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Geometria orofaríngea e parâmetros acústicos vocais de indivíduos hígidos e com doença de Parkinson
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Silva, Joice Maely Souza da

; Gomes, Adriana de Oliveira Camargo

; Coriolano, Maria das Graças Wanderley de Sales

; Teixeira, Julianne Pitanga

; Lima, Hellen Vasconcelos Silva Leal de

; Paulino, Clarissa Evelyn Bandeira

; Silva, Hilton Justino da

; Lira, Zulina Souza de

CoDAS

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2023, Volume 35 N. 2 elocation e20210304

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose to verify whether there are differences in acoustic measures and oropharyngeal geometry between healthy individuals and people with Parkinson's disease, according to age and sex, and to investigate whether there are correlations between oropharyngeal geometry measures in this population. Methods 40 individuals participated, 20 with a diagnosis of Parkinson's disease and 20 healthy individuals, matched by age, sex, and body mass index. Acoustic variables included fundamental frequency, jitter, shimmer, glottal-to-noise excitation ratio, noise, and mean intensity. Oropharyngeal geometry variables were measured with acoustic pharyngometry. Results geometry variables were smaller in the group with Parkinson's disease, and older adults with Parkinson's disease had a smaller oropharyngeal junction area than healthy older adults. Regarding acoustic parameters of voice, fundamental frequency values were lower in males with Parkinson's disease, and jitter values were higher in the non-elderly subjects with Parkinson's disease. There was a moderate positive correlation between oral cavity length and volume, pharyngeal cavity length and vocal tract length, and pharyngeal cavity volume and vocal tract volume. Conclusion individuals with Parkinson's disease had smaller glottal areas and oropharyngeal junction areas than healthy individuals. When distributed into sex and age groups, the fundamental frequency was lower in males with Parkinson's disease. There was a moderate positive correlation between oropharyngeal length and volume measures in the study sample.

RESUMO Objetivo verificar se existem diferenças nas medidas acústicas e da geometria orofaríngea entre indivíduos hígidos e pessoas com Doença de Parkinson, segundo a idade e sexo e investigar se há correlações entre as medidas geométricas orofaríngeas nessa população. Método participaram 40 indivíduos, sendo 20 com diagnóstico de Doença de Parkinson e 20 indivíduos hígidos, pareados por faixa etária, sexo e índice de massa corporal. As variáveis acústicas estudadas foram frequência fundamental, jitter, shimmer, glottal-to-noise excitation ratio, ruído e média da intensidade. As variáveis geométricas da orofaringe foram aferidas por faringometria acústica. Resultados as variáveis geométricas foram menores no grupo com Doença de Parkinson e os idosos com Doença de Parkinson apresentaram menor área da junção orofaríngea que os idosos hígidos. Com relação aos parâmetros acústicos vocais, o valor da frequência fundamental foi menor no sexo masculino, no grupo com Doença de Parkinson e os valores de jitter foram maiores no grupo não idoso dos sujeitos com Doença de Parkinson. Houve correlação positiva moderada entre o comprimento e volume da cavidade oral, comprimento da cavidade faríngea e o comprimento do trato vocal e do volume da cavidade faríngea e o volume do trato vocal. Conclusão indivíduos com Doença de Parkinson apresentaram menores valores de área glótica e área da junção orofaríngea, comparativamente aos hígidos. Quando distribuídos por faixa etária e sexo, a frequência fundamental foi menor no grupo com doença de Parkinson, na população masculina. Houve correlação positiva moderada entre as medidas de comprimento e volume da orofaringe, na amostra estudada.

https://doi.org/10.1590/2317-1782/20232021304pt

Non-pharmacological methods for pain relief during mammography: integrative review
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Santos, Katherine Olga Correia Alves

; Franco, Clarissa Lima

; Ribeiro, Caique Jordan Nunes

; Nunes, Mariangela da Silva

; Oliveira, Maria do Carmo de

BrJP

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jun 2022, Volume 5 N. 2 Pages 143 - 146

