ABSTRACT Introduction. Adolescence is a period of biopsychosocial development that goes from 10 to 19 years old. Pregnancy between these ages is a concern for public health due to everything it entails. Objetive. to know the frequency of teenage pregnant women treated in the maternity service of the Pedro Juan Caballero Regional Hospital in the period from December 2021 to November 2022. Material and Method. Descriptive, retrospective cross-sectional, convenience sampling of adolescents treated in the Gynecology service of the Pedro Juan Caballero Regional Hospital in the period December 2021 to November 2022. Results. 20% of the total pregnant women attended were adolescents, 26% of the adolescents were 19 years old, marital status, common-law union 74.5%. 38.2% had at least 5 prenatal checkups. In the Obstetric Gynecological History, 81% were nulliparous. The weight of the 317 children was 2501 to 4000 grams in 83% and in the APGAR score 98.7% had a score of 7-10; 82% were born between 37-42 weeks and 50.3% were boys. The most common route of delivery was vaginal with 73% and cephalic presentation in 97%. Conclusion. The frequency of pregnant adolescents represents a fifth of the total pregnant women attended, more than two thirds were born with adequate weight, mostly an APGAR of 7-10 at 5 minutes and the route by which they were mostly born was vaginal, in cephalic presentation.

RESUMEN Introducción. La adolescencia es un periodo de desarrollo biopsicosocial que va desde los 10 a 19 años, el embarazo entre estas edades supone una preocupación para la salud pública por todo lo que conlleva. Objetivo. Conocer la frecuencia y características clínico-epidemiológicas de gestantes adolescentes atendidas en el servicio de maternidad del Hospital Regional de Pedro Juan Caballero entre diciembre del 2021 a noviembre del 2022 Materiales y Método. Estudio descriptivo, retrospectivo de corte transversal, muestreo por conveniencia de adolescentes atendidas en el servicio de ginecología del Hospital Regional de Pedro Juan Caballero en el periodo diciembre 2021 a noviembre del 2022. Resultados. De 1615 puérperas, el 20% (n=317) fueron adolescentes, 26% de ellas tenían 19 años, 78,5% en unión libre, 38,2% tenía por lo menos 5 controles prenatales. En los antecedentes gineco obstétricos el 81% eran nulíparas. El peso de los 317 niños fue 2501 a 4000 gramos en un 83% y en puntaje APGAR 98,7% presentó un puntaje de 7-10; 82% nació entre 37-42 semanas y 50,3% fueron varones. La vía de parto más común fue la vaginal con 73% y de presentación cefálica en un 97%. Conclusión. La frecuencia de gestantes adolescentes representa una quinta parte del total de gestantes atendidas, más de dos tercios nacieron con peso adecuado, en su mayoría un APGAR de 7-10 a los 5 minutos y la vía por la cual nacieron en su mayoría fue la vaginal, en presentación cefálica.

Abstract Fluorspar (CaF2) is the most used flux in hot metal desulfurizing mixtures. However, its use can cause refractory wear and environmental contamination, prompting research efforts to develop alternative desulfurizing mixtures. This study aims to investigate the replacement desulfurizing mixtures containing fluorspar by other desulfurizing mixtures containing a new flux developed without fluorspar named MIX. The influence of varying the mass of these desulfurizing mixtures, temperature, and stirring of the system on the efficiency of hot metal desulfurization was also studied. The desulfurization experiments were carried out in an electric resistance furnace, at a temperature of 1370°C. Hot metal samples were taken to measure the change in sulfur content in the experiments. FactSage 8.0 software, was used to determine the phases present in the desulfurizing mixtures, and these phases were correlated with the hot metal desulfurization efficiency. The efficiency of the desulfurizing mixtures was also correlated with the Desulfurization Factor. The results showed that desulfurizing mixtures containing fiuorspar are the most efficient mixtures. However, fluorspar-free desulfurizing mixtures containing MIX can achieve similar efficiencies with increases in mass, temperature, and system stirring. The results also showed that the most efficient desulfurizing mixtures are those with higher percentages of solid CaO and lower percentages of the solid phases 3CaO.SiO2 and CaS and, consequently, a higher Desulfurization Factor.

