways of life of the subjects; criticism of medicalization, either in the form of abuse of medication, or as interference in non-specifically medical demands; relevance of interdisciplinary experiences in multidisciplinary teams and the aim to overcome a manicomial culture that goes beyond the institutionality of services, but that operates in the daily processes of social normalization.

https://doi.org/10.1590/s0103-7331202333047

Evaluation of pediatric diabetes mellitus after SARS-CoV-2 infection: A long-term prospective case series
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Fink, Thais T.

; Canton, Ana P.M.

; Pereira, Maria Fernanda B.

; Bain, Vera

; Matsuo, Olívia

; Astley, Camilla

; Marques, Heloisa H.S.

; Correa-Silva, Simone

; Montenegro, Marilia M.

; Palmeira, Patricia

; Garanito, Marlene P.

; Duarte, Alberto J.S.

; Carneiro-Sampaio, Magda

; Latronico, Ana C.

; Silva, Clovis A.

Clinics

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2023, Volume 78 elocation 100299

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.clinsp.2023.100299

Emotional, hyperactivity and inattention problems in adolescents with immunocompromising chronic diseases during the COVID-19 pandemic
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Campos, Reinan T.

; Lindoso, Livia

; Sousa, Renan A. de

; Helito, Alberto C.

; Ihara, Bianca P.

; Strabelli, Claudia A.A.

; Paradelas, Levi M.V.

; Carneiro, Beatriz O.L.

; Cardoso, Maria Paula R.

; Souza, Jean Paulo V. de

; Freire, Marianna R. de M.

; Astley, Camilla

; Laurentino, Moisés F.

; Buscatti, Izabel M.

; Kozu, Katia

; Aikawa, Nadia E.

; Sallum, Adriana M.E.

; Ferreira, Juliana CO.

; Simon, Juliana R.

; Viana, Vivianne S.L.

; Queiroz, Ligia B.

; Gualano, Bruno

; Roschel, Hamilton

; Pereira, Rosa Maria R.

; Toma, Ricardo K.

; Watanabe, Andréia

; Grangeiro, Patricia M.

; Casella, Caio B.

; Farhat, Sylvia C.

; Polanczyk, Guilherme V.

; Campos, Lucia Maria A.

; Silva, Clovis A.

Clinics

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2023, Volume 78 elocation 100167

Abstract: En | Text: En | PDF: En

Abstract Objective: To assess factors associated with emotional changes and Hyperactivity/Inattention (HI) motivated by COVID-19 quarantine in adolescents with immunocompromising diseases. Methods: A cross-sectional study included 343 adolescents with immunocompromising diseases and 108 healthy adolescents. Online questionnaires were answered including socio-demographic data and self-rated healthcare routine during COVID-19 quarantine and validated surveys: Strengths and Difficulties Questionnaire (SDQ), Pittsburgh Sleep Quality Index (PSQI), Pediatric Quality of Life Inventory 4.0 (PedsQL4.0). Results: The frequencies of abnormal emotional SDQ scores from adolescents with chronic diseases were similar to those of healthy subjects (110/343 [32%] vs. 38/108 [35%], p = 0.548), as well as abnormal hyperactivity/inattention SDQ scores (79/343 [23%] vs. 29/108 [27%], p = 0.417). Logistic regression analysis of independent variables associated with abnormal emotional scores from adolescents with chronic diseases showed: female sex (Odds Ratio [OR = 3.76]; 95% Confidence Interval (95% CI) 2.00–7.05; p < 0.001), poor sleep quality (OR = 2.05; 95% CI 1.08–3.88; p = 0.028) and intrafamilial violence during pandemic (OR = 2.17; 95% CI 1.12–4.19; p = 0.021) as independently associated with abnormal emotional scores, whereas total PedsQL score was inversely associated with abnormal emotional scores (OR = 0.95; 95% CI 0.93–0.96; p < 0.0001). Logistic regression analysis associated with abnormal HI scores from patients evidenced that total PedsQL score (OR = 0.97; 95% CI 0.95–0.99; p = 0.010], changes in medical appointments during the pandemic (OR = 0.39; 95% CI 0.19–0.79; p = 0.021), and reliable COVID-19 information (OR = 0.35; 95% CI 0.16–0.77; p = 0.026) remained inversely associated with abnormal HI scores. Conclusion: The present study showed emotional and HI disturbances in adolescents with chronic immunosuppressive diseases during the COVID-19 pandemic. It reinforces the need to promptly implement a longitudinal program to protect the mental health of adolescents with and without chronic illnesses during future pandemics.

https://doi.org/10.1016/j.clinsp.2023.100167

Digiwork: Reflections on the scenario of work mediated by digital platforms in Brazil
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Carneiro, Laila L.

