Abstract This systematic review and meta-analysis aimed to analyze the impact of the COVID-19 pandemic on dental trauma patient attendance. The study was registered in the PROSPERO system, using the CRD42021288398 protocol. Searching was performed in PubMed, Scopus, Web of Science, Embase, Lilacs, and OpenGrey databases, using the following keywords: “Tooth injuries,” “Dental trauma,” “Traumatic Dental injury,” and “COVID-19". We included observational studies evaluating dental trauma in the context of the COVID-19 pandemic. Quality assessment was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Cross-Sectional Studies. Meta-analysis was performed in RevMan 5.4 software with Odds Ratios as a pooled measure of effect, with a 95% confidence interval, and using random-effects modeling. After applying the eligibility criteria, 32 studies were included for qualitative analysis, in which 10 were used to assess the frequency of dental trauma diagnoses in dental emergencies. Despite the decrease of visits during COVID-19, the analysis revealed no difference between the pandemic and pre-pandemic periods. Regarding the type of dental trauma, two of the studies revealed no differences for the periods before and during the pandemic. This study revealed that the COVID-19 pandemic has not impacted the frequency or type of dental trauma compared to previous periods.

ABSTRACT Objective: The objective of the study was to assess the association of anthropometric measurements with endothelial function and arterial stiffness of eutrophic individuals and with overweight. Subjects and methods: A cross-sectional study was carried out with individuals with body mass index (BMI) between 18.5 kg/m² and < 30 kg/m², low to intermediate global cardiovascular risk scores, and aged ≥ 18 and < 60 years. We assessed the sociodemographic data, anthropometric variables (body weight, height, circumferences of the waist [WC], neck [NC], hip [HC], sagittal abdominal diameter [SAD], [BMI], waist-to-hip ratio [WHR], and waist-to-height ratio [WHtR]), biochemical parameters (lipid profile and nitric oxide), endothelial function (flow-mediated dilation [FMD], by ultrasound), and arterial stiffness (pulse wave velocity [PWV] and the amplification index [AIx@75] by oscillometry). Thirty-six individuals were included, 18 eutrophic and 18 with overweight, with a mean age of 37.5 ± 10.2 years, mostly at low cardiovascular risk (86.1%), female (80.6%), single (52.8%), employed with formal contracts (44.4%), and with over twelve years of education (88.9%). Results: The PWV presented positive and moderate correlation with the WC (r = 0.584; P = 0.001), WHR (r = 0.513; P = 0.001), and WHtR (r = 0.590; P = 0.001), and positive and low correlation with the NC (r = 0.372; P = 0.013) and SAD (r = 0.356; P = 0.033). Moreover, no anthropometric parameter presented a correlation with the AIx@75 or the FMD percentage in the total sample. Conclusion: Our findings show that in eutrophic individuals and with overweight the WC, WHR, WHtR, SAD, and NC were positively correlated with the PWV but not to the endothelial function in the overall sample. These are hypothesis-generating findings and they should be replicated in other studies.

Resumo As Brachiaria sp contêm esporidesminas que podem ser oxidadas por lipoperoxidação e ocasionar estresse oxidativo. No presente estudo foram avaliados os efeitos de diferentes antioxidantes na lipoperoxidação dos eritrócitos de bovinos da raça Nelore, alimentados com feno de Brachiaria sp. O delineamento experimental foi inteiramente casualizado, em que 40 bovinos machos, inteiros, foram divididos, em cinco tratamentos (G1: controle - sem suplementação; G2: suplementação de selênio e vitamina E; G3: suplementação de zinco; G4: suplementação de selênio e G5: suplementação de vitamina E) e alocados em baias de confinamento, por 105 dias. As amostras de plasma heparinizado ou com ácido etilenodiamino tetra-acético (EDTA) foram obtidas a cada 28 dias para avaliação hematológica e de estresse oxidativo (0, 28 56, 84 e 105 dias). No eritrograma foi mensurado a contagem total de eritrócitos, a hemoglobina e o volume globular (VG). Para a avaliação do estresse oxidativo, com o objetivo de analisar as características da membrana do eritrócito foram determinadas as substâncias reativas ao ácido tiobarbitúrico (TBARS), glutationa total (GSH-T), glutationa peroxidase (GSH-Px), catalase (CAT) e superóxido dismutase (SOD). Os resultados demonstraram que independente do tratamento não houve estresse oxidativo durante o período do confinamento experimental e que a associação conjunta de selênio e vitamina E na dieta dos bovinos proporcionaram menor incidência de alterações deletérias sobre os eritrócitos.

