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Reuse made by the separation of whey can reduce the waste of human milk. However, the authors are not aware of the literature on treatments in human whey, made available by pasteurization holder, freeze-drying, spray drying, and high hydrostatic pressure. In this context, the present study applied treatments to human whey and evaluated their lipid and immunological quality. Among the results, a different formation in the triacylglycerol profile was evidenced after the application of spray drying and high hydrostatic pressure, while pasteurization and freeze-drying presented ion intensity close to the control human whey. In addition, pasteurization proved to be adequate for lipid nutritional quality and transformation factor-β1 (TGF-β1) concentration, while an increase in interleukin-10 (IL-10) levels was promoted, between 73 and 80%, after freeze-drying, spray drying, and high hydrostatic pressure. Through the principal component analysis, it is noteworthy that the processes presented divergences in terms of the effects caused, with similarity only between pasteurization and freeze-drying in the composition of fatty acids. However, it was observed that all processes were able to maintain the nutrients. Nevertheless, it is relevant to consider individual characteristics presented and the interest in the desired quality, which can be promising as a complementary product to infant feeding.

https://doi.org/10.21577/0103-5053.20230102

Long-term oncological and surgical outcomes after Video Endoscopic Inguinal Lymphadenectomy (VEIL) in patients with penile cancer
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Tobias-Machado, Marcos

; Ornellas, Antonio A.

; Hidaka, Alexandre K.

; Medina, Luis G.

; Mattos, Pablo A. L.

; Besio, Ruben S.

; Abreu, Diego

; Castro, Pedro R.

; Nishimoto, Ricardo H.

; Astigueta, Juan

; Dourado, Aurus

; Machado, Roberto D.

; Magnabosco, Wesley J.

; Corona-Montes, Victor

; Villoldo, Gustavo M.

; Zampolli, Hamilton C.

; Taha, Anis

; Auad, Pericles R.

; Faria, Eliney F.

; Arantes, Paulo B. O.

; Tavares, Alessandro

; Nascimento, Francisco S. M. S.

; Brazão Jr., Eder S.

; Rocha, Maurício M.

; Costa, Walter H.

; Panico, Vinicius

; Reis, Leonardo O.

; Almeida-Carrera, Roberto J.

; Silva, Rafael C.

; Zequi, Stênio C.

; Calixto, José R. R.

; Sotelo, Rene

International braz j urol

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oct 2023, Volume 49 N. 5 Pages 580 - 589

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To report outcomes from the largest multicenter series of penile cancer patients undergoing video endoscopic inguinal lymphadenectomy (VEIL). Materials and Methods: Retrospective multicenter analysis. Authors of 21 centers from the Penile Cancer Collaborative Coalition-Latin America (PeC-LA) were included. All centers performed the procedure following the same previously described standardized technique. Inclusion criteria included penile cancer patients with no palpable lymph nodes and intermediate/high-risk disease and those with non-fixed palpable lymph nodes less than 4 cm in diameter. Categorical variables are shown as percentages and frequencies whereas continuous variables as mean and range. Results: From 2006 to 2020, 210 VEIL procedures were performed in 105 patients. Mean age was 58 (45-68) years old. Mean operative time was 90 minutes (60-120). Mean lymph node yield was 10 nodes (6-16). Complication rate was 15.7%, including severe complications in 1.9% of procedures. Lymphatic and skin complications were noted in 8.6 and 4.8% of patients, respectively. Histopathological analysis revealed lymph node involvement in 26.7% of patients with non-palpable nodes. Inguinal recurrence was observed in 2.8% of patients. 10y- overall survival was 74.2% and 10-y cancer specific survival was 84.8%. CSS for pN0, pN1, pN2 and pN3 were 100%, 82.4%, 72.7% and 9.1%, respectively. Conclusion: VEIL seems to offer appropriate long term oncological control with minimal morbidity. In the absence of non-invasive stratification measures such as dynamic sentinel node biopsy, VEIL emerged as the alternative for the management of non-bulky lymph nodes in penile cancer.

https://doi.org/10.1590/s1677-5538.ibju.2023.0065

Evaluation of the antinociceptive effect generated by citronellal monoterpene isomers
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Costa, A. O. C.

