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Effects of thermal processing on nutritional composition and toxicity of jackfruit seeds
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Nascimento, Pedro César Andrade do

; Lopes, Melissa Moser de Araújo

; Stamford, Thayza Christina Montenegro

; Leão, Viviane Lansky Xavier de Souza

; Ribeiro, Marisilda de Almeida

; Vasconcelos, Margarida Angélica da Silva

Ciência Rural

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2024, Volume 54 N. 4 elocation 20230111

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: This study evaluated the impacts of thermal processing on the chemical composition of jackfruit seeds and their toxicity. The ash content of the seeds subjected to roasting was higher (3.21%) compared to the seeds in the other treatments. However, the contents of moisture (5.29%) and protein (10.49%) were lower. The protein content showed a significant difference (P≤ 0.05) among the studied groups (10.49%). The lipid content was lower in the seeds subjected to cooking (1.13%), while the carbohydrate content showed a significant difference (P≤ 0.05) among the groups studied (54.11%). Raw seeds had the highest fiber content (25.20%). Regarding toxicity, only the cooked jackfruit seed flour showed cytotoxic potential. However, none of the samples caused irritation or vascular disorders in fertilized eggs. These results suggested that heat treatment can ensure the safety of seeds against cytotoxicity; although, it reduces the content of some macronutrients.

RESUMO: Este estudo teve como objetivo avaliar os impactos do processamento térmico na composição química das sementes de jaca sua toxicidade. O teor de cinzas das sementes submetida à torra foi maior (3,21%) em comparação com as sementes nos outros tratamentos. No entanto, os teores de umidade (5,29%) e proteínas (10,49%) foram menores. O teor de proteínas apresentou diferença significativa (P≤ 0.05) entre os grupos estudados (10,49%). O teor de lipídeos foi menor nas sementes submetidas ao cozimento (1,13%), enquanto o teor de carboidratos apresentou diferença significativa (P ≤ 0.05) entre os grupos estudados (54,11%). As sementes brutas apresentaram o maior teor de fibras (25,20%). Em relação à toxicidade, apenas a farinha de sementes de jaca cozidas apresentou potencial citotóxico, embora nenhuma das amostras tenha causado irritação ou distúrbios vasculares em ovos fecundados. Esses resultados sugerem que o tratamento térmico pode garantir a segurança das sementes frente à citotoxicidade, embora reduza o teor de alguns macronutrientes.

https://doi.org/10.1590/0103-8478cr20230111

Desenvolvimento de um design de telessimulação para o suporte básico de vida
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Bernardinelli, Fabiana Cristina Pires

; Amorim, Gustavo Correa de

; Nascimento, Juliana da Silva Garcia

; Fonseca, Luciana Mara Monti

; Domingues, Tânia Arena Moreira

; Condeles, Paulo César

; Chavaglia, Suzel Regina Ribeiro

Acta Paulista de Enfermagem

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2024, Volume 37 elocation eAPE00021

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective To construct and validate a synchronous and observational telesimulation design in nursing for care according to in-hospital basic life support protocol for adults. Methods A methodological study based on the phases of the theoretical procedure carried out through a scoping review; empirical phase developed through the telesimulated design content validity and analytical phase in which the content validity index was adopted. Results A care design was constructed according to the basic life support protocol, going through six steps: planning, preparation, participation, teledebriefing, assessment and feedback and additional learning, with a Content Validity Index of 0.96. Conclusion The developed design was considered valid in content to plan and execute telesimulation by nursing and still be adapted to other educational contexts.

Resumen Objetivo Elaborar y validar un diseño de telesimulación sincrónica y observacional de enfermería para la atención de acuerdo con el protocolo de soporte vital básico intrahospitalario en adultos. Métodos Estudio metodológico basado en las fases del procedimiento teórico realizado por medio de una scoping review, fase empírica llevada cabo a través de la validación de contenido del diseño telesimulado y fase analítica en la que se adoptó el índice de validez de contenido. Resultados Se elaboró un diseño para la atención de acuerdo con el protocolo de soporte vital básico que atravesó seis etapas: planificación, preparación, participación, teledebriefing, evaluación y feedback y aprendizaje adicional, con un Índice de Validez de Contenido de 0,96. Conclusión El diseño elaborado fue considerado válido en contenido para planificar y ejecutar la telesimulación por parte de enfermeros y además puede adaptarse a otros contextos educativos.

