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[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Publication date: 2024-04-08

Abstract: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

[SciELO Preprints] - Kalman Filters in crop models: old experiences in new contexts
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Oliveira, Monique Pires Gravina de Zorzeto-Cesar, Thais Queiroz Attux, Romis Ribeiro de Faissol Rodrigues, Luiz Henrique Antunes

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Publication date: 2024-02-06

Abstract: En

Data assimilation has been widely used for improvement of crop models’ estimates, for example to incorporate the effects of external events or compensate calibration errors in large areas. The term describes multiple approaches for those who want to take advantage of satellite imagery to reduce uncertainty or improve accuracy of model estimates. Kalman Filters are among the most used methods for achieving these goals. But their use in new contexts, i.e., from open field to protected environments, requires untangling aspects of the pipeline that are often performed in many different ways without guidelines, such as which variables to assimilate or how to ascribe uncertainty to observations or model estimates. This study is then divided in two parts. In the first, we review details on how uncertainty is ascribed on crop model estimates and in observations for applications of the Kalman Filter and three variations of the method, i.e., the Extended, Unscented and Ensemble, as well as which state variables are often updated and the frequency with which assimilation may occur, as well as how these aspects are connected to each other. In the second part, we apply different approaches from the reviewed literature in a greenhouse tomato crop model. We use artificial data with controlled noise levels as well as artificial data generated by simulation using other tomato crop model. We assess the impacts of using different methods and different approaches for ascribing uncertainty in model estimates and in observations, by assimilating artificial observations of fruit and of mature fruit biomass. We note that covariances should not be fixed values, that there are trade-offs between ascribing model uncertainty to the state itself and to other elements of the process, that observation covariance may have been considered disproportionality higher when using some ensemble generation approaches in the EnKF, and that bias in model estimates may lead to worse outcomes even when observations are high-quality ones. While we discussed aspects that should be considered in a new environment, many of them are also important for field crops, and we concluded assimilation should follow an assessment of which variables could be useful for assimilation.

https://doi.org/10.1590/SciELOPreprints.8033

The absence of eosinophils is associated with early metastatic lesions in Leishmania amazonensis-infected mice
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Almeida, Gregório Guilherme

; Luehring, Tassiane Assíria Martins

; Paixão, Pierre Henrique de Menezes

; Soares, Rodrigo Pedro

; de Barros, André Luís Branco

; do Monte-Neto, Rubens Lima

; Tafuri, Wagner Luiz

; Negrão-Corrêa, Deborah Aparecida

; Gonçalves, Ricardo

Memórias do Instituto Oswaldo Cruz

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2024, Volume 119 elocation e220242

Abstract: En | Text: En | PDF: En

BACKGROUND Eosinophils are granulocytes that rapidly increase frequency in the bloodstream during helminthic infections and allergic responses. They are found in tissue infected by Leishmania during early disease, but their role during infection is not entirely understood. OBJECTIVES We aim to compare the disease due to Leishmania amazonensis in BALB/c and Δdbl-GATA1 mice, which lack eosinophils. METHODS BALB/c and Δdbl-GATA1 mice infected with L. amazonensis were observed for several weeks. The parasite load and dissemination pattern were assessed. FINDINGS The Δdbl-GATA1 mice developed an anticipated dissemination of L. amazonensis and a worsening disease. No differences were found in the lesion development or the parasite load in the footpad among Δdbl-GATA1 mice and BALB/c eight weeks after infection. However, nine weeks after infection, massive growth of metastatic lesions appeared in several parts of the skin in Δdbl-GATA1 mice, weeks earlier than BALB/c. We observed increased parasites in the bloodstream, probably an essential dissemination route. Thirteen weeks after infection, metastatic lesions were found in all Δdbl-GATA1 mice. MAIN CONCLUSION These results suggest a protective role of eosinophils in delaying the disease caused by L. amazonensis, although several limitations of this mice strain must be considered.

https://doi.org/10.1590/0074-02760220242

Knowledge and attitudes of rural healthcare providers regarding domestic violence against women: a systematic review
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Nascimento, Cláudio Tarso de Jesus Santos

; Vidigal, Maria Tereza Campos

; Oliveira, Vinícius Henrique Ferreira Pereira de

; Franco, Raquel Porto Alegre Valente

; Vieira, Walbert Andrade

; de-Jesus-Soares, Adriana

; Lima, Rafael Rodrigues

; Franco, Ademir

; Paranhos, Luiz Renato

Sao Paulo Medical Journal

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2024, Volume 142 N. 3 elocation e2022682