Abstract Brachiaria sp contains sporidesmin that can be oxidized by lipoperoxidation and cause oxidative stress. In the present study we evaluated the effects of different antioxidants on lipoperoxidation of erythrocytes from Nelore cattle fed with Brachiaria sp hay. The experimental design was entirely randomized, in which 40 whole male cattle were divided into five treatments (G1: control - no supplementation; G2: selenium and vitamin E supplementation; G3: zinc supplementation; G4: selenium supplementation and G5: vitamin E supplementation) and allocated in feedlot pens for 105 days. The samples heparinized and withethylenediaminetetraacetic acid (EDTA) were obtained every 28 days for hematological and oxidative stress evaluation (0, 28 56, 84 and 105 days). In the erythrogram total erythrocyte count, hemoglobin, and hematocrit (Ht) were measured. For the evaluation of oxidative stress, in order to analyze the characteristics of the erythrocyte membrane, the thiobarbituric acid reactive substances (TBARS), total glutathione (GSH-T), glutathione peroxidase (GSH-Px), catalase (CAT) and superoxide dismutase (SOD) were determined. The results showed that regardless of the treatment there was no oxidative stress during the experimental confinement period and that the joint association of selenium and vitamin E in the bovine diet provided a lower incidence of deleterious alterations on erythrocytes.

Objective: To analyze possible correlations among tubular dentine cement penetration, adhesiveness and apical leakage in fillings performed with gutta percha and an endodontic cement based on epoxy amine resin. Material and Methods: Sixty similar, extracted human mandibular central incisors were irrigated, instrumented and filled following the same protocol. First, apical leakage was quantified by fluid filtration tests. Then, these same specimens were sectioned for analysis of tubular dentine cement penetration and the middle thirds were submitted to push-out tests to analyze the adhesiveness of the fillings. Results: In brief, the means and standard deviations with a confidence interval of 95% were as follows: tubular dentine cement penetration (8.875±4.540), adhesiveness (4.441±2.683) and apical leakage (0.318±0.215). The data were confronted using the Pearson's test (P>0.05), and it was possible to prove that there was no correlation between (1) tubular dentine cement penetration and apical leakage (r2: 0.08276), (2) tubular dentine cement penetration and adhesiveness (r2: -0.2412) and (3) adhesiveness and apical leakage (r2: 0.1340). Conclusion: After analysis of these data, it could be observed that there exists no correlation among the variables analyzed in this study.

The aim of this paper was to evaluate a possible correlation between obturation limits and leakage. Thirty-six extracted human mandibular incisors were used, characterized by straight and single canals, non-anatomical complexities, absence of previous endodontic treatment, complete root formation and patent foramen. For standardization of the specimens for the leakage analysis, foraminal instrumentation was performed up to a Flexofile #25 (Dentsply-Maillefer, Ballaigues, Switzerland). All specimens were instrumented and filled following the same protocol, and the obturation limits were measured using Axiovision 4.5 Software (Carl Zeiss Vision, Hallbergmoos, Germany). The specimens were then separated into three groups (n = 12) according to the following variables: Group I - obturation limits ranging from 0 mm to 0.76 mm of the main apical foramen. Group II - obturation limits ranging from 0.77 mm to 0.98 mm of the main apical foramen. Group III - obturation limits ranging from 0.99 mm to 1.68 mm of the main apical foramen. Apical leakage was quantified by fluid filtration. The analyses were confronted using Pearson's test (p > 0.05). Groups I, II and III showed Pearson correlation values (r2) of -0.152, -0.186 and 0.058, respectively. No correlation was found between the obturation limits and apical leakage

The new dibromotyrosine derivative 3,5-dibromo-4-[3'dimethylamonium]propoxyphenyl]-N,N,N-trimethylethanamonium, here referred to as aplysfistularine (1), was isolated from the marine sponge Aplysina fistularis along with 2-(3,5-dibromo-4methoxyphenyl)-N,N,N-trimethylethanamonium (2), aplysterol (3) and 24,28-didehydroaplysterol (4). Their identification was performed by mass spectrometry, infrared, ¹H and 13C NMR, and by comparison with literature data. Compound 2 and the mixture of 3 and 4 were tested in vitro (inhibitory activity) with supercoiled DNA relaxation techniques, and showed inhibitory activity on human DNA topoisomerase II-α. Compound 1 was not tested due to paucity of the material.

