Search | SciELO

ABSTRACT This study aimed to analyze the impacts of the social isolation resulting from the COVID-19 pandemic on family life, with emphasis on the experience of motherhood and the relationship with children. Twenty mothers from the middle social strata, from 29 to 45 years old, who kept working activities at a distance and were in social isolation, participated. In-depth individual interviews were conducted by digital means. The collected material was transcribed and submitted to thematic content analysis. The results showed that the changes imposed by the pandemic directly impacted family life, highlighting gender inequalities in routine organization, distribution of household tasks and parental care. An ambivalent relationship was observed between mothers and maternity and their social imperatives, which reverberated in the bond they establish with their children. The analysis reveals that emotional and physical burden contributes to exacerbate feelings of guilt and loneliness experienced in the relationship with motherhood, in addition to showing conflicts in the performance of the roles of mother, wife and professional. The women interviewed showed exhaustion with domestic and child care demands, in addition to conflicts related to the mismatch between expectations and social standards that regulate the exercise of motherhood and their personal experiences as mothers. The conclusions suggest the presence of an identity crisis due to the social ideals linked to the experiences of motherhood, which invites us to think about the urgency of looking at maternal suffering, seeking to understand the subjective dimensions of the transformations that this experience goes through in the times of social isolation.

RESUMEN El objetivo de este estudio fue analizar los efectos del aislamiento social resultante de la pandemia de COVID-19 en la vida familiar, con énfasis en la experiencia de la maternidad y la relación con los niños. Participaron 20 madres de estratos sociales medios, de 29 a 45 años de edad, que mantenían actividades laborales a distancia y se encontraban en aislamiento social. Se realizaron entrevistas individuales exhaustivas por medios digitales. El material recopilado se transcribió y se sometió a un análisis de contenido temático. Los resultados mostraron que los cambios impuestos por la pandemia afectaban directamente a la vida familiar, lo que explicaba las desigualdades de género en la organización rutinaria, la distribución de las tareas domésticas y el cuidado de los niños. Se observó una relación ambivalente entre las madres y la maternidad y sus imperativos sociales, que reverberaban en el vínculo que establecen con sus hijos. El análisis revela que la sobrecarga emocional y física contribuye a exacerbar los sentimientos de culpa y soledad experimentados en la relación con la maternidad, además de mostrar conflictos en el desempeño de los papeles de madre, esposa y profesional. Las mujeres entrevistadas mostraron agotamiento con las demandas domésticas y el cuidado de sus hijos, además de conflictos relacionados con el desajuste entre las expectativas y las normas sociales que regulan el ejercicio de la maternidad y sus experiencias personales como madres. Las conclusiones sugieren la presencia de una crisis de identidad ligada a los ideales sociales vinculados a las experiencias de la maternidad, lo que invita a pensar en la urgencia de mirar el sufrimiento materno, tratando de comprender las dimensiones subjetivas de las transformaciones en tiempos de aislamiento social.

RESUMO Este estudo teve por objetivo analisar o impacto do isolamento social decorrente da pandemia de Covid-19 sobre a vida familiar, com ênfase na vivência da maternidade e na relação com os filhos. Participaram 20 mães de camadas sociais médias, de 29 a 45 anos, que mantinham atividades laborais a distância e estavam em isolamento social. Foram realizadas entrevistas individuais em profundidade por meio digital. O material coletado foi transcrito e submetido à análise de conteúdo temática. Os resultados mostraram que as mudanças impostas pela pandemia impactaram diretamente a vida familiar, explicitando as desigualdades de gênero na organização da rotina, distribuição de tarefas domésticas e cuidados parentais. Observou-se uma relação ambivalente das mães com a maternidade e com seus imperativos sociais, que reverberam no vínculo que estabelecem com seus filhos. A análise revela que a sobrecarga emocional e física contribui para exacerbar sentimentos de culpa e solidão vivenciados na relação com a maternidade, além de evidenciar conflitos no desempenho dos papéis de mãe, esposa e profissional. As entrevistadas demonstraram exaustão com as demandas domésticas e de cuidados com os filhos, além de conflitos relacionados ao descompasso entre expectativas e padrões sociais que regulam o exercício da maternidade e suas experiências pessoais como mães. As conclusões sugerem a presença de uma crise identitária relacionada aos ideais sociais vinculados às vivências da maternidade, o que convida a pensar na urgência de se olhar para o sofrimento materno, buscando compreender as dimensões subjetivas das transformações que perpassam essa experiência na vigência do isolamento social.

https://doi.org/10.4025/psicolestud.v29i1.55777

Solidão e Sobrecarga Materna em Tempos de Pandemia de COVID-19 à Luz da Escuta Psicanalítica dos Vínculos
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Emidio, Thassia Souza

; Okamoto, Mary Yoko

; Santos, Manoel Antônio dos

Psico-USF

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2023, Volume 28 N. 3 Pages 505 - 520

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract This study aimed to analyze how domestic confinement resulting from the COVID-19 pandemic impacted motherhood among working women in a home office situation. This was an exploratory study, employing a longitudinal design and the theoretical framework of the psychoanalysis of bonds. Between April and July 2020, online interviews were conducted with 20 mothers from middle social strata, aged 29 to 45. One year later, new interviews were conducted with 10 participants, all transcribed and subjected to thematic analysis. The results showed that, compared to the initial period of the pandemic, mothers were close to physical and psychological exhaustion due to continuous overwork and lack of social and family support. These factors had deleterious impacts on the participants’ mental health, leading to reports of suffering and psychological helplessness. The search for medicalization reveals an individualized perception of the problem and an attempt to demonstrate stoicism to mitigate the suffering resulting from this experience.

