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ABSTRACT Objective: This study aimed to translate, and perform a cross-cultural adaptation, and validation of the Vancouver Symptom Score (VSS) for bladder and bowel dysfunction (BBD) for Brazilian children and adolescents Materials and Methods: Six steps were performed for the translation and cross-cultural adaptation: (1) translation, (2) synthesis of translations, (3) back-translation, (4) pre-final version of the translated instrument, (5) pilot test and degree of comprehensibility and (6) elaboration of the Brazilian version of the VSS. For validation, the Brazilian Dysfunctional Voiding Score (DVSS) questionnaire was used. Results: Validation was performed on a sample of 107 children and adolescents with a mean age of 9.2 ± 2.84 years, presenting BBD and 107 without BBD (control group-CG). There was a positive correlation (r = 0.91, 95% CI 0.88 to 0.93, p < 0.0001) between total VSS score and total DVSS score. VSS was higher in patients with BBD (p < 0.0001). The internal consistency estimated by Cronbach's alpha was 0.87 for patients with BBD. The VSS showed excellent diagnostic accuracy in detecting cases, with an area under the ROC curve of 98% (95% CI 0.96 to 0.99, p < 0.001). A cut-off value of >11 points produced a sensitivity of 100% (95% CI 96.4% to 100%) and a specificity of 91.8% (95% CI 85.1% to 95.6%). Conclusion: The translated, cross-culturally adapted, and validated VSS for the Brazilian population is a reliable and valid tool to identify symptoms of BBD in children and adolescents aged five to 16 years, whose first language is Brazilian Portuguese.

https://doi.org/10.1590/s1677-5538.ibju.2022.0495

Relationship between primary monosymptomatic enuresis and process toilet training: a case-control
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Carvalho, Tânia Antunes

; Vasconcelos, Mônica Maria de Almeida

; Bessa Junior, José de

; Bastos Netto, José Murillo

; Dutra, Melissa Faria

; Guimarães, Isabela Cristina de Oliveira

; Lima, Eleonora Moreira

; Silva, Ana Cristina Simões e

; Mrad, Flávia Cristina de Carvalho

International braz j urol

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dec 2022, Volume 48 N. 6 Pages 944 - 951

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: Primary monosymptomatic nocturnal enuresis (PMNE) is a prevalent condition in childhood, and the pathophysiology is multifactorial. This study investigated the relationship between the toilet training process (TT) and PMNE in children and adolescents. Patients and Methods: A case-control study was carried out from 2015 to 2020. The presence of PMNE was identified according to International Children's Continence Society criteria. A semi-structured questionnaire was applied to assess TT. Results: The study included 103 children and adolescents with PMNE and 269 participants with normal psychomotor development without PMNE (control group [CG]). Readiness signals were more remembered and less frequent in participants with PMNE (p=0.001) when compared to control group. No differences were found between the groups regarding the onset age of the daytime TT (p= 0.10), the nocturnal TT (p=0.08), the acquisition of daytime continence (p=0.06), and the type of equipment used for the TT (p=0.99). The use of Child-Oriented approach in group of children with enuresis was lower than in controls [87.4% (90/103) versus 94% (250/266)], respectively (OR= 0.44, 95% CI 0.21-0.94, p = 0.039). Conclusions: The age of onset of TT, acquisition of daytime continence, and the type of equipment were not associated with higher occurrence of PMNE. On the other hand, the Child-Oriented approach was a protective factor for the occurrence of PMNE.

https://doi.org/10.1590/s1677-5538.ibju.2022.0381

Métodos para avaliação da efetividade de vacinas para COVID-19 com ênfase em abordagens quase-experimentais
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Pescarini, Julia Moreira

; Teixeira, Camila Silveira Silva

; Cruz, Enny Paixão

; Ortelan, Naia

; Pinto, Priscila Fernanda Porto Scaff

; Ferreira, Andrêa Jacqueline Fortes

; Alves, Flavia Jôse Oliveira

; Pinto Junior, Elzo Pereira

; Falcão, Ila Rocha

; Rocha, Aline dos Santos

; Silva, Nivea Bispo da

; Ortiz, Renzo Flores

; Saavedra, Ramon da Costa

; Oliveira, Vinicius de Araújo

; Ribeiro-Silva, Rita de Cássia

; Ichihara, Maria Yury Travassos

; Boaventura, Viviane

; Barral Netto, Manoel

; Kerr, Ligia Regina Franco Sansigolo

; Werneck, Guilherme Loureiro

; Barreto, Mauricio L.

