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Abstract Objective: To investigate the usefulness, reliability, quality, and content of Portuguese-language YouTube videos on COVID-19. Material and Methods: Three keywords selected on Google Trends were searched on YouTube, and the 60 first videos listed with each term were analyzed. Two calibrated researchers evaluated the reliability (DISCERN Modified Scale), the quality (Global Quality Score - GQS), and the usefulness of videos for the users (COVID-19 Specific Score - CSS). The number of views, likes, and engagement were also analyzed. The data were evaluated by the Mann-Whitney test and Spearman correlation (α=5%). Results: 59 videos were included. The average scores of quality, reliability, and usefulness were 3.0 (±1.1), 3.2 (± 0.8), and 1.5 (± 0.9), respectively. Two-thirds of the videos (64.4%) had low/moderate quality, and the majority (76.2%) were about signs and symptoms. The numbers of views (p=0.005), likes (p=0.006), and engagement (p=0.014) were significantly higher in moderate/good quality videos. The number of comments (p=0.007), duration of videos (p=0.004), and the DISCERN score (p<0.001) were significantly higher in videos made by health professionals. The general quality of the videos was positively correlated to the CSS scores, number of views, likes, and engagement (p<0.05). Conclusion: Most videos had moderate quality and reliability and low usefulness for the users.

https://doi.org/10.1590/pboci.2024.009

Autoinflammatory diseases: a Latin American multicenter study according to age and sex
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Piotto, Daniela Gerent Petry

; Kozu, Katia

; Aikawa, Nádia Emi

; Carneiro, Pedro Lopes

; Katsicas, María Martha

; Oliveira, Sheila Knupp Feitosa de

; Fernandes, Taciana de Albuquerque Pedrosa

; Magalhães, Claudia Saad

; Cunha, Ana Luiza Garcia

; Bica, Blanca Elena Rios Gomes

; Rabelo Júnior, Carlos Nobre

; Battagliotti, Cristina

; Matos, Erica Naomi Naka

; Santos, Flavia Patrícia Sena Teixeira

; Sztajnbok, Flavio Roberto

; Bezrodnik, Liliana

; Bandeira, Marcia

; Rodrigues, Marta Cristine Felix

; Munittis, Pablo García

; Appenzeller, Simone

; Robazzi, Teresa Cristina Martins

; Clemente, Gleice

; Silva, Clovis Artur

; Terreri, Maria Teresa

Revista Paulista de Pediatria

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2024, Volume 42 elocation e2022184

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To evaluate autoinflammatory diseases (AID) according to age at diagnosis and sex, and response to therapy in a large population. Methods: This is a cross-sectional observational study of a Latin American registry using a designed web system for data storage, collected between 2015 and 2018. Any altered findings during follow-up were recorded. The forms were translated into Portuguese and Spanish, including demographic, clinical, laboratory, genetic and treatment characteristics. Results: We included 152 patients, 51.3% male and 75% Caucasian. The median age at disease onset was 2.1 years (0–15.6 years) and median age at diagnosis 6.9 years (0–21.9 years); 111 (73%) were children (0–9 years old), and 41 (27%) were adolescents and young adults (AYA) (10–21 years old). Periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome (PFAPA) occurred in 46/152 (30%), chronic non-bacterial osteomyelitis (CNO) in 32/152 (21%), and familial Mediterranean fever (FMF) in 24/152 (15.7%). PFAPA was significantly higher in young children than in AYA (38.7% vs. 7.3%, p<0.001), while CNO were lower (13.5% vs. 41.5%, p<0.001). The frequency of females was significantly higher in CNO (28.4% vs. 14.1%, p=0.031) and lower in FMF (8.1% vs. 23.1%, p=0.011). The most used drugs were glucocorticoids, non-steroidal anti-inflammatory drugs (NSAID), and colchicine. Glucocorticoids and colchicine treatment were used in all AID with good to moderate response. However, cryopyrin-associated periodic syndromes (CAPS) seemed unresponsive to glucocorticoids. NSAIDs and methotrexate were the main medications used to treat CNO. Conclusions: Differences among AID patients were observed in the LA population regarding sex and age at disease diagnosis.