O objetivo deste trabalho foi comparar valores estimados obtidos por amostragem com os valores verdadeiros registrados no Censo Florestal (inventário 100%) de uma área de floresta na Amazônia. Foi simulada uma amostragem sistemática, atendendo às exigências do IBAMA (BRASIL, 2007), com unidades amostrais de 2 ha e intensidade amostral de 14% em uma área de 1.000 ha, que foi submetida a um Censo Florestal. Neste e na simulação do inventário florestal, consideraram-se apenas a população com DAP > 40 cm e uma lista de 60 espécies que foram identificadas como a população de árvores consideradas de valor comercial. Foram avaliados os desvios da abundância, da área basal e do volume por hectare da amostragem em relação à população. Os desvios foram avaliados em relação às espécies individualmente e às espécies agrupadas, de acordo com a classificação de preço utilizada pelo Serviço Florestal Brasileiro. Também foram avaliados os desvios por classe de diâmetro, por grupo e para o total da população. Mesmo com intensidade amostral de 14%, seis espécies (10%) não foram registradas na amostra, resultando em desvios de 614% para mais e 100% para menos em relação à abundância, à área basal e ao volume.

The aim of this work was to compare the estimated values obtained by sampling with the actual values recorded in the Forest Census (inventory 100%) of a forest area in the Amazon. A systematic sampling was simulated, attending the requirements of IBAMA, with 2-ha sample units and sampling intensity of 14% in a 1,000-ha area, which was subjected to a forestry census. The census and simulation of forest inventory considered only the population with DBH > 40 cm and a list of 60 species which were identified as the population of trees considered of commercial value. It was evaluated the deviations of abundance, basal area and volume per hectare of sampling in relation to population. Deviations were evaluated with respect to individual species and species grouped according to the classification of price used by the Brazilian Forest Service. Deviations were also evaluated by diameter class, by group, and the total population. Even with sampling intensity of 14%, six species (10%) were not recorded in the sample, resulting in deviations from more than 614% to more and 100% to less in relation to abundance, basal area and volume.

A madeira por ser um material de origem orgânica responde de várias maneiras aos diversos produtos nela empregados, inclusive a aplicação de cola a qual depende do seu teor de umidade, tendendo a atingir um teor de umidade em equilíbrio dinâmico com a umidade relativa da atmosfera. Atualmente utilizam-se lâminas com teores de umidade entre 5 e 15% de acordo com o tipo de resina utilizada. O presente estudo avaliou o efeito de 04 gramaturas (270; 330; 364 e 390 g/m²) na produção de painéis compensados utilizando as espécies: Copaifera duckei Dawyer e Eperua oleifera Ducke. As espécies utilizadas foram retiradas da área de manejo florestal sustentável da Gethal Indústria de Madeira Compensada Ltda localizada em Manicoré-Am. As lâminas foram produzidas com espessuras de 2,2 mm. As variáveis do ciclo de prensagem foram controladas seguindo as orientações técnicas estabelecidas pelo fabricante da resina. Foi avaliada a resistência da linha de cola, com amostras da capa e do miolo em condições seca e pós-fervura. Para análise estatística foi aplicado um delineamento inteiramente casualizado com arranjo em esquema fatorial dos tratamentos. Confrontando os valores médios da tensão de ruptura e a percentagem de falha na madeira obtidos nesta pesquisa, ensaio seco e pós-fervura, com os da literatura, foi verificado que os painéis avaliados atendem aos critérios estabelecidos, podendo ser indicados para uso interior e exterior, pois de acordo com a Norma EN 314-2 (1993) o valor médio da tensão de ruptura em conjunto com a porcentagem de falha na madeira encontram-se em um padrão aceitável de comportamento.