; Moscon, Daniela C. B.

; Dias, Liz M. M.

; Oliveira, Stéfanie M. D.

; Alves, Haiana M. C.

RAM. Revista de Administração Mackenzie

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2023, Volume 24 N. 2 elocation eRAMR230060

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: This article analyzes the Brazilian scenario of work mediated by digital platforms (digiwork). Originality/value: Digiwork represents an alternative work arrangement to the traditional long-term employment model, with the highest growth rate in recent years. Details of this scenario are still unclear regarding the quantity and diversity of the offered products and services and the number of individuals involved. This article presents information and reflections that contribute to understanding these data in Brazil. Design/methodology/approach: This is an analytical-exploratory study. Scientific articles were used to discuss technological, political, and socioeconomic influences that supported the emergence of digiwork and its effects on the labor market and the workforce. In order to support this discussion, a documental analysis of websites and mobile application software was carried out, allowing for a qualitative-quantitative mapping of Brazil’s current digital intermediation platforms. Findings: More than 100 companies operating in the country were identified as offering 11 types of services in this business, indicating a growing trend. A diversification movement was also observed, absorbing professionals with different kinds of training and schooling levels. Such growth is in line with the political-economic trend of encouraging the loosening of labor relations, which individualizes and informalizes the bonds, emphasizing the need for debate on the regulation of this work arrangement and more research to investigate its repercussions on the worker’s health, also considering the heterogeneity present in this new class.

RESUMO Objetivo: Este artigo analisa o cenário brasileiro do trabalho mediado por plataformas digitais (digitrab). Originalidade/valor: O digitrab representa o arranjo laboral alternativo ao modelo de emprego tradicional de longo termo que mais tem crescido nos últimos anos. Entretanto, não conhecemos com clareza esse cenário, nem em termos de quantidade nem de diversidade de produtos e serviços ofertados, muito menos quanto ao volume de indivíduos envolvidos. O presente artigo apresenta informações e reflexões que colaboram para a compreensão desses dados no Brasil. Design/metodologia/abordagem: Trata-se de um estudo analítico-exploratório. Artigos científicos foram utilizados para discutir as influências tecnológicas, políticas e socioeconômicas que favoreceram a emergência do digitrab e seus efeitos no mundo do trabalho e nos trabalhadores. Para sustentar tal discussão, foi feita uma análise documental de sites e aplicativos móveis (apps) que permitiu um mapeamento quali-quantitativo acerca das plataformas digitais de intermediação ativas no Brasil atualmente. Resultados: Foram identificadas mais de 100 empresas atuantes no país que oferecem 11 tipos de serviços nessa modalidade de negócio, com indicação de tendência de crescimento. Observou-se também um movimento de diversificação, absorvendo profissionais de diferentes tipos de formação e níveis educacionais. Tal crescimento se alinha à tendência político-econômica de incentivo ao afrouxamento das relações de trabalho, que individualiza e informaliza os vínculos, enfatizando a neces-sidade de debate sobre a regulamentação desse arranjo de trabalho e de mais pesquisas que se debrucem a investigar suas repercussões sobre a saúde do trabalhador, considerando, ainda, a heterogeneidade presente nessa nova classe.

https://doi.org/10.1590/1678-6971/eramr230060.en

Epidemiology of mastitis and interactions of environmental factors on udder health in the compost barn system
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Fonseca, M.

; Mendonça, L.C.

; Souza, G.N.

; Cesar, D.E.

; Carneiro, J.C.

; Brito, E.C.

; Mendonça, J.F.