; Rego, R. I. A.

; Andrade, H. H. N.

; Costa, T. K. V. L.

; Salvadori, M. G. S. S.

; Almeida, R. N.

; Castro, R. D.

Brazilian Journal of Biology

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2023, Volume 83 elocation e271781

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Due to the complex nature of pain and the participation of physical, cognitive, psychological and behavioral aspects, pain management has several approaches. The use of medicinal plants in developing countries is quite expressive. Seeking new options for the treatment of emerging or debilitating diseases. Therefore, the present study seeks to elucidate the effects of the monoterpene, citronellal, differentiating its activity by isomers (R)-(+) and (S)-(-) citronellal. The study used several methods to evaluate the effects of citronellal isomers on motor coordination, nociceptive response, and the involvement of opioid, glutamatergic, and transient receptor pathways. The methods included rota-rod, hot-plate, and formalin tests, as well as the use of specific inhibitors and agonists. Data were analyzed using inferential statistics with a 95% confidence level. Both isomers did not significantly affect the motor coordination of the studied animals. The isomer (S)-(-) citronellal showed better results in relation to its structural counterpart, managing to have an antinociceptive effect in the formalin and hot plate tests with a lower concentration (100 mg/kg) and presenting fewer side effects, however, the this study was not able to elucidate the mechanism of action of this isomer despite having activity in studies with substances that act on specific targets such as glutamate and capsaicin, its activity was not reversed with the use of antagonists for pathways related to nociception. While the (R)-(+) citronellal isomer, despite showing total activity only at a concentration of 150 mg/kg, was able to determine its mechanism of action related to the opioid pathway by reversing its activity by the antagonist naloxone, being this is a pathway already correlated with nociception control treatments, however, it is also related to some unwanted side effects. In this way, new studies are sought to elucidate the mechanism related to the isomer (S)-(-) citronellal and a possibility of use in other areas related to the treatment of pain or inflammation.

Resumo Devido à natureza complexa da dor e a sua participação de aspectos físicos, cognitivos, psicológicos e comportamentais, o manejo da dor possui diversas abordagens. O uso de plantas medicinais em países em desenvolvimento é bastante expressivo. Buscando novas opções para o tratamento de denças emergentes ou debilitantes. Portanto, o presente estudo busca elucidar os efeitos do monoterpeno, citronelal, diferenciando sua atividade pelos isômeros (R)-(+) e (S)-(-) citronelal. O estudo utilizou diversos métodos para avaliar os efeitos dos isômeros de citronelal na coordenação motora, resposta nociceptiva e o envolvimento de vias opioides, glutamatérgicas e de receptores transitórios. Os métodos incluíram testes de rota-rod, placa quente e formalina, além do uso de inibidores e agonistas específicos. Os dados foram analisados estatisticamente com um intervalo de confiança de 95%. Ambos os isomeros não afetaram significativamente a coordenação motora dos animais em estudo. O isômero (S)-(-) citronelal apresentou melhores resultados em relação ao seu homólogo estrutural, conseguindo ter um efeito antinociceptivo nos testes de formalina e placa quente com menor concentração (100 mg/kg) e apresentando menos efeitos colaterais, entretanto, o presente estudo não foi capaz de elucidar o mecanismo de ação deste isomero apesar de ter atividadade em estudos com substancias que agem em alvos específicos como glutamato e capsaicina, sua atividade não foi revertida com a utilização de antagonistas para as vias relacionadas à nocicepção. Enquanto o isômero (R)-(+) citronelal, apesar de apresentar de apresentar total atividade somente na concentração de 150 mg/kg, foi capaz de determinar seu mecanismo de ação relacionado à via opióide pela reversão da sua atividade pelo antagonista naloxona, sendo esta uma via já correlacionada com os tratamentos de controle da a nocicepção, no entanto, também está relacionada a alguns efeitos colaterais indesejados. Desta forma busca-se novos estudos para elucidação do mecanismo relacionados ao isomero (S)-(-) citronellal e uma possibilidade de utilização em outras areas relacionadas ao tratamento da dor ou inflamação.

https://doi.org/10.1590/1519-6984.271781

The Impact of Compilation Flags and Choosing Single - or -Double-Precision Variables in Linear Systems Solvers
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BRUM, R. C.

