RESUMO Objetivo: analisar, na literatura, o conhecimento, as atitudes e as práticas de enfermeiros sobre hepatite B. Método: revisão integrativa, com busca e seleção realizadas por pares e de forma independente, após consulta eletrônica às bases de dados CINAHL, MEDLINE, SCOPUS, Web of Science, LILACS, BDENF e IBECS em janeiro de 2021. A amostra foi constituída por 15 estudos primários publicados sem restrição temporal ou de idioma. A análise e a síntese dos resultados ocorreram de forma descritiva. Resultados: foram identificadas limitações no conhecimento, atitudes inconsistentes e práticas assistenciais comumente negligenciadas, relacionadas às medidas de prevenção, imunização e biossegurança, ao gerenciamento de risco e monitoramento de sintomas e complicações, que contribuíram para uma maior exposição ocupacional. Dentre os fatores associados, destacaram-se a baixa participação em atividades de educação permanente, o nível de formação, as condições laborais, as limitações na disponibilização de testes de imunização (anti-HBs) e a subnotificação de agravos. Conclusão: o conhecimento, as atitudes e as práticas desenvolvidos por enfermeiros, relacionados à hepatite B, mostraram-se limitados e inconsistentes, podendo resultar na maior exposição ocupacional, assim como impactar diretamente a cobertura vacinal e a ocorrência de incidentes.

ABSTRACT Objective: to analyze, in the literature, the nurses' knowledge, attitudes and practices regarding Hepatitis B. Method: an integrative review, with search and selection conducted independently by peers, after electronic queries in the CINAHL, MEDLINE, SCOPUS, Web of Science, LILACS, BDENF and IBECS databases in January 2021. The sample consisted in 15 primary studies published with no time or language restrictions. Analysis and synthesis of the results were carried out in a descriptive manner. Results: limitations in knowledge, inconsistent attitudes and commonly neglected assistance-related practices were identified, related to prevention, immunization and biosafety measures, to risk management and to monitoring of symptoms and complications, which contributed to greater occupational exposure. Among the associated factors, low participation in permanent education activities, training level, working conditions, limitations in the availability of immunization tests (anti-HBs) and underreporting of health problems stood out. Conclusion: the knowledge, attitudes and practices developed by nurses in relation to Hepatitis B proved to be limited and inconsistent, which may result in greater occupational exposure, as well as exert a direct impact on vaccination coverage and occurrence of incidents.

RESUMEN Objetivo: analizar, en la literatura, los conocimientos, las actitudes y las prácticas de los enfermeros en relación a la Hepatitis B. Método: revisión integradora, en la cual la búsqueda y la selección fueron realizadas por pares y de manera independiente, luego de consultas electrónicas en las siguientes bases de datos: CINAHL, MEDLINE, SCOPUS, Web of Science, LILACS, BDENF e IBECS en enero de 2021. La muestra estuvo compuesta por 15 estudios primarios publicados sin restricciones de tiempo o de idioma. El análisis y la síntesis de los resultados se realizaron en forma descriptiva. Resultados: se identificaron limitaciones en el conocimiento, actitudes inconsistentes y prácticas asistenciales comúnmente desatendidas, relacionadas con las medidas de prevención, inmunización y bioseguridad, y con la administración del riesgo y el monitoreo de síntomas y complicaciones, que contribuyeron a una mayor exposición ocupacional. Entre los factores asociados, se destacaron los siguientes: escasa participación en actividades de educación permanente, el nivel de formación, las condiciones laborales, las limitaciones en la disponibilidad de pruebas de inmunización (anti-HBs) y la subnotificación de problemas de salud. Conclusión: los conocimientos, las actitudes y las prácticas desarrolladas por los enfermeros, en relación con la Hepatitis B, demostraron ser limitados e inconsistentes, con la posibilidad de derivar en una mayor exposición ocupacional, al igual que de afectar directamente la cobertura de las vacunas y la frecuencia de incidentes.