Ciência & Saúde Coletiva

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nov 2021, Volume 26 N. 11 Pages 5599 - 5614

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A avalição da efetividade de vacinas é feita com dados do mundo real e é essencial para monitorar o desempenho dos programas de vacinação ao longo do tempo bem como frente a novas variantes. Até o momento, a avaliação da efetividade das vacinas para COVID-19 tem sido baseada em métodos clássicos como estudos de coorte e caso controle teste-negativo, que muitas vezes podem não permitir o adequado controle dos vieses intrínsecos da alocação das campanhas de vacinação. O objetivo dessa revisão foi discutir os desenhos de estudo disponíveis para avaliação de efetividade das vacinas, enfatizando os estudos quase-experimentais, que buscam mimetizar os estudos aleatorizados ao introduzir um componente exógeno para atribuição ao tratamento, bem como suas vantagens, limitações e aplicabilidade no contexto dos dados brasileiros. O emprego de métodos quase-experimentais, incluindo as séries temporais interrompidas, o método de diferença em diferenças, escore de propensão, variáveis instrumentais e regressão descontínua, são relevantes pela possibilidade de gerar estimativas mais acuradas da efetividade de vacinas para COVID-19 em cenários como o brasileiro, que se caracteriza pelo uso de várias vacinas, com respectivos número e intervalos entre doses, aplicadas em diferentes faixas etárias e em diferentes momentos da pandemia.

Abstract The evaluation of vaccine effectiveness is conducted with real-world data. They are essential to monitor the performance of vaccination programmes over time, and in the context of the emergence of new variants. Until now, the effectiveness of COVID-19 vaccines has been assessed based on classic methods, such as cohort and test-negative case-control studies, which may often not allow for adequate control of inherent biases in the assignment of vaccination campaigns. The aim of this review was to discuss the study designs available to evaluate vaccine effectiveness, highlighting quasi-experimental studies, which seek to mimic randomized trials, by introducing an exogenous component to allocate to treatment, in addition to the advantages, limitations, and applicability in the context of Brazilian data. The use of quasi-experimental approaches, such as interrupted time series, difference-in-differences, propensity scores, instrumental variables, and regression discontinuity design, are relevant due to the possibility of providing more accurate estimates of COVID-19 vaccine effectiveness. This is especially important in scenarios such as the Brazilian, which characterized by the use of various vaccines, with the respective numbers and intervals between doses, applied to different age groups, and introduced at different times during the pandemic.

https://doi.org/10.1590/1413-812320212611.18622021 1 downloads

Association between Attention Deficit Hyperactivity Disorder and lower urinary tract symptoms in children and adolescents in a community setting
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Vasconcelos, Mônica Maria de Almeida

; Bastos Netto, José Murillo

; Arana, Isaac Eduardo

; Teixeira, Isabela Benevenuto

; Lima, Eleonora Moreira

; Carvalho, Tânia Antunes

; Bessa Junior, José de

; Mrad, Flávia Cristina de Carvalho

International braz j urol

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oct 2021, Volume 47 N. 5 Pages 969 - 978

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: The present study aims to investigate the prevalence of lower tract urinary symptoms (LUTS) and symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents and their association in a community setting using validated scoring instruments. Materials and Methods: A cross-sectional study was carried out from February 2015 to December 2019, during which the parents or guardians of 431 children and adolescents from 5 to 13 years of age, attending a general pediatric outpatient clinic were interviewed. Results: The prevalence of ADHD symptoms and LUTS were 19.9% and 17.9%, respectively. Of the 82 children and adolescents with ADHD, 28% (23) had LUTS (OR 2.31, 95% CI 1.28 to 3.75, p=0.008). Mean total DVSS score in children in the group of children presenting ADHD symptom was significantly higher than those without ADHD symptom (10.2±4.85 vs. 4.9±2.95, p=0.002). Urgency prevailed among LUTS as the most frequent symptom reported by patients with ADHD symptoms (p=0.004). Analyzing all subscales of the DVSS, the items “When your child wants to pee, can't he wait? “Your child holds the pee by crossing his legs, crouching or dancing?” were higher in those with ADHD symptoms (p=0.01 and 0.02, respectively). Functional constipation was present in 36.4% of children with LUTS and 20.7% without LUTS (OR 4.3 95% CI 1-5.3 p=0.001). Conclusion: Children and adolescents with ADHD symptoms are 2.3 times more likely to have LUTS. The combined type of ADHD was the most prevalent among them.