Abstract The objective of the present research was to analyze and compare the programs of study of speech-language pathology in both countries in order to present an initial scenario for future professional standardization in the region. In both Chile and Brazil, the program of Speech-Language Pathology has grown and developed in different universities, with unified curricular guidelines in Brazil. This research is of a quantitative observational type and its sample was constituted by the programs of study of the Federal Universities in Brazil and State Universities in Chile published in the institutional websites corresponding to the year 2020. The data were transcribed and presented using descriptive statistics. A total of 13 federal universities were found in Brazil and 11 state universities in Chile. The admission mode in both countries is through unified tests. The duration of the courses is 8 and 10 semesters in Brazil and 10 semesters in Chile. There is a predominance of subjects in the area of audiology, followed by the areas of language, voice and orofacial motricity in both countries. There is a greater number of research subjects in the Brazilian courses, practical subjects begin early in both countries. Similarities were observed in their proposals with respect to disciplinary areas. Future research should compare the profile of those trained in both countries to verify whether what was seen in the curricular matrices is reflected in the direction of their professional work.

Resumen La presente investigación tuvo como objetivo analizar y comparar los programas de estudio de fonoaudiología en ambos países con la finalidad de presentar un escenario inicial para futuras estandarizaciones profesionales en la región. Tanto en Chile como en Brasil la carrera de fonoaudiología ha crecido y se ha desarrollado en diferentes casas de estudios, con directrices curriculares unificadas en Brasil. Esta investigación es de tipo observacional cuantitativa y su muestra fue constituida por los programas de estudio de las Universidades federales en Brasil y estatales en Chile publicados en los portales institucionales correspondientes al año 2020. Los datos fueron transcritos y presentados mediante la estadística descriptiva. Se encontraron 13 universidades federales en Brasil y 11 estatales en Chile. El modo de ingreso en ambos países es mediante pruebas unificadas. La duración de los cursos es de 8 y 10 semestres en Brasil y 10 semestres en Chile. Hay una predominancia de asignaturas en el área de audiología, seguida de las áreas de lenguaje, voz y motricidad orofacial en ambos países. Existe un mayor número de asignaturas de investigación en los cursos de Brasil, las asignaturas de carácter práctico se inician tempranamente en ambos países. Se apreciaron similitudes en sus propuestas con respecto a las áreas disciplinares. Las investigaciones futuras deben comparar el perfil de quienes se formaron en ambos países para verificar si lo visto en las matrices curriculares se refleja en la dirección de sus labores profesionales.

ABSTRACT Purpose: Sling as a therapeutic option for male stress urinary incontinence (SUI) has been reviewed in the last two decades, as it is a relatively simpliest surgery compared to artificial urinary sphincter and has the ability to modulate urethral compression. This study aims to evaluate the efficacy, rate of complications, quality of life and the effects on bladder emptying of the Argus T® compressive and ajustable sling in moderate and severe male SUI treatment. Materials and Methods: Men eligible for stress urinary incontinence treatment after radical prostatectomy were recruited and prospectively evaluated, from March 2010 to November 2016. It was selected outpatient men with moderate and severe SUI, after 12 months of radical prostatectomy, who have failed conservative treatment. All patients had a complete clinical and urodynamic pre and post treatment evaluation, by means of clinical history, physical examination, urine culture, 1-hour pad test and ICIq-SF questionnaire. The UDS was performed after 12, 18 and 24 months postoperatively. Results: Thirty-seven men underwent sling surgery, 19 patients (51.4%) with moderate and 18 (48.6%) with severe SUI. The minimum follow-up time was 5 years. Overall, we had a success rate of 56.7% at 60 months follow-up. After surgery, we did not observe significant changes in the urodynamic parameters evaluated during the follow-up. No patient had urodynamic bladder outlet obstruction (BOO) after sling implantation. Readjustment of the Argus T® sling was performed in 16 (41%) of the patients and 51% of the patients reported some adverse event. Conclusion: We demonstrate a long-term efficacy and safety of Sling Argus T® as an alternative to moderate and severe male SUI treatment. Furthermore, in our study bulbar urethra compression does not lead to bladder outlet obstruction.