SUMMARY OBJECTIVE: The objective of this study was to investigate the reliability and construct validity of the Self-Estimated Functional Inability because of Pain questionnaire for workers in a sample of Brazilian workers with musculoskeletal pain. METHODS: This is a questionnaire validation study. Workers with musculoskeletal pain were included. Besides the Self-Estimated Functional Inability because of Pain questionnaire for workers, we used the following instruments to perform construct validity: the Work Ability Index and the Numerical Pain Rating Scale. A subsample answered the Self-Estimated Functional Inability because of Pain questionnaire for workers in two moments to calculate reliability by means of the intraclass correlation coefficient and internal consistency by means of the Cronbach’s alpha. RESULTS: A total of 190 Brazilian workers were included. Regarding the construct validity, we observed a correlation with magnitude above 0.50 between the Self-Estimated Functional Inability because of Pain questionnaire for workers and the Numerical Pain Rating Scale, given that these two instruments have similarity in the construct, and correlations above 0.30 between the Self-Estimated Functional Inability because of Pain questionnaire for workers and the domains 2, 3, and 4 of the Work Ability Index. Regarding reliability, we observed adequate reliability (intraclass correlation coefficient=0.864) and internal consistency (Cronbach’s alpha=0.807). CONCLUSION: The Self-Estimated Functional Inability because of Pain questionnaire for workers is a reliable and valid instrument to be used in Brazilian workers with musculoskeletal pain.

Abstract Objective The aim of this study was to evaluate whether probiotics multi-strain formula affects the development of apical periodontitis (AP) induced in rats. Methodology 16 Wistar rats were divided in two groups (n=8): rats with AP fed with regular diet (Control-C (CG)); rats with AP, fed with regular diet and supplemented with multi-strain formula (one billion colony-forming units (CFU)): GNC Probiotic Complex (PCG) ( Lactobacillus acidophilus, Lactobacillus salivaris, Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium bifidum, Bifidobacterium animalis subs. lactis and Streptococcus thermofilus ). AP was induced in the upper and lower first molars by dental pulp exposure to the oral environment. PCG was administered orally through gavage for 30 days during the AP development. After this period the animals were euthanized and the mandibles were removed and processed for histologic analysis, and immunochemical assays for interleukin (IL)-6, IL-10, IL-1β, RANKL, OPG, and TRAP. The Mann–Whitney U test and Student’s t test were performed (P<.05). Results The CG showed more intense inflammatory infiltrate than the PCG group (P<.05). IL-1β, IL 6 and RANKL decreased in the PCG group compared with CG (P<.05). The IL-10 level increased in the PCG group (P<.05). The OPG level was similar in both groups (P>.05). The number of mature osteoclasts (TRAP-positive multinucleated cells) was lower in PCG group when compared to the CG (P<.05). Conclusion Probiotic Complex modulates inflammation and bone resorption in apical periodontitis.

Resumo O monitoramento dos parâmetros biofísicos de uma determinada região é de suma importância para sua população, tendo em vista os impactos causados por fenômenos climáticos de grande escala e a sazonalidade dos sistemas meteorológicos que afetam a região. Portanto, o objetivo do estudo é analisar a sazonalidade dos parâmetros biofísicos índice de Vegetação por Diferença Normalizada (IVDN) e temperatura da superfície terrestre (TST) assim como, sua interação com a chuva no Estado de Alagoas para os anos de 2001 e 2016 sobe influência de La Niña. Foram utilizados produtos de IVDN e TST do sensor MODIS, satélite TERRA, processados através do software Qgis 2.18.3. Inicialmente, foram realizados cálculos com os fatores de ajuste nas imagens de IVDN e TST, e posteriormente foram elaborados os mapas temáticos. Os resultados obtidos mostram um aumento no último trimestre do ano de 2016 nas classes de vegetação rala e solo exposto e uma diminuição da vegetação densa em relação ao ano de 2001, nas demais classes houve uma variabilidade sazonal da cobertura vegetal. Os mapas de TST apresentam correlação forte com o IVDN, mostrando uma relação inversamente proporcional entre os parâmetros. Na precipitação verificou-se a sua influência direta na resposta do IVDN e TST, devido ao tipo de vegetação encontrado na região.