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO JUSTIFICATIVA E OBJETIVOS A mamografia é um exame de imagens das mamas, obtidas por meio de radiografia com realização da compressão do tecido mamário. A dor é um fator constantemente relatado pelas pacientes submetidas ao procedimento e, por esse motivo, evidencia-se a necessidade de estabelecer estratégias alternativas não farmacológicas que reduzam a sensação dolorosa. O objetivo deste estudo foi realizar uma revisão integrativa sobre os métodos não farmacológicos utilizados para o alívio da dor durante o exame mamográfico. CONTEÚDO A busca foi realizada no mês de abril de 2021 em quatro bases de dados (Pubmed, Medline, Scopus e CINAHL) utilizando os descritores “dor”, “manejo da dor”, “mamografia”, “musicoterapia” e “terapias complementares”. Após a leitura e análise final, quatro artigos atenderam aos critérios preestabelecidos, abordando o manejo não farmacológico da dor durante a mamografia. Os estudos evidenciaram diferentes métodos para redução da dor, como a utilização de almofada e a alteração no protocolo de compressão, bem como a intervenção com música. CONCLUSÃO Evidências sobre o manejo não farmacológico da dor relacionada à mamografia ainda são escassas. Entre as estratégias encontradas, o protocolo personalizado de compressão e o uso de almofadas compressíveis apresentaram eficácia analgésica, enquanto o uso da música não resultou em redução significativa da dor procedimental. No entanto, por se tratar de uma revisão integrativa, destaca-se a necessidade da realização de sínteses de evidências com maior rigor metodológico para estimar o tamanho do efeito analgésico dessas intervenções.

ABSTRACT BACKGROUND AND OBJECTIVES Mammography is an examination of images of the breasts, obtained through radiography with compression of the breast tissue. Pain is a factor constantly reported by patients undergoing the procedure and, for this reason, there is a need to establish alternative non-pharmacological strategies that reduce the sensation of pain. The aim of this study was to carry out an integrative review on non-pharmacological methods used for pain relief during mammography examination. CONTENTS The search was carried out in April 2021 in four databases (Pubmed, Medline, Scopus and CINAHL) using the descriptors “pain”, “pain management”, “mammography”, “music therapy” and “complementary therapies “. After reading and final analysis, four articles met the pre-established criteria, addressing the non-pharmacological management of pain during mammography. The studies showed different methods to reduce pain, such as the use of pads and changes in the compression protocol, as well as the intervention with music. CONCLUSION Evidence on the non-pharmacological management of mammography-related pain is still scarce. Among the strategies found, the customized compression protocol and the use of compressible pads showed analgesic efficacy, while the use of music did not result in a significant reduction in procedural pain. However, as this is an integrative review, there is a need to carry out evidence syntheses with greater methodological rigor to estimate the size of the analgesic effect of these interventions.

https://doi.org/10.5935/2595-0118.20220029-en

COVID-19 e os impactos na saúde mental: uma amostra do Rio Grande do Sul, Brasil
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Duarte, Michael de Quadros

; Santo, Manuela Almeida da Silva

; Lima, Carolina Palmeiro

; Giordani, Jaqueline Portella

; Trentini, Clarissa Marceli

Ciência & Saúde Coletiva

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sep 2020, Volume 25 N. 9 Pages 3401 - 3411

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As pandemias, como a da COVID-19, afetam uma quantidade relativamente grande de pessoas e impõem novas regras e hábitos sociais para a população mundial. As informações sobre a pandemia são constantes na mídia. Além disso, o distanciamento social foi adotado no Brasil como medida de prevenção da disseminação da COVID-19, o que pode ter consequências econômicas e psicossociais. Nesse contexto, o objetivo deste estudo foi verificar os fatores associados a indicadores de sintomas de transtornos mentais em residentes do Rio Grande do Sul, durante o período inicial da política de distanciamento social decorrente da pandemia da COVID-19. O estudo foi aprovado pelo CONEP. Participaram 799 pessoas, com idades entre 18 e 75 anos (M = 36,56; DP = 12,88), 82,7% mulheres, que responderam um questionário sociodemográfico, de distanciamento social e ao Self-Report Questionnaire (SRQ-20). Os resultados indicaram que ter renda diminuída no período, fazer parte do grupo de risco e estar mais exposto a informações sobre mortos e infectados, são fatores que podem provocar maior prejuízo na saúde mental nesse período pandemia. Investigar determinantes sociais que contribuem para maior vulnerabilidade ao adoecimento mental da população é importante no campo da saúde coletiva para o planejamento de ações e políticas públicas.