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Specific types of violence such as intimate partner sexual violence and intimate partner homicide occur more frequently in rural areas. OBJECTIVE: This study aimed to systematically review the literature on the knowledge and attitudes of rural healthcare providers regarding cases of domestic violence against women. DESIGN AND SETTING: Systematic review developed at Universidade Federal de Uberlândia. METHODS: We conducted an electronic search of six databases, which only included observational studies, regardless of the year, language, or country of publication, except for studies that used secondary data and were exclusively qualitative. Two reviewers performed the selection, data extraction, and risk of bias assessment using a specific Joanna Briggs Institute tool. RESULTS: Six studies met the inclusion criteria. All the studies had a low risk of bias. Approximately 38% of these professionals identified injuries caused by violence in patients. When asked about knowing the correct attitude to take in cases of confirmed violence, between 12% and 64% of rural healthcare providers answered positively; most of them would refer to specialized institutions and promote victim empowerment and counseling. The number of professionals with an educational background in the field ranged from 16% to 98%. CONCLUSIONS: The evident disparity across studies shows that some professionals have suboptimal knowledge and require training to adopt the correct attitude when identifying female victims of domestic violence in clinical practice. SYSTEMATIC REVIEW REGISTRATION: This systematic review was registered in the Open Science Framework Database under the registration http://doi.org/10.17605/OSF.IO/B7Q6S.

https://doi.org/10.1590/1516-3180.2022.0682.r1.180723

Performance Evaluation of Geometrically Different Pediatric Arterial Cannulae in a Pediatric Cardiopulmonary Bypass Model
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Carvalho, Gabriela B. de O.

; Caneo, Luiz Fernando

; Matte, Gregory

; Cruz, Caio Henrique de A.

; Silva, Everton Neri da

; Carletto, Luciana P.

; Castro, Ana Vitória C. X. de

; Silva, Betina G. Madueño

; Policarpo, Valéria C.

; Cestari, Idágene A.

; Jatene, Fabio B

; Jatene, Marcelo Biscegli

Brazilian Journal of Cardiovascular Surgery

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2024, Volume 39 N. 1 elocation e20230110

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To define a reference chart comparing pressure drop vs. flow generated by a set of arterial cannulae currently utilized in cardiopulmonary bypass conditions in pediatric surgery. Methods: Cannulae from two manufacturers were selected considering their design and outer and inner diameters. Cannula performance was evaluated in terms of pressure drop vs. flow during simulated cardiopulmonary bypass conditions. The experimental circuits consisted of a Jostra HL-20 roller pump, a Quadrox-i pediatric oxygenator (Maquet Cardiopulmonary AG, Rastatt, Germany), and a custom pediatric tubing set. The circuit was primed with lactated Ringer’s solution only (first condition) and with human packed red blood cells added (second condition) to achieve a hematocrit of 30%. Cannula sizes 8 to 16 Fr were inserted into the cardiopulmonary bypass circuit with a “Y” connector. The flow was adjusted in 100 ml/min increments within typical flow ranges for each cannula. Pre-cannula and post-cannula pressures were measured to calculate the pressure drop. Results: Utilizing a pressure drop limit of 100 mmHg, our results suggest a recommended flow limit of 500, 900, 1400, 2600, and 3100 mL/min for Braile arterial cannulae sizes 8, 10, 12, 14, and 16 Fr, respectively. For Medtronic DLP arterial cannulae sizes 8, 10, 12, 14, and 16 Fr, the recommended flow limit is 600, 1100, 1700, 2700, and 3300 mL/min, respectively. Conclusion: This study reinforces discrepancies in pressure drop between cannulae of the same diameter supplied by different manufacturers and the importance of independent translational research to evaluate components’ performance.

https://doi.org/10.21470/1678-9741-2023-0110

Use of surgical videos available on social media among retina surgeons: results of a vitreoretinal specialist survey
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Lucatto, Luiz Filipe Adami

; Barbosa, Gabriel Castilho Sandoval

; Prazeres, Juliana Moura Bastos

; Cardoso, Emmerson Badaró

; Guerra, Ricardo Luz Leitão

; Lima, Luiz Henrique Soares Gonçalves de

; Rodrigues, Eduardo Büchele

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 4 elocation e2022-0166

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: This study aimed to assess and interpret how vitreoretinal surgeons use surgical videos available on social media as complementary learning tools to improve, review, or update their abilities, considering their different levels of expertise. Methods: In this cross-sectional survey, an online survey was sent to vitreoretinal specialists and fellows. Results: This survey included 258 participants, of whom 53.88% had been in practice for >10 years (senior surgeons), 29.07% between 4 and 10 years (young surgeons), and 17.05% for <3 years (surgeons in training). Retinal surgical videos available on social media were used by 98.84% of the participants (95% confidence interval, 97.52%-100%). YouTube (91%) was the most common source of videos, and surgeons in training watched more videos on YouTube than senior surgeons. Regarding the preferred method when preparing for a procedure, 49.80% of the participants watched surgical videos available on social media, 26.27% preferred to “consult colleagues”, and 18.82% preferred to seek information in scientific articles. Participants valued the most the “image quality” (88%) and presence of “surgical tips and tricks” (85%). Conclusion: Surgical videos can provide benefits in acquiring strategic skills, such as decision-making, surgical planning, and situational awareness. Retina surgeons used them as teaching aids regardless of their level of expertise, despite being relatively more valuable to surgeons in training or young surgeons.