Resumo Objetivo Construir e validar um design de telessimulação síncrona e observacional em enfermagem para o atendimento segundo o protocolo de suporte básico de vida intra-hospitalar no adulto. Métodos Estudo metodológico baseado nas fases do procedimento teórico realizado por meio de uma scoping review; fase empírica desenvolvida através da validação de conteúdo do design telessimulado e fase analítica em que adotou-se o índice de validade de conteúdo. Resultados Construiu-se um design para o atendimento segundo o protocolo de suporte básico de vida percorrendo seis etapas: o planejamento, preparação, participação, teledebriefing, avaliação e feedback e a aprendizagem adicional, com Índice de Validade de Conteúdo de 0,96. Conclusão O design desenvolvido foi considerado válido em conteúdo para planejar e executar a telessimulação pela enfermagem e ainda ser adaptado a outros contextos educacionais.

https://doi.org/10.37689/acta-ape/2024ao0000021

El plano de la expresión pasional en el cine: análisis de la película Elena
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Lopes, Joyce do Nascimento

; González Ochoa, César

Tópicos del Seminario

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dec 2023, N. 50 Pages 77 - 92

Abstract: Es Fr En | Text: Es Fr En | PDF: Es | PDF: Fr | PDF: En

Resumen A partir de la semiótica francesa, pretendemos analizar el plano expresivo de la película brasileña Elena (2012), dirigida por Petra Costa. Basada en hechos de la vida de la directora, la obra es una experiencia íntima y personal que materializa su relación con la memoria de su hermana, Elena, cuya historia estuvo marcada por un trágico hecho. El largometraje, entonces, revela un universo particular, construido a través de los afectos para generar ciertos efectos de sentido. Así, a lo largo de nuestro estudio, comprobamos cómo la afectividad, la pasión y la subjetividad impregnan la realización fílmica en su manifestación, y establecen un tono pasional que media las relaciones entre enunciador y enunciatario, que acerca estos actantes de la enunciación para movilizar afectivamente al espectador. Por lo tanto, nuestro objetivo es contribuir a la investigación analítica sobre el cine, que todavía provoca desafíos en el ámbito de las teorías del discurso.

Résumé En nous appuyant sur la sémiotique française, nous nous proposons d'analyser le plan expressif du film brésilien Elena (2012), réalisé par Petra Costa. Basé sur des événements de la vie de la réalisatrice, le film est une expérience intime et personnelle qui matérialise sa relation avec la mémoire de sa sœur, Elena, dont l'histoire a été marquée par un événement tragique. Le long métrage révèle donc un univers particulier, construit par les affects pour générer certains effets de sens. Ainsi, tout au long de notre étude, nous avons vu comment l'affectivité, la passion et la subjectivité imprègnent le cinéma dans sa manifestation et établissent une tonalité passionnelle qui médiatise les relations entre énonciateur et énonciataire, rapprochant ces actants de l'énonciation afin de mobiliser affectivement le spectateur. Par conséquent, notre objectif est de contribuer à la recherche analytique sur le film, qui suscite encore des défis dans le domaine des théories du discours.

Abstract Based on French semiotics, we aim to analyze the expression plane of the Brazilian film Elena (2012), directed by Petra Costa. Based on events from the director's life, the work is an intimate and personal experience that materializes her relationship with the memory of her sister, Elena, whose story was marked by a tragic event. The feature film, then, reveals a particular universe, built through affections to generate certain meaning effects. So, throughout our study, we verified how affectivity, passion and subjectivity permeate the filmic realization in its manifestation, establishing a passionate tone that mediates the relations between enunciator and enunciate, approaching these actants of the enunciation in order to affectively mobilize the viewer. Thus, we aim to contribute to analytical research on cinema, which still proves to be quite challenging in the scope of discourse theories.

Dificuldades de Cessação do Tabagismo: Um Estudo Netnográfico
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Brasil, Christina César Praça

; Melo, Juliana Carneiro

; Oliveira, Denise Nunes

; Nascimento, Fabiana Neiva Veloso

; Gomes, Beatriz Vasconcelos Lima

; Brasil, Thiago Praça

New Trends in Qualitative Research

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oct 2023, Volume 18 elocation e901