ABSTRACT The original aesthetic form of graffiti and pixação – image/inscription/signature – is significantly dependent on its performative imperatives on the territory – to dribble and overcome the city’s surveillance and discipline devices. Graffiti/pixação recognition process in traditional museums and galleries, via aesthetic transliteration strategies, absorbs the dual aspect of the language, which takes place not only in the graffiti design – the image – but also in the development of the graffiti action – the performance. In this sense, urban art exhibitions elaborate curatorship projects that restore to images their agency on the territory, even if displayed in the institutional shelter, making graffiti not an alternative genre of painting, but an aesthetic transit between contemporary languages.

RESUMEN La forma estética originaria del graffiti y la pintada – dibujo/inscripción/firma – está estrechamente ligada a sus imperativos performativos en el territorio – esquivando y superando los dispositivos de vigilancia y disciplina de la ciudad. El proceso de reconocimiento del graffiti y la pintada en museos y galerías tradicionales, a través de estrategias de transliteración estética, absorbe este doble registro del lenguaje, que se materializa no solo en el trazo efectivamente grafitado – la imagen – sino también en el desarrollo de la acción de hacer graffiti – la performance. En este sentido, las exposiciones de arte urbano elaboran proyectos curatoriales que restituyen a las imágenes, aunque estén expuestas en el refugio institucional, su naturaleza de agente en el territorio, convirtiendo al graffiti no en un género alternativo de pintura, sino en un tránsito estético entre lenguajes contemporáneos.

RESUMO A forma estética originária do grafite e pixação – desenho/inscrição/assinatura – é sensivelmente tributária de seus imperativos performáticos sobre o território – driblar e superar os dispositivos de vigilância e disciplina da cidade. O processo de reconhecimento do grafite e da pixação nos museus e galerias tradicionais, via estratégias de transliteração estética, absorve esse duplo registro da linguagem, que se realiza não apenas no traço efetivamente grafitado – a imagem –, mas inclusive no desenvolvimento da ação de grafitar – a performance. Nesse sentido, as exposições de arte urbana elaboram projetos de curadoria que restituem às imagens, ainda que expostas no abrigo institucional, sua natureza agencial sobre o território, fazendo do grafite não um gênero alternativo de pintura, mas trânsito estético entre linguagens contemporâneas.

ABSTRACT Purpose: To compare ocular surface parameters in rosacea patients with those of controls. Methods: Ninety-three participants took part in this cross-sectional, observational, non-interventional study. These consisted of a rosacea group (n=40) and a control group (n=53). We compared objective parameters of the ocular surface, including conjunctival hyperemia, tear film stability and volume, meibomian gland dysfunction, dry eye disease, and ocular surface staining, between the two groups. Results: In the rosacea group, 69.23% were female. The mean age was 47.34 ± 12.62 years old. No statistically significant differences between groups were found in visual acuity (p=0.987), tear film parameters (tear meniscus height (p=0.338), noninvasive tear film rupture time (p=0.228), invasive rupture time (p=0.471), Schirmer’s test scores (p=0.244), conjunctival hyperemia (p=0.106), and fluorescein staining (p=0.489). Significant differences were found in meibography evaluations (p=0.026), mucous layer integrity (p=0.015), and ocular surface symptoms (p<0.0001). Rosacea patients also showed important eyelid differences in glandular expressibility (p<0.001), glandular secretion pattern (p<0.001), and telangiectasia (p<0.001) compared to controls. Conclusion: Meibomian gland dysfunction is frequently associated with dermatological conditions. It can be observed in morphological findings from meibography as well as lipid secretion impairment, leading to evaporative dry eye, ocular surface dysfunction, and inflammation.