https://doi.org/10.1590/s1677-5538.ibju.2020.0978 177 downloads

Métodos para avaliação da efetividade de vacinas para COVID-19 com ênfase em abordagens quase-experimentais
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Pescarini, Julia Moreira

; Teixeira, Camila Silveira Silva

; Cruz, Enny Paixão

; Ortelan, Naia

; Pinto, Priscila Fernanda Porto Scaff

; Ferreira, Andrêa Jacqueline Fortes

; Alves, Flavia Jôse Oliveira

; Pinto Junior, Elzo Pereira

; Falcão, Ila Rocha

; Rocha, Aline dos Santos

; Silva, Nivea Bispo da

; Ortiz, Renzo Flores

; Saavedra, Ramon da Costa

; Oliveira, Vinicius de Araújo

; Ribeiro-Silva, Rita de Cássia

; Ichihara, Maria Yury Travassos

; Boaventura, Viviane

; Barral Netto, Manoel

; Kerr, Ligia Regina Franco Sansigolo

; Werneck, Guilherme Loureiro

; Barreto, Mauricio L.

Ciência & Saúde Coletiva

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2021, Volume 26 N. 11 Pages 5599 - 5614

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212611.18622021

Medidas de distanciamento social no controle da pandemia de COVID-19: potenciais impactos e desafios no Brasil
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Aquino, Estela M. L.

; Silveira, Ismael Henrique

; Pescarini, Julia Moreira

; Aquino, Rosana

; Souza-Filho, Jaime Almeida de

; Rocha, Aline dos Santos

; Ferreira, Andrea

; Victor, Audêncio

; Teixeira, Camila

; Machado, Daiane Borges

; Paixão, Enny

; Alves, Flávia Jôse Oliveira

; Pilecco, Flávia

; Menezes, Greice

; Gabrielli, Ligia

; Leite, Luciana

; Almeida, Maria da Conceição Chagas de

; Ortelan, Naiá

; Fernandes, Qeren Hapuk R. Ferreira

; Ortiz, Renzo Joel Flores

; Palmeira, Raquel Nunes

; Pinto Junior, Elzo Pereira

; Aragão, Erika

; Souza, Luis Eugenio Portela Fernandes de

; Barral Netto, Manoel

; Teixeira, Maria Glória

; Barreto, Mauricio Lima

; Ichihara, Maria Yury

; Lima, Raíza Tourinho dos Reis Silva

Ciência & Saúde Coletiva

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jun 2020, Volume 25 Suppl. 1 Pages 2423 - 2446

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A pandemia de COVID-19 tem desafiado pesquisadores e gestores a encontrar medidas de saúde pública que evitem o colapso dos sistemas de saúde e reduzam os óbitos. Esta revisão narrativa buscou sistematizar as evidências sobre o impacto das medidas de distanciamento social na epidemia de COVID-19 e discutir sua implementação no Brasil. Foram triados artigos sobre o efeito do distanciamento social na COVID-19 no PubMed, medRXiv e bioRvix, e analisados atos do poder público nos níveis federal e estadual para sumarizar as estratégias implementadas no Brasil. Os achados sugerem que o distanciamento social adotado por população é efetivo, especialmente quando combinado ao isolamento de casos e à quarentena dos contatos. Recomenda-se a implementação de medidas de distanciamento social e de políticas de proteção social para garantir a sustentabilidade dessas medidas. Para o controle da COVID-19 no Brasil, é imprescindível que essas medidas estejam aliadas ao fortalecimento do sistema de vigilância nos três níveis do SUS, que inclui a avaliação e uso de indicadores adicionais para monitorar a evolução da pandemia e o efeito das medidas de controle, a ampliação da capacidade de testagem, e divulgação ampla e transparente das notificações e de testagem desagregadas.

Abstract The COVID-19 pandemic has challenged researchers and policy makers to identify public safety measures forpreventing the collapse of healthcare systems and reducingdeaths. This narrative review summarizes the available evidence on the impact of social distancing measures on the epidemic and discusses the implementation of these measures in Brazil. Articles on the effect of social distancing on COVID-19 were selected from the PubMed, medRXiv and bioRvix databases. Federal and state legislation was analyzed to summarize the strategies implemented in Brazil. Social distancing measures adopted by the population appear effective, particularly when implemented in conjunction with the isolation of cases and quarantining of contacts. Therefore, social distancing measures, and social protection policies to guarantee the sustainability of these measures, should be implemented. To control COVID-19 in Brazil, it is also crucial that epidemiological monitoring is strengthened at all three levels of the Brazilian National Health System (SUS). This includes evaluating and usingsupplementary indicators to monitor the progression of the pandemic and the effect of the control measures, increasing testing capacity, and making disaggregated notificationsand testing resultstransparentand broadly available.

https://doi.org/10.1590/1413-81232020256.1.10502020 73073 downloads

Medidas de distanciamento social no controle da pandemia de COVID-19: potenciais impactos e desafios no Brasil
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Aquino, Estela M. L.