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: O tabagismo é um problema de saúde pública mundial, sendo um dos maiores fatores de risco responsáveis pela morte evitável. Sua aceitabilidade entre os jovens é crescente, especialmente após a chegada dos cigarros eletrônicos, que têm se tornado mais aceitos que os cigarros convencionais. Sabendo disso e que as tecnologias eletrônicas são úteis no contexto do combate ao tabagismo e no fornecimento informações sobre os prejuízos do ato de fumar, fazem-se essenciais estudos sobre como o tema é discutido nas redes de apoio virtuais. Objetivos: Identificar e compreender as dificuldades enfrentadas por tabagistas que procuram apoio para a cessação do hábito na rede social do aplicativo QuitNow! Métodos: Estudo netnográfico realizado em março de 2023. Foram analisados e observados, durante quatro dias, os comentários publicados pelos participantes do aplicativo QuitNow!, os quais relataram diversos aspectos relacionados às dificuldades e fatores que impactam o ato de cessar o tabagismo. Resultados: Analisaram-se 447 mensagens publicadas no fórum de discussão do aplicativo QuitNow! e, 31 delas relacionavam-se às dificuldades de cessar o tabagismo, com uma média de 8 (6,93%) mensagens diárias sobre este assunto. Os comentários foram classificados em duas temáticas para realização da análise qualitativa, sendo a maioria deles relacionados à dependência física do cigarro (n=19) e à dependência psicológica e comportamental (n=12). Conclusões: As tecnologias exercem um papel fundamental no auxílio a cessação do tabagismo, porém os participantes da rede social investigada não identificam um método eficaz para a assistência ao paciente em momentos de fissura, muitas vezes, acompanhados de ansiedade e depressão. Os conhecimentos obtidos nesta investigação podem contribuir para que os profissionais de saúde possam elaborar e implementar estratégias de comunicação em saúde mais ampliadas, além de inspirar políticas públicas, no sentido de apresentar alternativas tecnológicas ou não de apoio a cessação do tabagismo.

Abstract Introduction: Smoking is a worldwide public health problem, being one of the major risk factors responsible for preventable death. Its acceptability among young people is increasing, especially after the arrival of electronic cigarettes, which have become more accepted than conventional cigarettes. Knowing this and that electronic technologies are useful in the context of combating smoking and providing information about the damage caused by smoking, it is essential to study how this topic has been discussed in virtual support networks. Goals: Identify and understand the difficulties faced by smokers who seek support for quitting the habit on the QuitNow! app's social network. Methods: Netnographic study carried out in March 2023. There were analysed and observed, fou four days, comments published by QuitNow! participants, who reported several aspects related to the difficulties and factors that impact the act of quitting smoking. Results: There were analyzed 447 messages published in the QuitNow! application discussion forum, and 31 of them were related to difficulties in quitting smoking, with an average of 8 (6.93%) daily messages on this subject. The comments were divided into two themes for carrying out the qualitative analysis, most of them related to physical dependence on cigarettes (n=19) and psychological and behavioral dependence (n=12). Conclusions: Technologies play a fundamental role in helping to quit smoking, but the participants of the investigated social network did not identify an effective method for patient care in moments of craving, often accompanied by anxiety and depression. The knowledge obtained in this investigation can help health professionals to design and implement broader communication and health strategies and public policies, in the sense of presenting technological or non-technological alternatives to support smoking cessation.

https://doi.org/10.36367/ntqr.18.2023.e901

Reply to the letter regarding the article entitled: “Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol” entitled Access AReA study) protocol
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Cacho, Roberta de Oliveira

; Moro, Carla Heloisa Cabral

; Bazan, Rodrigo

; Guarda, Suzete Nascimento Farias da

; Pinto, Elen Beatriz

; Andrade, Suellen Mary Marinho dos Santos

; Valler, Lenise

; Almeida, Kelson James

; Ribeiro, Tatiana Souza

; Jucá, Renata Viana Brígido de Moura

; Minelli, Cesar

; Piemonte, Maria Elisa Pimentel

; Paschoal, Eric Homero Albuquerque

; Pedatella, Marco Túlio Araújo

; Pontes-Neto, Octávio Marques

; Fontana, Ana Paula

; Pagnussat, Aline de Souza

; Conforto, Adriana Bastos

Arquivos de Neuro-Psiquiatria

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jul 2023, Volume 81 N. 7 Pages 703 - 704

Abstract: En | Text: En | PDF: En

https://doi.org/10.1055/s-0043-1771266

Análise de barras de aço ancoradas na madeira utilizando adesivos estruturais
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Pigozzo, Júlio César

; Arroyo, Felipe Nascimento

; Lahr, Francisco Antonio Rocco

; Christoforo, André Luís

Ambiente Construído

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jan 2023, Volume 23 N. 1 Pages 145 - 156

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Devido ao preconceito, a madeira passa de um material de excelente aplicabilidade estrutural para um material considerado vilão do meio ambiente. Entretanto, com a utilização de madeiras de reflorestamento, a madeira vem quebrando esse paradigma e apresenta-se como um excelente material estrutural. Nas ligações estruturais desse tipo de estrutura, as barras de aço coladas têm sido amplamente utilizadas. A avaliação da resistência de ancoragem das barras de aço coladas depende do tipo de adesivo, da rugosidade da barra de aço, da superfície de aderência na região de ancoragem e da umidade da madeira, entre outros fatores que podem ser definidos e controlados no projeto. Neste trabalho, apresentam-se aspectos de projeto, técnica de aplicação, comportamento mecânico das barras de aço (diâmetros de 6,3 mm, 8 mm, 10 mm e 12,5 mm), sem galvanização, coladas com adesivos epóxi e poliuretano em peças de madeira (Pinus oocarpa e Corymbia citriodora), e as formas de ruptura quando solicitadas a esforços axiais (tração e compressão) em corpos de prova, além de abordar as técnicas de colagem e o controle de qualidade. Apresentam-se, ainda, influências das propriedades mecânicas da madeira e das principais variáveis significativas na resistência de ancoragem das barras de aço. É possível concluir que o adesivo epóxi foi a melhor opção para ser utilizada nesse tipo de aplicação.