; DE CASTRO, M. C. S.

; FARIA, C. O.

Trends in Computational and Applied Mathematics

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2023, Volume 24 N. 2 Pages 319 - 335

Abstract: En | Text: En | PDF: En

ABSTRACT This paper intends to show the impact of compiler optimization flags and the variable’s precision on direct methods to solve linear systems. The chosen six methods are simple direct methods, so our work could be a study for new researchers in this field. The methods are LU Decomposition, LDU Decomposition, Gaussian Elimination, Gauss-Jordan Elimination, Cholesky Decomposition, and QR Decomposition using the Gram-Schmidt orthogonalization process. Our study showed a huge difference in time between single-and double-precision in all methods, but the error encountered in the single-precision was not so high. Also, the best flags to these methods were the ‘-O3’ and the ‘-Ofast’ ones.

https://doi.org/10.5540/tcam.2023.024.02.00319

Comparative study of the doses of cytokinin in the quality of caigua (Cyclanthera pedata L.) in Peru
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Cruz Nieto, D. D.

; Castañeda Chirre, E. T.

; Castro Bartolomé, H. J.

; Legua Cárdenas, J. A.

; Nunja García, J. V.

; Vélez Chang, Y. J.

; Luque Vilca, O. M.

; Ito Díaz, R. R.

; Calizaya Llatasi, F. G.

; Leon Gomez, R.

; Maldonado Mamani, R. A.

Brazilian Journal of Biology

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2023, Volume 83 elocation e275635

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Bioavailability of nutrients, the scarcity of synthetic fertilisers, and the rising cost of fuel have all contributed to an increase in production costs, which has in turn reduced crop productivity and led scientists to seek out new methods to ensure high-quality output. In this context, various cytokinins dosages were tested in Peru to see whether they affected the quality of caigua, in an effort to address these issues. To mitigate these problems, a pot experiment was carried out to check the effects of various doses of cytokinin in the quality of caigua in Peru. The experiment consisted of 5 treatments including (0, 50, 100, 150 and 200 mL of cytokinin) by using (Anthesis Plus per 200 L of water) as a source, each with three replicates and placed following a randomized complete block design (RCBD). Treatment with 100 mL of cytokinins foliar analysis resulted in a caigua length of 18.9 cm, an increase in diameter of 5.65 cm, and an improvement in pulp thickness of 7.60 millimeters. Physiological parameters of caigua plants taken after 45 days of sowing were considerably improved with the same treatment. Similarly, N, K and Zn concentration in leaf was higher in case of 100 mL of cytokinins foliar analysis. Therefore, policymakers must advise using the recommended quantity of cytokinins to bring about regime transition, and formers can gain by injecting 100 mL of cytokinins to boost production and the economy. It was concluded that the adequate dose of cytokinins is in treatment T3, which raised value of potassium concentration in leaves, this influenced optimal development, strengthening against environmental stress and therefore quality. For this reason, research was carried out on the comparative study of cytokinin doses in the quality of caigua in Peru; the objective was to determine the appropriate dose to obtain higher quality fruit. Likewise, it was underlined that the objective was to employ an ecological alternative of plant origin such as the usage of phytohormone that stimulates the growth of the plant and consequently the quality of the fruit. The obtained the results were served as a recommendation for farmers in the area.

