Objective to analyze the circumstances of falls reported in a high-complexity university hospital. Method a descriptive study with a quantitative approach, conducted in a university hospital. Data collection was performed from January 2015 to July 2016, using the secondary data, and in October 2016. The median was calculated for continuous variables with non-normal distribution and frequencies and proportions were calculated for categorical variables. Results the incidence rate of falls was 2.21% per month. Falls were more frequent in the age group 60 years old or older (42.86%) and 20 to 59 years old (70.00%), in the morning shift (47.37%) and in people with diseases’s circulatory system (35.71%). The professionals who most reported falls were nurses. Conclusion the circumstances of falls reported in a high-complexity university hospital were assessed in most cases and were more frequent in male patients, aged 60 years old or older, with cardiovascular disease, using antihypertensive drugs and diuretics. In addition, it was noted that there is potentially underreporting of falls in the institution.

Objetivo analizar las circunstancias de las caídas notificadas en un hospital universitario de alta complejidad. Método estudio descriptivo con enfoque cuantitativo realizado en un hospital universitario. Los datos se recolectaron de enero de 2015 a julio de 2016, por medio de los datos secundarios, y en octubre de 2016. Se calculó la mediana para las variables continuas con distribución no normal, y se calcularon frecuencias y proporciones para las variables categóricas. Resultados el índice de incidencia de caídas fue de 2,21% por mes. Las caídas fueron más frecuentes en los grupos etarios de 60 años o más (42,86%) y de 20 a 59 años (70,00%), en el turno de la mañana (47,37% y 60,00%) y en personas con enfermedades cardiovasculares (35,71%). Los profesionales que notificaron más caídas fueron los enfermeros. Conclusión las circunstancias de las caídas notificadas en un hospital universitario de alta complejidad se evaluaron en la mayoría de los casos, y fueron más frecuentes en pacientes de sexo masculino, de al menos 60 años, con enfermedades cardiovasculares, y en tratamiento con anti-hipertensivos y diuréticos. Además, se notó que existe un potencial de subnotificación de caídas en la institución.

Objetivo analisar as circunstâncias das quedas notificadas em um hospital universitário de alta complexidade. Método estudo descritivo, com abordagem quantitativa, realizado em um hospital universitário. A coleta de dados foi realizada de janeiro de 2015 a julho de 2016, por meio dos dados secundários, e em outubro de 2016. A mediana foi calculada para as variáveis contínuas com distribuição não normal e as frequências e proporções foram calculadas para as variáveis categóricas. Resultados a taxa de incidência de quedas foi de 2,21% ao mês. Considerando os dois momentos de coleta, respectivamente, as quedas foram mais frequentes na faixa-etária de 60 anos ou mais (42,86%) e 20 a 59 anos (70,00%), no turno da manhã (47,37% e 60,00%) e em pessoas com doenças cardiovasculares (35,71%). Os profissionais que mais notificaram quedas foram enfermeiros. Conclusão as circunstâncias das quedas notificadas em um hospital universitário de alta complexidade foram avaliadas na maioria dos casos e foram mais frequentes em pacientes do sexo masculino, com 60 anos ou mais, com doenças cardiovasculares, em uso de anti-hipertensivos e diuréticos. Além disso, notou-se que potencialmente existe subnotificação de quedas na instituição.

OBJECTIVES: Inflammatory molecules play a role in the development of atherosclerosis, which is the primary origin of cardiovascular disorders. However, to the best of our knowledge, no study has attempted to investigate the relationship between these circulating molecules and the prediction of cardiovascular risk. The present study aimed to investigate the relationships of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 serum concentrations with the extent of coronary lesions. METHODS: Seventy-four individuals who were undergoing coronary angiography for the first time for diagnostic purposes were enrolled in this study. The extent of the coronary lesion was assessed using the Friesinger Index, and subjects were classified into four groups: no lesions, minor lesions, intermediate lesions and major lesions. Serum biochemical parameters and serum concentrations of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 were analyzed. RESULTS: The vascular cell adhesion molecule-1 concentration was higher than 876 ng/mL in individuals with intermediate and major lesions (p<0.001 and p=0.020, respectively). Moreover, logistic regression analysis showed that these patients had an increased risk of having an intermediate lesion (p=0.007). Interestingly, all individuals with major lesions had vascular cell adhesion molecule-1 concentrations higher than 876 ng/mL. No association was found between the concentrations of the other proteins and the Friesinger Index. CONCLUSIONS: Serum vascular cell adhesion molecule-1 may be associated with the extent of coronary lesions. Moreover, it may represent an alternative to improve the cardiovascular risk classification in patients without acute coronary syndrome.