RESUMO Objetivo: Avaliar e interpretar como os cirurgiões vitreorretinianos utilizam os vídeos cirúrgicos disponíveis nas mídias sociais como ferramentas complementares de aprendizagem para melhorar, revisar ou atualizar suas habilidades, considerando seus diferentes níveis de especialização. Métodos: Nesta pesquisa transversal, um survey online foi enviado à especialistas e aprendizes na área vítreo-retiniana. Resultados: Esta pesquisa incluiu 258 participantes, dos quais 53,88% atuavam há mais de 10 anos (cirurgiões seniores), 29,07% entre 4 e 10 anos (cirurgiões jovens) e 17,05% há menos de 3 anos (cirurgiões em treinamento). Vídeos cirúrgicos de retina nas mídias sociais foram usados por 98,84% dos participantes (intervalo de confiança de 95%, 97,52%-100%). A fonte mais comum de acesso aos vídeos foi o YouTube (91%), e o grupo de cirurgiões com menos de 3 anos de experiência assistiu mais vídeos no YouTube em comparação aos cirurgiões seniores. Assistir a vídeos cirúrgicos nas redes sociais foi o método preferido na preparação para um procedimento para 49,80% dos participantes versus 26,27% que preferiram “consultar colegas” e 18,82% que preferiram buscar informações em artigos científicos. A “qualidade de imagem” (88%) e a presença de “dicas e truques cirúrgicos” (85%) foram as características dos vídeos mais valorizadas pelos participantes. Conclusão: O uso de vídeos cirúrgicos pode trazer benefícios na aquisição de habilidades estratégicas, como tomada de decisão, planejamento cirúrgico e consciência situacional. Sua aplicação como auxiliar de ensino foi utilizada por cirurgiões de retina independentemente de seu nível de especialização, apesar de ser relativamente mais valioso para cirurgiões em formação ou com menos de 10 anos de experiência.

https://doi.org/10.5935/0004-2749.2022-0166

Esophageal and gastric pythiosis in a dog
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Silva, Emanoelly Machado Sousa da

; Martins, Kamila Peruchi Fernandes

; Pereira, Asheley Henrique Barbosa

; Gris, Anderson Hentz

; Maruyama, Fernanda Harumi

; Nakazato, Luciano

; Colodel, Edson Moleta

; Oliveira, Luiz Gustavo Schneider de

; Boabaid, Fabiana Marques

Ciência Rural

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2024, Volume 54 N. 6 elocation e20230272

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: Pythiosis is the disease caused by aquatic oomycetes of the genus Pythium. In dogs the typical course of the disease involves the gastrointestinal tract, characterized by transmural thickening of the stomach or intestines. However, infection by Pythium spp. has only rarely been recognized as a cause of esophagitis in dogs. Thus, the present reports a case of esophageal and gastric pythiosis in an eight-month-old female pit bull dog. The dog was attended at the hospital after two months presenting regurgitation and dyspnea. It was reported that the dog lived in an urban area and had no previous sanitary issues. At clinical examination it was noted that the dog presented crackling sounds at pulmonary auscultation. A support therapy accompanied by antibiotics has been employed; however, 22 days after hospitalization the clinical condition worsened, and the dog died. At necropsy, the wall of the distal segment of the esophagus and the cardia and part of the fundus of the stomach were expanded by a focal extensive irregular intramural annular mass. Additionally, there was a transmural esophageal fistula. At histology, the walls of the esophagus and stomach were extensively expanded by multifocal extensive areas of necrosis, associated with a pyogranulomatous infiltrate and abundant granulation tissue containing multiple negative images of hyphae that were highlighted by silver impregnation (Grocott). Furthermore, immunohistochemistry and PCR for P. insidiosum were both positive in samples of paraffin-embedded esophageal tissue.