Resumo A biodisponibilidade de nutrientes, a escassez de fertilizantes sintéticos e o aumento do custo dos combustíveis contribuíram para um aumento nos custos de produção, o que, por sua vez, reduziu a produtividade das culturas e levou os cientistas a procurar novos métodos para garantir resultados de alta qualidade. Neste contexto, várias dosagens de citocininas foram testadas no Peru para examinar se afetavam a qualidade do caigua, num esforço para resolver estes problemas. Para mitigar esses problemas, foi realizado um experimento em vaso para verificar os efeitos de diversas doses de citocinina na qualidade do caigua no Peru. O experimento consistiu de cinco tratamentos, incluindo 0, 50, 100, 150 e 200 mL de citocinina utilizando Anthesis Plus por 200 L de água como fonte, cada um com três repetições e dispostos seguindo um delineamento em blocos completos casualizados (RCBD). O tratamento com 100 mL de análise foliar de citocininas resultou em comprimento de caigua de 18,9 cm, aumento de diâmetro de 5,65 cm e melhora na espessura da polpa de 7,60 mm. Os parâmetros fisiológicos das plantas de caigua colhidas após 45 dias da semeadura melhoraram consideravelmente com o mesmo tratamento. Da mesma forma, a concentração de N, K e Zn nas folhas foi maior no caso da análise foliar de 100 mL de citocininas. Portanto, os decisores políticos devem aconselhar a utilização da quantidade recomendada de citocininas para provocar a transição de regime, e os primeiros podem ganhar injetando 100 mL de citocininas para impulsionar a produção e a economia. Concluiu-se que a dose adequada de citocininas está no tratamento T3, que elevou o valor da concentração de potássio nas folhas, isso influenciou no desenvolvimento ideal, no fortalecimento contra o estresse ambiental e consequentemente na qualidade. Por esse motivo, foram realizadas pesquisas sobre o estudo comparativo de doses de citocinina na qualidade do caigua no Peru; o objetivo foi determinar a dose adequada para obter frutos de maior qualidade. Da mesma forma, foi sublinhado que o objetivo era empregar uma alternativa ecológica de origem vegetal, como a utilização de fito-hormona que estimulasse o crescimento da planta e, consequentemente, a qualidade do fruto. Os resultados obtidos serviram de recomendação para os agricultores da região.

https://doi.org/10.1590/1519-6984.275635

Influencia de la mineralización en propiedades mecánicas de las rocas de la mina Yaraguá en Buriticá - Antioquia, Colombia
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Acosta-Luna, Jheyson S.

; Suarez-Burgoa, Ludger O.

; Castro-Caicedo, Álvaro J.

; Molina-Escobar, Jorge M.

Boletín de Ciencias de la Tierra

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jun 2022, N. 51 Pages 23 - 37

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Se realizó una caracterización geomecánica de un túnel guía para la explotación de oro en la mina Yaraguá (Continental Gold Limited) en el Municipio de Buriticá (Antioquia). El proceso de caracterización comprendió la clasificación del macizo rocoso mediante los sistemas de clasificación RMR y Q, análisis de secciones delgadas, ensayos de velocidad de ondas P, carga puntual simple y resistencia a compresión uniaxial y triaxial. Las rocas analizadas se clasificaron como basaltos, andesitas, dioritas y brechas, todas con minerales como magnetita, carbonatos y de pirita. En los ensayos de velocidad de ondas, las rocas alcanzaron un 70% de la velocidad teórica, mostrando índices de continuidad que están en el intervalo de fuerte a intermedia. La resistencia a compresión uniaxial en el intervalo de 42 MPa y 134 MPa. El comportamiento de las rocas bajo las cargas en el ensayo de compresión triaxial muestra una tendencia frágil a frágil-dúctil y con una resistencia máxima en el intervalo de 130 MPa a 150 MPa. A partir de todos estos ensayos se determinó que hay dos tipos de fallamiento asociado a la mineralización: ya sea a través de venillas o por zonas de acumulación de sulfuros.