; Brito, M.A.V. Paiva e

; Guimarães, A.S.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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2023, Volume 75 N. 1 Pages 14 - 26

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT This study aimed to describe the epidemiological indexes of mastitis, milk quality and udder hygiene in the Compost Barn system, as well as to search for associations between isolated pathogens from milk with compost characteristics. Three dairy herds participated in the study, and the samples were collected during different periods on each farm. Individual milk samples were collected in duplicate for SCC analysis and microbiological culture. Environmental pathogens caused most cases of clinical mastitis on farm 2, and contagious pathogens caused the most cases on farm 1. Bed moisture was not associated with the incidence of environmental pathogens. Most of the animals remained in good udder hygiene during the study. Poor udder hygiene contributed to the increased incidence of environmental pathogens in one of the farms. A higher number of animals with a hygiene score of ≥ 2 were observed during the warmer and rainfall periods. There was no association between hygiene scores and somatic cell counts. The results suggest that pathogens isolated from milk in animals confined in Compost Barn under tropical climate are like other confinement systems adopted elsewhere. The year period influenced the udder hygiene score, reinforcing the importance of bed management throughout the year.

RESUMO O objetivo deste estudo foi descrever os índices epidemiológicos da mastite, da qualidade do leite e da higiene do úbere em animais confinados no sistema Compost Barn, bem como buscar associações entre patógenos isolados do leite e características do composto. Três rebanhos leiteiros participaram do estudo e as amostras foram coletadas em diferentes períodos em cada fazenda. Amostras individuais de leite foram coletadas em duplicata para análise de CCS e cultura microbiológica. Patógenos ambientais causaram a maioria dos casos de mastite clínica na fazenda 2, e na fazenda 1 a maioria dos casos foi em decorrência de patógenos contagiosos. Amostras de material da cama foram coletadas em duas fazendas para análise da densidade bacteriana e da umidade. A umidade da cama permaneceu dentro da faixa de controle durante o estudo e não foi associada à incidência de patógenos ambientais. A maioria dos animais permaneceu com boa higiene de úbere durante o estudo. A falta de higiene do úbere contribuiu para o aumento da incidência de patógenos ambientais em uma das fazendas. Durante o período mais quente e mais chuvoso, um número maior de animais com escore de sujidade ≥ 2 foi observado em todos os rebanhos. Não houve associação entre escore de sujidade e contagem de células somáticas em qualquer uma das três fazendas. Os resultados indicam que o perfil de patógenos isolados do leite em animais confinados em Compost Barn sob clima tropical é semelhante a outros sistemas de confinamento adotados em outros lugares. O período do ano influenciou o escore de higiene do úbere, o que reforça a importância do manejo da cama ao longo do ano.

https://doi.org/10.1590/1678-4162-12798

In vitro manipulation of the bacterial community to improve the performance of bioflocs in aquaculture systems
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SILVA, JÉSSICA L.S. DA

; CARNEIRO, ANA P.C.

; BRITO, ANNA L.C.

; OLIVEIRA, ANA V.S.

; VIEIRA, JHONES L.

; SOARES, RAQUEL C.

; FREITAS, ROBÉRIO M. DE

; SOUSA, OSCARINA V. DE

Anais da Academia Brasileira de Ciências

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2023, Volume 95 N. 1 elocation e20220311

Abstract: En | Text: En | PDF: En

Abstract Although biofloc technology is already recognized as advantageous and practical for aquaculture for the effects of maintaining water quality and improving the health status and resistance of cultivated animals against pathogens, little is known about the way of action involved. This study aimed to evaluate the performance of bacterial groups as inducers in the formation of flocs compared to a system with spontaneous formation. Therefore, three microsystems were built in 3L tanks with constant aeration to induce the biofloc aggregation with addition of bacterial consortiuns with differentiated functions. It was used a control, without addition of bacterial consortium; B1 with addition of probiotic bacteria consortium; and B2, with adding nitrifying bacteria consortium. During the experimental period were evaluated physicochemical variables and quantifications of bacterial cultivable groups: Heterotrophic Bacteria and Vibrio. Also was the microscopic characterization of the flakes and tests of antimicrobial activity against pathogenic bacteria. Systems B1 and B2 showed promising results in relation to control (spontaneous bioflocs), showing more homogeneous flake formation, antimicrobial activity against the tested pathogens and greater biological diversity in the systems. The bacteria used in these tests were able to optimize the formation of microbial aggregates, showing potential for application in cultivation systems, in order to obtain improvements in productivity.

https://doi.org/10.1590/0001-3765202320220311

Reaction of common bean genotypes to plant parasitic nematodes
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Dias, Waldir Pereira

; Wendland, Adriane

; Souza Carneiro, Geraldo Estevam de

; Oliveira Filho, Flavio Gonçalves de

; Lopes, Ivani de Oliveira Negrão

Pesquisa Agropecuária Tropical

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2023, Volume 53 elocation e74717

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Among the efficient strategies to manage plant parasitic nematodes, the use of resistant cultivars stands out for being frequently the easiest and least expensive approach that can be adopted by farmers. However, for the common bean, in Brazil, few sources of resistance have been identified so far. This study aimed to assess the reaction of 81 common bean genotypes to the most abundant and harmful plant parasitic nematode species in Brazilian crop fields. Genotypes resistant to all tested nematodes were observed: 7 to Heterodera glycines, 2 to Pratylenchus brachyurus, 15 to Meloidogyne incognita and 8 to M. javanica.