RESUMO: A Pitiose é uma doença causada por oomicetos aquáticos do gênero Pythium. Em cães o curso típico da doença envolve o trato gastrointestinal, caracterizado por espessamento transmural do estômago ou intestinos. No entanto, a infecção por Pythium spp. raramente foi reconhecida como causa de esofagite em caninos. Assim, o presente trabalho tem como objetivo relatar um caso de pitiose esofágica e gástrica em um canino Pit Bull fêmea de oito meses de idade. O cão foi recebido no hospital com histórico de regurgitação e dispneia durante dois meses. Foi relatado que o animal era de um domicílio de área urbana e não possuía histórico pregresso de enfermidades. No exame clínico contatou-se ainda crepitações à ausculta pulmonar. Foi instituído tratamento de suporte e antibioticoterapia, porém após 22 dias de internação, o cão evoluiu para o óbito. Na necropsia, as paredes do segmento distal do esôfago e o cárdia e parte do fundo do estômago estavam expandidos por uma massa anular intramural focalmente extensiva e irregular. Além disso, havia uma fístula esofágica transmural. À histologia, as paredes do esôfago e do estômago apresentavam-se difusamente expandidas por áreas multifocais extensas de necrose, associadas a infiltrado piogranulomatoso, abundante proliferação de fibroblastos imaturos, neovascularização e contendo múltiplas imagens negativas de hifas realçadas pela impregnação por prata (Grocott). Além disso, tanto a imuno-histoquímica como PCR para P. insidiosum foram positivas em amostras de esôfago embebidas em parafina.

https://doi.org/10.1590/0103-8478cr20230272

Seismic fragility assessment of a RC frame considering concentrated and distributed plasticity modelling
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Rodrigues, Isabela Durci

; Cavalcante, Gustavo Henrique Ferreira

; Pereira, Eduardo Marques Vieira

; Vieira Júnior, Luiz Carlos Marcos

; Liel, Abbie

; Siqueira, Gustavo Henrique

Revista IBRACON de Estruturas e Materiais

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2024, Volume 17 N. 1 elocation e17105

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Pesquisadores devem decidir sobre como modelar a resposta não linear do material em uma simulação com Elementos Finitos para avaliar a vulnerabilidade sísmica. Esse trabalho pretende auxiliar nessa tomada de decisão ao comparar os modelos de Fibra e de Plasticidade Concentrada em Elementos Finitos em análises não lineares estáticas e dinâmicas de um pórtico em concreto armado. A metodologia é baseada na engenharia de desempenho sísmico (PBEE) para determinar o dano nas estruturas. Os resultados indicam que os dois modelos apresentam uma boa correspondência em uma análise estática, e ao considerar os Estados Limite de Dano Extensivo e Completo na análise dinâmica. A escolha entre os dois depende dos objetivos principais do pesquisador e dos recursos disponíveis, já que eles apresentam uma significativa diferença no tempo de processamento. sísmica armado PBEE (PBEE estruturas estática dinâmica disponíveis processamento

Abstract Researchers must decide on how they will model the non-linear material response in a Finite Element simulation to assess seismic vulnerability. This paper aims at giving an insight into these modelling decisions by comparing Fiber and Lumped Plasticity Finite Element Models in static and dynamic non-linear analysis in a RC frame. The methodology is based on the performance-based earthquake engineering to determine the expected damage on structures. The results indicate that both models are in good agreement with the static analysis, and when considering Extensive and Complete Damage Limit States on the dynamic analysis. The choice between them depends on the main goals of the research and resources available, since they have a significant difference in processing time. nonlinear non linear vulnerability frame performancebased performance structures available time

https://doi.org/10.1590/s1983-41952024000100005

Notified cases of mpox in the city of Rio de Janeiro, Brazil: a descriptive study, 2022
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Ribeiro, Caio Luiz Pereira

; D’Oliveira, Camila Arantes Ferreira Brecht

; Campos, Élida de Albuquerque

; Carvalho, Luciana Freire de

; Pinto, Luciana de Almeida

; Duffrayer, Karoline Moreira

; Magalhães, Poliana Hilário

; Proença, Raquel

; Cerbino Neto, José

; Aguilar, Gislani Mateus Oliveira

; Garcia, Márcio Henrique de Oliveira

Epidemiologia e Serviços de Saúde

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2024, Volume 33 elocation e2023899

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

RESUMEN Objetivo Describir el perfil de los casos de mpox en la ciudad de Río de Janeiro entre junio y noviembre de 2022. Métodos Estudio descriptivo de datos secundarios de los formularios de notificación de mpox. Se analizaron datos socioeconómicos, clínicos y espaciales. Resultados De los 928 casos, 93,7% eran hombres, 65,6% homosexuales, 41% blanca, y 41,8% de 30 a 39 años. Estaban inmunocomprometidos debido a una enfermedad 34,5%, y 41,9% reportaron serología positiva para virus de inmunodeficiencia humana. Signos y síntomas más prevalentes fueron: lesiones cutáneas (96,6%), con manifestaciones múltiples (67,8%) y en la región genital (46,1%), además de fiebre (58,3%), adenomegalia (43,3%) y cefalea (38,7%). Mayoría de las notificaciones ocurrieron en la red pública (81,3%) y atención hospitalaria (51,3%). Conclusión El estudio reveló alta incidencia de mpox, especialmente entre hombres jóvenes, cisgénero y homosexuales. Mayoría de los casos tuvieron una presentación leve, progresando hasta la curación sin hospitalización.

RESUMO Objetivo Descrever o perfil dos casos de mpox na cidade do Rio de Janeiro, entre junho e novembro de 2022. Métodos Estudo descritivo de dados secundários das fichas de notificação de mpox. Foram analisados dados socioeconômicos, clínicos e espaciais. Resultados Dos 928 casos, 93,7% foram do sexo masculino, 85,0% homem cisgênero, 65,6% homossexual, 41,8% entre 30 e 39 anos e 41,0% brancos. Apresentavam imunodepressão por doença 34,5%, e 41,9% informaram sorologia positiva prévia para vírus da imunodeficiência humana. Os sinais e sintomas mais prevalentes foram: lesões cutâneas (96,6%), especialmente com manifestações múltiplas (67,8%) e em região genital (46,1%), além de febre (58,3%), adenomegalia (43,3%) e cefaleia (38,7%). A maioria das notificações ocorreu na rede pública (81,3%) e na atenção hospitalar (51,3%). Conclusão O estudo revelou maior incidência de mpox entre homens cisgênero, autodeclarados de cor branca e homossexual. A maioria dos casos teve apresentação leve evoluindo para cura sem hospitalização.

ABSTRACT Objective To describe the profile of cases of mpox in the city of Rio de Janeiro between June and November 2022. Methods This was a descriptive study of secondary data obtained from mpox notification forms. Socioeconomic, clinical and spatial data were analyzed. Results Of the 928 cases, 93.7% were male, 85.0% cisgender male, 65.6% homosexual, 41.8% between 30 and 39 years old, and 41.0% were of White race/skin color. A total of 34.5% had immunosuppression due to illness, and 41.9% reported their HIV status as being positive. The most prevalent signs and symptoms were: skin lesions (96.6%), especially with multiple manifestations (67.8%) in the genital region (46.1%), in addition to fever (58.3%), adenomegaly (43.3%) and headache (38.7%). Most notifications occurred in public services (81.3%) and in hospital care (51.3%). Conclusion The study revealed high incidence of mpox, especially among young, cisgender and homosexual men. Most cases were mild, with genital lesions, progressing to cure without hospitalization. Person-to-person transmission was predominant.

https://doi.org/10.1590/s2237-96222024v33e2023899.en

10.

A prática pedagógica reflexiva em questão: Estudo de caso de uma escola brasileira
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Oliveira, Terezinha Marisa Ribeiro de

; Amaral, Luiz Henrique

; Amaral, Carmem Lúcia Costa

Revista Portuguesa de Educação

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dec 2023, Volume 36 N. 2 elocation e23027

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO No Brasil, a teoria do professor reflexivo vem sendo alvo de discussão em cursos de formação continuada e nos documentos oficiais orientadores de formação inicial. Entretanto, será que os professores desenvolvem uma prática reflexiva, ou essa prática fica só nas orientações documentais? Com o objetivo de responder a esse questionamento, realizamos uma pesquisa com quinze professores de uma escola pública localizada no estado de São Paulo, Brasil. Para essa pesquisa, baseamo-nos em três questões propostas por McKay (2008). Essas questões versaram sobre o planejamento das atividades pedagógicas, em que se baseavam para avaliar as suas aulas e em que momento refletiam sobre sua prática. Os resultados evidenciaram que a maioria segue o currículo do estado de São Paulo, e as reações dos alunos foram o parâmetro mais utilizado para a avaliação das aulas ministradas, nas quais os professores desenvolvem principalmente a reflexão na ação. Com essa pesquisa percebemos que para esse grupo de professores, torna-se importante um aprofundamento da reflexão sobre as suas práticas.

ABSTRACT In Brazil, the theory of reflective teacher has been the subject of discussion in continuing education courses and in the official documents that guide initial education. However, do teachers actually develop a reflective practice, or does such practice remains only in official guidelines? In order to answer this question, we conducted a research with fifteen teachers from a public school located in the state of São Paulo, Brasil. For this research, we based ourselves on three questions proposed by McKay (2008). These questions were about the planning of pedagogical activities, what they used to evaluate their classes and when they reflected on their practice. The results showed that most of the teachers follow São Paulo state curriculum; and the students’ reactions were the most used parameter for the evaluation of their classes, in which teachers mainly develop the reflection on action. With this research we realized that for this group of teachers, it is important to deepen the reflection on their practices.

RESUMEN En Brasil, la teoría del profesor reflexivo ha sido discutida en cursos de formación continua y en los documentos oficiales que orientan la formación inicial. Sin embargo, ¿desarrollan los docentes una práctica reflexiva, o esta práctica está solo en las pautas documentales? Para responder a esta pregunta, realizamos una encuesta con quince profesores de una escuela pública ubicada en el estado de São Paulo, Brasil. Para esta investigación, nos basamos en tres preguntas propuestas por McKay (2008). Estas preguntas fueron sobre la planificación de las actividades pedagógicas, qué utilizaban para evaluar sus clases y en qué momento reflexionaban sobre su práctica. Los resultados mostraron que la mayoría sigue el currículo del estado de São Paulo, y las reacciones de los estudiantes fueron el parámetro más utilizado para la evaluación de las clases impartidas, en las que los docentes desarrollan principalmente la reflexión en acción. Con esta investigación, nos damos cuenta de que para este grupo de profesores es importante profundizar la reflexión sobre sus prácticas.

https://doi.org/10.21814/rpe.24860

11.

[SciELO Preprints] - Dataset of tomato plants growth observations obtained from multiple sources in a production-like setting
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Oliveira, Monique Amaro, Rafaella Pescarini, Henrique Rodrigues, Luiz Henrique

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Publication date: 2023-12-11

Abstract: En

This dataset contains observations of tomato growth in a production-like setting, at research greenhouses. Two plants in each of three growth cycles were continuously monitored and pictures were taken every other day from above and from a side view while a weighting system was used to record changes in weight of plant and water in the substrate. Other plants in the environment were subjected to destructive analysis in general every two weeks to quantify aspects of growth that required destructive measurements, such as dry weight and plant leaf area, and these records are also included in the dataset, including the scans of digitized leaves. Plant samples destined to destructive measurements also had their pictures taken before removal. In total, 618 photos of monitored and removed plants were annotated, and masks of leaf, fruit and mature fruit are also provided. The dataset also includes measurements of photosynthetically active radiation and air temperature recorded inside the greenhouses by two sets of different sensors during the growth cycles. The dataset allows for applications regarding growth monitoring and computer vision tasks.

https://doi.org/10.1590/SciELOPreprints.7667

12.

[SciELO Preprints] - Leveraging data from plant monitoring into crop models
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Oliveira, Monique Zorzeto-Cesar, Thais Attux, Romis Rodrigues, Luiz Henrique

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Publication date: 2023-12-08

Abstract: En

Researchers using crop models have been devising new roles for data and crop modeling based on the former’s increased availability and the new techniques developed for the latter. From the various available techniques, modeling may be tackled by data-driven methods or through a process-based approach. Process-based or mechanistic models may nonetheless take advantage of real-time observations through data assimilation. And while this approach has been widely used for field crops, this is not the case for crops grown in protected environments. We present a case study of data assimilation in a protected environment, capturing tomato growth data from different sources. We updated growth estimates of the Reduced State TOMGRO model, by assimilating observational data obtained through the continuous monitoring of plant mass and images captured by low-cost cameras, using the Unscented Kalman Filter and the Ensemble Kalman Filter. Since these techniques had not been used yet in the protected cultivation of tomatoes, it was necessary to develop the observation models as well, establishing the relationship between the observed variables and the ones estimated by the process-based model. The employed measurements, i.e., area of organs observed in pictures and plant-water mass, seemed suitable for tracking plant growth and for obtaining good approximations of the state variables estimated by the model. However, the quality of observations and of observation models was crucial for good performance of the assimilation techniques. As with other crops, it was not the case that assimilating one observation was useful for improving the value of others, including yield. We also observed that the assimilation performed better than calibrated models when there was a need to adjust the estimates to growth disturbances and that when filters lead to better yield estimates, continuous observations may not be required. There are then several steps and decisions that should be considered when bringing the idea from its application in field crops to protected environments and more studies are required to better determine the best approach.

https://doi.org/10.1590/SciELOPreprints.7663

13.

Processo de organização do trabalho dos Núcleos Ampliados de Saúde da Família e Atenção Básica durante a pandemia da Covid-19 no Brasil
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Santos, Hebert Luan Pereira Campos dos

; Prado, Nília Maria de Brito Lima

; Santos, Luiz Henrique Pitanga Evangelista dos

; Maciel, Fernanda Beatriz Melo

; Pereira, Luzimary Vieira

; Teixeira, Carmen Fontes

Saúde em Debate

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dec 2023, Volume 47 N. 139 Pages 978 - 992

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The aim of this article is to identify organizational strategies and operational challenges to implement the multidisciplinary work process of the Expanded Family Health and Primary Healthcare Center (NASF-AB) teams in the context of the COVID-19 pandemic in Brazil. This is an integrative review study in the LILACS and Science Direct databases, PubMed, Virtual Health Library (VHL), Scientific Electronic Library Online (SciELO), Google Scholar and document review of technical publications (protocols, technical notes, letters, ordinances) on the official website of the Brazilian Ministry of Health. Thirteen studies were included and no technical documents published by the Ministry of Health were located which dealt directly with the reorganization of the NASF-AB work process during the pandemic. It was evidenced that the elements that make up the teamwork process have been modified, such as interprofessional communication and collaboration, interdependence of actions and user-centered care. During the course of the pandemic, a predominance of managerial rationality was noted, with a greater focus on case screening and monitoring activities and clinical-assistance support to the detriment of technical-pedagogical support to Primary Care (PC) teams, characterizing an underutilization of the potential of the multiprofessional team within the scope of Primary Health Care.

RESUMO O objetivo deste artigo é identificar as estratégias para organização e os desafios operacionais para efetivar o processo de trabalho multiprofissional das equipes do Núcleo Ampliado de Saúde da Família e Atenção Básica (Nasf-AB) no contexto da pandemia da Covid-19 no Brasil. Trata-se de estudo de revisão integrativa nas bases de dados Lilacs, Science Direct, PubMed, Biblioteca Virtual em Saúde (BVS), Scientific Electronic Library Online (SciELO), Scholar Google e revisão documental de publicações técnicas (protocolos, notas técnicas, ofícios, portarias) no site oficial do Ministério da Saúde do Brasil. Foram incluídos 13 estudos e não foram localizados documentos técnicos publicados pelo Ministério da Saúde que tratassem diretamente sobre a reorganização do processo de trabalho do Nasf-AB durante a pandemia. Evidenciou-se que os elementos que compõem o processo de trabalho em equipe foram modificados, tais como comunicação e colaboração interprofissional, interdependência das ações e atenção centrada no usuário. No curso da pandemia, notou-se uma predominância da racionalidade gerencial, com maior foco em atividades de rastreio e monitoramento de casos e apoio clínico-assistencial, em detrimento de apoio técnico-pedagógico às equipes de AB, caracterizando um subaproveitamento das potencialidades da equipe multiprofissional no âmbito da Atenção Primária à Saúde.

https://doi.org/10.1590/0103-1104202313918

14.

Teaching and learning strategies in Home Enteral Nutritional Therapy: Knowledge gains perceived by caregivers
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Afonso, Maria Gabriela

; Arroyo, Luiz Henrique

; Gastaldi, Amanda Adabo

; Assalin, Ana Carolina Belmonte

; Yamamura, Mellina

; Girão, Fernanda Berchelli

Revista Latino-Americana de Enfermagem

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dec 2023, Volume 31 elocation e3888

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective: to evaluate how different educational strategies contribute to knowledge gains perceived by caregivers of people using Enteral Nutritional Therapy. Method: a quasi-experimental study conducted in two stages: the first one included an interactive lecture class (LC) and the second was carried out in two groups: in-situ simulated skills training (ST) and reading of an educational booklet (EB). The caregivers answered a self-administered questionnaire to assess knowledge before and after the interventions; for the analysis, a generalized linear model with Poisson distribution was proposed and the comparisons were carried out using orthogonal contrasts. Results: the participants were 30 caregivers; evidence of a difference in knowledge between the t1and t0 moments is evidenced. The analysis of the final comparison about the knowledge gain between the EB and ST groups, according to Student’s t, evidenced an estimated difference of -1,33, with 95% CI (-4.98; 2.31) and p-value=0.46. Conclusion: knowledge was further increased between the t1 and t0 moments, when compared to the t2 and t1 moments in both groups. When compared, we cannot conclude that one of the groups changed more than the other in relation to moment t0 and t2; thus, the study evidenced the knowledge gain after all the educational strategies in both groups.

Resumen Objetivo: evaluar cómo las diferentes estrategias educativas contribuyen a la adquisición de conocimiento percibida por los cuidadores de personas que utilizan Terapia Nutricional Enteral. Método: estudio cuasiexperimental realizado en dos etapas; la primera incluyó una clase expositiva dialogada (CE) y la segunda se desarrolló en dos grupos: entrenamiento de habilidades (EH) simuladas in situ y lectura del folleto educativo (FE). Los cuidadores respondieron un cuestionario autoadministrado para evaluar el conocimiento pre-posintervenciones; para el análisis se propuso un modelo lineal generalizado con distribución de Poisson y las comparaciones se realizaron mediante contrastes ortogonales. Resultados: participaron 30 cuidadores, había evidencias de la diferencia de conocimiento entre los tiempos t1 y t0. El análisis de la comparación final sobre el aumento de conocimientos entre los grupos FE y EH, mediante la prueba t de Student, mostró una diferencia estimada de -1,33, con un IC del 95% (-4,98; 2,31) y un valor de p de 0,46. Conclusión: hubo un mayor aumento del conocimiento entre los tiempos t1 y t0, que entre los tiempos t2 y t1 en ambos grupos. Al compararlos, no podemos concluir que uno de los grupos cambió más que el otro entre t0 y t2; por lo tanto, el estudio demostró que hubo adquisición de conocimiento después de todas las estrategias educativas en ambos grupos.

Resumo Objetivo: avaliar como diferentes estratégias educativas contribuem para ganhos de conhecimento percebidos por cuidadores de pessoas em uso da Terapia Nutricional Enteral. Método: estudo quase-experimental realizado em duas etapas; a primeira contemplou uma aula expositiva dialogada (AE) e a segunda aconteceu em dois grupos: treino de habilidades (TH) simulado in situ e leitura da cartilha educativa (CE). Os cuidadores responderam um questionário autoaplicável para avaliação de conhecimentos em pré e pós-intervenções; para a análise foi proposto um modelo linear generalizado com distribuição Poisson e as comparações foram realizadas por contrastes ortogonais. Resultados: participaram 30 cuidadores, observou-se evidência de diferença de conhecimento entre os tempos t1 e t0. A análise da comparação final sobre o aumento do conhecimento entre os grupos CE e TH, por teste t-Student, evidenciou uma diferença estimada de -1,33, com IC 95% (-4,98; 2,31) e valor de p de 0,46. Conclusão: ocorreu uma maior elevação de conhecimento entre os tempos t1 e t0, quando comparada os tempos t2 e t1 em ambos os grupos. Quando comparados, não podemos concluir que um dos grupos mudou mais que o outro em relação aos tempos t0 e t2; assim, o estudo evidenciou o ganho de conhecimento após todas as estratégias educativas nos dois grupos.

https://doi.org/10.1590/1518-8345.6032.3888

15.

Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023
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Almeida, André Luiz Cerqueira

; Melo, Marcelo Dantas Tavares de

; Bihan, David Costa de Souza Le

; Vieira, Marcelo Luiz Campos

; Pena, José Luiz Barros

; Del Castillo, José Maria

; Abensur, Henry

; Hortegal, Renato de Aguiar

; Otto, Maria Estefania Bosco

; Piveta, Rafael Bonafim

; Dantas, Maria Rosa

; Assef, Jorge Eduardo

; Beck, Adenalva Lima de Souza

; Santo, Thais Harada Campos Espirito

; Silva, Tonnison de Oliveira

; Salemi, Vera Maria Cury

; Rocon, Camila

; Lima, Márcio Silva Miguel

; Barberato, Silvio Henrique

; Rodrigues, Ana Clara

; Rabschkowisky, Arnaldo

; Frota, Daniela do Carmo Rassi

; Gripp, Eliza de Almeida

; Barretto, Rodrigo Bellio de Mattos

; Silva, Sandra Marques e

; Cauduro, Sanderson Antonio

; Pinheiro, Aurélio Carvalho

; Araujo, Salustiano Pereira de

; Tressino, Cintia Galhardo

; Silva, Carlos Eduardo Suaide

; Monaco, Claudia Gianini

; Paiva, Marcelo Goulart

; Fisher, Cláudio Henrique

; Alves, Marco Stephan Lofrano

; Grau, Cláudia R. Pinheiro de Castro

; Santos, Maria Veronica Camara dos

; Guimarães, Isabel Cristina Britto

; Morhy, Samira Saady

; Leal, Gabriela Nunes

; Soares, Andressa Mussi

; Cruz, Cecilia Beatriz Bittencourt Viana

; Guimarães Filho, Fabio Villaça

; Assunção, Bruna Morhy Borges Leal

; Fernandes, Rafael Modesto

; Saraiva, Roberto Magalhães

; Tsutsui, Jeane Mike

; Soares, Fábio Luis de Jesus

; Falcão, Sandra Nívea dos Reis Saraiva

; Hotta, Viviane Tiemi

; Armstrong, Anderson da Costa

; Hygidio, Daniel de Andrade

; Miglioranza, Marcelo Haertel

; Camarozano, Ana Cristina

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Siqueira, Maria Eduarda Menezes de

; Torreão, Jorge Andion

; Rochitte, Carlos Eduardo

; Felix, Alex

Arquivos Brasileiros de Cardiologia

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dec 2023, Volume 120 N. 12 elocation e20230646

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230646

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