Abstract Pandemics such as that of COVID-19 affect a relatively large number of people and impose new rules and social habits on the world population. Information about the pandemic is constant in the media. Moreover, social distancing has been adopted in Brazil to prevent the spread of COVID-19, which may have economic and psychosocial consequences. This study aimed to verify the factors associated with indicators of mental disorders symptoms in residents of Rio Grande do Sul during the initial period of the social distancing policy. The study was approved by CONEP. There were 799 participants, aged between 18 and 75 years (M = 36.56; SD = 12.88); 82.7% were women, who answered a sociodemographic questionnaire of social distancing and the Self-Report Questionnaire (SRQ-20). The results indicated that having decreased income in the period, being part of the risk group and being more exposed to information about deaths and infected, are factors that can significantly harm mental health in this pandemic period. Investigating social determinants that contribute to greater vulnerability to the mental illness of the population is vital in the field of collective health for the planning of public actions and policies.

https://doi.org/10.1590/1413-81232020259.16472020 38034 downloads

[SciELO Preprints] - COVID-19 and the impacts on mental health: a sample from Rio Grande do Sul
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Duarte, Michael Quadros Santo, Manuela Almeida da Silva Lima, Carolina Palmeiro Giordani, Jaqueline Portella Trentini, Clarissa Marceli

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Publication date: 2020-05-17

Abstract: En Pt

Pandemics, such as COVID-19 affect a relatively large number of people and impose new rules and social habits for the whole population. Information about the pandemic are constant in the media. Social distancing was also initiated in Brazil as a measure to prevent the spread of the new coronavirus, which can have economic and psychosocial consequences. In this context, the objective of this paper was to verify the association between social distance, impact on family income and exposure to information, with indicators of symptoms of mental disorders in residents of the state of Rio Grande do Sul/Brazil during the COVID-19 pandemic. This study was approved by CONEP/BR. 799 people participated, 18 - 75 years old (M = 36.56; SD = 12.88), 82.7% women, who answered a sociodemographic and social distance questionnaire, and the Self-Report Questionnaire (SRQ -20). The results indicated that not being a health worker, having a reduced income in the period, being part of the risk group and being more exposed to information about dead and infected people, are factors that can cause greater damage to mental health in this pandemic period. These factors and their association with social distance are discussed.

As pandemias, como a de COVID-19, afetam uma quantidade relativamente grande de pessoas e impõem, pelo tempo que duram, novas regras e hábitos sociais para a população mundial. As informações sobre a pandemia são constantes na mídia. Além disso, o distanciamento social foi adotado também no Brasil como medida de prevenção da disseminação do novo coronavírus, o que pode ter consequências econômicas e psicossociais. Nesse contexto, o objetivo deste estudo foi verificar a associação entre o distanciamento social, impacto na renda familiar e exposição a informações com os indicadores de sintomas de transtornos mentais em residentes do estado do Rio Grande do Sul durante a pandemia de COVID-19. O estudo foi aprovado pelo CONEP. Participaram 799 pessoas, com idades entre 18 e 75 anos (M = 36,56; DP = 12,88), 82,7% mulheres, que responderam um questionário sociodemográfico e sobre o distanciamento social, além do Self-Report Questionnaire (SRQ-20). Os resultados indicaram que não ser trabalhador da saúde, ter renda diminuída no período, fazer parte do grupo de risco e estar mais exposto a informações sobre mortos e infectados, são fatores que podem provocar maior prejuízo na saúde mental nesse período pandemia. Discute-se esses fatores e sua associação ao distanciamento social.

https://doi.org/10.1590/SciELOPreprints.507

COVID-19 e os impactos na saúde mental: uma amostra do Rio Grande do Sul, Brasil
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Duarte, Michael de Quadros

; Santo, Manuela Almeida da Silva

; Lima, Carolina Palmeiro

; Giordani, Jaqueline Portella

; Trentini, Clarissa Marceli

Ciência & Saúde Coletiva

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2020, Volume 25 N. 9 Pages 3401 - 3411

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232020259.16472020

Comment on the study Coronary Artery Bypass Surgery in Brazil: Analysis of the National Reality Through the Bypass Registry that was presented at the 46th Congress of the Brazilian Society of Cardiovascular Surgery, Nova Lima, BH, Brazil, April 5 and 6, 2019
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Dallan, Luís Alberto O.

; Paez, Rodrigo Pereira

; Hossne Junior, Nelson Américo

; Santo, José Amalth do Espírito

; Berwanger, Otavio

; Santos, Renato Hideo Nakagawa

; Kalil, Renato Abdala Karam

; Jatene, Fabio B.