Resumen Este estudio tuvo como objetivo analizar el impacto del confinamiento doméstico debido a la pandemia de COVID-19 en la maternidad de mujeres trabajadora en situación de teletrabajo. Se trata de un estudio exploratorio, con diseño longitudinal y marco teórico del psicoanálisis de los vínculos. Entre abril y julio de 2020 se realizaron entrevistas online a 20 madres de clases sociales medias, de 29 a 45 años; un año después, se realizaron nuevas entrevistas con 10 participantes. Las entrevistas fueron transcritas y analizadas mediante análisis temático. Los resultados mostraron que, en comparación con el período inicial de la pandemia, las madres experimentaron un acercamiento al agotamiento físico y psicológico por el exceso de trabajo y la falta de apoyo social y familiar, con impactos deletéreos en la salud mental de las participantes, relatos de sufrimiento e impotencia psicológica. La búsqueda de la medicalización revela una percepción individualizada del problema y un intento de demostrar estoicismo para aliviar el sufrimiento resultante de esta experiencia.

Resumo Este estudo teve por objetivo analisar o impacto do confinamento doméstico provocado pela pandemia de COVID-19 sobre o exercício da maternidade em mulheres trabalhadoras em situação de home office. Trata-se de um estudo exploratório, com delineamento longitudinal e referencial teórico da psicanálise dos vínculos. Entre abril e julho de 2020 foram realizadas entrevistas on-line com 20 mães de camadas sociais médias, de 29 a 45 anos. Um ano depois foram realizadas novas entrevistas com 10 participantes, todas transcritas e analisadas por meio da análise temática. Os resultados apontaram que, em comparação com o período inicial da pandemia, as mães mostraram-se próximas do esgotamento físico e psíquico devido ao excesso de trabalho contínuo e falta de apoio social e familiar, com impactos deletérios na saúde mental das participantes, relatos de sofrimento e desamparo psicológico. A busca pela medicalização revela uma percepção individualizada do problema e uma tentativa de demonstrar estoicismo para atenuar o sofrimento decorrente dessa experiência.

https://doi.org/10.1590/1413-82712023280307

Effect of Anodization on the Stress Corrosion Cracking Behavior of The AZ61 Magnesium Alloy in 0.1 M NaCl Solution
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Okamoto, Fábio

; Oliveira, Mara Cristina Lopes de

; Silva, Adenilson Almeida

; Droppa Jr, Roosevelt

; Antunes, Renato Altobelli

Materials Research

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 26 elocation e20220357

Abstract: En | Text: En | PDF: En

In the present work, the AZ61 alloy, one of the most important commercial structural magnesium alloys, was anodized in three different alkaline electrolytes consisting of 3 M KOH + 0.15 M Na2SiO3 + 0.1 M Na2B4O7.10H2O, 3 M KOH + 0.5 M Na3PO4 and 3 M KOH + 0.50 M Na2SiO3. The treatment was conducted at two different current densities, 20 and 30 mA.cm-2 for 10 minutes. The anodized layers were characterized by scanning electron microscopy, X-ray diffractometry and X-ray photoelectron spectroscopy. The corrosion resistance was assessed by potentiodynamic polarization tests. The SCC behavior was studied using slow strain rate tests in 0.1 M NaCl solution at room temperature. Conventional tensile tests were also conducted in air. The susceptibility to SCC was dependent on the morphology of the anodized film. The composition of the electrolyte and the current density of the anodization treatment affected the SCC susceptibility of the AZ61 alloy. The best corrosion resistance and the lowest susceptibility to SCC were obtained for samples anodized in the borate-containing electrolyte at 30 mA.cm-2. The smooth and compact surface morphology of the anodized film obtained in this condition was the main reason for the improved SCC behavior of the AZ61 alloy.

https://doi.org/10.1590/1980-5373-mr-2022-0357

Memória, desmentida e traumatismo social sob a ótica da Psicanálise das Configurações Vinculares
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Maia, Bruna Bortolozzi

; Santos, Manoel Antônio dos

; Okamoto, Mary Yoko

Psicologia USP

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 34 elocation e200214

Abstract Denialist discourses and the downplayed harmful effects of the civil-military dictatorship by high-ranking Brazilian government officials are emblematic examples of negationist attitudes towards narratives of social suffering. This theoretical study addresses the psychological processes of erasing traumatic social memories and their effects on psychic transmission based on psychoanalysis of linking configurations according to Puget and Berenstein. By mobilizing the concepts of social memory, denial, trauma and social trauma, we argue that negating traumatic facts generates a double violence: on the one hand, it produces gaps in history and a non-work linking that favors transgenerational psychic transmissions; on the other, it attacks the individuals’ social belonging and narcissistic constitution. We thus conclude by pointing out the need to create a listening device for social trauma that opposes denial, ensuring the right guaranteed by the Universal Declaration of Human Rights of people’s access to their own history.