Abstract It was performed a geomechanically characterization of a guiding tunnel for the exploitation of gold in the Yaraguá mine (Continental Gold Limited) in the Municipality of Buriticá (Antioquia). The characterization process included the classification of the rock mass by the RMR and the Q systems, analysis of thin sections, tests such as the P-wave velocity, the point load test and the uniaxial and triaxial compression tests. The analyzed rocks classify as basalts, andesite, diorite and breccia, all with compound-minerals such as magnetite, carbonates and pyrite. In the wave velocity tests, the rocks have reached 70% of theoretical speed, giving continuity indices in the interval of strong to medium. The uniaxial compressive strength is between 42 MPa and 134 MPa. The behavior of the rocks under the loads in the triaxial compression test shows a fragile to fragile-ductile tendency and its peak resistance are in the interval from 130 MPa to 150 MPa. Finally, upon all these tests, one concludes that there are two types of failure associated with mineralization: either through veins or by sulphide accumulation zones.

https://doi.org/10.15446/rbct.n51.99326

The Neglected Role of Education in Brazilian Research Regarding Nuclear Theme versus Scientific and Technological Knowledge, Perception and Risk Communication
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AYLLÓN, RAFAELLA M.

; CASTRO, ALEX A.

; ROMERO, FERNANDA C.

; LEITE, LUIZ O. CERQUEIRA

; FARIAS, LUCIANA A.

Anais da Academia Brasileira de Ciências

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2022, Volume 94 N. 1 elocation e20200942

Abstract: En | Text: En | PDF: En

Abstract Studies of risk perception and risk communication concerning the nuclear area are quite common in scientific literature. However, though numerous studies on this topic point to the importance of scientific and technological knowledge in facilitating the reduction of perceived risks, there are few papers that effectively discuss the role of education in risk communication on the subject, particularly in Brazil. The objective of the present work was to reflect on this problem by analyzing the results obtained from two case studies on the implementation of the Brazilian Multipurpose Reactor, in the city of Iperó, in the state of São Paulo, Brazil. As was verified in the investigation, most participants of the study had high perception of risk with respect to the implementation of the reactor. Nevertheless, although important in the project of the reactor implementation, it was verified that the state, municipal and community schools of the city of Iperó had not participated, in the public hearings nor had they discussed the issue inside the school community, until the moment of the research.

https://doi.org/10.1590/0001-3765202220200942

10.

Identity of Gymnophthalmus (Squamata: Gymnophthalmidae) from northeastern Amazonia with evidence for G. underwoodi as invasive in Belém
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MACIEL, Adriano O.

; ARAÚJO, Ivanei S.

; LIMA-FILHO, Geraldo R.

; CASTRO, Felipe M. R.

; NASCIMENTO, Lywouty R. S.

; SANTOS, Manuela V. dos

; PRUDENTE, Ana L. C.

; STURARO, Marcelo J.

Acta Amazonica

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dec 2021, Volume 51 N. 4 Pages 291 - 297

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Nós relatamos a ocorrência do lagarto Gymnophthalmus underwoodi no município de Belém, estado do Pará, Brasil. Este é o primeiro registro ao sul do Rio Amazonas, provavelmente como resultado de uma introdução acidental por navios que atracam em Belém, o mesmo caminho sugerido para a introdução de outra espécie exótica de lagarto recentemente encontrada na cidade. Nós também determinamos a identidade de alguns espécimes de Gymnophthalmus dos estados do Amapá e Pará, através de dados morfológicos externos e moleculares, confirmando que, até o momento, G. vanzoi é o único Gymnophthalmus ocorrendo nos enclaves de savana desses estados. Por fim, nós fornecemos um novo mapa de distribuição para as espécies de Gymnophthalmus, incluindo o novo registro de ocorrência de G. underwoodi para o estado do Pará, onde ela pode ser considerada como uma espécie invasiva.

ABSTRACT We report the occurrence of the lizard Gymnophthalmus underwoodi in the municipality of Belém, state of Pará, Brazil. This is the first record of that species south of the Amazonas River, probably because of an accidental introduction by ships that dock in Belém, the same pathway suggested for the recent introduction of another species of exotic lizard recently recorded in the city. We also determined the identity of some specimens of Gymnophthalmus from the states of Amapá and Pará through external morphology and molecular data, confirming that, until now, G. vanzoi is the only Gymnophthalmus occurring in the savanna enclaves of those states. Finally, we provide a new distribution map for the species of Gymnophthalmus, including the new occurrence record for G. underwoodi for the state of Pará, where it can be considered as an invasive species.

https://doi.org/10.1590/1809-4392202101471

11.

