Abstract Inflammatory bowel disease (IBD) is a problem that directly affects the quality of life of patients suffering from this condition. Monitoring the serum level of infliximab (IFX) (TDM) is an important tool for guiding therapeutic decisions in IBD patients. The purpose of this study was to determine the significance of quantitatively measuring the serum level of IFX (TDM) and antibody to IFX (ATI). Methods and materials: Prospective observational study involving 40 IBD patients on IFX therapy, including 14 Proactive (week 06 of the induction phase) and 26 Reactive (maintenance phase). Immediately prior to the infusion, blood samples were drawn and measured using a Bulhlmann rapid test instrument. Serum concentrations of IFX were categorized as supratherapeutic (>7.0 micrograms/ml), therapeutic (between 3.0 and 7.0 micrograms/ml), and subtherapeutic (3.0 micrograms/ml). When the serum concentration of IFX was 3 mcg/ml (subtherapeutic), the ATI was measured. 25 patients with CD and 15 patients with UC were evaluated. Only three of the twenty patients with subtherapeutic serum levels had a positive ATI, and both were reactive; two had CD and one had UC. There was a statistically significant difference between reactive and proactive patients with respect to levels of CRP (p = 0.042), with proactive DNS patients suffering greater alterations in CRP and albumin.

Resumo O artigo percorre as pesquisas sobre campesinato e questão agrária do antropólogo Moacir Palmeira para discutir como a mediação entre a assessoria sindical e a atividade acadêmica não foi de menos importância para suas formulações intelectuais sobre aqueles temas. Enquanto instâncias distintas de observação analítica e prática, essas atividades levaram Palmeira a uma compreensão mais ampla da questão agrária e dos impasses da democracia no Brasil.

Abstract This paper examines the studies on peasantry and the agrarian issue carried out by anthropologist Moacir Palmeira to discuss how the mediation between union counseling and academia was equally important for his intellectual formulations on those topics. As distinct instances of analytical and practical observation, these activities led Palmeira to a broader understanding of the agrarian issue and the impasses of democracy in Brazil.

ABSTRACT BACKGROUND: Breast cancer is a common neoplasm in women worldwide. Its varying patterns of incidence and clinical prognosis in Brazil make it an important and complex public health problem that needs to be solved. OBJECTIVES: To analyze the temporal dynamics of hospital admissions and deaths due to female breast cancer in the state of Alagoas, Brazil, from 2009 to 2019. DESIGN AND SETTING: Cross-sectional study including secondary data from hospital admissions and deaths due to female breast cancer in Alagoas. METHODS: A joinpoint regression model was constructed for temporal analysis of hospital admissions and deaths due to female breast cancer in Alagoas, over this period. The hospital information system of the Department of Informatics of the National Health System was used. RESULTS: There were 5,801 hospitalizations and 633 hospital deaths due to neoplasm in Alagoas over the period. The age group from 50 to 59 years old stood out, corresponding to 28.1% of hospitalizations and 31.1% of registered deaths. An increasing trend in the rate of hospital admissions was observed (average annual percentage change, AAPC = 14.0; P-value < 0.001), from 14.9/100,000 inhabitants in 2009 to 53.6 in 2019. There was a growth trend in the in-hospital mortality rate (AAPC = 19.8; P-value < 0.001), from 6.3% in 2009 to 11.0% in 2019. CONCLUSION: The results indicated an increasing trend of hospital admissions and mortality rates in the state of Alagoas, with a higher percentage of hospitalizations and deaths in the 50-59 age group.

Resumo: Introdução: A necessidade de levar informação visando combater a Covid-19 é ainda mais urgente nas regiões em desenvolvimento, uma vez que nesses locais há carência de recursos, supervisão governamental limitada, consideráveis índices de pobreza e dificuldade de acesso à informação. Com base na realidade da Transamazônica e do Xingu e na urgente necessidade da diminuição do número de casos da Covid-19 na região, a qual depende da adesão da população às medidas preventivas, surgiu o projeto de extensão “e-COVID Xingu: Mídias Sociais e Informação no Combate à COVID-19 em Altamira, Pará”. Este trabalho tem como objetivo descrever as experiências dos integrantes desse projeto durante a pandemia na região. Relato de Experiência: O projeto adotou como público-alvo a população do Xingu, em especial as comunidades indígenas e rurais. Publicações nas redes sociais levaram informações sobre medidas de prevenção, grupos de risco e isolamento social. Para alcançar as populações mais vulneráveis e que não possuem acesso à internet, uma parceria com a rádio local levou material informativo para a zona rural e comunidades indígenas afastadas. O projeto também lançou uma cartilha, em português e kayapó, com orientações de prevenção da Covid-19 para os indígenas do Médio Xingu. Discussão: Os informativos conseguiram bom alcance pelas redes sociais. Ademais, os meios de comunicação em massa, como o rádio, ainda se mostram eficazes na disseminação de informações. Com multiplataformas pode-se fazer educação em saúde inclusiva a diversos grupos sociais, seja pela internet, pelo rádio ou por materiais físicos. Conclusão: Utilizando múltiplas ferramentas de comunicação e respeitando o distanciamento social, a universidade, por meio de ação extensionista, pôde contribuir no combate à Covid-19, ao levar informações e conhecimento ao público, e atentar à necessidade de também incluir e informar populações histórica, social e economicamente vulneráveis, como indígenas e comunidade rurais do Xingu.