Résumé Le discours négationniste et la minimisation des effets néfastes de la dictature civilo-militaire par des personnalités gouvernementales de haut rang sont des exemples emblématiques du déni des histoires de souffrance sociale. Cette étude théorique s’intéresse aux processus psychologiques d’effacement des souvenirs sociaux traumatisants et leurs effets sur la transmission psychique basée sur la perspective de la psychanalyse des liens proposée par Puget et Berenstein. En mobilisant les concepts de mémoire sociale, négationnisme, traumatisme et traumatisme social, nous soutenons que le déni des faits traumatiques engendre une double violence: d’une part, il produit des lacunes dans l’histoire et un non-travail contraignant qui favorise les transmissions psychiques transgénérationnelles ; d’autre part, il attaque l’appartenance sociale et la constitution narcissique des sujets. Nous concluons sur la nécessité de créer un dispositif d’écoute du traumatisme social opposé au négationnisme, en assurant le droit garanti par la Déclaration Universelle des Droits de l’Homme d’accès des peuples à leur propre histoire.

Resumen El discurso negacionista y la minimización de los efectos nocivos de la dictadura civil-militar por parte de altas figuras gubernamentales son ejemplos emblemáticos de la desmentida de las historias de sufrimiento social. Este estudio teórico aborda los procesos psicológicos de borrado de las memorias sociales traumáticas y sus efectos en la transmisión psíquica, desde la perspectiva del Psicoanálisis de las Configuraciones Vinculares, a la luz de Puget y Berenstein. Movilizando los conceptos de memoria social, desmentida, trauma y trauma social, argumentamos que la negación de los hechos traumáticos genera una doble violencia: por un lado, produce vacíos en la historia y un no-trabajo vinculante que favorece las transmisiones psíquicas transgeneracionales y, por otro lado, ataca la pertenencia social y la constitución narcisista de los sujetos. En vista de ello, concluimos con la necesidad de crear un dispositivo de escucha de los traumas sociales en la dirección opuesta a la negación, garantizando el derecho garantizado por la Declaración Universal de los Derechos Humanos del acceso de los pueblos a su propia historia.

Resumo O discurso negacionista e a minimização dos efeitos nefastos da ditadura civil-militar por figuras do alto escalão do governo são exemplos emblemáticos da desmentida de histórias de sofrimento social. Este estudo teórico aborda os processos psicológicos de apagamento de memórias sociais traumáticas e seus efeitos na transmissão psíquica, da perspectiva da Psicanálise das Configurações Vinculares, à luz de Puget e Berenstein. Mobilizando os conceitos de memória social, desmentida, trauma e traumatismo social, argumentamos que a denegação de fatos traumáticos gera uma dupla violência: por um lado, produz lacunas na história e um não-trabalho vincular que favorece transmissões psíquicas transgeracionais e, por outro, atenta contra o pertencimento social e a constituição narcísica dos sujeitos. À vista disso, concluímos pela necessidade de criar um dispositivo de escuta dos traumatismos sociais na contramão da desmentida, garantindo o direito assegurado pela Declaração Universal dos Direitos Humanos do acesso do povo à própria história.

https://doi.org/10.1590/0103-6564e200214

FECHAMENTO DAS ESCOLAS DURANTE A PANDEMIA DE COVID-19: EXPERIÊNCIAS MATERNAS COM FILHOS EM IDADE ESCOLAR
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Okamoto, Mary Yoko

; Santos, Manoel Antônio dos

; Emidio, Thassia Souza

Psicologia Escolar e Educacional

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 27 elocation e244702

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT This study aimed to understand mothers’ experiences of school closures due to social distancing measures imposed to combat the COVID-19 pandemic and its impacts on family ties and the perception of motherhood. Twenty middle-class women aged between 29 and 45 who accompanied their children to school activities at home during this period took part in the study. Individual semi-structured interviews were carried out remotely. The results showed that the pandemic has resulted in significant changes in family ties. The transition to remote classes has led to an accumulation of activities undertaken by mothers in the domestic context, resulting in overload and requiring extra dedication to their children’s education. In addition, the participants were reflective about the bond with their children and the values related to education. The overload experienced by the women was highlighted, with potential repercussions on the mental health and well-being of their families.