RESUMO Objetivo: Avaliar as doenças autoinflamatórias (DAI) de acordo com sexo e idade no momento do diagnóstico e a resposta terapêutica em uma grande população. Métodos: Este é um estudo observacional transversal de um registro latino-americano que usou um sistema de dados coletados entre 2015 e 2018. Quaisquer achados alterados ao longo do acompanhamento foram registrados. Os formulários foram traduzidos para os idiomas português e espanhol, incluindo características demográficas, clínicas, laboratoriais, genéticas e de tratamento. Resultados: Incluímos 152 pacientes, sendo 51,3% do sexo masculino e 75% da raça branca. A média de idade de início da doença foi de 2,1 anos (0–15,6 anos) e a média de idade de diagnóstico 6,9 anos (0–21,9 anos); 111 (73%) eram crianças (0–9 anos) e 41 (27%) adolescentes/adultos jovens (10–21 anos). A síndrome de febre periódica, estomatite aftosa, faringite e adenite (PFAPA) ocorreu em 46/152 (30%), osteomielite não bacteriana crônica (CNO) em 32/152 (21%) e febre familiar do Mediterrâneo (FMF) em 24/152 (15,7%). A PFAPA foi significativamente maior em crianças pequenas (38,7 vs. 7,3%, p<0,001), e a CNO, em adolescentes/adultos jovens (13,5 vs. 41,5%, p<0,001). A frequência do sexo feminino foi significativamente maior na CNO (28,4 vs. 14,1%, p=0,031) e menor na FMF (8,1 vs. 23,1%, p=0,011). Os medicamentos mais utilizados foram glicocorticoides, anti-inflamatórios não esteroidais (AINE) e colchicina. O tratamento com glicocorticoides e colchicina foi usado em todas as DAI com resposta boa a moderada. No entanto, as síndromes periódicas associadas à criopirina (CAPS) pareciam não responder aos glicocorticoides. AINE e metotrexato foram os principais medicamentos utilizados no tratamento da CNO. Conclusões: Diferenças de pacientes com DAI foram observadas na população latino-americana em pacientes agrupados por sexo e idade ao diagnóstico da doença.

https://doi.org/10.1590/1984-0462/2024/42/2022184

Pollen Available During Anthesis of Hylocereus Undatus Flowers
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Del Ángel-Pérez, Ana Lid

; Nataren-Velazquez, Jeremías

; Megchun-Garcia, Juan Valente

; Martínez-Hernández, María de Jesús

; Estrada-López, Mariel

Enfoque UTE

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dec 2023, Volume 14 N. 4 Pages 53 - 63

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen: La pitahaya (Hylocereus spp) es un fruto que, por las características de su demanda, tanto para fruta fresca como para consumo industrial, ha detonado fuertemente su desarrollo en diversos países. in embargo, presenta diversos mecanismos de autoincompatibilidad que impacta en la productividad. Por lo anterior, se analizó la viabilidad del polen durante la antesis (o periodo de floración) de dos cultivares de H. undatus de pulpa blanca. Para ello se tomó muestras de polen durante 13 horas, desde el comienzo de ésta por la tarde, hasta que finaliza al día siguiente. El método utilizado fue tinción con sal de tetrazolio (cloruro de 2,3,5-trifeniltetrazolio) o TZ. Los resultados mostraron que no hay polen viable al inicio de la antesis. A las 09:00 pm la viabilidad comenzó a crecer lentamente y después de las 12:00 am se duplicó y se aceleró la viabilidad, marcando la más alta de 02:00 a 04:00 am. Se pudo observar la consistencia del polen que inicia con una fase I con polen húmedo sin viabilidad, hasta otra con menor humedad con baja viabilidad (fase II). La fase III, observó polen harinoso muy granulado, fácil de manejar precisamente cuando las lecturas de la tinción marcaron la viabilidad de 93 % a 95 %. Posteriormente, la viabilidad baja hasta desaparecer cuando la estructura floral comienza a deshidratarse.

Abstract: Pitahaya (Hylocereus spp) is a fruit that, due to the characteristics of its demand, both for fresh fruit and for industrial consumption, has detonated its development in various countries. However, it presents various self-incompatibility mechanisms that impact productivity. Therefore, the viability of pollen was analyzed during the anthesis (or flowering period)of two white-fleshed H. undatus cultivars, taking pollen samples for 13 hours, from the beginning of the anthesis in the afternoon, until it ends the following day. The method used was staining with tetrazolium salt (2,3,5-triphenyltetrazolium chloride) or TZ. The results showed that there is no viable pollen at the beginning of the anthesis. At 09:00 pm the viability began to grow slowly and after 12:00 am it doubled and the viability accelerated, marking the highest from 02:00 to 04:00 am. It was possible to observe the consistency of the pollen that begins with a phase I with humid pollen without viability, up to another with lower humidity with low viability (phase II). Phase III observed very granular mealy pollen, easy to handle precisely when the staining readings marked the viability of 93 % to 95 %. Subsequently, the viability decreases until it disappears when the floral structure begins to dehydrate.

https://doi.org/10.29019/enfoqueute.976

Qualidade de vida e engajamento no trabalho em profissionais de enfermagem no início da pandemia de COVID-19
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Carvalho, Taisa Moitinho de

; Lourenção, Luciano Garcia

; Pinto, Maria Helena

; Viana, Renata Andrea Pietro Pereira

; Moreira, Ana Maria Batista da Silva Gonçalves

; Mello, Leticia Pepineli de

; Medeiros, Gilney Guerra de

; Gomes, Antonio Marcos Freire

Ciência & Saúde Coletiva

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oct 2023, Volume 28 N. 10 Pages 2903 - 2913