; Silveira, Ismael Henrique

; Pescarini, Julia Moreira

; Aquino, Rosana

; Souza-Filho, Jaime Almeida de

; Rocha, Aline dos Santos

; Ferreira, Andrea

; Victor, Audêncio

; Teixeira, Camila

; Machado, Daiane Borges

; Paixão, Enny

; Alves, Flávia Jôse Oliveira

; Pilecco, Flávia

; Menezes, Greice

; Gabrielli, Ligia

; Leite, Luciana

; Almeida, Maria da Conceição Chagas de

; Ortelan, Naiá

; Fernandes, Qeren Hapuk R. Ferreira

; Ortiz, Renzo Joel Flores

; Palmeira, Raquel Nunes

; Pinto Junior, Elzo Pereira

; Aragão, Erika

; Souza, Luis Eugenio Portela Fernandes de

; Barral Netto, Manoel

; Teixeira, Maria Glória

; Barreto, Mauricio Lima

; Ichihara, Maria Yury

; Lima, Raíza Tourinho dos Reis Silva

Ciência & Saúde Coletiva

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2020, Volume 25 Suppl. 1 Pages 2423 - 2446

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232020256.1.10502020

Perfil de termorregulaçâo e desfecho clínico em pacientes críticos com sepse
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Corrêa, Flávia

; Menezes Silveira, Laura

; Padovani Lopes, Nátali Artal

; Ruffino-Netto, Antônio

; Stabile, Angelita Maria

Avances en Enfermería

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dec 2019, Volume 37 N. 3 Pages 293 - 302

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo: describir el perfil de la temperatura corporal (TC) y el desenlace en pacientes con sepsis asistidos en una unidad de cuidado intensivo (UCI). Método: estudio retrospectivo, descriptivo y exploratorio. Se incluyeron pacientes mayores de 18 años, diagnosticados con sepsis grave o shock séptico en el periodo de enero a diciembre de 2012, asistidos en una uci de un hospital púbico. Se construyeron variables sociodemográficas, clínicas y de desenlace. Para la evaluación de la TC se consideraron todas las medidas registradas durante la hospitalización, tomadas en la región axilar con termómetro digital acoplado al monitor multiparamétrico. Adicionalmente, se propusieron escenarios comparativos entre el número de episodios de fiebre o hipotermia en las 24 horas después del ingreso y el número de estos las 24 horas previas al desenlace. Los datos fueron recolectados de registros médicos físicos y electrónicos. Resultados: se incluyeron 105 pacientes, con predominio de mayores de 60 años, sexo masculino y color blanco. El resultado clínico para 26 pacientes (24,8 %) fue el alta y para 79 (75,2 %) la muerte. Se observaron 8778 verificaciones de TC, siendo la hipotermia más frecuente en el grupo de muerte (p = 0,00). En el grupo de alta, las medidas dentro de la normalidad fueron más frecuentes (p = 0,00). Entre los escenarios propuestos hubo diferencia estadísticamente significativa entre los grupos cuando ocurrieron dos o más episodios de fiebre en las 24 horas anteriores al desenlace. Conclusión: la descripción del perfil de termorregulación en pacientes sépticos mostró que la TC es un indicador complementario capaz de auxiliar al equipo en la práctica clínica con el objetivo de propiciar mejores resultados.

Abstract Objective: to describe the body temperature profile (TC) and the outcome in patients with sepsis assisted in an intensive care unit (UCI). Method: retrospective, descriptive and exploratory study. Patients over the age of 18 were included, diagnosed with severe sepsis or septic shock in the period from January to December 2012, assisted in an UCI of a public hospital. Sociodemographic, clinical and outcome variables were built. For the evaluation of the TC, all measures recorded during hospitalization were considered, taken in the axillary region by digital thermometer coupled to the multiparametric monitor. In addition, comparative scenarios were proposed between the number of episodes of fever or hypothermia in the 24 hours after internment and the number of these 24 hours prior to the outcome. The data were collected from physical and electronic medical records. Results: 105 patients were included, predominantly over 60 years old, male and white. Clinical outcome for 26 patients (24.8 %) was to be discharged, and for 79 (75.2 %) it was death. 8778 TC verifications were observed, being hypothermia the most frequent in the death group (p = 0.00). In the discharge group, measurements within normality were more frequent (p = 0.00). Among the proposed scenarios, there was statistically significant difference between the groups when two or more episodes of fever occurred in the 24 hours prior to the outcome. Conclusion: the description of the thermoregulation profile in septic patients showed that the TC is a complementary indicator capable of assisting the team in the clinical practice in order to promote better results.