RESUMEN Este estudio tuvo por objetivo comprender las experiencias maternas ante el cierre de las escuelas resultante de las medidas de distanciamiento social impuestas por el combate a la pandemia de COVID-19, y sus impactos en los lazos familiares y en la percepción de la maternidad. Participaron en la investigación 20 mujeres de clase media con edades comprendidas entre los 29 y los 45 años que acompañaron a sus hijos a las actividades escolares en casa durante en ese período. Las entrevistas individuales semiestructuradas se realizaron a distancia. Los resultados apuntaron que la pandemia ha provocado cambios significativos en los vínculos familiares. La transición a las clases a distancia ha provocado una acumulación de actividades realizadas por las madres en el contexto doméstico, lo que ha dado lugar a una sobrecarga y ha exigido una dedicación adicional a la educación de sus hijos. Además, las participantes reflexionaron sobre el vínculo con sus hijos y los valores relacionados con la educación. Se evidenció la sobrecarga experimentada por las mujeres, con posibles repercusiones en su salud mental y en el bienestar de sus familias.

RESUMO Este estudo teve por objetivo compreender as experiências maternas diante do fechamento das escolas, decorrente das medidas de distanciamento social impostas pelo combate à pandemia de COVID-19, e seus impactos nos vínculos familiares e na percepção da maternagem. Participaram da pesquisa 20 mulheres de camadas sociais médias, com idades entre 29 e 45 anos, que acompanharam seus filhos nas atividades escolares desenvolvidas em casa nesse período. Foram realizadas entrevistas individuais semiestruturadas por meio remoto. Os resultados encontrados apontaram que a pandemia resultou em mudanças significativas nos vínculos familiares. A transposição para aulas remotas acarretou um acúmulo de atividades assumidas pelas mães no contexto doméstico, resultando em sobrecarga e exigindo uma dedicação extra à educação dos filhos. Além disso, as participantes mostraram-se reflexivas sobre a vinculação com seus filhos e os valores relativos à educação. Evidenciou-se a sobrecarga vivida pelas mulheres, com possíveis repercussões na saúde mental e no bem-estar de suas famílias.

https://doi.org/10.1590/2175-35392023-244702

Association between intraoperative hypotension and postoperative nausea and vomiting: a retrospective analysis of 247 thyroidectomy cases
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Nakatani, Hitomi

; Naito, Yusuke

; Ida, Mitsuru

; Sato, Mariko

; Okamoto, Naoko

; Nishiwada, Tadashi

; Kawaguchi, Masahiko

Brazilian Journal of Anesthesiology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 73 N. 5 Pages 635 - 640

Abstract: En | Text: En | PDF: En

Abstract Background: Postoperative nausea and vomiting (PONV) are major complications after general anesthesia. Although various pathways are involved in triggering PONV, hypotension plays an important role. We hypothesized that intraoperative hypotension during general anesthesia might be responsible for the incidence of PONV. Methods: We retrospectively investigated patients who underwent thyroidectomy. The initial blood pressure measured before induction of anesthesia was used as the baseline value. The systolic blood pressure measured during the operation from the start to the end of anesthesia was extracted from anesthetic records. The time integral value when the measured systolic blood pressure fell below the baseline value was calculated as area under the curve (AUC) of s100%. Results: There were 247 eligible cases. Eighty-eight patients (35.6%) had PONV. There was no difference in patient background between the patients with or without PONV. Univariate analysis showed that the total intravenous anesthesia (TIVA) (p = 0.02), smoking history (p = 0.02), and AUC-s100% (p = 0.006) were significantly associated with PONV. Multiple logistic regression analysis revealed that TIVA (OR: 0.54, 95% CI: 0.29–0.99), smoking history (OR: 0.60, 95% CI: 0.37–0.96), and AUC-s100% (OR: 1.006, 95% CI: 1.0–1.01) were significantly associated with PONV. Conclusion: Intraoperative hypotension evaluated by AUC-s100% was related to PONV in thyroidectomy.

https://doi.org/10.1016/j.bjane.2021.02.029

Retinopathy of prematurity: risk factors for its development in two neonatal intensive care units in Paraná-Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Mayer, Sylvia M. F.

; Mazarollo, Larissa K. G.

; Okamoto, Cristina

; Moreira, Luciane

; Hopker, Luisa M.

Arquivos Brasileiros de Oftalmologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2022, Volume 85 N. 4 Pages 364 - 369

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivos: Avaliar duas unidades de terapia intensiva neonatais do Paraná e identificar os fatores de risco que levam ao desenvolvimento da retinopatia da prematuridade nestas unidades neonatais. Metodos: Foi realizado um estudo de coorte, prospectivo, com avaliação dos bebês prematuros examinados no período de 12 meses com idade gestacional ≤32 semanas e/ou com peso de nascimento ≤1500 gramas, internados na unidade de cuidados intensivos neonatais do Hospital do Trabalhador e do Hospital infantil Waldemar Monastier, que recebe neonatos transportados das maternidades de todo o estado do Paraná. Resultados: A incidência de retinopatia da prematuridade foi maior no Hospital Infantil Waldemar Monastier, entre os prematuros que necessitaram de transporte do local de nascimento para a unidade de cuidados intensivos (52,2% vs 29,6%), Os fatores de risco associados ao desenvolvimento da doença foram; Maior número de dias de internamento, baixa idade gestacional ao nascimento, maior tempo de uso de oxigênio, uso de drogas vasoativas, ausência de uso de corticoide pré-natal, presença de hemorragia intracraniana e qualquer tipo de alteração da glicemia. Conclusão: Os cuidados neonatais precoces e o transporte do recém-nascido pré- termo podem influenciar a ocorrência e o prognostico da retinopatia da prematuridade.