RESUMO Objetivo: Avaliar as alterações da superfície ocular em pacientes com Rosácea, e comparar com grupo controle. Métodos: Noventa e três indivíduos foram selecionados para este estudo transversal, observacional e não intervencionista, dividido em dois grupos: rosácea (n=40) e controles (n=53). Foram avaliados parâmetros objetivos da superfície ocular (hiperemia conjuntival, estabilidade e volume do filme lacrimal, disfunção da glândula meibomiana, doença do olho seco, coloração da superfície ocular) e comparado indivíduos saudáveis com pacientes com rosácea. Resultados: 69,23% dos indivíduos com rosácea eram mulheres, com média de idade de 47,34 ± 12,62 anos. Em comparação com controles pareados, não foram evidenciadas diferenças estatisticamente significativas em relação à acuidade visual (p=0,987) e parâmetros do filme lacrimal (altura do menisco lacrimal (p=0,338), tempo de ruptura do filme lacrimal não invasivo (p=0,228), tempo invasivo de ruptura (p=0,471) e teste de Schirmer (p=0,244), bem como hiperemia conjuntival (p=0,106) e coloração com fluoresceína (p=0,489). Associação significativa foi encontrada na avaliação da meibografia (p=0,026), integridade da camada mucosa (p=0,015) e sintomas de superfície ocular (p<0,0001). Pacientes com rosácea também apresentaram alterações importantes na borda palpebral: expressibilidade glandular (p<0,001), padrão de secreção glandular (p<0,001) e telangiectasia (p<0,001). Conclusão: A disfunção da glândula de Meibômio está frequentemente associada a condições dermatológicas e é caracterizada por achados morfológicos na meibografia, bem como comprometimento da secreção lipídica que leva ao olho seco evaporativo e alterações da superfície ocular e inflamação.

Abstract: The document that is published corresponds to an evaluation carried out by the Central Intelligence Agency (CIA), at the beginning of the government of Salvador Allende and the Popular Unity (19701973), regarding the Revolutionary Left Movement (MIR), the main reference of the Chilean extreme left. Said report allows us to have a close perspective of the points of view and background that the CIA held about this revolutionary organization, including its historical trajectory and close relationship with the Cuban government before and during the experience of the Popular Unity.

Resumen: El documento que se publica corresponde a una evaluación realizada por la Agencia Central de Inteligencia (CIA) estadounidense, a comienzos del gobierno de Salvador Allende y la Unidad Popular (1970-1973), relativa al Movimiento de Izquierda Revolucionaria (MIR), principal referente de la extrema izquierda chilena. Dicho informe, nos permite tener una perspectiva cercana de los puntos de vista y antecedentes que mantenía la CIA acerca de esta organización revolucionaria, incluida su trayectoria histórica y estrecha relación con el gobierno cubano antes y durante la experiencia de la Unidad Popular.

Resumen: La atención hospitalaria de los niños con patología crónica compleja (NPCC) está en aumento, aunque se desconoce su prevalencia real en España. Objetivo: analizar los ingresos hospitalarios y el seguimiento en consultas externas e identificar estrategias para mejorar la calidad de la atención al NPCC. Pacientes y Método: estudio analítico, observacional y retrospectivo que incluyó NPCC que ingresaron en Hospitalización Pediátrica en los últimos 5 años, en un hospital terciario sin unidad específica de crónicos complejos. Se recogieron datos clínicos relacionados con su patología de base, atención en consultas e ingresos hospitalarios. Se realizaron estudios multivariantes para describir los factores de riesgo que explican la necesidad de soporte tecnológico, predecir los ingresos prolongados y la frecuentación hospitalaria en consultas. Resultados: Se incluyeron 99 NPCC (55,6% varones) con una edad de 3,9 (2-8) años. Un 41,4% precisó soporte tecnológico en domicilio y se caracterizó por ser el grupo con mayor número de comorbilidades, ingresos y necesidad de atención por mayor número de especialistas (p < 0,01). Los NPCC de mayor edad (p < 0,01), con enfermedad de base digestiva (p < 0,04) y con comorbilidad respiratoria (p < 0,04) presentaron una estancia media más prolongada en sus ingresos. Los pacientes de menor edad, mayor número de ingresos previos, con mayor estancia media en los ingresos y falta de seguimiento por la enfermera de enlace se asociaron a mayor número de consultas anuales (p < 0,05). Conclusiones: Los NPCC requieren un elevado número de consultas anuales y presentan estancias prolongadas en sus ingresos. La creación de consultas monográficas específicas, la atención multidisciplinar y la implicación de la enfermera de enlace son estrategias para mejorar la calidad de atención de los NPCC en hospitales sin unidades específicas.