Abstract: Introduction: The need to provide information in the fight against COVID-19 is more urgent in developing regions, which suffer from insufficient resources, limited government supervision, high poverty rates and difficulty in accessing information. Considering the reality experienced by those living by the Transamazonian Highway and the Xingu River and the urgent need to reduce COVID-19 cases in the region, which depends on the population taking prevention measures, this community outreach project called “e-COVID Xingu: Social media and information against COVID-19 in Altamira, Pará” took shape. This article aims to describe the experiences of the project members in the initial months of the outreach project during the pandemic in the region. Experience Report: The project’s audience target was the population of the Xingu region, especially indigenous communities and those living in rural areas. While posts on social media spread information about prevention, risk groups and social isolation, in order to reach the most vulnerable people, who lack an internet connection, a partnership with a local TV and radio broadcaster provided important information to these remote indigenous villages and rural communities. Moreover, an informative booklet with guidance on how to prevent infection by COVID-19 was released in both Portuguese and the Kayapo language to raise awareness and understanding among Xingu indigenous communities. Discussion: The posts on social media achieved a good reach in social media. Furthermore, mass media, like radio, remain efficient information disseminators. The use of multiple tools is one possible way to educate diverse social groups, including the use of the internet, the radio or printed materials. Conclusion: Using different communication platforms and respecting social distancing, the university, through this community outreach project, was able to contribute to the fight against COVID-19, spreading accurate and safe information and considering the need to include historically, socially and economically vulnerable population groups such as the indigenous and rural Xingu communities.

ABSTRACT Introduction: A total of 57,960 new cases of breast cancer were expected in Brazil in 2016 according to data from the National Cancer Institute, corresponding to 25% of cancers in the country (excluding non-melanoma skin tumors). This study aims at presenting a surgical approach for immediate breast reconstructions with upper retropectoral and lower mixed subcutaneous cavities. Methods: The authors performed breast reconstruction using flaps of the pectoral muscle and inferior cutaneous pedicle associated with insertion of silicone breast implants. The medical records of patients operated between 2012 and 2016 at the Plastic Surgery Service of the senior author’s private clinic at Daher Hospital and Armed Forces Hospital were retrospectively analyzed. Results: The results were satisfactory, with low complication rates and high patient and author satisfaction. Thirty-six patients, with a mean age of 59 years, underwent breast reconstruction using the described technique. The complications were nipple-areola complex necrosis, dehiscence, seroma, hematoma, liponecrosis, implant displacement, and deep venous thrombosis. No patient needed salvage surgery or had recurrence of mammary neoplasia during the study period. Conclusion: The present technique preserves the skin located at the lower portion of the breast, with a low risk of dehiscence or extrusion of the implant in this region, providing a double protection of the implant, with the pectoralis major muscle in the upper two thirds and the cutaneous-dermis-fat flap in the lower third, characterizing a “dual-plane” positioning.

RESUMO Introdução: Segundo dados do Instituto Nacional de Câncer (INCA) de 2016, estima-se em 57.960 novos casos de câncer de mama no Brasil, o que corresponde a 25% dentre todos os tipos de cânceres no país (excluindo-se os tumores de pele não melanoma). O presente artigo visa apresentar uma forma de abordagem para as reconstruções mamárias imediatas com loja retropeitoral superior e subcutânea mista inferior. Métodos: Os autores descrevem da técnica de reconstrução mamária com retalho do músculo peitoral e pedículo cutâneo inferior, associado à inclusão de implante mamário de silicone. Foi realizada análise retrospectiva de prontuários das pacientes operadas entre os anos 2012 e 2016 no Serviço de Cirurgia Plástica da clínica privada do autor sênior, no Hospital Daher e no Hospital das Forças Armadas. Resultados: Os resultados são satisfatórios, com baixos índices de complicações e com satisfação elevada para os pacientes e os autores. Trinta e seis pacientes foram submetidas à reconstrução mamária com a técnica descrita, com média de idade de 59 anos. As complicações apresentadas foram necrose de complexo areolopapilar, deiscência, seroma, hematoma, liponecrose, deslocamento do implante e trombose venosa profunda. Nenhuma paciente teve necessidade de resgate da reconstrução ou apresentou recidiva da neoplasia mamária durante o período do estudo. Conclusão: Trata-se de técnica que preserva a pele da mama em sua parte inferior, com baixa possibilidade de deiscência ou extrusão do implante nesta região, proporcionando uma dupla proteção deste implante com o músculo peitoral maior nos dois terços superiores e o retalho cutâneodermogorduroso no terço inferior, caracterizando um “dual-plane”.