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O artigo investiga a correlação entre engajamento e qualidade de vida no trabalho dos profissionais de enfermagem de um hospital público do interior do estado de São Paulo, no início da pandemia de COVID-19. Estudo transversal, descritivo e correlacional, com profissionais de enfermagem, realizado entre dezembro de 2020 e janeiro de 2021. Foram utilizadas as versões brasileiras da Utrecht Work Engagement Scale (UWES) e da Escala de Avaliação da Qualidade de Vida no Trabalho (QVT), segundo modelo de Walton. Os profissionais de enfermagem apresentaram correlação forte e positiva (r≥0.70) entre o domínio integração social da QVT e a dimensão vigor da UWES (r=0,88; p=<0,001); correlação positiva moderada (r≥0.40≤0.69) entre as condições de trabalho (QVT) e as dimensões vigor (r=0,40; p=<0,001), dedicação (r=0,40; p=<0,001) e escore geral (r=0,41; p=<0,001) da UWES. As correlações foram positivas e fracas (r≤0.39) para os demais domínios da QVT e as dimensões da UWES. Concluiu-se que os profissionais com níveis satisfatórios de qualidade de vida tendem a ter níveis mais altos de engajamento no trabalho. No início da pandemia de COVID-19, os profissionais de enfermagem estavam fortemente engajados e satisfeitos com sua qualidade de vida no trabalho.

Abstract This article investigates the correlation between work engagement and work-related quality of life among nursing staff at a public hospital in São Paulo State, at the onset of the COVID-19 pandemic. A descriptive, correlational, cross-sectional study of nursing personnel was conducted from December 2020 to January 2021, using the Brazilian versions of the Work & Well-being Survey (Utrecht Work Engagement Scale - UWES) and the Work-related Quality of Life (WRQoL) scale, following Walton’s model. Nursing staffs returned a strong positive correlation (r≥0.70) between the social integration domain of the WRQoL and the vigour dimension of the UWES (r=0.88; p=<0.001); a moderate positive correlation (r≥0.40≤0.69) between working conditions (WRQOL) and the vigour (r=0.40; p<0.001), dedication (r=0.40; p<0.001) and overall score (r=0.41; p<0.001) dimensions of the UWES. Correlations were positive and weak (r≤0.39) for the other WRQoL domains and the UWES dimensions. It was concluded that personnel with satisfactory levels of quality of life tend to show higher levels of engagement at work. At the onset of the COVID-19 pandemic, nursing professionals were strongly engaged and satisfied with their work-related quality of life.

https://doi.org/10.1590/1413-812320232810.09982023

Seeking treatment for traumatic dental injuries in schoolchildren: A multilevel analysis
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Bernardino, Veruska Medeiros Martins

; Lima, Larissa Chaves Morais de

; Araújo, Luiza Jordânia Serafim de

; Neves, Érick Tássio Barbosa

; Ferreira, Fernanda de Morais

; Granville-Garcia, Ana Flávia

Brazilian Dental Journal

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oct 2023, Volume 34 N. 5 Pages 95 - 103

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT To investigate individual and contextual factors associated with seeking treatment for traumatic dental injuries. A cross-sectional study was conducted with 739 pairs of guardians and children. Guardians answered a questionnaire addressing sociodemographic characteristics, seeking treatment for a tooth injury in the child, and the Oral Health Literacy-Adult Questionnaire. Descriptive analysis and unadjusted and adjusted multilevel Poisson regression analysis (p<0.05). The prevalence of seeking treatment for traumatic dental injury was 44.7%. Sociodemographic variables associated were white skin of the child (PR = 1.30; 95% CI: 1.08-1.76), mother’s age older than 35 years (PR = 1.70; 95% CI: 1.50-1.90), married parents (PR = 1.93; 95% CI: 1.70-2.23), guardians with more than eight years of schooling (PR = 2.00; 95% CI: 1.76-2.23), with adequate oral health literacy (PR = 3.33; 95% CI: 3.01-3.62) and the daily use of electronic devices by the child (PR = 1.26; 95% CI: 1.02-1.50). On the contextual level, attending a private school (PR = 1.77; 95% CI: 1.02-3.05) and the number of primary care units with oral health teams in the school district (PR = 1.78; 95% CI: 1.12-2.38) remained associated. Among the children who suffered TDI, adequate oral health literacy on the part of the parents stood out among the factors associated with seeking treatment.