Abstract As a result of prejudice, wood has not been considered a material with outstanding structural applicability, but rather as an environmental villain. However, with the use of reforestation wood, that paradigm is shifting, and the material is starting to be seen an excellent structural material. In structural connections involving wood, glued steel bars are widely used. The anchorage resistance evaluation of the bonded steel bars depends on the adhesive, on the steel bar roughness, the adhesion surface in the anchorage region, wood humidity among other construction factors that can be defined and controlled in the design. This paper also discusses design aspects, application techniques, the mechanical behaviour of the steel bars (diameters of 6.3 mm, 8 mm, 10 mm and 12.5 mm) without galvanizing, bonded with epoxy or polyurethane adhesives on the wooden parts (Pinus oocarpa and Corymbia citriodora) and forms of rupture when subjected to axial efforts (traction and compression) in specimens. In addition, this article also addresses bonding techniques and quality control, as well as the influence of the mechanical properties of wood and the most influential variables in the anchorage steel bars strength. The study concludes that the epoxy adhesive is the best option to be used in this type of application.

https://doi.org/10.1590/s1678-86212023000100654

Aglomerados de risco para ocorrência de hanseníase e as incapacidades em menores de 15 anos em Cuiabá: um estudo geoespacial
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Martoreli Júnior, José Francisco

; Ramos, Antônio Carlos Vieira

; Berra, Thaís Zamboni

; Nascimento, Murilo César do

; Tavares, Reginaldo Bazon Vaz

; Moura, Heriederson Sávio Dias

; Mello, Débora Falleiros de

; Alves, Josilene Dália

; Arcêncio, Ricardo Alexandre

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230006

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Este estudo teve como objetivo analisar a distribuição espacial da hanseníase e as incapacidades em menores de 15 anos de idade em Cuiabá. Métodos: Estudo ecológico realizado na cidade de Cuiabá, Mato Grosso, Brasil. A população do estudo foi composta de casos de hanseníase em menores de 15 anos notificados no Sistema de Informações de Agravos de Notificação, entre os anos de 2008 e 2018. Com base nos endereços residenciais, os casos foram georreferenciados. Na análise da distribuição espacial dos casos, foi utilizada a estimativa da densidade de Kernel e, posteriormente, aplicada a estatística de varredura espacial, espaço-temporal e variação espacial nas tendências temporais. Resultados: Foram notificados 514 casos de hanseníase em menores de 15 anos em Cuiabá, com percentual de 10,1% de casos com grau de incapacidade física 1 e 2,3% com grau de incapacidade física 2 no momento do diagnóstico. Com as técnicas de varredura espacial e espaço-temporal, foram identificados aglomerados de risco para hanseníase nas regiões norte, oeste, leste e sul de Cuiabá, e com a técnica de variação espacial nas tendências temporais foi identificado um aglomerado na região oeste de Cuiabá. Conclusão: Em Cuiabá, os casos de hanseníase em menores de 15 anos com incapacidades estavam distribuídos em toda a extensão urbana da cidade, com maior densidade de casos nas regiões norte e oeste, seguida da região leste. Os aglomerados de maior risco relativo foram identificados nas regiões leste e oeste, caracterizadas por apresentar baixo e médio níveis de renda.

ABSTRACT Objective This study aimed to analyze the spatial distribution of leprosy and disabilities in children under 15 years of age in Cuiabá. Methods Ecological study carried out in the city of Cuiabá, Mato Grosso, Brazil. The study population consisted of leprosy cases in children under 15 years old notified in the Notifiable Diseases Information System, between 2008 and 2018. Based on residential addresses, cases were georeferenced. In the analysis of the spatial distribution of the cases, the estimation of the Kernel density was used and, later, the statistics of spatial, spatio-temporal and Spatial Variation in Temporal Trends were applied. Results 514 cases of leprosy were reported in children under 15 years of age in Cuiabá, with a percentage of 10.1% of cases with degree of physical disability 1 and 2.3% with degree of physical disability 2 at the time of diagnosis. With the techniques of spatial and spatio-temporal scanning, clusters of risk for leprosy were identified in the North, West, East and South regions of Cuiabá, and with the technique of Spatial Variation in Temporal Trends, a cluster was identified in the West region of Cuiabá. Conclusion In Cuiabá, cases of leprosy in children under 15 years of age with disabilities were distributed throughout the urban area of the city, with the highest density of cases in the North and West regions, followed by the East region. The clusters with the highest Relative Risk were identified in the East and West regions, characterized by having low and medium income levels

https://doi.org/10.1590/1980-549720230006.2

Updating knowledge in estimating the genetics parameters: Multi-trait and Multi-Environment Bayesian analysis in rice
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Azevedo, Camila Ferreira