; Cavalcanti, Alexandre Biasi

; Zilli, Alexandre Cabral

; Bettiati Jr, Luiz Carlos

; Figueira, Fernando Augusto Marinho dos Santos

; D’Azevedo, Stephanie Steremberg Pires

; Soares, Marcelo José Ferreira

; Fernandes, Marcio Pimentel

; Ardito, Roberto Vito

; Bogdan, Renata Andrea Barberio

; Campagnucci, Valquíria Pelisser

; Nakasako, Diana

; Rodrigues, Clarissa Garcia

; Rodrigues Junior, Anilton Bezerra

; Cascudo, Marcelo Matos

; Atik, Fernando Antibas

; Lima, Elson Borges

; Nina, Vinicius José da Silva

; Heluy, Renato Albuquerque

; Azeredo, Lisandro Gonçalves

; Henrique Junior, Odilon Silva

; Mendonça, José Teles de

; Silva, Katharina Kelly de Oliveira Gama

; Pandolfo, Marcelo

; Lima Júnior, José Dantas de

; Faria, Renato Max

; Santos, Jonas Gonçalves dos

; Coelho, Guilherme Henrique Biachi

; Pereira, Sergio Nunes

; Senger, Roberta

; Buffolo, Enio

; Caputi, Guido Marco

; Oliveira, Juliana Aparecida Borges de

; Gomes, Walter J.

Brazilian Journal of Cardiovascular Surgery

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aug 2019, Volume 34 N. 4 Pages 504 - 506

Abstract: En | Text: En | PDF: En

https://doi.org/10.21470/1678-9741-2019-0606 335 downloads

Coronary Artery Bypass Surgery in Brazil: Analysis of the National Reality Through the BYPASS Registry
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Paez, Rodrigo Pereira

; Hossne Junior, Nelson Américo

; Santo, José Amalth do Espírito

; Berwanger, Otavio

; Santos, Renato Hideo Nakagawa

; Kalil, Renato Abdala Karam

; Jatene, Fabio B.

; Cavalcanti, Alexandre Biasi

; Zilli, Alexandre Cabral

; Bettiati Jr, Luiz Carlos

; Figueira, Fernando Augusto Marinho dos Santos

; D'Azevedo, Stephanie Steremberg Pires

; Soares, Marcelo José Ferreira

; Fernandes, Marcio Pimentel

; Ardito, Roberto Vito

; Bogdan, Renata Andrea Barberio

; Campagnucci, Valquíria Pelisser

; Nakasako, Diana

; Rodrigues, Clarissa Garcia

; Rodrigues Junior, Anilton Bezerra

; Cascudo, Marcelo Matos

; Atik, Fernando Antibas

; Lima, Elson Borges

; Nina, Vinicius José da Silva

; Heluy, Renato Albuquerque

; Azeredo, Lisandro Gonçalves

; Henrique Junior, Odilon Silva

; Mendonça, José Teles de

; Silva, Katharina Kelly de Oliveira Gama

; Pandolfo, Marcelo

; Lima Júnior, José Dantas de

; Faria, Renato Max

; Santos, Jonas Gonçalves dos

; Coelho, Guilherme Henrique Biachi

; Pereira, Sergio Nunes

; Senger, Roberta

; Buffolo, Enio

; Caputi, Guido Marco

; Oliveira, Juliana Aparecida Borges de

; Gomes, Walter J.

Brazilian Journal of Cardiovascular Surgery

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apr 2019, Volume 34 N. 2 Pages 142 - 148

Abstract: En | Text: En | PDF: En

Abstract Introduction: Coronary artery bypass grafting (CABG) is the most frequently performed heart surgery in Brazil. Recent international guidelines recommend that national societies establish a database on the practice and results of CABG. In anticipation of the recommendation, the BYPASS Registry was introduced in 2015. Objective: To analyze the profile, risk factors and outcomes of patients undergoing CABG in Brazil, as well as to examine the predominant surgical strategy, based on the data included in the BYPASS Registry. Methods: A cross-sectional study of 2292 patients undergoing CABG surgery and cataloged in the BYPASS Registry up to November 2018. Demographic data, clinical presentation, operative variables, and postoperative hospital outcomes were analyzed. Results: Patients referred to CABG in Brazil are predominantly male (71%), with prior myocardial infarction in 41.1% of cases, diabetes in 42.5%, and ejection fraction lower than 40% in 9.7%. The Heart Team indicated surgery in 32.9% of the cases. Most of the patients underwent cardiopulmonary bypass (87%), and cardioplegia was the strategy of myocardial protection chosen in 95.2% of the cases. The left internal thoracic artery was used as a graft in 91% of the cases; the right internal thoracic artery, in 5.6%; and the radial artery in 1.1%. The saphenous vein graft was used in 84.1% of the patients, being the only graft employed in 7.7% of the patients. The median number of coronary vessels treated was 3. Operative mortality was 2.8%, and the incidence of cerebrovascular accident was 1.2%. Conclusion: CABG data in Brazil provided by the BYPASS Registry analysis are representative of our national reality and practice. This database constitutes an important reference for indications and comparisons of therapeutic procedures, as well as to propose subsequent models to improve patient safety and the quality of surgical practice in the country.