Abstract: Hospital care of medically complex children (MCC) is increasing, although its real prevalence in Spain is unknown. Objective: to analyze hospital admissions and outpatient follow-up of MCC in order to identify strategies to improve the quality of care of MCC. Patients and Method: An analytical, observational, and retrospective study was carried out. We included MCC who were admitted to Pediatric Hospitalization in the last 5 years, in a tertiary hospital without a specific unit for MCC. Clinical data related to their underlying pathology, outpatient visits, and hospital admissions were collected. A multivariate study was carried out to describe risk factors of the need for technological support and to predict prolonged admissions and the hospital consultation rate. Results: 99 MCC (55.6% males) aged 3.9 (2-8) years were included. 41.4% of MCC required technological support at home and presented the highest number of comorbidities, hospital admissions, and care by different specialists (p < 0.01). Older MCC (p < 0.01) with underlying digestive disease (p < 0.04) and respiratory comorbidity (p < 0.04) presented a longer mean hospital stays. Younger patients with more admissions, longer average stay, and a lack of follow-up by the link nurse were associated with a greater number of annual consultations (p < 0.05). Conclusions: MCC require a high number of annual consultations and have long hospital stays. The creation of specialized consultations for MCC, multidisciplinary care, and the participation of the link nurse are strategies to improve the quality of care for MCC in hospitals without specific MCC units.

Abstract: Introduction: gastrointestinal stromal tumors are the most common mesenchymal tumors, they can occur anywhere in the digestive tract. Objective: to present the experience of 10 years in the Oncology Unit of the General Hospital of Puebla “Dr. Eduardo Vázquez Navarro” in the management of patients diagnosed with Gastrointestinal stromal tumors. Material and methods: longitudinal, retrospective, observational and clinical study carried out in patients with a histopathological diagnosis of Gastrointestinal stromal tumors between the months of January 2012 to December 2022 in the Oncology Unit of the General Hospital of Puebla. Discussion: 24 records of patients with a diagnosis of Gastrointestinal stromal tumors tumor were reviewed. An institutional incidence of 2% was found. The average age at diagnosis was 53 years, with a male predominance. Surgical treatment was performed in 96% of the cases. A 5-year survival of 16% was found. Recurrence occurred in 16% to liver and lung. Conclusions: gastrointestinal stromal tumors have an unpredictable behavior. Surgery in early stages is the curative treatment. Its indolent presentation makes its diagnosis difficult until advanced stages of the disease. Tyrosine kinase inhibitors have improved survival and are a therapeutic option in cases where surgery is not possible.