Abstract The monitoring of the biophysical parameters of a given region is of paramount importance for its population, in view of the impacts caused by large-scale climatic factors and the seasonality of the meteorological systems that affect the region. Therefore, the objective of the study is analyzing the seasonality of the biophysical parameters Index of Vegetation by Normalized Difference (IVDN) and Land surface temperature (LST) as well, TST interaction with rainfall in the State of Alagoas for the years 2001 and 2016 rises under the influence of La Niña. IVDN and TST product TST from the MODIS sensor, TERRA satellite, were processed using the Qgis 2.18.3 software. Initially, calculations were performed with the adjustment factors in the IVDN and TST images, and later the thematic maps were prepared for the analyzes. The result TST obtained show an increase in the last quarter of 2016 in the classes of thin vegetation and exposed soil and a decrease in dense vegetation compared to 2001, in the other classes there is a seasonal variability of the vegetation cover. TST maps have direct influence with IVDN, showing an inversely proportional relationship between the parameters. In precipitation, TST direct influence on the response of IVDN and TST was verified, due to the type of vegetation found in the region.

Resumo O objetivo deste trabalho foi avaliar a eficiência do uso de Redes Neurais Artificiais (RNA) para a classificação de uso do solo da Bacia Hidrográfica do Rio Japaratuba - SE, a partir de uma imagem de sensoriamento remoto. Uma classificação pelo método Máxima Verossimilhança foi realizada para ser comparada com as classificações geradas por RNA, uma vez que o primeiro método já é consolidado na literatura. Para avaliar a eficiência das classificações foram analisados o índice Kappa, Exatidão Global e Raiz do Erro Médio Quadrático (REMQ). A classificação por Máxima Verossimilhança obteve índice Kappa de 0,95 e Exatidão Global de 96,43%. A RNA cuja arquitetura se mostrou mais eficiente obteve índice Kappa de 0,93, Exatidão Global de 94,14% e REMQ oscilando entre 0,35 e 0,45 durante suas 10000 iterações, sendo o valor estipulado como ótimo igual a 0,10. As RNA se mostraram eficientes na classificação de uso de solo a partir de imagens de sensoriamento remoto, tendo em vista que os resultados dos parâmetros de acurácia apresentaram valores que indicam uma concordância quase perfeita na classificação realizada por seis das oito arquiteturas de RNA testadas. Dessa forma os produtos gerados podem ser utilizados como ferramenta técnico-gerencial para a gestão ambiental da área de estudo.

Abstract The objective of this work was to evaluate the efficiency of the use of Artificial Neural Networks (ANN) for the classification of land use of the Japaratuba River Basin - SE, from a remote sensing image. A classification by the Maximum Likelihood method was performed to be compared with the classifications generated by ANN, since the first method is already consolidated in the literature. To assess the classifications efficiency, the Kappa Index, Global Accuracy and Root Mean Square Error (RMSE) were analyzed. The Maximum Likelihood classification obtained Kappa Index of 0.95 and Global Accuracy of 96.43%. The ANN architecture more efficient obtained a Kappa Index of 0.93, Global Accuracy of 94.14% and RMSE oscillating between 0.35 and 0.45 during its 10,000 iterations, while the value stipulated as excellent was 0.10. The ANN proved to be efficient in the classification of land use from remote sensing images, since the results of the accuracy parameters showed values that indicate an almost perfect agreement in the classification performed by six of the eight ANN's architectures tested. Thus the generated products can be used as a technical-managerial tool for the environmental management of the study area.

Abstract Background: Psoriatic Arthritis is the spondyloarthritis associated with psoriasis, which is often related to high mortality due to cardiovascular causes. Objectives: To quantify cardiovascular risk factors (hypertension, diabetes, dyslipidemia, obesity and smoking) and to measure risk by the Global Cardiovascular Risk Score in patients with psoriatic arthritis. Methods: Patients with psoriatic arthritis according to the Classification Criteria for Psoriatic Arthritis, aged between 30 and 74 years and without any other clinically manifest chronic inflammatory disease, atherosclerotic disease or heart failure were included. After an interview, clinical examination and data extraction from medical records, risk stratification was performed using a calculator available on the online platform of the Framingham Heart Study. We considered p < 0.05 as significant. Chi-square test and Fisher’s exact test were used to compare frequencies, as well as correlation measurements. Results: 45 patients were included, 68,9% of which were women and the mean age was 53,94 years. Dyslipidemia was confirmed in approximately 93%, hypertension in 46%, obesity in 40%, 33.3% were diabetics and, 13.3%, smokers; 95% had increased abdominal circumference. It was observed that 53% had high cardiovascular risk, 29% had intermediate risk and 18% had low risk. Individuals with altered C-reactive protein and erythrocyte sedimentation rate presented, respectively, higher levels of LDL-C and total cholesterol. Conclusions: There was a high occurrence of risk factors and the majority of the sample was stratified into high or intermediate cardiovascular risk.