Resumo Investigar fatores individuais e contextuais associados à busca de tratamento para lesões dentárias traumáticas. Foi realizado um estudo transversal com 739 pares de responsáveis e crianças. Os responsáveis responderam a um questionário abordando características sociodemográficas, busca por tratamento para traumatismo dentário na criança e o Questionário de alfabetização em saúde bucal para adulto. Análise descritiva e análise de regressão de Poisson multinível não ajustada e ajustada (p<0,05) foram realizadas. A prevalência de busca de tratamento para lesão dentária traumática foi de 44,7%. As variáveis sociodemográficas associadas foram a pele branca da criança (RP = 1,30; IC 95%: 1,08-1,76), idade da mãe maior que 35 anos (RP = 1,70; IC 95%: 1,50-1,90), os responsáveis casados (RP = 1,93; IC 95%: 1,70-2,23), com mais de oito anos de estudo (RP = 2,00; IC 95%: 1,76-2,23), com alfabetização adequada em saúde bucal (RP = 2,00; IC 95%: 1,76-2,23) e uso diário de dispositivos eletrônicos pela criança (RP = 1,26; IC 95%: 1,02-1,50). No nível contextual, frequentar uma escola particular (PR = 1,77; IC 95%: 1,02-3,05) e a quantidade de unidades básicas de saúde com equipes de saúde bucal no distrito sanitário da escola (PR = 1,78; IC 95%: 1,12-2,38) permaneceram associados. Entre as crianças que sofreram TDI, a alfabetização em saúde bucal adequada dos pais foi um fator que se destacou na busca por tratamento.

https://doi.org/10.1590/0103-6440202305555

Cross-cultural adaptation of the Digital Health Literacy Instrument (DHLI) for use on Brazilian adolescents
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Barbosa, Mariane Carolina Faria

; Baldiotti, Ana Luiza Peres

; Braga, Náyra Santos

; Lopes, Camila Takáo

; Paiva, Saul Martins

; Granville-Garcia, Ana Flávia

; Ferreira, Fernanda de Morais

Brazilian Dental Journal

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oct 2023, Volume 34 N. 5 Pages 104 - 114

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The present study aimed to perform the cross-cultural adaptation of the Digital Health Literacy Instrument (DHLI) for native Brazilian Portuguese-speaking adolescents (DHLI-BrA). Cross-cultural adaptation consisted of the following steps: translation, assessment, and adjustments by the expert committee to ensure cultural equivalence; back-translation, and synthesis of back-translations. Cognitive testing was then performed in a pretest with adolescents using cognitive interviews with probing questions on the item's understanding interpretation and response options. Cronbach’s alpha coefficient and McDonald’s omega were used to estimate the instrument’s reliability. Forty-two Brazilian adolescents participated in the study (mean age: 16.0 ± 2.0 years; range: 13 to 19 years). Items that were difficult to understand were adapted to the context of Brazilian adolescents. Cronbach’s alpha coefficient and McDonald’s omega for the 21 items of the DHLI-BrA were, respectively, 0.79 and 0.80. Cronbach’s alpha coefficient for the subscales of the self-report instrument was 0.53-0.79 (range), demonstrating good reliability in the total instrument and moderate reliability in the subscales. This study provides the cross-cultural adapted version of the Digital Health Literacy Instrument (DHLI), which is an instrument for measuring digital Health literacy, for use in Brazilian adolescents (DHLI-BrA).

Resumo O estudo teve o objetivo de adaptar transculturalmente o Digital Health Literacy Instrument (DHLI) para adolescentes nativos do idioma português do Brasil (DHLI-BrA). O estudo de adaptação transcultural consistiu nas seguintes etapas: tradução, avaliação e adequação de equivalência cultural da tradução por comitê de especialistas; retrotradução e síntese das retrotraduções. Foi realizada a testagem cognitiva em pré-teste com adolescentes, utilizando-se entrevistas cognitivas com perguntas de sondagem sobre a compreensão e interpretação dos itens e opções de resposta. O alfa de Cronbach e ômega de McDonald’s foram utilizados para estimar a confiabilidade do instrumento. Participaram do pré-teste 42 adolescentes brasileiros com média de idade de 16,0 ± 2,0 (variação de 13-19) anos. Os itens com dificuldade de compreensão foram adaptados ao contexto dos adolescentes brasileiros. O coeficiente alfa de Cronbach e o ômega de McDonald’s, para os 21 itens do DHLI-BrA foi respectivamente, 0,79 e 0,80. O coeficiente alfa de Cronbach para as subescalas do instrumento de autorrelato foi de 0,53-0,79 (variação), demonstrando boa confiabilidade no instrumento total e confiabilidade moderada nas subescalas. Este estudo fornece a versão adaptada transculturalmente do Digital Health Literacy Instrument (DHLI), um instrumento de mensuração do letramento digital em saúde, para utilização em adolescentes brasileiros (DHLI-BrA).

https://doi.org/10.1590/0103-6440202305346

Qualidade de vida e engajamento no trabalho em profissionais de enfermagem no início da pandemia de COVID-19
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Carvalho, Taisa Moitinho de