Resumen: Introducción: los tumores del estroma gastrointestinal son los tumores mesenquimales más comunes y pueden presentarse en cualquier parte del tracto digestivo. Objetivo: exponer la experiencia de 10 años en la Unidad de Oncología del Hospital General de Puebla “Dr. Eduardo Vázquez Navarro” en el manejo de pacientes con diagnóstico de tumores del estroma gastrointestinal. Material y métodos: estudio longitudinal, retrospectivo, observacional y clínico efectuado en pacientes con diagnóstico histopatológico de tumores del estroma gastrointestinal entre los meses de enero de 2012 y diciembre de 2022 en la Unidad de Oncología del Hospital General de Puebla. Discusión: se revisaron 24 expedientes de pacientes con diagnóstico de tumor del estroma gastrointestinal. Se observó una incidencia institucional de 2%. El promedio de edad al momento del diagnóstico fue de 53 años, con predominio masculino. Se realizó tratamiento quirúrgico en 96% de los casos. Se encontró una supervivencia a cinco años de 16% y se presentó recurrencia en 16% en hígado y pulmón. Conclusiones: los tumores del estroma gastrointestinal tienen un comportamiento impredecible. La cirugía en etapas tempranas es el tratamiento curativo. Su presentación indolente dificulta su diagnóstico hasta etapas avanzadas de la enfermedad. Los inhibidores de tirosina cinasa han mejorado la supervivencia y son una opción terapéutica en casos en los que no es posible realizar la cirugía.

ABSTRACT Decomposition processes and mineralization are essential to determine the time to deploy and manage species in consortia or rotations. The aim of this article was study the dynamics of biomass decomposition and release of macronutrients of plant residues of Fabacea. The species used were: jack bean (Canavalia ensiformis), pigeon pea (Cajanus cajan), dwarf mucuna (Mucuna deeringiana) and sunn hemp (Crotalaria juncea). The experiment was conducted in the field in a randomized block design, 4 x 5 factorial, four species of green manure and five times (0, 30, 60, 90, and 120 days). In the results, sunn hemp and pigeon pea had lower decomposition and release of C, N, K, and Mg. All species, K and P showed similar half-lives (t1/2). For N, sunn hemp presented the lowest coefficient of mineralization (k), 0.0040 g g-1 dia-1, associated with highest t1/2 (173.3 days), already, jack bean showed the highest k (0.0122 g g-1 dia-1) associated with the lowest t1/2 (56.8 days). In edaphoclimatic conditions, use of the jack bean and the dwarf mucuna is recommended for supply of nutrients in shorter periods of time for subsequent crops. However, sunn hemp and pigeon pea are recommended for greater persistence of mulch on the soil.

Abstract Oil palm (Elaeis guineensis L.) is a crucial crop in Ecuador, considerably affected by black palm weevil Rhynchophorus palmarum L. (Coleoptera: Curculionidae) for several years. Despite its importance, the behavior of the black weevil in Ecuador is not well comprehended presently. Therefore, this study aimed to predict infestation patterns of the black palm weevil in Ecuador using a mathematical model based on monitoring data. Data on the number of insects per trap from a commercial oil palm farm in Quinindé, Ecuador, was collected every two weeks for five years (2016-2020) and analyzed using the Classical Fourier (CF) spectrum and the Dickey-Fuller test to determine seasonality. The trend component of the data dropped from 16.33 in January 2017 to 11.96 in January 2019, with a fluctuation ranging from -0.11 to 2.50 observed for the entire data set. The results obtained after fitting the model ranged from -0.11 to 3.19, with a maximum of 5.30. The augmented Dickey-Fuller (ADF) test for the black weevil time series yielded a result of -5.60 (P<0.01). The partial autocorrelation ranged from -0.35 to 0.1. Based on our model, we projected the occurrence of black palm weevil from 2021 to 2024, with a fluctuation in the number of insects per trap ranging from 12.68 in January 2021 to 13.023 in November 2023. This model can be used to predict future insect occurrences in Ecuador, providing valuable insights into the behavior of the black weevil and using it for effective development control measures for this pest.

Resumen El periodo 1969-1973, en lo que refiere a la campaña electoral que llevó a Salvador Allende a convertirse en presidente de Chile (1970) y al gobierno de la Unidad Popular, son observados como objeto de interés y reflexión para un instrumento revolucionario: la revista Punto Final. Esto, toda vez que en sus páginas es posible observar algunas coordenadas teóricas en torno a cómo se configura un fenómeno revolucionario, específicamente cuando se lo entiende como conectado y entrelazado a otros procesos reivindicatorios en Latinoamérica o porque se recurre de manera diversa a incorporar a una serie de agentes en la narrativa revolucionaria que se construye primero en oposición a la vía pacífica y al apoyo al imperialismo con que se signa el periodo de Eduardo Frei Montalva (19641970), y luego porque se construye como un camino hacia el socialismo que se basa en la construcción de alianzas.