Shelf Life of Bioactive Compounds from Acerola Pulp (Malpighia spp.) through Freeze-Drying and Microencapsulation
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Saqueti, Bruno H. F.

; Alves, Eloize S.

; Castro, Matheus C.

; Santos, Patrícia D. S. dos

; Sinosaki, Nayane B. M.

; Senes, Carlos E. R.

; Visentainer, Jesuí V.

; Santos, Oscar O.

Journal of the Brazilian Chemical Society

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oct 2021, Volume 32 N. 10 Pages 2009 - 2016

Abstract: En | Text: En | PDF: En

Acerola is a tropical fruit with a large industrial and commercial appeal due to its organoleptic qualities and bioactive compound-rich nature. Thus, as bioactive compounds (BC) stability is of great interest in the food industry, assessment of preserving techniques to prolong shelf life has become imperative. Hence, the purpose of this study was to evaluate how storage affects BC conservation in microencapsulated and lyophilized acerola pulps over 180 days. For this matter, antioxidant tests, physical-chemical analyzes, and vitamin C analysis by mass spectrometry were performed. Results indicated that microencapsulation better preserved the antioxidants in acerola pulp compared to the other preservation technologies employed. This is due to the greater BC concentration in the microencapsulated, as well as the pH reduction. Furthermore, over 180 days, microencapsulation better preserved the target compounds in acerola pulp compared to lyophilization, as evidenced by the superior content of BC in the former treatment, making it an appealing option for the food sector.

https://doi.org/10.21577/0103-5053.20210096 48 downloads

12.

Whey Isolation from Rejected Human Milk and Its Lipid Content Characterization by GC-FID and ESI-MS
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Alves, Eloize S.

; Castro, Matheus C.

; Saqueti, Bruno H. F.

; Manin, Luciana P.

; Silveira, Roberta da

; Souza, Patrícia M.

; Santos, Oscar O.

; Visentainer, Jesuí V.

Journal of the Brazilian Chemical Society

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sep 2021, Volume 32 N. 9 Pages 1884 - 1894

Abstract: En | Text: En | PDF: En

The present work intends to obtain and characterize a milk by-product: the human whey (HW), in order to avoid the excessive disposal of human milk (HM). The characterization was performed through analyzes of the chemical composition and fatty acids (FAs) and the triacylglycerol (TAG) lipid profile. The results indicated that the chemical composition altered significantly after the HW obtained, except for the percentage of ash and carbohydrates. About the FA composition, it was observed that strictly essential FA, essential FA and other FAs found in HM remained present in HW. For the nutritional lipids quality, the atherogenicity and the thrombogenicity indices presented desirable values, and the TAGs lipid profile revealed a variation in the analyzed samples. Therefore, it can be concluded that the characterized HW has potential for application in isolated form or to be used as an ingredient in other foods.

https://doi.org/10.21577/0103-5053.20210092 32 downloads

13.

Revista Alconpat: 10 years of history (2011 - 2021)
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Castro-Borges, P.

; Sabido-Maldonado, E.

; Mendoza-Rangel, J. M.

; Helene, P.

; Garcés-Terradillos, P.

; Torres-Acosta, A. A.

; Fernández-Cánovas, M.

; Husni, R.

; Troconis-Rincón, O.

; Branco, F.

; Escalante-García, J. I.

; Alonso-Farrera, F.

; Olavarrieta-Parisot, M. A.