; Lourenção, Luciano Garcia

; Pinto, Maria Helena

; Viana, Renata Andrea Pietro Pereira

; Moreira, Ana Maria Batista da Silva Gonçalves

; Mello, Leticia Pepineli de

; Medeiros, Gilney Guerra de

; Gomes, Antonio Marcos Freire

Ciência & Saúde Coletiva

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oct 2023, Volume 28 N. 10 Pages 2903 - 2913

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-812320232810.09982023

La vacuna de ARNm para el tratamiento del cáncer de páncreas llegó para quedarse
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Chuluyan, Eduardo

; Davio, Carlos

; Dusetti, Nelson

; Fraunhoffer, Nicolás

; Garcia, María Noé

; Garona, Juan

; González, Betina

; Gottardo, Florencia

; Grasso, Daniel

; Iovanna, Juan

; Kohan, Gustavo

; Lada, Paul Eduardo

; Mazza, Oscar

; Monte, Martín

; Papademetrio, Daniela

; Pasqualini, María Eugenia

; Sahores, Ana

; Santofimia, Patricia

; Yaneff, Agustín

Medicina (Buenos Aires)

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aug 2023, Volume 83 N. 4 Pages 650 - 652

Abstract: Es | Text: Es | PDF: Es

Improving the quality of publications in and advancing the entire paradigms of clinical and social pharmacy practice research: the Granada statements
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Fernandez-Llimos, Fernando

; Desselle, Shane

; Stewart, Derek

; Garcia-Cardenas, Victoria

; Babar, Zaheer-Ud-Din

; Bond, Christine

; Dago, Ana

; Jacobsen, Ramune

; Nørgaard, Lotte Stig

; Polidori, Carlo

; Sánchez-Polo, Manuel

; Santos-Ramos, Bernardo

; Shcherbakova, Natalia

; Tonin, Fernanda S

Ars Pharmaceutica (Internet)

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jun 2023, Volume 64 N. 2 Pages 161 - 172

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as “the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care”. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other health care areas (i.e., medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into six topics: the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics, and authors' selection of the most appropriate pharmacy practice journal to submit their work.

Resumen La farmacia y las ciencias farmacéuticas abarcan una serie de disciplinas diferentes. La Farmacia Asistencial se ha definido como “la disciplina científica que estudia los diferentes aspectos de la práctica de la farmacia y su impacto en los sistemas de atención de la salud, el uso de medicamentos y la atención al paciente”. Por lo tanto, los estudios de Farmacia Asistencial abarcan tantos elementos de farmacia clínica como de farmacia social. Como cualquier otra disciplina científica, la práctica de la farmacia clínica y social difunde los resultados de la investigación utilizando revistas científicas. Los editores de revistas de farmacia clínica y farmacia social tienen un papel en la promoción de la disciplina al mejorar la calidad de los artículos publicados. Como ha ocurrido en otras áreas del cuidado de la salud (es decir, medicina y enfermería), un grupo de editores de revistas de práctica farmacéutica clínica y social se reunió en Granada, España, para discutir cómo las revistas pueden contribuir a fortalecer la práctica farmacéutica como disciplina. El resultado de esa reunión se compiló en estas Declaraciones de Granada, que comprenden 18 recomendaciones reunidas en seis temas: el uso apropiado de la terminología, los resúmenes con impacto, la necesidad de la revisión por pares, la dispersión de revistas, el uso más eficaz y más inteligente de los indicadores bibliométricos y la selección por parte de los autores de la revista de práctica farmacéutica más adecuada para presentar su trabajo.

https://doi.org/10.30827/ars.v64i2.27182

10.

PCR identification of lactic acid bacteria populations in corn silage inoculated with lyophilised or activated Lactobacillus buchneri
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Santos, Ana Paula Maia dos

; Santos, Edson Mauro

; Silva de Oliveira, Juliana

; Garcia Leal de Araújo, Gherman

; de Moura Zanine, Anderson

; Araújo Pinho, Ricardo Martins

; Costa do Nascimento, Thiago Vinicius

; Fernandes Perazzo, Alexandre

; Ferreira, Daniele de Jesus

; da Silva Macedo, Alberto Jefferson

; de Sousa Santos, Francisco Naysson

Revista de la Facultad de Ciencias Agrarias. Universidad Nacional de Cuyo

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jun 2023, Volume 55 N. 1 Pages 115 - 125

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Este estudio tuvo como objetivo evaluar el efecto de la inoculación con L. buchneri liofilizado y/o activado sobre las poblaciones de bacterias de ácido láctico en ensilajes de maíz. Los tratamientos experimentales consistieron en ensilaje de maíz sin aditivo y ensilaje con los inoculantes L. buchneri 1 × 10 5 ufc/g, aplicados según las recomendaciones del fabricante (1 g/tonelada de forraje) en las formas de inoculante liofilizado e inoculante preactivado. Se identificaron aislados purificados de ensilajes de maíz con y sin inocu lación, y el 93% de los aislados correspondieron a bacterias de ácido láctico de la especie L. plantarum. Entre los aislados no se detectaron bacterias de la especie L. buchneri. La aplicación de L. buchneri liofilizado o activado en la masa ensilada promueve un aumento considerable de la población de bacterias de ácido lácticas en los ensilajes de maíz durante todo el período de fermentación.