https://doi.org/10.21470/1678-9741-2018-0313 1270 downloads

Effect of the treatment of Copaifera duckei oleoresin (copaiba) in streptozotocin-induced diabetic rats
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Carvalho, Helison Oliveira

; Santos, Igor Victor Ferreira dos

; Rocha, Clarice Flexa da

; Barros, Albenise Santana Alves

; Souza, Belmira Silva Faria e

; Ferreira, Irlon Maciel

; Bezerra, Roberto Messias

; Lima, Clarissa Silva

; Castro, Andres Navarrete

; Carvalho, José Carlos Tavares

Revista Brasileira de Farmacognosia

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dec 2018, Volume 28 N. 6 Pages 724 - 731

Abstract: En | Text: En | PDF: En

ABSTRACT Diabetes mellitus is a syndrome that reaches more than 382 million people worldwide. It interferes with the metabolism of carbohydrates, causing chronic hyperglycemia. The objective of this study was to evaluate the effect of the Copaifera duckei, Dwyer, Fabaceae, oleoresin on streptozotocin-induced (STZ) diabetic rats. This study was based on the induction of diabetes mellitus by streptozotocin (55 mg/kg, i.p.) in Wistar rats and treated with doses of C. duckei oleoresin (250 and 500 mg/kg, p.o.). Subsequently, the clinical, biochemical and histopathological of the pancreas parameters were evaluated. Gas chromatographic analysis indicated that β-bisabolene (22.29%), β-caryophyllene (21.25%) and α-farnesene (15.58%) sesquiterpenes were the major components of the C. duckei oleoresin. In streptozotocin-induced diabetes mellitus, it was possible to observe that the C. duckei oleoresin treatment had a significant effect (p < 0.001) on the clinical parameters, and that there was a positive improvement. This was attenuated by the urea, creatinine, and transaminases alterations (p < 0.001) observed in animals with diabetes mellitus, as well as the significantly reduced (p < 0.001) values of total cholesterol, triacylglycerides, and glucose. In the histopathological analyses of the pancreas, it was observed that the C. duckei oleoresin was able to restore β-cells and to significantly increase the quantity and diameter of the Langerhans islets (p < 0.05), when compared to the diabetic group. The treatment with C. duckei oleoresin, employed under the conditions of this study, presented antidiabetic activity and can improve the complications found in this syndrome.

https://doi.org/10.1016/j.bjp.2018.09.004 895 downloads

Blanca Susana Guevara Werlang (15/10/1955–15/11/2013): Um Pouco da História
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Trentini, Clarissa Marceli

; Sá, Samantha Dubugras

; Oliveira, Margareth da Silva

; Argimon, Irani Iracema de Lima

Psicologia: Ciência e Profissão

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2018, Volume 38 N. spe Pages 201 - 206

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: Este artigo tem como objetivo revisitar os feitos e homenagear a professora doutora Blanca Susana Guevara Werlang, cinco anos após seu falecimento. Trata-se de uma importante figura na área da avaliação psicológica e em assuntos ligados à prevenção do suicídio, cujo legado se colhe ainda nos tempos atuais. Sua expressiva e relevante produção abarca principalmente temas ligados ao desenvolvimento e adaptação de instrumentos de avaliação psicológica, nas áreas de intervenção clínica e comportamentos violentos. Blanca foi Bolsista Produtividade do CNPq, Professora Titular da Faculdade de Psicologia da Pontifícia Universidade Católica do Rio Grande do Sul e integrou a Comissão Consultiva em Avaliação Psicológica do Conselho Federal de Psicologia de 2005 até seu falecimento, no ano de 2013.

Abstract: This article aims to review the achievements and to honor Professor Blanca Susana Guevara Werlang, five years after her death. She was an important figure in the area of psychological evaluation and in matters related to suicide prevention, and her legacy is still current. Her expressive and relevant production covers topics related to the development of instruments of psychological evaluation and areas of clinical intervention and violent behavior. Blanca was Professor of Psychology at the Pontifícia Universidade Católica do Rio Grande do Sul and joined the Committee of Psychology of the Council of Psychology from 2005 until her death in 2013.