The wood as a source of organic material responds in different ways to different treatments her employees, including the application of glue which depends on its moisture content, tending to reach a moisture content in dynamic equilibrium with relative humidity of the atmosphere. Currently we use blades with moisture levels of between 5 and 15% according to the type of resin used. This study evaluated the effect of 04 weights (270, 330, 364 and 390 g/m²) in the production of panels using offset the species: Copaifera ducker Dawyer and Eperua oleifera Ducke. The species were removed from the area of sustainable forest management Gethal Plywood Industry Ltd. located in Manicoré-Am. The slides were produced with thickness of 2.2 mm. The variables of the pressing cycle of were controlled by following the technical guidelines set by the manufacturer of resin. The property was assessed to resilience of the line of glue, with samples of the hood and the kernels in drought conditions and post-boil. Statistical analysis was applied an experimental design with in a factorial arrangement of treatments. Confronting the average values of voltage collapse and the percentage of failure in wood obtained in this research, test and post-boiling dry, with the literature, it appears that the panels assessed meet the established criteria, may be indicated for use inside and outside Because according to EN 314-2 (1993) the average voltage collapse along with the percentage of failure in the wood are at an acceptable standard of behavior.

RESUMO Esta pesquisa se originou de uma base de dados de dois inventários a 100% realizados em 1984 e 2000 sobre uma mesma área de 576 ha de floresta tropical primária, localizada na Floresta Nacional do Tapajós, Belterra, Pará. A pesquisa objetivou avaliar a evolução da estrutura diamétrica de seis espécies comerciais de terra firme da Amazônia no período 1984-2000 e projetá-la para 2016, utilizando-se de matriz de transição. Nos dois inventários, as CAP foram medidas com fita métrica, sendo que em 1984, as alturas comerciais foram medidas com o hipsômetro de Weiss e, em 2000, estimadas com o uso de varas; o DAP mínimo em 1984 foi de 55 cm para todas as espécies e, em 2000, foi adotado o DAP mínimo de 35 cm. A construção da matriz de transição foi precedida de análise exploratória de dados (AED), em que se utilizou o box plot (caixa-de-bigodes) na detecção de outliers (observações discrepantes) e o gráfico stem-and-leaf (tronco-e-folhas) para filtrar as observações extremas. A análise da estrutura diamétrica mostrou que a evolução do DAP, observada no período 1984-2000, apresentou comportamento diferenciado por espécie, embora mantendo a forma básica da distribuição típica de cada espécie, enquanto a projeção da estrutura diamétrica para 2016, usando matriz de transição, manteve-se com a tendência esperada, com base nas taxas de crescimento expressas pelas raízes latentes da matriz de transição o que demonstra estar compatível com o perfil da estrutura diamétrica observada em 2000.

ABSTRACT This research was originated from a data base of two 100% inventories accomplished in 1984 and 2000 on a same area of 576 hectares of primary tropical forest, located in the National Forest of Tapajós, Belterra, Pará, Brazil. The objective of this research was to evaluate the evolution of diameter structure of 6 commercial tree species in an Amazonian upland forest for the period from 1984 to 2000, and to project it to the year 2016, by using transition matrix. In the two inventories, circunference at breast height (CBH), in cm, were measured with measuring tape, and in 1984, the commercial heights were measured with the hypsometer of Weiss and, in 2000, estimated with the use of sticks; minimum DBH in 1984 were 55 cm for all species and, in 2000, minimum DBH of 35 cm. The construction of the transition matrix was preceded by an exploratory data analysis (EDA), where the box plot was used for outliers detection and the graph stemand-leaf was used to filter the extreme observations. The analysis of the diametric structure showed that the evolution of DBH observed in the period 1984-2000, presented behavior differentiated by species, although maintaining the basic form of the typical distribution of each species, while the projection of the diametric structure for 2016, using transition matrix remained with the expected tendency, according to the expressed growth rates for the latent roots of the transition matrix, demonstrating to be compatible with the profile of the diametric structure observed in the year 2000.