Revista ALCONPAT

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aug 2021, Volume 11 N. 2 Pages 146 - 157

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract The objective of this paper is to present to the community the achievements attained and the challenges, met, current and coming, during the first ten years of existence of the Alconpat Journal. A narration is made of: how the idea of having a scientific/technical journal in Alconpat International arose; when, how and where the discussions and the project took place; the implementation, the first issue, the punctuality; the requirements and challenges to meet for the first indexations (Scielo México, Scielo WoS, Redalyc, Latindex, Google); the Conacyt projects that made it possible to gradually meet the requirements for eventual applications at higher indexes (Scopus and WoS), repositories, directories (DOAJ) and super servers; electronic markings, publication in three languages (Spanish, Portuguese and English), administrative times for timely publication, etc. The efforts of all those who have collaborated in these initial 10 years are also acknowledged.

Resumen El objetivo de este trabajo es presentar a la comunidad los logros y retos por venir de la Revista Alconpat en sus primeros diez años de existencia. Se realiza una narración de: cómo surgió la idea de tener una revista científico/técnica en Alconpat Internacional; cuando, como y donde se llevaron a cabo las discusiones y el proyecto; la implementación, el primer número, la puntualidad; los requisitos y retos a cumplir para las primeras indizaciones (Scielo México, Scielo WoS, Redalyc, Latindex, Google); los proyectos CONACyT que permitieron cumplir poco a poco los requisitos para eventuales aplicaciones a índices superiores (Scopus y WoS), repositorios, directorios (DOAJ) y super servidores; marcaciones electrónicas, publicación en tres idiomas (español, portugués e inglés), los tiempos administrativos para publicación puntual, etc. Al final se hace un extenso agradecimiento a todos los que han intervenido en estos 10 años iniciales.

Resumo O objetivo deste trabalho é apresentar à comunidade as conquistas e desafios da Revista Alconpat em seus primeiros dez anos de existência. Narra-se: como surgiu a ideia de uma revista científica / técnica na Alconpat Internacional; quando, como e onde as discussões e o projeto ocorreram; como foi a implementação, a primeira questão, a pontualidade; os requisitos e desafios a cumprir para as primeiras indexações (Scielo México, Scielo WoS, Redalyc, Latindex, Google); os projetos do CONACyT que possibilitaram atender gradativamente os requisitos para eventuais aplicações em índices superiores (Scopus e WoS), repositórios, diretórios (DOAJ) e super servidores; marcações eletrônicas, publicação em três idiomas (espanhol, português e inglês), tempos administrativos para publicação específica, etc. Ao final, um extenso agradecimento a todos aqueles que participaram desses primeiros 10 anos.

https://doi.org/10.21041/ra.v11i2.534 15 downloads

14.

Plantas medicinales de los Tének de San Francisco, Chontla, Veracruz, México
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Castro Guzmán, S.

; Cano Asseleih, L. M.

; Sánchez Sánchez, O.

Polibotánica

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2021, N. 52 Pages 213 - 239

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: The Veracruz State has a great floristic and cultural wealth that has allowed the development of herbal knowledge. Nowadays there are a lot of studies that record the medicinal use of the plants. Nevertheless, there are insufficient or even null information about some segregated geographic areas and even of some native cultures of the region. That is the scenario of the Huasteca and Tének regions, located at the northeast of the State. Even with his vast knowledge and traditions about herbology and as practicing herbalists, there has been no approach to them in this area. The main goal of this research is to contribute to the understanding of the Tének culture through the documentation of his herbal traditional practices on the San Francisco community (at the Chontla Municipality). We documented the use of most required medicinal species by the population, trough open and semi structured interviews to the three most prestigious and recognized Traditional Herbalist (TH). With the support of this TH we collected and identify botanical specimens on the field. Of the six species that all the three TH mentioned, we collected the 10% of the knowledge of the population about them (we did it establishing ranges of ages). Also, we determined the cultural significance due to a fidelity index (FI), which includes the priority range (PR) and the relative popularity (RP). What´s more, the value index for the use of morphologic structures of the used plants was calculated. A total of 97 medicinal species (in which 53 families and 84 genders are included) were documented. It was found about 8 new botanical records on the Medicinal Flora of the State of Veracruz. We can conclude that the research document and probe the importance and knowledge generated through the management and use of the medicinal plants in the Tének community of San Francisco Chontla, Veracruz.