Resumen: Este artículo tiene como objetivo revisar los hechos y homenajear a la profesora doctora Blanca Susana Guevara Werlang, cinco años después de su fallecimiento. Se trata de una importante figura en el área de la evaluación psicológica y en asuntos relacionados a la prevención del suicidio, cuyo legado sigue siendo un tema actual. Su expresiva y relevante producción abarca principalmente temas vinculados al desarrollo y adaptación de instrumentos de evaluación psicológica, en las áreas de intervención clínica y comportamiento violento. Blanca fue Becaria de Productividad del CNPq, Profesora Titular de la Facultad de Psicología de la Pontifícia Universidad Católica de Rio Grande do Sul e integró la Comisión Consultiva en Evaluación Psicológica del Consejo de Psicología de 2005 hasta su fallecimiento en el año 2013.

https://doi.org/10.1590/1982-3703000211944 1530 downloads

10.

The Brazilian Registry of Adult Patient Undergoing Cardiovascular Surgery, the BYPASS Project: Results of the First 1,722 Patients
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Gomes, Walter J.

; Moreira, Rita Simone

; Zilli, Alexandre Cabral

; Bettiati Jr, Luiz Carlos

; Figueira, Fernando Augusto Marinho dos Santos

; D' Azevedo, Stephanie Steremberg Pires

; Soares, Marcelo José Ferreira

; Fernandes, Marcio Pimentel

; Ardito, Roberto Vito

; Bogdan, Renata Andrea Barberio

; Campagnucci, Valquíria Pelisser

; Nakasako, Diana

; Kalil, Renato Abdala Karam

; Rodrigues, Clarissa Garcia

; Rodrigues Junior, Anilton Bezerra

; Cascudo, Marcelo Matos

; Atik, Fernando Antibas

; Lima, Elson Borges

; Nina, Vinicius José da Silva

; Heluy, Renato Albuquerque

; Azeredo, Lisandro Gonçalves

; Henrique Junior, Odilon Silva

; Mendonça, José Teles de

; Silva, Katharina Kelly de Oliveira Gama

; Pandolfo, Marcelo

; Lima Júnior, José Dantas de

; Faria, Renato Max

; Santos, Jonas Gonçalves dos

; Paez, Rodrigo Pereira

; Coelho, Guilherme Henrique Biachi

; Pereira, Sergio Nunes

; Senger, Roberta

; Buffolo, Enio

; Caputi, Guido Marco

; Santo, José Amalth do Espírito

; Oliveira, Juliana Aparecida Borges de

; Berwanger, Otavio

; Cavalcanti, Alexandre Biasi

; Jatene, Fabio B.

Brazilian Journal of Cardiovascular Surgery

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apr 2017, Volume 32 N. 2 Pages 71 - 76

Abstract: En | Text: En | PDF: En

Abstract Objective: To report the early results of the BYPASS project - the Brazilian registrY of adult Patient undergoing cArdiovaScular Surgery - a national, observational, prospective, and longitudinal follow-up registry, aiming to chart a profile of patients undergoing cardiovascular surgery in Brazil, assessing the data harvested from the initial 1,722 patients. Methods: Data collection involved institutions throughout the whole country, comprising 17 centers in 4 regions: Southeast (8), Northeast (5), South (3), and Center-West (1). The study population consists of patients over 18 years of age, and the types of operations recorded were: coronary artery bypass graft (CABG), mitral valve, aortic valve (either conventional or transcatheter), surgical correction of atrial fibrillation, cardiac transplantation, mechanical circulatory support and congenital heart diseases in adults. Results: 83.1% of patients came from the public health system (SUS), 9.6% from the supplemental (private insurance) healthcare systems; and 7.3% from private (out-of -pocket) clinic. Male patients comprised 66%, 30% were diabetics, 46% had dyslipidemia, 28% previously sustained a myocardial infarction, and 9.4% underwent prior cardiovascular surgery. Patients underwent coronary artery bypass surgery were 54.1% and 31.5% to valve surgery, either isolated or combined. The overall postoperative mortality up to the 7th postoperative day was 4%; for CABG was 2.6%, and for valve operations, 4.4%. Conclusion: This first report outlines the consecution of the Brazilian surgical cardiac database, intended to serve primarily as a tool for providing information for clinical improvement and patient safety and constitute a basis for production of research protocols.

https://doi.org/10.21470/1678-9741-2017-0053 1883 downloads

11.