ABSTRACT Purpose: Evaluate the patients in two neonatal intensive care units in Paraná/Brazil and identify the risk factors for the development of retinopathy of prematurity. Methods: We performed a prospective cohort study on premature infants with gestational age ≤32 wk and/or with birth weight ≤1500 g who were admitted to the neonatal intensive care unit of Hospital do Trabalhador and Hospital Infantil Waldemar Monastier. These hospitals admit patients referred from other maternity hospitals in the state of Paraná. The study duration was 12 mon. Results: The incidence of retinopathy of prematurity was higher in the Hospital Infantil Waldemar Monastier than in the Hospital do Trabalhador for premature infants who needed to be transported from their birthplace to the intensive care unit (52.2% vs. 29.6%). The following risk factors were associated with the development of the disease: longer hospitalization, low gestational age at birth, longer oxygen use, vasoactive drugs use, no antenatal corticosteroids use, intracranial hemorrhage, and any glycemic disorder. Low birth weight was an independent risk factor for the development of retinopathy of prematurity. Conclusion: Early neonatal care and transportation of premature infants may influence the occurrence and prognosis of retinopathy of prematurity.

https://doi.org/10.5935/0004-2749.20220049

A vitamina C na esquizofrenia apresenta benefício? Estudo preliminar com análise comportamental em ratos
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Okamoto, Juliana Naomi

; Martins, Mario Luiz Watanabe Gomes

; Henna Neto, Jorge

Jornal Brasileiro de Psiquiatria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jul 2022, Volume 71 N. 3 Pages 186 - 192

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo O objetivo deste estudo foi analisar em ratos modelos de esquizofrenia, induzidos pela administração de cetamina, a possibilidade dos efeitos benéficos do ácido ascórbico na esquizofrenia, por meio do teste comportamental. Métodos O estudo preliminar foi simples-cego e randomizado. Foi realizado o protocolo de psicose por cetamina em 24 ratos Wistar submetidos posteriormente à análise comportamental. No primeiro grupo, foram administradas: água e cetamina; no segundo: ácido ascórbico e cetamina; no terceiro: antipsicótico, ácido ascórbico e cetamina; e no quarto: antipsicótico, água e cetamina. A análise comportamental foi feita por meio do Open Field Test, considerado o método-padrão para avaliar comportamento em modelos animais de esquizofrenia. A análise estatística foi realizada pelo software IBM-SPSS, por meio dos Modelos Lineares Generalizados. Resultados O tratamento em monoterapia de haloperidol (Média Quadrante: 44,5 ± 15,8; IC: 13,54-75,46/Média Centro: 2,67 ± 0,67; IC: 1,63-4,35) e aquele em conjunto com a vitamina C (Média Quadrante: 38,67 ± 15,8; IC: 7,71-69,52/Média Centro: 2,00 ± 0,58; IC: 1,14-3,52) demonstraram benefícios nos ratos modelos de esquizofrenia induzidos por cetamina (Média Quadrante: 108,5 ± 15,8; IC: 77,54-139,46/Média Centro: 11,33 ± 1,37; IC: 8,94-14,37) (p < 0,001). O tratamento isolado com a vitamina C não apresentou resultado significante (Média Quadrante: 62,00 ± 15,8; IC: 31,04-92,96/Média Centro: 7,00 ± 1,08; IC: 5,17-9,47). Conclusão A associação de antipsicótico e vitamina C e somente o antipsicótico demonstraram efeito terapêutico em relação aos controles. A vitamina C isolada não apresentou benefício.