Resumen: El estado de Veracruz cuenta con una gran riqueza florística y cultural que ha permitido el desarrollo de un vasto conocimiento herbolario. Si bien existen diversos estudios que registran el uso medicinal de las plantas, aún quedan áreas geográficas y culturas autóctonas con escasa o nula información. Este es el caso de la Región Tének o Huasteca ubicada al noreste del Estado, que a pesar de la gran tradición que han tenido como médicos tradicionales y conocedores de la herbolaria, el acercamiento a esta etnia ha sido casi nulo en este rublo. El objetivo de esta investigación es contribuir al conocimiento de la cultura Tének de Veracruz, a través de la documentación de la herbolaria tradicional en la comunidad de San Francisco, del Municipio de Chontla. Mediante entrevistas abiertas y semiestructuradas a los tres médicos tradicionales (MT) de mayor prestigio en la comunidad, se documentó el uso de las especies medicinales utilizadas por ellos, con base a la demanda de atención de los pobladores. A través de recorridos en compañía de los MT, se recolectaron las especies en campo e identificaron botánicamente. De las siete especies que los médicos tradicionales coincidieron en mencionar, se determinó en el 10% de la población, por rangos de edad, el conocimiento que existe sobre ellas. Se determinaron también, la significancia cultural mediante el índice de fidelidad (FL), que incluye el rango de prioridad (ROP) y la popularidad relativa (RPL). Además, se calculó el índice de valor de uso para las estructuras morfológicas de las plantas utilizadas. Se documentaron un total de 97 especies medicinales las que se incluyen en 53 familias y 84 géneros. Se encontraron ocho nuevos registros a la Flora Medicinal de Veracruz. Los resultados de la investigación documentan y demuestran la riqueza florística y cultural en relación al conocimiento, uso y manejo de plantas medicinales en la comunidad Tének, de San Francisco Chontla, Veracruz.

https://doi.org/10.18387/polibotanica.52.14 107 downloads

15.

Nuclear and mitochondrial genome instability induced by fractions of ethanolic extract from Hovenia dulcis Thunberg in Saccharomyces cerevisiae strains
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ARAÚJO, LUANA B.N. DE

; CAL, BRUNA B.F.

; NUNES, BRENO M.

; CRUZ, LETICIA O. DA

; SILVA, CLAUDIA R. DA

; CASTRO, TATIANA C. DE

; LEITÃO, ÁLVARO C.

; PÁDULA, MARCELO DE

; ALBARELLO, NORMA

; DANTAS, FLAVIO J.S.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 N. 3 elocation e20191436

Abstract: En | Text: En | PDF: En

Abstract Hovenia dulcis is a plant commonly used as a pharmaceutical supplement, having displayed important pharmacological properties such antigiardic, antineoplastic and hepatoprotective. The purpose of this work was investigate the cytotoxic, genotoxic and mutagenic potential from fractions of Hovenia dulcis ethanolic extract on Saccharomyces cerevisiae strains FF18733 (wild type) and CD138 (ogg1). Ethanolic extract from Hovenia dulcis leaves was fractioned using organic solvents according to increasing polarity: Hexane (1:1), dichlorometane (1:1), ethyl acetate (1:1) and butanol (1:1). Three experimental assays were performed, such as (i) inactivation of cultures; (ii) mutagenesis (canavanine resistance system) and (iii) loss of mitochondrial function (petites colonies). The findings shown a decrease in cell viability in FF18733 and CD138 strains; all fractions of the extract were mutagenic in CD138 strain; only ethyl acetate and butanol fractions increased the rate of petites colonies for CD138 strains. Ethyl acetate and n-butanol fractions induces mutagenicity, at the evaluated concentrations, in mitochondrial and genomic DNA in CD138 strain, mediated by oxidative lesions. In conclusion, it is possible to infer that the lesions caused by the extract fractions could be mediated by reactive oxygen species and might reach multiple molecular targets to cause cellular damage.

https://doi.org/10.1590/0001-3765202120191436 177 downloads

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