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au:FIGUEIREDO, PAULA DE OLIVEIRA

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AVALIAÇÃO DE COMPOSTOS ORGÂNICOS VOLÁTEIS AROMÁTICOS NA ATMOSFERA EM CAMPOS DOS GOYTACAZES E ITAPERUNA APLICANDO A ANÁLISE MULTIVARIADA DE DADOS
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Vieira, Hellen Gonçalves

; Figueiredo, Ana Paula de Souza

; Souza, Murilo de Oliveira

; Canela, Maria Cristina

Química Nova

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2023, Volume 46 N. 1 Pages 29 - 38

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Volatile Organic Compounds (VOCs) are air pollutants emitted from different sources, mainly by industries and motor vehicles. The evaluation of the emission of these compounds into the atmosphere should be done systematically and with a varied class of compounds. The large number of data generated during the monitoring of these VOCs requires the use of multivariate data tools to interpret the results. In this sense, this work aimed to monitor 10 aromatic VOCs present in the atmosphere of the largest cities in the Norte Fluminense (Campos dos Goytacazes) and Noroeste Fluminense (Itaperuna) regions. The VOCs were actively sampled and analyzed by gas chromatography with mass spectrometry detection after thermal desorption. After treatment of analytical results, it was observed that in both cities there is influence of vehicular emissions. In the city of Itaperuna, due to the relief and lower dispersion of contaminants, there is a higher occurrence of photochemical reactions. The exploratory analysis of the data allowed identifying the variables that were more significant and correlating these variables with the main sources of emission of the compounds. This is the first study of VOCs evaluation in Campos dos Goytacazes and Itaperuna, demonstrating the relevance of this research for understanding the behavior of VOCs in these cities, which have different reliefs and high traffic of cars and trucks in the studied sites.

https://doi.org/10.21577/0100-4042.20170952

Posicionamento Brasileiro sobre Síndrome da Quilomicronemia Familiar – 2023
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Izar, Maria Cristina de Oliveira

; Santos Filho, Raul Dias dos

; Assad, Marcelo Heitor Vieira

; Chagas, Antonio Carlos Palandri

; Toledo Júnior, Alceu de Oliveira

; Nogueira, Ana Cláudia Cavalcante

; Souto, Ana Cristina Carneiro Fernandes

; Lottenberg, Ana Maria

; Chacra, Ana Paula Marte

; Ferreira, Carlos Eduardo dos Santos

; Lourenço, Charles Marques

; Valerio, Cynthia Melissa

; Cintra, Dennys Esper

; Fonseca, Francisco Antonio Helfenstein

; Campana, Gustavo Aguiar

; Bianco, Henrique Tria

; Lima, Josivan Gomes de

; Castelo, Maria Helane Costa Gurgel

; Scartezini, Marileia

; Moretti, Miguel Antonio

; Barreto, Natasha Slhessarenko Fraife

; Maia, Rayana Elias

; Montenegro Junior, Renan Magalhães

; Alves, Renato Jorge

; Figueiredo, Roberta Marcondes Machado

; Fock, Rodrigo Ambrosio

; Martinez, Tânia Leme da Rocha

; Giraldez, Viviane Zorzanelli Rocha

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 4 elocation e20230203

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230203

Relationship of residual feed intake with semen parameters and testicular ultrasound of Nellore bulls
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Borges, Marcelo Sant’Ana

; Silva, Marina de Oliveira

; Fernandes, Luana Gomes

; Rodrigues, Naiara Nantes

; Rossi, Guilherme Fazan

; Freitas-Dell’Aqua, Camila de Paula

; Bonilha, Sarah Figueiredo Martins

; Mercadante, Maria Eugênia Zerlotti

; Monteiro, Fabio Morato

Revista Brasileira de Zootecnia

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2023, Volume 52 elocation e20220041

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate characteristics of the testicular parenchyma and vascular parameters of the pampiniform plexus obtained by ultrasound, semen quality parameters, and sperm freezability in Nellore bulls classified based on residual feed intake (RFI). Twenty-seven bulls (21.82±0.88 months of age) evaluated for feed efficiency were sampled for the study, including 15 with low RFI (−0.592±0.09 kg dry matter/day) and 12 with high RFI (0.792±0.10 kg dry matter/day). In ultrasound and Doppler assessment, the most efficient animals (low RFI) showed higher pulsatility and resistive indexes, as well as a tendency towards greater heterogeneity of the testicular parenchyma (0.625±0.032 vs. 0.508±0.032, 1.012±0.072 vs. 0.802±0.072, and 12.9±0.96 vs. 10.2±0.96, respectively, for low vs. high RFI). However, these animals tended to have lower peak diastolic velocity (5.19±0.50 for low RFI vs. 6.54±0.50 for high RFI). Analysis of fresh semen showed a lower percentage of minor defects in low RFI animals (2.67±1.19%) compared with high RFI animals (8.10±1.19%), without differences in the other parameters in fresh or thawed semen and after thermoresistance testing. Evaluation of flow cytometry parameters showed a higher quality of mitochondrial respiration in semen samples of low RFI animals (22.04±2.50%) compared with high RFI animals (12.29±2.71%). Therefore, although RFI exerts an effect on the Doppler parameters of the pampiniform plexus, it is not sufficient to affect the quality of fresh or thawed semen.

https://doi.org/10.37496/rbz5220220041

Fatores associados à elevada exposição ao comportamento sedentário em pessoas idosas: uma análise com dados da Pesquisa Nacional de Saúde, 2019
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Oliveira-Figueiredo, Danielle Samara Tavares de

; Silva, Matteus Pio Gianotti Pereira Cruz

; Feitosa, Paula Yhasmym de Oliveira

; Miranda, Allana Petrucia Medeiros de

Revista Brasileira de Geriatria e Gerontologia

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2023, Volume 26 elocation e230056

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective To analyze the factors associated with sedentary behavior in older adults. Method A cross-sectional study of data from the 2019 National Health Survey involving 22,728 older Brazilian adults was conducted. The outcome was sedentary behavior and the exposures included sociodemographic characteristics, lifestyle, household characteristics and chronic diseases. Multiple logistic regression was used. with a significance level of 5%. Results The prevalence of sedentary behavior was 32.8% (95%CI: 31.8-33.8) There was a greater chance for the outcome in individuals that were female (OR=1.20; 95%CI: 1.08-1.34); aged 70-79 years (OR= 1.22; 95%CI: 1.09-1.36); aged ≥80 years (OR=1.18; 95% CI: 1.02-1, 36); had no partner (OR= 1.27; 95%CI: 1.14-1.41); were diabetic (OR =1.17; 95%CI: 1.06-1.30), had systemic arterial hypertension (OR =1.34; 95%CI: 1.18-1.51). previous stroke (OR = 1.61; 95%CI: 1.32-1.96), and no place to perform physical activity close to home (OR=1.16; 95%CI: 1.05-1.29). Older adults with low education (OR= 0.71; 95%CI: 0.61-0.82), and that resided in rural areas (OR=0.53; 95%CI: 0.47-0.61) were less likely to be sedentary. Conclusion Individuals that were female, older(ager > 70 years), had diabetes, hypertension, previous stroke, and no place to perform physical activity close to home, were associated with high exposure to sedentary behavior. Living in rural areas and having less education were inversely associated with this risk behavior.

Resumo Objetivo Analisar os fatores associados ao comportamento sedentário em pessoas idosas. Método Estudo transversal, com dados da Pesquisa Nacional de Saúde, 2019 com 22.728 pessoas idosas do Brasil. O desfecho foi o comportamento sedentário e as exposições: características sociodemográficas, estilo de vida, características do domicílio e doenças crônicas. Foi empregada a regressão logística múltipla e um nível de significância de 5%. Resultados A prevalência do comportamento sedentário foi 32,8% (IC95%: 31,8-33,8).Verificou-se maior chance para o desfecho no sexo feminino (OR =1,20; IC 95%: 1,08-1,34), entre as faixas etárias de 70 a 79 anos (OR = 1,22; IC 95%: 1,09-1,36) e 80 anos ou mais (OR=1,18; IC 95%: 1,02-1,36); entre pessoas idosas quem não tem companheiro (OR= 1,27; IC95%: 1,14-1,41); diabéticos (OR =1,17; IC 95%: 1,06-1,30), hipertensos (OR =1,34; IC 95%: 1,18-1,51), naqueles que tiveram Acidente Vascular Cerebral (OR = 1,61; IC 95%: 1,32-1,96) e naqueles que não têm lugar para praticar atividade física próximo do domicilio (OR =1,16; IC95%:1,05-1,29). Pessoas idosas com baixa escolaridade (OR = 0,71; IC 95%: 0,61- 0,82), e residentes em zona rural (OR = 0,53; IC 95%: 0,47-0,61) possuem menores chances de comportamento sedentário. Conclusão Mulheres, maiores faixas etárias (a partir dos 70 anos), pessoas com diabetes, hipertensão e que já tiveram AVE, e que não possuem locais para prática de atividade física próximo à residência foram associados à elevada exposição ao comportamento sedentário. Enquanto, viver em zonas rurais e possuir menor escolaridade apresentaram associação inversa a esse comportamento de risco.

https://doi.org/10.1590/1981-22562023026.230056.pt

Características Edáficas das Áreas de Olival do Nordeste de Portugal: abordagem baseada em cartografia de solos e ocupação do solo
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Santos, Renecleide Viana dos

; Fonseca, Felícia

; Royer, Ana Caroline

; Hernandez, Zulimar

; Baptista, Paula

; Figueiredo, Tomás de

Revista de Ciências Agrárias

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dec 2022, Volume 45 N. 4 Pages 81 - 90

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A oliveira é atualmente a cultura que ocupa a maior superfície agrícola em Portugal e a exploração dos seus frutos reveste-se de grande importância socioeconómica. Existe pouca informação disponível sobre as condições edáficas em áreas cultivadas com olivais no Nordeste de Portugal e como elas exercem influência na distribuição e desenvolvimento da cultura. Dessa forma, este estudo visa contribuir com a atualização da informação existente através da identificação das principais características edafoclimáticas das áreas olivícolas na Região. A informação de base para o estudo incluiu como fontes principais a Carta dos Solos e da Aptidão da Terra do NE Portugal, a Carta de Uso e Ocupação do Solo e a Carta Administrativa Oficial de Portugal. O olival cobre aproximadamente 105 mil ha no NE de Portugal e é a cultura que ocupa a maior área agrícola da Região. Os solos sob olivais são geralmente pouco profundos, pedregosos, ácidos e pobres em matéria orgânica, grande parte situando-se em terrenos declivosos. As oliveiras estão bem-adaptadas aos condicionalismos edafoclimáticos regionais, mas é necessário implementar práticas alternativas que promovam uma melhor gestão dos pomares, para o que é importante aprofundar o conhecimento dos solos das áreas de olival.

Abstract The olive tree is currently the crop that occupies the largest agricultural area in Portugal and the exploitation of its fruits is of great socio-economic importance. There is little information available on edaphic conditions in areas cultivated with olive groves in Northeast Portugal and how they influence the distribution and development of the crop. Thus, this study aims to contribute to the updating of existing information through the identification of the main soil and climate characteristics of the olive growing areas in the Region. The basic information for the study included as main sources the Land Aptitude Charter of NE Portugal, the Land Use and Occupation Charter and the Official Administrative Charter of Portugal. The olive grove covers approximately 105 thousand ha in NE Portugal and is the crop that occupies the largest agricultural area in the Region. Soils under olive groves are generally shallow, stony, acidic and poor in organic matter, most of which are located on sloping terrain. Olive trees are well adapted to regional soil and climate conditions, but it is necessary to implement alternative practices that promote better management of orchards, for which it is important to deepen knowledge of the soils of olive groves.

https://doi.org/10.19084/rca.28386

Otoneurological assessment and quality of life of individuals with complaints of dizziness and temporomandibular disorders: a case-control study
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Honorato, Mônica Claudino Medeiros

; Tavares, Luiz Felipe

; Bedaque, Henrique de Paula

; Mantello, Erika Barioni

; Almeida, Erika Oliveira de

; Ribeiro, Karyna Myrelly Oliveira Bezerra de Figueiredo

; Ferreira, Lidiane Maria de Brito Macedo

Brazilian Journal of Otorhinolaryngology

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dec 2022, Volume 88 Pages 185 - 191

Abstract: En | Text: En | PDF: En

Abstract Objectives: To evaluate the impact of temporomandibular disorders on the quality of life of patients with dizziness. Methods: An observational, case-control study evaluated 60 individuals with dizziness (20 cases and 40 controls), who were matched for gender and age. The individuals underwent to anamnesis, overall physical and otoneurological examination, tonal and vocal audiometry and impedanciometry, video head impulse test and the dizziness handicap inventory questionnaire. Results: The otoscopy was normal for all patients. There was an association between the presence of temporomandibular disorders and aural fullness (p<0.01) and otalgia (p<0.01). Audiometry was normal in 90% of the patients in the case group, with a significant association between temporomandibular disorders and normal audiometry (p<0.01). The video head impulse test findings were normal in 66% of the patients in the case group and 45% of the control group, and there was no association between having temporomandibular disorders and vestibular alterations at the video head impulse test (p = 0.12). There were significant differences in total dizziness handicap inventory and in the functional and emotional domains (p<0.01), with higher scores in the control group. Conclusion: Aural fullness and otalgia symptoms are associated with temporomandibular disorders in patients with dizziness, and there is an association between normal complementary audiological tests and temporomandibular disorders. Vestibular alterations are not associated with temporomandibular disorders. However, patients with dizziness and without temporomandibular disorders showed greater quality of life impairment. Level of evidence: 3. Original case-control study.

https://doi.org/10.1016/j.bjorl.2022.04.005

Consensus of the Brazilian Headache Society (SBCe) for prophylactic treatment of episodic migraine: part II
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Santos, Paulo Sergio Faro

; Melhado, Eliana Meire

; Kaup, Alexandre Ottoni

; Costa, Aline Turbino Neves Martins da

; Roesler, Célia Aparecida de Paula

; Piovesan, Élcio Juliato

; Sarmento, Elder Machado

; Theotonio, Giselle Oliveira Martins

; Campos, Henrique Carneiro de

; Fortini, Ida

; Souza, Jano Alves de

; Maciel Júnior, Jayme Antunes

; Segundo, João Batista Alves

; Carvalho, João José Freitas de

; Speziali, José Geraldo

; Calia, Leandro Cortoni

; Barea, Liselotte Menke

; Queiroz, Luiz Paulo

; Souza, Marcio Nattan Portes

; Figueiredo, Marcos Ravi Cerqueira Ferreira

; Costa, Maria Eduarda Nobre de Magalhães

; Peres, Mário Fernando Prieto

; Jurno, Mauro Eduardo

; Peixoto, Patrícia Machado

; Kowacs, Pedro André

; Rocha Filho, Pedro Augusto Sampaio

; Moreira Filho, Pedro Ferreira

; Silva Neto, Raimundo Pereira

; Fragoso, Yara Dadalti

Arquivos de Neuro-Psiquiatria

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sep 2022, Volume 80 N. 9 Pages 953 - 969

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Migraine affects 1 billion people worldwide and > 30 million Brazilians; besides, it is an underdiagnosed and undertreated disorder. Objective The need to disseminate knowledge about the prophylactic treatment of migraine is known, so the Brazilian Headache Society (SBCe, in the Portuguese acronym) appointed a committee of authors with the objective of establishing a consensus with recommendations on the prophylactic treatment of episodic migraine based on articles from the world literature as well as from personal experience. Methods Meetings were held entirely online, with the participation of 12 groups that reviewed and wrote about the pharmacological categories of drugs and, at the end, met to read and finish the document. The drug classes studied in part II of this Consensus were: antihypertensives, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, calcium channel blockers, other drugs, and rational polytherapy. Results From this list of drugs, only candesartan has been established as effective in controlling episodic migraine. Flunarizine, venlafaxine, duloxetine, and pizotifen were defined as likely to be effective, while lisinopril, enalapril, escitalopram, fluvoxamine, quetiapine, atorvastatin, simvastatin, cyproheptadine, and melatonin were possibly effective in prophylaxis of the disease. Conclusions Despite an effort by the scientific community to find really effective drugs in the treatment of migraine, given the large number of drugs tested for this purpose, we still have few therapeutic options.

Resumo Antecedentes Migrânea afeta um bilhão de pessoas em todo o mundo e mais de 30 milhões de brasileiros; além disso, é um distúrbio subdiagnosticado e subtratado. Objetivo Sabe-se sobre a necessidade de difundir o conhecimento sobre o tratamento profilático da migrânea; por isso, a Sociedade Brasileira de Cefaleias (SBCe) nomeou um comitê de autores com o objetivo de estabelecer um consenso com recomendações sobre o tratamento profilático da migrânea episódica com base em artigos da literatura mundial, assim como da experiência pessoal. Métodos As reuniões foram realizadas inteiramente online, com a participação de 12 grupos que revisaram e escreveram sobre as categorias farmacológicas dos medicamentos e, ao final, reuniram-se para a leitura e conclusão do documento. As classes de medicamentos estudadas na parte II deste Consenso foram: anti-hipertensivos, inibidores seletivos de recaptação de serotonina, inibidores de recaptação de serotonina e noradrenalina, bloqueadores dos canais de cálcio, outros medicamentos e politerapia racional. Resultados Desta lista de medicamentos, apenas o candesartan foi estabelecido como eficaz no controle da migrânea episódica. Flunarizina, venlafaxina, duloxetina e pizotifeno foram definidos como provavelmente eficazes, enquanto lisinopril, enalapril, escitalopram, fluvoxamina, quetiapina, atorvastatina, sinvastatina, ciproheptadina e melatonina foram possivelmente eficazes na profilaxia da doença. Conclusões Apesar do esforço da comunidade científica em encontrarmedicamentos realmente eficazes no tratamento da migrânea, dado o grande número de medicamentos testados para este fim, ainda dispomos de poucas opções terapêuticas.

https://doi.org/10.1055/s-0042-1755320

Consensus of the Brazilian Headache Society (SBCe) for the Prophylactic Treatment of Episodic Migraine: part I
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Melhado, Eliana Meire

; Santos, Paulo Sergio Faro

; Kaup, Alexandre Ottoni

; Costa, Aline Turbino Neves Martins da

; Roesler, Célia Aparecida de Paula

; Piovesan, Élcio Juliato

; Sarmento, Elder Machado

; Theotonio, Giselle Oliveira Martins

; Campos, Henrique Carneiro de

; Fortini, Ida

; Souza, Jano Alves de

; Maciel Júnior, Jayme Antunes

; Segundo, João Batista Alves

; Carvalho, João José Freitas de

; Speziali, José Geraldo

; Calia, Leandro Cortoni

; Barea, Liselotte Menke

; Queiroz, Luiz Paulo

; Souza, Marcio Nattan Portes

; Figueiredo, Marcos Ravi Cerqueira Ferreira

; Costa, Maria Eduarda Nobre de Magalhães

; Peres, Mário Fernando Prieto

; Jurno, Mauro Eduardo

; Peixoto, Patrícia Machado

; Kowacs, Pedro André

; Rocha-Filho, Pedro Augusto Sampaio

; Moreira Filho, Pedro Ferreira

; Silva-Neto, Raimundo Pereira

; Fragoso, Yara Dadalti

Arquivos de Neuro-Psiquiatria

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aug 2022, Volume 80 N. 8 Pages 845 - 861

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The Brazilian Headache Society (Sociedade Brasileira de Cefaleia, SBCe, in Portuguese) nominated a Committee of Authors with the aim of establishing a consensus with recommendations regarding prophylactic treatment for episodic migraine based on articles published in the worldwide literature, as well as personal experience. Migraine affects 1 billion people around the world and more than 30 million Brazilians. In addition, it is an underdiagnosed and undertreated disorder. It is well known within the medical community of neurologists, and especially among headache specialists, that there is a need to disseminate knowledge about prophylactic treatment for migraine. For this purpose, together with the need for drug updates and to expand knowledge of the disease itself (frequency, intensity, duration, impact and perhaps the progression of migraine), this Consensus was developed, following a full online methodology, by 12 groups who reviewed and wrote about the pharmacological categories of the drugs used and, at the end of the process, met to read and establish conclusions for this document. The drug classes studied were: anticonvulsants, tricyclic antidepressants, monoclonal anti-calcitonin gene-related peptide (anti-CGRP) antibodies, beta-blockers, antihypertensives, calcium channel inhibitors, other antidepressants (selective serotonin reuptake inhibitors, SSRIs, and dual-action antidepressants), other drugs, and polytherapy. Hormonal treatment and anti-inflammatories and triptans in minimum prophylaxis schemes (miniprophylaxis) will be covered in a specific chapter. The drug classes studied for part I of the Consensus were: anticonvulsants, tricyclic antidepressants, monoclonal anti-CGRP antibodies, and beta-blockers.

Resumo A Sociedade Brasileira de Cefaleia (SBCe) nomeou um Comitê de Autores com o objetivo de estabelecer um consenso com recomendações sobre o tratamento profilático da enxaqueca episódica com base em artigos da literatura mundial e da experiência pessoal. A enxaqueca é um distúrbio subdiagnosticado e subtratado que acomete um bilhão de pessoas no mundo e mais de 30 milhões de brasileiros. É conhecido na comunidade médica de neurologistas e, sobretudo, dos especialistas em cefaleia, a necessidade de se divulgar o conhecimento sobre o tratamento profilático da enxaqueca. Com esta finalidade, aliada às necessidades de atualizações de drogas e de se aumentar o conhecimento sobre a doença em si (frequência, intensidade, duração, impacto e talvez a progressão da enxaqueca), foi elaborado este Consenso, com metodologia totalmente on-line, por 12 grupos que revisaram e escreveram sobre as categorias farmacológicas das drogas e, ao final, reuniram-se para a leitura e conclusão do documento. As classes de drogas estudadas para este Consenso foram: anticonvulsivantes, antidepressivos tricíclicos, anticorpos monoclonais do antipeptídeo relacionado ao gene da calcitonina (peptídeo relacionado ao gene da calcitonina — anti-CGRP), betabloqueadores, anti-hipertensivos, inibidores dos canais de cálcio, outros antidepressivos (inibidores seletivos de recaptação de serotonina, ISRSs, e antidepressivos de ação dual), outras drogas, e politerapia. O tratamento hormonal, bem como anti-inflamatórios e triptanas em esquema de profilaxia mínima (miniprofilaxia), será abordado em um capítulo próprio. As classes de drogas estudadas na parte I do Consenso foram: anticonvulsivantes, antidepressivos tricíclicos, anticorpos monoclonais anti-CGRP, e betabloqueadores.

https://doi.org/10.1055/s-0042-1756441

Performance and reference intervals of thrombin generation test: results from the Brazilian longitudinal study of adult health (ELSA-Brasil). A cross-sectional study
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Rios, Danyelle Romana Alves

; Barreto, Sandhi Maria

; Ferreira, Letícia Gonçalves Resende

; Batista, Thaís Resende

; Silva, Ana Paula Ferreira

; de Oliveira Júnior, Wander Valadares

; Maluf, Chams Bicalho

; Carvalho, Maria das Graças

; Figueiredo, Roberta Carvalho

Sao Paulo Medical Journal

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jun 2022, Volume 140 N. 3 Pages 474 - 485

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The thrombin generation test (TGT) has shown promise for investigation of hemorrhagic and thrombotic diseases. However, despite its potential, it still needs standardization. Moreover, few studies have established reference values for TGT parameters. In Brazil, these values have not yet been established. OBJECTIVE: To determine TGT performance and reference intervals for TGT parameters in healthy individuals. DESIGN AND SETTING: Cross-sectional study conducted among participants in the Brazilian Longitudinal Study of Adult Health (Estudo Longitudinal de Saúde do Adulto, ELSA-Brasil). METHODS: The reference sample consisted of 620 healthy individuals. The calibrated automated thrombogram (CAT) method, under low and high tissue factor (TF) conditions, was used to assess thrombin generation. Test performance was analyzed using intra and interassay coefficients of variation (CV) and reference intervals were calculated using the nonparametric method proposed by the International Federation of Clinical Chemistry and the Clinical and Laboratory Standards Institute. RESULTS: The intraassay CV ranged from 1.4% to 2.2% and the interassay CV, 6.8% to 14.7%. The reference intervals for TGT parameters under low and high TF conditions were, respectively: lagtime: 3.0-10.3 and 1.4-3.7 min; endogenous thrombin potential (ETP): 1134.6-2517.9 and 1413.6-2658.0 nM.min; normalized ETP: 0.6-1.3 and 0.7-1.4; peak: 103.2-397.7 and 256.4-479.0 nM; normalized peak: 0.3-1.3 and 0.7-1.2; and time-to-peak: 5.6-16.0 and 3.4-6.7 min. These parameters were categorized relative to sex. Conclusion: TGT performance was adequate and the proposed reference intervals were similar to those of other studies. Our findings may be useful for consolidating the TGT, through contributing to its standardization and validation.

https://doi.org/10.1590/1516-3180.2021.0425.r1.07102021

10.

Mortality due to hepatocellular carcinoma associated with hepatitis B and C viruses in the state of São Paulo, Brazil
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Cavalcante, Débora Ferro

; Garcia, Érica Marvila

; Farias, Norma Suely de Oliveira

; Koizumi, Inês Kazue

; Figueiredo, Gerusa Maria

; Sato, Ana Paula Sayuri

Revista Brasileira de Epidemiologia

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2022, Volume 25 elocation e220004

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivos: Este estudo tem como objetivo descrever e analisar a distribuição temporal e espacial dos óbitos por carcinoma hepatocelular associados às hepatites virais B e C no estado de São Paulo. Métodos: Estudo ecológico dos óbitos por carcinoma hepatocelular associados a hepatites virais B e hepatites virais C no estado de São Paulo, de 2009 a 2017, com dados do Sistema de Informação sobre Mortalidade. A tendência temporal foi analisada por regressão linear, com método de Prais-Winsten. Os óbitos foram descritos segundo as características sociodemográficas, por meio de frequências absolutas e relativas, e foram espacialmente distribuídos segundo departamento regional de saúde. Resultados: Dos óbitos por carcinoma hepatocelular, 26,3% foram associados a hepatites virais B ou hepatites virais C. Observou-se maior proporção de óbitos por carcinoma hepatocelular associado a hepatites virais C (22,2%) quando comparada àquela associada a hepatites virais B (3,9%). A taxa de mortalidade por carcinoma hepatocelular associado a hepatites virais B apresentou tendência de queda, no entanto a taxa de mortalidade por carcinoma hepatocelular associado a hepatites virais C apresentou tendência estacionária. Predominaram óbitos de pacientes do sexo masculino, de cor branca, de 50–59 anos e com oito a 11 anos de estudo. A análise espacial revelou distribuição heterogênea dos óbitos no estado de São Paulo. Conclusão: A tendência de queda nas taxas de mortalidade por carcinoma hepatocelular associado a hepatites virais B revela um importante avanço no controle do agravo. Entretanto, a taxa de mortalidade por carcinoma hepatocelular associado a hepatites virais C vem-se mantendo estável ao longo do período estudado. A distribuição espacial dos óbitos pode contribuir para levantar hipóteses com vistas ao conhecimento mais aprofundado desses agravos nas regiões.

ABSTRACT: Objective: This study aimed to describe and analyze the temporal and spatial distribution of deaths due to hepatocellular carcinoma (HCC) associated with hepatitis B (HBV) and C viruses (HCV) in the state of São Paulo. Methods: This is an ecological study of HCC deaths associated with HBV and HCV in the state of São Paulo, from 2009 to 2017, with data from the Mortality Information System (SIM). The temporal trend was analyzed by linear regression with Prais–Winsten estimation. Deaths were described according to sociodemographic characteristics by means of absolute and relative frequencies and were spatially distributed according to the regional health department. Results: It is found that 26.3% of deaths due to HCC were associated with HBV or HCV. A higher proportion of deaths due to HCC associated with HCV was observed (22.2%) when compared to HBV (3.9%). The mortality rate due to HCC associated with HBV showed a downward trend, and the mortality rate due to HCC associated with HCV showed a steady trend. Deaths of males, white individuals, those who aged from 50 to 59 years, and those who had 8–11 years of schooling predominated. Spatial analysis revealed a heterogeneous distribution of deaths in the state of São Paulo. Conclusions: The downward trend in mortality rates due to HCC associated with HBV shows an important advance in the disease control. However, the mortality rate due to HCC associated with HCV has remained stable throughout the study period. The spatial distribution of deaths may contribute to raise hypotheses for deeper knowledge of these diseases in the regions.

https://doi.org/10.1590/1980-549720220004

11.

Mortality due to hepatocellular carcinoma associated with hepatitis B and C viruses in the state of São Paulo, Brazil
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Cavalcante, Débora Ferro

; Garcia, Érica Marvila

; Farias, Norma Suely de Oliveira

; Koizumi, Inês Kazue

; Figueiredo, Gerusa Maria

; Sato, Ana Paula Sayuri

Revista Brasileira de Epidemiologia

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2022, Volume 25 elocation e220004

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720220004

12.

Meat quality of culled adult goats finished with increased feeding plans
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MARQUES, Iolly Tábata Oliveira

; FERNANDES, Cesar Carneiro Linhares

; VASCONCELOS, Fábio Roger

; ALVES, Juliana Paula Martins

; MONTENEGRO, Assis Rubens

; SILVA, Caroline Pessoa da

; OLIVEIRA, Felipe Brener Bezerra de

; FIGUEIREDO, Francisco Cardoso

; MOURA, Arlindo Araripe

; RONDINA, Davide

Food Science and Technology

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2022, Volume 42 elocation e37721

Abstract: En | Text: En | PDF: En

Abstract This study evaluated the effect of increasing the nutritional plane in finishing diets on meat quality traits of culled adult goats. Forty-one crossbred does were divided into four groups: baseline diet formulated to meet 100% of the nutritional requirements (BD); BD + 30% (BD30); + 60% (BD60); + 90% (BD90) of the nutritional level of BD. The goats received the experimental diets for 28 days. The protein profile of the longissimus lumborum muscle was evaluated using 1D SDS–PAGE and mass spectrometry. Cholesterol and albumin concentrations were highest in the BD group. There were no alterations in loin proximate composition or tissue composition. However, there was a significant reduction in the PUFA content in groups BD60 and BD90 compared with the group fed the baseline diet. Of 37 protein bands identified, 35 showed lower intensities in group BD90 than in BD and 22 bands showed lesser expression in groups BD60 and BD90 than in BD. The multivariate model identified 14 band proteins involved in group-diet segregation. Therefore, increasing the nutrient supply for finishing goats did not have marked positive effects on carcass. A lower expression of these proteins can have a profound impact on the qualitative aspects of the meat product.

https://doi.org/10.1590/fst.37721

13.

Relative Age Effect in Brazilian water polo: analysis of male and female athletes from U16 to senior categories
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de Oliveira Castro, Henrique

; Francisco, Paula Soares

; de Oliveira, Vivian

; Vasques, Dieisson Machado

; Monteiro, Gabriella Nelli

; Prado, Alexandre Konig Garcia

; Aburachid, Layla Maria Campos

; Figueiredo, Lucas Savassi

Motriz: Revista de Educação Física

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2022, Volume 28 elocation e10220002022

Abstract: En | Text: En | PDF: En

Abstract Aim: To investigate the existence of relative age effect (RAE) in Brazilian water polo athletes according to sex and age category. Methods: The birthdate of 574 Brazilian water polo athletes were organized according to the athletes’ birthdates into quarters of the year (Q1, Q2, Q3, and Q4), and classified according to sex (male and female) and age category (U16, U18, U20, and senior). To verify the existence of RAE, the Chi-Square tests (χ2) were performed, and the effect sizes (ω) were calculated for each of the tests. We also calculated odds ratio (ORs) and 95% confidence intervals, setting the level of significance to 0.05. As post hoc analysis, multiple comparisons between quarters were performed, with Bonferroni's correction (significance level set to 0.0083 in these cases). Results: The results indicated an uneven distribution of birthdates for male water polo athletes (χ2 = 12.257; p = 0.007; ω = 0.173), with an overrepresentation of athletes born in the first (p < 0.006) and second (p < 0.002) quarters. When sex and age category were considered, male athletes presented uneven distributions in U20 (χ2 = 10.747; p = 0.013; ω = 0.345) and senior (χ2= 12.614; p = 0.006; ω = 0.383) categories. In females, no differences were found. Conclusion: We conclude that there is an uneven distribution of birthdates in male Brazilian water polo athletes, indicating the presence of RAE in this group.

https://doi.org/10.1590/s1980-657420220002022

14.

A implantação em larga escala da Estratégia de Saúde da Família na cidade do Rio de Janeiro, Brasil: evidências e desafios
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Costa, Nilson do Rosário

; Silva, Iandara de Moura

; Lima, Paula Travassos de

; Silva, Thaís Severino da

; Costa, Isabel Cristina Maria da

; Figueiredo, Iara Veloso Oliveira

Ciência & Saúde Coletiva

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jun 2021, Volume 26 N. 6 Pages 2075 - 2082

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A cidade do Rio de Janeiro implantou em larga o modelo das Organizações Sociais (OSS) para a gestão da Atenção Primária à Saúde (APS). Esta opção torna a compreensão da experiência da cidade muito relevante, especialmente porque até então o modelo organizacional das OSS tinha sido adotado dominantemente na gestão hospitalar do SUS. Assim, é analisada a experiência de desenvolvimento da APS em dois momentos conflitantes da gestão municipal em relação ao modelo das OSS: a implantação e desenvolvimento das PPP (2009-2016); e o seu desmantelamento (2017-2020). Utilizou-se o Estudo de Caso, Revisão Bibliográfica e análise dos dados públicos do DATASUS/Ministério da Saúde. Identificou-se que: a adoção da terceirização com base nas OSS pode ser diretamente associada à rápida expansão da APS na cidade e a melhoria de indicadores de cobertura da APS; que a difusão do modelo das OSS está associada à alta prioridade dada ao gasto com saúde no orçamento municipal; que a sustentabilidade da adoção do modelo da OSS não foi dependente da condição econômica do município, mas da escolha política do governo no período 2009-2016. O arranjo das PPP produziu avanços organizacionais importantes, mas não impediram o veto ao modelo das OSS levada adiante ao longo da gestão de 2017-2020.

Abstract The city of Rio de Janeiro has implemented, on a large scale, the model of Social Organizations (OSS) for the management of Primary Health Care (PHC). This option makes the understanding of the city’s experience very relevant, especially since, until then, the OSS organizational model had been adopted predominantly in the SUS hospital management. Thus, the experience of PHC development at two conflicting moments of municipal management in relation to the OSS model is analyzed: the implementation and development of the PPPs (2009-2016); and their dismantling (2017-2020). Case Studies, Literature Review and analysis of public data from DATASUS/Ministry of Health were used. It was verified that: the adoption of outsourcing based on OSS can be directly associated with the rapid expansion of PHC in the city and PHC coverage improvement indicators; the diffusion of the OSS model is associated with the high priority given to health expenditures in the municipal budget; the sustainability of the adoption of the OSS model did not depend on the municipality’s economic status, but on the government’s political choice in the period of 2009 to 2016. The PPP arrangement resulted in important organizational advances, although it did not prevent the veto of the OSS model carried out during the 2017-2020 term.

https://doi.org/10.1590/1413-81232021266.01012021 207 downloads

15.

A implantação em larga escala da Estratégia de Saúde da Família na cidade do Rio de Janeiro, Brasil: evidências e desafios
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Costa, Nilson do Rosário

; Silva, Iandara de Moura

; Lima, Paula Travassos de

; Silva, Thaís Severino da

; Costa, Isabel Cristina Maria da

; Figueiredo, Iara Veloso Oliveira

Ciência & Saúde Coletiva

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jun 2021, Volume 26 N. 6 Pages 2075 - 2082

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232021266.01012021

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