Intemperismo Artificial em Lâminas de Tectona grandis Tratadas com Produtos de Acabamento
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Queiroz, Francis Lívio Corrêa

; Gonçalez, Joaquim Carlos

; del Menezzi, Cláudio Henrique

; Ribeiro, Edilene Silva

; Lima, Clarissa Melo

Floresta e Ambiente

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dec 2016, Volume 23 N. 4 Pages 573 - 581

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este estudo teve por objetivo avaliar a ação do tempo de exposição ao intemperismo artificial na cor de lâminas de madeiras de teca tratadas com produtos de acabamento. Amostras que receberam 2 tipos de produto, a seladora e o stain, mais as testemunhas, sem acabamento. O experimento foi instalado no delineamento inteiramente casualizado, com 3 tratamentos e 4 repetições. As lâminas ficaram expostas ao simulador QUV-Acelerated Weathering Teste, por 7 períodos, de: 6, 12, 24, 48, 96, 192 e 384 horas. Após cada período de intemperismo foram feitas medições das cores, com espectrofotômetro COLOR EYe XTH. As variáveis cromáticas avaliadas foram: L*, a*, b*, C e h*. Ao final do estudo pôde-se concluir que as lâminas de madeira de teca sofreram alterações em sua cor com o passar do tempo de exposição e que o stain apresentou maior eficiência na conservação da cor da madeira.

ABSTRACT This study aims to evaluate the effects of weather exposure to artificial weathering in the color of teak wood veneer treated with finishing products. The samples received 2 types of products, the sealer and the stain, plus witnesses, unfinished. The experiment was conducted in a completely randomized design with 3 treatments and 4 replications. Slides were exposed to QUV-Accelerated Weathering Test simulator for 7 periods as follow: 6, 12, 24, 48, 96, 192 and 384 hours. Color measurements were made after each period of weathering using the spectrophotometer Color Eye XTH. The chromatic variables evaluated were: L *, a *, b *, C * and h*. The study concluded that the teak wood veneer had color alterations with the exposure time and the stain was more efficient in preserving the wood color.

https://doi.org/10.1590/2179-8087.126315 870 downloads

12.

Antiviral activity of a Bacillus sp: P34 peptide against pathogenic viruses of domestic animals
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Silva, Débora Scopel e

; Castro, Clarissa Caetano de

; Silva, Fábio da Silva e

; Sant'anna, Voltaire

; Vargas, Gilberto D'Avila

; Lima, Marcelo de

; Fischer, Geferson

; Brandelli, Adriano

; Motta, Amanda de Souza da

; Hübner, Silvia de Oliveira

Brazilian Journal of Microbiology

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sep 2014, Volume 45 N. 3 Pages 1089 - 1094

Abstract: En | Text: En | PDF: En

P34 is an antimicrobial peptide produced by a Bacillus sp. strain isolated from the intestinal contents of a fish in the Brazilian Amazon basin with reported antibacterial activity. The aim of this work was to evaluate the peptide P34 for its in vitro antiviral properties against canine adenovirus type 2 (CAV-2), canine coronavirus (CCoV), canine distemper virus (CDV), canine parvovirus type 2 (CPV-2), equine arteritis virus (EAV), equine influenza virus (EIV), feline calicivirus (FCV) and feline herpesvirus type 1 (FHV-1). The results showed that the peptide P34 exhibited antiviral activity against EAV and FHV-1. The peptide P34 inhibited the replication of EAV by 99.9% and FHV-1 by 94.4%. Virucidal activity was detected only against EAV. When P34 and EAV were incubated for 6 h at 37 °C the viral titer reduced from 10(4.5) TCID50 to 10(2.75) TCID50, showing a percent of inhibition of 98.6%. In conclusion, our results demonstrated that P34 inhibited EAV and FHV-1 replication in infected cell cultures and it showed virucidal activity against EAV. Since there is documented resistance to the current drugs used against herpesviruses and there is no treatment for equine viral arteritis, it is advisable to search for new antiviral compounds to overcome these infections.

2599 downloads

13.

Experimental model of intracranial hypertension with continuous multiparametric monitoring in swine
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Andrade, Almir Ferreira de

; Soares, Matheus Schmidt

; Patriota, Gustavo Cartaxo

; Belon, Alessandro Rodrigo

; Paiva, Wellingson Silva

; Bor-Seng-Shu, Edson

; Oliveira, Marcelo de Lima

; Nascimento, Clarissa Nobrega

; Noleto, Gustavo Sousa

; Alves Junior, Aderaldo Costa

; Figueiredo, Eberval Gadelha

; Otoch, Jose Pinhata

; Teixeira, Manoel Jacobsen

Arquivos de Neuro-Psiquiatria

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oct 2013, Volume 71 N. 10 Pages 802 - 806