Abstract The period 1969-1973,in what refers to the electoral campaign that led SalvadorAllende to become Chilean president (1970) and his “Popular Unity” government, are observed as an object of interest and reflection for a revolutionary instrument: the Magazine Punto Final. This, since in its pages it is possible to observe some theoretical coordinates around how a revolutionary phenomenon is configured,specifically when it is understood as connected and intertwined with other processes of vindication in Latin America or because it is used in a different way to incorporate a series of agents in the revolutionary narrative that is first constructed in opposition to the peaceful path and support for imperialism with which the period of Eduardo Frei Montalva (1964-1970) is signed,and then because it is constructed as a path towards socialism that it is based on the construction of alliances.

Abstract Background Atrial fibrillation (AF) is an important cause of cardioembolic stroke, and population aging has increased its prevalence. Objective To evaluate the incidence of cardioembolic stroke caused by AF in the city of Joinville, Brazil, as well as previous diagnoses and use of medication. Methods Between 2017 and 2020 we extracted data from the population-based Joinville Stroke Registry. Demographic characteristics, diagnosis of AF, and patterns of medication use were collected, and the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) system was used to classify the etiology. Results There were 3,303 cases of ischemic stroke, 593 of which were cardioembolic, and 360 had AF. Of the patients with AF, 258 (71.6%) had a previous diagnosis of the disease, and 102 (28.3%) were newly diagnosed after the stroke. Among patients with a previously-diagnosed AF, 170 (47.2%) were using anticoagulants, and 88 (24.4%) were using other medications. Conclusion During the analyzed period, ischemic stroke caused by AF was a significant burden on the population of Joinville, and a considerable number of patients had undiagnosed or untreated AF.

Resumo Antecedentes A fibrilação atrial (FA) é uma importante causa de acidente vascular cebebral (AVC) cardioembólico, e o envelhecimento populacional aumentou a sua prevalência. Objetivo Avaliar a incidência de AVC cardioembólico causado por FA em Joinville, além dos diagnósticos prévios e do uso de medicamentos. Métodos Entre 2017 e 2020, foram extraídos dados do registro de base populacional de AVC de Joinville. Características demográficas, diagnóstico de FA e padrões de uso de medicamentos foram coletados, e o sistema Trial of ORG 10172 in Acute Stroke Treatment (TOAST) foi utilizado para classificar a etiologia. Resultados Houve 3.303 casos de AVC isquêmico, sendo 593 cardioembólicos e 360 com FA. Dos pacientes com FA, 258 (71,6%) tinham diagnóstico prévio da doença, e 102 (28,3%) foram recém-diagnosticados após o AVC. Entre os pacientes com FA previamente diagnosticada, 170 (47,2%) estavam em uso de anticoagulante, e 88 (24,4%), em uso de outra medicação. Conclusão Durante o período analisado, o AVC isquêmico causado por FA foi um ônus significativo para a população de Joinville, e um número considerável de pacientes apresentava FA não diagnosticada ou não tratada.

Abstract The zoanthid Palythoa caribaeorum secretes a large quantity of mucus that acts as a substrate for microbial communities. Culturable bacteria associated with P. caribaeorum mucus in northeastern Brazil were evaluated through 16S rRNA gene sequences. Proteobacteria was the dominant group, followed by Actinobacteria and Firmicutes. Vibrio was the most common genus, although other groups with the ability to produce biosurfactants and compounds with antimicrobial activity were also present. The studies of culturable marine bacteria may contribute to the understanding of the associated microbial community, opening new opportunities to explore biotechnological potential of microbiota.