Resumo Objetivo: descrever o perfil da temperatura corporal (TC) e o desfecho em pacientes com sepse atendidos em uma Unidade de Terapia Intensiva (UTI). Método: estudo retrospectivo, descritivo e exploratório. Incluíram-se pacientes maiores de 18 anos, diagnosticados com sepse grave ou choque séptico no período de janeiro a dezembro 2012, atendidos em uma UTI de um hospital púbico. Foram levantadas variáveis sociodemográficas, clínicas e o desfecho. Para a avaliação da TC, consideraram-se todas as medidas registradas durante a internação, aferidas na região axilar por termômetro digital acoplado ao monitor multiparamétrico. Adicionalmente, propuseram-se cenários comparativos entre o número de episódios de febre ou hipotermia nas 24 horas após a internação e nas 24 horas prévias ao desfecho. Os dados foram coletados nos prontuários físicos e eletrônicos. Resultados: foram incluídos 105 pacientes, com predominância de maiores de 60 anos, sexo masculino e cor branca. O desfecho clínico para 26 (24,8 %) foi a alta e para 79 (75,2 %), o óbito. Foram observadas 8778 verificações da TC, sendo a hipotermia mais frequente no grupo óbito (p = 0,00). No grupo alta, as medidas dentro da normalidade foram mais frequentes (p = 0,00). Entre os cenários propostos, houve diferenças estatisticamente significantes entre os grupos quando ocorreram dois ou mais episódios de febre nas 24 horas prévias ao desfecho. Conclusão: a descrição do perfil de termorregulação em pacientes sépticos mostrou que a TC é um indicador complementar capaz de auxiliar a equipe na prática clínica com intuito de propiciar melhores desfechos.

https://doi.org/10.15446/av.enferm.v37n3.77009 1741 downloads

Smoking and its association with cryptorchidism in Down syndrome
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Duarte, Adrianne Maria Berno de Rezende

; Bessa Júnior, José de

; Mrad, Flávia Cristina de Carvalho

; Tibiriçá, Sandra Helena Cerrato

; Camargo, Maíra Lorenzo de Sá

; Vieira, Augusto Alves Pinto

; Araujo, Frederico Cantarino Cordeiro

; Figueiredo, André Avarese de

; Bastos-Netto, José Murillo de

Revista da Associação Médica Brasileira

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aug 2017, Volume 63 N. 8 Pages 693 - 696

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A criptorquidia é uma condição comum e prevalente em pacientes com síndrome de Down. Fatores ambientais, como o tabagismo, estão associados a malformações fetais. A avaliação da prevalência do criptorquidismo e a associação com tabagismo dos pais na síndrome de Down podem contribuir para alertar os profissionais de saúde e familiares sobre a prevenção dos danos causados pelo criptorquidismo e os possíveis fatores predisponentes. Objetivo: Avaliar a prevalência de criptorquidismo na síndrome de Down e a associação com tabagismo materno e paterno. Método: Quarenta (40) pacientes acompanhados em um centro de referência para atendimento da síndrome de Down foram avaliados por meio de questionário semiestruturado para avaliação de antecedentes parentais e características sociodemográficas, bem como de exames físico e laboratoriais complementares. Resultados: Criptorquidia foi observada em 27,5% dos pacientes (IC95% 15,98-42,96). Nesses pacientes, o criptorquidismo foi encontrado em 55% (5/9) das crianças cujas mães fumavam e em 19,35% (6/31) daquelas cujas mães não fumavam (OR = 5,26 [IC95% 1,06-25,41]; p=0,032). Do mesmo modo, o tabagismo paterno foi observado com maior frequência entre crianças com criptorquidia, 63,36% (7/11) e 31,03% (9/29), respectivamente (OR = 3,89 [IC95% 0,91-16,73]; p=0,060). Conclusão: A prevalência de criptorquidismo é alta em pacientes com síndrome de Down. Podemos mostrar uma forte associação entre hábito tabágico dos pais e ocorrência de criptorquidismo, especialmente no caso de tabagismo materno.