Abstract This study aimed to evaluate the effect of inoculation with lyophilised and/or activated Lactobacillus buchneri on lactic acid bacteria populations in corn silage. Experimental treatments consisted of corn silage without additives or silage with the inoculants of L. buchneri (1 x 10 5 cfu/g) applied according to the manufacturer’s recommendations (1 g/tonne fodder) in the forms of the lyophilised inoculant and pre-activated inoculant. Purified isolates from corn silage with and without the inoculant were identified, and 93% of the isolates corresponded to the lactic acid bacteria of the species Lactobacillus plantarum. Among the isolates, no bacteria of the species L. buchneri were detected. The application of lyophilised or activated L. buchneri improved the microbiological profile and reduced ethanol production in corn silage, even without being identified among the isolates captured 70 days after ensilage.

11.

Hypersensitivity reaction to Patent Blue Dye
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Presa, Ana R.

; Garcia, Sónia

; Cadinha, Susana

; Sousa, Maria João

Revista Portuguesa de Imunoalergologia

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jun 2023, Volume 31 N. 2 Pages 163 - 167

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Patent Blue Dye (PBD) is a synthetic blue dye commonly used in medical practice for sentinel lymph node mapping in breast cancer. The authors report the case of a patient with invasive ductal carcinoma of the left breast, who underwent unilateral mastectomy with sentinel lymph node mapping. During surgery, the patient developed violaceous urticaria and mild glottic edema. A hypersensitivity reaction to PBD was confirmed by skin prick tests and methylene blue was identified as a possible alternative dye. This article reinforces the need for greater awareness of the possible hypersensitivity reactions to PBD during surgical procedures.

RESUMO O Azul patente (AP) é um corante azul sintético comummente usado na prática clínica para o mapeamento do gânglio sentinela no cancro da mama. Os autores reportam o caso de uma doente com carcinoma ductal invasivo da mama esquerda, submetida a mastectomia unilateral com mapeamento de gânglio sentinela. Durante a cirurgia, a doente desenvolveu urticária violácea e edema glótico ligeiro. Foi confirmada reação de hipersensibilidade ao AP através de testes cutâneos, tendo sido identificado o azul-de-metileno como um possível corante alternativo. Este caso reforça a necessidade de maior consciencialização sobre as possíveis reações de hipersensibilidade ao AP durante procedimentos cirúrgicos.

https://doi.org/10.32932/rpia.2023.06.114

12.

The bycatch of piramutaba, Brachyplatystoma vaillantii industrial fishing in a salinity and depth gradient in the Amazon estuary, Brazil
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MARCENIUK, Alexandre Pires

; SOARES, Bruno Eleres

; ROTUNDO, Matheus Marcos

; CAIRES, Rodrigo Antunes

; ROSA, Ricardo de Souza

; SANTOS, Wagner César Rosa dos

; CORDEIRO, Ana Patrícia Barros

; ROMÃO JUNIOR, João Gomes

; AKAMA, Alberto

; WOSIACKI, Wolmar Benjamin

; KLAUTAU, Alex Garcia Cavalleiro de Macedo

; CINTRA, Israel Hidenburgo Aniceto

; BARTHEM, Ronaldo

Acta Amazonica

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jun 2023, Volume 53 N. 2 Pages 93 - 106

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The piramutaba, Brachyplatystoma vaillantii is a freshwater catfish that is the most abundant fishery resource in the Amazon estuary. Piramutaba trawling is done on industrial fishing scale and is characterized by the presence of many freshwater and marine bycatch species, with and without commercial value. Here we describe the bycatch of the industrial fishery of piramutaba in the Amazon estuary and evaluate the relationship of two important environmental factors, depth and salinity, with the accidental capture of freshwater and marine fishes in the Amazon estuary in the rainy and dry seasons. We identified 21 cartilaginous fish species (19.1% freshwater and 80.9% marine) and 125 bony fish species (25.6% freshwater and 74.4% marine). The bycatch included 64 species without commercial value (43% of all bycatch species), which are always discarded. Freshwater and estuarine fishes exhibited significantly higher abundances in shallower environments, while marine fishes were similarly abundant along the entire depth gradient. On the contrary, the abundance of freshwater fishes significantly decreased, and that of estuarine and marine fishes significantly increased with increasing salinity. Regarding the conservation status of the bycatch species, one is classified as vulnerable (VU), and seven as critically endangered (CR). The information on the bycatch of piramutaba fishery in the Amazon estuary is important to subsidize regional fisheries policies and the management of protected areas.