RESUMO Entre as estratégias eficientes de manejo de fitonematoides, o uso de cultivares resistentes se destaca por ser frequentemente a abordagem mais fácil e menos onerosa que pode ser adotada pelos agricultores. Entretanto, no caso do feijoeiro comum, no Brasil, poucas fontes de resistência foram identificadas até o momento. Objetivou-se avaliar a reação de 81 genótipos de feijão comum às espécies de fitonematoides mais abundantes e nocivas nas lavouras brasileiras. Foram observados genótipos resistentes a todos os nematoides testados: 7 a Heterodera glycines, 2 a Pratylenchus brachyurus, 15 a Meloidogyne incognita e 8 a M. javanica.

https://doi.org/10.1590/1983-40632023v5374717

10.

Fast and Green Hematite (α-Fe2O3) and Akaganeite (β-FeOOH) Synthesis Using a Microwave-Assisted Hydrothermal Process with Single Precursor and No Stabilizing Agent
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Diniz, Paulo Afonso F.

; Cavalcante, Kiany Sirley B.

; Souza, Josiane Carneiro

; Marques, Gleison N.

; Santos, Fernanda Hellen de S.

; Cutrim, Fiama M.

; Henriques, Raelma B.

; Mendonça, Leonardo T. B.

; Nascimento, Ulisses M.

Materials Research

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2023, Volume 26 elocation e20230016

Abstract: En | Text: En | PDF: En

In this work, iron chloride (FeCl3.6H2O), a single reagent, was used to create the phases of hematite (α-Fe2O3) and akaganeite (β-FeOOH) without the need of organic solvents using the microwave-assisted hydrothermal technique (HM). X-ray diffraction demonstrated the efficacy of the HM technique in the generation of crystalline phases of α-Fe2O3 at 180oC and β-FeOOH at 120oC. The development of pseudo-cunic and stick-like particles was a result of changes in experimental variables, which also had a substantial impact on the materials structural characteristics. The nitrogen (N2) adsorption/desorption isotherms of the samples containing akaganeite and hematite phase resembled those of mesoporous materials. Hematite has a surface area of 25.44 m2 g-1, while akaganeite has a surface area of 110.60 m2 g-1, according to the calculation. Thermodifferential and thermogravimetric techniques were used to assess thermal degradation. The use of microwave hydrothermal synthesis was promoted as being quick, easy, affordable, and safe for the environment.

https://doi.org/10.1590/1980-5373-mr-2023-0016

11.

Major discrepancy between clinical diagnosis of death and anatomopathological findings in adolescents with chronic diseases during 18-years
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Ribeiro, Maira P.

; Duarte Neto, Amaro N.

; Dolhnikoff, Marisa

; Lindoso, Livia

; Lourenco, Benito

; Marques, Heloisa H.

; Pereira, Maria F.B.

; Cristofani, Lilian M.

; Odone Filho, Vicente

; Campos, Lucia M.A.

; Sallum, Adriana M.E.

; Carneiro-Sampaio, Magda

; Delgado, Artur F.

; Carvalho, Werther B.

; Mauad, Thais

; Silva, Clovis A.