ABSTRACT Objective The objective of this study was to analyze in rats models of schizophrenia, induced by the administration of ketamine, the possibility of the beneficial effects of ascorbic acid in schizophrenia, through the behavioral test. Methods This preliminary study was simple blind and randomized. The ketamine psychosis protocol was carried out in 24 Wistar rats, which were subsequently submitted to behavioral analysis. The first group was supplied with: water and ketamine; the second: ascorbic acid and ketamine; the third: antipsychotic, ascorbic acid and ketamine; the fourth: antipsychotic, water and ketamine. Behavioral analysis was performed using the Open Field Test, considered the standard method for assessing behavior in animal models of schizophrenia. Statistical analysis was performed by the IBM-SPSS software, using the Generalized Linear Models. Results Treatment in haloperidol monotherapy (Quadrant Average: 44.5 ± 15.8; CI: 13.54-75.46/Center Average: 2.67 ± 0.67; CI: 1.63-4.35) and combined with vitamin C (Quadrant Average: 38.67 ± 15.8; CI: 7.71-69.52/Center Average: 2.00 ± 0.58; CI: 1.14-3.52), demonstrated benefits in the animal model of schizophrenia induced by ketamine (Quadrant Average: 108.5 ± 15.8; CI: 77.54-139.46/Center Average: 11.33 ± 1.37; CI: 8.94- 14.37) (p < 0.001). The isolated treatment with vitamin C did not show a significant result (Quadrant Average: 62.00 ± 15.8; CI: 31.04-92.96/Mean Average: 7.00 ± 1.08; CI: 5.17-9.47). Conclusion The association of antipsychotic and vitamin C and only the antipsychotic demonstrated a therapeutic effect respecting to controls. Vitamin C manage separately had no benefit.

https://doi.org/10.1590/0047-2085000000373

Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome in children: a brief literature review
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Okamoto, Cristina Terumy

; Chaves, Hanne Lise

; Schmitz, Mateus José

Revista Paulista de Pediatria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2022, Volume 40 elocation e2021087

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as características clínicas, diagnósticas e de tratamento da síndrome de febre periódica, estomatite aftosa, faringite e adenite (PFAPA). Fontes de dados: Revisão de literatura na base de dados PubMed, feita por meio de descritores específicos para identificar todos os artigos publicados em língua inglesa nos últimos três anos. Dos 38 artigos encontrados, foram encaminhados para leitura integral 13 publicações após seleção de títulos e análise de abstract. Estudos relevantes encontrados nas referências dos artigos revisados também foram incluídos. Síntese dos dados: A PFAPA é traduzida do inglês periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis. Caracterizada por etiologia ainda incerta e possivelmente multifatorial, seus sintomas são acompanhados por episódios recorrentes de febre associados a um desenvolvimento pôndero-estatural preservado. É uma doença autolimitada de curso benigno, com remissão em dois a três anos, sem interferências significativas no desenvolvimento do paciente pediátrico. O tratamento consiste em três pilares: interrupção da crise febril, aumento do intervalo entre crises e remissão. Conclusões: Apesar de várias tentativas de estabelecer critérios atuais mais sensíveis e específicos, o diagnóstico da síndrome PFAPA ainda é clínico e de exclusão com base nos critérios de Marshall modificados. As opções farmacológicas mais utilizadas para o tratamento são a prednisolona e betametasona; colchicina pode ser utilizada como profilaxia e o tratamento cirúrgico com tonsilectomia pode ser considerado em casos selecionados.

ABSTRACT Objective: To describe clinical, diagnostic and therapeutic characteristics of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. Data source: Literature review in the PubMed database by using specific descriptors to identify all articles published in the English language in the last three years; 38 articles were found. After performing selection of titles and abstract analysis, 13 out of the 38 articles were fully read. Relevant studies found in the references of the reviewed articles were also included. Data synthesis: The PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis and cervical Adenitis) is a medical condition grouped among the periodic fever syndromes. The etiology is uncertain, but possibly multifactorial, and its symptoms are accompanied by recurrent febrile episodes although weight and height development are preserved. It is a self-limiting disease of benign course with remission of two to three years without significant interference in the patient's overall development. Treatment consists of three pillars: interruption of febrile episodes, increase in the interval between episodes, and remission. Conclusions: Despite several attempts to establish more sensitive and specific criteria, the diagnosis of PFAPA syndrome is still clinical and reached by exclusion, based on the modified Marshall's criteria. The most common pharmacological options for treatment include prednisolone and betamethasone; colchicine may be used as prophylaxis, and surgical treatment with tonsillectomy can be considered in selected cases.

https://doi.org/10.1590/1984-0462/2022/40/2021087in

10.

Report of a clinical and laboratory management of cell therapy for knee cartilage in the face of mycoplasma contamination
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Zorzi, Alessandro Rozim

; Antonioli, Eliane

; Godoy, Juliana Aparecida Preto de

; Okamoto, Oswaldo Keith

; Kondo, Andrea Tiemi

; Kutner, José Mauro

; Kaleka, Camila Cohen

; Cohen, Moisés

; Ferretti, Mario

einstein (São Paulo)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2022, Volume 20 elocation eRC6918