RESUMO A piramutaba, Brachyplatystoma vaillantii é um bagre de água doce que representa o recurso pesqueiro mais abundante no estuário amazônico. O arrasto da piramutaba é feito em escala industrial, caracterizado pela presença de muitas espécies de água doce e marinha capturadas de forma incidental, com e sem valor comercial. Aqui descrevemos a captura incidental da pesca industrial de piramutaba no estuário amazônico e avaliamos a relação de dois fatores ambientais, profundidade e salinidade, com a captura incidental de espécies de água doce e marinhas nas estações chuvosa e seca. Identificamos 21 espécies de peixes cartilaginosos (19,1% de água doce e 80,9% marinhos) e 125 espécies de peixes ósseos (25,6% de água doce e 74,4% marinhos). A captura incidental incluiu 64 espécies sem valor comercial (43% de todas as espécies capturadas) que sempre são descartadas. Os peixes de água doce e estuarinos exibiram abundâncias significativamente maiores em ambientes mais rasos, enquanto os peixes marinhos foram igualmente abundantes ao longo de todo o gradiente de profundidade. Inversamente, a abundância de peixes de água doce diminuiu significativamente, e a de peixes estuarinos e marinhos aumentou significativamente em salinidades maiores. Em relação ao estado de conservação das espécies capturadas, uma é reconhecida como vulnerável (VU) e sete como criticamente ameaçadas (CR). As informações sobre a captura incidental da pesca da piramutaba no estuário amazônico são fundaentais para subsidiar políticas pesqueiras regionais e gestão de áreas protegidas.

https://doi.org/10.1590/1809-4392202200342

13.

Impact of hepatitis C virus eradication with direct-acting antivirals on glycidic metabolism
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Sparvoli, Jucéli Márcia Hendges

; Sparvoli, Antonio Cardoso

; Dumith, Samuel de Carvalho

; Pereira, Afonso Alexandre

; Paula, Ana Luisa Machado de

; Garcia, Laís

; Belarmino, Vanusa

; Hora, Vanusa Pousada da

; Martínez, Ana Maria Barral de

; Gonçalves, Carla Vitola

Archives of Endocrinology and Metabolism

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jun 2023, Volume 67 N. 3 Pages 314 - 322

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To compare the glucose metabolism of patients with chronic hepatitis C virus infection treated with direct-acting antivirals (DAAs) in pretreatment and sustained viral response (SVR) periods. Materials and methods: This was an intervention pre-post study of 273 patients with chronic hepatitis C virus infection treated with DAAs from March 2018 to December 2019. Glycidic metabolism was evaluated through homeostasis model assessment (HOMA) – insulin resistance (IR) and HOMA-β indices and assessments of insulinemia and HbA1c levels. These parameters were analyzed with a T test by paired comparison of the means of the variables and Wilcoxon's test paired for the median; in the variables with an abnormal distribution, the Z score was generated for the mean in both the pretreatment and SVR periods. Statistical significance was considered at p ≤ 0.05. Results: Among 273 participants, 125 (45.8%) had prediabetes, and 50 (18.3%) had diabetes. In SVR, there was a significant increase in platelets, albumin, alkaline phosphatase, cholesterol and triglycerides and a significant decrease in aspartate aminotransferase, alanine aminotransferase, gamma GT and bilirubin. The HOMA-IR and HOMA-β indices increased in SVR from 1.95 to 2.29 (p = 0.087) and 71.20 to 82.60 (p = 0.001), respectively. Insulinemia increased from 7.60 μU/mL to 8.90 μU/mL (p = 0.011). HbA1c decreased from 5.6 to 5.4 (p < 0.001). Among patients with prediabetes and those with diabetes, the reduction in HbA1c values was significant (p = 0.006 and p = 0.026, respectively). Conclusion: SVR significantly impacts and leads to improvement in glucose metabolism in patients with chronic liver disease induced by hepatitis C virus.

https://doi.org/10.20945/2359-3997000000543

14.

Desenvolvimento do Pensamento Crítico: Questões de Género no Contexto da Formação em Artes no Ensino Superior
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Silva, Ana Maria Garcia Nolasco da

; Bárrios, Jorge Manuel Garrido

; Santos, Kátia Couto de Sá Sabino dos

Convergências - Revista de Investigação e Ensino das Artes

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may 2023, Volume 16 N. 31 Pages 85 - 96

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study aims to analyze the development of critical thinking on gender issues in the context of higher education training, taking as a case study the work proposal "Gender(s)" which aimed to carry out a transdisciplinary project articulated between the Curricular Units of Workshop of Arts, Technologies and Multimedia IV (OATM IV) - Sculpture and Multimedia Art modules - and Art Theory, of the 2nd semester of the academic year 2019/2020, promoting reflection on the issue of Gender and critical thinking of undergraduate students in Visual Arts and Technologies of the School of Education of the Polytechnic of Lisbon. The aim of this project is to promote reflection on the gender issue and critical thinking among undergraduate Visual Arts and Technologies students at the School of Education of the Polytechnic of Lisbon.During the process, teachers assumed the role of facilitators, creating a space free of censorship, finding that students mobilized and developed critical thinking, in processes of investigation and artistic creation around gender stereotypes. The imagination of different gender possibilities led to a reflection about values as cultural constructions and to the awareness of each one's agency to reinvent them and contribute to social change. In this way, we consider that artistic production and/or interpretation of art works stimulate autonomous thinking, capable of dealing with new situations, through the projection of several alternative hypotheses. We conclude, therefore, that art education is a privileged space to stimulate the development of critical thinking, without resorting to preconceived ideas, being, therefore, potentially able to combat class, culture or gender stereotypes and, in this way, contribute to the creation of values that guide a socially fair action.

Resumo Este artigo pretende analisar o desenvolvimento do pensamento crítico sobre questões de género no contexto da formação no ensino superior, tomando como caso de estudo a proposta "Género(s)", que visou a realização de um projeto transdisciplinar articulado entre as Unidades Curriculares de Oficina de Artes, Tecnologias e Multimédia IV (OATM IV) - módulos de Escultura e Arte Multimédia - e de Teoria da Arte, do 2º semestre do ano letivo de 2019/2020, promovendo a reflexão sobre a questão de género e o pensamento crítico dos estudantes de Licenciatura em Artes Visuais e Tecnologias da Escola Superior de Educação do Politécnico de Lisboa. No decorrer do processo, os professores assumiram um papel de facilitadores, criando um espaço livre de censura e constatando que os estudantes mobilizaram e desenvolveram o pensamento crítico em processos de investigação e criação artística em torno de estereótipos sobre questões de género. A imaginação de diferentes possibilidades de géneros levou a uma reflexão sobre os valores enquanto construções culturais e à consciência do agenciamento de cada um para os reinventar e contribuir para a mudança social. Deste modo, consideramos que a produção artística e/ou a interpretação de obras de arte estimulam o pensamento autónomo, capaz de lidar com situações novas, através da projeção de várias hipóteses alternativas. Concluímos, assim, que a educação artística é um espaço privilegiado para estimular o desenvolvimento do pensamento crítico, sem recorrer a ideias pré-concebidas, sendo por isso potencialmente apto a combater os estereótipos de classe, cultura ou género e, deste modo, contribuir para a criação de valores orientadores de uma ação socialmente justa.

https://doi.org/10.53681/c1514225187514391s.31.177

15.

Improving the quality of publications and advancing the paradigms of clinical and social pharmacy practice research: the Granada Statements
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Fernandez-Llimos, Fernando

; Desselle, Shane

; Stewart, Derek

; Garcia-Cardenas, Victoria

; Babar, Zaheer-Ud-Din

; Bond, Christine

; Dago, Ana

; Jacobsen, Ramune

; Nørgaard, Lotte Stig

; Polidori, Carlo

; Sánchez-Polo, Manuel

; Santos-Ramos, Bernardo

; Shcherbakova, Natalia

; Tonin, Fernanda S

Pharmaceutical Care España

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apr 2023, Volume 25 N. 2 Pages 65 - 99

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La farmacia y las ciencias farmacéuticas abarcan una serie de disciplinas diferentes. La farmacia práctica se ha definido como "la disciplina científica que estudia los diferentes aspectos de la práctica de la farmacia y su impacto en los sistemas sanitarios, el uso de los medicamentos y la atención al paciente". Así pues, los estudios sobre la farmacia práctica abarcan tanto elementos de farmacia clínica como de farmacia social. Como cualquier otra disciplina científica, la farmacia práctica clínica y social difunde los resultados de la investigación mediante revistas científicas. Los editores de revistas de farmacia clínica y farmacia social tienen un papel en la promoción de la disciplina mediante la mejora de la calidad de los artículos publicados. Al igual que ha ocurrido en otras áreas sanitarias (medicina y enfermería), un grupo de editores de revistas de farmacia práctica clínica y social se reunió en Granada, España, para debatir cómo las revistas podrían contribuir a fortalecer la farmacia práctica como disciplina. El resultado de esa reunión se recogió en esta Declaración de Granada, que comprende 18 recomendaciones agrupadas en seis temas: el uso adecuado de la terminología, los resúmenes con impacto, las revisiones por pares requeridas, la dispersión de revistas, un uso más eficaz y prudente de los indicadores bibliométricos de revistas y artículos, y la selección por parte de los autores de la revista de farmacia práctica más adecuada para presentar sus trabajos.

Abstract Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as “the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care”. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other health care areas (i.e., medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into six topics: the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics, and authors’ selection of the most appropriate pharmacy practice journal to submit their work.

https://doi.org/10.60103/phc.v25i2.816

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