A presente pesquisa apresenta um método de determinação do diâmetro máximo de corte para florestas tropicais utilizando-se a construção gráfica denominada de "Uplot-Dap". O objetivo da pesquisa foi detectar a existência e locação de um possível diâmetro máximo em função do equilíbrio biológico das espécies em uma floresta clímax, utilizando-se o método gráfico "Uplot-Dap". Para testar o método gráfico foram utilizados 28320 DAP com casca de árvores procedentes de 15 blocos de 96 ha da Floresta Nacional do Tapajós, Belterra, Pará. Os gráficos foram construídos considerando uma amplitude de classe diamétrica de 10 cm adotada como valor de referência. O método "Uplot-Dap" que utiliza técnica de análise visual de dados como forma de interpretação da dispersão dos diâmetros, mostrou-se bastante flexível e essencialmente prático. Através do método foi possível fixar o DAP=95 cm como um indicador do diâmetro máximo de explorabilidade a ser adotado na primeira intervenção como valor de referência nas operações de corte para esse tipo de floresta. Todavia, esse ponto pode variar de floresta para floresta e sua nitidez depende do tipo de floresta e suas condições estruturais. A maior contribuição do método gráfico consistiu em respeitar as propriedades das classes diamétricas em florestas naturais que por razões biológicas ou estágio sucessional, expressem a sua distribuição diamétrica como uma função de eventos raros, nulos ou probabilísticos. A eficiência do método baseia-se na sua capacidade de controlar a variação dos dados de modo que as análises sejam mais consistentes com os fatores físicos e biológicos que caracterizam a dinâmica de florestas naturais.

This research presents a method for determination of the maximum diameter of cut in tropical forests being used the denominated graphic construction of "Uplot-Dap". The main objective consisted on detecting the existence and location of a possible maximum diameter in function of the biological balance of the species in a climax forest. To test the graphic method they were used 28320 DBH (cm) outside bark coming from 15 blocks of 96 hectares is of the National Forest of Tapajós, Belterra, Pará, Brazil. The method that uses technique of visual analysis of data as a way of interpretation of the dispersion of the diameters, was shown quite flexible and essentially practical. The graphs were built considering a width of diameter class of 10 cm adopted as reference value. Through this method it was possible to fasten the DBH=95 cm as an indicator of the maximum diameter of exploitability to be adopted in the 1st intervention as reference value in the cut operations for this forest type. Mean while this point can vary from forest to forest and its clearness depends on the forest type and its structural condition. The largest contribution of the graphic method consisted on respecting the properties of the diameter classes in natural forests that for biological reasons or sucessional estate, express its diameter distribution as a function of rare, null or probabilistics events. The efficiency of the method bases on its capacity of controlling the variation of the data so that the analysis are more consistent with the physical and biological factors that characterize the dynamics of natural forests.

Esta pesquisa originou-se de uma base de dados de dois inventários a 100%, realizados em 1984 e 2000 sobre uma mesma área de 576 ha de floresta tropical primária, localizada na Floresta Nacional do Tapajós, Belterra, Pará. O objetivo da pesquisa foi utilizar a análise exploratória de dados e a regressão robusta para modelar o crescimento em diâmetro e área basal. Nos dois inventários as circunferências à altura do peito (CAP) foram medidas com fitamétrica, enquanto as alturas comerciais em 1984 foram medidas com o hipsômetro de Weiss e em 2000, estimadas com o uso de varas; o DAP mínimo em 1984 foi de 55 cm para todas as espécies e em 2000 foi adotado o DAP mínimo de 35 cm. As análises estatísticas foram precedidas de análise exploratória de dados (AED), em que foram utilizados o box plot (caixa-de-bigodes) na detecção de outliers (observações discrepantes) e o gráfico stem-and-leaf (tronco-e-folhas) para filtrar as observações extremas. Utilizou-se a regressão robusta para ajustar os modelos na presença de outliers. A pesquisa mostrou que, apesar das variações intra e interespecíficas, as seis espécies, em conjunto, apresentaram taxas de crescimento medianas observadas e esperadas em diâmetro e área basal de 4,56 e 4,28 mm/ano e 13,00 e 13,09 cm²/ha/ano, respectivamente. A pesquisa também mostrou que o uso da análise exploratória de dados e da regressão robusta viabilizou a análise e a determinação dos incrementos periódicos em diâmetro e área basal em bases consistentes. A metodologia empregada no caso específico dos dados disponíveis e tipos de variáveis mostrou ser mais eficiente com o uso de regressão robusta pelo método Least Trimmed Square do que pelo método dos mínimos quadrados ordinários.