Abstract: En | Text: En | PDF: En

ABSTRACT To describe a case of autologous chondrocyte implantation after cell culture contamination by Mycoplasma pneumoniae and the measures taken to successfully complete cell therapy in a patient with focal chondral lesion. A 45-year-old male patient, complaining of chronic pain on the knee and no history of trauma. He had a chondral lesion in the trochlear region of the femur and clinical tests compatible with pain in the anterior compartment of the knee. Conservative treatment failed to alleviate symptoms. Surgical treatment was indicated, but due to the size of the lesion, membrane-assisted autologous chondrocyte implantation was the technique of choice. Cartilage biopsies were collected from the intercondylar region of the distal femur. After isolation, chondrocytes were expanded ex vivo in a trained laboratory, for three weeks, and seeded onto a commercially available collagen membrane prior to implantation in the knee. Two days before surgery, a cell culture sample tested positive for Mycoplasma pneumoniae. The source of contamination was found to be autologous blood serum, extracted from the patient´s peripheral vein, and used to supplement the cell culture medium. After treating the patient with antibiotics, all procedures were repeated and the new final cell product, free from contaminants, was successfully implanted. We discuss the strategies available to deal with this situation, and describe the results of this particular case, which led to modifications in the autologous chondrocyte implant protocol.

https://doi.org/10.31744/einstein_journal/2022rc6918

11.

Absence of an association between serum interleukin-6 and brain-derived neurotrophic factor in drug-naïve first-episode major depression
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Yoshimura, Reiji

; Okamoto, Naomichi

; Kinishi, Yuki

; Ikenouchi, Atsuko

Archives of Clinical Psychiatry (São Paulo)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 48 N. 5 Pages 229 - 230

Abstract: En | Text: En | PDF: En

ABSTRACT Peripheral and central cytokine interleukin-6 (IL-6) levels play an important role in the pathophysiology of major depression (MD). We investigated the association between serum levels of IL-6 and brain-derived neurotrophic factor (BDNF) in drug-naïve, first-episode patients with MD. This study included 28 patients (male/female: 11/17; mean [standard deviation] age, 46.7 [11.9] years) who met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria for MD without any physical diseases. We evaluated the severity of depression using the Hamilton Rating Scale for Depression. No associations were found between serum levels of IL-6 and BDNF (r=-0.102, P =0.605). These results suggest that IL-6 does not influence BDNF and vice versa, but both act in a peripheral manner.

https://doi.org/10.15761/0101-60830000000312

12.

Cannabinoids in Neurology - Position paper from Scientific Departments from Brazilian Academy of Neurology
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

BRUCKI, Sonia Maria Dozzi

; ADONI, Tarso

; ALMEIDA, Carlos Mauricio Oliveira

; ANDRADE, Daniel Ciampi de

; ANGHINAH, Renato

; BARBOSA, Luciana Mendonça

; BAZAN, Rodrigo

; CARVALHO, Alzira Alves de Siqueira

; CARVALHO, William

; CHRISTO, Paulo Pereira

; COLETTA, Marcus Della

; CONFORTO, Adriana Bastos

; CORREA-NETO, Ylmar

; ENGELHARDT, Eliasz

; FRANÇA JUNIOR, Marcondes Cavalcante

; FRANCO, Clelia

; VON GLEHN, Felipe

; GOMES, Helio Rodrigues

; HOULY, Caroline Gomes de Barros

; KAUP, Alexandre Ottoni

; KOWACS, Fernando

; KANASHIRO, Aline

; LOPES, Victor Gonçalves

; MAIA, Débora

; MANREZA, Maria

; MARTINEZ, Alberto Rolim Muro

; MARTINEZ, Sandra Cristina Gonçalves

; NADER, Saulo Nardy

; NEVES, Luciana de Oliveira

; OKAMOTO, Ivan Hideyo

; OLIVEIRA, Rogério Adas Ayres de

; PEIXOTO, Fabiano de Melo

; PEREIRA, Cristiana Borges

; SABA, Roberta Arb

; SAMPAIO, Leticia Pereira de Brito

; SCHILLING, Lucas Porcello

; SILVA, Marcus Tulius Teixeira

; SILVA, Emanuelle Roberta

; SMID, Jerusa

; SOARES, Cristiane Nascimento

; SOBREIRA-NETO, Manoel

; SOUSA, Nise Alessandra de Carvalho

; SOUZA, Leonardo Cruz de

; TEIVE, Hélio Afonso Ghizoni

; TERRA, Vera Cristina

; VALE, Matheus

; VIEIRA, Vitor Mendes Grise

; ZANOTELI, Edmar

; PRADO, Gilmar

Arquivos de Neuro-Psiquiatria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2021, Volume 79 N. 4 Pages 354 - 369

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Os canabinoides compreendem os endocanabinoides, fitocanabinoides e os canabinoides sintéticos e desempenham ações no sistema nervoso central e periférico. Uma quantidade enorme de publicações tem sido lançada nos últimos anos, embora a cannabis seja conhecida por milênios. Os Departamentos Científicos da Academia Brasileira de Neurologia descreveram as evidências do uso médico em suas áreas. A literatura está em constantes mudanças e possíveis novas evidências podem surgir nos próximos dias ou meses. A prescrição dessas substâncias deve ser discutida com os pacientes e suas famílias, com conhecimento sobre eventos adversos e sua eficácia.