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo A hipertensão intracraniana (HIC) ocorre em até 50% de todos os pacientes com traumatismo cranioencefálico (TCE). Por isso, é importante estabelecer um modelo animal adequado para estudar a fisiopatologia da HIC refratária, com a perspectiva de desenvolver tratamentos eficazes. Métodos Os animais foram submetidos a um protocolo padrão de anestesia. A hipertensão intracraniana foi estabelecida através de insuflação de um balão. As variáveis HIC foram medidas com a pressão intracraniana (PIC) do parênquima, oximetria, epidural e doppler transcraniano. Resultados A PIC epidural apresentou elevação mais lenta, comparada com a PIC parenquimal. Houve correlação entre a PIC e a oximetria cerebral. O registro da PIC, oximetria e índice de pulsatilidade foi realizado em todos os animais sem dificuldade. Conclusão O modelo descrito parece ser útil para a compreensão de algumas características fisiopatológicas na HIC aguda.

Objective Intracranial hypertension (IH) develops in approximately 50% of all patients with severe traumatic brain injury (TBI). Therefore, it is very important to identify a suitable animal model to study and understand the pathophysiology of refractory IH to develop effective treatments. Methods We describe a new experimental porcine model designed to simulate expansive brain hematoma causing IH. Under anesthesia, IH was simulated with a balloon insufflation. The IH variables were measured with intracranial pressure (ICP) parenchymal monitoring, epidural, cerebral oximetry, and transcranial Doppler (TCD). Results None of the animals died during the experiment. The ICP epidural showed a slower rise compared with parenchymal ICP. We found a correlation between ICP and cerebral oximetry. Conclusion The model described here seems useful to understand some of the pathophysiological characteristics of acute IH.

https://doi.org/10.1590/0004-282X20130126 3380 downloads

14.

A desigualdade espacial do Baixo Peso ao Nascer no Brasil
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Lima, Marina Clarissa Barros de Melo

; Oliveira, Genyklea Silva de

; Lyra, Clélia de Oliveira

; Roncalli, Angelo Giuseppe

; Ferreira, Maria Angela Fernandes

Ciência & Saúde Coletiva

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aug 2013, Volume 18 N. 8 Pages 2443 - 2452

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O baixo peso ao nascer (BPN) é fator de risco para a morbidade, mortalidade neonatal e infantil. No Brasil os maiores percentuais de baixo peso ao nascer ocorrem em regiões de melhor situação socioeconômica. O objetivo deste artigo é conhecer a distribuição espacial de taxas de baixo peso ao nascer e a correlação com indicadores sociais e de serviço. Desenho: ecológico, tendo os estados brasileiros como unidades de análise. Utilizou-se técnica de análise espacial, dados de 2009 do SINASC, IPEA e IBGE. Taxas maiores de baixo peso ao nascer estão nos estados da região sul/sudeste, Moran Global: 0,267, p = 0,02. Aglomerados do tipo alto-alto na região Sudeste e baixo-baixo em estados da região da Amazônia Legal. A desigualdade espacial do baixo peso ao nascer reflete as condições socioeconômicas dos estados. Regiões mais desenvolvidas detêm maiores taxas de baixo peso ao nascer, portanto, a presença do serviço e sua utilização fazem diminuir a mortalidade infantil e aumentar o BPN.

Low birth weight (LBW) is a risk factor for neonatal and infant morbidity and mortality. In Brazil the highest percentages of low birth weight occur in regions of higher socio-economic status. The scope of this article is to ascertain the spatial distribution of low birth weight rates and the correlation with social and service indicators. The scale is ecological taking all the Brazilian states as units of analysis. The spatial analysis technique is the methodology used together with data from SINASC, IPEA and IBGE for 2009. Higher rates of low birth weight are found in the south/southeastern states (Global Moran: 0.267, p = 0.02). Clusters of the high-high type in the Southeast and of the low-low variety in states in the Amazon region are detected. The spatial inequality of low birth weight reflects the socio-economic conditions of the states. More developed regions have higher rates of low birth weight, therefore, the presence of the service and its use decrease infant mortality and increase LBW.

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15.

A desigualdade espacial do Baixo Peso ao Nascer no Brasil
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Lima, Marina Clarissa Barros de Melo

; Oliveira, Genyklea Silva de

; Lyra, Clélia de Oliveira

; Roncalli, Angelo Giuseppe

; Ferreira, Maria Angela Fernandes

Ciência & Saúde Coletiva

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aug 2013, Volume 18 N. 8 Pages 2443 - 2452

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/S1413-81232013000800029 3084 downloads

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