Resumo O trabalho desenvolveu uma pesquisa por meio de questionários online com 55 professores de educação física da rede municipal de Fortaleza/CE, atuantes nas séries de 6° a 9° ano. Objetivou analisar o conhecimento e a aplicação das leis 10.639/03 e 11.645/08. Identificou-se que a maioria dos professores não sabe do que tratam as leis. Mesmo que os docentes não tenham conhecimento, trabalham a temática étnica na escola e afirmam que o conteúdo faz parte da disciplina. Conclui-se que é preciso remodelar as práticas pedagógicas, no que tange a temática, dar uma maior atenção à formação de professores para tal assunto, diante do desafio de construírem-se caminhos para o ensino.

Abstract The work developed a research through online questionnaires with 55 Physical Education teachers of the municipal network of Fortaleza/CE, acting in the grades 6 to 9. The objective was to analyze the knowledge and application of laws 10.639/03 and 11.645/08. It has been identified that most teachers do not know what the laws are about. Even teachers who are not aware of it, work on ethnic racial issues at school, and claim that content is part of the discipline. It is concluded that it is necessary to reshape the pedagogical practices, regarding the subject matter, giving greater attention to the training of teachers for this subject, facing the challenge of constructing new avenues for teaching.

Resumen El trabajo incluyó una encuesta mediante cuestionarios online a 55 profesores de educación física de la red municipal de Fortaleza/CE, que dan clase a los cursos de 6.° a 9.° año. El objetivo fue analizar el conocimiento y la aplicación de las leyes 10.639/03 y 11.645/08. Se identificó que la mayoría de los profesores no sabe de qué tratan las leyes. Incluso los docentes que no tienen conocimiento trabajan la temática étnico-racial en la escuela y afirman que el contenido forma parte de la disciplina. Se concluye que es necesario remodelar las prácticas pedagógicas en lo que se refiere a la temática y hacer mayor hincapié en la formación de profesores en ese tema ante el desafío de tender nuevas vías para la enseñanza.

ABSTRACT: Seedling production is an important step in the lettuce production system. However, there is a tendency to apply excessive irrigation at this stage. The aim of this study was to test the use of the Simplified Irrigation Controller (SIC) under two conditions: first, with the sensor installed in the substrate (measuring the soil water tension) and second, in the atmosphere (“atmospheric” - responding to vapor demand in the atmosphere) to control the irrigation of lettuce seedlings. The performance of the SIC was evaluated by monitoring plant traits. The lettuce seeds of the Regina cultivar were sown in styrofoam trays with commercial organic substrate. Both experiments were conducted under greenhouse conditions and evaluated under different SIC activation tensions. Shoot fresh weight and dry weight, height, number of leaves, leaf length, leaf area, water use efficiency (WUE) (ratio between the dry mass of plant produced by the volume of water applied), chlorophyll content, stomatal conductance and chlorophyll a fluorescence were assessed. In the experiment with the substrate sensor, the tension of 11.5 kPa caused death in 94 % of the seedlings and was disregarded in the statistical analysis. All biometric and physiological traits evaluated decreased as the SIC tensions increased. Thus, tensions of 4.0 (substrate sensor) and 3.5 kPa (atmospheric sensor) showed greater potential for producing vigorous seedlings, with WUE average values of 1.86 and 1.37 g L−1, respectively. Cultivation of lettuce seedlings proved viable under both conditions when the SIC was used, with the emergence of a number of practical advantages of the atmospheric sensor over the substrate one.

BACKGROUND Visceral Leishmaniasis (VL) is an infectious disease that is a significant cause of death among infants aged under 1 year and the elderly in Brazil. Serodiagnosis is a mainstay of VL elimination programs; however, it has significant limitations due to low accuracy. OBJECTIVE This study aimed to evaluate three recombinant Leishmania infantum proteins (rFc, rC9, and rA2) selected from previous proteomics and genomics analyses to develop enzyme-linked immunosorbent assay (ELISA) and immunochromatographic tests (ICT) for the serodiagnosis of human VL (HVL) and canine VL (CVL). METHODS A total of 186 human (70 L. infantum-infected symptomatic, 20 other disease-infected, and 96 healthy) and 185 canine (82 L. infantum-infected symptomatic, 27 L. infantum-infected asymptomatic, and 76 healthy) sera samples were used for antibody detection. FINDINGS Of the three proteins, rA2 (91.5% sensitivity and 87% specificity) and rC9 (95.7% sensitivity and 87.5% specificity) displayed the best performance in ELISA-HVL and ELISA-CVL, respectively. ICT-rA2 also displayed the best performance for HVL diagnosis (92.3% sensitivity and 88.0% specificity) and had high concordance with immunofluorescence antibody tests (IFAT), ELISA-rK39, IT-LEISH®, and ELISAEXT. ICT-rFc, ICT-rC9, and ICT-rA2 had sensitivities of 88.6%, 86.5%, and 87.0%, respectively, with specificity values of 84.0%, 92.0%, and 100%, respectively for CVL diagnosis. MAIN CONCLUSIONS The three antigens selected by us are promising candidates for VL diagnosis regardless of the test format, although the antigen combinations and test parameters may warrant further optimisation.

Objetivou-se por meio deste estudo avaliar as características estruturais, produtivas e o valor nutritivo do capim-Tifton 85 adubado com duas doses de nitrogênio em quatro idades de rebrota. Foi utilizado delineamento em blocos casualizados seguindo esquema fatorial 4 x 2, com 4 idades de rebrota (28, 35, 42 e 49 dias) e duas doses de nitrogênio (100 e 300 kg ha-1) com seis repetições, totalizando 48 unidades experimentais de 25 m² (5x5m) cada. O critério de blocagem foi à variação na área experimental. A produção de matéria seca incrementou linearmente, em média 56.4%, à medida que avançou a idade de rebrota de 28 para 49 dias (P<0,01). Entre as doses de N, houve aumento de 17.2% na produção de matéria seca quando adubado com 300 kg ha-1 de nitrogênio. A altura das plantas (P<0,01), assim como o número de folhas vivas (P<0,01), número de folhas expandidas (P<0,01) e o comprimento final da folha (P<0,01) aumentaram linearmente com o avanço da idade corte. A adubação do capim Tifton 85 com 100 kg ha-1 de N, manejado a cada 35 dias melhora a produção de matéria seca, características estruturais e valor nutricional da forragem para corte e/ou pastejo.

The objective of this study was to evaluate the structural, productive and nutritional value of Tifton 85 grass fertilized with two nitrogen doses at four regrowth ages. The experimental design was a randomized block in a factorial 4 x 2, with four regrowth ages (28, 35, 42 and 49 days) and two levels of nitrogen (100 and 300 kg ha-1) in six replicates, totaling 48 experimental units, of 25 m² (5x5m) each. The blocking criterion was the variation in the experimental area. Dry matter production increased linearly, on average 56.4%, as the regrowth age increased from 28 to 49 days (P<0.01). Among the N rates, there was a 17.2% increase in dry matter yield when fertilized with 300 kg / ha of nitrogen. The height of the plants (P <0.01), as well as the number of live leaves (P <0.01), number of expanded leaves (P <0.01) and the final leaf length (P <0.01) increased linearly with the advancement of cut age. Fertilization of Tifton 85 grass with 100 kg ha-1 of N, managed every 35 days improves the dry matter production, structural characteristics and nutritional value of forage for cutting and / or grazing.

RESUMO Objetivo: Comparar os resultados clínicos e escores funcionais do joelho em pacientes com altura patelar normal e patela alta submetidos a reconstrução isolada do ligamento patelofemoral medial. Métodos: Foram incluídos 37 joelhos de 33 pacientes com quadro de luxação recidivante da patela submetidos a reconstrução isolada do ligamento patelofemoral medial. Retrospectivamente, foi comparado o resultado clínico pós-operatório pelas escalas de Kujala e Lysholm entre o grupo de pacientes com altura patelar dentro da normalidade e aqueles com patela alta. Resultados: A amostra foi constituída por 37 pacientes; 16 joelhos de 14 pacientes pertenciam ao grupo da patela com altura normal e 21 joelhos de 19 pacientes compuseram o grupo com patela alta. No primeiro grupo, a pontuação média pela escala de Kujala foi de 85,8 e pela de Lysholm, 85,6. No segundo, a pontuação média pela escala de Kujala foi de 78,1 e pela de Lysholm, 79,7. Não foi observada diferença significativa entre os grupos em relação aos escores das escalas de Lysholm (p = 0,296) e de Kujala (p = 0,181). Conclusão: A reconstrução isolada do ligamento patelofemoral medial apresentou resultados semelhantes em pacientes com altura patelar normal e elevada.

ABSTRACT Objective: To compare the clinical outcomes and the results of knee functional scores in patients with normal patellar height and patella alta who underwent isolated medial patellofemoral ligament reconstruction. Methods: A total of 37 knees from 33 patients with recurrent patellar dislocation who underwent isolated medial patellofemoral ligament reconstruction were included. Retrospectively, the postoperative clinical results were compared using the Kujala and Lysholm scores in the group of patients with normal patellar height and in those with patella alta. Results: The sample consisted of 37 patients; 16 knees of 14 patients in the group with normal patellar height, 21 knees of 19 patients in the group with patella alta. In the first group, the mean Kujala score was 85.8 and the mean Lysholm score was 85.6. In the second, the mean Kujala score was 78.1 and the mean Lysholm score was 79.7. No significant differences were observed between the groups in relation to the Lysholm (p = 0.296) and Kujala scores (p = 0.181). Conclusion: Isolated medial patellofemoral ligament reconstruction presented similar results in patients with normal patellar height and patella alta.

RESUMO. Objetivou-se avaliar a produção, o valor nutritivo e a degradação ruminal potencial do feno de capim-Tifton 85 (Cynodon spp.) colhido em quatro idades de rebrota (28, 35, 42 e 49 dias) e adubado com duas doses de nitrogênio (N; 100 e 300 kg N ha-1). O delineamento foi o em blocos ao acaso, arranjado em esquema fatorial 4 x 2, com seis repetições. A área experimental foi o critério de blocagem. A adubação nitrogenada incrementou (p < 0,01) a produção de matéria seca e a produção de matéria seca digestível do feno e também os teores de lignina (p = 0,01) e proteína bruta (p = 0,01). Os teores de fibra em detergente neutro corrigida para cinzas e proteína (p = 0,01), fibra em detergente ácido (p = 0,01) e celulose (p = 0,02) ajustaram-se ao modelo quadrático de regressão em função das idades de rebrota. Para degradabilidade ruminal potencial do feno foi observado efeito quadrático (p = 0,01), com valor máximo de 73,1% aos 37 dias de rebrota. O feno de capim-Tifton 85 adubado com 300 kg ha-1 de N e colhido até os 37 dias de rebrota resulta em maior produção de matéria seca de feno, maiores teores de proteína bruta, melhor degradabilidade ruminal potencial da matéria seca.

ABSTRACT. The objective of this study was to evaluate the yield, nutritional value and potential ruminal degradation of Tifton 85 hay (Cynodon spp.) harvested at four regrowth ages (28, 35, 42 and 49 days) and fertilized with two nitrogen doses (N; 100 and 300 kg N ha-1). The experimental design was a randomized block design, arranged in a 4 x 2 factorial scheme, with six replications each. Nitrogen fertilization increased (p < 0.05) dry matter yield and digestible dry matter production of hay and also lignin and crude protein contents. Nitrogen fertilization increased (p < 0.01) the dry matter yield and the digestible dry matter production of hay, as well as lignin (p = 0.01) and crude protein (p = 0.01). The neutral detergent fiber corrected for ash and protein (p = 0.01), acid detergent fiber (p = 0.01) and cellulose (p = 0.02) adjusted to the quadratic function regression model of the regrowth ages. For potential rumen degradability hay, it was observed quadratic effect (p = 0.01) with maximum value of 73.1% at 37 days of regrowth. Tifton 85 hay fertilized with 300 kg ha -1 of N and harvested up to 37 days of regrowth results in higher hay dry matter yield, higher crude protein content, and better dry matter rumen degradability.

RESUMO. Foram realizados dois experimentos com objetivo de avaliar o efeito de diferentes doses de torta de mamona (0, 200 e 300 g m-2) e lâminas de irrigação (204, 224, 278 e 321 mm, em 2014 e 278, 302, 397 e 444 mm, em 2015) na produtividade e qualidade de bulbos de cebola, nos anos de 2014 e 2015. Nos experimentos o delineamento experimental foi em blocos casualizados (fatorial 4 x 3), com cinco repetições. O manejo da irrigação foi realizado pelo “Acionador simplificado de irrigação” (ASI), em resposta à tensão de água no solo, no tratamento de maior lâmina. Foram avaliadas a biomassa seca de planta (BSP) e de bulbo (BSP), a produtividade total (PT), o peso médio fresco de bulbo (PMFB), o peso médio seco de bulbo (PMSB), o diâmetro de médio dos bulbos (DMB), a eficiência de uso da água (EUA). As maiores lâminas de irrigação influenciaram positivamente a produção de bulbos de cebola, independente da dose de torta de mamona aplicada. As doses de torta de mamona influenciaram positivamente a produção de bulbos de cebola quando maiores lâminas de irrigação foram aplicadas. A EUA não foi influenciada pelas lâminas.

ABSTRACT. Two experiments were carried out to evaluate the effects that different doses of castor bean (0, 200, and 300 g m-2) and irrigation levels (204, 224, 278, and 321 mm in 2014, and 278, 302, 397, and 444 mm in 2015) have on both the productivity and quality of onion bulbs. In the experiments, the experimental design was randomized blocks (4 x 3 factorial scheme), with five replicates. Irrigation management was performed using a Simplified Irrigation Device (SID) in response to soil water tension in the treatment of highest irrigation depth. The following variables were evaluated: plant dry biomass (PDB), bulb dry biomass (BDB), total yield (TY), mean bulb fresh weight (MBFW), mean bulb dry weight (MBDW), mean bulb diameter (MBD) and water use efficiency (WUE). The highest irrigation depths positively influenced the mean production of onion bulbs, regardless of the applied dose of castor cake. The doses of castor cake positively influenced the production of onion bulbs when higher irrigation depths were applied.

RESUMO. Foram realizados dois experimentos com objetivo de avaliar o efeito da cinza (40, 80 e 120 g por planta), da torta de mamona (140 e 280 g por planta) e de lâminas de irrigação (135, 165, 191 e 213 mm) no crescimento e produção do tomateiro orgânico, cultivado em vaso e ambiente protegido. O delineamento experimental foi em blocos casualizados e o manejo da irrigação realizado pelo acionador automático para irrigação. Foram avaliadas a altura das plantas, os números de folhas, cachos, flores e frutos, as massas de fruto total, comercial e com podridão apical, e os diâmetros de fruto total e comercial. A maioria das variáveis de crescimento obtiveram ganhos com a aplicação de 140 g de cinza e 280 g de torta. A dose de 280 g de torta proporcionou maior massa fresca comercial (1,78 kg por planta), independente da dose de cinza. O déficit hídrico reduziu os valores da maioria das variáveis de crescimento e de produção. A lâmina de 213 mm foi a responsável pela maior massa fresca comercial (4,04 kg por planta). As maiores eficiências de uso de água, 37,00 e 37,93 kg m-3, foram encontradas para as lâminas de 191 e 213 mm, respectivamente.

ABSTRACT. Two experiments were performed to evaluate the effect of ash (40, 80, and 120 g per plant), castor cake (140 and 280 g per plant) and water depth (135, 165, 191, and 213 mm) on the growth and production of organic tomato cultivated in pots in a greenhouse. The experimental design was randomized blocks, and the irrigation was managed using an automatic irrigation device. The following variables were evaluated: plant heights, numbers of leaves, bunches, flowers and fruits, total mass of fruits, mass of marketable fruits, mass of fruits with blossom-end rot, total diameter of fruits, and diameter of marketable fruits. Most of the growth variables showed gains with the application of 140 g of ash and 280 g of cake. The dose of 280 g of castor cake was responsible for the greatest mass of marketable fruits (1.78 kg per plant), regardless of the ash dose. The water deficit reduced values of most of the variables of growth and production. The irrigation depth of 213 mm was responsible for the greatest mass of marketable fruits (4.04 kg per plant). The highest water use efficiencies, 37.00 and 37.93 kg m-3, were observed at irrigation depths of 191 and 213 mm, respectively.

Fundamento: A insuficiência cardíaca é uma complicação grave associada ao uso da doxorrubicina (DOX). O strain, avaliado por speckle tracking bidimensional (2D-STE), tem se mostrado útil na identificação de disfunção ventricular subclínica. Objetivos: a) Investigar o comportamento do strain na identificação de disfunção ventricular subclínica em pacientes que usaram DOX; b) investigar determinantes do comportamento do strain nestes pacientes. Métodos: Estudo transversal com 81 participantes: 40 pacientes que usaram DOX ± 2 anos antes do estudo e 41 controles. Todos tinham fração de ejeção do ventrículo esquerdo (FEVE) ≥ 55%. A dose total de DOX foi de 396 mg (242 mg/m2). A função sistólica do VE foi avaliada pela FEVE (Simpson), assim como pelo strain longitudinal (εLL), circunferencial (εCC) e radial (εRR). Realizamos análise de regressão linear multivariada (RLM) usando como variáveis dependentes o εLL (modelo 1) e o εCC (modelo 2). Resultados: Os valores da pressão arterial sistólica e diastólica foram maiores no grupo controle (p < 0,05). O εLL foi menor no grupo DOX (-12,4 ± 2,6%) versus controle (-13,4 ± 1,7%; p = 0,044). O mesmo ocorreu em relação ao εCC: -12,1 ± 2,7% (DOX) versus -16,7 ± 3,6% (controles; p < 0,001). A onda S' foi menor no grupo DOX (p = 0,035). Na RLM, a DOX foi preditora independente de redução do εCC (B = -4,429, p < 0,001). DOX (B = -1,289, p = 0,012) e idade (B = -0,057, p = 0,029) foram marcadores independentes de redução do εLL. Conclusões: a) O εLL, o εCC e a onda S' estão reduzidos nos pacientes que usaram DOX ±2 anos antes do estudo, apesar da FEVE ser normal, sugerindo presença de disfunção ventricular subclínica; b) a DOX foi preditora independente de redução do εCC; c) o uso prévio da DOX e a idade foram marcadores independentes de redução do εLL.

Background: Heart failure is a severe complication associated with doxorubicin (DOX) use. Strain, assessed by two-dimensional speckle tracking (2D-STE), has been shown to be useful in identifying subclinical ventricular dysfunction. Objectives: a) To investigate the role of strain in the identification of subclinical ventricular dysfunction in patients who used DOX; b) to investigate determinants of strain response in these patients. Methods: Cross-sectional study with 81 participants: 40 patients who used DOX ±2 years before the study and 41 controls. All participants had left ventricular ejection fraction (LVEF) ≥55%. Total dose of DOX was 396mg (242mg/ms2). The systolic function of the LV was evaluated by LVEF (Simpson), as well as by longitudinal (εLL), circumferential (εCC), and radial (εRR) strains. Multivariate linear regression (MLR) analysis was performed using εLL (model 1) and εCC (model 2) as dependent variables. Results: Systolic and diastolic blood pressure values were higher in the control group (p < 0.05). εLL was lower in the DOX group (-12.4 ±2.6%) versus controls (-13.4 ± 1.7%; p = 0.044). The same occurred with εCC: -12.1 ± 2.7% (DOX) versus -16.7 ± 3.6% (controls; p < 0.001). The S’ wave was shorter in the DOX group (p = 0.035). On MLR, DOX was an independent predictor of reduced εCC (B = -4.429, p < 0.001). DOX (B = -1.289, p = 0.012) and age (B = -0.057, p = 0.029) were independent markers of reduced εLL. Conclusion: a) εLL, εCC and the S’ wave are reduced in patients who used DOX ±2 years prior to the study despite normal LVEF, suggesting the presence of subclinical ventricular dysfunction; b) DOX was an independent predictor of reduced εCC; c) prior use of DOX and age were independent markers of reduced εLL.