; Barreto, Cynthia Aparecida Valiati

; Suela, Matheus Massariol

; Nascimento, Moysés

; Silva Júnior, Antônio Carlos da

; Nascimento, Ana Carolina Campana

; Cruz, Cosme Damião

; Soraes, Plínio César

Scientia Agricola

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2023, Volume 80 elocation e20220056

Abstract: En | Text: En | PDF: En

ABSTRACT Among the multi-trait models selected to study several traits and environments jointly, the Bayesian framework has been a preferred tool when constructing a more complex and biologically realistic model. In most cases, non-informative prior distributions are adopted in studies using the Bayesian approach. However, the Bayesian approach presents more accurate estimates when informative prior distributions are used. The present study was developed to evaluate the efficiency and applicability of multi-trait multi-environment (MTME) models within a Bayesian framework utilizing a strategy for eliciting informative prior distribution using previous data on rice. The study involved data pertaining to rice (Oryza sativa L.) genotypes in three environments and five crop seasons (2010/2011 until 2014/2015) for the following traits: grain yield (GY), flowering in days (FLOR) and plant height (PH). Variance components, genetic and non-genetic parameters were estimated using the Bayesian method. In general, the informative prior distribution in Bayesian MTME models provided higher estimates of individual narrow-sense heritability and variance components, as well as minor lengths for the highest probability density interval (HPD), compared to their respective non-informative prior distribution analyses. More informative prior distributions make it possible to detect genetic correlations between traits, which cannot be achieved with non-informative prior distributions. Therefore, this mechanism presented to update knowledge for an elicitation of an informative prior distribution can be efficiently applied in rice breeding programs.

https://doi.org/10.1590/1678-992x-2022-0056

Comparative assessment of TiN thin films created by plasma deposition technique on the surface features of NiCr alloys for dental applications
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Cerqueira, Nicole da Costa

; Balica, Naasson Matheus Pereira

; Borges, Wênio Fhará Alencar

; Sousa, Gabriel Melo Reis de

; Pupim, Denise

; Radi, Polyana Alves

; Nascimento, Rubens Maribondo do

; Silva, António Ramos

; Silva, Lucas Filipe Martins da

; Costa, Thércio Henrique de Carvalho

; Silva, Heurison de Sousa e

; Nunes, Lívio César Cunha

; Sousa, Rômulo Ribeiro Magalhães de

; Santos, Rafaela Luiz Pereira

Matéria (Rio de Janeiro)

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2023, Volume 28 N. 1 elocation e20220257

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Surface treatment is an important technique to increase adhesion between implants and bones, improving its mechanical characteristics and consequently the patient’s comfort. Objectives: Ni-Cr alloys were the object of study in this work, with the purpose of analyzing and evaluating the effect of thin films deposition of titanium nitride via plasma, on its surface and comparing with cathodic cage (CC) and hollow cathode (HC) methods, for dental applications. Methods: Eighteen samples were prepared and the experiment was conducted in two steps: the pre-sputtering (1h, 350 °C, gases: Ar and H) and sputtering (4h, 450 °C, gases: Ar, Ni, and H). To characterize and compare the samples with those of reference, the Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD), Vickers Microhardness and wettability tests were used. Results: The results presented by SEM showed that during the surface treatment using CC, voids were formed, and using HC, the samples showed a more homogenous behavior. In microhardness tests, using a 25gf load, it was possible to observe that the HC method allowed an increase of 87% when compared to the reference and treated samples. Significance: Lastly, it can be concluded that both methods are suitable for Ni-Cr alloy surface treatment, and the HC technique, a method already used by dental professionals, presents better results due to the formation of a thicker film layer.

https://doi.org/10.1590/1517-7076-rmat-2022-0257

10.