ABSTRACT Cannabinoids comprehend endocannabinoids, phytocannabinoids, and synthetic cannabinoids, with actions both in the central and peripherical nervous systems. A considerable amount of publications have been made in recent years, although cannabis has been known for over a thousand years. Scientific Departments from the Brazilian Academy of Neurology described evidence for medical use in their areas. Literature is constantly changing, and possible new evidence can emerge in the next days or months. Prescription of these substances must be discussed with patients and their families, with knowledge about adverse events and their efficacy.

https://doi.org/10.1590/0004-282x-anp-2020-0432 1049 downloads

13.

Vortioxetine improved olfactory reference syndrome in a patient with major depressive disorder: A case report
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Yoshimura, Reiji

; Konishi, Yuki

; Okamoto, Naomichi

; Ikenouchi, Atsuko

Archives of Clinical Psychiatry (São Paulo)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2021, Volume 48 N. 2 Pages 128 - 128

Abstract: En | Text: En | PDF: En

https://doi.org/10.15761/0101-60830000000293 116 downloads

14.

CLINICAL OUTCOMES AFTER UNICOMPARTMENTAL KNEE ARTHROPLASTY FOR OSTEONECROSIS OF THE KNEE
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

KAMENAGA, TOMOYUKI

; HIRANAKA, TAKAFUMI

; HIDA, YUICHI

; FUJISHIRO, TAKAAKI

; OKAMOTO, KOJI

Acta Ortopédica Brasileira

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2021, Volume 29 N. 1 Pages 12 - 16

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Embora a Artroplastia Unicompartimental do Joelho (AUJ) de Oxford pareça ser um procedimento adequado para o tratamento da Osteonecrose Espontânea do Joelho (ONEJ), o afrouxamento asséptico do componente tibial foi a principal causa de fracassos na AUJ medial. Este estudo teve por objetivo observar desfechos clínicos de curto e médio prazo após AUJ, além de determinar se a presença de lesão tibial interfere nos desfechos clínicos e radiográficos do procedimento. Métodos: Sessenta pacientes (idade média de 73,1 ± 6.6 anos) diagnosticados com ONEJ no côndilo medial do fêmur e tratados com AUJ foram divididos em dois grupos por meio de imagens ponderadas em T1 obtidas em exames pré-operatórios de ressonância magnética (RM): grupo F (lesão necrótica limitada ao fêmur) e grupo T (lesão necrótica espalhada para a tíbia). Os valores obtidos no Oxford Knee Score (OKS) e o ângulo de flexão máxima (AFM), bem como achados radiográficos (linha radiotransparente e subsidência) para cada grupo foram comparados usando teste t não-pareado. Resultados: Ambos os grupos apresentaram melhoria significativa nos valores de OKS e AFM no último acompanhamento, mas sem diferenças significativas nos desfechos clínicos e radiográficos. Conclusão: AUJ é um procedimento confiável para o tratamento de ONEJ a curto e médio prazo. A presença de lesões da tíbia, diagnosticada por meio da RM pré-operatória, não afetou os desfechos clínicos e radiográficos no pós-operatório. Nível de Evidência IV, Série de casos.

ABSTRACT Objective: Although the mobile-bearing Oxford unicompartmental knee arthroplasty (OUKA) seems an appropriate procedure to treat spontaneous osteonecrosis of the knee (SONK), aseptic tibial component loosening was the leading cause for medial UKA failure. This study aimed to observe short-term and midterm clinical outcomes following OUKA and determine whether tibial lesion affects the procedure clinical and radiographic outcomes. Methods: Sixty patients (mean age 73.1 ± 6.6 years) diagnosed with SONK in the medial femoral condyle and treated with OUKA were separated into two groups using T1-weighted preoperative magnetic resonance imaging (MRI): group F (necrotic lesion confined to the femur) and group T (necrotic lesion spread to the tibia). The Oxford Knee Score (OKS), maximum flexion angle (MFA), and radiographic findings (radiolucent line and subsidence) were compared between the two groups using unpaired t-test. Results: Both groups showed significant improvement in OKS and MFA values at the final follow-up, but without significant differences in the clinical and radiographic outcomes. Conclusion: OUKA is a reliable treatment procedure for SONK in the short and midterm. The presence of tibial lesions on preoperative MRI does not affect postoperative radiographic and clinical outcomes. Level of Evidence IV, Case Series.

https://doi.org/10.1590/1413-785220212901233328 505 downloads

15.

The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: a comparative histomorphometric, immunohistochemical and randomized clinical study
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

PEREIRA, Rodrigo dos Santos

; BONARDI, João Paulo

; OUVERNEY, Felippe Ricardo Frossard

; CAMPOS, Annelise Backer

; GRIZA, Geraldo Luiz

; OKAMOTO, Roberta

; HOCHULI-VIEIRA, Eduardo

Journal of Applied Oral Science

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2021, Volume 29 elocation e20200568

Abstract: En | Text: En | PDF: En

Abstract Objective The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.

https://doi.org/10.1590/1678-7757-2020-0568 1123 downloads

Showing

itens per page

Page of 10 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »