Abstract: The objective of this study was to evaluate the quality of milk and cheese and sensory analysis of cheese from goats that received a diet with different levels of sorghum silage in the diet. Twenty Anglonubian dairy goats were used, with an average age of 2 years, average live weight of 43.7 kg, distributed in a completely randomized design, with five replications. Moisture (P=0.001), total solids (P=0.001), fat (p=0.001), TDE (P=0.006) and protein (P=0.003) of goat cheese showed a significant difference due to the inclusion of silage from goat cheese. sorghum in the diet. The sensory attributes soft appearance (P<.0001), look (P<.0001), salty taste (P<.0001) and smooth texture (P=0.0430) showed a significant difference depending on the level of sorghum silage added to the diet. of goats. In the PC analysis, it is observed that three main components were needed to represent the variation of 64.84% of the data. PC 1 determined 29% of the data variation and was represented by the attributes with the highest averages: attractive aroma (5.87) and global acceptability (7.74). The inclusion of up to 45% of sorghum silage in the diet of goats increased milk and cheese fat, which favored high scores for the attributes of softness and global acceptance.

OBJECTIVE: To evaluate the effectiveness and safety of first-generation protease inhibitors for the treatment of genotype 1 hepatitis C virus-infected patients at Brazilian reference centers. METHODS: This multicenter cross-sectional study included hepatitis C virus genotype 1 monoinfected patients treated with Peg-interferon, ribavirin, and either boceprevir (n=158) or telaprevir (n=557) between July 2013 and April 2014 at 15 reference centers in Brazil. Demographic, clinical, virological, and adverse events data were collected during treatment and follow-up. RESULTS: Of the 715 patients, 59% had cirrhosis and 67.1% were treatment-experienced. Based on intention-to-treat analysis, the overall sustained viral response was 56.6%, with similar effectiveness in both groups (51.9% for boceprevir and 58% for telaprevir, p=0.190). Serious adverse events occurred in 44.2% of patients, and six deaths (0.8%) were recorded. Cirrhotic patients had lower sustained viral response rates than non-cirrhotic patients (46.9% vs. 70.6%, p<0.001) and a higher incidence of serious adverse events (50.7% vs. 34.8%, p<0.001). Multivariate analysis revealed that sustained viral response was associated with the absence of cirrhosis, viral recurrence after previous treatment, pretreatment platelet count greater than 100,000/mm3, and achievement of a rapid viral response. Female gender, age>65 years, diagnosis of cirrhosis, and abnormal hemoglobin levels/platelet counts prior to treatment were associated with serious adverse events. CONCLUSION: Although serious adverse events rates were higher in this infected population, sustained viral response rates were similar to those reported for other patient cohorts.

Este estudo objetiva conhecer as concepções sobre a sexualidade de profissionais de enfermagem que atuam na atenção primária em saúde e identificar como essa temática integra as práticas assistenciais desses profissionais a mulheres nutrizes. Trata-se de pesquisa qualitativa, exploratória e descritiva, cujos sujeitos foram oito profissionais de enfermagem atuantes em três unidades de atenção primária em saúde de município do Norte do Rio Grande do Sul. A coleta dos dados realizou-se via entrevistas semiestruturadas. Para seu tratamento foi utilizada a análise de conteúdo temática, da qual emergiram três temas: concepção sobre sexualidade; a sexualidade e a amamentação; sexualidade e práticas de enfermagem voltadas à mulher nutriz. O estudo permitiu constatar que os profissionais de enfermagem entendem o sentido amplo que a sexualidade representa e a relação que tem com a amamentação, porém não a abordam ao assistirem a mulher em processo de amamentação, sendo suas práticas sustentadas em abordagem biomédica.