Summary Introduction: Cryptorchidism is a common and prevalent condition in patients with Down syndrome. Environmental factors, such as smoking, can be associated with malformations during fetal development. The study of the prevalence of cryptorchidism and its association with parental tobacco use in Down syndrome can contribute to alert health care professionals, patients and family members regarding the prevention of the harms caused by cryptorchidism and its possible predisposing factors. Objective: To evaluate the prevalence of cryptorchidism in Down syndrome and its association with maternal and paternal smoking. Method: Forty (40) patients of a public clinic specialized in Down syndrome were evaluated, using a semi-structured questionnaire for evaluation of antecedents and sociodemographic characteristics, as well as physical and complementary examinations. Results: Cryptorchidism was observed in 27.5% of the patients (95CI 15.98-42.96). Of these, 55% (5/9) were the children of mothers who smoked during pregnancy, and 19.35% (6/31) were the children of mothers who did not smoke during pregnancy (OR = 5.26 [95CI 1.06-25.41]; p=0.032). Similarly, paternal smoking was also observed in greater frequency among the parents of cryptorchid patients compared with subjects with descended testis, 63.36% (7/11) and 31.03% (9/29), respectively (OR = 3.89 [95CI 0.91-16.73]; p=0.060). Conclusion: The prevalence of cryptorchidism is high in patients with Down syndrome. We can show a strong association between smoking parents and the occurrence of cryptorchidism, especially when it comes to maternal smoking.

https://doi.org/10.1590/1806-9282.63.08.693 1744 downloads

10.

BRS Vivi: single-cross super sweet corn hybrid
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Teixeira, Flavia França

; Paes, Maria Cristina Dias

; Gama, Elto Eugênio Gomes e

; Pereira Filho, Israel Alexandre

; Miranda, Rubens Augusto de

; Guimarães, Paulo Evaristo de Oliveira

; Parentoni, Sidney Netto

; Cotta, Luciano Viana

; Meirelles, Walter Fernandes

; Pacheco, Cleso Antonio Patto

; Guimarães, Lauro José Moreira

; Silva, Adelmo Resende da

; Machado, Jane Rodrigues de Assis

Crop Breeding and Applied Biotechnology

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jun 2014, Volume 14 N. 2 Pages 124 - 127

Abstract: En | Text: En | PDF: En

This study aims to describe the single-cross, super sweet corn hybrid BRS Vivi, with above-average ear diameter, light-colored grains and competitiveness with other sweet corn cultivars. BRS Vivi is a contribution to the expansion of the range of available cultivars on the market and the genetic basis of sweet corn in Brazil.

https://doi.org/10.1590/1984-70332014v14n2c21 1677 downloads Cited 1 time in SciELO

11.

Antioxidant capacity of amaranth products: effects of thermal and enzymatic treatments
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Pazinatto, Caroline

; Malta, Luciana Gomes

; Pastore, Gláucia Maria

; Maria Netto, Flavia

Food Science and Technology

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sep 2013, Volume 33 N. 3 Pages 485 - 493

Abstract: En | Text: En | PDF: En

The effect of different process -defatting, protein concentration, thermal treatment, hydrolysis with Alcalase and in vitro digestion- on the antioxidant capacity of amaranth seeds was studied. The antioxidant capacity of the products was determined in methanolic and aqueous extracts and varied from 1.00 to 21.22 and 4.97 to 369.18 µ mol TE/g sample for DPPH and ORAC assays, respectively. The combination of protein concentration and hydrolysis with Alcalase led to products with higher antioxidant activity. However, after in vitro digestion, protein concentrate and its hydrolysate showed similar antioxidant capacity. A high correlation was observed between the antioxidant capacity and the total phenolic content for methanolic extracts, with r² values ranging from 0.6133 to 0.9352.

4423 downloads Cited 3 times in SciELO

12.

In search of a tolerance-induction strategy for cow's milk allergies: significant reduction of beta-lactoglobulin allergenicity via transglutaminase/cysteine polymerization
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Olivier, Celso Eduardo

; Lima, Regiane Patussi dos Santos

; Pinto, Daiana Guedes

; Santos, Raquel Acacia Pereira Goncalves dos

; Silva, Grayce Katlen Moreno da

; Lorena, Sônia Letícia Silva

; Villas-Boas, Mariana Battaglin

; Netto, Flávia Maria

; Zollner, Ricardo de Lima

Clinics

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oct 2012, Volume 67 N. 10 Pages 1171 - 1179