Immunogenicity Characterization of COVID-19 Vaccines: A Systematic Review and Meta-analysis
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Vasconcelos, Zanair Soares

; Salem, Hany Abdulateif

; Veiga, Sâmia Pimenta

; Lima, Fabiola Estefany Botelho de

; Gonçalves, César Rogério da Silva

; Santos, Eliane Carvalho dos

; Brandão, Alba Regina Jorge

; Couceiro, Kátia Nascimento

; Guerra, Jorge Augusto de Oliveira

; Guerra, Maria das Graças Vale Barbosa

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0661-2021

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Immunogenicity has emerged as a challenge in the development of vaccines against coronavirus disease of 2019 (COVID-19). Immunogenicity is a determinant of the efficacy and safety of vaccines. This systematic review and associated meta-analysis summarized and characterized the immunogenicity of COVID-19 vaccines in randomized controlled trials (RCTs). Methods: Relevant RCTs were systematically sourced from different medical databases in August 2021. The risk ratios and mean differences with 95% confidence intervals were calculated. Results: Of 2,310 papers, 16 RCTs were eligible for review. These RCTs involved a total of 26,698 participants (15,292 males and 11,231 females). The pooled results showed a significant difference in the geometric mean titer between the vaccinated and control groups in favor of the vaccine group after 1 and 2 months of follow-up, for the young age group (18 - < 55y), and with different doses (P < 0.001). The difference in the older age group (>55y) was insignificant (P = 0.24). The seroconversion rate of spike neutralizing antibodies favored the vaccine groups 1 or 2 months after vaccination (P < 0.001). The seroconversion rate of the vaccine group was significantly different (P < 0.001) from that of the control group. Conclusions: Vaccination elicits immunogenicity in the follow-up period for all age groups and at low and large doses. Therefore, people should be encouraged to receive vaccines currently being offered. A boost dose has been asserted for the elderly.

https://doi.org/10.1590/0037-8682-0661-2022

11.

Aglomerados de risco para ocorrência de hanseníase e as incapacidades em menores de 15 anos em Cuiabá: um estudo geoespacial
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Martoreli Júnior, José Francisco

; Ramos, Antônio Carlos Vieira

; Berra, Thaís Zamboni

; Nascimento, Murilo César do

; Tavares, Reginaldo Bazon Vaz

; Moura, Heriederson Sávio Dias

; Mello, Débora Falleiros de

; Alves, Josilene Dália

; Arcêncio, Ricardo Alexandre

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230006

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720230006.2

12.

Lesão Miocárdica e Prognóstico em Pacientes Hospitalizados com COVID-19 no Brasil: Resultados do Registro Nacional de COVID-19
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Barbosa, Hannah Cardoso