RESUMO O artigo identifica e discute alguns movimentos cognitivos cruciais da coleção Sociologia da revista DADOS. Inspirada em ideias sobre a dinâmica da diferenciação funcional da sociologia de Niklas Luhmann como uma chave geral de leitura dos dados da pesquisa, sugere o papel central que a sociologia política, especialidade mais recorrente, tem na coleção. Ela protagoniza um movimento simultâneo de diferenciação em relação ao conjunto dos artigos publicados e de modificação desse ambiente, pelas ressonâncias que vai imprimindo nas outras especialidades da sociologia. Nessa mesma chave, sugere o papel de autodescrição reflexiva em relação ao conjunto da coleção assumido pelo pensamento social e político, a segunda especialidade mais recorrente nesses 50 anos de publicação da revista.

ABSTRACT This article identifies and discusses several cognitive movements that are fundamental to DADOS journal sociology collection. Employing ideas on the dynamic of functional differentiation in the sociology of Niklas Luhmann as a general means of reading the survey data reveals the central role played by political sociology in the collection, which is the most common field of specialization. The discipline leads a movement which both differentiates itself from the rest of the articles published while altering the sphere, due to the resonances it imprints on the other specialist fields within sociology. Such a reading also highlights the role played in the collection by the reflexive self-description practiced by social and political thought, which has served as the second most common field of specialization over the 50 years since the journal’s first publication.

RESUMEN El artículo identifica y discute algunos movimientos cognitivos cruciales de la colección Sociología de la revista DADOS. Inspirada en ideas sobre la dinámica de la diferenciación funcional de la sociología de Niklas Luhmann como clave general de lectura de los datos de la investigación, sugiere el rol central que tiene la sociología política – especialidad más recurrente – en la colección. Ella protagoniza un movimiento simultáneo de diferenciación frente al conjunto de los artículos publicados y de modificación de ese ambiente, debido a las resonancias que imprime en las demás especialidades de la sociología. En esa misma clave, sugiere el rol de la autodescripción reflexiva frente al conjunto de la colección asumido por el pensamiento social y político, segunda especialidad más recurrente en los 50 años de publicación de la revista.

RÉSUMÉ L’article identifie et analyse certains mouvements cognitifs cruciaux de la collection Sociologie de la revue DADOS. En s’inspirant des idées sur la dynamique de la différenciation fonctionnelle de la sociologie de Niklas Luhmann comme grille de lecture des données de la recherche, on a identifié le rôle central joué par la sociologie politique dans la collection, où c’est d’ailleurs la spécialité la plus récurrente. Cette discipline est à la base d’un mouvement simultané de différenciation par rapport à l’ensemble des articles publiés, ainsi que d’une modification de cet environnement grâce aux résonnances qu’elle imprime aux autres spécialités de la sociologie. Selon cette même grille de lecture, on a pu analyser dans l’ensemble de la collection le rôle que joue l’auto-description réflexive dans la pensée sociale et politique, à savoir la seconde spécialité la plus présente dans la revue.

O artigo visa fornecer uma visão conjunta dos principais trabalhos da socióloga paulista Maria Isaura Pereira de Queiroz, buscando elucidar como os trabalhos de campo e os trabalhos mais teóricos da Autora articulam as dimensões micro e macro da vida social. Perspectiva que revela uma concepção essencialmente dinâmica da sociedade e dos aspectos criativos que envolvem as ações dos indivíduos, sendo por isso capaz de interpelar cognitivamente as ciências sociais contemporâneas.

The article aims to provide a joint view of the main work of the sociologist Maria Isaura Pereira de Queiroz, trying to elucidate how the field work and the most theoretical works of the Author articulate micro and macro dimensions of social life. A perspective that reveals an essentially dynamic conception of society and the creative aspects that involve the actions of individuals and is therefore able to cognitively challenge the contemporary social sciences.