ABSTRACT The methanolic extract from stem bark of Bauhinia monandra, a medicinal plant employed in folk medicine, yielded by column chromatography lup-20(29)-en-3β,24-diol ( 1) and methyl galloate (2) along with β-sitosterol ( 3). These known phytoconstituents are being reported for the first time from this plant and their structures were established by NMR and MS spectral studies and by comparison with their literature data. Furthermore, lup-20(29)-en-3β,24-diol (1 ), a minor constituent, was isolated from this genus for the first time.

This study represents an integrated approach towards understanding the electronic and structural aspects of 2-benzylamino-1,4-naphthalenedione, a representative 2-amino-napfthoquinone. To this end, theoretical calculations performed at the B3PW91/6-31+G(d) level of density functional theory, electrochemical and X-ray structural investigation were employed. Two intramolecular H-bonds and other two intermolecular H-bonds were observed, including non-classical interactions. Cyclic voltammogram (CV) and differential pulse voltammetry (DPV) show two pairs of peaks, being each one a monoelectronic process.

Um novo triterpeno (22beta-hidroxilupeol) foi isolado do extrato em metanol do caule de Moldenhawera nutans (Leguminosae) além de diterpenos derivados do ácido labdenóico de ocorrência comum nesta espécie. A partir do ácido labd-8(17)-en-15-óico foram preparados derivados com atividade in vitro discreta frente à Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella cholerasuis e Vibrio parahaemolyticus.

A new triterpene derivative (22beta-hydroxylupeol) was isolated from the MeOH extract of stems of Moldenhawera nutans (Leguminosae) together with labdenoic acid derivatives of common occurrence in this species. From the labd-8(17)-en-15-oic acid were prepared simple derivatives, which exhibited in vitro weak activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella cholerasuis, and Vibrio parahaemolyticus.