; Martins, Maria Auxiliadora Parreiras

; Jesus, Jordana Cristina de

; Meira, Karina Cardoso

; Passaglia, Luiz Guilherme

; Sacioto, Manuela Furtado

; Bezerra, Adriana Falangola Benjamin

; Schwarzbold, Alexandre Vargas

; Maurílio, Amanda de Oliveira

; Farace, Barbara Lopes

; Silva, Carla Thais Cândida Alves da

; Cimini, Christiane Corrêa Rodrigues

; Silveira, Daniel Vitorio

; Carazai, Daniela do Reis

; Ponce, Daniela

; Costa, Emanuel Victor Alves

; Manenti, Euler Roberto Fernandes

; Cenci, Evelin Paola de Almeida

; Bartolazzi, Frederico

; Madeira, Glícia Cristina de Castro

; Nascimento, Guilherme Fagundes

; Velloso, Isabela Vasconcellos Pires

; Batista, Joanna d’Arc Lyra

; Morais, Júlia Drumond Parreiras de

; Carvalho, Juliana da Silva Nogueira

; Ruschel, Karen Brasil

; Martins, Karina Paula Medeiros Prado

; Zandoná, Liege Barella

; Menezes, Luanna Silva Monteiro

; Kopittke, Luciane

; Castro, Luís César de

; Nasi, Luiz Antônio

; Floriani, Maiara Anschau

; Souza, Maíra Dias

; Carneiro, Marcelo

; Bicalho, Maria Aparecida Camargos

; Lima, Maria Clara Pontello Barbosa

; Godoy, Mariana Frizzo de

; Guimarães-Júnior, Milton Henriques

; Mendes, Paulo Mascarenhas

; Delfino-Pereira, Polianna

; Ribeiro, Raquel Jaqueline Eder

; Finger, Renan Goulart

; Menezes, Rochele Mosmann

; Francisco, Saionara Cristina

; Araújo, Silvia Ferreira

; Oliveira, Talita Fischer

; Oliveira, Thainara Conceição de

; Polanczyk, Carisi Anne

; Marcolino, Milena Soriano

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 2 elocation e20220151

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Cardiovascular complications of COVID-19 are important aspects of the disease’s pathogenesis and prognosis. Evidence on the prognostic role of troponin and myocardial injury in Latin American hospitalized COVID-19 patients is still scarce. Objectives To evaluate myocardial injury as independent predictor of in-hospital mortality and invasive mechanical ventilation support in hospitalized patients, from the Brazilian COVID-19 Registry. Methods This cohort study is a substudy of the Brazilian COVID-19 Registry, conducted in 31 Brazilian hospitals of 17 cities, March-September 2020. Primary outcomes included in-hospital mortality and invasive mechanical ventilation support. Models for the primary outcomes were estimated by Poisson regression with robust variance, with statistical significance of p<0.05. Results Of 2,925 patients (median age of 60 years [48-71], 57.1% men), 27.3% presented myocardial injury. The proportion of patients with comorbidities was higher among patients with cardiac injury (median 2 [1-2] vs. 1 [0-2]). Patients with myocardial injury had higher median levels of brain natriuretic peptide, lactate dehydrogenase, creatine phosphokinase, N-terminal pro-brain natriuretic peptide, and C-reactive protein than patients without myocardial injury. As independent predictors, C-reactive protein and platelet counts were related to the risk of death, and neutrophils and platelet counts were related to the risk of invasive mechanical ventilation support. Patients with high troponin levels presented a higher risk of death (RR 2.03, 95% CI 1.60-2.58) and invasive mechanical ventilation support (RR 1.87, 95% CI 1.57-2.23), when compared to those with normal troponin levels. Conclusion Cardiac injury was an independent predictor of in-hospital mortality and the need for invasive mechanical ventilation support in hospitalized COVID-19 patients.

Resumo Fundamento As complicações cardiovasculares da COVID-19 são aspectos importantes da patogênese e do prognóstico da doença. Evidências do papel prognóstico da troponina e da lesão miocárdica em pacientes hospitalizados com COVID-19 na América Latina são ainda escassos. Objetivos Avaliar a lesão miocárdica como preditor independente de mortalidade hospitalar e suporte ventilatório mecânico em pacientes hospitalizados, do registro brasileiro de COVID-19. Métodos Este estudo coorte é um subestudo do registro brasileiro de COVID-19, conduzido em 31 hospitais brasileiros de 17 cidades, de março a setembro de 2020. Os desfechos primários incluíram mortalidade hospitalar e suporte ventilatório mecânico invasivo. Os modelos para os desfechos primários foram estimados por regressão de Poisson com variância robusta, com significância estatística de p<0,05. Resultados Dos 2925 pacientes [idade mediana de 60 anos (48-71), 57,1%], 27,3% apresentaram lesão miocárdica. A proporção de pacientes com comorbidades foi maior nos pacientes com lesão miocárdica [mediana 2 (1-2) vs. 1 (0-20)]. Os pacientes com lesão miocárdica apresentaram maiores valores medianos de peptídeo natriurético cerebral, lactato desidrogenase, creatina fosfoquinase, N-terminal do pró-peptídeo natriurético tipo B e proteína C reativa em comparação a pacientes sem lesão miocárdica. Como fatores independentes, proteína C reativa e contagem de plaquetas foram relacionados com o risco de morte, e neutrófilos e contagem de plaquetas foram relacionados ao risco de suporte ventilatório mecânico invasivo. Os pacientes com níveis elevados de troponina apresentaram um maior risco de morte (RR 2,03, IC95% 1,60-2,58) e suporte ventilatório mecânico (RR 1,87;IC95% 1,57-2,23), em comparação àqueles com níveis de troponina normais. Conclusão Lesão cardíaca foi um preditor independente de mortalidade hospitalar e necessidade de suporte ventilatório mecânico em pacientes hospitalizados com COVID-19.

https://doi.org/10.36660/abc.20220151

13.

Computational intelligence to study the importance of characteristics in flood-irrigated rice
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Silva Júnior, Antônio Carlos da

; Sant’Anna, Isabela Castro

; Silva, Gabi Nunes

; Cruz, Cosme Damião

; Nascimento, Moysés

; Lopes, Leonardo Bhering

; Soares, Plínio César

Acta Scientiarum. Agronomy

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2023, Volume 45 elocation e57209

Abstract: En | Text: En | PDF: En

ABSTRACT. The study of traits in crops enables breeders to guide strategies for selecting and accelerating the progress of genetic breeding. Although the simultaneous evaluation of characteristics in the plant breeding programme provides large quantities of information, identifying which phenotypic characteristic is the most important is a challenge facing breeders. Thus, this work aims to quantify the best approaches for prediction and establish a network of better predictive power in flood-irrigated rice via methodologies based on regression, artificial intelligence, and machine learning. Multiple regression, computational intelligence, and machine learning were used to predict the importance of the characteristics. Computational intelligence and machine learning were notable for their ability to extract nonlinear information from model inputs. Predicting the relative contribution of auxiliary characteristics in rice through computational intelligence and machine learning proved to be efficient in determining the relative importance of variables in flood-irrigated rice. The characteristics indicated to assist in decision making are flowering, number of grains filled by panicles and length of panicles for this study. The network with only one hidden layer with 15 neurons was observed to be efficient in determining the relative importance of variables in flooded rice.

https://doi.org/10.4025/actasciagron.v45i1.57209

14.