This research originated from a data base of two forest inventories at 100%, carried out in 1984 and 2000 on an area of 576 hectares of an upland primary forest, located in the National Forest of Tapajós, in Belterra, Pará, Brazil. The objective of the research was to use exploratory data analysis and robust regression for modeling diameter and basal area growths. In the two inventories, circumference breast height (CBH)-cm, was measured with a common tape; the commercial heights were measured with a Weise hypsometer in 1984 and, estimated with the use of sticks in 2000. The minimum DBH was 55 cm in 1984 and 35 cm in 2000, for all species. The statistical analyses were preceded by exploratory data analysis (EDA), where the box plot was used for outliers detection, and the stem-and-leaf graph to filter the extreme observations. Robust regression was used to adjust the models in the outliers presence. This research showed that, in spite of the intra and inter specific variations the six species together presented an observed and expected growth rate in diameter and basal area of 4,56 and 4.28 mm/year and 13.00 and 13.09 cm²/ha/year, respectively. It was also shown that the use of exploratory data analysis and robust regression made possible the analysis and determination of periodic increments in diameter and basal area in a consistent way. The methodology used for the available data and variable types was found to be more efficient when using robust regression for the method Least Trimmed Square than for the ordinary minimum square method.

ABSTRACT This research originated from a base of data of 2 forest inventories at 100% carried out in 1984 and 2000 of a same area of 576 hectares of primary tropical forest, located in the National Forest of Tapajós (FLONA TAPAJÓS), Belterra, Pará, Brazil. The objective was to evaluate the levels of errors in obtaining the tree location (xi, yi ) and diameter at breast height (DBH)-cm, basing on the commercial inventories at 100% accomplished in the two ocasions. Circumference at breast height (CBH)-cm, were measured with metric tape in the two inventories. The commercial heights in 1984, were measured with the hipsometer of Weise and, in 2000, estimated visually with the use of sticks; minimum DBH in 1984 were of 55cm for all the species and, in 2000, minimum DBH of 35cm, was adopted. The global medium error of measurement of DBH (cm) for the 6 analyzed species ranged from 2 to 5%, and in terms of diametric class it varied from 8 to 17%. This research showed also that the global level of the average error of estimated of the distance until 5 meters was approximately 14%, being that 41% of the error was refered to distances that ranged from 5 to 10 meters, and that about 60% of the error concentrated in the distance over 10 meters. The evaluation of the average error of estimated of the coordinates (xi, yi ) showed that the used method in 1984 and the adopted method by TREVISO in 2000, produced considered satisfactory result for the planning of the forest management.

RESUMO Esta pesquisa originou-se de uma base de dados de dois inventários a 100% realizados em 1984 e 2000, sobre uma mesma área de 576 ha de floresta tropical primária, localizada na Floresta Nacional do Tapajós (FLONA TAPAJÓS), Belterra, Pará. O objetivo foi avaliar os níveis de erros na obtenção de variáveis de locaçã (xi, yi) e diâmetro à altura do peito (DAP), com base nos inventários comerciais a 100% realizados em 1984 e 2000 na FLONA TAPAJÓS. Nos dois inventários, as circunferência à altura do peito (CAP) foram medidas com fita métrica, sendo que as alturas comerciais em 1984, foram medidas com o hipsômetro de Weise e, em 2000, estimadas com o uso de varas, o DAP mínimo em 1984 foi de 55cm para todas as espécies e, em 2000, foi adotado o DAP mínimo de 35cm. O erro médio global de medição do DAP (cm) para as 6 espécies analisadas variou de 2 a 5% e em termos de classe diamétrica variou de 8 a 17%. A pesquisa também mostrou que o nível global do erro médio de estimativa da distância até 5 metros foi de aproximadamente 14%, sendo que 41% do erro foi atribuído a distâncias que variaram de 5 a 10 metros e que cerca de 60% do erro se concentrou na distância acima de 10 1 metros. A avaliação do erro médio de estimativa das coordenadas (xi, yi ) mostrou que o método utilizado em 1984 e o método atualmente adotado pela TREVISO na FLONA TAPAJÓS produziram resultados considerados satisfatórios para o planejamento do manejo florestal.