The objective of this study is to identify the primary health care nurses' concepts about sexuality, and how this theme is integrated within the health care practices of these professionals when working with breastfeeding women. This qualitative, exploratory and descriptive study was performed with eight nurses from three primary health care units in a city in the north region of Rio Grande do Sul state. Data collection was performed through semi-structured interviews. Thematic content analysis revealed three themes: ideation about sexuality; sexuality and breastfeeding; and sexuality and nursing practices aimed at the breastfeeding woman. The study revealed that nursing professionals understand the broad meaning that sexuality represents and the relationship it has with breastfeeding, but they do not approach this theme in the care provided to women engaged in the breastfeeding process, thus their practices are grounded in the biomedical approach.

Se objetiva conocer las concepciones sobre sexualidad de profesionales de enfermería actuantes en atención primaria de salud e identificar el modo en que la temática integra las prácticas asistenciales de tales profesionales a mujeres que amamantan. Investigación cualitativa, exploratoria, descriptiva, cuyos sujetos fueron ocho profesionales de enfermería actuantes en tres unidades de atención primaria de salud de municipio norteño de Rio Grande do Sul. Datos fueran recolectados mediante entrevistas semiestructuradas. Para su tratamiento se utilizó análisis de contenido temático. Emergieron tres temas: concepción sobre sexualidad; sexualidad y lactancia; sexualidad y prácticas de enfermería orientadas a la mujer que amamanta. Se constató que los profesionales de enfermería entienden el sentido amplio que la sexualidad representa y la relación que tiene con el amamantamiento, no obstante lo cual no la aborda al atender a mujeres en proceso de amamantamiento, sustentándose sus prácticas en abordaje biomédico.

The objective of this study is to identify the primary health care nurses' concepts about sexuality, and how this theme is integrated within the health care practices of these professionals when working with breastfeeding women. This qualitative, exploratory and descriptive study was performed with eight nurses from three primary health care units in a city in the north region of Rio Grande do Sul state. Data collection was performed through semi-structured interviews. Thematic content analysis revealed three themes: ideation about sexuality; sexuality and breastfeeding; and sexuality and nursing practices aimed at the breastfeeding woman. The study revealed that nursing professionals understand the broad meaning that sexuality represents and the relationship it has with breastfeeding, but they do not approach this theme in the care provided to women engaged in the breastfeeding process, thus their practices are grounded in the biomedical approach.

Se objetiva conocer las concepciones sobre sexualidad de profesionales de enfermería actuantes en atención primaria de salud e identificar el modo en que la temática integra las prácticas asistenciales de tales profesionales a mujeres que amamantan. Investigación cualitativa, exploratoria, descriptiva, cuyos sujetos fueron ocho profesionales de enfermería actuantes en tres unidades de atención primaria de salud de municipio norteño de Rio Grande do Sul. Datos fueran recolectados mediante entrevistas semiestructuradas. Para su tratamiento se utilizó análisis de contenido temático. Emergieron tres temas: concepción sobre sexualidad; sexualidad y lactancia; sexualidad y prácticas de enfermería orientadas a la mujer que amamanta. Se constató que los profesionales de enfermería entienden el sentido amplio que la sexualidad representa y la relación que tiene con el amamantamiento, no obstante lo cual no la aborda al atender a mujeres en proceso de amamantamiento, sustentándose sus prácticas en abordaje biomédico.

Este estudo objetiva conhecer as concepções sobre a sexualidade de profissionais de enfermagem que atuam na atenção primária em saúde e identificar como essa temática integra as práticas assistenciais desses profissionais a mulheres nutrizes. Trata-se de pesquisa qualitativa, exploratória e descritiva, cujos sujeitos foram oito profissionais de enfermagem atuantes em três unidades de atenção primária em saúde de município do Norte do Rio Grande do Sul. A coleta dos dados realizou-se via entrevistas semiestruturadas. Para seu tratamento foi utilizada a análise de conteúdo temática, da qual emergiram três temas: concepção sobre sexualidade; a sexualidade e a amamentação; sexualidade e práticas de enfermagem voltadas à mulher nutriz. O estudo permitiu constatar que os profissionais de enfermagem entendem o sentido amplo que a sexualidade representa e a relação que tem com a amamentação, porém não a abordam ao assistirem a mulher em processo de amamentação, sendo suas práticas sustentadas em abordagem biomédica.