ABSTRACT Chronic kidney disease (CKD) increases cardiovascular disease (CVD) risk development. However, the mechanisms of reduced kidney function with CVD risk are unclear. This study aimed to investigate the association between kidney function and Framingham risk score (FRS) in participants with traditional cardiovascular risk factors and normal estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m² in an admixed population of Brazil. The participants were divided into three groups according to FRS: low risk group with 0% to <10%, moderate risk group with ≥10% to 20% and high risk group with >20%. The eGFR was calculated using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Data from participants were collected by questionnaire, and blood and urine samples were collected to analyze biochemical markers. A total of 214 subjects aged 53±10 years old was collected. There were 77 individuals in low risk group, 59 in moderate risk group and 78 in high-risk group. Mean eGFRCKD-EPI was 89.39±15.05 mL/min/1.73 m² and 90.74±16.17 mL/min/1.73 m2 when race adjustment. The results indicated that there is an increasing the cardiovascular risk with a decreased of eGFR, conforming to a significant inverse correlation observed between eGFR and FRS with Spearman correlation (R²=-0.256, p<0.001; R²=-0.224, p=0.001, when adjusted for race). There was a statistically significant difference in eGFRCKD-EPI (p<0.001) and eGFRCKD-EPI with race adjustment (p=0.002) among risk groups. The data suggests that the reduction eGFR is associated with elevated FRS among Brazilian adults without CKD. Furthermore, the results suggest that race adjustment it’s not necessary in Brazilian population.

O objetivo deste trabalho foi definir o tipo de substrato e a temperatura mais adequada à germinação de sementes de Dalbergia nigra (Vell.) Fr. All. Ex Benth (jacarandá-da-bahia), e conhecer a morfologia de seu desenvolvimento pós-seminal e caracterizar as plântulas normais, o tipo de germinação e os padrões de anormalidade. As sementes foram semeadas nos substratos sobre papel, rolo de papel e sobre vermiculita, nas temperaturas constantes de 20, 25, 30 e 35°C e alternadas de 20-30°C e 20-35°C. O delineamento estatístico empregado foi o inteiramente casualizado (6x3), com quatro repetições de 50 sementes. Foram analisados os seguintes parâmetros: porcentagem de germinação normal (plântulas normais) e velocidade de emergência de plântulas. Os melhores resultados foram verificados nas temperaturas de 25°C e 20-30°C, nos substratos sobre vermiculita e rolo de papel. Plântulas normais foram caracterizadas como faneroepígeas em relação ao tipo de germinação.

The objective of this work was to define the germination substrate of Dalbergia nigra (Vell.) Fr. All. Ex Benth (jacarandá-da-bahia), to evaluate the most appropriate temperature for its seeds germination, and to study its post-seminal morphology, showing normal and abnormal seedlings patterns. Seeds were sowed on filter paper, towel paper and vermiculite, using the constant temperatures of 20, 25, 30 and 35°C as well as alternate temperatures of 20-30°C and 20-35°C. The statistical design was completely randomized (6x3) with 50 seeds sowed in four replications in which the following parameters were analyzed: normal germination (normal seedlings) percentage and speed emergence index. The best results were obtained for temperatures of 25°C and 20-30°C in vermiculite and towel paper substrates. Normal seedlings were classified as faneroepigeal germination type.