Abstract: En | Text: En | PDF: En

OBJECTIVE: To explore the use of β-lactoglobulin polymerized using microbial transglutaminase and heating to identify whether protein polymerization could reduce in vivo allergenicity and maintain in vitro and ex vivo immunoreactivity for use in tolerance-induction protocols. METHODS: Based on previous protocols applied in mice and children, we performed in vivo challenges (using a skin prick test) with native and polymerized β-lactoglobulin in adult patients with an IgE-mediated allergy to plactoglobulin. In vitro humoral immunoreactivity was analyzed using immunoblotting. Cell-mediated immunoreactivity was analyzed using ex vivo challenges with native and polymerized β-lactoglobulin and monitored by leukocyte adherence inhibition tests. RESULTS: The skin tests demonstrated that there was a significant reduction in immediate cutaneous reactivity after polymerization. Polymerization did not decrease the immunoblotting detection of s-IgE specific to β-lactoglobulin. Cell-mediated immunoreactivity, as assessed by ex vivo challenges and leukocyte adherence inhibition tests, did not exhibit significant differences between leukocytes challenged with native versus polymerized β-lactoglobulin. CONCLUSIONS: The polymerization of β-lactoglobulin decreased in vivo allergenicity and did not decrease in vitro humoral or ex vivo cell-mediated immunoreactivity. Therefore, we conclude that inducing polymerization using transglutaminase represents a promising technique to produce suitable molecules for the purpose of designing oral/ sublingual tolerance induction protocols for the treatment of allergies.

https://doi.org/10.6061/clinics/2012(10)09 2800 downloads

13.

Inserção do acompanhante no cuidado da adolescente em um centro obstétrico do sul do país
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Melo, Jéssica Silva de

; Kerber, Nalú Pereira da Costa

; Oliveira, Adriane Maria Netto de

; Busanello, Josefine

; Silveira, Thais Serafim da

; Pohlmann, Flávia Conceição

Ciência, Cuidado & Saúde

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dec 2011, Volume 10 N. 4 Pages 781 - 788

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

This study has the goal of checking how the insertion of a relative companion of the teen mother is processed, from the discourse of the companions. It is a descriptive qualitative study, carried out through interviews with companions of young mothers, users of the Unified Health System, assisted at the obstetric center of a university hospital in southern Brazil between July 2008 and October 2009. We obtained approval from the Ethics Committee in Research under number 14/2008. After the analysis, organization and interpretation of collected data, correlations were established with studies conducted in the area. It was found that the majority of caregivers received news about the mother and baby after birth. However, this does not alleviate the concern felt by them and the need to be present during the birth process. It could be proven, in the words of the interviewees that their insertion on the care of the mother and the baby does not happen, since they cannot enter any time in the obstetric center and can see them only when both are transferred to the Inpatient Unit. The only explanation for no allowing the companion next to the mother is the inadequate physical space of obstetric center which was studied.

Este estudio tiene el objetivo de verificar cómo se procesa la inserción del familiar acompañante en el cuidado de la parturienta adolescente, a partir del relato de los propios acompañantes. Se trata de un estudio cualitativo descriptivo, realizado entre julio de 2008 y octubre de 2009, a través de entrevistas con los acompañantes de parturientas adolescentes usuarias del Sistema Único de Salud y asistidas en el centro obstétrico de un hospital universitario del Sur de Brasil. Se obtuvo la aprobación del Comité de Ética en Investigación, bajo el número 14/2008. Tras el análisis, organización e interpretación de los datos recogidos, se han establecido correlaciones con otros estudios desarrollados en el área. Se constató que gran parte de los acompañantes recibió noticias sobre la parturienta y el bebé después del nacimiento. Sin embargo, esto no alivió la preocupación que sentían y la necesidad de estar presentes durante el proceso de parto. Se pudo comprobar, por las hablas de los entrevistados, que la inserción de ellos en el cuidado de la madre y del bebé no sucede porque no pueden entrar en ningún momento en el centro obstétrico. Los acompañantes pueden ver solamente cuando ambos se trasladan a la unidad de hospitalización. La única justificativa extraída de los testimonios para no permitirse que el acompañante permanezca al lado de la madre es la insuficiencia de espacio físico del centro obstétrico investigado.