Electrochemical immunosensing of low-density lipoprotein based on sol-gel encapsulation
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Egito, Elton Max Nascimento do

; Frias, Isaac Aaron Morales

; Oliveira, Maria Danielly Lima

; Andrade, César Augusto Souza de

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e22430

Abstract: En | Text: En | PDF: En

Abstract Lipoprotein monitoring is desirable in the management of medical conditions such as atherosclerotic cardiovascular disease and coronary artery disease, in which controlling the concentration of these chylomicrons is crucial. Current clinical methods are complex and present poor reproducibility between laboratories. For these reasons, recent guidelines discard the assessment of low-density lipoprotein cholesterol (LDL-C) as a routine analysis during lipid-lowering therapies. Concerning the importance of monitoring this parameter, the authors present an electrochemical immunosensor constructed from a simple and easy-to-reproduce platform that allows detecting and quantifying LDL nanoparticles directly from human serum samples. The performance of the biosensor was studied by scanning electron microscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. The biosensing platform displays good stability and linearity between 30 mg dL-1 and 135 mg dL-1 with a detection limit of 20 mg dL-1. The proposed biosensor can be easily employed for monitoring LDL concentration in clinical treatments.

https://doi.org/10.1590/s2175-97902023e22430

15.

Oregano extract (Origanum vulgare) in female broiler chickens of free-range strain raised in the Western Amazon
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Sandra, Iuryane de Oliveira

; Gomes, Fabio Augusto

; Freitas, Henrique Jorge de

; Santos, Francisco Glauco de Araújo

; Almeida Filho, José Aparecido

; Guamán, César Andrés Guato

; Zanfagnini, Letícia Gomes

; Nascimento, Antonia Mariana do

; Alencar, Israel Castro de

Revista Brasileira de Saúde e Produção Animal

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2023, Volume 24 elocation 20220032

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT This study aimed to evaluate the effect of oregano extract added to commercial diets on zootechnical performance parameters, carcass yield, immunological conditions, morphometry, and intestinal pH for free-range broiler chickens raised under sanitary challenge conditions. Three hundred chicks of the strain ‘Heavy red’ were used and distributed in a completely randomized experimental design with five treatments and six replications, totaling 30 experimental units, each consisting of 10 birds. The treatments were: T1: Basal diet without oregano extract (OE); T2: Basal diet with OE (150 mg/kg); T3: Basal diet with OE (250 mg/kg); T4: Basal diet with OE (350 mg/kg); T5: and Basal diet with OE (450 mg/kg). There was a significant effect on feed intake, weight gain, feed conversion, feed efficiency, heterophil/lymphocyte ratio (H/L), and intestinal morphometry. No significant differences were observed in viability, carcass yield, intestinal pH, lymphoid organs, gizzard, heart, and intestine. Oregano extract influenced the liver yield and abdominal fat of broilers. Overall, the inclusion of oregano extract at the level of 350 mg/kg provided better results.

RESUMO O objetivo desse trabalho foi avaliar o efeito do extrato de orégano adicionado à ração comercial, considerando os parâmetros de desempenho zootécnico, rendimento de carcaça, condições imunológicas, morfometria e pH intestinal de frangos de corte de linhagem caipira, criados sob condição de desafio sanitário. Foram utilizados 300 pintos da linhagem vermelho pesadão, que foram distribuídos em um delineamento experimental inteiramente casualizado - DIC, com cinco tratamentos e seis repetições, totalizando 30 unidades experimentais, constituídas por 10 aves cada. Os tratamentos foram: T1: Ração basal, sem Extrato de Orégano (EO); T2: Ração basal com EO (150 mg/Kg); T3: Ração basal com EO (250 mg/Kg); T4: Ração basal com EO(350 mg/Kg); T5: Ração basal com EO (450 mg/Kg). Houve efeito significativo no consumo de ração, ganho de peso, conversão alimentar, eficiência alimentar, relação heterofilo/linfócito (H/L) e morfometria intestinal. Não foram observadas diferenças significativas na viabilidade, no rendimento de carcaça, no pH intestinal, nos órgãos linfoides, moela, coração e intestino. Promoveu influência no rendimento de fígado e gordura abdominal dos frangos. A inclusão no nível de 350mg/kg proporciona melhores resultados.

https://doi.org/10.1590/s1519-994020220032

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