Clinics

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2023, Volume 78 elocation 100184

Abstract: En | Text: En | PDF: En

Abstract Objectives: To evaluate the inconsistency between clinical diagnosis of death and autopsy findings in adolescents with chronic diseases. Methods: A cross-sectional study including a sample of adolescents’ autopsies who died in a pediatric and adolescent tertiary hospital over 18 consecutive years. During this period, there were n = 2912 deaths, and n = 581/2912(20%) occurred in adolescents. Of these, n = 85/581(15%) underwent autopsies and were analyzed. Further results were divided into two groups: Goldman classes I or II (high disagreement between main clinical diagnosis of death and anatomopathological findings, n = 26) and Goldman classes III, IV or V (low or no disagreement between these two parameters, n = 59). Results: Median age at death (13.5 [10‒19] vs. 13 [10‒19] years, p = 0.495) and disease duration (22 [0‒164] vs. 20 [0‒200] months, p = 0.931), and frequencies for males (58% vs. 44%, p = 0.247) were similar between class I/II vs. class III/IV/V. The frequency of pneumonia (73% vs. 48%, p = 0.029), pulmonary abscess (12% vs. 0%, p = 0.026), as well as isolation of yeast (27% vs. 5%, p = 0.008), and virus (15% vs. 2%, p = 0.029) identified in the autopsy, were significantly higher in adolescents with Goldman class I/II compared to those with Goldman class III/IV/V. In contrast, cerebral edema was significantly lower in adolescents of the first group (4% vs. 25%, p = 0.018). Conclusion: This study showed that 30% of the adolescents with chronic diseases had major discrepancies between clinical diagnosis of death and autopsy findings. Pneumonia, pulmonary abscess, as well as isolation of yeast and virus were more frequently identified at autopsy findings in the groups with major discrepancies.

https://doi.org/10.1016/j.clinsp.2023.100184

12.

Asymptotic Behaviour of a Viscoelastic Transmission Problem with a Tip Load
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RIVERA, J. E. M.

; CARNEIRO, M. S.

; FERNANDES, M. A. A.

Trends in Computational and Applied Mathematics

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2023, Volume 24 N. 2 Pages 357 - 375

Abstract: En | Text: En | PDF: En

ABSTRACT We consider a transmission problem for a string composed by two components: one of them is a viscoelastic material (with viscoelasticity of memory type), and the other is an elastic material (without dissipation effective over this component). Additionally, we consider that in one end is attached a tip load. The main result is that the model is exponentially stable if and only if the memory effect is effective over the string. When there is no memory effect, then there is a lack of exponential stability, but the tip load produces a polynomial rate of decay. That is, the tip load is not strong enough to stabilize exponentially the system, but produces a polynomial rate of decay.

https://doi.org/10.5540/tcam.2023.024.02.00357

13.

A model for preservation of thymocyte-depleted thymus
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Dias, A.S.

; Damaceno-Rodrigues, N.R.

; Gimenez, T.M.

; Oliveira, P.M.

; Zerbini, M.C.

; Carneiro-Sampaio, M.

; Odone Filho, V.

; Jatene, M.B.

; Vasconcelos, D.M.

; Rocha, V.

; Novak, E.M.

Brazilian Journal of Medical and Biological Research

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2023, Volume 56 elocation e12647

Abstract: En | Text: En | PDF: En

DiGeorge syndrome is a disorder caused by a microdeletion on the long arm of chromosome 22. Approximately 1% of patients diagnosed with DiGeorge syndrome may have an absence of a functional thymus, which characterizes the complete form of the syndrome. These patients require urgent treatment to reconstitute T cell immunity. Thymus transplantation is a promising investigational procedure for reconstitution of thymic function in infants with congenital athymia. Here, we demonstrate a possible optimization of the preparation of thymus slices for transplantation through prior depletion of thymocytes and leukocyte cell lineages followed by cryopreservation with cryoprotective media (5% dextran FP 40, 5% Me2SO, and 5% FBS) while preserving tissue architecture. Thymus fragments were stored in liquid nitrogen at -196°C for 30 days or one year. The tissue architecture of the fragments was preserved, including the distinction between medullary thymic epithelial cells (TECs), cortical TECs, and Hassall bodies. Moreover, depleted thymus fragments cryopreserved for one year were recolonized by intrathymic injections of 3×106 thymocytes per mL, demonstrating the capability of these fragments to support T cell development. Thus, this technique opens up the possibility of freezing and storing large volumes of thymus tissue for immediate transplantation into patients with DiGeorge syndrome or atypical (Omenn-like) phenotype.

https://doi.org/10.1590/1414-431x2023e12647

14.

Differential composition of reserves and oil of Moringa oleifera seeds cultivated in states of Northeast Brazil
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Chaves, Josyelem Tiburtino Leite

; Silva, Toshik Iarley da

; Bicalho, Elisa Monteze

; Paula, Ana Cardoso Clemente Filha Ferreira de

; Souto, Patrícia Carneiro

; Souto, Jacob Silva

Ciência e Agrotecnologia

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2023, Volume 47 elocation e007823

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Moringa oleifera (Lam.) is an oilseed rich in unsaturated fatty acids. The seed reserve composition can change according to environmental conditions of precipitation and temperature. Thus, this work aimed to characterize the M. oleifera seed and its vegetable oil from plants cultivated in different states of Northeast Brazil. Seeds and soil samples were collected in Bahia (BA), Ceará (CE), Paraíba (PB), and Rio Grande do Norte (RN). Regarding climate variables, RN and BA had the lowest (395 mm) and highest (880 mm) precipitation during the collection year, respectively. The size and mass of the seeds and almonds, and the characterization of the flour and the oil of the ‘moringa’ seeds were measured. The largest seeds and almonds were collected in BA and the smallest in RN. The highest protein and moisture contents were obtained in the seeds from CE. The seeds from RN had the highest oil content, unsaturated fatty acids, ashes, acidity, and saponification levels. Thus, RN presents the smallest seeds of M. oleifera with higher content of mineral salts (ashes), oil, and monounsaturated fatty acids.

RESUMO Moringa oleifera (Lam.) é uma oleaginosa rica em ácidos graxos insaturados. A composição de reserva da semente pode mudar de acordo com as condições ambientais de precipitação e temperatura. Assim, objetivou-se com este trabalho caracterizar sementes e o óleo vegetal de M. oleifera cultivado em diferentes estados do Nordeste do Brasil. As sementes e amostras de solo foram coletadas na Bahia (BA), Ceará (CE), Paraíba (PB) e Rio Grande do Norte (RN). Em relação às variáveis climáticas, RN e BA apresentaram a menor (395 mm) e a maior (880 mm) precipitação durante o ano de coleta. As sementes e amêndoas foram medidas e realizada a caracterização da farinha e do óleo de moringa. As maiores sementes e amêndoas foram coletadas na BA e as menores no RN. O maior teor de proteínas e umidade foram obtidos nas sementes do CE. As sementes do RN apresentaram o maior teor de óleo, níveis de acidez e saponificação e a maior quantidade de ácidos graxos insaturados. Assim, o RN possui as menores sementes de M. oleifera com maior teor de sais minerais, óleo e ácidos graxos monoinsaturados.

https://doi.org/10.1590/1413-7054202347007823

15.

Assessment of the Health Risk of Indigenous People by the Consumption of Fish with Hg and As in Villages Located Close to Mining
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Silva, Luciano V. D. da

; Pereira, Simone F. P.

; Carneiro, Cristiane C.

; Silva, Thiago M. e

; Rocha, Ronaldo M.

; Costa, Hemilton C. da

; Silva, Cleber S. e

; Souza, Alan M. F. de

; Silva, Maria L. S. da

Journal of the Brazilian Chemical Society

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2023, Volume 34 N. 12 Pages 1796 - 1809

Abstract: En | Text: En | PDF: En

The Amazon suffers from the occurrence of mining along its hydrographic routes, which releases toxic substances into the aquatic environment. The objective of this study was to evaluate the risk of contamination by As and Hg that indigenous peoples are exposed to through the consumption of fish in an area impacted by mining activity in the basin of the Curuá and Baú Rivers, Altamira-PA. In total, 55 fish specimens and 30 surface water samples were collected. The decomposition of the fish samples was done by wet method with the use of nitric acid, hydrogen peroxide, and microwaves. The quantification of total mercury (THg) and total arsenic (TAs) was carried out by inductively coupled plasma optical emission spectrometry with vapor generation (VG-ICP OES). The methodology proposed by the U.S. Environmental Protection Agency was used. The results showed that TAs presents safe levels; however, THg presents a sample with levels up to (4.6 µg g 1), exceeding the permitted levels (1 µg g 1). The risk assessment shows that only the consumption of fish, linked to Hg, represents the existence of deleterious risks to indigenous peoples (hazard quotient (HQ)) > 1). Bioaccumulation factor (BAF) in fish represents a risk to indigenous people, because of the Hg’s presence. The study identified that illegal mining activities are responsible for Hg pollution in the Baú and Curuá Rivers. The fish species analyzed can be used as bioindicators of Hg in the rivers, which is relevant for making environmental and public health policy decisions.

https://doi.org/10.21577/0103-5053.20230072

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