Este estudo objetivou verificar como se processa a inserção do familiar acompanhante no cuidado da parturiente adolescente, a partir do relato dos próprios acompanhantes. De caráter qualitativo e descritivo, foi realizado entre julho de 2008 e outubro de 2009 por meio de entrevistas com os acompanhantes de parturientes adolescentes usuárias do Sistema Único de Saúde e assistidas no centro obstétrico de um hospital universitário do Sul do Brasil. Obteve-se autorização do competente Comitê de Ética em Pesquisa, sob o número 14/2008. Após a análise, organização e interpretação dos dados coletados, estabeleceram-se correlações com estudos desenvolvidos na área. Constatou-se que grande parte dos acompanhantes recebeu notícias sobre a parturiente e o bebê após o nascimento, porém isto não amenizou sua preocupação e a necessidade de estarem presentes durante o processo de parto. Pode-se comprovar, pelas falas dos entrevistados, que a inserção destes no cuidado da parturiente e do bebê não aconteceporque não podem entrar em nenhum momento no centro obstétrico. Os acompanhantes podem vê-los somente quando ambos são transferidos para a unidade de internação.A única justificativa extraída dos depoimentos para não se permitir que o acompanhante fique junto à parturiente é o inadequado espaço físico do centro obstétrico pesquisado.

4 downloads Cited 1 time in SciELO

14.

Elaboration of sausage using minced fish of Nile tilapia filleting waste
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Oliveira Filho, Paulo Roberto Campagnoli de

; Maria Netto, Flavia

; Ramos, Kazumi Kawazaki

; Trindade, Marco Antônio

; Viegas, Elisabete Maria Macedo

Brazilian Archives of Biology and Technology

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dec 2010, Volume 53 N. 6 Pages 1383 - 1391

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objetivo deste estudo foi avaliar a inclusão de carne mecanicamente separada (CMS) (0, 20, 40, 60, 80 e 100%), obtido de resíduos de filetagem de tilápias do Nilo, em salsichas e determinar suas propriedades físico-químicas, nutricionais e sensoriais. As salsichas apresentaram diminuição de proteína e aumento de lipídeos com a inclusão de CMS. A qualidade nutricional dos produtos foi alta, com digestibilidade acima de 85%. Os parâmetros de textura e cor instrumental amarela (b*) diminuíram com inclusão crescente de CMS. A avaliação sensorial da cor mostrou que o nível máximo de inclusão de CMS não foi bem aceito pelos provadores. As salsichas com melhor aceitação do atributo sabor foram aquelas com 60% de CMS. Os resultados demonstraram a boa qualidade nutricional das salsichas utilizando CMS de resíduos de filetagem de tilápias do Nilo e de acordo com avaliação sensorial, a porcentagem máxima de inclusão é de 60%.

The objective of this study was to evaluate the inclusion of minced fish (MF) (0, 20, 40, 60, 80 and 100%), obtained from Nile tilapia filleting waste, in sausage and determine their physicochemical, nutritional and sensory properties. The sausages showed a decrease in protein and increase in fat content with increasing inclusion of MF. The nutritional quality of the products was high, with digestibility over 85%. The parameters of texture instrumental and yellow color (b*) decreased with the increasing inclusion of MF. The sensory evaluation of the color showed that the maximum level of inclusion of MF was not well accepted by the panelists. The sausage with the best acceptance for the flavor attribute was those with 60% of MF. The results showed good nutritional quality of sausages utilizing MF of Nile tilapia filleting waste and according to the sensory evaluation, the maximum level of inclusion should not exceed 60%.

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15.

Marine Pseudomonas putida: a potential source of antimicrobial substances against antibiotic-resistant bacteria
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Marinho, Palloma Rodrigues

; Moreira, Ana Paula Barbosa

; Pellegrino, Flávia Lúcia Piffano Costa

; Muricy, Guilherme

; Bastos, Maria do Carmo de Freire

; Santos, Kátia Regina Netto dos

; Giambiagi-deMarval, Marcia

; Laport, Marinella Silva

Memórias do Instituto Oswaldo Cruz

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aug 2009, Volume 104 N. 5 Pages 678 - 682

Abstract: En | Text: En | PDF: En

Bacteria isolated from marine sponges found off the coast of Rio de Janeiro, Brazil, were screened for the production of antimicrobial substances. We report a new Pseudomonas putida strain (designated P. putida Mm3) isolated from the sponge Mycale microsigmatosa that produces a powerful antimicrobial substance active against multidrug-resistant bacteria. P. putida Mm3 was identified on the basis of 16S rRNA gene sequencing and phenotypic tests. Molecular typing for Mm3 was performed by RAPD-PCR and comparison of the results to other Pseudomonas strains. Our results contribute to the search for new antimicrobial agents, an important strategy for developing alternative therapies to treat infections caused by multidrug-resistant bacteria.

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